Ophthalmic gel calgel application. Calgel: instructions for use for children, dosages and analogues, reviews. for pregnant women and during lactation

Calgel is an antimicrobial pain reliever most commonly used for teething in children. The main components of Kalgel are lidocaine hydrochloride and cetylpyride chloride.

The action of the active substances that make up the drug is based on a combination of:

Lidocaine is a local anesthetic of the amide type, its action is expressed by the inhibition of nerve conduction due to the blockade of sodium channels.
Cetylpyridinium chloride is an antiseptic that inhibits the growth of bacteria and fungal flora.

Calgel for children is available in pharmacies in the form of a dental gel with a pleasant taste. In appearance, it is a homogeneous, yellowish-brown color with a specific smell of cream-gel.

The drug is used in cases of pain during teething in children over the age of five months.

Instructions for use Calgel for children

Important - Calgel for children is applied topically. A small amount of gel (up to 7 mm) should be applied to the tip of a clean finger, placed on the inflamed gum area and rubbed lightly.

According to the testimony of the child, it is possible to re-use the medicine with an interval of at least 20 minutes. The maximum frequency of application is 6 times a day.

If necessary, the simultaneous use of the drug with other drugs, it is necessary to consult a pediatrician.

Indications for use Calgel

pain syndrome during teething in children.

Before using Calgel for children, you should consult with a pediatrician.

From what age is Calgel used? Instructions for use allow use from the age of 5 months of the child.

Contraindications Calgel

kidney failure;
liver failure;
arterial hypotension;
heart failure II–III degree, impaired intraventricular conduction, bradycardia;
hypersensitivity (including to lidocaine, cetylpyridinium chloride or any other component of the drug).

Side effects of Calgel

According to reviews, Calgel rarely causes side effects and is well tolerated by young patients. Possible side effects of the drug are allergic in nature:

hives,
anaphylactic shock,
swallowing may be impaired.

If there is an allergy to calgel, use should be stopped and a doctor should be consulted to replace the drug with an analogue.

Overdose:

In case of an overdose of Calgel, there is an increase in side effects, to which vomiting, pallor of the face and skin, respiratory failure like asthma can be added. You should immediately stop using the drug and consult a doctor.

If these side effects occur, the use of Calgel should be discontinued.

Calgel analogues - list of drugs

Calgel analogues containing lidocaine and cetylpyridinium chloride are not produced.
Analogues for the rendered therapeutic effect (means for the relief of teething syndrome):

Viburkol;
Dantinorm Baby;
Dentinox;
Children's Tylenol;
Ibufen;
Kamistad;
Mundizal gel;
Holisal.

An independent decision to replace Calgel is unacceptable! Be sure to get a doctor's advice. Instructions for use Calgel, reviews and prices for analogues do not apply and cannot be used as a guide to action or dosage. When using similar drugs, a different treatment regimen may be required.

Terms and conditions of storage

The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Shelf life - 3 years.

To relieve pain during teething in infants, various means are used. The article will focus on the effective drug Calgel, the features of its use and pharmacological action.

Calgel

Used from the age of five months for pain during teething

The drug is intended for children, has a local anesthetic effect.

It is used from the age of five months for pain during teething.

It is also added to complex therapy for stomatitis and other dental diseases to eliminate pain in adult patients.

The composition is developed on the basis of two active ingredients, due to which the gel belongs to the group of combined preparations.

It is produced in the form of a yellow-brown gel with a soft consistency. No characteristic odor or taste.

The drug contains two active substances:

lidocaine hydrochloride- has an analgesic effect due to the blocking of sodium channels, which inhibits nerve patency (in 1 gram of gel - 3.3 mg of the substance);
cetylpyridinium chloride- a popular antiseptic that inhibits the growth of fungi and other harmful microorganisms (in 1 gram of gel - 1.0 mg of the substance).

In addition to the active ingredients, the composition includes substances that help the drug to be better absorbed by the body:

xylitol;
glycerol;
sorbitol solution 70%;
ethanol;
hydroxyethyl cellulose 5000;
macrogol-40, macrogol 300;
lauromacrogol;
sodium saccharin;
caramel E 150;
levomenthol;
vegetable flavoring;
purified water.

The combined agent is used for local anesthesia of the gums during the appearance of the first teeth in babies or in the treatment of various dental problems in adults.

In addition to the anesthetic effect, Calgel has an antifungal and antibacterial effect.

Blocking the transmission of impulses along the nerve endings provides lidocaine hydrochloride, and cetylpyridinium chloride inhibits the vital activity of pathogenic microflora in the mouth, thereby preventing the reproduction of microorganisms and the increase in the lesion.

But the dosage of the active components of the drug is so small that it is only enough for a local effect, the substances almost do not enter the bloodstream. This makes the use of the anesthetic safe.

Indications for use

The painful area of \u200b\u200bthe gums is treated by gently rubbing the agent into the soft tissue of the oral cavity.

Also, the drug is used as an adjuvant therapy for the following diseases:

stomatitis;
thrush;
with pain during the eruption of wisdom teeth in adults;
during the eruption of the first teeth in babies.

Calgel not only relieves pain, but also effectively destroys pathogenic microbes, relieves inflammation, removes swelling of the gums and redness.

Instructions for use

During the day, the drug is allowed to be used 6 times

The rules for the use and dosage of the drug are determined by the doctor.

As a rule, a single dosage corresponds to 7.5 mm of gel squeezed gently from the tube onto the tip of a clean finger.

The painful area of \u200b\u200bthe gums is treated by gently rubbing the agent into the soft tissue of the oral cavity.

If there is a need for re-application, it is recommended to observe an interval of at least 20-30 minutes.

During the day, the drug is allowed to be used 6 times.

It is necessary to treat the inflamed area of \u200b\u200bthe gums or mucous membrane 20 minutes before a meal (or half an hour after a meal).

The duration of the therapeutic course is 7 days, but if necessary, it can be extended up to 10 days, after which it is worth taking a break.

In the complex treatment of stomatitis and other dental diseases, Kalgel is recommended for adult patients to reduce pain.

The method of application is similar: a small amount of gel should be pointwise rubbed into the affected areas of the mucous and soft tissues (on sores, rashes, white spots). During the day, 3-6 multiple treatments are allowed with an interval of at least half an hour.

The duration of the gel depends solely on the characteristics of the organism and the extent of the inflammatory process. On average, one treatment lasts from 30 minutes to 2 hours.

Contraindications and side effects

Contraindications for the use of the drug relate to the following diseases:

Side effects with proper use of the drug are not observed.

With individual intolerance to one of the components of the gel, symptoms characteristic of allergies may appear:

hives;
anaphylactic shock.

If these signs are identified, it is necessary to urgently seek qualified help. Further use of the funds should be abandoned.

If the drug is used to treat soft tissues for a long time, then irritation of the mucous membrane is possible, so it should not be abused.

There may be some difficulty in swallowing food. Don't worry, it goes away after the drug wears off.

If, when using Calgel, the doses indicated in the instructions were violated, the following symptoms may appear:

pallor of the skin;
vomit;
bradycardia;
depression of the respiratory center;
apnea.

The presence of these signs also provides for a visit to the doctor and discontinuation of the drug.

Application during pregnancy

The use of the gel in childhood requires strict adherence to the dosage

The use of anesthetics for dental problems during pregnancy is often prohibited. Calgel is no exception.

But since the area of action of the active components is limited to soft tissues, in the treatment of dental diseases, it is allowed to treat the gums (strictly as prescribed by the doctor).

The active substances are not absorbed into the blood, they cannot affect the development of the fetus.

But the manufacturer does not indicate in the instructions information about the safety of the drug for expectant mothers due to the fact that studies of this nature have not been conducted. When breastfeeding, you should also refrain from using Calgel.

The use of the gel in childhood requires strict adherence to the dosage. The child may experience discomfort with the freezing effect, difficulty swallowing.

Interaction with other drugs

As practice shows, it is allowed to combine different drugs with a gel

When using Kalgel together with other pharmacological drugs, you should consult your doctor.

As practice shows, it is allowed to combine different drugs with the gel, because its components act locally, practically not being absorbed into the blood.

Therefore, dangerous chemical reactions are physically impossible.

Terms and conditions of storage

The general requirements for storage conditions are:

the drug does not lose its properties at a temperature regime of 0 ° - 25 °;
after opening the tube, it is recommended to use for 2 months;
the place where the medicines are located should not be accessible to children and animals;
lack of sunlight.

The shelf life is 3 years, you should focus on the date of manufacture of the gel.

Price

The cost of the drug Calgel (10 g) is 314-325 rubles. The drug is dispensed in pharmacies without a prescription. It can also be purchased online.

If Calgel is not suitable for any reason, you can use effective substitute drugs:

Babydent Dentinox Dentol Kamistad Baby Doctor

The drug is available in the range:

To relieve pain during teething in infants, it is recommended to use a drug for children.

It acts locally, like Calgel of another series, stopping pain for a while (from 30 minutes to 2 hours).

The antiseptic included in the composition allows you to fight germs, fungi and viruses, which is important for the baby, because during the game he literally pulls everything into his mouth.

Calgel for children is designed to eliminate the pain syndrome, which is noted during teething and the development of infectious diseases of the oral cavity. The manufacturer in the instructions indicates that the drug can be used from 5 months of age.

Many pediatricians prescribe a gel from 3 months if the child's gums swell and behavior becomes anxious. Before carrying out the treatment, it is worth making sure that there is no allergic reaction to the components of the pharmacological agent.

Instructions for use for children:

apply the gel to the inflamed gum area only after thorough hand washing;
on the index finger you need to squeeze out a small amount of the drug (7-7.5 mm);
rub into the gum should be in a circular motion without excessive pressure;
the treatment should be carried out for at least 20-30 seconds so that the composition has time to be absorbed into the soft tissue;
repeated use for severe pain can be done after 20 minutes;
the number of treatments per day should not exceed 6 times.

The baby cannot say what is bothering him.

Therefore, it is better for mom to focus on the signs indicating problems with the gums:

the presence of swelling;
a brighter and more saturated color indicates an inflammatory process;
yellowish clusters signal suppuration;
white spots - the development of a fungal infection.

When teething in infants, Calgel is prescribed without combination with other drugs. The substances included in the composition cope with the removal of the inflammatory process.

However, if the pain syndrome is accompanied by a high body temperature (more than 38 °), it is recommended to seek qualified medical help.

Infants do not tolerate overheating well, as a result of hyperthermia, suffocation and convulsions may appear. Only a doctor can make an adequate decision regarding treatment.

Trade name of the drug: Calgel ®

Dosage form:

Tooth gel

Compound:

Active ingredients in 1 g: lidocaine hydrochloride 3.3 mg and cetylpyridinium chloride 1.0 mg.
Excipients: sorbitol solution 70%, non-crystallizing, xylitol, ethanol, glycerol, hydroxyethylcellulose 5000, macrogol-40 hydrogenated castor oil concentrate, lauromacrogol, macrogol 300, sodium saccharinate, levomenthol, vegetable flavor 17.42.5490, caramel E 150, purified water.

Description:
soft homogeneous yellowish-brown gel with a characteristic odor, free from grains, lumps and foreign particles.

Pharmacotherapeutic group:

Local anesthetic

ATX Code A01AD11

Pharmacological properties
Combined drug. Lidocaine hydrochloride - has a local anesthetic effect, which is due to the inhibition of nerve conduction due to the blockade of sodium channels. Cetylpyridinium chloride is an antiseptic that inhibits the growth of a number of bacteria and fungi.

Indications for use
Pain syndrome during teething in children from 5 months of age.

Contraindications
Hypersensitivity to lidocaine, cetylpyridine or any other component of the drug. Renal or hepatic insufficiency, arterial hypotension, heart failure II-III degree, impaired intraventricular conduction, bradycardia.

Dosage and administration
locally. Before using Calgel, be sure to consult a pediatrician. A small amount of gel (about 7.5 mm) is applied to the tip of a clean finger and gently rubbed into the inflamed area of the child's gums. If necessary, the gel can be reapplied at intervals of at least 20 minutes, but not more than 6 times a day.

Side effect
Allergic reactions (urticaria, itching, anaphylactic shock) are possible. Possible swallowing disorder.
If during the application of the gel there are signs of allergy, then the drug should be discontinued and consult a doctor.

Overdose
Symptoms: vomiting, pallor of the skin, bradycardia, depression of the respiratory center, apnea. In case of an overdose, it is necessary to cancel Calgel and consult a doctor.

Interaction with other drugs
If you need to use other drugs, consult your doctor.

special instructions
The recommended doses should not be exceeded, since it is necessary to take into account the possibility of swallowing the drug during feeding and during sleep.

Release form
10 g in an aluminum tube, varnished on the inside, with a screw-on plastic cap.
1 tube with instructions for use in a cardboard pack.

Best before date
3 years.
Do not use after the expiration date.

Storage conditions
At a temperature not higher than 25°C.
Keep out of the reach of children.

Terms of dispensing from pharmacies
On prescription.

Manufacturer
GlaxoSmithKlinePharmaceuticals SA, Poland

Legal address.
GlaxoSmithKline Pharmaceuticals S.A., ul. Grunwaldzka, 189, 60-322, Poznan, Poland / GlaxoSmithKline Pharmaceuticals SA, Poznan, 60-322, Poland Grunwaldska, 189.

For more information please contact:
CJSC GlaxoSmithKline Trading 121614, Moscow, st. Krylatskaya, house 17, bldg. 3, fl. 5 Business Park "Krylatsky Hills"

In addition to the active ingredients lidocaine hydrochloride And cetylpyridinium chloride - Calgel contains components such as non-crystallizing sorbitol solution (70%) , ethanol , hyatellosis , lauromacrogol 600 , sodium saccharinate , sodium citrate , xylitol , ,macrogol glyceryl hydroxystearate , macrogol 300 , caramel (E150) , citric acid monohydrate , herbal flavor 17.42.5490 , water .

Release form

Produced in aluminum tubes of 10 g. Packed in cardboard boxes.

pharmachologic effect

Means of local action with analgesic, antifungal and antibacterial effect.

Pharmacodynamics and pharmacokinetics

Calgel is a combination drug. Lidocaine hydrochloride acts as a pain reliever. It blocks sodium channels, due to which the inhibition of nerve conduction is carried out. In its turn, cetylpyridinium chloride acts as a disinfectant. It prevents the growth and reproduction of a number of bacteria and fungi.

Indications for use

According to the instructions, this remedy is used for painful at the age of 5 months.

Contraindications

You can not use this tool when:

And liver failure , and heart failure II and III stages;
arterial hypotension ;
violation of intraventricular conduction ;
special sensitivity to the components of the drug;
bradycardia .

Side effects

When using the drug, the appearance of and.

Instructions for use Calgel

The tool is for topical use. It is necessary to apply a certain amount of gel (approximately 8 mm) to the fingertip and slowly rub it into the inflamed gum. The gel can be reapplied only at intervals of at least 20 minutes, but not more than six times a day.

Overdose

An overdose of the drug can lead to vomiting , bradycardia , pallor of the skin , depression of the respiratory center .

If these symptoms appear, you should immediately stop using the gel and consult a doctor.

Interaction

If this drug needs to be combined with other drugs, you should definitely consult your doctor.

Terms of sale

Calgel in pharmacies can be obtained by prescription.

Storage conditions

Keep the drug out of the reach of children at a temperature not exceeding 25°C.

Best before date

Gel Calgel is stored for 3 years.

Calgel's analogs

Coincidence in the ATX code of the 4th level:

At the moment, this drug has 4 main analogues:

Doctor Baby

Consider Kalgel's analogues in comparison. Almost all of these products contain camomile and other natural ingredients common for this kind of drugs. They are available in the form of gels. Each tool has its own characteristics.

So it is believed that it does not have side effects, but Doctor Baby , in turn, has an exclusively natural composition. As for Mundizala , then it is distinguished by the most extensive action of all the above funds.

The price of analogues may be different, but the cheapest in most pharmacies is Dentinox . At the same time, the instructions for Calgel and Dentinox reports that the composition of these funds is almost the same. The principle of their action is also similar. Instructions for the use of Calgel does not provide for anything complicated, however, in many cases, economical consumers still prefer a cheaper drug.

During pregnancy

During pregnancy, Calgel should be used with caution. It is better to do this only if the benefit of using this remedy outweighs the potential risk to the child. As a rule, experts advise during pregnancy to refrain from using this drug.

Dosage form: dental gel. Compound:

For 1 g of gel:

Components	Quantity, mg
Active ingredients:
Lidocaine hydrochloride
Cetylpyridinium chloride
Excipients:
Sorbitol solution 70% non-crystallizing
Xylitol
Ethanol 96%
Glycerol
Gietellosa
Macrogol glyceryl hydroxystearate
Lauromacrogol 600
Macrogol-300
Sodium saccharinate
Levomenthol
Herbal flavor 17.42.5490
Caramel E150
sodium citrate
Citric acid monohydrate

Description:

Soft homogeneous yellowish-brown gel with a characteristic odor, free from grains, lumps and foreign particles.

Pharmacotherapeutic group:Local anesthetic ATX:

Other drugs for topical use in diseases of the oral cavity

Pharmacodynamics:

Mechanism of action

The drug Calgel®, dental gel is an anesthetic used for application to the oral mucosa.

At the same time, it has a local anesthetic effect when applied to the mucous membrane.

Cetylpyridinium chloride has antiseptic properties.

Pharmacokinetics:

Suction

Lidocaine is rapidly absorbed from the mucous membrane.

Cetylpyridinium chloride is poorly absorbed through the oral mucosa.

Distribution

Lidocaine binds to plasma proteins, including a 1-acid glycoprotein (AKGP). The degree of binding varies and is about 66%. The binding of lidocaine to plasma proteins depends on the concentrations of lidocaine and ACGP. Any change in the concentration of AKGP can greatly affect the concentration of lidocaine in the blood plasma.

Metabolism

Lidocaine is largely metabolized in the liver. Metabolism in the liver is fast. About 90% of the incoming lidocaine undergoes dealkylation with the formation of monoethylglycinexylidide and glycinexylidide.

breeding

Metabolites of lidocaine are excreted by the kidneys, with less than 10% excreted as unchanged lidocaine.

Indications:

Calgel®, a dental gel, is prescribed for teething.

Calgel®, a dental gel, helps to quickly relieve the pain of teething and reduces the severity of gum irritation.

Calgel®, a dental gel, also has a weak antiseptic effect.

Contraindications:

Hypersensitivity to lidocaine, other amide anesthetics, cetylpyridinium or any other component of the drug;

Rare hereditary fructose intolerance;

Children's age up to 3 months.

Pregnancy and lactation:

The drug is indicated for use in children and infants, therefore information on use during pregnancy and during breastfeeding is not applicable.

Fertility

Dosage and administration:

For application to mucous membranes.

Children

Calgel®, a dental gel, is intended for children over 3 months of age.

A small amount of gel (about 7.5 mm, 0.22 g) is applied to the tip of a clean finger and gently rubbed into the inflamed area of the child's gums. If necessary, the gel can be applied repeatedly with an interval of 20 minutes, but not more than 6 times a day.

Patients with impaired renal function

Relevant data not available.

Patients with impaired liver function

Relevant data not available.

Side effects:

When using the drug Calgel®, dental gel in accordance with these instructions for use, adverse reactions are unlikely. However, there have been isolated cases of hypersensitivity to lidocaine after local injections in adults and children over the age of 12 years.

The hypersensitivity observed in these cases was expressed in the form of localized edema, accompanied by a slight difficulty in breathing or a generalized rash.

A small amount of chamomile in the herbal flavor has been documented to cause allergic reactions. Hypersensitivity to substances contained in chamomile, as a rule, manifests itself in the form of difficulty in breathing in persons predisposed to atopy. Anaphylactic reactions have been reported with herbal tea containing chamomile (asthma with herbal tea). Individuals with hypersensitivity may experience a positive skin reaction when using preparations containing chamomile.

In the event of any adverse reactions, it is necessary to stop using Calgel® and consult a doctor for advice.

The adverse reactions presented below are listed according to the damage to organs and organ systems and the frequency of occurrence. The frequency of occurrence is determined as follows: Often(≥ 1/10), often(≥ 1/100 and< 1/10), infrequently(≥ 1/1000 and< 1/100), rarely(≥ 1/10,000 and< 1/1 000), very rarely(< 1/10 000), неизвестно (невозможно оценить на основании доступных данных).

Immune System Disorders

Not known: hypersensitivity (including dermatitis).

General disorders and disorders at the injection site

Not known: irritation at the site of application, including redness of the skin (erythema).

Overdose:

Cetylpyridinium

Ingestion of cetylpyridinium in large doses may cause gastric upset and central nervous system depression. The concentrations at which overdose symptoms were noted were 70 times higher than the concentration of cetylpyridinium chloride in this preparation.

Lidocaine

Systemic toxic effects of local anesthetics (in any form of application) may include effects on the central nervous system and heart.

In the analysis of post-registration data for this drug, symptoms of overdose were not detected.

If symptoms of an overdose occur, stop using the drug and consult a doctor. The patient should be managed according to clinical indications.

Interaction:

There are no data on the interaction of the drug Calgel®, dental gel with other drugs.

There is evidence of the interaction of lidocaine (when administered intravenously) with the following drugs when taken orally: procainamide, phenytoin as monotherapy or in combination with phenobarbital, primidone or carbamazepine, propranolol and non-potassium-sparing diuretics, including, as well as thiazide.

It is unlikely that the described drug interactions are relevant to the use of the drug Calgel®, dental gel.

Special instructions: Influence on the ability to drive transport. cf. and fur.:

The drug Calgel®, dental gel, does not affect the ability to drive vehicles, mechanisms.

Release form / dosage:

Dental gel, 3.3 mg + 1.0 mg / g.

Package:

10 g in an aluminum tube, varnished on the inside, with a screw-on plastic cap.

1 tube with instructions for use in a cardboard pack.

Storage conditions:

Store at a temperature not exceeding 25 °C.

Keep out of the reach of children.

Best before date:

Do not use after the expiry date stated on the packaging.

Conditions for dispensing from pharmacies: On prescription Registration number: P N015029/01 Date of registration: 21.06.2010 / 19.03.2018 Expiration date: Perpetual Registration certificate holder: Russia Manufacturer: Representation: GlaxoSmithKline Trading, CJSC Information update date: 24.04.2019 Illustrated Instructions