Eye drops Cyclomed 1. Eye drops Cyclomed: reviews, instructions for use. Where to buy and how much

Registration certificate: P No. 012918/01

International non-proprietary name:

Cyclopentolate

Chemical Name: 2-dimethylaminoethyl-2-(1-hydroxycyclopentyl)-2-phenylacetate hydrochloride (+)

Dosage form:

eye drops.

Compound
Each ml of the drug contains:
Active substance: Cyclopentolate hydrochloride - 10 mg,
Excipients: Benzalkonium chloride - 0.1 mg, disodium edetate; sodium chloride, water for injection.

Description: clear colorless solution.

Pharmacotherapeutic group:

M-holinoblokator

ATS code: S01FA04

pharmachologic effect
Cyclopentolate, blocking M-cholinergic receptors, prevents the action of the mediator of cholinergic synapses - acetylcholine.
As a result of blocking the cholinergic synapses located in the sphincter of the pupil and in the ciliary muscle, the pupil expands due to the predominance of the tone of the muscle that expands the pupil, and the relaxation of the muscle that narrows the pupil. At the same time, due to the relaxation of the ciliary (accommodative) muscle, accommodation paralysis (cycloplegia) occurs. Pupil dilation occurs within 15-30 minutes after a single instillation. Mydriasis persists for 6-12 hours; in particularly sensitive patients, mild mydriasis may persist much longer. Residual effects of cycloplegia persist for 12-24 hours. The drug has a weak antispasmodic effect, reduces the secretion of the salivary, gastric, bronchial, sweat glands and pancreas; increases intraocular pressure; reduces the tone of the vagus nerve, which leads to an increase in heart rate with a slight increase in blood pressure.
Penetrates through the blood-brain barrier; in medium therapeutic doses, it has a moderate stimulating effect on the central nervous system, has a stimulating effect on the respiratory center.
Pharmacokinetics
Well absorbed through the conjunctiva. A significant level in the central nervous system is reached after 0.5 - 1 hour. Plasma protein binding is moderate. VA is 2 hours.

Indications

For diagnostic purposes: for ophthalmoscopy; definition of refraction.
In preoperative preparation: for pupil dilation during cataract extraction.
In inflammatory diseases of the anterior part of the eye - episcleritis, scleritis, keratitis, iridocyclitis, uveitis - as part of complex therapy.

Contraindications

Suspicion of glaucoma; glaucoma;
Post-traumatic paresis of the musculus sphincter pupillae of the iris;
Hypersensitivity to the drug.

Carefully
Children's age - up to 3 years; elderly age; intestinal obstruction; prostatic hyperplasia.

Use during pregnancy and lactation
Since the effect of the drug in pregnant women and nursing mothers has not been studied enough, use in this category of patients is possible if the expected effect outweighs the risk of possible side effects in the fetus and child.

Dosage and administration
locally. Bury in the conjunctival sac 1 - 2 drops.
For examination of the fundus: 1 - 3 times 1 drop with an interval of 10 minutes.
In the study of refraction in children and adolescents: 2-3 times a day, 1-2 drops with an interval of 15-20 minutes.
In inflammatory diseases: 1 drop 3 times a day, in severe cases, it is permissible to use 1 drop every 3-4 hours.

Side effect
Redness of the conjunctiva and a feeling of discomfort after instillation, a temporary decrease in visual acuity.
Increased intraocular pressure in patients with primary glaucoma. Weakness, nausea, dizziness, tachycardia.
In children sensitive to cyclopentolate, general weakness, nausea, dizziness, drowsiness, dry mouth, headache, and in rare cases tachycardia may occur.

Overdose
With strict adherence to the doctor's prescriptions, no cases of overdose were observed. However, if the recommended doses of the drug are exceeded, as well as when the drug is taken orally, the following symptoms may occur: dry skin and mucous membranes, tachycardia, agitation and impaired mental reactions (incoherent speech, fatigue, impaired recognition of closely spaced objects and disorientation in space, changes in emotional state); at very high doses, respiratory paralysis and coma. Treatment: in / in the introduction of a specific antidote - physostigmine, for children at a dose of 0.5 mg. If there is no effect within 5 minutes, the dose is repeated (the maximum dose should not exceed 2.0 mg). Adult antidote administered at a dose of 2.0 mg; in the absence of effect within 20 minutes, the introduction is repeated at a dose of 1-2 mg.

Interaction with other medicinal substances
The effect of the use of Cyclomed ® can be enhanced by sympathomimetics (mezaton), weakened by M-cholinomimetics (pilocarpine). Drugs with M-cholinomimetic properties, when used simultaneously with Cyclomed ®, may increase its side effects.

special instructions
When instilling the solution into the conjunctival sac, in order to avoid the solution entering the nasopharynx, it is advisable to press the lower lacrimal opening. Cyclomed ® is less effective in individuals with dark pigmented irises. In these individuals, when using the drug, residual accommodation can reach 2-4 diopters.
In children with semi-persistent or persistent spasm of accommodation, it is better to use atropine sulfate for cycloplegia.
When using Tsikpomed ® in elderly patients, control of intraocular pressure is required.
Patients with hypersensitivity to atropine do not give cross-allergy to Cyclomed ® , which allows its use in this category of patients. Against the background of the use of the drug, you should refrain from driving and other potentially hazardous activities.

Release form
Eye drops 1%.

5 ml in a plastic dropper bottle with a screw cap. Each dropper bottle, along with instructions for use, is placed in a cardboard box.
5 ml in a dark glass bottle, closed with a rubber stopper, crimped with an aluminum cap with a safety plastic cap. One glass bottle with a sterile dropper packed in a plastic bag is placed in a cardboard box along with instructions for use.

Storage conditions
At a temperature not exceeding 25 ° C in a place protected from light. Do not freeze. Keep out of the reach of children.

Shelf life
2 years.
Do not use after the expiry date stated on the packaging.
After opening the vial, the shelf life is 1 month.

Conditions for dispensing from pharmacies:

on prescription.

Produced
PROMED EXPORT HTP. LTD. 212/D-1, Green Park, New Delhi, India, at Khera Nikhla Village, Tehsil Nalagarh, Solan District, Himchal Pradesh 174 101, India
Address for submitting claims:
Representation of Promed Export Pvt. Ltd. in the Russian Federation 1 11033, Zolotorozhsky Val, 11, building 21

Medicine is developing rapidly, new drops, ointments, tablets and drugs appear every year that simplify the diagnosis and treatment of many diseases.

Today, cyclomed eye drops are a popular tool for detecting and correctly diagnosing eye diseases.

They are designed to detect abnormalities at a very early stage, when the disease has not yet entered full force.

The drug is also used at the stage of preparing the patient for surgery, it is an obligatory part of complex therapy for eye diseases.

The drug affects the eye muscles that regulate the constriction and expansion of the pupils under certain conditions, resulting in the same dilation of the pupils.

Instructions for use

Release form and composition

Cyclomed is available in drops, which are a clear and colorless liquid. The main active ingredient in the composition of the drug is cyclopentolate hydrochloride. An additional composition is represented by such substances as benzalkonium chloride, disodium edetate, sodium chloride and distilled water.

The drug is produced in plastic bottles with a drop dispenser with a volume of 5 ml.

Indications for use

for diagnostic purposes;
to ensure rest in case of circulatory disorders in the membranes, as well as injuries and inflammations of the eye (iritis, thromboembolism, choroiditis, iridocyclitis, keratitis, spasm of the retinal artery, etc.)
in the process of preoperative preparation: during cataract extraction in order to expand the pupil.

Destination options

In most cases, ophthalmologists prescribe 1-2 drops of cyclomed in each eye. The following options apply:

before ophthalmoscopy 1-3 instillations with an interval of 10 m;
when determining refraction 1-2 drops every 15-20 m. 1-3 p. in a day.
in the treatment of inflammatory diseases, it is prescribed from 1 drop 3 r. per day up to 1 p. at 3-4 o'clock.

drug interaction

With the simultaneous use of drops and sympathomimetics, for example, Mezaton, the effect of the former may be enhanced. M-cholinomimetics, for example, Pilocarpine, can weaken the effect.

Medicines that have m-anticholinergic properties can increase the effect of the side effects of Cyclomed.

Operating principle

When using the drug for the first time, you must follow the instructions of the doctor. A single instillation has a blocking effect on a part of the muscle that regulates the process of pupillary constriction, while relaxing the other part of it.

Pupils dilate 15 minutes after taking the drug, the effect lasts 12 hours.

Cyclomed has a weak antispasmodic effect, its intake helps to reduce the secretion of bronchial, salivary, sweat, gastric and pancreatic glands.

The drug increases intraocular pressure, which leads to an increase in heart rate with a slight increase in blood pressure.

At average therapeutic doses, a moderate stimulating effect on the central nervous system is observed, and a stimulating effect on the respiratory center is recorded.

Side effects

temporary decrease in visual acuity;
feeling of discomfort;
redness of the conjunctiva;
increased intraocular pressure in primary glaucoma;
weakness, dizziness, nausea, tachycardia;

Children sensitive to cyclopentolate may experience dizziness, general weakness, vomiting, drowsiness, dry mouth, headaches, and in rare cases tachycardia.

Overdose

In case of an overdose (taking the drug orally), tachycardia, dryness of the skin and mucous membranes, impaired mental reactions (fatigue, incoherent speech, disorientation in space, impaired recognition of objects located close to each other and a change in the emotional background) are observed. Taking very large doses threatens with respiratory paralysis and coma.

Impact on the ability to drive mechanisms and vehicles

During the period of taking the drug, there is a restriction on engaging in potentially hazardous activities that require high concentration and speed of reactions.

special instructions

The drug shows a lesser effect on dark pigmented irises, the residual accommodation in this case can reach from 2 to 4 diopters.

An analogue of cyclomed atropine sulfate is recommended for use in children with persistent or semi-persistent spasm of accommodation. Before using cyclomed in elderly patients, intraocular pressure should be monitored.

In patients sensitive to atropine, there are no symptoms of cross-allergy to the drug, which makes it possible to use it in this category of patients.

Terms and conditions of storage

Cyclomed is stored at a temperature that does not exceed 25 ° C, however, it must not be frozen. The shelf life of the drug is 24 months in a closed vial, an open vial can be used for medicinal purposes no more than 1 month.

You can buy the drug in a pharmacy with a prescription.

Price

The cost of cyclomed drops depends on the price of the wholesale lot, the drug is imported to Russia. The price of drops is affected by the amount of customs duties, as well as storage and transportation costs.

In Russian pharmacy chains, the cost of 5 ml of a 1% solution ranges from 400 to 500 rubles, in Ukraine the price of the drug ranges from 110 to 150 UAH

Analogues

Analogues of the drug are presented on the pharmaceutical market - drops with a similar spectrum of action, in which other chemical compounds play the role of the active component.

Analogues of Cyclomed are:

Cycloptic;
Atropine sulfate;
Tropikamid-Farmak;

Cyclomed is an eye drop from the group of m-cholinomimetics used in ophthalmology. The active substance is Cyclopentolate.

Drops are designed to block m-cholinergic receptors: there is tension in the ciliary muscle and simultaneous relaxation of the muscle that narrows the pupil. With relaxation of the ciliary muscle of the eye, paralysis of accommodation develops - cycloplegia.

Temporary accommodation paralysis restores lost eye functions in certain eye diseases and helps to distinguish accommodation spasm from myopia during diagnosis.

The drug reaches its maximum activity in 20-30 minutes after a single instillation. The pupil remains dilated for 7-12 hours after instillation, and in some cases much longer.

It has a stimulating effect on the nervous system (appears 30-60 minutes after the application of the drops), contributing to an increase in intraocular pressure and a decrease in the tone of the vagus nerve - this leads to the development of tachycardia and a slight increase in blood pressure.

Cyclomed eye drops are used for diagnostic and therapeutic purposes. Ophthalmologists use them before examining the fundus.

Cyclomed is available in the form of eye drops, which are a clear, sterile, colorless and odorless solution in 5 ml vials.

Indications for use

What do Cyclomed eye drops help with? According to the instructions, the drug is prescribed in the following cases:

With ophthalmoscopy and refraction studies.
In preoperative preparation for pupil enlargement during cataract removal.
In the complex therapy of diseases of the anterior eye of an inflammatory nature (iridocyclitis, episcleritis, keratitis, scleritis, uveitis).

Instructions for use of eye drops Cyclomed, dosage

Drops are used exclusively for instillation behind the eyelid (topically).

Dosages of eye drops, according to the instructions for use Cyclomed:

If necessary, study the fundus - 1 drop \ 3 times in each eye with an interval of 10 minutes.
In inflammatory processes - 1 drop \ 3 times a day. In some cases, an increased dosage is allowed - 1 drop every 3-4 hours. The duration of the course is 3-5 days.
In the study of refraction in adolescents, 1-2 drops are prescribed every 15 minutes \ 3 times.

During the instillation procedure, it is necessary to press the lacrimal opening so that the drug does not enter the nasopharynx.

If it is necessary to prescribe several topical drugs for the treatment of ophthalmic diseases, it is imperative to maintain a time interval of at least 10 minutes between instillations.

During the application of drops, contact lenses should be removed.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Cyclomed eye drops:

Local reactions: burning, hyperemia, swelling of the conjunctiva and the eyeball, photophobia, increased intraocular pressure, decreased visual acuity, blepharoconjunctivitis, punctate keratitis.
In rare cases, manifestations of systemic action (usually occur in children against the background of the use of a 2% solution): weakness, nausea, dry mouth, dizziness, headache, drowsiness, tachycardia, intestinal atony, bladder atony, acute urinary retention.

Contraindications

It is contraindicated to prescribe Cyclomed drops in the following cases:

Increased intraocular pressure;
Individual intolerance to the components of the drug;
Pregnancy and the period of breastfeeding;
Age of children up to 3 years;
Post-traumatic paresis of the iris.

Apply with caution:

Intestinal obstruction or suspicion of it;
Elderly patients;
Hyperplasia of the prostate;
In childhood.

Overdose

Symptoms of an overdose are dryness of the mucous membranes and skin, tachycardia, mental reactions (fatigue, incoherent speech, disorientation, changes in emotional status).

When using very high doses - respiratory arrest and coma.

Analogues drops Cyclomed, price in pharmacies

If necessary, you can replace Cyclomed with an analogue of the active substance - these are drugs:

Cycloptik (from 277.47 rubles),
Cyclopentolate-SOLOpharm.

Actions similar:

Midriacil,
Tropicamide,
Unitropic.

When choosing analogues, it is important to understand that the instructions for use of Cyclomed, price and reviews, do not apply to eye drops of a similar effect. It is important to consult a doctor and not to make an independent replacement of the drug.

Price in pharmacies in Moscow and Russia: Cyclomed eye drops 1% 5ml - from 680 to 795 rubles, according to 528 pharmacies.

Store in a dry, sun-protected place at a temperature of at least 25°C. Shelf life - 2 years.

Conditions for dispensing from pharmacies - by prescription.

The drug Cyclomed belongs to the class of so-called. mydriatics (pharmacological agents, the action of which is aimed at dilating the pupil). The mydriatic effect of Cyclomed is used to treat ophthalmic diseases of an inflammatory nature (uveitis, keratitis, etc.) for diagnostic purposes (examination of the fundus, determination of visual acuity, etc.) and in laser eye surgery (cataract treatment, retinal coagulation) for facilitating operations.

The mechanism of action of Cyclomed is similar to the action of atropine-containing drugs, while they do not have cross-reactions. Cyclomed is often prescribed as a replacement for atropine in case of individual intolerance.

The active substance of the drug is cyclopentolate hydrochloride. This substance belongs to the type of M-cholinergic blockers, acting on the receptors of certain eye muscles. Under the action of cyclopentolate hydrochloride, the ciliary muscle receptors relax, and the pupillary sphincter receptors, on the contrary, narrow, which causes temporary paralysis of the accommodative apparatus of the eye.

The mydriatic effect occurs 15-20 minutes after the use of the drug and reaches a peak after 1-1.5 hours. The effect begins to subside 6-12 hours after instillation (instillation), depending on the patient's individual susceptibility to the components of the drug. Full recovery of accommodation is observed after a maximum of 24 hours. The severity of the effect of pupil dilation depends on the color of the iris: patients with a dark iris are less susceptible to the action of Cyclomed than those with light eyes.

In addition to the effect of mydriasis, the drug is characterized by a mild antispasmodic effect, and also reduces the secretion of a number of glands, increases the heart rate (HR), which is accompanied by a slight jump in blood pressure. The drug has the ability to penetrate the blood-brain barrier, exerting a moderate stimulating effect on the central nervous system.

Dosage and release form

Cyclomed is produced in the form of eye drops of a transparent consistency, without color and pronounced odor in 5 ml bottles. The drug is easily absorbed through the conjunctiva, and does not cause discomfort if the dosage is observed.

The dosage of Cyclomed depends on the purpose of the application. For medicinal purposes, instillation of the drug is prescribed, 1-2 drops every few hours (with advanced forms of inflammatory processes in the tissues of the eyes) or once a day (at the initial stages of inflammation). For diagnostic purposes, the drug is instilled every 10-15 minutes until the onset of accommodation paralysis (usually 2-3 instillations are enough).

Side effects and contraindications

Systemic reactions - manifestations of side effects of the use of Cyclomed include:

rash and other manifestations of allergic reactions;
nausea;
dizziness;
prostration;
drowsiness;
migraine;
less often - tachycardia.

Visual responses include:

photophobia;
irritation of the conjunctiva;
increased intraocular pressure;
visual impairment.

Post-traumatic paresis of the constrictor of the pupil.
Narrow-angle or closed-angle glaucoma of the eye (or suspicion of glaucoma).
Abnormally narrow angle of the anterior chamber of the eye (anatomical feature).
Increased intraocular pressure.
Systemic reaction to atropine.
Individual intolerance to the components.

Special instructions for therapy with Cyclomed

With extreme caution, these drops are prescribed to patients in the elderly and children under three years of age, as well as people with intestinal obstruction, prostate adenoma, Down syndrome. The presence or absence of negative consequences of Cyclomed instillation during pregnancy and during lactation has not yet been determined. Drug therapy is acceptable, and during the period of gestation, if the benefit to the mother is higher than the risk of side effects for the embryo.

The mydriatic effect may be accompanied by temporary blurred vision, therefore driving is not recommended during the period of Cyclomed use.

Patients wearing must observe an interval of 15-20 minutes between instillation of the drug and putting the lenses back, due to the need for complete absorption of the drug through the conjunctiva.

Narcotic effect of Cyclomed - truth or myth?

On the Internet, you can stumble upon a number of publications related to the narcotic effect of Cyclomed when the drug is instilled into the nose. It is difficult to overdo it with the dosage of the drug by dropping it into the eye, but with nasal application, the likelihood of intoxication is much higher. This is due to the fact that the walls of the nose contain more capillaries than the iris of the eye, respectively, the diffusion of the components of the drug into the blood is also higher.

Since the active substance of Cyclomed has an effect on the central nervous system, a narcotic effect in excess of the rate of intake of cyclopentolate hydrochloride into the body is indeed possible. To get a “high”, the drug is instilled into the nose, often in horse doses. A significant overdose of cyclopentolate hydrochloride can cause visual hallucinations, in a certain environment referred to as "cartoons". In parallel, there may be temporary disorientation in space, sharp changes in the emotional background, accompanied by incoherent speech. Narcologists compare the effect of an overdose of cyclopentotate hydrochloride with the effect of the drug cannabis. But, if we evaluate both substances according to the destructiveness of the action, Cyclomed is more dangerous than "grass". A greatly exceeded dose of the drug can cause respiratory depression. The person begins to choke, feeling as if a plastic bag was put on his head. There is a feeling of indomitable thirst, the mucous membranes of the oral cavity dry up. In some cases, there may be a disorder of the functions of the gastrointestinal tract.

In the absence of urgent measures to neutralize the action of cyclopentolate hydrochloride, there is a high risk of falling into a coma with subsequent death. Regular nasal use of Cyclomed for several months can lead to inflammation of the meninges (toxic encephalitis). With periodic nasal use in limited doses, the drug is addictive, respectively, to achieve a narcotic effect, an increase in dose is required, which sooner or later leads to an overdose.

To prevent the drug from entering the respiratory tract randomly, when Cyclomed is in the eyes, it is recommended to pinch the nose.

If symptoms of an overdose of the drug are detected, it is necessary to call an ambulance. Eyewash or enema won't do anything. To neutralize the effect of the drug, Cyclomed's antidote is used - physostigmine intravenously, with a severe overdose - every 20-30 minutes. However, even after stopping the killer dose of Cyclomed with physostigmine, fans of "cartoons" may still suffer from residual effects of poisoning the body for a long time: vomiting, nausea, blurry vision, a state of inexplicable anxiety.

It is in connection with the peculiarities of the effect of the drug on the central nervous system that Cyclomed can be bought only with a prescription from a doctor.

Video - How to properly drip into your eyes?

Listed at the end of this article. It also provides information on whether this medication has analogues, whether it can be used in the treatment of children, what properties it has, what it includes, etc.

Composition, form, description and packaging of the drug

In what form is the drug "Cyclomed" produced? Instructions for use informs that this drug goes on sale in the form of eye drops. The active ingredient in this product is cyclopentolate hydrochloride. Also, the composition of the drug includes additional ingredients in the form of disodium edetate, water, benzalkonium chloride and sodium chloride.

Eye drops "Cyclomed", whose analogues are described a little further, are a colorless and transparent solution. You can buy it in a 5 ml dropper bottle, which is contained in a cardboard box.

Pharmacological properties of a local remedy

What are the properties of the local drug "Cyclomed"? Instructions for use reports that the main effects of this remedy are anticholinergic and mydriatic.

This medication is able to block M-cholinergic receptors, resulting in pupil dilation and relaxation of the eye muscles.

Pupil enlargement is observed approximately 18-22 minutes after instillation of the drug and persists for 8-11 hours (sometimes longer). By the way, residual effects can be observed in the patient even after a day.

How does the drug "Cyclomed" work? Instructions for use states that this drug may have a slight antispasmodic effect. It reduces tone and increases (slightly) intraocular pressure, and also leads to an increase in the number of heart contractions.

Against the background of the use of this remedy, the secretory work of the salivary, gastric, pancreas and bronchial glands worsens. The drug penetrates through In normal dosages, it has a stimulating effect on the brain, activating the respiratory center.

This medication is often used as a drug, instilling eye drops in the nose.

Pharmacokinetics of a local agent

Can the local preparation "Cyclomed" (eye drops) be absorbed? Reviews of experts report that this medication is quite well absorbed through the conjunctiva. The highest concentration of the main substance of the drug in the central nervous system is observed after 40-60 minutes.

The plasma protein binding of this drug is moderate, and the half-life is 110 minutes.

Indications for use

Eye drops "Cyclomed", the price of which is quite high, can be used in the following cases:

for carrying out diagnostic measures in determining refraction and ophthalmoscopy;
in the complex treatment of diseases of the anterior eye, which are inflammatory in nature (for example, scleritis, episcleritis, iridocyclitis, keratitis and uveitis);
in ophthalmic surgery (to prepare for surgery to increase the pupil during cataract extraction).

Contraindications for use

The drug "Cyclomed" for children under three years of age is prohibited to use. Also, it is not prescribed for:

glaucoma, as well as if its presence is suspected;
hypersensitivity of the patient to cyclopentolate and other components of the drug
post-traumatic paresis of the iris.

With extreme caution, this medication is recommended for people with prostatic hyperplasia and intestinal obstruction, as well as for the elderly.

The drug "Cyclomed": instructions for use

According to the attached instructions, the eye drops in question should only be applied topically. They must be instilled per eyelid 1-2 drops per day.

For diagnostic measures to identify lesions, 3 drops per day with a break of 10 minutes are used.

In the process of examining refraction in children, 2 drops of the drug are used with an exposure of 15 minutes (up to three times a day).

In inflammatory diseases of the eye, one drop of the drug is usually prescribed three times a day.

Side effects

According to experts, this medication rarely causes side effects. The most frequently manifested reactions from the eyes are: decreased visual acuity (transient), conjunctival hyperemia, discomfort after using drops, increased intraocular pressure, especially in patients with primary glaucoma.

As for common adverse reactions, they include nausea, weakness, dizziness and tachycardia.

Signs of an overdose

Cyclomed eye drops should be used only in the dosages recommended by the doctor. This is due to the fact that a large amount of the drug can cause such undesirable symptoms as tachycardia, dry skin and mucous membranes, mental reactions (disorientation, fatigue, changes in emotional status, incoherent speech), as well as coma and respiratory arrest.

As a treatment for such conditions, intravenous injections with physostigmine are used (children - 500 mcg, and adults - 2 mg).

Interaction with other medicines

The effect of the agent under consideration can be enhanced by sympathomimetics (for example, Mezaton), and weakened by m-cholinomimetics (for example, Pilocarpine).

The combination of "Cyclomed" with drugs that have m-anticholinergic properties can increase the side effects of the first.

The action of "Cyclomed" is most effective in patients with dark iris pigment. In such people, when using the medication, the residual accommodation can reach 2.0-4.0 D.

In the process of using eye drops in the elderly, careful monitoring of intraocular pressure is necessary.

Pregnancy and breastfeeding

To date, data on the safety of the use of Cyclomed eye drops in pregnant women, as well as mothers during breastfeeding, are not enough. In this regard, the drug in question can be used only in cases where the expected benefit of therapy for the patient significantly outweighs the risk of developing pathologies in the fetus or infant.

Terms and conditions of storage

According to the instructions, Cyclomed eye drops must be stored out of the reach of children and protected from light at a temperature not exceeding +25 degrees (do not freeze). The shelf life of this drug is 2 years. However, after opening the dropper bottle, this period is reduced to one month.

Eye drops "Cyclomed": analogues and cost

The price of this drug is quite high. You can buy it in a pharmacy for 380-400 rubles. As for analogues, their cost can be either higher or lower.

To date, the most popular and effective substitutes for the drug in question are the following agents: Midriacil, Appamin Plus, Tropicamide, Atropine, Irifrin.

"Cyclomed" can be replaced with other drugs only after consultation with an ophthalmologist.