Collargol solution instructions for use. Collargol: instructions for use and analogues. Contraindications for use

Collargol is a solution of eye drops based on colloidal silver with bactericidal and antiseptic properties. In ophthalmology, it is used to treat conjunctivitis, streptococcal infections, dacryocystitis.

Composition and form of release

Collargol - a solution of eye drops 2%, 3%, 5% brown, not transparent, contains: silver and albumin in a ratio of 70:30.

As a rule, it is manufactured in the prescription and production departments of pharmacies and can be packaged in glass or plastic bottles without cardboard boxes.

Pharmacological properties

Collargol solution has an antiseptic, bactericidal and astringent effect with a decrease in mucous discharge. The bactericidal effect of silver is due to its ability to be adsorbed by the membranes of bacterial cells. At the same time, the cells of bacterial agents themselves remain viable, but lose some of their functions, including the ability to reproduce. At the same time, silver, penetrating into the cells of the bacterial microflora, blocks the enzymes of the respiratory chain, affects a number of other processes leading to its death.

Indications for use

• Purulent conjunctivitis, viral conjunctivitis.
• Streptococcal eye infections.
• Dacryocystitis.

Dosage and administration

The usual prescribed dosage of Collargol for adults is 1-2 drops of a 1-3% solution, which is instilled conjunctivally. The conjunctiva must first be cleaned of secretions. Children make the drug 1 drop, using a 1.5 - 2% solution. The multiplicity of application is 2-4 times daily.

The tool is also used to diagnose the patency of the lacrimal canal with dacryocystitis. At the same time, a collarhead test is performed, when a 2% solution is introduced into the conjunctival sac, which after a short time should enter the nasolacrimal canaliculi. In the case of good patency of the canals with pressure on the zone of the lacrimal sac, the solution is released from the eye along with the tear. If the drug is delayed in the conjunctival sac for 5 minutes or more, the function of the tubule is considered impaired.

Contraindications

Individual intolerance to silver or albumin.

Side effects

Allergic reactions may occur.

Overdose

The use of the solution according to the instructions cannot cause an overdose. When swallowing the drug or making locally more than 1 g. solution, it is possible to develop symptoms of argyrosis, accompanied by irreversible changes in the eyes and skin, which acquire a silvery or bluish tint.

Drug Interactions

Collargol is not able to be absorbed into the local bloodstream and react with systemic drugs. Its topical application is undesirable with sodium chloride, novocaine, hexamethylenetetramine, iodides, and alkaloid salts. You can not use the drug with drugs, including ethyl alcohol, electrolytes, adrenomimetics.

special instructions

Collargol solution is applied only topically. Its use inside is prohibited.

Store the Collargol solution in tightly closed vials in a dark place. Do not give to children.

The shelf life of the prepared solution is no more than a month.

The price of the drug Kollargol

The cost of the drug "Collargol eye drops" in pharmacies in Moscow starts from 145 rubles.

Kollargol's analogs

Collargol is an antiseptic agent made on the basis of silver.

It is used in many areas of medical activity, mainly in ophthalmology and otorhinolaryngology, less often in urology and surgery.

The drug Kollargol instructions for use describes how approved for use in adults and children.

The required dosage form and the concentration of silver in it is prepared directly in the pharmacy.

This is done in order to achieve the maximum therapeutic effect of the drug.

Collargol is produced in several dosage forms intended for different therapeutic purposes:

1. Powder. The initial form of the drug, from which all further forms are made.
2. Eye drops - 2%, 3% and 5%. As a rule, they have the form of a clear solution with a slight odor and are sold in a special tinted glass bottle.
3. Ointment 5% and 15%.
4. Solution for external use - 0.2%, 1% and 2%.

The composition of the drug Collargol instructions for use describes two main components:

• Metal - silver ions - 70%.
• Protein - albumin - 30%.

According to the instructions for use, in addition to the above-mentioned components, the product contains other components, but their concentration has no clinical significance.

Collargol, due to its antiseptic properties, is used in the treatment of many diseases from various fields of medicine:

1. Otolaryngology:
   • Inflammation of the nasal mucosa - rhinitis (aka runny nose), its purulent forms.
   • Growth of adenoid vegetations and their inflammation (adenoids).
2. Ophthalmology:
   • Conjunctivitis, including purulent form - blennorrhea.
   • Chronic inflammation of the lacrimal sac - hr. dacryocystitis.
3. Surgery:
   • Festering wounds, including postoperative.
   • Furuncles.
   • Erysipelas - erysipelas.
   • Inflammation of the lymphatic vessels and nodes - lymphangitis and lymphadenitis.
   • Inflammation of the mucous membrane of the rectum - proctitis.
4. Urology:
   • Inflammation of the bladder - cystitis.
   • Inflammation of the urethra - urethritis.
5. Venereology:
   • Chancroid.

Nasal drops and Collargol solution show their therapeutic effect due to pronounced antiseptic and bactericidal properties, as well as the ability to reduce mucus secretion. According to the instructions for the use of Collargol, the bactericidal property of this agent is due to the ability to adsorb ("stick") to the outer surface of the bacterial cell and disrupt its normal performance.

In this case, the bacterium remains alive, but can no longer multiply and exert a pathogenic effect. Further, penetrating through the cell wall membrane, silver ions inhibit (reduce activity) certain enzymes necessary for the normal functioning of many processes, including the respiratory chain. As a result, the bacterial cells gradually die.

In most cases, Collargol's solution exhibits a sufficient level of antiseptic activity necessary for the complex treatment of the patient. Summing up the reviews of patients and doctors prescribing the drug, we can say that it shows maximum effectiveness in the treatment of conjunctivitis, rhinitis and lymphangitis. Also, judging by the results of treatment, Collargol solution and nose drops are most effective when used in the early stages of diseases.

There are no special contraindications to taking Kollargol in the instructions for use, however, it is forbidden to prescribe it in the presence of a hypersensitivity reaction to albumin or silver. Also, despite the possibility of using the drug for children of any age (including newborns), it is necessary to consult a pediatrician before using it.

There is no information regarding the effect of the drug on the body of nursing mothers and pregnant women, and therefore only the attending physician should prescribe them. In the instructions for the use of Collargol, there are no references to adverse reactions.

However, in rare cases, the following adverse events are possible:

• Argyrosis. The reaction of darkening of the skin, provoked by the accumulation of silver ions in them.
• Allergic reaction. As well as other medicines, some people may experience individual intolerance to the solution and drops of Collargol.

Collargol solution: method of application and dosage

Drops. 2% and 3% Collargol solution for ophthalmic diseases is instilled 2-3 times a day, 2-3 drops per sore eye, directly under the conjunctiva. The therapeutic course averages from 3 to 5 days. For the treatment of otolaryngological pathologies, a 2-5% solution of drops is used, which are instilled into the nose 3-6 drops 2-4 times a day for 4-6 days. To achieve the maximum effect, you should not only strictly follow the instructions for the use of Collargol, but also pre-cleanse the nasal passages from mucus.

Solution. For washing infected wounds, a 0.2-1% solution of Collargol is used. Treatment of wounds should be carried out 3-4 times a day until the wound is completely cleaned. In urology, 1% and 2% solutions are used. Washing is carried out 2-3 times a day throughout the treatment. In the treatment of intestinal diseases, microclysters with Collargol can be prescribed, but in this case it acts only as a component of a multicomponent drug.

Ointment. In surgery and venereology, Collargol is used as a 5% or 15% ointment. It is used directly above the site of the lesion - rubbed into the skin. According to the instructions for the use of Collargol, the recommended frequency of use is 2-3 times a day, however, the dosage of the agent depends on the age of the patient:

• In adults - 3 g / day.
• For children - 1 g / day.

Important

Before using the remedy, be sure to consult a doctor about the appropriateness of such treatment and dosage, and also carefully read the accompanying instructions for using Collargol solution.

Collargol (nosal drops): mechanism of action, analogues and prices

Collargol is absorbed into the blood in a small amount, therefore, when this drug is used together with other medicines, there are no adverse reactions. Before instillation into the nose, it is contraindicated to mix Kollargol with other drugs for local action on the mucous membrane of the nose and throat.

This drug can only be bought at a pharmacy, where a pharmacist can prepare a Collargol solution for instillation into the nasal cavity. This is due to the fact that the original release form of Collargol is a powder that dissolves in water to a certain concentration. The doctor must write a prescription for the drug indicating the required concentration. Kollargol (nasal drops) is prepared according to the prescription due to the short shelf life.

The average cost of Collargol in Russian pharmacies ranges from 180 to 200 rubles.

Kollargol's analogues can be divided into two groups:

• Structural.
• Pharmacological.

Structural analogs

The only structural analogue of Collargol's solution is Protargol. They are similar in composition, but the percentage ratio between silver ions and albumin is different. Collargol contains more than 10 times more silver, which is why it has a more pronounced antiseptic effect.

Pharmacological analogues

In the treatment of various pathologies, Collargol solution or nose drops can be replaced with other antiseptics:

• Betadine.
• Brilliant green.
• Iodoform.
• Salicylic ointment.
• Chlorhexidine digluconate.
• Zinc ointment.

It is highly not recommended to replace Collargol prescribed by the doctor on your own with another remedy. Most patients note a high level of effectiveness of the drug, subject to the dosage and other prescriptions of the attending physician.

Only a small proportion of patients (less than 5%) report an insufficient therapeutic effect from the use of the solution. An even smaller proportion of people (2-4%) complain about the occurrence of adverse reactions that are not contained in the instructions for the use of Collargol.

In this article, you can read the instructions for using the drug Collargol. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Collargol in their practice are presented. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Kollargol's analogues in the presence of existing structural analogues. Use for the treatment of adenoids, purulent wounds, conjunctivitis, erysipelas in adults, children, as well as during pregnancy and lactation. The composition of the drug.

Collargol- antiseptic bactericidal agent. A colloidal preparation of silver, has astringent, anti-inflammatory and more pronounced antiseptic effect than that of Protargol.

Compound

Silver + albumin + excipients.

Indications

• purulent wounds;
• adenoids;
• purulent rhinitis;
• conjunctivitis (including blennorrhea in newborns);
• erysipelas;
• lymphangitis;
• chronic urethritis;
• chronic cystitis;
• chancroid.

Release forms

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Classmates

Powder (for solution preparation).

Solution for external use 0.2%, 1%, 2% (sometimes erroneously called drops).

Eye drops 2%, 3%, 5%.

Instructions for use and method of use

0.2-1% solution is used for washing purulent wounds.

1-2% solution - for washing the bladder with chronic cystitis (inflammation of the bladder), with urethritis (inflammation of the urethra). In the form of nasal drops for purulent rhinitis and adenoids in children.

A 2-3-5% solution in the form of eye drops is used to treat purulent conjunctivitis (inflammation of the outer shell of the eye) and blennorrhea (acute purulent inflammation of the outer shell of the eyes).

With erysipelas, lymphangitis (inflammation of the lymphatic vessels), soft chancre, rubbing 15% of the ointment is prescribed - adults 3 g, children 1 g 4 times a day.

Side effect

• argyria (darkening of the skin caused by silver retention in the body);
• hypersensitivity to the components of the drug (to the elements of silver).

Contraindications

Use during pregnancy and lactation

Sufficient clinical data on the use of Collargol during pregnancy and lactation are not available.

Use in children

It is possible to use the drug in children on the recommendation of a doctor.

special instructions

It is necessary to store the drug in orange well-closed jars, protected from light.

drug interaction

Analogues of the drug Kollargol

Structural analogues for the active substance:

Analogues by pharmacological group (disinfectants):

• Azulan;
• Aquazan;
• Amident;
• Ammonia;
• Amukin;
• Argosulfan;
• Aseptolin;
• Benzamycin;
• Betadine;
• Betadine;
• Boric acid;
• Boric ointment;
• Brilliant green (brilliant green);
• Vinilin (Balm of Shostakovsky);
• Bismuth nitrate basic;
• Hexicon;
• Hexoral;
• Hydroperite;
• Hyposol N;
• Birch tar;
• Dermatol;
• Desquam;
• Ichthyol;
• Ichthyol ointment;
• Yodovidone;
• Iodoxide;
• Yodosept;
• Iodoform;
• Potassium permanganate (potassium permanganate);
• Camphor;
• Camphor alcohol;
• Cathejel C;
• Menthol alcohol solution;
• Methylene blue aqueous solution;
• Miramistin;
• Hydrogen peroxide;
• Plivasept;
• povidone iodine;
• Polyvinox;
• Protargol;
• Resorcinol;
• Romazulan;
• Salicylic ointment;
• Silver proteinate;
• Phenol;
• Ferezol;
• Formalin;
• Chlorhexidine;
• Chlorhexidine bigluconate;
• Tsindol;
• zinc oxide;
• zinc sulfate;
• Zinc ointment;
• zinc paste;
• Cyteal;
• Ethanol;
• Etony.

The pharmacy sells a large number of antiseptics. One of them is Kollargol - drops recommended for instillation into the nose for various diseases in otolaryngology, as well as dermatology and for the treatment of pathologies of the organs of vision. Before use, it is recommended to read the instructions and clarify the indications for use and contraindications.

Collargol is a drug that belongs to the group of antiseptics. It contains albumin and colloidal silver.

The drug is sold in the form of a powder, which must be dissolved in a liquid before use. Only after that a colloidal solution of Collargol is formed. It has a slight balsamic aroma and a transparent texture, without impurities and a specific shade.

In the pharmacy you can buy already prepared drops. But before buying, the pharmacist will need to explain for what purpose the medicine is needed: for the treatment of the organs of vision or for instillation into the nose for ENT diseases. This is necessary to dilute the powder in the desired consistency.

pharmachologic effect

The medicine has the ability to neutralize such pathogenic bacteria as:

1. Streptococci.
2. Staphylococci.
3. Escherichia coli.
4. The simplest microorganisms.
5. fungal spores.
6. Bacillus.
7. Pseudomonas.
8. Moraxell.

Upon contact with the mucous membrane, the active substance has the following effect:

1. Bactericidal.
2. Disinfection.
3. Antiseptic.
4. Anti-inflammatory.
5. Astringent.

When treating a surface on which an inflammatory process is present, a decrease in the production of purulent exudate is observed. The active component helps to block the synthesis of a substance that is required to increase the number and vital activity of pathogenic microorganisms.

When exposed to a significant amount of the drug, the cellular structure of microorganisms is destroyed, which provokes their death.

Indications for use

1. Protracted chronic rhinitis.
2. Purulent tonsillitis, flowing into the chronic stage.
3. Sinusitis of an infectious nature.
4. With the growth of adenoids.
5. Pharyngitis.

With the development of diseases of a viral nature, which provoke an inflammatory process in the nasal passages, accompanied by transparent secretions, Collargol is not used.

Contraindications and side effects

The solution is approved for the treatment of inflammation in the nasal passages and other diseases in otolaryngology and pediatrics, and during pregnancy.

Improper use of the drug leads to hyperemia of the skin. The patient's skin acquires a grayish tint or silver-bluish. The process occurs due to the accumulation of silver ions. The pigmentation is irreversible. Therefore, it is forbidden to use the medicine for 14 days.

Instructions for use

For each patient, a special dosage is prescribed. Before instillation of the drug into the nose, testing is required: a solution is applied to the skin of the inner surface of the forearm. After 15-30 minutes, the reaction is evaluated: with redness, peeling, rash, it is worth refusing treatment with Collargol.

The instructions for use indicate that the drug can also be prescribed to newborns from the first days of birth.

Adults are allowed to use a consistency of 2-3%. Patients need to enter 1-3 drops up to 4 times a day. But before instillation of the solution, it is necessary, both for children and adults, to rinse the nasal passages with saline.

Overdose

During the use of the medicine Collargol for the treatment of diseases in otolaryngology, no side effects were detected with an overdose.

Compatibility with other drugs

Negative interaction or increased influence of any component of the drug with the simultaneous administration of Collargol and other drugs was not detected.

Terms of sale

The drug can be purchased at a stationary pharmacy or in an online store without the recommendations of the attending physician.

Terms and conditions of storage

Collargol drops are recommended to be kept in a room where the sun's rays do not fall, and also where small children will not get the drug. You can use the medicine within 5 years after the release of the product, if the vial is not opened. In open form, the solution is stored for no more than 30 days.

Analogues

If it is not possible to use the original, the supervising doctor will recommend analogues. Such drugs have an identical spectrum of effects:

1. Ichthyol.
2. Miramistin.
3. Bismuth.
4. Hydrogen peroxide.
5. Tsiteal.
6. Tsindol.
7. Chlorhexidine.
8. Yodovidone.
9. Protargol.
10. Sialor.

It is not recommended to independently select substitutes. Incorrect dosage provokes swelling of the nasal mucosa and deterioration.