But shpa in the vein. No-shpa: instructions for use No-shpa. The active substances of analgin or but shpa, which is more effective

How to apply "No-shpu" intramuscularly? Let's figure it out in this article.

The drug "No-shpa" is a drug based on the substance drotaverine, which is produced in the form of tablets and ampoules. The drug gives an antispasmodic effect and is used in the treatment of spastic syndrome of the digestive tract, genital, hepatobiliary and urinary systems. In addition, this medication relieves spasms of cerebral vessels in case of headaches resulting from overstrain as a result of depression and neuroses, and peripheral vessels in case of Raynaud's disease or endarteritis.

The active substance is a derivative of papaverine. The non-proprietary international name of the drug "No-shpa" is "Drotaverine". According to the clinical and pharmacological classification, it is classified as a myotropic antispasmodic. In terms of its properties, the substance is very similar to papaverine, but it has a longer and more pronounced relaxing effect on muscle fibers.

The effectiveness of a pharmacological agent is due to its ability to have a depressing effect on the phosphodiesterase enzyme, which, through a series of chemical reactions, is able to catalyze the inactivation of myosin chain kinase. This kinase phosphorylates myosin and induces muscle contraction. When it is stopped, muscle relaxation is maintained. The positive properties of the drug also lie in the selective suppression of PDE only of the fourth type, which does not affect the third type enzyme and does not cause negative side effects from the vessels and the heart.

Drotaverine causes muscle relaxation in the event of spasms of both neurogenic and myogenic origin and, regardless of the type of innervation, relaxation of muscle fibers. A significant advantage of this drug is that there is no stimulating effect on the cholinergic system, as a result of which No-shpa can be used in people suffering from a disease such as glaucoma. However, some caution must be observed when taking it, especially in the presence of prostatic hypertrophy, since symptoms of urinary retention due to relaxation of the detrusor in the bladder are possible. So "No-shpa" intramuscularly is prescribed very often.

Composition and form of release

The medical product "No-shpa" for intramuscular injection is produced in glass ampoules, which contain 2 ml of injection solution. The volume of the active element in 1 ml is 20 mg of drotaverine. Injections can be made by intra-arterial, intravenous and intramuscular administration. The solution has a bright yellow-green color.

Indications for appointment

Indications for the use of the pharmacological agent "No-shpa" intramuscularly are the prevention and treatment of organ functional disorders and pain syndrome caused by:

spasms of the muscles of the digestive organs of the tract with ulcers, gastritis, dyskinesia, pancreatitis, spastic enteritis, proctitis or colitis, as well as in the event of spasms of the pylorus or cardia, irritable bowel, development of flatulence, spastic constipation, tenesmus;
violation of the functionality of the hepatobiliary system during inflammatory processes in the gallbladder or its ducts, hyperkinetic forms of biliary dyskinesia, cholelithiasis;
excessive excitability of the uterus during pregnancy;
spasms of the urinary system with the development of nephrolithiasis, pyelitis, urolithiasis, neurogenic bladder, pyelonephritis, cystitis;
spasms of the uterine pharynx during the birth process;
prolonged opening of the uterine pharynx;
postpartum contractions;
the threat of spontaneous miscarriage;
menstruation.

That's what it says in the instructions. "No-shpa" intramuscularly is also used in the event of spasms of cerebral and peripheral vessels. It is effective in postoperative colic due to gas retention, preparation for instrumental studies, postcholecystectomy syndrome.

Application for children injections "No-shpa"

Children under six years of age are prohibited from injecting the drug intramuscularly. It is important to know that the main substance of the drug is synthesized artificially. In other words, it is not a natural element. Therefore, children "No-shpu" intramuscularly are usually used only as directed by a specialist.

The drug is a good antispasmodic, but does not have an analgesic effect, such as Analgin and similar drugs. In addition, it has some contraindications for use, they should also be taken into account when treating children.

Instructions for use for injections "No-shpa" reports that this medicine is usually prescribed to small patients in the following cases:

which is accompanied by high fever and coldness of the extremities.
Spasms in bronchitis or stenoses, causing violent coughing.
Spasms causing headache.
Renal or intestinal colic.
Excessive painful gas formation.
Spasm of smooth muscles with pyelitis or cystitis.
Spasms with gastritis or colitis.

Contraindications for the use of No-shpa injections for children are:

age up to 6 years;
low blood pressure in a child;
intolerance to drotaverine;
vascular diseases;
bronchial asthma;
suspicion of intestinal obstruction;
suspected acute appendicitis;
insufficiency of the liver, kidneys.

In accordance with the instructions for use, No-shpy injections can be carried out during pregnancy.

Application during pregnancy

Among the medicines that are widely used during pregnancy, "No-shpa" plays a special role. Being a powerful antispasmodic, this medicine eliminates any pain associated with temporary dysfunction of the digestive tract in expectant mothers. In addition, during pregnancy, this medication is absolutely safe, it can be used without any concerns.

However, even taking into account these properties of the drug, care should be taken when using it during this period, since it has certain indications for use, contraindications and negative side reactions.

During pregnancy, "No-shpa" intramuscularly can be prescribed for uterine hypertonicity and the threat of preterm birth. At the first symptoms of premature birth or the threat of spontaneous miscarriage, such as pulling pain in the lower abdomen and a feeling of fullness in this area, a single application of "No-shpa" in most cases completely eliminates uterine hypertonicity and helps to maintain pregnancy.

Another indication for the use of this pharmacological drug is a spasm of the smooth muscles of the uterus and cervix during childbirth. This situation is dangerous because the child is in a clamped state - excessive muscle tension of the myometrium contributes to its expulsion from the uterus, however, the shortened neck prevents it from moving through the birth canal. In most cases, one dropper with this drug solution is enough to restore the normal birth process. The dosage of "No-shpy" intramuscularly must be strictly observed.

Contraindications

The main contraindication to the use of this drug, as well as many other drugs, is the manifestation of severe disorders of the liver, kidneys, heart, due to the insufficiency of their functions.
In addition, the drug "No-shpa" is not prescribed during breastfeeding, since drotaverine and other representatives of this pharmacological category can penetrate into mother's milk.
The use of the drug is allowed from the age of 6, but only in tablet form, since studies on the effects of injection solutions have not been conducted, in accordance with which the use of the drug parenterally is contraindicated.
Taking the medication is contraindicated in the presence of high sensitivity to the active element or other substances from its composition.
This medicinal product can only be used with certain precautions for low blood pressure due to the high likelihood of collapse, as well as during pregnancy.

What is the dosage of "No-shpy" intramuscularly?

Dosage regimen and methods of administration

A single dosage of the drug "No-shpa" in the form of solutions for intramuscular, intraarterial and intravenous administration, depending on medical indications, is 1-2 ampoules. The frequency of such injections is 1-3 times a day. How to administer "No-shpu" intramuscularly is indicated in the instructions.

During labor or after an abortion, it is allowed to administer the drug in an amount of 80 mg with a time interval of at least 2 hours. How long does "No-shpa" work? Intramuscular and intravenous injection allows you to get the desired result after 5 minutes. That is why the injections of this medication are widespread.

Side effects

Negative side reactions that can occur when using this pharmacological drug are extremely rare. Most often, its action negatively affects the nervous system, gastrointestinal tract, blood vessels and heart.

Nervous system: cephalgia, dizziness, sleep disturbance.
Circulatory system: increased or rapid heartbeat, a feeling of heat, a violation of the rhythm of the heartbeat, a decrease in blood pressure (sometimes up to the occurrence of collapse), atrioventricular blockade.
Digestive system: dyspepsia, nausea, stool disorders.

In addition to the above negative effects of this medication, there is some information about side effects such as respiratory failure, excessive sweating, and allergic reactions. Locally, redness or a burning sensation may occur. Most often, this manifests itself when the dosage of No-shpy injections is not observed.

There are also special instructions that should be strictly followed when using the No-shpa medication:

It is necessary to observe increased precautions in the treatment of patients who suffer from atherosclerosis of the coronary arteries or low blood pressure.
The drug is approved for use in the complex therapy of hypertensive crisis.
The issue of driving a vehicle when using a drug is decided on an individual basis, especially if its negative impact occurs. At the same time, it is desirable to abandon driving and activities associated with the use of complex mechanisms when using an antispasmodic in injectable forms. If dizziness occurs after the introduction of "No-shpa" intramuscularly, it is prohibited to perform these types of work.
According to clinical studies, this medicinal product does not have an embryotoxic or teratogenic effect. Nevertheless, it is necessary to be aware of the possible risk to the fetus and use the medication only for strict medical reasons with caution. The use of the drug during pregnancy in the form of injections is undesirable.
The use of an antispasmodic during labor can cause the development of postpartum atonic bleeding.
The pharmacological agent contains metabisulphite (sodium disulfite) as an auxiliary element, which must be taken into account in the presence of hypersensitivity to it.
With parenteral administration of this medication, patients suffering from hypotension should take a horizontal position of the body due to the high likelihood of collapse.

What else does the instruction to "No-shpe" (intramuscularly) tell us?

Drug interaction

Drotaverine, like other papaverine derivatives that inhibit PDE enzymes, can reduce the anti-Parkinsonian properties of levodopa, as well as increase muscle rigidity and tremor manifestations. With simultaneous therapy with other antispasmodic drugs, mutual potentiation of antispasmodic effects can be observed. This pharmacological drug in injectable form enhances the decrease in blood pressure provoked by the use of antidepressants, quinidine or procainamide. This is confirmed by the instructions for use for injections of "No-shpy" intramuscularly.

This drug reduces the spasmodic effectiveness of morphine. When using phenobarbital, there is an increase in the antispasmodic effect of the No-shpa drug. Given the high level of binding to plasma proteins (more than 80%), the possibility of competition of this medicinal product with drugs that have the same feature cannot be ruled out. Given this fact, in the case of using a combination of such drugs, it is possible to increase the toxic effect of the drugs taken.

Analogues

The medical product "No-shpa" in the form of solutions for injection has many analogues that have the same composition, but different bioequivalence and bioavailability. These medicines include:

"Nosh-bra" is a medicine from the category of myotropic antispasmodics. In terms of pharmacological properties and chemical structure, it is close to papaverine, but it has a longer and stronger effect. Reduces the level of calcium ions entering smooth muscle cells (suppresses phosphodiesterase, promotes the accumulation of intracellular cAMP). Reduces muscle tone of organs and peristalsis, dilates blood vessels. Does not affect the autonomic nervous system, does not penetrate into the central nervous system. The presence of a direct effect on smooth muscles allows the use of this drug as an antispasmodic in situations where drugs of the M-anticholinergic class are contraindicated (prostatic hyperplasia, angle-closure glaucoma).
"Spazmol" is a medicine that is an antispasmodic myotropic effect. A distinctive feature of this pharmacological drug is the presence of a long-term effect. The drug affects not only the smooth muscles of the internal organs, but also the walls of blood vessels. You can take it to prevent the development of spasms or their presence in colitis, cholelithiasis, to eliminate spasms of the digestive tract, the brain, in order to reduce the tone of the uterus, dilate blood vessels, reduce intestinal motility.
"Spakovin" is an antispasmodic of myotropic efficiency, similar in properties to papaverine, but superior to it in efficiency and duration of exposure. Reduces the tone of internal organs, their motor activity and has a vasodilating effect.

Other analogues of the drug "No-shpa" are:

"Drotaverine hydrochloride";
"Papaverine";
"Drotaverin Forte";
"Spazgan";
"Kuplaton";
"Niaspam";
"Spasmolysin";
"Disflatil";
"Kidakol";
"No-x-sha";
"Spasmomen".

Price

The cost of this drug in the form of ampoules No. 5 is from 70 to 190 rubles per package, in the form of ampoules No. 25 - up to 320 rubles. It depends on the region and pharmacy chain.

No-shpa is an antispasmodic, the injection of which is effective when administered intravenously. To enter into a vein, the drug is pre-mixed with sodium chloride. Also, the drug is administered intramuscularly. The ampoule contains 40 mg of drotaverine hydrochloride. The instruction provides for the use of anesthetic medication after operations in the form of droppers. In this case, a prolonging effect of no-shpa is achieved. Next, we will consider when injections are prescribed, how quickly an intramuscular injection works, how to use ampoules for administration according to the instructions.

No-shpa in ampoules: composition of the injection

The medical product "" for intramuscular injection is produced in glass ampoules, in which there is 2 ml of injection solution. The volume of the active element in 1 ml is 20 mg of drotaverine. Injections can be made by intra-arterial, intravenous and intramuscular administration. The solution has a bright yellow-green color.

One 2 ml ampoule contains:

Active ingredient: drotaverine hydrochloride - 40.0 mg.
Excipients: sodium metabisulfite (E223), ethanol (E1510), water for injection.

pharmachologic effect

The drug gives excellent performance in the treatment of spastic syndrome of the gastrointestinal tract (gastrointestinal tract), urinary and genital areas, with spasms of the cerebral vessels of the brain, with depression and neurosis, Raynaud's disease.

However, care must be taken with prostate disease, because due to the relaxation of the smooth muscles of the bladder, problems with urination can occur.

Pharmacodynamics and pharmacokinetics

Rapidly and completely absorbed, both after oral administration and after intramuscular injection. It is highly bound to human plasma proteins (95-98%), especially albumin, gamma and beta globulins.

Drotaverine metabolizes in the liver for 8-10 hours. For 72 hours, drotaverine practically leaves the body, more than 50% of the feces. mainly in the form of excreted in the urine and about 30% - from metabolites, the original compound in the urine is not detected.

No-shpa in the form of injections: what is the medicine for?

Sometimes oral administration is undesirable for one reason or another. For example, due to lactose intolerance in the patient's body. Then he is given injections of the solution. It turns out a quick antispasmodic result. This form is effective for pancreatitis, pain in the back and internal organs.

If a person has signs of impaired glucose absorption, then a form of application of no-shpa in the form of injections is prescribed for them. Intravenously or intramuscularly, an anesthetic is prescribed for pancreatitis. After all, this type of ailment often manifests itself in the form of the development of signs of vomiting. Tablets with such symptoms will be simply useless. Due to the fact that injections have a rapid antispasmodic effect, many tend to use the medicine in this form, especially for pain in the back, stomach, kidneys, etc.

Indications for use

The instructions indicate the following indications for the use of No-shpa in injections:

cholelithiasis;
high blood pressure;
migraine with hypertension;
ulcerative lesions of the digestive tract;
inflammation of the mucous membrane of the stomach or peritoneum;
spasm of the esophagus;
inflammation of the mucous membrane of the small or large intestine;
inflammation of the wall of the gallbladder or mucous membrane of the renal pelvis;
infection of the bile ducts;
enlargement and inflammation of the anal papillae;
nephrolithiasis;
the presence of stones in the ureter;
inflammation of the bladder;
postoperative period;
injury.

For women, the medicine is prescribed for painful menstruation. In rare cases, a doctor will prescribe medicine for tumors to relieve pain.

Contraindications ⛔

The main contraindication to the use of this drug, like many other drugs, is the manifestation of severe disorders of the liver, kidneys, and heart, due to the insufficiency of their functions.
"No-shpa" is not prescribed during breastfeeding, since drotaverine and other representatives of this pharmacological category can penetrate into mother's milk.
The use of the drug is allowed from the age of 6, but only in tablet form, since studies on the effects of injection solutions have not been conducted, in accordance with which the use of the drug parenterally is contraindicated.
Taking the medication is contraindicated in the presence of high sensitivity to the active element or other substances from its composition.

It can be used only if certain precautions are observed with reduced blood pressure due to the high likelihood of collapse, as well as during pregnancy.

When is it used with caution?🚫

Like any pharmacological agent, the drug requires caution in use. The main reason why the tablet form can cause problems is lactose deficiency in the patient. Even if a person does not have personal intolerance to lactose itself, a negative effect on the digestive tract is quite possible, which can manifest itself as intestinal colic or vomiting.

With symptoms indicating poor absorption of sucrose, the active substances are administered to the patient with a syringe. No-shpa (solution for injection) is recommended for inflammation of the pancreas, when oral use of the drug is highly undesirable, because this disease often develops vomiting.

No-Shpa ampoules: instructions for use of injections for adults

No-shpa in ampoules: solution for intravenous and intramuscular administration (5 ampoules of 2 ml.)

The average daily dose of drotaverine in ampoules for an adult is from 40 to 240 mg. The drug is administered intramuscularly for 1-3 separate injections.

No-Shpa IV is administered to patients with stones in the biliary or urinary tract in acute colic. A single dose is from 40 to 80 mg (the solution should be administered slowly).

Dosage in injections

Injections are made 1 to 3 times a day. The instructions indicate the daily dosage for an adult and a child:

from 1 year to 6 years - 120 mg;
from 6 to 12 years old - 200 mg;
from 12 years old - 240 mg.

How to inject No-shpu in ampoules?

If it is contraindicated to drink tablets, prescribe a remedy in ampoules. Injected into a muscle or venous vessel. The dosage is indicated in the instructions. The required amount of liquid medicine is drawn into the syringe and the skin is treated at the injection site. Enter intramuscularly slowly. During the introduction, pain occurs. The syringe is not intended for reuse.

👨🏻‍⚕️ No-shpa intravenously can only be prescribed by the attending physician. In acute conditions, incl. against the background of colitis, pain quickly disappears after injection of 40-80 mg per day. You should not inject the medicine into a venous vessel on your own.

When does the No-shpa injection begin to act?

🕔 When using tablets, the result appears in 10-15 minutes. Injections significantly accelerate the decrease in the intensity of the pain syndrome, and relief comes within 5 minutes. It is thanks to this effect that injections have gained great popularity and distribution.

Side effects 🤒

Side effects occur with overdose. Frequent use of injections reduces the effectiveness of the drug, which forces you to increase the dose. But this leads to negative reactions of the body.

The instruction describes the following negative manifestations:

pressure reduction;
nausea and vomiting;
accelerated pulse;
skin rashes;
swelling at the injection site;
anaphylactic shock.

If the effect of the drug weakens, it is not necessary to increase the dose. This will cause overdose symptoms. You need to switch to another pain reliever.

Use during pregnancy and breastfeeding

For pregnant women, the form of the drug and the daily dose are selected individually. With increased tone of the muscles of the uterus in early pregnancy, the recommended dose varies from 80 to 240 mg / day.

No-Shpa in ampoules is usually used to prepare for childbirth. Drotaverine injections accelerate the process of opening the cervix. The drug is injected into the muscle at a dose of 40 mg. After a few hours, the injection is repeated if necessary.

drug interaction

When taken together with levodopa, the drug reduces the effect of the latter on the symptoms of Parkinson's disease, while increasing muscle stiffness and trembling (tremor). Shelf life 5 years.

Do not use the drug after the expiry date which is stated on the blister and carton.

special instructions

Before using No-shpa in injections for intramuscular injection, you need to know:

Clinical studies of the use of the drug in children are not presented.
With low blood pressure, the use of the drug requires caution.
With intravenous administration of drotaverine - due to the danger of loss of consciousness - the patient must lie down!
In case of hypersensitivity to sodium metabisulfite, parenteral use of the drug should be avoided.
Caution should be exercised when parenteral administration of the drug to pregnant women.
Influence on the ability to drive vehicles or other mechanisms
After parenteral, and especially intravenous administration of the drug, patients are advised to refrain from driving and working on machines.

Analogues

There are few of them, for the most part, produced by Russian manufacturers.

"Drotaverine". Identical to the described drug, although there are differences in bioavailability and bioequivalence. The release of "Drotaverin" is carried out by 9 Russian manufacturers.
"Drotaverin-Ellara" - produces LLC "Ellara".
"Nosh-Bra" - is produced in tablets and ampoules by the Russian pharmaceutical manufacturer Bryntsalov V.A.
"Spazmol" in tablet and injection forms is produced by the Russian company "Pharmstandard-UfaVITA".
"Spakovin" - ampoules and tablets. Produced by the Indian company "M.J. Biopharm".
An analogue of No-shpa is produced by the Belarusian Borisov ZMP.

No-shpa has a pronounced antispasmodic effect on the smooth muscles of the internal organs.

It is used for spasms of the gastrointestinal tract, biliary tract, angina pectoris, urolithiasis, peripheral vessels. The active ingredient is drotaverine.

The effect of taking this drug occurs within a few minutes. After half an hour, the phase of the maximum effect from taking this antispasmodic begins.

Can be used orally (tablets) and aprenterally (solution for injection).

Clinical and pharmacological group

Myotropic antispasmodic.

Terms of dispensing from pharmacies

Released without a doctor's prescription.

Prices

How much does No-shpa cost in pharmacies? The average price is at the level of 75 rubles.

Release form and composition

No-shpa tablets are small, round in color and yellow in color.

Tablet composition: 40 mg of drotaverine (in the form of hydrochloride), magnesium stearate, povidone, talc, corn starch, lactose (in the form of monohydrate).
Forte tablets have an identical composition. The only difference is the higher concentration of the active substance (80 mg/tab.).
The composition of No-Shpa in ampoules: drotaverine hydrochloride at a concentration of 20 mg / ml, 96% ethanol, sodium metabisulfite, water for injection.

No-shpa tablets are packaged in a blister of 6 and 24 pieces, as well as in glass bottles of 60 and 100 pieces. The cardboard pack contains one blister or bottle with the appropriate number of tablets, as well as instructions for using the drug.

Pharmacological effect

The main active ingredient of No-shpa is drotaverine hydrochloride, an antispasmodic that has a positive effect on the smooth muscles of the genitourinary and biliary tract, as well as the gastrointestinal tract. The substance contributes to the effective removal of puffiness, normalizes blood circulation and eliminates inflammation in muscle tissues.

The main advantage is the absence of a negative effect of the components of the drug on the functioning of the nervous system. After taking the tablets, the result is felt after 20 minutes, a greater effect is achieved after 1 hour. When the solution is administered intravenously - after 2-5 minutes, the maximum effect - after 30 minutes. Complete excretion of drotaverine from the body occurs 72 hours after ingestion.

Indications for use

What helps? No-shpa can be used both as a main and as an auxiliary therapeutic agent for a number of pathological conditions:

colic;
Spasm of the arteries;
spastic constipation;
Pyelite;
Tenesmus;
Proctitis;
Endarteritis;
Spasm of cerebral vessels.

In addition, No-shpa is used for certain conditions, to alleviate and relieve unpleasant symptoms.

No-Shpa for children

It is advisable to give medicine to children with cystitis and nephrolithiasis, sharp spasms of the duodenum or stomach, gastritis, enteritis, colitis, flatulence, constipation, spasm of peripheral arteries, high fever and severe headaches.

Tablets of 40 mg are prescribed for children from the age of six. Clinical studies of the safety and efficacy of Forte tablets in children have not been conducted.

Contraindications

Lactase deficiency, hereditary galactose intolerance, galactose-glucose malabsorption syndrome (tablets, due to the presence of lactose monohydrate in their composition);
Age up to 6 years (tablets);
The period of breastfeeding (due to the lack of necessary clinical data confirming the safety and efficacy of No-shpa for this group of patients);
Severe heart failure (low cardiac output syndrome);
severe liver or kidney failure;
Hypersensitivity to the components of the drug.

No-shpu should be used with caution against the background of arterial hypotension, in children and during pregnancy.

With intravenous administration of an injection solution, due to the risk of collapse, the patient must lie down.

Use during pregnancy and lactation

During pregnancy, it is possible to use the drug No-shpa only in cases where the expected benefit is several times greater than the possible danger to the development and health of the fetus. In this case, the dosage is selected strictly individually.

Dosage and method of application

The instructions for use indicate that when taking No-shpa without consulting a doctor, the recommended duration of taking the drug is usually 1-2 days. In cases where drotaverine is used as adjuvant therapy, the duration of treatment without consulting a doctor may be longer (2-3 days). If the pain syndrome persists, the patient should consult a doctor.

The effectiveness of the drug No-Shpa is three to four times higher than the effectiveness of Papaverine. In addition, the drug is characterized by 100% bioavailability. When taking a tablet, drotaverine is very quickly absorbed from the gastrointestinal tract: the half-absorption period of the substance is 12 minutes.

Dosages of No-shpa:

Adults are prescribed 1-2 tablets. at one time 2-3 times / day. The maximum daily dose is 6 tab. (corresponding to 240 mg).
Clinical studies with the use of drotaverine in children have not been conducted. In the case of the appointment of the drug No-shpa for children aged 6 to 12 years - 40 mg (1 tab.) 1-2 times / day, for children over the age of 12 years - 4 mg (1 tab.) 1- 4 times / day or 80 mg (2 tablets) 1-2 times / day. The maximum daily dose is 160 mg (4 tablets).

If the patient can easily self-diagnose the symptoms of his illness, because they are well known to him, the effectiveness of the treatment, namely the disappearance of pain, is also easily assessed by the patient. If within a few hours after taking the drug at the maximum single dose, there is a moderate decrease in pain or no decrease in pain, or if the pain does not significantly decrease after taking the maximum daily dose, it is recommended to consult a doctor.

When using a bottle with a polyethylene stopper equipped with a piece dispenser: before use, remove the protective strip from the top of the bottle and the sticker from the bottom of the bottle. Place the bottle in the palm of your hand so that the dosing hole on the bottom does not rest against the palm. Then press on the top of the vial, causing one tablet to fall out of the dosing hole on the bottom.

Side effects

Side effects against the background of the use of No-shpa are quite rare. The most common of these are:

feeling of increased heartbeat;
nausea;
itchy rash on the skin;
feeling of anxiety;
insomnia;
lowering blood pressure;
constipation;
headache;
angioedema;
dizziness.

Overdose

A significant excess of the recommended therapeutic dose of No-shpa tablets can lead to a violation of the rhythm of heart contractions (arrhythmia), as well as a violation of intracardiac conduction, up to a complete blockade with cardiac arrest.

Overdose treatment consists in washing the stomach, intestines, taking intestinal sorbents (activated charcoal), as well as conducting symptomatic therapy in a medical hospital.

special instructions

The composition of the 40 mg tablets includes 52 mg of lactose monohydrate, as a result of which complaints from the digestive system are possible in patients with lactose intolerance. This form is not intended for patients with lactase deficiency, galactosemia, or glucose/galactose malabsorption syndrome.

If any adverse reactions occur, the issue of driving vehicles and working with mechanisms requires individual consideration. In the event of dizziness after taking the drug, you should avoid engaging in potentially hazardous activities, such as driving vehicles and working with mechanisms.

drug interaction

PDE inhibitors, like papaverine, weaken the antiparkinsonian effect of levodopa. When prescribing the drug No-shpa simultaneously with levodopa, it is possible to increase rigidity and tremor.

With the simultaneous use of drotaverine with other antispasmodics, including m-anticholinergics, there is a mutual enhancement of the antispasmodic action.

No-shpa is a well-known, time-tested medicine. Almost all home first aid kits have this drug. Often parents are afraid to give this drug to young children. After all, the official instructions for use say that the medicine should not be given to children under 6 years of age. In what cases is No-shpa for children prescribed from an earlier age and how does it work?

No-shpa is an antispasmodic that effectively affects the muscle tissue of human internal organs and blood vessels. The drug relieves muscle tone, while expanding the vessels through which blood circulates.

The main substance is drotaverine. It is he who has a pronounced antispasmodic effect. After taking the medication, blood circulation normalizes, all organs and tissues are additionally saturated with oxygen. Painful spasms in this case are significantly reduced or completely disappear.

The drug is of the following types:

Tablet form;
Oval capsules;
Ampoule with liquid substance.

After taking No-shpa tablets, in children, the effect occurs within an hour. Intramuscular administration of the drug acts much faster - after 20 minutes.

Important! No-shpa injection solution should not be administered to persons under 18 years of age.

When can a doctor prescribe No-shpa for children?

Children under 6 years of age should be given medicine with great care. It is important to know that drotaverine, which is the main active ingredient of the drug, is artificially synthesized. In other words, this substance is not a natural ingredient. Therefore, the treatment of symptoms in children with No-shpa should only occur as prescribed by a doctor.

The drug is an excellent antispasmodic, but it does not have an analgesic effect like analgin and similar drugs. The drug has certain contraindications, which must also be taken into account when treating children.

Usually the medicine is prescribed to small patients in such cases:

: high temperature with cold extremities. In this case, No-shpa can relieve vasospasm, dilate blood vessels, improve blood circulation;
Spasms with or stenosis, causing severe coughing;
Spasms causing headaches;
Intestinal or renal colic;
Excessive painful gas formation;
Spasm of smooth muscles with pyelitis;
Spasms in colitis or gastritis.

Important! No-shpa has only a symptomatic effect, that is, it eliminates the spasm that caused the pain, but it does not treat the very cause of the spasm. Therefore, No-shpa is an adjuvant that should be prescribed along with the main medicine.

Contraindications

Nosh-pa for the treatment of young children should be used with caution, mindful of possible contraindications. The drug should not be given to children in such cases:

Children's age up to 1 year;

Reduced blood pressure in a child;

Individual intolerance to the children's organism of drotaverine;

Bronchial asthma;

Vascular disease (atherosclerosis);

Suspicion of a baby;

Suspicion of appendicitis;

Liver or kidney failure.

Important! In some cases, a doctor may prescribe a few drops of No-Shpa ampoule for an infant under 1 year of age for acute spasmolytic pain or white fever.

After taking the medicine, the child may experience some side effects:

Indigestion. Some time after the child has taken the drug, he may experience nausea, often accompanied by vomiting. It is also possible indigestion, constipation, increased separation of gases.

From the side of the cardiovascular system, problems after taking the drug are rare. But if a child has tachycardia or a sharp drop in pressure, which is expressed in drowsiness and lethargy, then the drug should be stopped.

No-shpa can cause dizziness and insomnia in a child. In such cases, it is also necessary to abandon the use of the drug.

Allergy. No-shpa rarely causes allergic reactions, but sometimes the baby may experience sneezing, a rash on the body.

In case of side effects, it is recommended to stop taking the drug immediately.

Dosage of medication for children

In pediatrics, the medicine is prescribed to children who have reached the age of one. The use of the drug in children under 1 year of age can disrupt the cardiovascular system. However, sometimes the medication is prescribed in small doses to newborns. The drug effectively relieves spasms and colic in infants. If the child is breast-fed, it is enough for the mother to take 1 No-shpa tablet before feeding. The active active substance through mother's milk in minimal quantities will enter the body of the newborn, relieving pain, spasm and colic. With artificial feeding, the baby is allowed to give a strictly defined dosage of the medication as prescribed by the doctor, dissolved in boiled water.

The amount of the drug that needs to be given to the child depends on two factors: the form of release of the drug No-shpa and the age of the child.

Children from 1 year to 6 years. Usually, this age group is prescribed the drug with extreme caution, 1/3 tablet 3 to 6 times a day, depending on the severity of the condition. Taking the drug No-shpa for children in this group should not exceed 2 tablets per day;

Children from 6 to 12 years old. 1/2 tablet 3 to 8 times a day, depending on the severity of the condition. Taking the drug No-shpa for children in this group should not exceed 4 tablets per day;

Children over 12 years old. 1 tablet 3 to 5 times a day, depending on the severity of the condition. Taking the drug No-shpa for children in this group should not exceed 5 tablets per day.

No-shpa is an effective remedy that relieves various spasms. Use this drug to treat babies with extreme caution and only when absolutely necessary. Children from the age of 6 can be given the drug No-shpa without fear. However, it should be remembered that it is possible to give a child medicine without a doctor's prescription for no more than two days.

Remember that only a doctor can make a correct diagnosis, do not self-medicate without consultation and diagnosis by a qualified doctor.