What helps troxerutin ointment. Troxerutin Vetprom - a highly effective venotonic drug for external use Troxerutin gel instructions for use vetprom


p> Active substance: troxerutin 20 mg.

Indications for use Troxerutin Vetprom

  • Chronic venous insufficiency with manifestations such as static heaviness in the legs, leg ulcers, trophic skin lesions;
  • varicose veins, superficial thrombophlebitis, periphlebitis, phlebothrombosis, varicose dermatitis, post-thrombotic syndrome, hemorrhoids, post-traumatic edema and hematomas, hemorrhagic diathesis with increased capillary permeability, capillary toxicosis (including with measles, scarlet fever, influenza), diabetic microangiopathy, retinopathy, vascular side effects of radiation therapy;
  • as a prophylactic after operations on the veins.

Contraindications to the use of Troxerutin Vetprom

Hypersensitivity, peptic ulcer of the stomach and duodenum, chronic gastritis (in the acute phase).

Troxerutin is applied topically. A 2% gel is used locally, which is applied evenly in a thin layer in the morning and evening on the affected area from the distal to the proximal part, gently rubbing until completely absorbed into the skin. The gel can also be applied under an occlusive dressing.

The use of Troxerutin Vetprom during pregnancy and lactation

It is contraindicated in the first trimester of pregnancy and while breastfeeding; in the second and third trimesters of pregnancy, it can be used only as directed by a doctor.

pharmachologic effect

Troxerutin is a venotonic, angioprotective agent, bioflavonoid. It reduces the permeability and fragility of capillaries, strengthens the vascular wall, improves microcirculation, and has a decongestant effect. Participates in redox processes, blocks hyaluronic acid of cell membranes. Increases the density of the vascular wall, reduces the exudation of the liquid part of the plasma and diapedesis of blood cells. Reduces inflammation in the vascular wall by limiting the adhesion of platelets to its surface. The use of troxerutin is possible both at the initial and late stages of the treatment of chronic venous insufficiency, it is possible to use it as one of the components of complex treatment.

The description is up to date 18.01.2015
  • Latin name: Troxerutin
  • ATX code: C05CA04
  • Active substance: Troxerutin (Troxerutin)
  • Manufacturer: OJSC “Biochemist”, Russian Federation Sopharma AD, Adifarm EAT, Bulgaria PJSC FF “Darnitsa”, PJSC “Chemical Plant “Krasnaya Zvezda”, Ukraine

Compound

The composition of Troxerutin, produced in the form of capsules, includes 300 mg troxerutin (Troxerutin) and excipient substances: lactose monohydrate (Lactose monohydrate), colloidal silicon dioxide (Silicon dioxide colloidal), macrogol 6000 (Macrogol 6000), magnesium stearate (Magnesium stearate).

For the manufacture of capsules are used: titanium dioxide (Titanium dioxide), gelatin (Gelatin), dyes (quinoline yellow - 0.75%, sunset yellow - 0.0059%).

Gel composition: troxerutin (Troxerutin) at a concentration of 20 mg / gram, methyl parahydroxybenzoate (E218; Methyl parahydroxybenzoate), (Carbomer), triethanolamine (Triethanolamine), disodium edetate (Edetate disodium), purified water (Aqua purificata).

Release form

The medicine is available in the form:

  • gel for external use in aluminum tubes with a volume of 25, 35, 40, 50 and 100 grams;
  • capsules, packaged in 10 pieces in blisters, 5 blisters in one carton.

pharmachologic effect

The drug belongs to the pharmacological group of drugs that have antispasmodic action , promote relaxation smooth muscle of blood vessels and others internal organs .

Pharmacodynamics and pharmacokinetics

The tool enhances venous wall tone and reduces their extensibility, thereby eliminating venous congestion and preventing development, reduces the intensity of the inflammatory process, has membrane stabilizing and capillary protective effects .

The drug is characterized by P-vitamin activity, stimulates the processes of elimination of products from tissues, does not have an embryotoxic effect, does not cause mutations and developmental disorders of the fetus.

After oral administration, it is well absorbed from the digestive tract. The plasma concentration of the substance reaches its peak values ​​2-8 hours after taking the capsule. The second peak occurs after about 30 hours.

Troxerutin is almost completely eliminated from the body within 24 hours after ingestion, while about 75-80% of the substance is excreted by the liver, the remaining 20-25% - kidneys .

When applied topically, absorption of the substance into the systemic circulation does not occur, however, the drug penetrates well into adjacent tissues through the skin.

Indications for use: from what Troxerutin is prescribed

The use of Troxerutin tablets and gel is advisable:

  • with accompanying trophic skin lesions , static weight in the legs, leg ulcers, chronic venous insufficiency ;
  • at varicose disease (including when);
  • at post-thrombophlebitic syndrome ;
  • at peri- and ;
  • at ;
  • at hemorrhagic diathesis , which are characterized by increased permeability of capillary walls;
  • at post-traumatic hematomas and tissue swelling ;
  • at Schonlein-Henoch disease (hemorrhagic capillarotoxicosis ; including at , or );
  • at diabetic retino- and microangiopathy ;
  • with vascular effects that developed against the background.

As a prophylactic, the drug can be used after operations on the veins.

Contraindications

Contraindications for use are:

  • increased sensitivity to the components of the drug;
  • chronic gastritis in the acute phase;
  • age up to 15 years;
  • first trimester pregnancy ;

The drug is prescribed with caution in case of insufficiency of kidney function (if necessary, long-term use).

Side effects

The use of the drug may be accompanied by the following side effects:

  • irritation mucosa of the digestive tract ;
  • , which are expressed in the form of rashes on the skin and.

Instructions for use Troxerutin

Capsules Troxerutin: instructions for use

Troxerutin tablets are taken with meals, swallowed whole. In accordance with the standard treatment regimen, oral administration of 0.9 grams of troxerutin per day (one tablet three times a day) is prescribed. If the medicine is used as a maintenance agent, it should be taken one capsule twice a day.

The full course of treatment lasts from 3 to 4 weeks. The expediency of longer use is determined individually by the attending physician.

Instructions for preparations of different manufacturers may differ slightly from each other.

For example, capsules Troxerutin Zentiva take according to the above scheme, and the capsules Troxerutin Vramed at the initial stages of treatment, take one 2 or 3 times a day, after which they switch to maintenance treatment, which involves taking one capsule per day.

Treatment with Troxerutin-MIC begin with intravenous or intramuscular injection of 0.5 grams of troxerutin in the form of an injection solution. The procedures are repeated every other day, while it is recommended to make at least 5 injections of the drug.

After that, they switch to taking dosage forms for oral administration. The starting dose is 0.6-0.9 grams per day, the maintenance dose is 0.3 grams per day. The course of treatment is from 2 to 4 weeks, if there are no other indications.

Gel Troxerutin: instructions for use

Ointment Troxerutin is a remedy for external use. It should be applied twice a day (in the morning and evening hours), in a thin layer, evenly distributing on the skin of the painful area from the distal (most remote) to the proximal (closest) part of it and lightly massaging until completely absorbed.

The dose is determined by the area of ​​the damaged surface, but should not exceed 1-2 grams (this corresponds to approximately 3-4 cm of gel). After applying the medicine to the affected area of ​​the skin, you can apply an occlusive dressing.

Unlike capsules, the treatment regimen using gels from various manufacturers is no different, that is, instructions for using the ointment Troxerutin Vramed identical to instructions, for example, Troxerutina Vetprom .

Overdose

To date, no cases of overdose of Troxerutin have been reported.

In case of accidental ingestion of the drug in the form of a gel or capsules at a dose significantly higher than the therapeutic dose, a gastric lavage procedure should be carried out and an enterosorbent should be taken.

Interaction

The drug potentiates the effect on the structure and permeability parameters walls of blood vessels .

Terms of sale

Non-prescription drug.

Storage conditions

Store in a place protected from direct sunlight. The optimal temperature regime for storing the gel is 8-15°C, for capsules - 15-25°C.

Best before date

Gel usable for 2 years, capsules for 5 years from the date of issue.

special instructions

Gel and capsules Troxerutin are allowed to be used as one of the components of complex therapy. Yes, therapy. deep vein thrombosis or superficial does not preclude the need for antithrombotic and anti-inflammatory drugs .

There is no experience in the use of the drug for the treatment of patients under 15 years of age.

Analogues

Coincidence in the ATX code of the 4th level:

It should be remembered that the composition is not suitable for relieving swelling of the legs, which is associated with kidney dysfunction , liver and heart diseases . Before using the drug and the use of concomitant therapeutic measures, you should always consult with your doctor.

Troxerutin price

The price of Troxerutin gel starts from 30 rubles, the price of Troxerutin capsules - from 100 rubles.

In Ukrainian pharmacies, the price of Troxerutin tablets is from 59 UAH, the price of Troxerutin ointment is from 11 UAH.

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Pharmacy Dialog

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In this medical article, you can get acquainted with the drug Troxerutin. The instructions for use will explain in which cases you can take tablets, gel or ointment, what the medicine helps with, what are the indications for use, contraindications and side effects. The annotation presents the form of release of the drug and its composition.

In the article, doctors and consumers can only leave real reviews about Troxerutin, from which you can find out if the medicine helped in the treatment of varicose veins, hemorrhoids and bruises in adults and children, for which it is also prescribed. The instructions list analogues of Troxerutin, drug prices in pharmacies, as well as its use during pregnancy.

A drug with venotonic and angioprotective properties is Troxerutin. Instructions for use suggest taking capsules or tablets 300 mg Zentiva, Vramed and VetProm, gel or ointment 2% for hemorrhoids and varicose veins.

Release form and composition

The drug is produced in the following dosage forms:

  • Gel for external use 2% (sometimes erroneously called ointment) Vramed and VetProm.
  • Capsules 300 mg (sometimes erroneously called tablets) Zentiva, Vramed and VetProm.

The gel is packed in aluminum tubes with a volume of 25 g, a detailed annotation with a description is included in the pack with the preparation. The gel is odorless and colorless, 100 g of the drug contains 2 g of the active active substance Troxerutin, disodium edetate, benzalkonium sodium chloride hydroxide solution, purified water act as auxiliary components.

Capsules are hard, gelatinous, yellow, packed in blisters of 10 pieces (5-10) in a carton with instructions.

Each capsule of the drug contains 300 mg of the active ingredient - Troxerutin, the drug also contains a number of auxiliary components: titanium dioxide, dye, gelatin, lactose monohydrate, magnesium stearate.

pharmachologic effect

The active ingredient of Troxerutin Vetprom is a bioflavonoid with venotonic and angioprotective effects. Reduces fragility and permeability of capillaries, increases their tone, strengthens the walls of blood vessels, enhances microcirculation and has a decongestant effect.

In addition, it reduces the exudation of the liquid part of the plasma, as well as diapedesis of blood cells. Takes part in redox processes, blocks hyaluronidase and stabilizes hyaluronic acid of cell membranes. Under the influence of troxerutin, inflammation in the vascular wall decreases, and platelet adhesion to its surface is limited.

With topical application of the gel, its active substance quickly penetrates the epidermis. Within 30 minutes it is found in the dermis, after 2-5 hours in the subcutaneous fat.

Indications for use

What helps Troxerutin? The use of tablets and gel is advisable for:

  • post-thrombophlebitic syndrome;
  • post-traumatic hematomas and tissue swelling;
  • hemorrhoids;
  • peri- and thrombophlebitis;
  • accompanied by trophic skin lesions, static heaviness in the legs, leg ulcers, chronic venous insufficiency;
  • Schonlein-Genoch disease (hemorrhagic capillary toxicosis; including influenza, measles or scarlet fever);
  • vascular effects developed on the background of radiation therapy;
  • diabetic retino- and microangiopathy;
  • hemorrhagic diathesis, which are characterized by increased permeability of capillary walls;
  • varicose veins (including during pregnancy).

As a prophylactic, the drug can be used after operations on the veins.

Instructions for use

Troxerutin gel

Outwardly: the gel is applied evenly in a thin layer in the morning and evening on the skin over the painful area and lightly massaged until completely absorbed. The dose of the drug depends on the area of ​​the damaged surface, but should not exceed 3-4 cm of gel (1.5-2 g). The gel can be applied under an occlusive dressing.

Capsules Troxerutin

Designed for oral administration. The drug is taken with food, immediately swallowing, drinking the necessary amount of water.

The dose of the drug is determined by the doctor individually and at the initial stage of therapy is 300 mg at a time and 900 mg per day, divided into 3 times. A noticeable therapeutic effect of the drug is observed approximately 2 weeks from the start of therapy, after which the daily dose of the drug is reduced to 600 mg (300 mg 2 times a day).

The duration of the course of therapy with the drug is on average 1 month, but may vary on an individual basis as directed by the doctor.

Contraindications

Contraindications for use are:

  • age up to 15 years;
  • chronic gastritis in the acute phase;
  • first trimester of pregnancy;
  • duodenal ulcer;
  • hypersensitivity to the components of the drug;
  • breast-feeding;
  • stomach ulcer.

The drug is prescribed with caution in case of insufficiency of kidney function (if necessary, long-term use).

Side effects

The drug Troxerutin is well tolerated by patients, but in some cases, with increased individual sensitivity to the components of the capsule, negative reactions may develop:

  • allergic reactions - a feeling of heat in the face, a rash on the skin, redness of the skin, urticaria;
  • on the part of the digestive system - increased thirst, lack of appetite, nausea, vomiting, impaired stool;
  • from the nervous system - headaches, psychomotor overexcitation, dizziness.

If side effects occur, stop treatment with the drug and seek medical help.

Children, during pregnancy and lactation

Taking the drug Troxerutin is contraindicated in the 1st trimester of pregnancy. The drug can be used in the 2nd and 3rd trimester of pregnancy, as well as during lactation. The possibility of using the drug during pregnancy is determined by the doctor. There is no experience of using the drug in children under the age of 15 years.

special instructions

Gel and capsules Troxerutin are allowed to be used as one of the components of complex therapy. Thus, the therapy of deep vein thrombosis or superficial thrombophlebitis does not exclude the need to prescribe antithrombotic and anti-inflammatory drugs.

There is no experience in the use of the drug for the treatment of patients under 15 years of age.

drug interaction

In order to prevent the development of side effects from the digestive tract, Troxerutin capsules are not recommended to be administered to patients simultaneously with ascorbic acid. Vitamin C enhances the therapeutic effect of Troxerutin, which can cause nausea, vomiting, headaches, and allergic reactions.

Capsules can be combined with the use of the drug in the form of a gel - this will enhance the therapeutic effect of the drug.

Troxerutin's analogs

According to the structure, analogues are determined:

  1. Troxevenol.
  2. Troxevasin.
  3. Troxerutin VetProm (Vramed; Zentiva; Lechiva; MIK).

For the treatment of varicose veins, analogues are prescribed:

  1. Vasoket.
  2. Emeran.
  3. Venoplant.
  4. Aescusan.
  5. Stugeron.
  6. Indovazin.
  7. Ellon gel.
  8. Hepatrombin.
  9. Fibro Wayne.
  10. Reparil gel H.
  11. Antistax Gel.
  12. Viatromb.
  13. Agapurin retard.
  14. Anavenol.
  15. Venen.
  16. Ralofect.
  17. Phlebodia 600.
  18. Venolife.
  19. Vasonite.
  20. Stilamine.
  21. Lyoton 1000.
  22. Antistax.
  23. Agapurin.
  24. Cyclo 3.
  25. AngioNorm.
  26. Ultralan.
  27. Tsinnasan.
  28. Venoruton.
  29. Pentoxifylline.
  30. Aesculus compositum.
  31. Rutin.
  32. Thrombovar.
  33. Heparoid Lechiva.

Holiday conditions and price

The average cost of Troxerutin (gel 2% 40 g) in Moscow is 25 rubles. The price of 50 capsules of 300 mg is 168 rubles. Released without a prescription.

Store in a dry place, away from light, at a temperature not exceeding 25 °C. Keep away from children. Shelf life - 5 years.

Read also the instructions for use of a close analogue of Troxevasin.

By clicking on the links, you can find out which analogues are used to treat diseases: varicose veins, varicose veins, hematoma, hemorrhoids, dermatitis, diabetic angiopathy, periphlebitis, post-thrombotic syndrome, retinopathy, bruise, thrombophlebitis, trophic ulcer, chronic venous insufficiency

instrukciya-po-primeneniyu.ru

Troxerutin

Troxerutin gel is a venotonic external agent that strengthens the walls of blood vessels.

The drug is used in the complex treatment of varicose veins and chronic venous insufficiency. And in proctological practice, it is used to eliminate painful hemorrhoids. The gel is characterized by a pronounced anti-inflammatory and angioprotective activity.

The drug is prescribed to patients with the aim of stopping edema, normalizing blood circulation, and relieving pain. It is affordable, inexpensive and very convenient for home therapy. But with prolonged and frequent use, the risk of side effects increases. The phlebologist after the examination will determine the safe dosing regimen and the optimal duration of treatment.

Clinical and pharmacological group

Venotonic drug for external use.

Terms of sale from pharmacies

Can be bought without a doctor's prescription.

Price

How much does Troxerutin gel cost in pharmacies? The average price is at the level of 65 rubles.

Composition and form of release

Troxerutin is available in the form of a gel for external application and capsules for oral administration. The combination of these two therapeutic forms of the drug mutually enhances the positive therapeutic effect of each other.

The active substance of the gel is troxerutin, which is a flavonoid of the plant substance rutin. The composition of 1 gram of the drug includes 20 mg of the active ingredient.

Pharmacological effect

The composition of the gel and capsules (tablets) includes troxerutin, which has phleboprotective activity. The pharmacological action of the drug is identical to the routine from the vitamin P group. The active ingredient takes part in the redox reactions that occur in the human body. It inhibits the enzyme hyaluronidase, which blocks the biosynthesis of hyaluronic acid. By reducing the fragility and permeability of capillaries increases the density of blood vessels.

Troxerutin gel is also characterized by the following therapeutic properties:

  • reduction of exudation of plasma fluid;
  • relief of inflammatory processes occurring in the walls of the veins;
  • limiting the adsorption of platelets to the walls of blood vessels, reducing their lumen;
  • preventing the exit of blood cells through the walls of capillaries and small veins.

Troxerutin prevents the formation of free radicals. It is these compounds that are responsible for cell damage and further tissue destruction. At the initial stage of the pathology, doctors prescribe the drug as monotherapy. This helps to reduce the pharmacological burden on the human body. Improving lymphatic drainage function allows the use of the drug in the severe stage of the disease. In this case, it is combined with Troxerutin capsules or drugs with diosmin.

Indications for use

The listed pharmacological effects of the drug allow the use of the gel in the treatment of venous insufficiency, trophic ulcers, as well as in the complex treatment of diseases that provoke an increase in vascular permeability. The gel allows you to quickly and effectively eliminate bruises, bruises, hematomas, sprains. Indications for the use of the drug troxerutin are as follows:

  1. Capillarotoxicosis, which occurs with influenza, scarlet fever, measles.
  2. Hemorrhagic diathesis, which is accompanied by impaired capillary permeability; diabetic retinopathy.
  3. The drug is also used in the treatment of trophic ulcers and dermatitis provoked by varicose veins.
  4. Elimination of manifestations of the chronic form of venous insufficiency: pain syndrome, edema, feelings of heaviness and fatigue, the development of seizures, the formation of a vascular pattern.
  5. Comprehensive treatment of varicose veins (including during childbearing), superficial thrombophlebitis, phlebothrombosis, postphlebilitic syndrome.
  6. Treatment of soft tissue bruises, which are accompanied by the formation of hematomas and edema.

The medicine in the form of a gel is used in the recovery period after surgery (performing the sclerotherapy procedure) as an auxiliary element of therapy in order to provide a preventive effect.

Contraindications

  • Children and adolescents up to 18 years of age;
  • hypersensitivity to the components of the drug.

Additionally for capsules:

  • I trimester of pregnancy and lactation;
  • peptic ulcer of the duodenum, stomach, chronic gastritis in the acute stage.

An additional contraindication for Troxerutin in the form of a gel is a violation of the integrity of the skin.

In chronic renal failure, the drug should be used with extreme caution (with prolonged use).

Appointment during pregnancy and lactation

The drug can be prescribed to patients only in the 2nd and 3rd trimesters of pregnancy. The doctor correlates the risk for intrauterine development of the fetus and the benefit to the mother. During childbearing, Troxerutin gel is used for application to the skin in minimal dosages. It is strictly prohibited for use during breastfeeding.

Dosage and method of application

As indicated in the instructions for use, Troxerutin gel is applied evenly in a thin layer in the morning and evening on the skin over the painful area and gently massaged until completely absorbed. The dose of the drug depends on the area of ​​the damaged surface, but should not exceed 3-4 cm of gel (1.5-2 g).

The gel can be applied under an occlusive dressing.

Adverse reactions

The use of the gel can provoke side effects such as allergic reactions in the form of itching, redness, burning. Since the drug does not penetrate into the general circulation, it does not adversely affect other organs.

In most cases, the drug is well tolerated by all categories of patients, and the resulting adverse reactions are temporary, transient.

Overdose

To date, no cases of overdose of Troxerutin have been reported.

In case of accidental ingestion of the drug in the form of a gel or capsules at a dose significantly higher than the therapeutic dose, a gastric lavage procedure should be carried out and an enterosorbent should be taken.

There is no specific antidote.

special instructions

Before you start using the drug, read the special instructions:

  1. The gel should only be applied to an undamaged surface.
  2. In the treatment of deep vein thrombosis or superficial thrombophlebitis, the use of Troxerutin capsules does not exclude the appointment of antithrombotic and anti-inflammatory drugs.
  3. For the treatment of edema caused by concomitant diseases of the kidneys, liver and heart, the use of capsules is ineffective.
  4. In case of unintentional ingestion of the drug, nausea, vomiting, burning sensation in the mouth, salivation are acceptable. In such a case, it is recommended to wash the stomach and oral cavity, if necessary, symptomatic treatment.
  5. If the gel gets into the eyes, mucous membranes and open wounds, local irritation is noted - burning, lacrimation, pain, hyperemia. In this case, it is necessary to wash off the agent with a large volume of isotonic sodium chloride solution or distilled water until a significant decrease in the severity or complete disappearance of these reactions.
  6. Do not exceed the recommended doses and maximum duration of treatment with self-administration of the drug.
  7. If during the use of the drug the severity of the symptoms of the disease does not decrease or the symptoms worsen, you should immediately consult a specialist.
  8. It is required to avoid getting the gel in the eyes, mucous membranes and open wounds.
  9. The gel is used in combination with ascorbic acid to enhance its effect in conditions characterized by increased vascular permeability (including influenza, scarlet fever, measles and allergic reactions).

Interaction with other drugs

There are no data on the adverse interaction of troxerutin in the form of a gel with other drugs.

Reviews

We suggest that you read the reviews of people who used Troxerutin:

  1. Nataliya. Gel "Troxerutin" is my salvation. Especially now, in bad weather, when he twists his legs at night, especially in bad weather. After operations for varicose veins, I settled on this particular drug. Efficiency - on a par with Troxevasin and Lyoton. And the price is much lower. Yes, it also helps very well with swelling of the legs and arms of a different nature. The main thing to remember is not to rub, but to apply, lightly spreading, until absorbed. And your legs and arms will thank you. I recommend to all! The only thing is that the tube is usually incomplete ... although the packaging is factory-made.
  2. Sasha. My mom bought troxerutin capsules and gel as she has varicose veins. I make her undergo a course of treatment in order to maintain a more or less normal condition of the veins and not start the sore. Her legs do not hurt, but they are all dotted with a fine network of blood vessels. I don’t want to have severe thrombosis later and nothing helps at all. So from time to time she drinks capsules and smears her legs with troxerutin gel
  3. Faith. I have been using Troxerutin for two years already - before pregnancy and after pregnancy. Varicose veins raged after childbirth. To be honest, I don’t have much result from the gel. I just used it before pregnancy as a cheap option for prevention, and after it out of a budgetary habit. The veins do not hurt and do not increase, maybe it somehow acts internally, but the appearance of the legs has not changed. I am waiting for the end of lactation, I will try to combine it with the internal use of Troxerutin tablets. I know that complex treatment is much more productive. Troxerutin gel is good at an inexpensive price, a tube is enough for two weeks.

Analogues

Structural analogues for the active substance:

  • Troxevasin;
  • Troxevenol;
  • Troxerutin VetProm;
  • Troxerutin Vramed;
  • Troxerutin Zentiva;
  • Troxerutin Lechiva;
  • Troxerutin MIC.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

The medication should be stored in a dry and dark place out of the reach of children. Storage temperature should not exceed 25 degrees Celsius.

The period during which the drug is suitable is 5 years from the date of manufacture. It is forbidden to use the drug after the expiration of the period indicated on the package.

simptomy-treatment.net

What helps Ointment Troxerutin - a venotonic drug

Ointment Troxerutin strengthens and tones the walls of blood vessels (it is an angioprotector). Thanks to these properties, normal blood flow is restored, congestion is reduced.

Attention! If there is damage on the skin, pustular rashes - the drug is not used. Ointment is also contraindicated for children under 15 years of age, patients with diseases of the heart, kidneys and liver. Pregnant and lactating women should take the ointment after consulting a specialist.

Troxerutin ointment helps with edema, thrombosis, varicose veins, vascular fragility and other vascular pathologies, including hemorrhoids and chronic venous insufficiency.

The tool is not prescribed in the presence of such contraindications:

  • Individual intolerance to the components included in the composition;
  • Swelling of the lower extremities, which occurs when the kidneys, liver, heart are disturbed;
  • Children under 15;
  • Violation of the integrity of the skin;
  • Use with caution during pregnancy and lactation.

Important! Ointment Troxerutin is well tolerated by the skin, however, in rare cases, side effects may develop, which are expressed by irritation, rash, itching.

Composition and properties

The main active ingredient of the ointment is the troxerutin component. This substance is a flavonoid of plant origin, which is obtained from rutin.

Troxerutin has a wide range of effects and has a number of positive properties:

A source:

Gel Troxerutin for hemorrhoids

There are thousands of drugs on the market for the treatment of hemorrhoids. They differ in the mechanism of action, degree of effectiveness, and, most importantly, price. This article will focus on the drug of the bioflavonoid group - Troxerutin.

How does this substance work? What are the indications and contraindications for its use? What are the advantages of this drug? We will try to answer all questions in detail.

Mechanism of action

This drug is a synthetic analogue of rutin, a natural substance that has an effect on blood vessels. If we compare rutin with diosmin, then the latter will be more effective. However, Troxerutin for hemorrhoids continues to be actively used. This is due to the affordable price of drugs in this class.

In the body, Troxerutin affects all types of vessels: arterial, venous and lymphatic. It reduces inflammation of the venous wall, stimulates vascular tone, improves the functionality of the shallow channel (capillaries), and reduces arterial permeability.

Due to this, its actions are implemented:

  • removal of edema;
  • resorption of blood clots;
  • elimination of venous congestion;
  • pain reduction.

Dosage forms

Many companies produce preparations based on Troxerutin under different trade names. Their differences are minimal. But dosage forms deserve special attention. After all, Troxerutin is available both in capsules and in the form of external agents - ointments and gels.

Capsules Troxerutin 300 mg are administered orally. The therapeutic dose of the drug is 900 mg, i.e. 3 capsules per day. With a decrease in the severity of symptoms, it is possible to use 2 capsules of this drug. The course of treatment lasts an average of 1 month. In case of recurrence of the disease, it is possible to take the drug again with a break of 2 months.

Of the local preparations, Troxevasin gel and Troxerutin gel are the most common. Some companies combine the active substance with other components. There is an ointment based on Troxerutin and bodyagi.

Such funds are effective for edematous nodes, as well as for hemorrhoidal thrombosis.

The convenience of the dosage form is that it is applied directly to the pathological focus and avoids unwanted systemic effects.

Indications for use

Troxerutin is used quite often. Capsules can be used for all types of exacerbations:

  • bleeding hemorrhoids;
  • inflammation of the nodes;
  • thrombosis of "cones".

Also, the drug is used without exacerbation for preventive purposes.

The ointment is used externally. It is usually used in the complex therapy of thrombosis. The gel is easy to apply on the outer and inner bumps. Under its influence, swelling and pain quickly disappear. Also, the ointment can be used after minimally invasive operations to accelerate recovery processes.

How to use?

Capsules are used in courses. During an exacerbation, the recommended dose is 3-5 capsules per day. Taking the medicine at this dosage lasts one week. After that, proctologists recommend reducing the dose to 2 capsules per day and continuing to take the drug for another 3 weeks. If necessary, the course of treatment is repeated after 2-3 months.

How to use Troxerutin gel? This local drug is applied directly to the pathological focus. The ointment is applied twice a day (morning and evening). Before use, it is necessary to take a hygienic shower; for internal localization, it is recommended to make a microclyster. The ointment is used only on cleansed skin and mucous membranes.

Apply the ointment until completely absorbed. The gel is taken in a small amount of about 1.5-2g. The duration of the course of treatment is about 10 days.

When is the drug contraindicated?

The use of capsules is prohibited during pregnancy (1 trimester), with ulcers and exacerbation of chronic gastritis, with renal failure. The drug is not used in pediatric practice due to toxic effects on the intestinal mucosa.

The gel should not be used for irritation and damage to the skin. It is also contraindicated in case of hypersensitivity to the components of the drug.

Side effects

Like any medicine, Troxerutin has a number of side effects. The patient needs to be attentive to himself during the course of treatment. It is necessary to inform the doctor about the appearance of the first symptoms. We list the undesirable effects of Troxerutin:

  • headache. It is due to the expansion of the venous vessels of the brain;
  • dyspepsia. Troxerutin irritates the mucous membrane of the stomach and intestines. Sometimes it is required to combine the drug with gastroprotectors (omeprazole);
  • dermatitis. They are caused by the use of ointment;
  • urticaria and rash appear with an allergic reaction to the components of the drug.

So, Troxerutin is a popular and affordable remedy for the treatment of hemorrhoids. Its action is weaker than modern phlebotropic drugs. A huge plus is the presence of an external form of Troxerutin. Its use helps to minimize the risk of complications and avoid unwanted systemic effects. Troxerutin should be used in combination with other hemorrhoid drugs.

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Treatment of hemorrhoids

In domestic medicine, Troxerutin has been prescribed for hemorrhoids for a long time. Almost every third patient who turned to doctors with this problem was prescribed this venotonic agent.

And there are many explanations for this: the drug really has a strong anti-inflammatory and anti-edematous effect.

In addition, Troxerutin also has antioxidant properties and does not have a mutagenic effect.

Today it is generally accepted that there are more effective means that have fewer contraindications. Nevertheless, this venotonic and angioprotector continues to receive good reviews from patients and doctors. It is relatively cheap and is included in the Russian list of vital drugs.

Indications

Troxerutin is used to treat various venous diseases, not only hemorrhoids. It relieves inflammation, swelling, increases the elasticity of blood vessels and reduces their permeability, and also promotes the removal of metabolic products from tissues.

Application:

  • varicose veins in the legs;
  • inflammation of hemorrhoids;
  • varicose dermatitis;
  • pain after injuries, dislocations, sprains;
  • phlebothrombosis;
  • microangiopathy;
  • increased capillary permeability in infectious diseases;
  • postoperative prevention of venous diseases.

If the patient is using the gel, the drug is rapidly absorbed through the skin. And the capsules are well absorbed in the stomach and intestines, already a day after ingestion, there are almost no traces of the drug left in the body (excreted by the liver and kidneys).

See also: What is the most common blood type in Russia and the world

Contraindications

Usually Troxerutin and its analogues (Troxevanol, Troxevasin and others) are well tolerated by patients, but in some cases headaches, stool disorders, and when applied externally, various rashes and redness are possible. It should be borne in mind that the drug has contraindications:

  • hypersensitivity to active substances;
  • exacerbation of gastritis;
  • peptic ulcer of the stomach and duodenum;
  • first trimester of pregnancy;
  • breast-feeding (during treatment with the gel, it is not necessary to interrupt feeding, since the agent slightly penetrates into the blood and accumulates more in the tissues).

It is also necessary to take the drug with caution to people with kidney disease and children under the age of fifteen.

Release form and instructions for use

Reviews of patients using Troxerutin for symptoms of hemorrhoids are usually positive. The medicine today is produced under different names and can be sold in the form of a gel, capsules and even injections.

Gel

The 2% gel should not be applied to open wounds, including bleeding hemorrhoids. It is rubbed into the skin next to the painful areas.

  • The amount of gel depends on the area of ​​damage, but it is recommended to apply it in a small layer. In case of contact with eyes, rinse immediately with clean water.
  • It is advisable to avoid exposure to treated areas of the skin of ultraviolet radiation. One gram of gel contains 20 milligrams of Troxerutin.

Capsules

A common form of release of the drug is capsules that contain 300 milligrams of the active substance. During treatment, take 1-3 capsules per day for several weeks.

The duration of treatment can be extended up to a month or more. With maintenance therapy, patients are prescribed the minimum dosage: one capsule per day. Use is allowed only on the recommendation of a doctor.

Capsules should be taken before meals with plenty of water.

Solution in ampoules (10%)

In some cases, patients are prescribed intramuscular or intravenous injections of the solution. The standard term for such treatment is 10 days (injected every other day), after which the patient is usually transferred to capsules.

Therapeutic and medicinal properties

Reviews of experts also allow us to characterize the drug as highly effective in the treatment of hemorrhoids. This has been proven by numerous clinical studies.

So, scientists from the State Scientific Center of Coloproctology concluded that the most effective remedy can be used to treat thrombosis of external nodes.

However, it will be very useful for those who suffer from chronic hemorrhoids, both internal and external.

According to numerous patient reviews, the most effective way to treat hemorrhoids with Troxerutin is to use capsules and gel at the same time. If necessary, appoint a daily intake of two or three capsules (preferably taken before meals). The gel is carefully but gently rubbed around the anus in small portions twice a day, it is better to do this in the morning and evening, before going to bed.

According to studies, after a ten-day course of treatment, the pain of hemorrhoids is significantly reduced, the size of the perianal hematoma decreases, and bleeding from the anus ceases to bother. At the same time, there is evidence that Troxerutin is practically useless in acute hemorrhoids: it does not help to cope with itching and burning in the anus.

The average cost of a gel in Russia is 58 rubles. A pack of capsules (50 pieces) can be bought for 280-290 rubles.

Troxevasin

One of the well-known analogues of Troxerutin is Troxevasin, which is often used in the fight against bruises and "bags" under the eyes. In principle, these drugs are identical. One capsule contains 300 milligrams, and one gram of gel contains 20 milligrams of Troxerutin. Apply the drug according to the same scheme. They have the same contraindications and, according to patient reviews, some side effects.

Some doctors believe that it is more appropriate to use drugs based on diosmin instead of Troxerutin. However, the medicine still has adherents, since the drug has existed for a long time and has helped many in the fight against hemorrhoids.

How to treat hemorrhoids at home

Have you ever tried to get rid of hemorrhoids at home on your own? Judging by the fact that you are reading this article, the victory was not on your side. And of course you know firsthand what it is:

  • once again see blood on paper;
  • wake up in the morning with the thought of how to reduce swollen painful bumps;
  • suffer every trip to the toilet from discomfort, itching or an unpleasant burning sensation;
  • again and again to hope for success, to look forward to the results and be upset by the new ineffective drug.

Now answer the question: does it suit you? Is it possible to put up with this? And how much money have you already “leaked” on ineffective drugs? That's right - it's time to end them! Do you agree? That is why we bring to your attention the method of Marta Volkova, who told about an effective and inexpensive way to get rid of HEMORRHOIDS forever in just 5 days ... Read the article>>>

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Reviews about the drug Troxerutin gel

On pharmacy shelves you can find a wide variety of products that promise to relieve the symptoms of varicose veins, swelling and inflammation. Numerous positive reviews about the drug Troxerutin gel indicate that it has a good therapeutic effect and is able to get rid of the problem.

Troxerutin gel: instruction

With such an unpleasant disease as varicose veins, a huge number of people face. It's all to blame - a sedentary lifestyle and heredity. To combat the disease, complex therapy is needed, which must include topical preparations.

Angioprotector, bioflavonoid Troxerutin gel with the active ingredient of the same name is able to reduce capillary permeability and seal the walls of blood vessels. The drug blocks the venodilatory action of bradykinin and histamine (inflammatory mediators). Stabilizes hyaluronic acid in cell membranes, counteracting hyaluronidase.

The drug is prescribed to patients with the following indications:

  • Superficial thrombophlebitis
  • Hematomas
  • Varicose disease
  • Swelling after soft tissue injury
  • Venous insufficiency
  • Phlebothrombosis
  • Ankle swelling
  • Inflammation of hemorrhoids
  • Sprain, muscle injury
  • Ligament injury
  • Varicose dermatitis
  • Bechterew's disease
  • Osteochondrosis, sciatica

To achieve a positive therapeutic effect, it is necessary to use Troxerutin gel daily. A small amount is applied to the sore spot and rubbed with smooth movements.

This procedure should be repeated up to 4 times a day. Depending on the severity of the pathology, the therapeutic course varies from 10 days to 1 month. In some cases, it is allowed to use the gel and Troxerutin capsules at the same time.

It is necessary to refrain from using the product if there is a predisposition to an allergic reaction to the active substance or auxiliary components. Also, a contraindication will be age up to 15 years and the presence of renal failure.

Troxerutin gel is able to cope with "heavy legs syndrome", hematomas and edema.

Troxerutin gel: reviews

An angioprotective agent in the form of a gel has proved indispensable for many people with venous insufficiency and varicose veins. According to reviews, the drug quickly copes with pain, heaviness in the legs. In rare cases, an allergy in the form of a rash and itching associated with an overdose may occur.

See also: Treatment of a burst vessel in the eye, how to remove swelling

The agent can be applied to hematomas formed at the injection sites. Bruises resolve within a few days, if you do not forget to use the gel at least twice a day.

A significant advantage is the low cost of Troxerutin, while not affecting the quality and therapeutic effect compared to expensive imported analogues. This is confirmed by the majority of patients who are forced to regularly seek help from such medications. The complete absence of the effect of treatment with the drug is rare.

In addition to the treatment of varicose veins, swelling and bruises, Troxerutin gel is successfully used for hemorrhoids. Almost all pregnant women experience symptoms of this unpleasant disease.

In this position, it is important not only to eliminate pain and discomfort, but also not to harm the developing fetus. The gel is a safe medicine, and it is allowed to use it while carrying a baby.

The active substance blocks the negative, destructive effect of hyaluronidase, an enzyme that destroys hyaluronic acid polymers. In addition, the drug reduces the visibility of the couperose (vascular) network on the face. As a cosmetic, it is applied to clean, damp skin, preferably at night.

Laudatory reviews Troxerutin gel will deserve not only in the treatment of varicose veins, but also as a cosmetic product to maintain the elasticity of the skin of the face.

Troxerutin gel: analogues

Angioprotectors are in great demand and therefore in the pharmacy you can find a substitute for Troxerutin gel with a similar active ingredient. The drugs differ in pricing policy (sometimes even 3-4 times), but the therapeutic effect is almost always exactly the same.

Troxevasin

The most famous and expensive analogue is Troxevasin. The gel has an identical amount of the active ingredient troxerutin. Comparing the instructions of Troxevasin and Troxerutin, it is not easy to find differences.

It is prescribed if necessary to relieve swelling, restore venous circulation, affect inflammatory processes in hemorrhoids, bruises, sprains. The drug is produced in Bulgaria. The difference in price is due to the fact that Troxevasin belongs to the original drugs that have passed clinical trials.

Troxegel

Another good analogue is Troxegel. This is a fairly strong angioprotector that can improve the tone of the veins, strengthen the vascular walls and protect the capillaries. Effectively treats varicose veins, thrombophlebitis, muscle spasms.

Removes puffiness and feeling of heaviness. According to the instructions, it can be used to treat various injuries and bruises in children. The gel is also safe for expectant mothers. Troxegel is an inexpensive analogue of Troxerutin.

Venoruton

Venoruton has a phlebotonizing, angioprotective effect due to the active ingredient - troxerutin. The drug is produced in the form of a gel for topical application and capsules. Indications for use are symptoms of venous insufficiency, trophic ulcers, pain syndrome with hemorrhoids (including in pregnant women), swelling, bruises.

The remedy can reduce blood stasis by reducing its flow to the skin. In terms of pricing policy, it practically does not differ from Troxevasin.

Troxerutin gel has many analogues in different price groups.

Thrombophlebitis: treatment and prevention

A disease such as thrombophlebitis can significantly spoil the appearance of the legs. It develops most often against the background of varicose veins, and in severe forms it can lead to gangrene, heart failure, and pulmonary embolism. The danger lies in the fact that a detached blood clot almost instantly leads to death.

You need to start the treatment of a serious illness with a visit to a phlebologist. An examination is scheduled to identify the cause of the pathology.

Depending on the depth of damage to the veins, the method of medical treatment will be determined.

The patient is shown intravenous administration of drugs that promote the resorption of detected blood clots and prevent the process of their formation. Local remedies are also used.

The best prevention of thrombophlebitis is the timely treatment of varicose veins. At the first signs, it is necessary to start therapy, having previously visited a specialist. Sports activities, warm-up, exercises are also welcome.

To prevent stagnation in the veins, it is necessary to raise the legs during the rest period. During long journeys, when you have to sit for a long time, it is recommended to change the position of the body as much as possible, move your fingers and feet, drink more liquid.

If at work a person needs to spend most of his time standing, you need to choose the right shoes, try to do a light warm-up, and rest your legs in a horizontal position during breaks.

Learn more about venous insufficiency in this video.

Troxerutin gel is an affordable remedy for influencing venous and vascular pathologies. Despite the safety and positive reviews, it is better to use it after consulting a specialist.

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Instructions for use

The drug Troxerutin belongs to the group of venotonic agents for external use.

Release form and composition of the drug

The drug Troxerutin is available in the form of a gel for external use. The gel is packed in aluminum tubes with a volume of 25 g, a detailed annotation with a description is included in the pack with the preparation.

The gel is odorless and colorless, 100 g of the drug contains 2 g of the active active substance Troxerutin, disodium edetate, benzalkonium sodium chloride hydroxide solution, purified water act as auxiliary components.

Indications for use

Troxerutin gel is intended for topical use for the treatment and prevention of the following conditions:

  • phlebeurysm;
  • swelling of the legs, pain and a feeling of heaviness in the calf muscles caused by chronic venous insufficiency;
  • varicose dermatitis;
  • thrombophlebitis.

The drug is highly effective for preventing and reducing hematoma, which occurs as a result of a bruise, injury, sprain.

Contraindications

The drug has some contraindications, so before applying the gel to the skin, carefully read the attached annotation. Troxerutin should not be applied to the skin in the presence of the following conditions:

  • age up to 14 years;
  • violation of the integrity of the skin at the site of application - scratches, bleeding wounds, weeping eczema;
  • individual intolerance to the drug.

A relative contraindication is renal failure, since the substances of the gel, although in small quantities, are still absorbed into the general bloodstream.

Method of application and dosage

Troxerutin gel is for external use only. The drug is applied to the affected area of ​​​​the body with a thin layer and lightly rubbed until absorbed with massaging movements.

If necessary, the drug can be applied under an occlusive dressing. The gel is applied twice a day - in the morning and at bedtime, the duration of the course of treatment is determined by the doctor, depending on the severity of varicose veins.

According to the instructions, the gel is used for 5-10 days.

Use of the drug during pregnancy and breastfeeding

Troxerutin gel is not prescribed to treat vein problems in the first trimester of pregnancy. This is due to the fact that clinical experience with the use of the drug at this stage of pregnancy is limited or absent, and safety for the fetus has not been established.

The use of the drug in this dosage form in the second and third trimesters is possible under the supervision of a physician in the event that the expected therapeutic effect for the mother is higher than the possible risks for the unborn child.

Troxerutin Vetprom is produced by the Bulgarian pharmaceutical company Vetprom A.D. Presented as a light transparent gel, it is very effective for various symptoms of chronic venous insufficiency, varicose dermatitis, superficial thrombophlebitis and periphlebitis, muscle spasms and other vein problems. Typically, the duration of treatment with this drug is from two to eight weeks.

After that, two or three times a year, repeated courses are held. It is easy and convenient to use Troxerutin Vetprom gel - apply a thin layer on the affected areas twice a day.

He has practically no contraindications, with the exception of a very high degree of sensitivity to the main and / or auxiliary components, the first trimester of pregnancy, as well as a violation of the integrity of the skin. In order for the treatment to be as effective and favorable as possible, before starting it, you should carefully read the instructions.

Release form and composition

The drug Troxerutin Vetprom is presented in the form of a gel for external use. It has a uniform, light and transparent texture, and can be yellow or yellow-green in color. Produced in aluminum tubes of 40 g, additionally packed in a cardboard box.

The active ingredient in its composition is the substance of the same name troxerutin.

Additionally added:

  • trolamine;
  • carbomer;
  • trisodium edetate;
  • benzalkonium chloride;
  • trolamine;
  • carbomer.

pharmachologic effect

Troxerutin, which is the active ingredient of this drug, has a pronounced angioprotective and venotonic effect. Therefore, as a result of the use of Troxerutin Vetprom, favorable changes occur:

  • fragility and permeability of capillaries decreases;
  • the tone increases;
  • the walls of blood vessels are strengthened;
  • microcirculation is enhanced;
  • reduces the likelihood of edema;
  • the exudation of the liquid part of the plasma decreases;
  • the diapedesis of blood cells decreases;
  • redox processes occur;
  • hyaluronidase is blocked;
  • hyaluronic acid of cell membranes is stabilized;
  • the inflammatory process in the vascular wall is eliminated;
  • the adhesion of platelets to the surfaces of vessel walls is limited.

The active substance of the gel, when applied topically, quickly penetrates through the epidermis. Within half an hour, it gets further into the dermis, and then, after another two to five hours, into the subcutaneous fat.

Indications for use

Gel preparation Troxerutin Vetprom is prescribed for the following conditions:

  • phlebeurysm;
  • feeling of fatigue, swelling, convulsions and paresthesia in the lower extremities;
  • varicose dermatitis;
  • chronic venous insufficiency, accompanied by severe edema and pain;
  • soreness and feeling of heaviness in the legs;
  • ankle swelling;
  • acute superficial thrombophlebitis;
  • acute superficial rephlebitis;
  • swelling and pain, which are the result of injuries;
  • swelling after surgery;
  • soft tissue rheumatism.

In addition, the drug can be used in the complex therapy of hemorrhoids.

Mode of application

Gel Troxerutin Vetprom is applied twice a day - in the morning and evening. Between applications, you must observe an interval of at least 10-12 hours.

A thin layer of the drug should be applied with light movements to the affected area of ​​​​the skin until it is completely absorbed. To enhance the effect, you can additionally wear elastic stockings or bandages.

One course of treatment, depending on individual indications, can last from two to eight weeks. After its completion, you need to pause, and then repeat if necessary. In total, two or three such courses are allowed throughout the year.

When using Troxerutin Vetprom gel, it is important to ensure that it does not get into the eyes and mucous membranes.

Interaction with other drugs

There is no information on the adverse interaction of Troxerutin Vetprom gel with other drugs. To enhance the effect, it can be used in conjunction with ascorbic acid.

Side effects

As a rule, the gel preparation Troxerutin Vetprom is easily tolerated, however, local side effects are possible in some cases:

  • redness, itching and contact dermatitis;
  • skin rash, sensations of heat and burning at the site of application.

After the abolition of further use of the drug, these manifestations disappear.

Overdose

With too long-term use of Troxerutin Vetprom in large quantities, all of the listed side effects increase.

If the drug accidentally got inside the body, you should immediately rinse the mouth and stomach, and then carry out symptomatic therapy.

Contraindications

There are few contraindications for Troxerutin Vetprom:

  • hypersensitivity to active and / or auxiliary components;
  • the presence of open wounds and damage to the skin;
  • age under 15 years old.

During pregnancy

The first trimester of pregnancy and lactation are also contraindications to the use of Troxerutin Vetprom.

special instructions

Influence on the ability to drive vehicles and control mechanisms

Currently, there is no information about the effect of the drug during the management of complex mechanisms, driving vehicles and performing any other actions that require increased concentration and speed of reactions.

Pregnancy and lactation

During the first trimester of pregnancy, it is necessary to refrain from using the drug Troxerutin Vetprom, since its components negatively affect the development of the fetus. Also, you can not use this tool during breastfeeding.

Application in childhood

Children and adolescents under the age of 15 cannot use Troxerutin Vetprom.

For impaired renal function

People who have kidney failure should not use Troxerutin Vetprom for too long.

;
  • Askorutin;
  • To choose the most suitable among them, you should consult with a qualified doctor.

    In this article, you can read the instructions for using the drug Troxerutin. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Troxerutin in their practice are presented. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Troxerutin in the presence of existing structural analogues. Use for the treatment of varicose veins, hemorrhoids and bruises in adults, children, as well as during pregnancy and lactation. The composition of the drug.

    Troxerutin- venotonic, angioprotective agent, bioflavonoid. It reduces the permeability and fragility of capillaries, strengthens the vascular wall, improves microcirculation, and has a decongestant effect. Participates in redox processes, blocks hyaluronic acid of cell membranes. Increases the density of the vascular wall, reduces the exudation of the liquid part of the plasma and diapedesis of blood cells. Reduces inflammation in the vascular wall by limiting the adhesion of platelets to its surface.

    Patients with chronic venous insufficiency are recommended to use both in the initial and late stages of the disease. In conditions characterized by increased vascular permeability (including scarlet fever, influenza, measles, allergic reactions), it is used in combination with ascorbic acid to enhance its effect.

    Non-toxic, has a wide range of therapeutic effects.

    Compound

    Troxerutin + excipients.

    Pharmacokinetics

    When the gel is applied to the skin, the active component of the gel quickly penetrates the epidermis, after 30 minutes it is found in the dermis, and after 2-5 hours in the s / c fatty tissue.

    After oral administration, the drug is absorbed from the gastrointestinal tract, the therapeutic plasma level is maintained for 8 hours.

    Metabolized in the liver, partially excreted unchanged in the urine and bile.

    Indications

    • chronic venous insufficiency;
    • trophic disorders in chronic venous insufficiency (dermatitis, trophic ulcers);
    • phlebeurysm;
    • superficial thrombophlebitis, periphlebitis;
    • post-thrombotic syndrome;
    • post-traumatic edema, hematomas;
    • haemorrhoids;
    • diabetic angiopathy, retinopathy.

    Release forms

    Gel for external use 2% (sometimes erroneously called ointment) Vramed and VetProm.

    Capsules 300 mg (sometimes erroneously called tablets) Zentiva and Vramed.

    Instructions for use and method of use

    Gel

    Outwardly: the gel is applied evenly in a thin layer in the morning and evening on the skin over the painful area and lightly massaged until completely absorbed. The dose of the drug depends on the area of ​​the damaged surface, but should not exceed 3-4 cm of gel (1.5-2 g). The gel can be applied under an occlusive dressing.

    Capsules

    The capsules should be swallowed whole with meals. Usually prescribed 1 capsule orally 3 times a day, as maintenance therapy - 1 capsule 2 times a day. The course of treatment averages 3-4 weeks, the need for longer treatment is determined individually.

    Side effect

    • headache;
    • irritation of the gastrointestinal mucosa;
    • allergic reactions in the form of skin rashes and itching.

    Contraindications

    • peptic ulcer of the stomach and duodenum, chronic gastritis (in the acute phase);
    • children's age up to 15 years;
    • hypersensitivity to the drug.

    Use during pregnancy and lactation

    Taking the drug Troxerutin is contraindicated in the 1st trimester of pregnancy. The drug can be used in the 2nd and 3rd trimester of pregnancy, as well as during lactation. The possibility of using the drug during pregnancy is determined by the doctor.

    Use in children

    There is no experience of using the drug in children under the age of 15 years.

    special instructions

    The drug should be used with caution (long-term use) in case of renal insufficiency.

    In the treatment of superficial thrombophlebitis or deep vein thrombosis, the use of Troxerutin does not exclude the need to prescribe anti-inflammatory and antithrombotic therapy.

    Influence on the ability to drive vehicles and control mechanisms

    Taking the drug Troxerutin Zentiva does not affect motor and mental reactions, does not interfere with driving and working with mechanisms.

    drug interaction

    With simultaneous use enhances the effect of ascorbic acid on the structure and permeability of the vascular wall.

    There are no data on the adverse interaction of troxerutin in the form of a gel with other drugs.

    Analogues of the drug Troxerutin

    Structural analogues for the active substance:

    • Troxevasin;
    • Troxevenol;
    • Troxerutin VetProm;
    • Troxerutin Vramed;
    • Troxerutin Zentiva;
    • Troxerutin Lechiva;
    • Troxerutin MIC.

    Analogues for the pharmacological group (drugs for the treatment of varicose veins):

    • Agapurin;
    • Agapurin retard;
    • Anavenol;
    • AngioNorm;
    • Antistax;
    • Antistax Gel;
    • Vasoket;
    • Vasonite;
    • Venin;
    • Venolife;
    • Venoplant;
    • Venoruton;
    • Viatromb;
    • Heparoid Lechiva;
    • Hepatrombin;
    • Ellon gel;
    • Indovazin;
    • Lyoton 1000;
    • Pentoxifylline;
    • Ralofect;
    • Reparil Gel H;
    • Rutin;
    • Stylamine;
    • Stugeron;
    • Thrombovar;
    • Ultralan;
    • Fibro Wayne;
    • Phlebodia 600;
    • Cyclo 3;
    • Cinnasan;
    • Emeran;
    • Aescusan;
    • Aesculus compositum.

    In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.