Imudon throat medicine. Analogues of imudon are cheaper. Imudon or Ismigen - which is better


Imudon is a drug that stimulates the immune system. It is quite expensive, so it is not surprising that patients want to find cheaper analogues. This article presents some of them.

The cost of Imudon is about 500 rubles.

Imudon refers to immunostimulating drugs. These are tablets that contain a complex of bacterial lysates (fragments of bacterial bodies containing antigens). The mechanism of action of Imudon is similar to vaccinations - parts of the bacteria in the preparation cannot harm a person, but can stimulate his immune system to fight the disease.

The tool contains fragments of the most common pathogens of respiratory tract infections, oral cavity and ENT organs. Imudon is prescribed both for treatment in complex therapy and for prevention during the cold season. The drug is well combined with other drugs, relatively safe for children, according to strict indications, it can be used in pregnant women.

Of the side effects, allergic reactions of varying severity are described. Cases of overdose have not been recorded, there are few contraindications - individual intolerance and dysfunction of the immune system.

The tool is produced by the French company Solvay Pharmaceuticals, it is dispensed from pharmacies without a prescription. The cost of the drug Imudon is about 500 rubles per pack, it is possible to order it at an online pharmacy with a discount and delivery.

Top best analogues and prices

List of analogues of this tool, which are no less effective than Imudon, with a price comparison:

Name Release form Price
Solution for oral administration250-350r
LozengesFrom 200r
LozengesFrom 200r
Tablets, granules for oral solutionFrom 350r
Eye drops, nasal spray, intramuscular solution250-350r
Lozenges for resorptionFrom 150r
LozengesFrom 250r
MethyluracilOintment, rectal suppositoriesFrom 100r
IRS-19Nasal sprayFrom 400r
Sublingual tabletsFrom 450r
Broncho-munalCapsulesFrom 500r

This drug is manufactured in Slovenia active ingredient - echinacea extract.

Immunal is a drug of natural origin, it stimulates the immune system by activating white hematopoietic sprouts, increasing the activity of leukocytes. The drug is safe to use, but not recommended for pregnant women.

Unlike Imudon, the substitute can be used for immunity pathologies - autoimmune pathologies and others. But Immunal often causes a hypersensitivity reaction. Which of the two drugs to prefer depends on individual characteristics.

This replacement is a Russian drug, produced in Chelyabinsk. He contains antibodies to human interferon. The mechanism of its action is somewhat more complicated than that of Imudon, respectively, in some cases, less pronounced effectiveness may be observed.

At the same time, Anaferon is considered a safer drug than Imudon. Anaferon increases the production of antibodies to viruses and bacteria, and is used for a wide range of diseases.

grammidin neo

Grammidin Neo will cost an average of 200 rubles.

It is an antimicrobial drug with antiseptic activity. Produced in Moscow. It cannot be called an analogue or alternative to Imudon, since its main action is antiseptic, and the immunostimulating effect is somewhat weaker.

Both drugs are well used in combination for colds and their complications. Both agents are not antibiotics and can only be used as adjuncts in bacterial infections.

Ribomunil is close to Imudon in terms of the mechanism of action. It contains fragments of bacteria - ribosomes. These organelles of the bacterial cell cannot have a serious harmful effect on the human body, but cause sensitization to parts of the bacteria.

It can be used with weakened immunity, since ribosomes do not contain antigens that directly enter into a pathological reaction with human proteins. The manufacturer is the French company Pierre Fabre Medication Production.

Derinat costs from 250 to 350 rubles.

This drug is distinguished by a variety of dosage forms. It can be used for eye lesions, infections of the nasopharynx, general diseases, including colds and flu.

The tool is produced in Moscow, the active ingredient is sodium deoxyribocleate. This is an organic compound that has the ability to stimulate the immune system and heal wounds of the skin and mucous membranes.

The advantage over Imudon is the possibility of using various dosage forms depending on the patient's condition. But the immunostimulating effect of Imudon is stronger.

The active ingredients are 2,4-dichlorobenzyl alcohol, amylmetacresol and levomenthol.

They have antiseptic, analgesic and anti-inflammatory effects.

Pastilles are quite pleasant in taste, so the process of their use does not cause a negative reaction in the patient. Can be used in combination with Imudon.

Lysobact contains lysozyme- a natural antiseptic that is contained in human saliva. It inhibits the vital activity of bacteria, preventing them from being swallowed.

The agent is not absorbed into the blood and is applied topically, which allows its use in pregnant women and nursing mothers.

Lysobact can also be used for pathologies of the immune system and for tumor processes in the oral cavity.

Methyluracil

Methyluracil is the generic name for the active ingredient.

It has an immunostimulating and wound-healing effect, is used in the treatment of skin lesions and hemorrhoids.

Unlike Imudon, it is applied only topically.

IRS-19

Nasal spray containing bacterial lysates. Its main difference from Imudon is the dosage form.

IRS 19 is produced in a metal bottle equipped with a convenient curved nozzle to facilitate irrigation of the nostrils.

This is the Italian analogue of Imunal. The product contains bacterial lysates applied under the tongue.

In terms of efficiency, it is approximately equal to Imunal, but, unlike it, is less safe.

Use in children under 3 years of age, pregnant and lactating women is contraindicated.

Broncho-munal

This product also contains bacterial lysates are the most common respiratory pathogens.

The composition of microorganisms is almost identical. Broncho-munal should be used with caution in children (it is better to purchase Broncho-munal for children).

Cheap analogues of Imudon for children

Can be used for children Anaferon for Children, Methyluracil, IRS-19, Broncho-munal for children, Interferon for children. All of these drugs are highly effective, while the dose of the active substance in them is designed for the child's body. It is lower than in the adult dosage form.

In children's analogues of Imudon there are flavoring and aromatic additives that will allow children to take the medicine without whims.

Generics Imudon

Generics are drugs that are completely identical in structure, but produced in cheaper conditions, due to which their cost is reduced. Imudon has no such analogues, so if there is a need to find a cheaper drug with a similar effect, you should carefully read the table - most of the drugs in it are cheaper than Imudon.

Lozenges based on bacterial lysates. They have a local immunostimulating effect, enhance the process of phagocytosis. They are prescribed for infectious and inflammatory diseases of the oral cavity, give a quick and strong pharmacological effect.

Dosage form

The drug is produced in tablets for resorption.

Description and composition

Flat-cylindrical tablets with bevelled edges. Their color is white or almost white, their surface is smooth and shiny, slight marbling is allowed. The tablets smell like mint. The drug is produced in a cardboard package of 24 and 40 pieces.

As an active substance, the drug contains a mixture of bacterial lysates, including:

  • pyogenic streptococcus group A;
  • streptococcus sanguis (green streptococcus);
  • enterococcus fecal and fecium;
  • staphylococcus aureus;
  • klebsiella;
  • corynebacteria;
  • Plaut's wand;
  • albicans;
  • lactobacilli, including acidophilus, fermentum, helveticus, Bulgarian stick.

The composition of the tablets includes the following excipients:

  • milk sugar;
  • povidone;
  • mannitol;
  • saccharin;
  • sodium bicarbonate;
  • sodium deoxycholate;
  • citric acid anhydride;
  • mint powder;
  • E 572;
  • sodium merthiolate.

Pharmacological group

The drug is a polyvalent antigenic complex - a mixture of lysates of bacteria that most often cause inflammation in the pharynx and oral cavity.

Outside, each bacterium is covered with a cell membrane. When the shell is destroyed or dissolved as a result of mechanical or chemical action, the microorganism dies. This process is called lysis. The particles of a bacterium resulting from the destruction of its shell are called lysates.

When a bacterial lysate enters the human body, the immune system perceives it as a foreign body and starts producing mononuclear phagocytes, lymphocytes, antibodies and lysozyme.

As a result, phagocytosis is activated. When Imudon tablets are resorbed, the content of secretory immunoglobulin A and increases in saliva, which leads to an increase in local immunity.

Indications for use

for adults

The drug can be used in adults for the treatment and prevention of the following diseases:

  • oral dysbacteriosis;
  • infectious diseases after tooth resection, implantation of a tooth implant;
  • violation of the integrity of the oral mucosa, provoked by wearing dentures;
  • preparation for the removal of the tonsils, as well as the period of rehabilitation after surgery;
  • inflammation of the tongue, periodontal tissues (including aphthous), superficial and deep periodontal disease;
  • infectious and inflammatory diseases of the pharynx and oral cavity, including chronic inflammation of the pharyngeal and palatine tonsils (tonsillitis);
  • erythematous and ulcerative form of gingivitis.

for children

Imudon tablets can be used in children older than 3 years for the treatment and prevention of the diseases listed above.

It is not known whether active substances pass into breast milk, so it is worth either stopping breastfeeding for the duration of treatment or choosing another drug that is compatible with breastfeeding.

So the analogue of the drug Imudon according to the therapeutic group approved for use during childbearing and breastfeeding are lozenges. This is an antiseptic agent, the therapeutic effect of which is due to its constituent lysozyme and.

Lysozyme causes the death of viruses, fungi, gram-positive and gram-negative bacteria. Vitamin B6 promotes healing of the oral mucosa and prevents ulceration. Tablets should be sucked in 2 pieces 3-4 times a day. The course of treatment is 8 days, but at the discretion of the doctor, it can be extended.

Another analogue of the drug Imudon are tablets. In addition to lysozyme, its active substances are biclotymol (it has an antiseptic, anti-inflammatory and analgesic effect) and enoxolone (stops inflammation, causes the death of viruses and bacteria). Tablets can be used in children over 6 years of age, 1 tablet every 4 hours. They need to be absorbed until they are completely dissolved. The daily dosage is 4 tablets per day. For adults, the drug is prescribed every 2 hours. Daily dosage - 8 tablets. If after 5 days of taking there is no improvement in well-being, you should consult a doctor to replace the drug. The course of therapy should not exceed 10 days, otherwise oral dysbacteriosis may develop.

In pregnant and lactating women, according to strict indications, for diseases of the throat and oral cavity, tablets can be used. This is a combined drug that contains a local anesthetic benzocaine and an antiseptic -. For children 4-12 years old, the drug is prescribed 4 tablets per day. Adults and adolescents over 12 years old are prescribed 1 tablet every 1-2 hours, but not more than 8 tablets per day.

A doctor should select an analogue of Imudon tablets, since each of them has its own contraindications and adverse reactions.

Contraindications

Imudon tablets should not be used if there is:

  • individual intolerance to the composition of the drug;
  • autoimmune pathologies;
  • age under 3 years old.

Applications and doses

for adults

In acute inflammatory processes in the pharynx and in the oral cavity, as well as exacerbation of chronic diseases in them, adults are recommended to dissolve (without chewing) the drug every 1-2 hours. Daily dosage - 8 tablets. The average duration of therapy is 10 days.

In order to prevent infectious and inflammatory diseases of the oral cavity and pharynx, tablets should be sucked without chewing every 2 hours. The daily dosage should not exceed 6 tablets. The duration of preventive courses is 20 days. It is desirable to pass them 3 or 4 times a year.

for children

For children aged 3 to 14 years, the drug is prescribed every 2 hours for the treatment and prevention of acute and chronic inflammatory diseases outside the remission phase. The maximum daily dosage is 6 tablets. The duration of therapeutic courses is 10 days, prophylactic 20 days.

It is desirable to take preventive courses during the year 3-4 times.

Children aged 14 to 18 years should be prescribed in the same dosages as for adults.

for pregnant women and during lactation

In pregnant and lactating women, Imudon tablets are not used.

Side effects

During therapy, the following adverse reactions may occur:

  • allergy, which can manifest itself as a rash on the skin, Quincke's edema, in which case it is necessary to interrupt therapy and consult a doctor to prescribe an antihistamine and adjust the further treatment regimen;
  • erythema nodosa or nodular erythema (inflammation of the vessels of the subcutaneous fat and skin, which is accompanied by the appearance of red or purple painful nodules on the arms or legs);
  • nausea, abdominal pain;
  • cough and exacerbation of bronchial asthma.
  • temperature;
  • decrease in the number of platelets;
  • rheumatic purpura (aseptic inflammation of the walls of small vessels, the appearance of microthrombi that affect the vessels of the skin and organs, the kidneys and intestines usually suffer).

Interaction with other drugs

Imudon tablets can be prescribed in combination with other medicines, since there have been no drug interactions with them.

special instructions

Children 3-6 years of age should dissolve Imudon tablets in the presence of adults.

If the patient does not consume salt or follows a low-salt diet, then he should take into account that the Imudon tablet contains 15 mg of sodium.

After resorption of the drug for an hour, it is undesirable to eat, drink or rinse your mouth, as this reduces the therapeutic effect of the drug.

If, while taking Imudon tablets in patients suffering from bronchial asthma, an exacerbation of the disease is observed, then it is worth interrupting the treatment and consulting a doctor to select another medication.

When taking the drug, inhibition is not noted, so it can be used by drivers and patients whose work requires increased attention.

Overdose

To date, no cases of overdose with Imudon tablets have been reported.

Storage conditions

Store Imudon tablets at a maximum temperature of 25 degrees, in a place where children cannot get them.

The shelf life of the drug is 24 months, after which the drug can not be used.

Despite the fact that Imudon tablets can be purchased without a doctor's prescription, self-medication with them is unacceptable, since only a specialist can correctly diagnose and prescribe an adequate treatment regimen.

Analogues

The analogues of Imudon include the following drugs:

  1. is a substitute for Imudon in the therapeutic group, the drug is produced in tablets and granules. It can be taken for the treatment and prevention of infections of the upper and lower respiratory tract in infants older than six months.
  2. is an immunostimulating agent of bacterial origin, which is available in tablets for sublingual administration. They are contraindicated in pregnant and lactating women, babies under 3 years old. They are prescribed for the treatment and prevention of infections of the upper and lower respiratory tract.
  3. is a substitute for Imudon according to the clinical and pharmacological group. It is produced in capsules, which are 3.5 mg each (allowed from 6 months old) and 7 mg each (can be taken from 12 years old). The drug is recommended for the treatment and prevention of respiratory infections, including in patients who are expecting a child and breastfeeding.
  4. Broncho-Vaxom for children is available in capsules that contain bacterial lysate as an active ingredient. The drug is designed specifically for children aged six months to 12 years.

The price of the drug

The cost of Imudon is an average of 519 rubles. Prices range from 386 to 909 rubles.

SOLVAY PHARMA SOLVEY PHARMACEUTICALS S.A.S. Pharmstandard, OOO Pharmstandard-Tomskhimfarm, OAO

Country of origin

Russia France

Product group

Immunomodulatory drugs and immunosuppressants

Immunostimulating agent

Release form

  • Lozenges - 24 pcs per pack. Lozenges - 40 pcs per pack.

Description of the dosage form

  • Tablets are white or almost white, flat-cylindrical, with a smooth shiny surface, with bevelled edges, with a mint smell, slight marbling is allowed. Tablets are white or almost white, flat-cylindrical, with a smooth shiny surface, with bevelled edges, with a mint smell, slight marbling is allowed.

pharmachologic effect

Immunostimulating drug of bacterial origin for local use in dentistry and otorhinolaryngology. It is a polyvalent antigenic complex, which includes lysates of bacteria that most often cause pathogenic processes in the oral cavity and pharynx. Imudon activates phagocytosis, increases the number of immunocompetent cells, increases the production of lysozyme, interferon, and secretory immunoglobulin A in saliva.

Pharmacokinetics

The drug mainly acts in the oral cavity, there are currently no data on systemic absorption.

Special conditions

- Children from 3 to 6 years old dissolve tablets under the obligatory adult supervision! - You should not eat and drink, as well as rinse your mouth for an hour after using Imudon, so as not to reduce the therapeutic efficacy of the drug. - When prescribing the drug to patients on a salt-free or low-salt diet, it should be borne in mind that 1 tablet of Imudon contains 15 mg of Na +. - Patients with bronchial asthma, in whom taking drugs containing bacterial lysates, causes an exacerbation of the disease (an attack of bronchial asthma), it is not recommended to use the drug. Influence on the ability to drive vehicles and control mechanisms There are no data indicating the need for any restrictions on activities related to driving a car or other mechanisms during the period of treatment.

Compound

  • 1 tab. a mixture of bacterial lysates (Imudon®) 2.7 mg, incl. Lactobacillus acidophilus Lactobacillus delbrueckii ss lactis Lactobacillus helveticus Lactobacillus fermentum Streptococcus pyogenes groupe A Streptococcus sangius groupe H Staphylococcus aureus Enterococcus faecium Enterococcus faecalis Klebsiella pneumoniae ss fuform pneumoniae Fusobacterium nucleatum scumsiacte dida albicans 0.1575 mg Excipients: in a mixture of bacterial lysates - glycine (2 mg), sodium deoxycholate (0.53 mg), thiomersal (not more than 0.0125 mg); glycine, lactose monohydrate, mannitol, sodium saccharinate, povidone, sodium bicarbonate, anhydrous citric acid, mint flavor, magnesium stearate. 1 tab. a mixture of bacterial lysates (Imudon®) 2.7 mg, incl. Lactobacillus acidophilus Lactobacillus delbrueckii ss lactis Lactobacillus helveticus Lactobacillus fermentum Streptococcus pyogenes groupe A Streptococcus sangius groupe H Staphylococcus aureus Enterococcus faecium Enterococcus faecalis Klebsiella pneumoniae ss fuform pneumoniae Fusobacterium nucleatum scumsiacte dida albicans 0.1575 mg Excipients: in a mixture of bacterial lysates - glycine (2 mg), sodium deoxycholate (0.53 mg), thiomersal (not more than 0.0125 mg); glycine, lactose monohydrate, mannitol, sodium saccharinate, povidone, sodium bicarbonate, anhydrous citric acid, mint flavor, magnesium stearate.

Imudon indications for use

  • Treatment and prevention of infectious and inflammatory diseases of the oral cavity and pharynx: - pharyngitis; - chronic tonsillitis; - preoperative preparation and postoperative period after tonsillectomy; - superficial and deep periodontitis, periodontitis, stomatitis (including aphthous), glossitis; - erythematous and ulcerative gingivitis; - oral dysbacteriosis; - infections after extraction of teeth, implantation of artificial dental roots; - ulceration caused by dentures.

And Mudon is a drug from the group of Russian-made immunostimulants. Tablets are of bacterial origin and can be used in the treatment of dental diseases and disorders of the functioning of the upper respiratory tract.

Also, the drug is used to prevent secondary infection after the implantation of an artificial tooth root has been carried out, during the preparation period, and also after tonsillectomy.

In general, the drug is well tolerated by patients of all age groups. However, due to the high cost, or in the presence of autoimmune diseases, it is necessary to replace Imudon with analogues cheaper, and their effectiveness should not be lower than the original remedy.

The drug contributes to the provision of an immunostimulating effect by the type of vaccine. The impact of Imudon is due to its ability to stimulate the process of capture and digestion of solid particles that are part of pathogenic microorganisms.

Under the influence of the drug, the quantitative content of lysozyme, interferon, immunoglobulins increases - major immune cells in the body.

Tablets consist of a polyvalent antigenic complex - a mixture of bacteria and their cleavage products into individual enzymes, which include elements of the cell walls and intracellular contents of the microorganism.

The medicine has a composition similar to the pathogens of those pathological processes that are most often observed in the mouth and pharynx, due to which the body begins to increase the production of its own protective bodies against specific types of bacteria.

Indications for use

According to the instructions for use, Imudon is used in the course of treatment and prevention:

  • Superficial and deep periodontitis, glossitis, aphthous stomatitis.
  • Dysbacteriosis of the oral cavity.
  • Catarrhal and ulcerative gingivitis.
  • Periodontitis in acute and chronic course.
  • Pharyngitis.
  • Chronic form of tonsillitis.
  • Acute and chronic infectious or aphthous stomatitis.
  • Traumatic or decubital manifestations of the mucous membranes of the oral cavity.
  • To prevent the attachment of a secondary infection before and after surgery in the oral cavity.

The drug is widely used by maxillofacial surgeons. The medicine can also be used for sore mouth caused by dentures.

Dosage for adults and children

For patients over 14 years old, the total dosage is 8 tablets per day, and Imudon must be taken at regular intervals (every 1-2 hours.)

The duration of the course during treatment acute forms or exacerbations chronic pathologies - 10 days. For prevention immunodeficiency, the dosage is reduced to 6 tablets per day, and the total duration of administration is increased to 20 days.

Children of younger age groups from (3 to 14 years) are prescribed 6 tablets per day, at least two hours should elapse between doses. The course of treatment of acute forms and exacerbations is 10 days, prevention lasts 20 days. In both cases, the number of tablets remains unchanged - 6 per day.

The total number of treatment and preventive courses is not more than four per year.

Contraindications and side effects

  • Treatment of patients under 3 years of age.
  • Therapy for individuals with autoimmune diseases.

The drug is well tolerated. According to patients' reviews, in some cases it was reported about the development of:

  • Allergic reactions: rash, urticaria, angioedema.
  • Gastrointestinal disorders: nausea, vomiting, pain impulses in the abdomen.
  • An increase in body temperature.
  • Cough and exacerbations of bronchial asthma.
  • In isolated cases, there was erythema nodosum, thrombocytopenia, hemorrhagic vasculitis.

If patients notice the occurrence of these or any other undesirable side effects, the attending physician should be informed about this as soon as possible.

List of analogues cheaper

As a prevention of ENT diseases during pregnancy, Lizobakt will be a safe and cheap replacement for the original immunostimulant.

The price of Imudon in January 2018 is from 470 rubles. for 24 pieces, from 610 rubles. for 40 tablets. If we consider a 10-day treatment course for adults, then you will need two packs of 40 tablets, which will average 1220 rubles.

Prevention will cost from 1830 rubles and will require 120 tablets. Often patients are interested in whether there are analogues of Imudon cheaper, but no less effective?

Imudon does not have exact structural analogues (generics), therefore, if necessary, the doctor can offer a list of drugs that are similar in their action from a similar pharmacological group, but with a different composition.

  • Anaferon - from 210 rubles. A homeopathic remedy that has a similar immunomodulatory and anti-inflammatory effect. Treatment begins with the manifestation of the first symptoms of the disease. After improvement occurs, it is recommended to use the tablets for 1 week - 10 days. The drug is well tolerated by patients, in rare cases, allergic reactions have been reported.
  • Derinat - from 290 rubles. An inexpensive immunostimulant that activates cellular and humoral immunity. The drug is intended for local use, preparation of a solution for rinsing the mouth, applying applications, irrigation. The drug is well tolerated by patients.
  • Ribomunil - from 260 rubles. A cheap analogue of Imudon based on bacterial ribosomes: the most common pathogens of infectious diseases that affect the upper respiratory tract and ENT organs.

At the beginning of treatment, nausea, vomiting, excessive salivation, stool disorders, and allergies may develop. This is normal and there is no need to stop the medication.

During the first 3 weeks, the medication is taken on the first 4 days of the week.
In the next 5 months - in the first 4 days of each month.

The selection of similar drugs and substitutes should be trusted by a qualified doctor. Self-medication is unacceptable, since it may not have the proper therapeutic result.

Analogues of Imudon for children

Also on the pharmaceutical market is the following list of Imudon analogues for children:

  • Bronchomunal-P - 1 capsule contains 3.5 mg of lyophilized bacterial lysate. Capsules are used 1 time per day. The course of admission is determined by the doctor, taking into account the indications prescribed in the instructions. In the event that the child cannot swallow the capsule, its contents can be dissolved in water.
  • Anaferon for children- the cost is from 210 rubles. for 20 tablets. The drug can be used in the treatment of children older than a month. The dosage regimen is also determined by the pediatrician.
  • IRS 19 is a close analogue of Imudon. Can be used in the treatment of children from 3 years. The drug shows good organic stimulation, which is manifested in the form of an increase in the common cold at the beginning of therapy.
  • Ribomunil - in the treatment of children, preference is given to the dosage form in the form of granules for internal use.

The selection of a suitable drug to replace the original is recommended to be trusted only by a pediatrician.

Imudon or Lyzobakt

Both drugs differ in their pharmacological action. If necessary, the doctor may recommend the combined use of these medicines.

Lizobakt acts locally, tablets are prescribed for the treatment of chronic and acute tonsillitis, tonsillitis, pharyngitis, gingivitis, stomatitis, erosion affecting the oral cavity.

Lizobakt is an antiseptic, which is produced in the form of lozenges. The active substance of the drug has the ability to convert insoluble bacterial membranes into a soluble mucopeptide.

Tablets are used up to 4 times a day for a week. In the future, the doctor may decide to extend the course of using the antiseptic.

Both drugs are not recommended for use in the treatment of patients who are under 3 years of age, as well as in case of individual intolerance to the active component. The cost of Lizobakt is from 280 rubles. for 30 lozenges.

Ismigen or Imudon

Ismigen, like Imudon, is presented in the form of sublingual lozenges that can be recommended to patients older than 3 years. The pharmacological action of the analogue is similar to the original due to the composition, which includes bacterial lysates:

  • Staphylococcus aureus.
  • Pyogenic Streptococcus.
  • Catarrhal micrococcus.
  • Haemophilus influenzae type c.
  • Klebsiella ozena.
  • Klebsiella pneumonia.
  • Pneumococcus.

Under the action of Ismigen, stimulation of both local and systemic immunity is observed. As a result, there is a reduction in the frequency, severity, duration of an acute respiratory infection, relief of symptoms in the form of cough, shortness of breath, fever.

The drug is often prescribed for acute, subacute and recurrent pathologies affecting the ENT organs. Imudon substitute is used from the age of 3, tablets should be taken on an empty stomach.

Isigmen is prescribed to patients with:

  • Recurrent, acute and subacute infections affecting the upper and lower respiratory tract: bronchitis, tonsillitis, pharyngitis, rhinitis, otitis, sinusitis.
  • Complications after a viral infection, including influenza.
  • For the prevention of exacerbation of chronic bronchitis.

Imudon has a wider range of indications and a more extensive composition, which makes it possible to use it in the treatment of various dental diseases, and is also prescribed to patients who have had their tonsils removed. Otherwise, the preparations are identical.

Ismigen is distinguished by a more convenient method of application: the manufacturer recommends using the medicine one tablet per day for 10 days, respectively, the course of treatment will cost less than Imudon.

The cost of Ismigen is from 505 rubles. for 10 tablets, from 1290 rubles. for 30 pcs.

Bronchomunal or Imudon

- an immunomodulatory drug with a multicomponent composition, intended for internal use. It helps to reduce the frequency and severity of the course of infectious diseases affecting the upper respiratory tract, as well as to reduce the duration of the use of drugs with antibacterial action.

It is not an exact structural analogue of Imudon, Bronchomunal contains lyophilized bacterial lysates.

The indications of the original and its substitute are similar. Bronchomunal can be used:

  • In the course of complex treatment of frequent recurrences of infectious diseases affecting the upper and lower respiratory tract.
  • The drug is prescribed during the treatment of acute and chronic bronchitis, tonsillitis, bronchial asthma, sinusitis, rhinitis.
  • The advantage of Bronchomunal is that it can be used in the treatment of acute infectious diseases that are not amenable to standard treatment regimens involving antibacterial drugs. The drug is also prescribed for the development of complications after a viral illness. Capsules are recommended to be taken on an empty stomach for 10 days-1 month.

The cost of Bronchomunal in January 2018 is from 520 rubles. for 10 capsules of 7 mg (drug for adults) and from 490 rubles. for 10 capsules of 3.5 mg (for the treatment of children).

IRS-19 or Imudon

Medicines are similar in composition, but differ in the form of release. The analogue is presented in the form of an aerosol for intranasal administration.

The drug can be used in the treatment, as well as for the prevention of the development of chronic diseases affecting the upper respiratory tract: sinusitis, pharyngitis, laryngitis, tracheitis. The aerosol is also used in preparation for a planned surgical intervention in the ENT area.

The drug IRS-19 is preferred in the case when there is no possibility of using drugs in the form of tablets, including Imudon.

The aerosol cannot be used in case of individual intolerance to active substances, in the treatment of pregnant and lactating women, children who are under 3 years old.

The cost of IRS-19 is from 490 rubles. for 20 ml. A course of prevention and treatment will cost less than a similar Imudon.

Imudon or Grammidin

Grammidin is an antiseptic for local use, which is available in the form of lozenges. Imudon and Gramidin differ in pharmacological action:

Gramidin has a pronounced bactericidal effect.

The drug is indicated for use in the treatment of patients with acute pharyngitis, tonsillitis, tonsillitis, gingivitis, stomatitis, periodontitis.

Despite the similarity of indications for admission, the drugs have different mechanisms of action and can be used together, as part of a comprehensive treatment regimen.

Unlike Imudon, Grammidin should be taken after meals. The tablet is kept in the oral cavity until it is completely dissolved, after which it is recommended to refrain from eating for several hours.

In this article, you can read the instructions for using the drug Imudon. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Imudon in their practice are presented. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Imudon in the presence of existing structural analogues. Use for the treatment of tonsillitis, stomatitis and pharyngitis in adults, children, as well as during pregnancy and lactation.

Imudon- immunostimulating drug of bacterial origin for local use in otorhinolaryngology, dentistry. It is a polyvalent antigenic complex, which includes lysates of bacteria that most often cause inflammation in the oral cavity and pharynx.

Imudon activates phagocytosis, increases the number of immunocompetent cells, increases the production of lysozyme and interferon, immunoglobulin A in saliva.

Compound

A mixture of bacterial lysates (including Lactobacillus acidophilus, Lactobacillus delbrueckii ss lactis, Lactobacillus helveticus, Lactobacillus fermentum, Streptococcus pyogenes groupe A, Streptococcus sangius groupe H, Staphylococcus aureus, Enterococcus faecium, Enterococcus faecalis, Klebsiella pneumoniae ss pneumoniae, Fusobacterium Corynebacterium pseudodiphtheriticum, Candida albicans) + excipients.

Pharmacokinetics

The drug mainly acts in the oral cavity, there are currently no data on systemic absorption.

Indications

Treatment and / or prevention of inflammatory and infectious diseases of the oral cavity and pharynx:

  • pharyngitis;
  • angina;
  • chronic tonsillitis;
  • preoperative preparation and postoperative period after tonsillectomy;
  • superficial and deep periodontitis, periodontitis, stomatitis (including aphthous), glossitis;
  • erythematous and ulcerative gingivitis;
  • oral dysbacteriosis;
  • infections after tooth extraction, implantation of artificial dental roots;
  • ulceration caused by dentures.

Release form

Lozenges.

Instructions for use and method of use

For adults and adolescents over 14 years of age with acute inflammatory diseases of the oral cavity and pharynx and exacerbation of chronic diseases, the drug is prescribed at a dose of 8 tablets per day. Tablets dissolve (without chewing) in the oral cavity with an interval of 1-2 hours. The average duration of the course of treatment is 10 days.

To prevent exacerbation of chronic inflammatory diseases of the oral cavity and pharynx, the drug is prescribed at a dose of 6 tablets per day. Tablets dissolve (without chewing) in the oral cavity with an interval of 2 hours. The duration of the course of treatment is 20 days.

For children aged 3 to 14 years, in the treatment of acute and exacerbation of chronic inflammatory diseases of the oral cavity and pharynx, the drug is prescribed at a dose of 6 tablets per day. Tablets dissolve (without chewing) in the oral cavity with an interval of 1-2 hours. The duration of the course of treatment for acute diseases is 10 days, for the prevention of exacerbation of chronic diseases - 20 days.

Side effect

  • skin rash;
  • hives;
  • angioedema;
  • nausea, vomiting;
  • stomach ache;
  • exacerbation of bronchial asthma;
  • cough;
  • erythema nodosum;
  • hemorrhagic vasculitis;
  • thrombocytopenia;
  • increase in body temperature.

Contraindications

  • autoimmune diseases;
  • children's age up to 3 years;
  • hypersensitivity to the components of the drug.

Use during pregnancy and lactation

Information on the use of Imudon during pregnancy is insufficient. Relevant data from animal experiments and epidemiological studies are not available.

special instructions

You should not eat and drink, as well as rinse your mouth for 1 hour after using Imudon, so as not to reduce the therapeutic efficacy of the drug.

When prescribing the drug to patients on a salt-free or low-salt diet, it should be borne in mind that 1 tablet of Imudon contains 15 mg of sodium.

Patients with bronchial asthma, in whom the use of drugs containing bacterial lysates, causes an exacerbation of the disease (an asthma attack), the use of the drug is not recommended.

Pediatric use

Children aged 3 to 6 years should dissolve tablets under adult supervision.

Influence on the ability to drive vehicles and control mechanisms

There is no data indicating the need for any restrictions on activities related to driving a car or other mechanisms during the treatment period.

drug interaction

No drug interactions were noted. Imudon can be used simultaneously with other drugs.

Analogues of the drug Imudon

The drug Imudon has no structural analogues for the active substance.

Analogues by pharmacological group (Immunomodulators):

  • Acridoneacetic acid;
  • Actinolysate;
  • Aktipol;
  • Alkimer;
  • Anaferon;
  • Anaferon for children;
  • Arbidol;
  • Arpetol;
  • Arpetolid;
  • Arpeflu;
  • Affinoleukin;
  • Baktisporin;
  • Bestim;
  • Broncho-munal;
  • Vilozen;
  • Wobenzym;
  • Galavit;
  • Gepon;
  • Glutoxim;
  • Groprinosin;
  • Desoxinate;
  • Derinat;
  • Zadaksin;
  • Imiquimod;
  • Immunal;
  • Immunomax;
  • Immunorm;
  • Imunorix;
  • Imunofan;
  • Influcid;
  • IRS 19;
  • Yodantipyrin;
  • Likopid;
  • Marina;
  • Milife;
  • Sodium nucleinate;
  • Neuroferon;
  • Optinat;
  • Panagen;
  • Pyrogenal;
  • Polyoxidonium;
  • Posterisan;
  • Posterized forte;
  • Profetal;
  • Respitan;
  • Ribomunil;
  • Rhinital;
  • Ruzam;
  • Splenin;
  • Sporobacterin;
  • Stemokin;
  • Stimforte;
  • Superlymph;
  • Taktivin;
  • Tamerite;
  • Timalin;
  • Thymogen;
  • Thymusamine;
  • Uro-Vaxom;
  • Ferrovir;
  • Phlogenzyme;
  • Ergoferon;
  • Estifan;
  • Echinacea;
  • Echinocor.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.