Galazolin indications for use. Eye drops galazolin. Registration certificate holder

The off-season periods are insidious in their weather instability. And along with temperature fluctuations and drafts, their indispensable companion, acute rhinitis, often steps. So now, we finally waited for spring warming, hot sunshine and a gentle, but still cool, breeze.

People unbuttoned their jackets, took off their hats, threw open the windows and ... sneezed, coughed and grabbed their little noses.

With a cold, everyone struggles in their own way. Someone lets everything take its course - in a week, they say, it will pass by itself. Someone immediately runs to the pharmacy for drops, gels, pills and other "lifeline" from symptoms of ARI.

But, alas, both approaches can lead to serious complications. Medical practice has proven more than once that untimely treatment and self-medication can transform an ordinary flow from the nose into sinusitis. No need to completely believe in advertising and seek advice from friends: take the time and go to a specialist.

Drops "Galazolin"

No treatment for the common cold can do without vasoconstrictors. But let's say right away that these drugs do not cure, but only alleviate the patient's condition.

"Galazolin" - inexpensive, fairly effective vasoconstrictor nasal drops with an anticongestive effect. They allow you to quickly get rid of nasal congestion. However, like all drugs, they should not be abused. In ENT practice, they are used exclusively for local use and symptomatic treatment.

Getting on the nasal mucosa, the drug quickly eliminates the swelling of the nose and nasopharynx, provoking a natural decrease from the mucous membranes of the blood. The package leaflet for use notes that already in the first minutes after use, breathing becomes easier, as the nasal passages and sinus openings expand to normal sizes.

The full effect of "Galazolin" develops within 10 minutes after use and the medicine lasts about 6-8 hours. With short-term use, the drug does not cause irritation, but with prolonged use it can provoke swelling of the mucous membrane in the form of nasal congestion.

The active substance of this drug is xylometazoline hydrochloride. The drug is available in the form of a dosed nasal spray and an undosed spray with menthol and eucalyptus, nasal aerosol and gel, in the form of drops.

A runny nose is a vile symptom that overcomes not only adults, but also kids. Snot in children is not just "bad", but dangerous. Therefore, many parents are interested in the question, is Galazolin allowed for children? For such cases, pharmacists have developed a special drug - "Galazolin" for children. This drug is prescribed by a pediatrician from a certain age and is used in a strict dosage and for a short time.

These are 0.05% nasal drops that cause fewer allergic reactions and can be used by children from two years of age. For this reason, they can be used by pregnant women and nursing mothers, but only in cases of emergency.

However, some pediatricians oppose this remedy for children. They believe that on the modern pharmacological market there are a large number of other absolutely safe drugs that are approved for use from the first days of a baby's life. Undoubtedly, there is some truth in this, and choosing an imported analogue will not be a problem, but the price tag on it will be appropriate.

"Galazolin" will help out a lot if it is not possible to purchase expensive medicines, and a small patient needs prompt assistance.

After all, difficulty in breathing in a child is a problem that requires a professional solution and a quick response.

Indications for use

All forms of release of the drug, including "Galazolin" drops, are prescribed for the rapid removal of edema of the nasopharyngeal mucosa.

The package insert notes that the remedy is effective:

with bacterial, viral and allergic rhinitis;
with inflammation of the sinuses;
with otitis;
with eustachitis;
with sinusitis, frontal sinusitis and other forms of sinusitis;
with seasonal allergic rhinoconjunctivitis.

Also, "Galazolin" is successfully used in preparation for diagnostic procedures of the nasal passages.

However, you should not abuse this drug: it can be addictive and stop having the proper effect. For this reason, doctors strongly recommend stopping the use of Galazolin as soon as the runny nose begins to disappear.

Side effects of the drug and contraindications to its use

Like all medicines, Galazolin drops can cause side effects and have contraindications. Every person should know about these precautions so as not to harm their own health. The instruction to "Galazolin" informs about all kinds of adverse reactions.

Be careful, the use of "Galazolin" is contraindicated for use:

with increased sensitivity to xylometazoline hydrochloride;
with vasomotor and chronic rhinitis;
with increased eye pressure;
with atrophic rhinitis;
with tachycardia;
with high blood pressure;
in violation of the work of the adrenal glands;
with atherosclerosis;
with angle-closure glaucoma;
with pheochromocytoma;
with endocrine diseases such as diabetes and hyperthyroidism.

The use of drops is prohibited simultaneously with antidepressants, which are used for alcoholism, depression and in case of Parkinson's disease, and within a half month from the date of the last intake of these medications.

In the list of side effects in the instructions, sneezing, burning and dryness in the nose are noted. This is especially true for "Galazolin" for children, since the mucous membranes in children are much more sensitive and tender than in adults. It happens that patients complain of "congestion" of the nose, similar to the common cold in the initial stage.

Due to an overdose of the drug, blood pressure may increase and the pulse becomes more frequent. Insomnia, anxiety, headaches and nausea are possible, but this, as practice shows, is isolated cases.

Dosage and method of application

"Galazolin" is an excellent economical remedy for the treatment of all kinds of rhinitis, sinusitis in children and adults. But it should be remembered that this drug should not be abused and used without the recommendation of a doctor more than three times a day and more than a two-week course of administration. An acceptable course of treatment is designed for three to five days using drops 2-3 times a day.

Methods of application of the drug and dosage vary depending on the form of release of the nasal agent, as well as on the age category of patients.

Gel Galazolin nasal - xylometazoline hydrochloride , sodium chloride, sodium dihydrogen phosphate, sodium hydrogen phosphate, benzalkonium chloride, hydroxyethylcellulose, ethylenediaminetetraacetic acid salt, glycerol, purified water.

Nasal drops Galazolin - xylometazoline hydrochloride , sodium hydrogen phosphate, , disodium edetate, benzalkonium chloride, sorbitol, sodium dihydrogen phosphate monohydrate, purified water.

Release form

Nasal gel 0.05% and 0.1% is a colorless, transparent thick liquid in a polyethylene bottle with an applicator and dispenser 10 g in a carton.
Nasal drops 0.05% (Galazolin for children) and 1% - a colorless, transparent liquid in a 10 ml polyethylene bottle with a built-in dropper in a carton.

pharmachologic effect

Vasoconstrictor, alpha-adrenomimetic, anticongestive.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The active substance of the drug is a derivative imidazoline . Affects adrenoreceptors blood vessels located in the mucosa of the nasopharynx. Under the influence of the drug, blood vessels narrow, hyperemia and as a result, the swelling of the mucous membrane and the amount of discharge from the nose decrease. This helps to facilitate the process of nasal breathing in various diseases (diseases of the paranasal sinuses, allergic conditions). The effect is observed after 10-20 minutes and lasts for 10 hours.

Pharmacokinetics

Indications for use

rhinitis viral, bacterial, allergic, traumatic etiology;
(average), eustachitis ;
(to improve secret evacuation);
when carrying out diagnostic manipulations in the nasal passages.

Contraindications

High sensitivity to the drug, atrophic, (for nasal drops), arterial hypertension , age up to 6 years (drops 0.1%) and up to 2 years (drops 0.05%), age up to 12 years (gel 0.1%) and up to 3 years (gel 0.05%).

Take the drug with caution at, during the period lactation , III-IV class.

Side effects

Rarely observed, manifested by local reactions of the nasal mucosa (irritation, burning, dryness, sneezing). In case of improper use of the drug (swallowing) -, sedation .

Application instruction of Galazolin (Way and dosage)

Adults Galazolin in the form of a gel is prescribed intranasally, 1 spray in each nostril after 8-10 hours. The course of the drug is not more than 5 days.

According to the instructions for use, Galazolin drops are prescribed for adults intranasally in each nostril, 2-3 drops every 8-10 hours.

Children's Galazolin in the form of 0.05% drops is prescribed at the age of 2-6 years twice a day, 1-2 drops in each nostril. Older than six years, instill up to three times a day a 0.1% solution of 2-3 drops.

In the form of a 0.05% gel for children 3-6 years old - in each nostril, 1 dose twice a day. At the age of 12 years, apply 0.1% gel 3 times a day.

Overdose

If improperly used in children and swallowing the drug or taking too large a dose, a pronounced sedative effect may occur, manifested drowsiness , nausea, dilated pupils, vomiting , tachycardia , respiratory failure, mental disorders, pulmonary edema , respiratory depression.

Interaction

The drug should not be taken with antidepressants And MAO inhibitors .

Terms of sale

Non-prescription leave.

Storage conditions

At a temperature not exceeding 25°C.

Best before date

Galazolin during pregnancy

The use of the drug during pregnancy is contraindicated. Reliable information about the selection xylometazoline there is no mother's milk, therefore, during lactation, it is necessary to prescribe the drug with caution.

Analogues

Coincidence in the ATX code of the 4th level:

It should be noted that it is relatively difficult to dose Galazolin in drops, part of the solution can get into the throat, so the risk of side effects is higher. Many patients note adverse reactions:, anxiety . Also, they often forget about the short-term use of the drug and use it more than the time indicated in the instructions.

This contributes to the development, in which vasoconstriction is replaced by an increased supply of mucous blood and the resumption of discharge or nasal congestion, which is difficult to treat. With prolonged use of the drug develops atrophy of the nasal mucosa .

Galazolin's price, where to buy

The price of Galazolin (nasal drops 0.05%) varies between 30-32 rubles per pack; 0.1% - 36-38 rubles; Nasal gel 0.05% - 123-126; 0.1% - 162 -168 rubles per pack.

You can buy the drug in any form without difficulty in the pharmacy network of Moscow and other cities.

Internet pharmacies in Russia Russia
Internet pharmacies in Ukraine Ukraine
Internet pharmacies in Kazakhstan Kazakhstan

ZdravCity

Galazolin drops called. 0.05% 10ml n1 Polfa Warsaw

Galazolin drops called. 0.1% 10ml n1 Polfa Warsaw

Pharmacy Dialog

Galazolin (fl-cap. 0.05% 10ml)

Galazolin (fl-cap. 0.1% 10ml)

Europharm * 4% discount with promo code medical11

Galazolin nasal drops 0.1% 10 ml

Galazolin nasal drops 0.05% 10 mlPolfa, Warsaw Pharmaceutical Factory

Pharmacy24

Galazolin 0.1% 10ml №1 nasal gelMedana Pharma Joint Stock Company, Poland

Galazolin is a nasal vasoconstrictor used topically in ENT practice. The active substance is Xylometazoline.

Alpha adrenostimulator, narrows the blood vessels of the nasal mucosa, eliminating swelling and hyperemia of the mucous membrane. Facilitates nasal breathing in rhinitis.

The drug is prescribed for instillation into the nose, has a vasoconstrictive effect, reduces swelling, reduces hyperemia and reduces exudation.

The action of Galazolin nose drops occurs after a few minutes and lasts for several hours.

The most common form of release are nasal drops with different dosages of the active substance. They also produce nasal gel, metered and non-metered spray and Galazolin aerosol.

Drops in the nose are addictive, so when the runny nose decreases, you should stop using them. The optimal course of therapy is 3-5 days, during which the drug can be used no more than 3 times a day.

Indications for use

What helps Galazolin? According to the instructions, nose drops are prescribed in the following cases:

Acute rhinitis of viral or bacterial origin;
allergic rhinitis;
Acute sinusitis;
Chronic sinusitis in the acute phase;
Pollinosis;
Otitis media (in order to reduce swelling of the mucous membrane of the nasopharynx and restore the patency of the Eustachian tube).

Instructions for use Galazolin, dosage drops

The use of the drug depends on the form of release and dosage of the active substance. Recommended dosage instructions for use:

Drops of Galazolin 0.1% for adults and children over 12 years old - from 2 to 3 drops in each nasal passage. Instillation is carried out every 8-10 hours.
Children's Galazolin (0.5%) in the form of drops - 1 drop for children from 4 months to two years, 2-3 drops for children from 2 to 12 years (every 8-10 hours).
Nasal gel 0.05% for children aged 3-12 years - 1 pump in each nasal passage every 8-10 hours.
Nasal gel 0.1% for adults and children over the age of 12 - 1 pump in each nasal passage every 8-10 hours.

The course of treatment is 3-5 days and in any case should not exceed 10 days. Do not use the drug more than 3 times a day.

special instructions

Long-term use and overdose should be avoided (weakening of action and the likelihood of mucosal atrophy and reactive hyperemia with drug-induced rhinitis).

It should not be taken simultaneously with MAO inhibitors and within two weeks from the last dose of these drugs.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Galazolin drops:

Irritation and / or dryness of the mucous membrane of the nasopharynx;
Burning and paresthesia of the nasal mucosa;
Sneeze;
Hypersecretion of the mucous membrane of the nasal cavity;
swelling of the nasal mucosa;
palpitations;
Tachycardia;
Arrhythmia;
Increased blood pressure;
Headache;
Vomit;
Insomnia;
visual impairment;
Depression.

Contraindications

Galazolin is contraindicated in the following cases:

atrophic rhinitis;
Angle-closure glaucoma;
Increased intracranial pressure;
Severe atherosclerosis;
Hyperthyroidism;
Arterial hypertension;
Diabetes;
Tachycardia;
Individual sensitivity to the active substance or other components of the drug;
Pheochromocytoma.

According to strict indications, it is possible to use the drug during pregnancy and lactation.

Overdose

Significant overdose or accidental ingestion, especially in children, may cause sedation, visual disturbances, headache, irritability, heart rhythm disturbances, and insomnia.

Long-term use may lead to the development of secondary drug-resistant rhinitis resistant to therapy.

Treatment is symptomatic.

Galazolin analogues, price in pharmacies

If necessary, Galazolin drops can be replaced with an analogue for the active substance - these are drugs:

(from 12.00 rubles),
Rhinorus (from 16.00 rubles),

Galazolin belongs to the group of vasoconstrictor and anticongestive drugs - non-selective alpha-agonists and is used as a symptomatic drug for topical use in inflammatory and allergic diseases of the mucous membrane of the nasal cavity and paranasal sinuses. In this article, you can read the instructions for using the drug Galazolin, consider the composition and possible contraindications for instillation into the nose.

Composition and form of release

Galazolin (Galazolin) narrows the vessels of the nasal mucosa, reduces hyperemia, swelling and the amount of discharge. The action occurs in 5-10 minutes and lasts for 5-6 hours (vasoconstriction lasts up to 8-12 hours). In its structure and action, it is closest to naphthyzinum.

The effect of the medicine lasts about six hours. With a single use, the drug does not have an irritating effect, but with prolonged use it can provoke the opposite effect.

Indications for use

In what cases does Galazolin help with a runny nose, and under what conditions is it better to refuse to use it?

Indications for the use of Galazolin nasal drops are:

runny nose of various etiologies (with viral, bacterial or viral-bacterial infections of the nasal cavity),
caused by an exacerbation of a chronic process,
allergic process,
localized in the nasal cavity (hay fever) and when one's own pathogenic microflora is activated (with a decrease in immunity or layering).

It is also prescribed as an aid in:

acute otitis media,
eustachitis,
(, ethmoiditis and) together with antibacterial, anti-inflammatory and mucolytic drugs.

It is used in ENT practice only for short-term symptomatic treatment and topical application (see instructions for Galazolin).

Contraindications

Nasal drops from this group of drugs are prohibited from prescribing to patients if they have the following conditions:

hypersensitivity to components;
atrophic rhinitis;
angle-closure glaucoma;
arterial;
severe atherosclerosis;
tachycardia;
hyperthyroidism (for nasal drops);
surgical intervention on the meninges (in history);
simultaneous reception of MAO inhibitors and a period of 14 days after the end of their use;
concomitant use of tricyclic antidepressants;
pregnancy;
children's age up to 6 years (for 0.1% nasal drops) and up to 2 years (for 0.05% nasal drops);
children's age up to 12 years (for 0.1% nasal gel) and up to 3 years (for 0.05% nasal gel).

Galazolin during pregnancy: the drug should be used only after assessing the risk-benefit ratio for the fetus and mother. It is not allowed to exceed the recommended doses during pregnancy and lactation (breastfeeding).

With caution, the drug should be used during lactation, with diabetes mellitus, with angina III-IV functional class, prostatic hyperplasia, pheochromocytoma (for nasal drops), with hyperthyroidism (for nasal gel).

Instructions for use

Galazolin drops 0.1% for adults and children over 12 years of age are prescribed in the amount of 2-3 drops in each nasal passage. Instillation should be carried out every 8-10 hours. The duration of the course of treatment should not exceed 3-5 days, since the active substance of the drug can be addictive. If during the period of therapy the patient does not improve, then you should consult a doctor again to select another drug or clarify the adequacy of the diagnosis.

Galazolin nose drops for children (0.5%) are instilled at the same frequency as for adults: 1 drop for children from 4 months to two years; 2-3 drops for children from 2 to 12 years.

Before use, clean the nasal passages. The action comes in a few minutes and lasts for several hours.

Side effects for the body

The instruction to Galazolin warns of such possible adverse reactions as dryness of the nasal mucosa, burning, sneezing, and a feeling of nasal congestion.

Local overdose can provoke:

high blood pressure,
tachycardia,
fatigue,
anxiety,
nausea,
headache.

With prolonged use of nasal drops, the patient may develop drug-induced rhinitis.

Overdose

Symptoms: increased side effects.

Interaction with other drugs

The drug should not be taken with antidepressants and MAO inhibitors.

Best before date

Galazolin is available in pharmacies without a doctor's prescription. The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C. Best before date:

nasal gel 0.05% and 0.1% - 3 years.
nasal drops 0.05% and 0.1% - 4 years.

Do not use Galazolin after the expiration date indicated on the package and in the instructions for the drug.

Analogues

In pharmacies, you can find drugs that are similar in their therapeutic effect to Galazolin nasal drops. These analogues include:

Naphthyzin;
Farmazolin;
Rinazolin;
Nazivin;
Nazivin baby;
Otrivin.

Prices in pharmacies

In Russia, Galazolin can be purchased at the following prices: 10 ml bottle of Galazolin drops 0.05% produced by the Warsaw Pharmaceutical Plant - 35-38 rubles (15 hryvnias), 0.1% drops - 38-42 rubles (15-17 hryvnias). Gel 0.05% - 122-146 rubles (49-59 hryvnia), gel 0.1% - 166-180 rubles (67-72 hryvnia).

Is it possible to drip Galazolin into the eyes?

Many, using Galazolin, are interested in whether it can be dripped into the eyes. So, there is only one answer - no. This tool is intended exclusively for the treatment of ENT diseases, it has nothing to do with ophthalmology

However, if you accidentally dripped Galazolin into your eyes, you should not be afraid. If the case is an isolated one, nothing terrible will happen. If a burning sensation or redness occurs, rinse your eyes with boiled water and drip okomistin. Frequent contact with such medications in the eyes often leads to a sharp decrease in vision.

Registration number:
P N014423/01 dated 09/16/2008
Trade name:
Galazolin®
International non-proprietary name: xylometazoline
Dosage form: nasal drops
Description: colorless or almost colorless transparent liquid.

Compound
1 ml of solution 0.05% and 0.1% contains:
Active substance: xylometazoline hydrochloride 0.5 mg; 1.0 mg
Excipients: sodium hydrophosphate dodecahydrate, sodium dihydrophosphate monohydrate, sodium chloride, disodium edetate, benzalkonium chloride, sorbitol, purified water.

Pharmacotherapeutic group: anticongestive agent - vasoconstrictor (α-adrenomimetic).

ATX Code: R01AA07

Pharmacological properties

Pharmacodynamics
Xylometazoline is an imidazole derivative with a sympathetic effect. It belongs to the group of local vasoconstrictors (decongestants). At low concentrations, it acts on α2-adrenergic receptors, and at high concentrations, it acts on α1-adrenergic receptors. When applied topically, xylometazoline causes constriction of the blood vessels of the mucous membrane, which leads to a decrease in edema and hyperemia of the mucous membranes of the nasopharynx, a decrease in the amount of discharge, and relief of nasal breathing.
Pharmacokinetics
With topical nasal application, it is practically not absorbed, plasma concentrations are so small that they cannot be determined by modern analytical methods. The action occurs in 5-10 minutes, and lasts for 5-6 hours.

Indications for use

Acute rhinitis of viral or bacterial origin;
- allergic rhinitis;
- acute or chronic sinusitis;
- pollinosis;
- otitis media - in order to reduce swelling of the mucous membrane of the nasopharynx.

Contraindications

Hypersensitivity to the components of the drug;
- atrophic rhinitis;
- angle-closure glaucoma;
- arterial hypertension;
- severe atherosclerosis;
- tachycardia;
- hyperthyroidism;
- pregnancy;
- surgical interventions on the meninges (in history);
- children's age up to 6 years (for 0.1 solution) and up to 2 years (for 0.05% solution);
- simultaneous use of monoamine oxidase inhibitors (MAO) and a period of up to 14 days after the end of their use.

Carefully

lactation period;
- diabetes;
- angina III-IV functional class;
- prostatic hyperplasia;
- pheochromocytoma.

Dosage and administration

Children aged 2 to 6 years: the average dose is 1-2 drops in each new move 1-2 times a day.

Adults and children over 6 years old: the average dose is 2-3 drops in each new stroke 2-3 times a day.
Do not use the drug more than 3 times a day.
The duration of the drug is no more than 3-5 days.

Side effect

With frequent and prolonged use - irritation and / or dryness of the mucous membrane of the nasopharynx, burning and paresthesia of the mucous membrane of the nasal cavity, sneezing, hypersecretion of the nasal mucosa.
Rarely - swelling of the nasal mucosa, palpitations, tachycardia, arrhythmias, increased blood pressure, headache, vomiting, insomnia, visual impairment; depression (with prolonged use in high doses).

Overdose

There have been no cases of drug overdose in adults. If too large a dose or incorrectly used, ingestion of drops and absorption of the active substance from the gastrointestinal tract may occur. Such situations were mainly observed in children. In this case, the main side effect was a pronounced sedative effect.
In case of accidental ingestion of the drug (more often in children), tachycardia, arrhythmia, increased blood pressure, drowsiness, confusion, respiratory depression or irregular breathing are noted.
Treatment is symptomatic.

Interaction with other drugs

Incompatible with MAO inhibitors and tricyclic antidepressants.

special instructions

Before use, clean the nasal passages.
Do not use the drug in patients with chronic or vasomotor rhinitis, as they tend to use the drug for more than 2 weeks.
Prolonged use of the drug (more than 2 weeks) may lead to secondary vasodilation and subsequently to iatrogenic rhinitis ( rhinitis medicamentosa). The cause of this disease is the inhibition of the release of norepinephrine from nerve endings through the excitation of presynaptic α2 receptors.