Gynoflor E: analogues and instructions for the use of candles. The drug Gynoflor - composition, instructions, contraindications and reviews Gynoflor or acilact from inflammation

The body of every person is affected by some kind of disease. Some less, some more. So, if even the most banal thrush is not treated, serious consequences can develop that will negatively affect the general state of health. Against various sexual infections, more than one drug has long been created. This number of reliable ones include Gynoflor E.

How does it affect? Who can use it and when? What side effects from such therapy can be? How much does a course of drug treatment cost? - find out today.

pharmachologic effect

Gynoflor E is a local reparative medicine. Thanks to it and its antagonistic properties, the release of bacteriocins, hydrogen peroxide, and its own secrets with antibiotic effects is activated.

This effectiveness is due to the composition, which includes acidophilus bacteria and estriol hormone.

Due to the normalization of the acid level (the breakdown of glycogen to lactic acid) and the increase in the number of beneficial microorganisms, the local protective function is enhanced.

Lactobacilli of the drug, which are also found in the environment of the woman's vagina, contribute to the active resistance to foreign bacteria, restoring the normal balance of the flora.

It also allows you to use Gynoflor E suppositories for menopausal syndrome.

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Composition and form of release

The drug Gynoflor E is made in the form of intravaginal tablets with a eubiotic concentration of 50 mg.

The amount of estriol is 0.03 mg

Also in production it is impossible to do without the following auxiliary components:

The drug is sold in packs of 6, as well as 12 pieces.

Indications for use

The drug Gynoflor E is prescribed in the following cases:

Violations of the vaginal microflora for various reasons;
bacterial vaginosis;
Thrush;
Vulvovaginitis of a non-specific nature;
Urogenital infectious pathologies;
Atrophic vaginitis due to lack of estrogen;
Bacterial secretions of unknown etiology;
Comprehensive treatment of sexual ailments.

Photo gallery of testimony:

Atrophic vaginitis

Contraindications

The drug Gynoflor E should not be used if there are restrictions in the form of:

Intolerance to the components of the drug;
Hormone-dependent tumors of a malignant nature in the organs of the reproductive system;
endometriosis;
Hemorrhagic discharge;
Hyperplasia of the endometrium.

Photos of the components of the medicinal product:

Also, Gynoflor E vaginal suppositories are not prescribed for girls without sexual activity.

Side effects

When using the drug Gynoflor E, adverse reactions may occur at the injection site:

Burning sensation;
Feeling of a foreign body;
Other uncomfortable sensations;
Redness;
puffiness;
Arterial hyperemia;

drug interaction

Gynoflor E vaginal suppositories are not combined with antibiotic drugs at the same time, since the effectiveness of beneficial bacteria greatly reduced.

Alcohol compatibility

There is no prohibition on the use of alcohol during therapy with the drug Gynoflor E. This combination does not cause any negative reactions.

Dosage and overdose

There is no information about overdose with this drug. No such cases have been recorded.

Instructions for use

Gynoflor E is placed intravaginally in the supine position.

Shelf life and storage of the drug

Gynoflor E vaginal suppositories have a shelf life of up to 3 years if they are stored at a temperature not higher than + 15 ̊ С.

special instructions

Can Gynoflor E be used during menstrual bleeding? While menstruation is on, it is worth stopping or postponing the use of the medicine

If a woman notices undissolved particles of Gynoflor E vaginal suppositories on her underwear, there is no need to worry.

All substances penetrated to the place of destination, so this does not affect the effectiveness.

If the vaginal environment is very dry, then the suppository should be rinsed with water before use.

The drug Gynoflor E does not affect the management of transport in any way.

medicinal product not prohibited pregnant and lactating women.

Price

Gynoflor E vaginal tablets are priced for 12 pcs. from 800 rubles. Cheaper price for 6 candles.

Terms of dispensing from pharmacies

You can buy a drug on a prescription sheet.

Useful video:

Analogs substitutes

The most complete analogues of Gynoflor E tablets are as follows:

consists of lactobacilli rhamnosus and reuteri. Available in the form of vaginal and oral capsules, gel and soap. Manufacturer: Jadran Galenski Laboratorij (Republic of Croatia).
It is made in the form of vaginal suppositories with ascorbic acid. Manufacturer: "Artesan Pharma" (Germany).

There are also some analogues of candles that are similar in action:

is available in oral and vaginal capsules with lactobacilli rhamnosus and reuteri. Manufacturer: Jadran Galenski Laboratorij (Republic of Croatia).
produced in the form of vaginal capsules with acidophilic lactobacilli. Manufacturer: Pharma-Vinci (Denmark).
is made in the form of a gel with a lysate of lactobacilli. Manufacturer: Se.PHARM S.r.l. (Italy).

Photo analogues:

How would you rate the effect of the drug?

1 tablet of Gynoflor E for vaginal use as active ingredients contains:

lyophilizate lactobacillus acidophilus groups eubiotics (lactobacillus acidophilus) - 50 mg (but not less than 100 million viable microorganisms);
estriol - 0.03 mg.

Auxiliary substances of the active nucleus are:

lactose monohydrate - 625.6 mg;
microcrystalline cellulose (MCC) - 183.7 mg;
carboxymethyl starch - 30 mg;
magnesium stearate - 6.67 mg;
sodium dihydrogen phosphate - 4 mg.

Release form

In pharmacies, Gynoflor is supplied in the form vaginal biconvex tablets(another name for the release form is candles Gynoflor E) oval-shaped, 50 mg each, which are fixed in aluminum foil or PVC blisters of 6 pieces. Tablets of white or light beige color with splashes (intermediate shades of these colors are possible). 1 or 2 blister strips are included in the carton box.

pharmachologic effect

The constituent components of the pharmaceutical preparation Gynoflor E are part of the physiological mechanism for maintaining normal vaginal biocenosis . This is the main purpose of using the drug in conservative therapy.

Pharmacodynamics and pharmacokinetics

After the introduction of the drug into the vagina, the constituent components are released gradually, as they decay under the influence of internal environmental factors. Freeze-dried bacteria have only a local effect and are not absorbed into the systemic circulation. Their influence is noted after a few hours.

Estriol when administered intravaginally, it can be absorbed from the inner surface of the vaginal mucosa and enter the systemic circulation. The maximum plasma concentration is observed 3 hours after administration of the pharmaceutical preparation. Estriol does not accumulate (after repeated administration, the plasma concentration corresponds to the amount of unbound) and does not affect the production of endogenous estrogen hormones ( And ), since it is their final link in the metabolic chain. The constituent components of Gynoflor are excreted in the urine within 8 hours.

Indications for use

renewal physiologically normal microflora after local or systemic antibiotic treatment;
mild to moderate severity of bacterial or (a pharmaceutical preparation can be used both as a conservative treatment and preventive disease prevention);
not specific vulvovaginitis ;
(usually sexually transmitted);
atrophic vaginitis as a result of the following etiological factors - estrogen deficiency during menopause or accompanying hormone replacement therapy ;
bacterial secretions of unknown origin ( Fluor vaginalis);
in complex drug treatment, against an infectious nature to maintain the normal microflora of a woman's body.

Contraindications

hypersensitivity, hereditary or acquired intolerance to the constituent components of a pharmaceutical product;
, dependent on estrogen (in particular, when the process is localized in the mammary glands, uterus, ovaries or vagina);
diagnosed or suspected ;
hemorrhagic discharge from the vagina of unknown origin;
hyperplasia ;
use in girls before reaching puberty (before the onset of sexual activity).

Side effects

As a rule, vaginal tablets are well tolerated by the female body, however, in some clinical cases, the following undesirable effects of treatment may be observed:

burning sensation , foreign body, or other kind of discomfort after the administration of the drug;
- redness and swelling of the mucous membrane of the vagina or external genitalia;
arterial hyperemia And vulvar itching .

In the event of accidental oral administration of a pharmaceutical preparation, no adverse effects will be observed.

Gynoflor E, instructions for use (Method and dosage)

Instructions for candles Gynoflor E instructs to deeply insert vaginal tablets into the vagina. It is recommended to carry out the manipulation in the evening, before going to bed, since at night the absorbing capacity of the body is much higher. For ease of use, the tablets are administered in the supine position, with a slight bend in the knees - thus the inlet of the female genital organs is as open as possible, and therefore the use of the drug practically does not cause discomfort.

The course of conservative therapy differs based on the indications for treatment with the drug:

For restoration of the normal microflora of the internal environment of the vagina and proliferating effect on the epithelium, 1-2 tablets are used daily for 6-12 days. More precise recommendations should be obtained from the attending physician, as they depend on various indicators of the body and the type of pathology.
At treatment of atrophic lesions during And postmenopausal the dosage of the drug is reduced to 1 tablet daily for 6-12 days. Further, maintenance therapy is carried out with an even smaller amount of a pharmaceutical preparation - 1 tablet is used 1-2 times a week. The duration of the first therapeutic phase is set by the doctor according to the individual level of hormones during the period of conservative sanitation.

For the duration of treatment with the pharmaceutical drug Gynoflor, it is recommended abstain from sexual intercourse or regularly used so that the therapeutic effect of the drug is not reduced by the exogenous intake of pathogenic or conditionally pathogenic microflora.

Overdose

Cases of drug overdose in clinical practice have not been recorded.

Interaction

Lacto acidophilus bacteria , which are one of the main components of the drug, are extremely sensitive to a wide range Therefore, local or systemic antibiotic therapy significantly reduces the effectiveness of the use of a pharmaceutical preparation.

Terms of sale

Gynoflor E is released only according to the signed receptor form.

Storage conditions

Gynoflor pharmaceutical product should be stored in a dry place, out of the reach of children and in direct sunlight, at a temperature of 2-8 degrees Celsius (in no case should the drug be frozen, because in this way all the pharmacological properties of the constituent components will be lost).

Short-term storage of Gynoflor (no more than two weeks) in a temperature range of 15 to 25 degrees Celsius will not reduce its therapeutic efficacy.

Best before date

special instructions

The constituent components of the drug Gynoflor E can not completely dissolve under the influence of internal factors of the vagina. In this case, the remnants of the vaginal tablet can be found on the underwear or bedding, but this does not affect the effectiveness of the drug (the remnants are excipients that have completed their pharmacological task).

In cases where it is noted vaginal dryness , you should wet the tablet before its introduction with a small amount of ordinary water in order to contribute to its faster dissolution. During the period of conservative treatment, women are advised to use pads if the suppositories are additionally wetted.

The drug Gynoflor E does not affect the possibility of prolonged concentration of attention, fine motor skills, coordination of movements and the ability to drive vehicles or other potentially life-threatening mechanisms.

Gynoflor E analogs

Coincidence in the ATX code of the 4th level:

The normal microflora of the internal environment of the vagina is an extremely important parameter of the physiological functioning of the female genital organs, therefore Gynoflor's analogues constitute a large group of pharmaceutical parameters, which includes both suppositories and tablets for intravaginal use.

As a rule, with individual contraindications, the therapeutic effect of the drug is replaced by the following drugs: Lactogin or Laktovag .

Synonyms

With alcohol

Alcoholic drinks in no way affect the therapeutic effects of the pharmaceutical product, and therefore the use of alcohol is not prohibited during the course of conservative treatment.

During pregnancy and lactation

The constituent components of the drug Gynoflor do not have embryotoxic ,terato- or mutagenic action on the development of the fetus, therefore the drug is allowed to be used during periods of pregnancy and breastfeeding (lactation). However, conservative therapy in first trimester recommended only under the constant supervision of qualified medical personnel and regular diagnostic tests.

Women, due to the structure of their body, often have to use vaginal suppositories. The purpose of the use of drugs can be different: antibacterial or antiviral effect, treatment of fungal infections, restoration of microflora, hormonal, and so on. Today's article will tell you about how Gynoflor E is used. Price, reviews, analogues will be presented to your attention. Despite the information received, it must be remembered that self-medication often leads to complications. With alarming symptoms, it is better to consult a doctor. After all, you cannot reliably determine the cause of your ailment, but only planned.

The drug "Gynoflor E"

Analogues and instructions for the use of this medication will be presented below. You should first familiarize yourself with the components and find out in which cases the medication is used. The composition of the preparation "Gynoflor E" includes a complex of beneficial bacteria that normally inhabit the woman's vagina. Lactobacillus acidophilus and estriol are present here. The latter is a female hormone that is responsible for tissue elasticity. A medicine is used to treat vaginal dysbacteriosis caused by antibiotics, infections, poor hygiene and other reasons. The use of the drug "Gynoflor E" is contraindicated for endometriosis and estrogen-dependent tumors, hypersensitivity and before the first menstruation. There are no official clinical data on the use of the drug during pregnancy. Therefore, the question of the possibility of such therapy is decided by the doctor. The medicine is injected directly into the vagina, 1-2 tablets per day for 6-12 days. You can buy the drug without a prescription in every pharmacy. A small package (6 suppositories) costs no more than 1100 rubles. For 12 pieces you will have to pay about 1600 rubles. As you can see, it is more profitable to buy a large package of vaginal tablets.

Medication Substitutes

The drug "Gynoflor E" has different analogues: structural and relative. In the first case, we are talking about absolute substitutes that are similar in composition. These are drugs such as Acipol, Bifidumbacterin, Laktonorm and many others. All of them are produced in Russia, while the original product is produced by a Swiss pharmaceutical company. It is known that the drug "Gynoflor E" has not only a restoring microflora effect. It is also an antiseptic. In this regard, candles "Hexicon", "Genferon", "Kipferon" and so on can be attributed to indirect analogues of the drug. Let us consider in more detail the main substitutes (analogues). "Gynoflor E" has a lot of them.

"Bifidumbacterin" - an inexpensive substitute

The drug "Gynoflor E" has analogues cheaper. For example, Bifidumbacterin. You can buy this remedy at a price of about 90 rubles for 10 suppositories. This is 10 times lower than the cost of the original drug. Bifidumbacterin vaginal suppositories are produced in Russia by the Vitapharma company. The composition of the drug includes bacteria bifidum. A distinctive feature of this tool is that it can be used not only vaginally. Candles are administered rectally in order to restore the intestinal microflora. For women, the drug is prescribed for colpitis (including hormonal), gardnerellosis, vaginal dysbiosis. The drug is recommended for expectant mothers before childbirth in order to normalize the microflora.
Reviews about this tool are mostly good. Women say that the medication is used for 5-10 days twice a day. The course of treatment requires 1-2 packs of medicines. Due to its inexpensive cost, problems with the purchase usually do not arise. It is important that the drug (unlike its expensive predecessor) has no contraindications except for hypersensitivity).

Suppositories "Acilact"

The next analogue of the candles "Gynoflor E" is the drug "Acilact". According to consumer reviews, it is often prescribed together with Bifidumbacterin. Given that the drugs are produced by one Russian company (Vitapharma), this is quite reasonable. Medicines complement each other. You already know that Bifidumbacterin contains bifidobacteria. As part of the candles "Acilact" there are acidophilic lactobacilli, as in the original Swiss medicine "Gynoflor E". A medication is prescribed to restore the microflora of the vagina and maintain the woman's immunity. It is used 1 suppository twice a day for 5-10 days. Reviews about the drug are positive. Cost plays a significant role in this: you can buy 10 suppositories for 150 rubles. Women say that after using the drug, their discharge returned to normal, itching and a feeling of dryness disappeared. In combination with Bifidumbacterin capsules, the drugs are even more effective.

"Laktonorm" - a popular substitute

The drug "Gynoflor E" has analogues that are less expensive, but not cheap either. These include the drug "Laktonorm". Suppositories are produced for 14 pieces per pack. The manufacturer is the firm "Lekko" (Russia). You can buy a pack of vaginal tablets at a price of about 500 rubles. The composition includes the same acidophilic lactobacilli as in the drug "Gynoflor E". The Russian analogue is distinguished by the absence of estriol. The medicine forms rather contradictory opinions about itself. Many consumers do not buy medicines because of the high cost. Women prefer cheaper analogues. The drug "Laktonorm" is used for the treatment and prevention of vaginosis, as well as vaginitis of a different nature (including during menopause). Doctors say that this remedy is forbidden to be used for vaginal candidiasis. The drug in this case will only worsen the patient's condition. For a course of treatment, women only need to buy one package of the drug. Capsules are inserted into the vagina for a week twice a day. It is convenient that the applicator is included in the package. Its application protects you from the penetration of pathogens that are present on the hands.

"Livarol" - the Russian analogue of candles "Gynoflor E"

This tool is produced in Russia by the pharmaceutical company Nizhpharm. A medication is produced for 5 and 10 suppositories in a pack. You can buy the drug, respectively, for 600 and 800 rubles. The composition contains ketoconazole. This substance has an antifungal effect. According to the instructions, the drug "Gynoflor E" refers to antimicrobial antiseptics. Therefore, the drug "Livarol" in some way is its analogue. Women say that this medicine is effective in the treatment of vaginal discharge of an indeterminate nature, it perfectly eliminates thrush. If you read the annotation, you can find out that "Livarol" is used to restore the microflora of the vagina after taking antibiotics. With extreme caution, the drug is used during pregnancy and lactation. It is convenient that suppositories are administered only once a day. Treatment lasts from 3 to 10 days as prescribed by the doctor.

"Kipferon" - an antiviral agent

The next substitute for candles "Gynoflor E" is the drug "Kipferon". The medicine is distinguished by the fact that there are no acidophilic microorganisms in this remedy. But despite this, suppositories are used to maintain immunity and to naturally restore the microflora of the vagina. Indications are vaginitis, candidiasis, chlamydia, dysbiosis, inflammatory infectious diseases of the vagina. It is forbidden to use the drug "Kipferon" with hypersensitivity, as well as during pregnancy. You can buy the product for 800 rubles at any pharmacy without a prescription.

Opinions formed

Often, consumers, having learned the price, refuse the drug "Gynoflor E". Women's analogues are looking for cheaper ones. Indeed, treatment with this remedy is expensive. If the medication is prescribed for 12 days, 2 suppositories per day, then you will have to buy 24 vaginal tablets. These are two large packages for 1600 rubles. Agree, not every woman can afford it. Russian substitutes for Gynoflor E candles (analogues) have a more affordable price. Even the same "Laktonorm" can be purchased for only 500 rubles, but it is also considered expensive. If you are looking for a medication with acidophilic lactobacilli at an affordable price, then experienced patients recommend choosing Acylact. The drug is inexpensive and effective. Such an opinion has developed about him among consumers. If we take into account all the substitutes for the drug "Gynoflor E", then we can say that they are safe and effective. Women get the desired effect from the use of drugs. Many drugs are acceptable for use during pregnancy. This is a plus, since it is especially important for expectant mothers to maintain a normal vaginal microflora.

conclusion

If you have been prescribed the drug "Gynoflor E", but for some reason you cannot purchase it, then you can pick up analogues. To begin with, it is still worth consulting with a gynecologist and find out which remedies are right for you. Do not self-medicate, it can lead to unpleasant consequences. All the best, don't worry!

Publication date: 04/30/17

Instructions for use. Contraindications and release form.

INSTRUCTIONS
to use the remedy
Gynoflor E

Release form
Vaginal tablets.

Package
6 pcs.

Pharmacotherapeutic group
Estrogen + eubiotic

ATX code:G02CX

Pharmacological properties
Pharmacodynamics
The active substances that make up the drug GynoflorE, estriol and acidophilic lactobacilli, are involved in the physiological mechanism for maintaining a normal vaginal biocenosis.
Lactobacillus acidophilus is one of the dominant microorganisms of the vagina of a healthy woman, which has antagonistic activity against pathogenic and opportunistic microorganisms.
Estriol is a female sex hormone, a short-acting estrogen. It has a protective trophic effect on the vaginal epithelium and has no systemic effect on the woman's body. The proliferating mature vaginal epithelium accumulates glycogen, which is necessary for the functioning of lactobacilli, which, in turn, produce lactic acid, maintaining the acidic environment of the vagina (pH 3.8-4.5), which creates unfavorable conditions for the colonization and development of pathogenic microorganisms. In addition to lactic acid, acidophilic lactobacilli produce hydrogen peroxide and bacteriocins, which also inhibit the development of pathogenic and opportunistic microorganisms.
Changes in the physiological flora of the vagina occur due to various factors: local or systemic use of antibacterial drugs, incl. due to vaginal infections, systemic diseases, poor hygiene. In these cases, the number of lactobacilli can be significantly reduced. Intravaginal use of the drug Gynoflor E improves the condition of the vaginal epithelium and restores its normal flora. Lactose, which is found in vaginal tablets as a filler, can also be fermented by lactobacilli into lactic acid.
The epithelium of the vagina becomes thinner and can also be damaged in case of hormonal disorders, in connection with which the drug Gynoflor E can be used in postmenopausal women to relieve its local symptoms (itching, burning, dryness in the vagina, pain during intercourse), contributing to the normalization of the condition of the epithelium of the vagina and urethra, reducing the frequency of dystrophic inflammatory conditions.
It has been shown in vitro that acidophilic lactobacilli within a few hours lead to the necessary decrease in pH. Estriol, with a duration of treatment of 6-12 days, provides a proliferative trophic effect on the vaginal epithelium.

Pharmacokinetics
When the drug is injected into the vagina, lyophilized bacteria and estriol are released.
Absorption of estriol from Gynoflor E was studied in postmenopausal women. After repeated use of the drug, the concentration of estriol in plasma corresponds to the concentration of endogenous unbound estriol. After the 12th day of using vaginal tablets during treatment with Gynoflor E (1 time per day), the maximum concentration of unbound estriol in the blood plasma does not differ from the initial one, which indicates the absence of systemic absorption.
The use of the drug does not affect the concentration in the blood plasma of the sex hormones present in the body of a woman - estrone and estradiol, since estriol is the end product of their metabolism.

Indications
Restoration of the normal microflora of the vagina after local and / or systemic use of antibiotics or antimicrobials (including vaginal infections: bacterial vaginosis, nonspecific vulvovaginitis; urogenital infections and sexually transmitted diseases).
Estrogen-dependent atrophic vaginitis in postmenopause, including in combination with hormone replacement therapy (HRT).

Contraindications
hypersensitivity to the drug or its components;
malignant estrogen-dependent neoplasms, incl. mammary glands, uterus, ovaries or vagina (diagnosed, in history, and if they are suspected);
endometriosis (suspected or diagnosed);
bleeding from the vagina of unknown etiology;
use in girls before sexual activity;
untreated endometrial hyperplasia.

Use during pregnancy and lactation
Use in the first trimester of pregnancy is undesirable. It is possible to use the drug Gynoflor E in the II-III trimesters of pregnancy and during breastfeeding. Undesirable effects of lactobacilli and estriol on pregnancy and the condition of the fetus / newborn were not found. However, long-term clinical studies on the effect of estriol on the fetus have not been conducted.

special instructions
The drug Gynoflor E contains components that may not dissolve completely, the remains of a vaginal tablet can sometimes be found on underwear. This does not affect the effectiveness of the drug.
In rare cases, with vaginal dryness, the vaginal tablet may not dissolve. To prevent such cases, the tablet can be moistened with a small amount of ordinary water before administration - this will contribute to its faster dissolution. Patients are advised to use pads.

Compound
Composition for 1 vaginal tablet:
Active substances: Lactobacillus acidophilus (lyophilisate) 50.00 mg (not less than 100 million viable bacteria), estriol 0.03 mg;
Excipients: lactose monohydrate 625.6 mg, microcrystalline cellulose 183.7 mg, magnesium stearate 6.67 mg, sodium carboxymethyl starch 30 mg, sodium dihydrogen phosphate 4 mg.

Description
Tablets are oval, biconvex from white to light beige with patches.

Dosage and administration
Vaginal tablets should be inserted deep into the vagina in the evening before going to bed, preferably in the supine position, with the legs slightly bent at the knees.
To restore the normal microflora of the vagina after local and / or systemic use of antibiotics or other antimicrobial drugs (including vaginal infections: bacterial vaginosis, nonspecific vulvovaginitis, urogenital infections and sexually transmitted diseases): 1-2 vaginal tablets daily for 6-12 days.
In the treatment of estrogen-dependent atrophic vaginitis in postmenopausal women: 1 vaginal tablet daily for 6-12 days, then the maintenance dose is 1 vaginal tablet 1-2 times a week.

Side effects
There may be a burning sensation (heat) in the vagina, rarely redness and itching of the vulva and vagina.

drug interaction
Lactobacillus acidophilus is sensitive to numerous antibacterial drugs (topical or systemic use). Concomitant treatment with such drugs may lead to a decrease in the effectiveness of the drug GynoflorE. Therefore, its simultaneous use with antibacterial drugs is not recommended. The use of the drug Gynoflor E together with spermicidal agents is not recommended.

Overdose
An overdose of the drug was not observed.

Storage conditions
Store at a temperature of 2 to 8 °C. Do not freeze!
Keep out of the reach of children.

Best before date
3 years. Do not use after the expiration date.

Gynoflor vaginal tablets have antimicrobial activity, restore the normal microflora of the vagina, relieve thrush. The active ingredients are components - estriol and lyophilisate of acidophilic lactobacilli. The last ingredient belongs to the group of eubiotics. Auxiliary components - lactose monohydrate, magnesium stearate, microcrystalline cellulose, etc. Gynoflor analogues are represented by drugs: Vagisan, Laktovag, Ecofemin, Hexicon, Betadine.

Mechanism of action and indications for use

The components of the drug are enclosed in biconvex tablets, each containing 50 mg of active ingredients. The substances contained in the suppositories are part of the physiological mechanism that helps maintain a full-fledged vaginal microflora. The main purpose of using the drug is the destruction of fungal microorganisms, the restoration of the vaginal biocenosis.

Lactobacilli are a key fraction of microorganisms that live in the vagina of every healthy woman. They are characterized by medicinal activity against pathogenic microorganisms. Bacteria also help to restore the balance of the physiological environment, which eliminates the likely violation of metabolic processes.

Estriol is a component of synthetic origin, its chemical structure is similar to the sex hormones of a woman, which are produced by the ovaries. Due to the therapeutic effect of the substance, an increase in the natural barrier against infections of various origins is observed.

After the introduction of the drug, the components of the drug are released gradually, disintegrate under the influence of internal factors.

For your information, lactobacilli have only a local effect, they are not absorbed into the systemic circulation, which reduces the likelihood of systemic side effects to zero.

Indications for use of the drug are extensive. It is primarily recommended for the treatment of thrush in women. It is advisable to appoint in the following situations:

Restoration of the full microflora of the vagina after antibiotic therapy;
Therapy of bacterial candidiasis and vaginosis;
Not a specific form of vulvovaginitis;
Urogenital diseases of various etiologies;
Atrophic form of vaginitis;
Therapy of bacterial secretions of unknown pathogenesis;
As part of the complex treatment of various diseases.

Vaginal tablets begin to act 1-2 hours after administration. Quickly get rid of thrush. In accordance with the instructions for use, they can be used as a preventive measure for a fungal infection.

Contraindications and side effects

Candles Gynoflor have not only indications for use, but also contraindications. In a situation where they are present, patients are prescribed analogues of the drug "Gynoflor E".

Not suitable for use in the following situations:

Organic sensitivity to medicinal components. Congenital or acquired intolerance to the drug in general or individual substances.
If a history of diagnosed tumor neoplasms of a malignant nature, which are dependent on the concentration of estrogen. In particular, they are not prescribed if the pathology was localized in the area of the mammary glands, uterus, ovaries.
Endometriosis is the growth of uterine tissue outside of it.
Allocations of hemorrhagic type of unknown etiology.
Virginity.

According to reviews, tablets for vaginal administration quickly help get rid of the symptoms of thrush. Rarely does anyone complain about the development of side effects. However, they need to be considered:

Burning, itching after drug administration;
Sensation of a foreign body in the vagina or discomfort of another kind;
An allergic reaction is redness and swelling of the mucous membrane of the internal or external genital organs.

The probability of developing side effects is less than 0.5%. Except if the tablet got inside. An overdose of the drug is impossible, there is no data on this.

Important: lactobacilli, which are the active ingredient of the drug, are extremely susceptible to antibiotic therapy. Therefore, the simultaneous use of antibiotics and the introduction of suppositories significantly reduces the therapeutic efficacy of vaginal tablets.

Instructions for use

Vaginal tablets can be purchased at a pharmacy. The price for 12 pieces is about $18. Some similar drugs will cost a little less. In accordance with the instructions, the tablet is inserted as deep as possible into the vagina.

It is better to administer the medicine in the evening just before bedtime. Since at night the absorbent property of the drug increases. To make it comfortable, it is recommended for a woman to lie down on her back, bend her knees slightly - this allows the inlet of the female genital organs to be opened as much as possible, respectively, the administration of the drug will be carried out without pronounced discomfort.

The duration of the therapeutic course, dosage and frequency of use, are determined by the reason for the appointment:

Treatment of thrush begins 3-6 days after the end of the menstrual cycle. Usually the doctor recommends the introduction of one or two tablets per day. The duration of the course varies from 7 to 14 days. The exact scheme of therapy is signed taking into account the severity of the fungal disease and other factors.
To restore normal microflora, 1-2 vaginal tablets are used every day. The duration of treatment is 6-12 days. In some cases, the course is extended if the patient has an advanced form of the disease.
For the treatment of atrophic-type damage during menopause, one tablet is prescribed every day. The course of treatment is similar to the options described above. Then, maintenance treatment is carried out, which involves the introduction of one tablet no more than twice a week. The time of the first phase of treatment is determined on an individual basis, depending on the concentration of hormones in the woman's blood.

During the treatment of thrush, it is necessary to refrain from sexual activity or use barrier contraceptives every time you have sexual intercourse. However, doctors agree that it is better to refuse sex in order to exclude a possible decrease in the effect of ongoing drug therapy.

If a woman has severe vaginal dryness, then before inserting the candle, she is dipped in plain water, which contributes to faster dissolution. During therapy, it is necessary to use pads, as some of the components leak out. This does not affect the treatment outcome.

Analogues of vaginal tablets Gynoflor

Thrush causes a lot of discomfort, significantly reduces the quality of life, manifests itself with alarming symptoms - itching, burning, pain during intercourse, vaginal discharge. If the tablets are not suitable due to existing medical contraindications, then Gynoflor E analogues are recommended:

Vagisan - a drug for thrush, is available in the form of tablets for oral administration, capsules for vaginal administration. Cannot be used in case of personal sensitivity to the composition. Recommends the introduction of one tablet per day. The course of treatment is one week. Start treatment after the menstrual cycle. There are no data on overdose. Side effects develop extremely rarely;
Laktonorm - candles, help restore the normal microflora of the vagina, contribute to the destruction of fungi, which allows you to cure thrush. Application - 1 suppository 2 times a day. The course of therapy is a week. The drug interacts with any form of drugs, this does not affect its therapeutic efficacy;
Betadine helps to get rid of thrush, is not a structural analogue of the drug Gynoflor. The main active ingredient is povidone-iodine. Vaginal suppositories have an antiseptic and antimicrobial effect. Course of treatment: 1 suppository every 24 hours for 7 days. Contraindications: hyperthyroidism, Dühring's dermatitis, simultaneous use of radioactive iodine, organic intolerance;
Pimafucin is a high-quality antibiotic with antifungal properties, based on the substance natamycin. It is permissible to use during childbearing and breastfeeding. The composition does not contain toxic components. Already after the first application, disturbing symptoms subside;
Terzhinan has a detrimental effect on opportunistic fungi. It has antibacterial, anti-inflammatory and antifungal activity. Take one tablet daily at bedtime. With extreme caution is recommended in the first trimester.

During pregnancy and lactation, therapy should be approached with caution. All drugs are prohibited in the first trimester, many are not recommended for lactation, as the substances penetrate into breast milk.

Thrush is an extremely unpleasant disease that has a tendency to recur. Only adequate treatment and a properly selected drug help to forget about negative symptoms forever. Self-treatment is fraught with the "return" of the disease with renewed vigor.