Acc tablets instructions for use. ACC powder: instructions for use. Mechanism of action and indications for use

Most diseases are always accompanied by a cough, so it is understandable that there is a desire to get rid of it faster. The range of anti-influenza and expectorants is wide. How to make the right choice? Not every medication is suitable for the treatment of dry or wet cough. So ACC can not always be used.

Ass medicine is a mucolytic, expectorant and detoxifying agent, prescribed for severe coughs in children and adults. This drug is able not only to dilute sputum, but also to effectively remove it from the lungs and bronchi, relieve inflammation, and improve the functioning of the secretory motor functions of the body. The ACC instruction states that it can be used in the presence of the following deviations in the state of health:

• acute or chronic bronchiolitis and bronchitis;
• sinusitis;
• asthma;
• pneumonia;
• pulmonary eczema;
• tuberculosis;
• otitis media;
• cold.

Even this is not all the possibilities of the ACC. Due to its medicinal properties, the drug is often used for cystic fibrosis, a hereditary disease caused by a gene mutation. In addition, it is often prescribed for the treatment of mild or prolonged inflammatory processes of the nasopharynx: tracheitis, acute rhinitis, nasopharyngitis, sinusitis, which are accompanied by the accumulation of a large amount of purulent mucus.

What kind of cough is ACC prescribed for?

If the house already has a package of the remedy, then before going to the pharmacy, you can independently study what kind of cough they drink ACC. However, complex medical terms and phrases will not be clear to everyone. Doctors recommend taking the drug with a wet productive cough - when excess viscous or too thick sputum accumulates in the bronchi.

ACC - at what age can children be given

Many young mothers ask: is it possible and from what age to give ACC to children? To which experienced pediatricians confidently answer: it is not only possible, but necessary. The main thing is to do it right:

• A child from 2 years old to 6 years old can only be given ACC 100 mg, which is available as a powder.
• Starting from the age of 7, treatment with ACC 200 mg is allowed. This medicine can be found in granules.
• For children 14 years of age and older, ACC 600 is available. Unlike other drugs, this type of medication is valid for 24 hours.
• As a syrup, medicine is allowed to be given to infants, but only under the supervision of a pediatrician.

How to use ACC

For convenience, many pharmaceutical companies began to produce the drug in several forms: granules, for example, with orange flavor, instant tablets, syrup. Each form has its own doses and framework for how to take ACC:

• It is extremely rare that the solution is prescribed for inhalation. If the nebulizer used for the procedure is equipped with a distribution valve, then 6 ml of a 10% powder solution should be used. If there is no such supplement, doctors recommend taking a 20% solution at the rate of 2-5 ml per 1 liter of water.
• With bronchoscopy, severe rhinitis, sinusitis, the use of ACC intratracheally is allowed. To clean the bronchi and nasal sinuses, a 5-10% solution is used. The diluted liquid must be instilled into the nose and ears up to 300 mg per day.
• With the parenteral method of application, ACC is administered intramuscularly or intravenously. In the latter case, the ampoule must be diluted with sodium chloride or dextrose in proportions of 1 to 1.

ACC-long - instructions for use

The ACC agent marked long differs from ordinary tablets or powder in that the effect of exposure to it lasts not 5-7 hours, but the whole day. The medicine is produced in the form of large effervescent tablets and is intended for oral administration 1 tablet 1 time / day, in the absence of other doctor's recommendations. Additionally, along with the medicine, it is necessary to drink up to one and a half liters of liquid, which enhances the mucolytic effect.

How to breed ACC long:

1. Pour into a glass of clean chilled boiled water, put a tablet on the bottom.
2. Wait for the effervescent effect to pass and the capsule to completely dissolve.
3. Drink the solution immediately after dissolution.
4. Sometimes, before drinking ACC, the diluted drink can be left for several hours.

ACC powder - instructions for use

ACC powder is used in the following doses:

• adolescents over 14 years of age and adults are prescribed up to 600 mg of acetylcysteine, the intake is divided into 1-3 approaches;
• a child under 14 years of age is recommended to give the same dose of the drug, but divided into several doses per day;
• babies under 6 years old can be given 200-400 mg of powder per day.

ACC powder for both adults and children should be drunk after meals, and the composition from the bag must be properly prepared. In what water to dissolve ACC depends on your preferences, but remember: the best result will be achieved if you dilute the medicine with half a glass of hot water. However, orange-flavored baby granules can be dissolved in lukewarm, boiled water.

Effervescent tablets ACC - instructions for use

Effervescent tablets of acetylcysteine ​​are diluted with water according to the same system as regular powder. The dose of the drug, in the absence of other doctor's recommendations, is:

• for mild infectious diseases, adults - 1 tablet of ACC 200 2-3 times a day, for 5-7 days;
• with chronic cough, bronchitis or cystic fibrosis, the drug is drunk for a longer period, and its dose for adults is 2 capsules of ACC 100 three times a day.

ACC syrup for children - instructions

Sweet ACC syrup is prescribed for children from the age of two and older, in the diagnosis of mild colds or chronic bronchitis. The medicine is taken orally, for 5 days, immediately after eating. The dosage of the syrup is chosen by the attending physician. If no recommendations have been received from the pediatrician, then the ACC will be the guide - the official instructions for use from the manufacturer, which says that you can take the medicine:

• adolescents 10 ml 3 times / day;
• if the child is from 6 to 14 years old, then 5 ml 3 times / day;
• for babies 5 years old, the dose of the drug is 5 ml 2 times / day.

Remove the children's syrup from the vial using a measuring syringe. The device comes with medication. The instructions for using the syringe are as follows:

1. Press on the vial cap, turn it clockwise until it clicks.
2. Remove the cap from the syringe, insert the hole into the neck and press the syringe until it stops.
3. Turn the bottle upside down, pull the syringe handle towards you, measuring the required dose of syrup.
4. If bubbles appear inside the syringe, lower the plunger slightly.
5. Slowly pour the syrup into the child's mouth and let the child swallow the medicine. While taking the drug, children should stand or sit.
6. After use, the syringe must be washed without soap.

Analogue of ACC

If you are looking for a cheap analogue of the ACC cough analogue, pay attention to the following medicines:

• Ambroxol, country of origin - Russia. It contains the same active ingredient and belongs to the category of mucolytic expectorants. Its price is about 40-50 rubles.
• Fluimucil, country of origin - Italy. It is intended to eliminate the first signs of a cold and cough, but can be used to facilitate the discharge of a viscous secretion from the nose. Its composition consists of 600 mg of acetylcysteine, citric acid, sorbitol and flavors. The price of the drug is about 300 rubles.
• Ambrobene, country of origin - Germany. It is produced as a syrup, which is based on another active substance - ambroxol hydrochloride. The medicine helps to cope with a protracted, poorly expectorated cough, removes sputum from the bronchi, and softens the airways. Its price ranges from 200 to 300 rubles.

ACC price for cough

The release form not only contributed to the freedom of choice of the buyer, but also significantly influenced how much ACC costs in pharmacies. More often, its price is very reasonable, which makes the medicine affordable for every social stratum of the population. However, in different cities and pharmacies, drug prices may vary slightly. The average cost of the drug is as follows:

• children's syrup - price up to 350 rubles;
• granulated ACC - up to 200 rubles;
• powder - 130-250 rubles;
• powder with orange and honey flavor - price from 250 r.

ACC - contraindications

Contraindications to the use of ACC are as follows:

• individual intolerance to the active substance;
• hypersensitivity to additional components of the drug;
• illness during pregnancy, during lactation, excluding artificial feeding;
• duodenal ulcer and stomach;
• liver failure;
• history of pulmonary hemorrhage.

In addition, the drug is highly undesirable to use together with other cough syrups, bronchodilators and antibiotics containing codeine and depressing expectorant reflexes. With caution, you should drink the medicine for those who have previously been diagnosed with venous varicose veins, adrenal diseases or abnormalities in the endocrine system.

Side effects of ACC

Overdose symptoms and side effects of ACC appear as:

• allergic reactions: skin itching, urticaria, dermatitis, laryngeal edema, anaphylactic shock;
• deterioration of health: muscle weakness, drowsiness, ringing in the ears, rapid heartbeat, migraine;
• stool disorder: severe diarrhea;
• indigestion: nausea, heartburn, the appearance of a gag reflex after taking the pills.

Video: ACC abstract

ACC - reviews

Anton, 54 years old

I suffered from a cough for a long time. I can’t say that he was dry, but the sputum still didn’t come out. I decided to go to the hospital and the doctor advised me to try ACC long in effervescent tablets. I drank the course, as it was said to the instructions for the medicine - 5 days. The cough has not gone away at all, but breathing has become much easier, and sputum is already coming out of the bronchi.

Anastasia, 32 years old

At the beginning of the treatment of a wet, persistent cough, a friend advised me to try ACC powder. When I came to the pharmacy, at first I was embarrassed because of the price of the medicine. It cost somewhere around 130 rubles, which is very strange and inexpensive compared to analogues. I decided to try it anyway and was not mistaken, the cold went away in 3 days, and my breathing returned to normal.

ACC - instructions for use. How to drink effervescent tablets, powder or cough syrup for adults and children ACC - all about medicines and health on the site

Name:

ACC (ACC)

Pharmacological
action:

Acetylcysteine ​​(ACC) - mucolytic, expectorant, which is used to thin sputum in diseases of the respiratory system, accompanied by the formation of thick mucus. Acetylcysteine ​​is a derivative of the amino acid cysteine.
The mucolytic effect of the drug has a chemical nature.
Due to the free sulfhydryl group, acetylcysteine ​​breaks the disulfide bonds of acid mucopolysaccharides, which leads to depolymerization of sputum mucoproteins and a decrease in mucus viscosity and promotes expectoration and discharge of bronchial secretions.
The drug remains active in the presence of purulent sputum.
Acetylcysteine also has antioxidant pneumoprotective properties, which is due to its binding by sulfhydryl groups of chemical radicals and, thus, their neutralization.

In addition, the drug helps to increase the synthesis of glutathione - an important factor in intracellular protection not only from oxidative toxins of exogenous and endogenous origin, but also from some cytotoxic substances.
This feature of acetylcysteine ​​makes it possible to effectively use the latter with an overdose of paracetamol.
After oral administration of acetylcysteine quickly and completely absorbed and undergoes metabolism in the liver with the formation of cysteine, a pharmacologically active metabolite, as well as diacetylcysteine, cystine, and further - mixed disulfides.
Bioavailability is very low - about 10%.
Cmax in blood plasma is reached 1-3 hours after administration. Plasma protein binding - 50%.
Acetylcysteine ​​is excreted by the kidneys as inactive metabolites (inorganic sulfates, diacetylcysteine).
T½ is determined mainly by rapid biotransformation in the liver and is about 1 hour. In the case of a decrease in liver function, T½ increases to 8 hours.

Indications for
application:

Acetylcysteine ​​is prescribed in all cases of diseases with accumulation in the bronchial tree and upper respiratory tract of thick viscous sputum, namely:
- acute and chronic bronchitis, including obstructive;
- bronchiolitis;
- tracheitis;
- bronchial asthma;
- bronchiectasis;
- cystic fibrosis;
- laryngitis;
- sinusitis;
- otitis media.

Mode of application:

Daily dose for the treatment of cystic fibrosis patients weighing more than 30 kg are used up to 800 mg.
Children from the 10th day of life and up to 2 years old use 50 mg 2-3 r / s.
At the age of 2-5 years - 400 mg per day, divided into 4 doses. From 6 years old - 600 mg / s (divided into 3 doses).
Treatment is continued for a long time, courses for several months (3-6).
In all other cases, the daily dose for children from 14 years of age and adults is 400-600 mg. From 6 to 14 years - 300-400 mg (divided into 2 doses), 2-5 years - 200-300 mg (divided into 2 doses).
Children from the 10th day of life and up to 2 years old use 50 mg 2-3 r / s.

In acute diseases without complications the drug is prescribed for 5-7 days.
In case of complications or in a chronic course, course treatment is possible (up to 6 months).
ACC is taken after a meal.
The tablet or the contents of the sachet must be dissolved in half a glass of liquid (cold tea, water, juice).

Side effects:

To describe the frequency of side effects, the following classification is used: very often (≥1/10), often (≥1/100,<1/10), нечасто (≥1/1000, <1/100), редко (≥1/10 000, <1/1000), очень редко (<1/10 000).
From the side of the cardiovascular system: infrequently - tachycardia, arterial hypotension.
From the side of the nervous system: infrequently - headache.
From the side of the skin: infrequently - allergic reactions (itching, urticaria, exanthema, eczema, rash, angioedema).
From the organ of hearing: infrequently - ringing in the ears.
From the respiratory system: rarely - shortness of breath, bronchospasm (mainly in patients with hyperreactivity of the bronchial system, which is associated with asthma), rhinorrhea.

From the digestive tract: infrequently - heartburn, dyspepsia, stomatitis, abdominal pain, nausea, vomiting, diarrhea, bad breath.
General disorders: infrequently - fever.
Some severe skin reactions (Stevens-Johnson and Lyell syndromes) have been reported.
With the use of acetylcysteine, bleeding has been very rarely reported, which was most often associated with the development of hypersensitivity reactions.
There have been cases of a decrease in platelet aggregation, but there is no clinical confirmation of this.
Very rarely Quincke's edema, facial edema, cases of anemia, hemorrhage, anaphylactic reactions or even shock have been reported.

Contraindications:

Hypersensitivity to acetylcysteine ​​and excipients;
- peptic ulcer;
- hereditary fructose intolerance;
- pulmonary bleeding or hemoptysis;
- in pediatric practice - with hepatitis and renal failure (the threat of accumulation of nitrogen-containing products).

Use ACC with caution with peptic ulcer of the stomach or duodenum.
When preparing a solution, a patient with bronchial asthma can inhale air with particles of the drug, which causes irritation of the mucous membrane of the upper respiratory tract and can provoke reflex bronchospasm.
For the best mucolytic effect in the treatment with acetylcysteine, you should drink plenty of fluids.
10 ml of the prepared oral solution contains 0.31 carbohydrate units, which should be taken into account for patients with diabetes.
Sorbitol has a slight laxative effect on the stool.

Newborns and children under 1 year of age acetylcysteine ​​is used exclusively for health reasons under strict medical supervision. The recommended dosage (10 mg/kg body weight) must not be changed.
ACC 200 is not used at the age of up to 2 years.
ACC Long is not recommended for children under 14 years of age.
Responsiveness when driving and working with machinery does not change when taking acetylcysteine.

Interaction
other medicinal
by other means:

Tetracycline and its derivatives (except doxycycline) should not be used together with ACC in pediatrics.
During experimental in vitro studies, there were no cases of inactivation of other types of antibacterial drugs.
Nevertheless, it is recommended to observe the interval between taking ACC and antibiotic at 2 o'clock (at least).
In vitro, the incompatibility of acetylcysteine ​​with semi-synthetic penicillins, aminoglycoside and cephalosporin antibiotics has been proven. Such studies have not been conducted with erythromycin, amoxicillin and cefuroxime.
Simultaneous use of antitussive drugs can lead to stagnation of the secretion of the respiratory tract.
The use of nitroglycerin may enhance the vasodilating effect of the latter.

Pregnancy:

There is no embryotoxic effect in acetylcysteine, however, during pregnancy, as well as during breastfeeding, it is prescribed only if there are indications under the supervision of a physician.

Overdose:

There are no data on cases of overdose of dosage forms of acetylcysteine ​​intended for oral administration.
Acetylcysteine, when taken at a dose of 500 mg / kg / day, does not cause signs and symptoms of an overdose.
Symptoms: Overdose may present with gastrointestinal symptoms such as nausea, vomiting and diarrhoea.
Treatment: there is no specific antidote for acetylcysteine ​​poisoning, symptomatic therapy.

Release form:

ACC 100, 200 - effervescent tablets 20 pcs.
ACC hot drink - hot drink powder for internal use- 200 mg (20 sachets) and 600 mg (6 sachets).
ACC-long - effervescent tablets (600 mg), 10 pcs. in a tube.

ACC powder for solution for oral administration - 100, 200 mg, 2 pcs. packaged.
ACC for children - powder for the preparation of a solution for oral administration 30 g in a 75 ml vial (20 mg / ml) and 60 g in a 150 ml vial (20 mg / ml).

Storage conditions:

In places inaccessible to children.
Temperature not more than 30°С.
The finished solution should be stored for no more than 12 days in the refrigerator (at a temperature of 2-8°C).

1 sachet (100 mg) ACC granules for oral solution (orange) contains:

- excipients: ascorbic acid, sucrose, saccharin, orange flavor.

1 effervescent tablet (100 mg) ACC contains:
- active ingredient: acetylcysteine ​​- 100 mg;
- excipients: citric acid anhydride - 679.85 mg, sodium bicarbonate - 291 mg, mannitol - 65 mg, ascorbic acid - 12.5 mg, lactose anhydride - 75 mg, sodium citrate - 0.65 mg, saccharin - 6 mg, blackberry flavor "B" - 20 mg.

For the treatment of coughing fits with sputum that does not come out well, ACC is used. With the help of this medicine, even pus can be thinned. Produced in various forms. It is worth studying in detail how ACC is used for coughing, the instructions for using the drug give precise instructions on how to dose the medicine.

Composition and properties

ACC, or ACC, is a drug with mucolytic and expectorant properties. Thanks to its use, liquefaction and accelerated discharge of viscous mucus occurs. This drug is used as a therapeutic agent for diseases of the respiratory system. What kind of cough is it used for? The medicine is effective for wet cough.

Medicines of the ACC series are produced by the Slovenian company Sandoz or the German company Hexal AG. Any of them can be purchased at a pharmacy without a doctor's prescription.

• effervescent tablets 100 mg, 200 mg, 600 mg;
• disposable bags with granules (powder);
• syrup for children;
• injection.

Effervescent tablets are white, round and flat. They dissolve very quickly in water. It turns out a clear drink. Children are treated with 100 mg tablets, and adults use 600 mg effervescent preparations. A carton usually contains 10 pieces.

The composition of effervescent products includes the main active ingredient - acetylcysteine ​​​​and excipients. Most acetylcysteine ​​is contained in 600 mg tablets, which is why they are called ACC Long.

Granules or powder for preparing a warm drink are in disposable bags. The weight of one package is only 3 g. The powder is dissolved in warm water and a drink with the taste of lemon, orange or honey is obtained. The standard package contains 6 or 20 sachets.

The syrup is mainly used to treat children, but adults can also use it if desired. 1 ml contains 20 mg of the active substance. The medicine is a viscous thick liquid with a cherry flavor. Does not contain ethyl alcohol and dyes. The syrup includes additional components - caramellose, cherry flavor, saccharinate, methyl parahydroxybenzoate, disodium edetate. In pharmacies, it is sold in dark glass bottles of 100 or 200 ml. The kit includes a 10 ml measuring cap and a 5 ml syringe.

ACC injection solution is used for inhalation or intravenously. The active substance is acetylcysteine. Transparent colorless liquid is in ampoules, in one package 5 pieces of 300 mg. The drug is used in intensive care units only if the use of tablets is not possible.

pharmachologic effect

Acetylcysteine ​​has antioxidant and pneumoprotective properties, acts as an antidote for acute paracetamol poisoning, as well as aldehydes and phenols. When taken orally, it is completely absorbed, and after 1-3 hours, the maximum concentration of the active component in the blood is observed. It is excreted from the body with urine and feces. The drug passes through the placenta, which can accumulate in the amniotic fluid.

Indications

The drug is effective in diseases of the respiratory system, when a viscous, hard-to-remove mucus is formed. ASS differs from other mucolytics in its high efficiency. The drug directly affects the sputum that has already formed, dilutes it.

The main purpose of using ACC is to reduce the viscosity of sputum. Apply it if the patient has a thick cough, and sputum does not come out well. With bronchitis, nocturnal cough decreases. True, after 18 hours the medicine can not be given. If ACC cough is taken right before bedtime, the mucus will thin out, which will cause coughing fits.

With rhinopharyngitis, the medicine will not save the patient from sputum. Viscosity may decrease, but mucus production in the nasopharynx will not stop. In this case, complex treatment is needed. ACC is used for infectious and non-infectious diseases of the bronchopulmonary system.

It is advisable to use when:

• bronchitis;
• cystic fibrosis;
• bronchial asthma;
• inflammation of the lungs;
• otitis;
• sinusitis;
• bronchiectasis;
• bronchiolitis.

Important! ACC is prescribed as a cough suppressant only when there is already mucus in the bronchi.

Instructions for use

Doses of the drug depend on the form of release and the amount of the main active ingredient. Adults and children are prescribed a different amount of medication. The instructions that are available in each package for the drug help determine the dosage.

How to use for adults:

• effervescent preparations: ACC 200 three times a day, ACC 600, like ACC Long, once a day;
• granules (powder): one sachet (200 mg) or 2 sachets (100 mg) three times a day;
• syrup: 10 ml three times a day.

More than 600 mg of the drug should not be used per day. It should be treated with the drug for one week.

Dosage for children:

• syrup: from 2 to 5 years, 5 ml - 2-3 times a day, and from 6 to 14 years, 5 ml three times or 10 ml twice a day;
• effervescent preparations: from 2 to 5 years, one tablet (ACC 100) 2 or 3 times a day, and from 6 to 14 years, one tablet (200 mg) twice or one tablet (100 mg) three times a day;
• granules (powder): from 2 to 5 years one sachet (100 mg) - 2 or 3 times a day, and from 6 to 14 years one sachet (200 mg) 2 times or one sachet (100 mg) three times a day.

At what age should children be given syrup? You can treat a baby with this remedy from 2 years old.

The duration of treatment for children is no more than 5 days. The maximum effect of taking the drug occurs on the 3rd day. The final dose is prescribed only by the pediatrician. Take ACC for children after meals. Additionally, it is recommended to drink plenty of fluids (herbal tea, juice, dried fruit compote). It is better for a child to give syrup, and if he does not like the taste of cherries, you can give powder, it resembles an orange.

How to use

Effervescent preparations are dissolved in warm water. The solution is prepared immediately before use. For 100 mg of the drug you need 100 ml of liquid. Granules (ACC powder) are dissolved in warm water. To do this, take a glass of liquid and pour a bag of medicine into it, mix everything and drink it. The glass must be made of glass, you can not use metal utensils.

The syrup is drawn into a measuring syringe, not directed into the throat, but into the buccal region, otherwise the baby may choke. You can only draw medicine with a syringe, and then pour it into a spoon and thus give it to the child. Syrup is not mixed with water, but it can be washed down with tea or juice.

Important! Children under 2 years of age are not prescribed medication. The dosage for such babies is not indicated in the instructions, since there are a number of contraindications. If you give a medicine to a child under 2 years old without instructions from a pediatrician, then he may experience suffocation.

Overdose

Exceeding the daily dose of the drug does not cause intoxication. However, in case of an overdose, the patient may experience nausea, sometimes even vomiting, and gastrointestinal upset. Antidote in this case is not needed, symptomatic treatment.

Contraindications

ACC does not apply:

• with an ulcer;
• with hepatitis;
• during pregnancy and during lactation;
• children under 2 years old;
• with liver failure;
• if there is hypersensitivity to the active ingredient;
• with bleeding from the lungs;
• if you have fructose intolerance.

Important! Care should be taken to prescribe the drug to patients with bronchial asthma, it is necessary to ensure that bronchospasm does not occur. People with diabetes should take into account that the drug contains sucrose. ACC Long is prescribed only for children who are 14 years old.

Adverse reactions

ACC and adverse reactions:

• nausea;
• stomatitis;
• vomit;
• gastrointestinal problems;
• hives;
• noise in ears;
• bronchospasm;
• headache;

There may also be problems with the cardiovascular system in the form of increased blood pressure and arrhythmias.

Interaction with other drugs

ACC should not be used in conjunction with cough suppressants. If you inhibit the reflex contraction of the bronchi, this can lead to stagnation of mucus in them. It should not be used with oral antibiotics. The interaction of these drugs leads to a decrease in the effectiveness of both. An interval of 2 hours should be maintained between doses. True, there are exceptions to this rule: the antibiotics Loracarbef and Cefixime.

Analogues

ACC costs from 150 to 650 rubles, depending on the type. So, for example, the price of syrup for children is 300 rubles, Long effervescent preparations cost 500 rubles, and sachets - 150 rubles. If ACC is not suitable for some reason, other cough medicines for children can be purchased - for example, Bromhexine. It costs about 170 rubles. The medicine does an excellent job with coughing, and its list of contraindications is much smaller. There are other analogues in syrups: Lazolvan, Flavamed, Ambrobene.

Ascoril can be used to treat cough. The drug relieves spasms in the bronchi, has a strong mucolytic effect. Fluimucil can also be used as a drug that thins sputum in the bronchi.

Acetylcystine is a domestic analogue of ACC. It has the same effect, but costs about 130 rubles. The drug is produced in the form of granules, powders and in the form of effervescent tablets. In addition, ACC analogs are: Acestine, Mukobene, Mukomist. The selection of an analogue is carried out by a doctor.

ACC is suitable if you need to cope with sputum that is already in the bronchi. The medicine is used to treat both adults and children. Use it only as directed by a doctor, although it can be bought at a pharmacy without a prescription. Self-medication is not worth it, because you need to correctly determine the nature of the cough.

Respiratory system diseases are the most common diseases registered in medical institutions.

Diseases can be caused by infection: bacteria, viruses, fungi, provoking inflammatory processes.

ACC is a mucolytic agent that can eliminate the cause of the disease and its symptoms.

Indications for use

ACC is prescribed for accumulation of sputum with a viscous and thick consistency in the bronchi or upper respiratory tract and has an expectorant, mucolytic, anti-inflammatory and antitussive effect.

ACC is prescribed in the presence of diseases:

• acute chronic bronchitis;
• tracheitis;
• bronchiolitis;
• bronchiectasis;
• bronchial asthma;
• lung abscess;
• emphysema;
• cystic fibrosis;
• average exudative otitis;
• pneumonia.

Way

Maximum daily requirement in the treatment of diseases other than cystic fibrosis:

• for children from 2 to 5 years - 200 - 300 mg (in three divided doses);
• for children from 6 years old - 300 - 400 mg (in two divided doses);
• for adults and children from 14 years of age - 400 - 600 mg.

If the disease passes in an acute form and has no complications, then treatment with the drug lasts about seven days.

In difficult cases, treatment is carried out in courses that can take up to six months.

Maximum daily requirement in the treatment of cystic fibrosis:

• for children from 10 days from birth to 2 years of age - 50 mg (in 2-3 doses);
• for children from 2 to 5 years old - 400 mg (in four divided doses);
• for children from 6 years old - 600 mg (in three divided doses);
• for adults and children from 14 years of age - up to 800 mg.

The course of treatment for cystic fibrosis can last from three to six months.

The drug ACC should be taken after meals.

The granulated powder or tablet is dissolved in any liquid (in 100 g of water, juice of cold drinks).

The mucolytic property of the drug is enhanced with additional fluid intake.

A solution of effervescent tablets should be used no later than two hours.

ACC medicine is produced:

• ACC100, ACC200, ACC-long. The active substance is acetylcysteine. Additional substances: anhydrous citric acid, anhydrous sodium carbonate, sodium bicarbonate, ascorbic acid, mannitol, anhydrous lactose, sodium saccharinate, sodium citrate, flavor (blackberry);
• ACC hot drink, ACC, ACC for children. The active substance is acetylcysteine. Additional substances: ascorbic acid, sucrose, sodium saccharinate, flavor (lemon, honey).

Interaction with other drugs

Co-administration with drugs that have a negative effect:

• antitussives. When suppressing a cough, there is a possibility of accumulation and stagnation of sputum;
• nitroglycerin. The vasodilating effect of nitroglycerin when interacting with ACC may increase;
• antibiotics. Decreased antibacterial activity. It is recommended to take ACC with antibiotics at least two hours apart (exceptions are Loracarben and Cefixime);
• paracetamol. Acetylcysteine ​​may reduce its hepatotoxic effect.

The preparation of the ACC solution must be carried out in glassware. Contact of the drug with metal or rubber contributes to the formation of sulfides, accompanied by a characteristic odor.

Side effects

Adverse reactions may occur with intolerance or allergy to the components of the drug.

After taking ACC, the following reactions may occur:

• from the immune system: urticaria, rash, itching, eczema, angioedema;
• from the cardiovascular system: hypertension, tachycardia;
• on the part of the respiratory system: bronchospasm (with a hyperreactive bronchial system), shortness of breath, rhinorrhea;
• on the part of the hearing organs: in rare cases, ringing in the ears;
• from the side of the central nervous system: sometimes headache;
• from the gastrointestinal tract: heartburn, nausea, diarrhea, pain in the abdomen.

Quite often there is a feverish state. Quincke's edema, anemia, Stevens-Johnson syndrome, Lyell's syndrome, facial edema, anaphylactic shock have been observed in rare cases. Sometimes platelet aggregation may decrease, however, this fact has no clinical confirmation.

Reactions may occur with an overdose. In such cases, nausea, migraine, diarrhea, dizziness may occur.

Contraindications

General contraindications:

• bleeding in the lungs;
• ulcer of the stomach and small intestine during the period of exacerbation;
• intolerance to acetylcysteine ​​or components of the drug;
• cough with bloody secretions.

Take with caution:

• with a stomach ulcer and small intestine (in history);
• with varicose veins of the esophagus;
• with obstructive bronchitis;
• with histamine intolerance (long-term use of ACC can provoke side effects);
• with bronchial asthma;
• with renal failure;
• with violations in the work of the adrenal glands;
• with liver failure.

Contraindications to the use of effervescent tablets:

• glucose-galactose malabsorption;
• lactose intolerance;
• age less than two years;
• lack of lactase.

Contraindications to the use of a solution of granular powder:

• sensitivity to fructose;
• age less than six years or less than two years - with orange flavor;
• sucrose deficiency;
• isomaltase deficiency.

Pregnancy and lactation

Pregnant women and during breastfeeding, the drug ACC in any form is contraindicated. With the ratio of benefit to the mother and the threat to the child, the drug is prescribed to the mother, provided that breastfeeding is refused.

Terms and conditions of storage

Store the drug ACC should be in a dark place inaccessible to children, not higher than +30°C.

The shelf life of the drug is not more than three years.

Do not use ACC in any form later than the period indicated on the package.

The tube with tablets should be tightly closed.

Price

In Russia, the average price of the drug is:

• ACC - from 230 rubles
• ACC100 - from 240 rubles;
• ACC200 - from 290 rubles;
• ACC hot drink - from 136 rubles;
• ACC-long - from 327 rubles;
• ACC for children - from 250 rubles.

In Ukraine, the average price of the drug is:

• ACC - from 113 hryvnia;
• ACC100 - from 112 hryvnia;
• ACC200 - from 180 hryvnia;
• ACC hot drink — from UAH 53;
• ACC-long — from UAH 139;
• ACC for children - from 156 hryvnia.

Analogues

In case of sensitivity to the components of the drug, the appearance of adverse reactions to ACC, you can use similar drugs, such as:

• Acestine;
• Mukobene;
• Fluimucil;
• Mukomist;

Lung problems are often accompanied by a severe cough that can be painful. Effervescent tablets or ACC powder will help get rid of a cough. This is a universal remedy that is produced for both children and adults. The drug can be taken during pregnancy, rheumatoid arthritis, bronchitis, tracheitis, influenza, pneumonia. Pharmacology offers many cough remedies, including Russian fluimucil, lazolvan, ambroxol, bromhexine, ascoril, antibiotics, ambrobene, mukaltin, codelac broncho, erespal and others. However, the best drug is considered to be acc. It can be taken for both dry and wet coughs. Wikipedia defines the drug as an effective expectorant with a detoxifying effect. The international name sounds like Acetylcysteine ​​(in Latin Acetylcysteine).

ACC composition, active substance

The active substance in the composition of the drug according to INN is acetylcysteine, which is a derivative of the amino acid cysteine. The drug breaks the bisulfide bonds of sputum mucopolysaccharides, due to which it has an expectorant effect. The drug has an antioxidant effect and blocks the development of pneumonia. According to its characteristics, it is an antidote that can be used for aldehyde poisoning.

Indications for use

The drug is prescribed for any diseases that are associated with the formation of sputum in the tracheal tract. The medicine should be used for bronchial asthma, sinusitis, laryngitis, otitis media, cystic fibrosis, bronchitis at various stages and other ailments. The medicine is usually available in sachets and is taken by prescription. Although the form of release may be different. The powder must be dissolved in water. It is desirable to make a hot drink from the granules.

With what kind of cough does it help: with dry, wet?

Annotation to the drug informs that it is prescribed to thin sputum in order to facilitate its removal from the respiratory tract. However, the cough may be dry or wet. Moreover, the first type often occurs with colds or allergies. It should be noted that ACC does an excellent job both with the withdrawal of sputum and with the elimination of dry cough. The medicine can be used for sinusitis. Drugs are cheaper available in Ukraine. During a cold from a dry cough, inhalation will be useful along with the medicine.

ACC instructions for use

ACC 200 instructions for use provides detailed information on dosage, indications and contraindications. Taking pills for cystic fibrosis should be carried out in the following dosage: for patients weighing more than thirty kilograms, eight hundred milligrams per day are prescribed. For a child aged ten days to two years, the doses will be 50 mg three times a day. The course of treatment can be from three to six months.

Powder for adults how to drink, norm

And now about how to breed for adults. To prepare the solution, you must use 100 mg or half a sachet. The content is diluted in water or iced tea and taken immediately after a meal. The drug in the form of granules is dissolved in a glass of hot water and drunk without waiting for cooling.

Long, dosage

ACC long instructions for use of effervescent tablets recommend the following dosage. Adults and adolescents from the age of fourteen take 600 mg (one tablet) per day. If there is a seasonal cold, then the drug lasts for five to seven days. In other cases, the duration is prescribed by the doctor. Tablets should be taken after a meal.

How to take effervescent tablets?

The drug in this form should be taken immediately after dissolution. In some cases, the prepared solution can be left for two hours. With additional water intake, the remedy gives a stronger expectorant effect. People from the age of fourteen are prescribed 20 mg three times a day.

Syrup for children

Syrup for children is prepared from granules of 100 and 200 mg. Children from six to 14 years of age should drink a syrup prepared from 100 mg three times a day. Children from two to five years old take the same dosage, but twice a day.

Can be taken during pregnancy?

There are not enough statistical data on intake among pregnant women, mothers during lactation and breastfeeding to draw unambiguous conclusions about the benefits or harms of the drug. In this regard, the manufacturer recommends taking the medicine in any trimester only if the expected benefit will exceed the possible risk to the child or fetus.