Piracetam maximum single dose. Why is Piracetam prescribed and what to expect from the medicine in different cases? Instructions for use, dosage for children and adults



Piracetam is the most important representative of the group of synthetic nootropic drugs. In terms of its chemical composition, it is a derivative of pyrrolidone and belongs to the “racetam” family. In Russia, the drug is widely used in psychiatric, drug addiction and neurological practice. Piracetam has a positive effect on cerebral circulation and improves metabolic processes in the brain.

Its use has a beneficial effect on learning ability by improving concentration and memory. In addition, the drug protects and restores brain functions affected by hypoxia (oxygen starvation) and intoxication.

Piracetam is an effective and practically harmless drug. For ease of use, it is produced in various dosage forms and is used to treat patients of different age groups. Let's take a closer look at what Piracetam helps with, in what cases it is prescribed and how to use it correctly.

Piracetam is a nootropic drug that has a positive effect on metabolism and cerebral circulation. The active substance - piracetam, acting directly on the brain, accelerates metabolic processes, improves blood microcirculation in ischemic areas, and promotes glucose utilization. Protects the brain from damaging factors (hypoxia, electric shock, toxins) and significantly improves its activity, helping to increase concentration, which facilitates the learning process.

The drug does not have a vasodilating effect, does not cause a sedative or psychostimulating effect. By improving connections between the hemispheres of the brain, Piracetam restores and normalizes consciousness, speech, memory, improves cerebral blood flow and increases mental performance.

When taken orally, it is completely absorbed from the gastrointestinal tract, quickly distributed in all tissues and organs, selectively accumulating in the cerebral cortex. The maximum concentration of the active substance in plasma is observed 30 minutes after taking the drug, in brain tissue - within 1-4 hours. It is excreted from the body unchanged by the kidneys.


Release form of the drug, composition

Photo: Release form of the drug Piracetam

Piracetam is available in several forms:

  1. Piracetam capsules(400 mg)
  2. Piracetam tablets(200 mg and 400 mg)
  3. Piracetam in ampoules(solution for injection 20%)

One capsule contains 400 mg of piracetam + excipients. 10 capsules are placed in blister packs and packed in cardboard packs, each of which contains 6 blister packs.

Piracetam tablets, film-coated, consist of 200 mg or 400 mg of active ingredient + excipients. Cardboard packages with the drug contain 60 tablets.


Piracetam solution is available in ampoules of 5 ml. 1 ml of solution contains 200 mg of active substance. The cardboard pack with the drug contains a blister pack containing 10 ampoules of solution.

Analogs

Piracetam has quite a few structural analogues containing the same active substance. We list the most popular of them:

  • Nootropil
  • Piracetam Richter
  • Memotropil
  • Lutsetam
  • Stamin
  • Cerebril

In the pharmacy chain, this inexpensive drug is dispensed with a doctor’s prescription. Average prices for Piracetam are:

  • Capsules (400 mg) – from 26 rubles
  • Tablets (200 mg) – from 38 rubles
  • Solution 20% (10 ampoules of 5 ml) - from 45 rubles

Indications for use

Piracetam has a wide range of applications; this medication is prescribed for the treatment of disorders in neurology, pediatrics, psychiatry and addiction. Let's take a closer look at why Piracetam is prescribed for various pathologies.

In neurological practice, Piracetam is used for the following conditions:


  • Diseases of the brain of a vascular nature (hypertension, atherosclerotic changes), which are complicated by the phenomena of chronic vascular insufficiency (memory impairment, distracted attention, speech difficulties, dizziness, impaired coordination of movements, migraines)
  • Acute and chronic circulatory disorders in the brain
  • Comatose states resulting from intoxication or brain injury
  • Disturbances in the functioning of the nervous system, accompanied by emotional disturbances and decreased intellectual abilities
  • Therapy for patients with Alzheimer's disease

In psychiatry, the drug is used for various pathological mental conditions:

  • Depression of various origins with a predominance of hypochondriacal and asthenic disorders, accompanied by symptoms of lethargy
  • Epilepsy
  • Prevention of mental, autonomic and neurological complications associated with poor tolerability of psychotropic drugs and antipsychotics
  • Apathetic states in schizophrenia
  • Complex therapy of mental disorders and depressive conditions

In narcology, Piracetam is prescribed as part of complex treatment:

  • For chronic alcoholism, which is accompanied by persistent mental disorders
  • When relieving alcohol withdrawal and alcoholic delirium
  • In case of acute poisoning with alcohol, drugs

In pediatrics, the drug is used for the following conditions:

  • Mental retardation
  • Cerebral palsy (cerebral palsy)
  • Mental retardation
  • Difficulties in the learning process
  • Dyslexia (impaired ability to read and write) in combination with other methods
  • Perinatal brain damage
  • As part of the combination treatment of sickle cell anemia

Piracetam is used as part of complex treatment for Parkinson's disease, severe depression, schizophrenia, neuroses and other mental disorders. The medicine has confirmed its effectiveness in the treatment of alcohol and drug poisoning; it is used to relieve attacks of delirium tremens and to restore brain activity in people suffering from chronic alcoholism.

Piracetam should be prescribed by a specialist. The doctor will individually select the required dose and treatment regimen, taking into account the severity of the symptoms, the general condition of the patient and possible contraindications. To avoid complications, you should not self-medicate and take the drug without medical advice.

Instructions for use

It is recommended to take the drug in capsule or tablet form before meals. In this case, the daily dose should be divided into 2-4 doses, this will help to avoid sleep disturbances. The final dose of medication should be taken no later than 17:00.


For acute conditions, the initial single dose is 800 mg, which must be taken three times a day. If the effect is positive, the dose can be reduced to 400 mg. The maximum daily dose is calculated based on body weight: for children – 30-50 mg/kg; for adults – 30 -160 mg/kg. The received doses are taken 2 to 3 times a day. The duration of treatment depends on the specific situation and can be from 2 to 8 weeks. If there is a need, then after a break the course of treatment is continued.

Piracetam for injections intramuscularly or intravenously is prescribed at an initial dose of 10 grams per day. For patients in serious condition, this dose can be increased to 12 grams. As soon as improvements in the condition begin to appear, the dose is reduced and switched to tablet forms.

In elderly patients with long-term therapy of psychoorganic disorders, the daily dose of Piracetam can vary between 1.2 - 2.4 grams; at the beginning of therapy, this dose can be doubled. In this case, the drug can be prescribed as part of a complex treatment simultaneously with taking other medications (psychotropic and cardiovascular drugs).

When treating comatose and post-traumatic conditions, the initial dose taken per day is from 9 to 12 g, the maintenance dose during treatment is 2.4 g per day. Duration of therapy is 3 weeks.

When treating alcoholism, 12 g of Piracetam is taken per day to relieve withdrawal symptoms. As for the maintenance daily dose, it is 2.4 grams.

For sickle anemia, the daily dose is calculated in the ratio of 160 mg/kg body weight and taken in 4 divided doses. In the treatment of cortical myoclonus, the initial daily dose is 7.2 grams, then it is increased every three days by 4.8 g until the maximum daily dose reaches 24 grams. After this, the dose is gradually reduced every two days by 1.2 g.

When treating dizziness and related balance disorders, the daily dose of 4.8 g is divided into 2-3 doses.

Intravenous injections are carried out by drip or jet. When administered by stream, the drug must be infused very slowly over 4-6 minutes. For sickle cell vaso-occlusive crisis in adults and children, the daily dose is determined at the rate of 300 mg/kg body weight and is administered intravenously in 4 doses. For complex treatment of dyslexia in children over eight years of age, the daily dose of 3.2 g is divided into two doses.

Piracetam for children

In pediatric practice, Piracetam is used to treat children with various mental development disorders and to eliminate disorders associated with brain damage in the perinatal period. Brain damage in a child can develop as a result of birth injuries, hereditary disorders, injuries during the newborn period, or as a result of infectious diseases suffered in early childhood.

Such disorders of brain activity manifest themselves in the inability to learn, long-term concentration and assimilation of information. Young patients are lagging behind in mental development, have difficulty speaking and expressing their thoughts, and have difficulty reading and writing. The use of Piracetam allows such children to become more active and helps achieve better assimilation and memory of information.

But doctors note that when treating children with mental retardation, the drug is not effective enough, while in children with normal intelligence but reduced brain function, Piracetam shows excellent results. After the course of treatment, it was noted that the children began to perceive and assimilate information better, were able to concentrate and complete the task faster, and became less tired.

At the same time, long-term use of Piracetam can provoke the development of side effects in children, manifested in increased nervousness and hyperactivity. Therefore, an individual approach to each small patient, an accurate calculation of the required dose and duration of treatment is very important. This can only be done by a specialist, and throughout the course of therapy the child must be under the supervision of a doctor.

Piracetam during pregnancy

Piracetam should not be prescribed during pregnancy and breastfeeding, since the active substance of the drug easily penetrates the placental barrier and can negatively affect the development of the fetus.

During lactation, the active substance is excreted in mother's milk, therefore, if treatment with Piracetam is necessary, breastfeeding is stopped for a while, and the child is transferred to artificial formula.

Contraindications

Piracetam should not be prescribed for the following conditions:

  • Hypersensitivity and intolerance to the components of the drug
  • Pregnancy and lactation
  • Children's age (up to 12 months)
  • Acute stage of hemorrhagic stroke
  • Severe renal failure
  • Huntington's chorea
  • Depression accompanied by psychomotor agitation

The drug should be prescribed with extreme caution in case of severe bleeding, extensive surgical interventions, or severe hemostasis disorders.

Side effects

Photo: Adverse reactions to the use of Piracetam

Adverse reactions to the use of Piracetam are most often observed in cases where the dose of the drug exceeds 5 g per day.

  • From the gastrointestinal tract, nausea, vomiting, abdominal pain, diarrhea or constipation are noted.
  • From the central nervous system, disorders such as headache, dizziness, poor coordination of movements, drowsiness or insomnia are observed. Taking the drug can aggravate the course of epilepsy, provoke symptoms of asthenia, depression, cause mental disorders, irritability, aggression, confusion, and hallucinations.
  • In some cases, the use of the drug causes allergic reactions (skin itching, rashes, swelling, symptoms of urticaria or dermatitis). In severe cases, angioedema and anaphylactic reactions are possible.

In addition to the above symptoms, the body may respond to taking Piracetam with fever, increased body weight, and decreased blood pressure. If adverse reactions occur, treatment with the drug should be stopped and consult a doctor to adjust the course of treatment.

Drug interactions

Piracetam, when taken simultaneously with antipsychotics, enhances their effect, which can cause tremors and unjustified anxiety in the patient.

When taken together with iodine-containing thyroid hormones, the patient may experience sleep disturbance, confusion and irritability.

special instructions
  1. In the treatment of acute circulatory disorders, the drug is prescribed as part of complex restorative and detoxification therapy; in the treatment of mental disorders, Piracetam is used in conjunction with psychotropic drugs.
  2. When treating cortical myoclonus, abrupt discontinuation of the drug should be avoided, otherwise the risk of recurrence of attacks increases significantly.
  3. If sleep disorders (insomnia) occur, you should stop taking the drug in the evening and combine this dose with the daytime dose.
  4. When treating patients with impaired liver and kidney function, monitoring the patient's condition is necessary.
  5. During Piracetam therapy, care should be taken when driving vehicles and performing hazardous work associated with increased concentration and speed of reactions.

Reviews about the use of Piracetam

Review #1

I had heard about nootropic drugs before, but somehow I had never tried them on myself. However, three months ago I still had to resort to the help of such medications. The reasons for this decision were constant fatigue, absent-mindedness and even dizziness. It was very difficult to focus my attention on anything important.

A friend suggested that perhaps my brain needed help. I didn’t go to the doctor, but decided to buy Piracetam. He was also recommended by the same friend. I went to the pharmacy and bought the drug in tablets. There were 60 tablets in one package. After studying the instructions, I realized that this would be enough for me for one course of treatment.

I started taking 2 tablets a day. The entire course lasted me a month. After about a week I noticed improvements: my head became clearer, my work became easier. There were no longer any noticeable problems with concentration. After a month of taking it, I completely felt like a fully functional person. Among other advantages of Piracetam, one can note its low cost: a pack of tablets cost me only 60 rubles.

Regina, St. Petersburg

Review #2

My three-year-old daughter had speech delay. She had difficulty making sentences of two or three words. Doctors recommended various remedies, but they were all too expensive. Then they advised Piracetam. I was pleasantly surprised by the price: 40 rubles per pack of tablets. I gave my daughter one tablet twice a day for two months.

At the same time as taking the drug, they intensively engaged in reading and retelling what they had read. A month after the start of such therapy, my daughter began to express herself much more expressively, and her vocabulary expanded. I was also pleased with the fact that no side effects were found when taking Piracetam. Maybe sleep disturbance a couple of times. But you can get rid of this: you just need to take the drug during the day.

Victoria, Moscow

Review #3

I have a very busy life: I study at the university, take English courses, and do fine arts. But when the session starts, I don’t have time to do anything. Nervousness, headaches and terrible fatigue appear.

It can be difficult to concentrate, and before exams you need to learn a lot of information. I recently discovered Piracetam. He became an assistant for me in such difficult periods.

The drug increases cerebral circulation, thereby improving memory and overall well-being. Now I drink it two weeks before the start of the session and successfully pass all exams. There are no side effects, and the drug itself is cheap.

Daria, Novosibirsk

In this article you can read the instructions for use of the drug Piracetam. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Piracetam in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Piracetam in the presence of existing structural analogues. Use for the treatment of vascular disorders, Alzheimer's disease, epilepsy and blood pressure in adults, children (including newborns), as well as during pregnancy and lactation. Action of the drug.

Piracetam- has a positive effect on metabolic processes in the brain, increases the concentration of ATP in brain tissue, enhances the biosynthesis of ribonucleic acid and phospholipids, stimulates glycolytic processes, and enhances glucose utilization. Improves the integrative activity of the brain, promotes memory consolidation, and facilitates the learning process. Changes the speed of propagation of excitation in the brain, improves microcirculation without having a vasodilating effect, and inhibits the aggregation of activated platelets. It has a protective effect against brain damage caused by hypoxia, intoxication, electric shock, enhances alpha and beta activity, reduces delta activity on the EEG, and reduces the severity of vestibular nystagmus.

Does not have a sedative or psychostimulating effect. The drug improves connections between the cerebral hemispheres and synaptic conduction in neocortical structures, restores and stabilizes cerebral functions, especially consciousness, memory and speech, increases mental performance, and improves cerebral blood flow.

Pharmacokinetics or effect of the drug

After oral administration, it is well absorbed and penetrates into various organs and tissues. Penetrates through the blood-brain and placental barriers, accumulates in brain tissue 1-4 hours after ingestion. It is eliminated from the cerebrospinal fluid much more slowly than from other tissues. Practically not metabolized. Excreted by the kidneys - 2/3 unchanged within 30 hours.

Indications

The drug is used in neurological, psychiatric and drug addiction practice.

Neurology:

  • vascular diseases of the brain (atherosclerosis, hypertension, vascular parkinsonism) with symptoms of chronic cerebrovascular insufficiency (impaired memory, attention, speech, dizziness, headache);
  • cerebrovascular accidents;
  • comatose states, consequences of injuries and intoxications of the brain in order to increase motor and mental activity;
  • diseases of the nervous system, accompanied by a decrease in intellectual-mnestic functions and disturbances in the emotional-volitional sphere;
  • symptomatic treatment in patients with Alzheimer's disease and senile dementia of the Alzheimer's type.

Psychiatry:

  • neurotic and astheno-dynamic depressive states of various origins with a predominance in the clinical picture of signs of adynamia, asthenic and senesto-hypochondriacal disorders, phenomena of ideational inhibition;
  • sluggish-apathetic defective states in schizophrenia, psychoorganic syndromes of various etiologies, senile and atrophic processes;
  • complex therapy of mental illnesses occurring on “organically defective soil”;
  • complex therapy of depressive conditions resistant to antidepressants;
  • poor tolerability of neuroleptics and other psychotropic drugs in order to eliminate or prevent the somatovegetative, neurological and mental complications they cause;
  • epilepsy.

Narcology:

  • relief of withdrawal, pre- and delirious states in alcoholism, drug addiction, in case of acute poisoning with alcohol, morphine, barbiturates, phenamine;
  • chronic alcoholism with symptoms of persistent mental disorders (asthenia, intellectual and mental disorders).

Pediatrics:

  • if necessary, speed up the learning process and eliminate the consequences of perinatal brain damage, mental retardation, mental retardation, and cerebral palsy.

In the complex therapy of sickle cell anemia.

Release forms

Capsules 400 mg.

Tablets 200 mg and 400 mg.

Solution for intravenous and intramuscular administration 200 mg/ml (injections) (in ampoules of 5 ml).

Instructions for use and dosage

Tablets or capsules

Orally at the beginning of treatment, 800 mg is prescribed in 3 divided doses before meals; as the condition improves, the single dose is gradually reduced to 400 mg. Daily dose - 30-160 mg/kg body weight, frequency of administration - 2 times a day, if necessary - 3-4 times a day. The course of treatment lasts from 2-3 weeks to 2-6 months. If necessary, the course of treatment is repeated.

For long-term therapy of psychoorganic syndrome in the elderly, the drug is prescribed at 1.2-2.4 g per day; loading dose during the first weeks of therapy is up to 4.8 g per day. Treatment with piracetam, if necessary, can be combined with the use of psychotropic, cardiovascular and other drugs.

When treating the consequences of comatose states, in the post-traumatic period, the initial dose is 9-12 g per day, maintenance dose is 2.4 g, the course of treatment is 3 weeks.

For alcoholism - 12 g per day during the period of manifestation of alcohol withdrawal syndrome; maintenance dose - 2.4 g.

For sickle cell anemia, the daily dose is 160 mg/kg body weight, divided into 4 equal portions.

Attention: take the last single dose no later than 17.00 to prevent sleep disturbances.

Injections

Intravenous stream or drip, intramuscular. The daily dose is divided into 2-4 doses.

Symptomatic treatment of psychoorganic syndrome: 4.8 g per day during the first week, then switch to a maintenance dose of 1.2-2.4 g per day.

Treatment of dizziness and related balance disorders: 2.4-4.8 g per day.

Treatment of cortical myoclonus: start with a dose of 7.2 g per day, every 3-4 days the dose is increased by 4.8 g per day until a maximum dose of 24 g per day is reached. Treatment is continued throughout the entire period of the disease. Every 6 months you should try to reduce the dose or discontinue the drug, gradually reducing the dose by 1.2 g per day every 2 days. If there is little or no therapeutic effect, treatment is stopped.

For sickle cell vaso-occlusive crisis (in adults and children): intravenously, 300 mg/kg per day, divided into 4 equal doses.

Treatment of dyslexia in children over 8 years of age (in combination with other treatment methods) - 3.2 g, divided into 2 equal doses.

Side effect

Side effects are most often observed at doses above 5 g per day:

  • nervousness;
  • excitation;
  • irritability;
  • anxiety;
  • sleep disorder;
  • nausea, vomiting;
  • diarrhea, constipation;
  • anorexia;
  • dizziness;
  • headache;
  • convulsions;
  • increased sexual activity;
  • weakness;
  • drowsiness;
  • fussiness;
  • anxiety;
  • restlessness;
  • motor disinhibition;
  • decreased ability to concentrate;
  • imbalance;
  • increased conflict.

Contraindications

  • renal failure (creatinine clearance less than 20 ml/min);
  • hemorrhagic stroke (acute stage);
  • depression with anxiety (aggressive depression);
  • Huntington's chorea;
  • pregnancy;
  • lactation;
  • children's age (up to 1 year);
  • hypersensitivity.

Use during pregnancy and breastfeeding

Adequate and strictly controlled studies of the safety of piracetam during pregnancy have not been conducted. Use is possible only in cases where the expected benefit to the mother outweighs the possible risk to the fetus.

Piracetam appears to pass into breast milk. If it is necessary to use it during lactation, the issue of stopping breastfeeding should be decided.

Experimental studies on animals did not reveal any negative effects of piracetam on the fetus.

special instructions

In the treatment of acute brain lesions, piracetam is prescribed in combination with other methods of detoxification and rehabilitation therapy, and in the treatment of psychotic conditions - with psychotropic drugs.

When treating patients with cortical myoclonus, abrupt discontinuation of the drug should be avoided (risk of resumption of attacks).

Prescribe with caution in patients with impaired hemostasis, after extensive surgery, severe bleeding.

Impact on the ability to drive vehicles and operate machinery

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Drug interactions

Increases the effectiveness of thyroid hormones, indirect anticoagulants (against the background of high doses of piracetam), psychostimulants.

When prescribed with antipsychotics, it reduces the risk of extrapyramidal disorders.

When taken simultaneously with antipsychotics, their central effect (tremor, anxiety, etc.) increases.

Analogues of the drug Piracetam

Structural analogues of the active substance:

  • Lutsetam;
  • Memotropil;
  • Nootobril;
  • Nootropil;
  • Noocetam;
  • Pirabene;
  • Pyramem;
  • Pyratropil;
  • Piracetam Bufus;
  • Piracetam MS;
  • Piracetam Obolenskoe;
  • Piracetam Vial;
  • Piracetam-ratiopharm;
  • Piracetam-Richter;
  • Piracetam-Eskom;
  • Stamin;
  • Cerebril;
  • Escotropile.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps and look at the available analogues for the therapeutic effect.

Piracetam is a synthetic nootropic drug widely used in psychiatric and neurological practice.

pharmachologic effect

The active substance of Piracetam, acting directly on the brain, improves cognitive processes such as memory, learning ability, attention and mental performance. In addition, the drug has a restorative and protective effect in cases of brain dysfunction caused by intoxication and hypoxia.

According to the instructions, Piracetam has different effects on the central nervous system:

  • Affects blood viscosity without having a vasodilating effect;
  • Improves metabolic processes of nerve cells;
  • Improves microcirculation;
  • Changes the speed of propagation of impulses in the brain.

When using Piracetam, the connection between the cerebral hemispheres, cerebral blood flow and synaptic conduction in neocortical structures improves.

Release form

Piracetam is available in dosage form:

  • Capsules, 400 mg each. 60 pieces per pack;
  • Film-coated tablets, 200 mg each. 60 pieces per pack;
  • 20% solution for injection, in ampoules of 5 ml.

Analogues of Piracetam by mechanism of action are the drugs Lucetam, Memotropil, Nootropil, Piracetam-AKOS, Escotropil.

Indications for use of Piracetam

Piracetam is prescribed to adults according to the instructions:

  • For the treatment of dizziness (vertigo), as well as related balance disorders, except for cases of dizziness of psychogenic and vasomotor origin;
  • For the symptomatic treatment of psychoorganic syndrome with an accompanying decrease in activity, memory and concentration, as well as changes in behavior, mood and gait;
  • For the prevention and relief of sickle cell vaso-occlusive crisis;
  • For the treatment of cortical myoclonus both in monotherapy and as part of complex therapy.

According to indications, Piracetam is prescribed to children in the following cases:

  • Dyslexia, usually in combination with other methods, including speech therapy;
  • Sickle cell vaso-occlusive crisis, for prevention and relief.

Contraindications

According to the instructions, Piracetam is contraindicated for use in:

  • Hypersensitivity to one of the components of the drug;
  • Hemorrhagic stroke;
  • Pregnancy and lactation;
  • Psychomotor agitation;
  • Chronic renal failure (creatinine clearance less than 20 ml/min);
  • Huntington's chorea.

In addition, according to indications, Piracetam should be used with caution in the following cases:

  • Chronic renal failure (creatinine clearance 20-80 ml/min);
  • Hemostasis disorders;
  • heavy bleeding;
  • Extensive surgical interventions.

How to use Piracetam

According to indications, Piracetam in capsule form is recommended to be taken on an empty stomach or with meals. The daily dose is most often divided into 2-4 doses, and the last dose should be taken no later than 17 hours so as not to cause sleep disturbances. Piracetam in the form of an injection solution can be used intravenously and intramuscularly in cases of unconsciousness or difficulty swallowing.

When using Piracetam for the treatment of cortical myoclonus, the initial dose of 7.2 g per day is increased by 4.8 g every three days. Throughout the entire period of the disease, treatment is carried out by taking 24 g of the drug per day. After six months of therapy, it is recommended to try to stop the drug or reduce the daily dose, gradually reducing it by 1.2 g per day. If the use of Piracetam produces little therapeutic effect, treatment should be discontinued. It is not recommended to abruptly discontinue the drug to avoid resumption of attacks.

For symptomatic treatment of psychoorganic syndrome, during the first week of therapy, take 4.8 g per day, after which the dose is reduced to a maintenance dose of 1.2-2.4 g.

When treating dizziness, as well as related balance disorders, 2.4-4.8 g of Piracetam per day is usually prescribed.

For the prevention of sickle cell vaso-occlusive crisis in children and adults, the daily dose of 160 mg per 1 kg of body weight is divided into 4 equal parts. During therapy, it should be taken into account that irregular use of Piracetam may cause an exacerbation of the disease. To treat the disease, the drug should be administered intravenously at 300 mg per 1 kg per day.

In children over 8 years of age, treatment of dyslexia with Piracetam, according to reviews, is effective in combination with other methods. In this case, you should take 4 capsules (400 mg) twice a day.

In case of chronic renal failure, it is necessary to adjust the dose taken depending on the severity of the disease:

  • For mild cases (creatinine clearance 50-79 ml/min), 2/3 of the recommended daily dose should be taken in 2-3 divided doses;
  • For moderate degrees (creatinine clearance 30-49 ml/min) – 1/3 of the daily dose, divided into 2 doses;
  • In severe cases (creatinine clearance 20-30 ml/min) – once 1/6 of the daily dose.

Side effects of Piracetam

Most often, when using Piracetam, according to reviews, disorders of the central nervous system are observed, such as:

  • Motor disinhibition;
  • Drowsiness;
  • Asthenia;
  • Insomnia;
  • Balance imbalance;
  • Hallucinations;
  • Irritability;
  • Depression;
  • Headache;
  • Exacerbation of the course of epilepsy;
  • Mental agitation;
  • Ataxia;
  • Anxiety;
  • Confusion.

In addition, in therapeutic doses, Piracetam, according to reviews, can cause:

  • Nausea, diarrhea, vomiting, abdominal pain;
  • Vertigo;
  • Anaphylactic reactions, hypersensitivity, angioedema;
  • Decreased blood pressure, fever;
  • Increased body weight;
  • Itching, dermatitis, urticaria;
  • Thrombophlebitis, pain at the injection site.

When using Piracetam in doses that exceed therapeutic doses, the risk of developing bloody diarrhea and abdominal pain increases. Since there is no specific antidote, in case of an overdose of Piracetam the following should be done:

  • Symptomatic therapy;
  • Induction of vomiting;
  • Gastric lavage;
  • Hemodialysis (effectiveness 50-60%).

When Piracetam is used simultaneously with iodine-containing thyroid hormones, irritability, confusion and sleep disturbance may occur.

Storage conditions

According to indications, Piracetam can be purchased with a doctor's prescription. The shelf life of ampoules with solution and capsules is 3 years, tablets – 24 months.

Today the entire civilized world is striving to improve the quality of its own life. People are trying to get an education, extend their creative period, and remain “sane” into old age. Unfortunately, the constantly accelerating pace of life, stress on the nervous system, and a not entirely favorable environmental situation hinder these aspirations. That is why the concept of “nootropics” is becoming more and more relevant.

Nootropics are substances created specifically to improve brain activity. They are used both by those suffering from certain diseases and by people seeking to improve the functions of their brain.

One of the most common drugs in the nootropic group is Piracetam. The use of this tool allows you to improve cognitive (cognitive) brain processes, stimulate intellectual abilities, and improve higher integrative brain activity.

Piracetam stabilizes brain function under heavy loads or adverse environmental influences.

Treatment and prevention of diseases associated with cerebral vascular pathology. These include atherosclerosis, Parkinson's disease, hypertension;

Improving memory, ability to concentrate, improving speech, attention;

Increased mental and physical activity after a state of coma, cerebral intoxication, brain injury;

Prevention and treatment of mental illnesses: asthenia, disorders of the emotional-volitional sphere, lethargy, depressive states of various origins;

In narcology: for detoxification, withdrawal symptoms, treatment of chronic drug addiction and alcoholism;

Treatment of headaches, dizziness.

This is not a complete list of diseases that can be cured with the help of the drug Piracetam. Its application is much wider. It not only speeds up the healing process, but helps improve memory and quickly absorb a large flow of information. That is why Piracetam is sometimes recommended to be taken by students and low-performing students during a session.

However, it should be remembered that no matter how positive the effect of the drug Piracetam is in most cases, its use without a doctor’s recommendation can be harmful.

The medicine is contraindicated in patients with renal and liver failure, and pregnant women.

The drug is produced in the form of tablets and liquid in ampoules for injection. What distinguishes these dosage forms from each other? Compound. "Piracetam" for injection consists only of piracetam itself, water, acetic acid and sodium nitrate. In addition to the active substance, the tablets contain povidone, starch, titanium and silicon dioxides, calcium, sugar, magnesium carbonate, and some other components.

How to take Piracetam? The course of treatment lasts at least 14 days. Doses are prescribed depending on the diagnosis and course of the disease. Typically, patients in a coma are administered intravenously or intramuscularly up to 12 g per day, the same amount during withdrawal, and for the treatment of stroke - up to 4.8 g per day. After half a month, they switch to a maintenance dose of 2 g. After this, the medicine can be taken orally (i.e., take Piracetam tablets).

Use of the drug in other cases may have a different dosage. The doctor determines the dose for each patient according to his indications. Tablets are usually taken for several months (up to six months), 2-4 times daily. You should not take more than 160 g per day. Piracetam tablets are prescribed to children. They are recommended to take the medicine three times a day, one tablet, for two weeks to two months.

The condition of a patient taking Piracetam should be constantly monitored by a doctor. If irritability, insomnia or drowsiness, agitation, or increased libido appear, you should immediately report this to a specialist.

Piracetam enhances the synthesis of dopamine in the brain, increases the content of norepinephrine. The drug also increases the amount of acetylcholine at the synaptic level and the density of cholinergic receptors. GABAergic elements cannot be excluded from the action of the drug, despite the fact that it does not convert into GABA. The drug has a positive effect on the processes of metabolism and blood circulation in the brain, stimulates redox processes, increases glucose utilization, improves regional blood flow in ischemic areas of the brain, and increases the body's energy potential with the participation of ATP and adenylate cyclase. Optimization of energy processes helps to increase the resistance of the central nervous system to hypoxia and various toxic factors. Piracetam improves integrative brain activity, promotes memory consolidation, improves learning processes.
Pharmacokinetics. When introduced into the body, it penetrates into various organs and tissues, including brain tissue. Practically not metabolized. Excreted by the kidneys. The half-life is about 4 hours; is excreted from the cerebrospinal fluid much more slowly, which indicates a high tropism of the drug for brain tissue.

Indications for use

The drug is prescribed for cerebral atherosclerosis, vascular parkinsonism, and other pathological processes with symptoms of chronic cerebrovascular insufficiency with impaired memory, attention, speech, dizziness, with changes in cerebral circulation, comatose and subcomatose states as a result of brain injuries and intoxications. Used for diseases of the nervous system with a decrease in intellectual-mnestic functions and disorders of the emotional-volitional sphere. In psychiatric practice, it is used for neurotic and asthenoadynamic depressive states with the advantage of signs of adynamia, asthenic, senesto-hypochondriacal disorders, ideational inhibition, for flaccid apathetic defective states, for schizophrenia, for psychoorganic syndromes of various etiologies, senile and atrophic processes, in the complex treatment of mental illnesses. Prescribed in the complex treatment of senile dementia, including Alzheimer's disease. In pediatrics, Piracetam is used for cerebrosthenic and encephalopathic disorders.
Piracetam used for emergency care in case of withdrawal, preliminary and delirious states of alcoholism, drug addiction, in case of acute poisoning with alcohol, morphine, barbiturates. In chronic alcoholism, Piracetam is prescribed to reduce the phenomena of asthenia, intellectual-mnestic and other mental disorders. The drug is advisable to use for viral neuroinfections to reduce cerebral ischemia and hypoxia. The antihypoxic effect of the drug should be taken into account in the complex therapy of myocardial infarction.

Mode of application

Inside, intravenously. Parenterally - intravenously, at an initial dose of 10 g; in severe conditions - intravenous drip, over 20-30 minutes - up to 12 g/day; after improvement, the dose is gradually reduced and switched to oral administration. Orally, at the beginning of treatment - 800 mg in 3 doses, before meals, as the condition improves, the single dose is gradually reduced to 400 mg; Duration of treatment - 6-8 weeks. Daily dose - 30-160 mg/kg, frequency of administration - 2 times a day, if necessary - 3-4 times a day. The duration of treatment ranges from 2-3 weeks to 2-6 months. If necessary, it can be repeated after 6-8 weeks. For long-term therapy of psychoorganic syndrome in the elderly - 1.2-2.4 g/day; loading dose during the first weeks of therapy is up to 4.8 g/day. When treating cerebrovascular disorders in the acute phase, it should be prescribed as early as possible, at a dose of 12 g/day for 2 weeks, and then 4.8-6 g/day. For cortical myoclonus, treatment begins with a dose of 7.2 g/day, every 3-4 days the dose is increased by 4.8 g/day until a maximum dose of 24 g/day is reached, 2-3 times a day, orally or parenterally. Every 6 months the dose should be reduced by 1.2 g every 2 days. When treating dizziness, the dose is 2.4-4.8 g/day in 2-3 doses. For sickle cell anemia, the daily dose is 160 mg/kg, divided into 4 equal portions. During a crisis - up to 300 mg/kg. For alcoholism - 12 g/day during the period of manifestation of ethanol “withdrawal” syndrome; maintenance dose - 2.4 g. In the treatment of comatose states, in the post-traumatic period, the initial dose is 9-12 g / day, maintenance - 2.4 g, course of treatment - 3 weeks. Children are prescribed a dose of 30-50 mg/day. Treatment should be long-term. Oral solution: daily dose - 3.3 g (8 ml of 20% solution or 5 ml of 33% solution) 2 times a day (before breakfast and dinner). Can be added to fruit juice or other drinks. For chronic renal failure with CC 50-79 ml/min, 2/3 of the usual dose is prescribed in 2-3 doses, with CC 30-49 ml/min - 1/3 of the dose in 2 doses, less than 30 ml/min - 1/6 of the usual dose , once.

Side effects

Mental agitation, motor disinhibition, irritability, imbalance, decreased ability to concentrate, anxiety, sleep disturbances, gastralgia, nausea, vomiting, constipation or diarrhea, decreased appetite, dizziness, headache, extrapyramidal disorders, convulsions, tremor, increased sexual activity, worsening of angina pectoris.

Side effects are most often observed at doses above 5 g per day.

Contraindications

Use of piracetam Contraindicated in acute renal failure in children with diabetes and a history of indications of allergic reactions associated with the consumption of fruit juices, essences, etc. The drug is not recommended for use in children under 1 year of age.

Interaction with other drugs

Increases the effectiveness of thyroid hormones, antipsychotic drugs (neuroleptics), indirect anticoagulants (against the background of high doses piracetam), psychostimulants. When prescribed with antipsychotics, it reduces the risk of extrapyramidal disorders.

Overdose

In case of an overdose, irritability, insomnia, and tremor occur; in elderly patients - exacerbation of heart failure. In this case, it is necessary to reduce the dose of the drug.

Release form

Capsules containing 0.4 g of piracetam in a package of 60 pieces; tablets of 0.2 g, film-coated (yellow), in packs of 60 or 120 pieces; 20% solution in ampoules of 5 ml (1 g of the drug in 1 ampoule) in a package of 10 pieces; Piracetam granules for children are light pink in color (brownish sediment is allowed), available in 56 g packages (2 g of piracetam, 50 g of sugar and fillers) in glass jars.

Storage conditions

List B. In a dry place, protected from light.

Synonyms

Nootropil, pyramems, apams, brains, cerebrohan, ceremonies, cyclocettes, zintilan, dinacel, dynagen, encephalux, e yourself, gabazet, gericites, mrapiran, noocephalum, pirates, pyrroxili, squeezers, euvifor, forteralural, non -statrophin, normbreine, but normabrein, but normabrein Rotrop, Norzetam, Stimubral.

Compound

Capsules contain 0.4 g of piracetam;
tablets of 0.2 g piracetam;
20% solution in ampoules of 5 ml - 1 g of the drug in 1 ampoule;
piracetam granules for children light - 2 g piracetam, 50 g sugar and fillers.

Additionally

You should constantly monitor indicators of renal function (especially in patients with chronic renal failure) - residual nitrogen and creatinine, and in patients with liver diseases - the functional state of the liver.
Abrupt withdrawal of the drug should be avoided. In patients receiving antiepileptic drugs during therapy with PIRACETam, the main therapy must be continued, since the seizure threshold may decrease.
In case of sleep disturbances, it is recommended to cancel the evening dose and add this dose to the daytime dose.
Penetrates through the filter membranes of hemodialysis machines.

Main settings

Name: PIRACETAM
ATX code: N06BX03 -

Piracetam is a synthetic nootropic drug - the first in the history of pharmacology and still the main remedy in this group.

The drug is used in psychiatry and neurology and has a wide range of applications. It began to be widely used only in 1972, although it was invented almost 10 years earlier.

First meeting

Piracetam improves blood circulation in the brain, which helps improve memory and eliminate neurological disorders.

It is prescribed to older people as a prophylactic against, to children to improve memory and behavior correction, to drug addicts and alcoholics to relieve withdrawal symptoms. This is a harmless remedy and is well tolerated by the patient. It should be taken only as prescribed by a doctor. The drug belongs to the pharmacological group - psychostimulants.

Piracetam has a beneficial effect on microcirculation and metabolic processes in the brain. Accelerates the utilization of glucose, stimulates metabolic processes in affected areas, and inhibits the activation of activated platelets. Shows protective properties against brain damage that occurs due to oxygen starvation, intoxication and electric shock.

Pharmacokinetics and composition of the drug

Piracetam is produced in the form:

  • capsules 0.4 g per pack of 60 pieces;
  • tablets, coated, 0.2 g each in a package of 120 pieces;
  • solution 20% for injections in ampoules of 5 ml, in a package - 10 ampoules.

The solution contains the active substance - piracetam, and auxiliary substances (sodium acetate, acetic acid and water). In addition to the active substance piracetam, tablets and capsules contain the following components:

  • stearate;
  • povidone;
  • ethylcellulose;
  • talc and other substances.

In appearance, these are oval white and rather large tablets and capsules with white powder inside in a gelatin shell.

The product is well absorbed and penetrates various tissues of the body. After taking the drug, its maximum concentration in plasma occurs within an hour. Penetrates through the blood-brain barrier, the placenta, and tends to accumulate in brain tissue and human organs.

It enters the brain tissue 1-4 hours after administration. It is most difficult to remove from the cerebrospinal fluid - this indicates a high tropism for brain tissue. While in the body, piracetam does not undergo biotransformation and is excreted unchanged from the body by the kidneys. Bioavailability is almost 100%, regardless of the form of the drug.

Mechanism of action

The mechanism of action of this drug is not fully understood. It increases the body's energy potential by accelerating ATP turnover, increasing adenylate cyclase activity and inhibiting nucleotide phosphatase.

Improvement in energy processes under the influence of piracetam leads to increased resistance of brain tissue during hypoxia and infection. Under the influence of the drug, the synthesis of nuclear RNA in the brain is enhanced.

Why is Piracetam prescribed by narcologists, neurologists and psychiatrists?

Piracetam is used in neurology, psychiatry and narcology; in neurological therapy it is used for the following indications:

In psychiatric practice, the medicine is used to treat the following diseases:

  • neurotic depression with signs of lethargy;
  • schizophrenia with a sluggish-apathetic effect, psychoorganic syndrome, atrophic process;
  • comprehensive treatment of mental illness;
  • comprehensive treatment of depression;
  • epileptic syndrome;
  • in case of poor tolerability of antipsychotics, to avoid complications.

Indications for the use of Piracetam in addiction treatment:

  • relief of withdrawal symptoms and for alcoholism, drug addiction and in case of acute poisoning with alcoholic beverages, barbiturates, morphine;
  • chronic alcoholism with permanent mental disorders.

In addition, the drug is used in pediatrics to improve the learning process, to eliminate the effects of brain damage during childbirth, mental retardation, and mental retardation.

Who will be harmed and even dangerous?

Piracetam should not be used to treat a patient if he has:

  • hypersensitivity to the components of the drug;
  • pregnancy and breastfeeding;
  • psychomotor agitation;
  • acute renal failure.

The drug should be taken with extreme caution if:

  • violation of hemostasis;
  • heavy bleeding;
  • extensive surgery;
  • chronic renal failure.

Piracity should not be prescribed to children under one year of age. The medication is prescribed by the attending physician according to indications and in accordance with the patient’s condition.

Dosages and course of treatment

The medicine is taken orally, in the form of intramuscular and intravenous injections.

Take the drug orally before meals.

Doses are prescribed by a doctor, but in accordance with the instructions, Piracetam is taken as follows.

Piracetam dosages for adult patients depending on the condition:

  1. Tablets and capsules for chronic diseases– 1200 mg per day, divided into 3 doses, gradually increase the dose to 3200 mg per day, and after improvement, reduce to 400 mg.
  2. Intramuscular injections– first 2-4 g per day, the next day – 4-6 g. The dose and course of treatment are prescribed by the doctor, based on the patient’s individual characteristics.
  3. Intravenously the drug is administered as a dropper, the daily dose is 4-12 g, the course of treatment is 2-4 weeks.

Children are given only the drug in tablets. For children aged 1 to 5 years – 800 mg per day, from 5 to 16 years – 1200-1600 mg.

Overdose cases? They are!

An overdose of the drug occurs with different amounts of the drug administered - it is impossible to establish the exact dosage. Do not take the medicine again or give an injection. In case of overdose, increased side effects are observed:

  • insomnia;
  • irritability.

Older patients may experience worsening heart failure. In this case, you need to reduce the dose of the medicine. In severe cases, gastric lavage and activated charcoal are taken.

Side effects are also not uncommon.

Side effects when taking Piracetam can be observed in several body systems.

Nervous system:

In addition, there may be manifestations from the gastrointestinal tract and other body systems:

  • nausea;
  • vomit;
  • diarrhea;
  • decrease in blood pressure;
  • fever;
  • weight gain;
  • hypersensitivity;
  • thrombophlebitis;
  • hives;
  • dermatitis;

special instructions

During treatment, it is necessary to regularly monitor the functioning of the liver and kidneys. Also, taking the drug can lead to insomnia, so evening medication should be taken no later than 17-18 hours.

Treatment of patients with cortical myoclonus does not allow abrupt withdrawal of Piracetam; attacks may recur.

Interaction with alcohol

Alcohol can increase or decrease the effect of Piracetam. You can take the drug after a 12-hour break after taking it alcohol.

If it is prescribed to relieve a hangover, then before taking it it is necessary to restore the water balance in the body, eliminate headaches with Aspirin or Citramon, remove toxins with activated charcoal, and only then relieve the hangover with the remedy in question.

The doctor chooses the dosage based on the patient’s weight and age.

Liver and kidney dysfunction

If the patient has impaired liver function, then adjustment of the dosage of the medication is not required. If kidney function is impaired, dosing is carried out depending on the QC indicator.

In late stage chronic renal failure, treatment with piracetam is contraindicated.

Interaction with other drugs

Simultaneous treatment with thyroid hormones leads to anxiety, irritability, tremors, sleep disturbances, and confusion.

When used with central nervous system stimulants, psychostimulant effects may be enhanced. Concomitant use with antipsychotics leads to increased.

Pregnancy, lactation and childhood

Piracetam is prescribed during pregnancy when the threat to the fetus is less than the risk to the mother.

The drug is not prescribed to pregnant women in any of the three trimesters, because it penetrates the placenta and accumulates in the baby’s brain, which can lead to a nervous breakdown in the baby.

The medicine is present in breast milk and is passed on to the baby, so it is necessary to either stop breastfeeding the baby or temporarily abandon the drug.

The drug is prescribed to children from one year of age. It is used to correct a student’s academic performance throughout the school year at a dose of 3.3 grams per day. Use the medicine for children only as prescribed by a doctor.

Theory without practice is blind...

A doctor's review of Piracetam and patient reviews will help to finally clarify the situation with the effectiveness and safety of the drug.

Doctor Review

Piracetam is one of the most popular medicines in our country for eliminating problems with the brain. It is distinguished by its availability and low cost, harmlessness and non-toxicity, and the possibility of taking it for preventive purposes.

The course of treatment should not exceed six months. Piracetam does not help as a stand-alone medicine for some diseases, so it is prescribed in combination with others. If the patient has headaches due to problems with the cervical spine, then the drug is powerless; the cause of the disease must be eliminated.

Udalova A. S., neurologist

Today we invite you to learn more about what the drug Piracetam is. This drug belongs to the group of nootropics and is widely used to combat mental and neurological diseases.

Description and effect of the drug

The drug "Piracetam", the indications for use of which extend to a number of diseases, is very popular today. This is due to the fact that its main component acts directly on the human brain, due to which cognitive processes are accelerated, learning ability is increased, attention, memory and mental work are normalized. In addition, this drug helps restore and protect brain functions during intoxication and hypoxia. The drug "Piracetam" also affects the central nervous system (CNS). At the same time, it helps to normalize the metabolism of nerve cells, accelerates the spread of impulses in the human brain, and also has an effect on microcirculation. Thus, interhemispheric connections, synaptic conduction and blood flow improve in the brain.

Existing dosage forms

Today, manufacturers offer various forms of the drug Piracetam. Indications for the use of each of them should be determined solely by your attending physician. So, the drug in question can be purchased in pharmacies in the following forms:

Capsules containing the active substance in the amount of 400 mg. Each package contains 60 capsules.

Film-coated tablets (200 mg of active ingredient). Each package contains 60 tablets.

20% solution for injection. Each ampoule contains 5 mg of the drug.

The drug "Piracetam": indications for use

The drug in question is used in psychiatric, neurological, as well as drug addiction and pediatric practice. We propose to dwell in more detail on each of these areas.

Neurology

The drug "Piracetam" is used for the treatment of vascular diseases of the brain (hypertension, atherosclerosis and others), accompanied by chronic cerebrovascular insufficiency (impaired attention, memory, speech, headaches, dizziness). In addition, this drug is effective in various cerebrovascular disorders, comatose states, diseases of the nervous system, accompanied by disturbances in the emotional-volitional sphere, as well as a decrease in intellectual and mnestic functions. In addition, the drug "Piracetam" is suitable for the symptomatic treatment of people suffering from Alzheimer's disease.

Psychiatry

This drug is widely used for neurotic and astheno-dynamic depressive states of various origins, as well as for sluggish-apathetic depressive states in the case of schizophrenia and psychoorganic syndromes of various etiologies. In addition, the drug "Piracetam" is suitable for the complex treatment of depressive conditions, when the patient is resistant to antidepressants, as well as intolerant to antipsychotics and other types of psychotropic drugs. This drug is also indicated for use in epilepsy.

Narcology

The drug "Piracetam", the indications for use of which also include the drug treatment sector, is used to combat withdrawal symptoms, as well as pre- and delirious states in drug addiction and alcoholism, in case of severe poisoning with alcohol, morphine, barbiturates or phenamine. In addition, the drug in question is recommended for use in chronic alcoholism, accompanied by persistent mental disorders.

Pediatrics

The drug "Piracetam" is indicated for use if it is necessary to accelerate the learning process and eliminate the consequences of perinatal brain damage. This medicine is also widely used for oligophrenia, Cerebral palsy (cerebral palsy) and mental retardation.

Contraindications

This drug is prohibited for use in the following cases:

In acute renal failure;

With agitated depression;

During pregnancy and breastfeeding;

If the patient has hypersensitivity to the components of the drug.

In addition, the drug "Piracetam" is contraindicated for use by children under 1 year of age.

Side effects

Like most existing medications, Piracetam can have a number of side effects on patients. Thus, often when using this drug, patients experience drowsiness, motor retardation, imbalance, asthenia, hallucinations, insomnia, irritability, depression, headaches, anxiety, mental agitation, ataxia, confusion, as well as exacerbation of epilepsy. In addition, use of the drug in therapeutic doses may lead to nausea, vomiting, diarrhea, stomach pain, vertigo, fever, low blood pressure, weight gain, anaphylactic reactions, angioedema, itching, dermatitis, urticaria and thrombophlebitis. If the dosage of the drug is exceeded, severe abdominal pain and bloody diarrhea may occur. In this case, patients are prescribed gastric lavage, induction of vomiting, hemodialysis, and also undergo symptomatic treatment. Particular caution when prescribing the drug should be exercised in case of impaired hemostasis, severe bleeding and extensive surgical interventions.

Instructions for use

First of all, it should be noted that the optimal dosage and duration of therapy using the drug Piracetam can only be prescribed by a qualified doctor. Using it on your own may not only not help, but also aggravate the situation, which can lead to serious consequences. As a rule, at the beginning of treatment, patients are prescribed the drug at a dosage of 800 mg three times a day before meals. After improvements appear, the single dose should be gradually reduced to 400 mg. The duration of the course of therapy can range from 14-20 days to 2-6 months. When using the drug for long-term treatment of psychoorganic syndrome in elderly patients, a dosage of 1.2-2.4 grams per day is prescribed. To treat the consequences of a coma, an initial dose of 9-12 grams per day is prescribed, and then a maintenance dose of three grams. The course of therapy is three weeks. For the treatment of alcoholism during the manifestation of alcohol withdrawal syndrome, in the initial period, take 12 grams of the drug per day, and then reduce the dose to 2.4 grams. At sickle cell anemia The daily dose of the drug is individual and is calculated as follows: 160 mg of the drug for each kilogram of the patient’s weight. All people using Piracetam should keep in mind that the last single dose must be taken no later than five o'clock in the afternoon. Otherwise, sleep disturbances may occur.

@ 2024 wowway.ru - Diets and nutrition. Diagnostics and tests. Medicines. Cholesterol. Atherosclerosis