Ringer's solution instructions for animals. Ringer's Locke - instructions for use, reviews, analogs and release forms (solution for infusion) medications for the treatment of alkalosis and correction of water-electrolyte balance in adults, children and pregnancy. Compound.


Instructions for use of Ringer-Locke solution for the treatment of animals
for dehydration and intoxication of the body, blood loss, as well as for washing eyes and wounds
(developer organization: Mosagrogen CJSC, Moscow)

I. General information
Trade name of the drug: Ringer-Locke solution (Solutio Ringer-Locke).
International nonproprietary name: Ringer-Locke solution.

Dosage form: solution for injection.
Ringer-Locke solution in 1 ml contains as active ingredients sodium chloride - 8 mg, potassium chloride - 0.2 mg, calcium chloride - 0.2 mg, sodium bicarbonate - 0.2 mg, glucose - 1 mg, and solvent - water for injection.
In appearance, the drug is a clear, colorless liquid.

Ringer-Locke Solution is produced in glass bottles of appropriate capacity, sealed with rubber stoppers reinforced with aluminum caps.
Store the medicinal product in the manufacturer's sealed packaging in a dry place, protected from direct sunlight, separately from food and feed, at a temperature of 0°C to 25°C.
The shelf life of the medicinal product, subject to storage conditions, is 2 years from the date of production.
It is prohibited to use the drug after its expiration date. Should be kept out of the reach of children.
Unused medicinal product is disposed of in accordance with legal requirements.

II. Pharmacological properties
Ringer-Locke solution refers to drugs that affect the water and electrolyte balance in the body. The drug is used as a rehydrating agent, to stabilize the water and electrolyte composition of the blood, and has a detoxifying effect.

In terms of the degree of impact on the body, Ringer-Locke solution is classified as a low-hazard substance (hazard class 4 according to GOST 12.1.007-76).

III. Application procedure
Ringer-Locke solution is used in animals for dyspepsia and other diseases accompanied by dehydration and intoxication of the body, blood loss, as well as for washing wounds and eyes.

A contraindication for the use of the drug is the individual hypersensitivity of the animal. In cases of severe impairment of renal excretory function, intravenous administration of Ringer-Locke solution is contraindicated.

Ringer-Locke solution is used subcutaneously or intravenously in the following doses:

Doses and timing of use depend on the weight of the animal and the course of the disease. For subcutaneous administration, the dose of the drug is administered fractionally to different places.

No overdose symptoms have been identified in animals.
The specific effects of the drug upon its first use and upon its withdrawal have not been established.

Use of the drug in large quantities can lead to the development of chloride acidosis and overhydration. In case of such complications, the dose is reduced or the drug is discontinued.

The use of Ringer-Locke Solution does not exclude the use of other medications.

Livestock products during and after the use of Ringer-Locke Solution are used without restrictions.

IV. Personal prevention measures
When working with Ringer-Locke Solution, you should follow the general rules of personal hygiene and safety precautions provided for when working with medications. After finishing work, wash your hands with warm water and soap.
In case of accidental contact of the drug with the skin or mucous membranes of the eye, they must be rinsed with plenty of water.
Empty drug bottles must not be used for household purposes; they must be disposed of with household waste.

Manufacturer: JSC "Mosagrogen"; 117545, Moscow, 1st Dorozhny proezd, 1.

Ringer-Locke solution is a perfusion and plasma replacement solution.

Available in the form of a liquid medicine. The solution is intended for infusion.

Ringer-Locke solution composition

The active ingredients included in the drug are: sodium chloride 9 grams, potassium chloride 0.2 g, sodium bicarbonate 0.2 g, calcium chloride 0.2 g, glucose 1 gram.

Excipient: water for injection.

Ringer-Locke solution is a colorless, transparent liquid.

Storage and release conditions

The drug should be stored in a place protected from light and away from children, at room temperature. The solution has a shelf life of two years.

In pharmacies, Ringer Locke solution is available by prescription.

Package

The solution is available in 200 ml bottles.

Pharmacology

Ringer-Locke solution contains a balanced mixture of the main blood cations in the concentrations required for it; it is physiological in comparison with isotonic sodium chloride solution 0.9%.

Ringer-Locke solution is able to restore the water-salt balance and replenish the fluid deficiency in the body that occurs during dehydration or due to the accumulation of extracellular fluid in areas of extensive trauma and burns, peritonitis, and abdominal operations.

Also, this drug can reduce the aggregation of formed elements, as well as blood viscosity. In addition, it improves the rheological properties of blood and tissue perfusion, while preventing the development of irreversible changes in tissues and increasing the effectiveness of blood transfusion measures in case of massive blood loss and severe forms of shock.

The drug has a detoxification effect by reducing the concentration of toxic products in the blood and activating diuresis.

Ringer-Locke solution instructions for use

– dehydration.

– shock, collapse, burns, freezing, vomiting, diarrhea.


– Dyspepsia and other diseases accompanied by dehydration and
intoxication.

- For blood loss.

– for washing wounds and eyes.

– As a general tonic in the treatment of various animal diseases.

Also used to dissolve various medications

Ringer-Locke solution

COMPOSITION AND FORM OF RELEASE Ringer-Locke solution - a combined drug in the form of a solution
for injection, containing 0.8 g of sodium chloride as active ingredients,
0.02 g potassium chloride, 0.02 g calcium chloride, 0.02 g sodium bicarbonate, 0.1
g glucose and water for injection as a solvent up to 100 ml.

A drug
is a colorless transparent sterile liquid. Released in the form
solution for injection packaged in glass bottles of 10, 20 and 100 ml.
The bottles are sealed with rubber stoppers and rolled with aluminum caps. Every
the packaging unit is marked indicating the manufacturing organization, name
medicinal product, volume in ml, batch number, expiration date, conditions
storage, method of use, inscriptions “For animals”, “Sterile” and
accompanied by instructions for use.

PHARMACOLOGICAL PROPERTIES Ringer-Locke solution is isotonic to animal blood plasma, regulates water-salt
and acid-base balance in the body of animals. After drug administration
quickly absorbed from the injection site and distributed in organs and tissues
animal. The drug does not irritate tissue.

DOSES AND METHOD OF ADMINISTRATION Ringer-Locke solution is used subcutaneously or intravenously in the following doses. At
subcutaneous administration, the dose of the drug is administered fractionally to different places. Horses, cattle 1000-3000 ml Small cattle 100-300 ml Calves up to one year 200-400 ml Lambs, piglets 25-100 Doses and timing of application depend on the weight of the animal and the course of the disease.

SIDE EFFECTS In recommended doses, the drug usually does not cause side effects in animals and
complications. Using the solution in large quantities can lead to the development
chloride acidosis, overhydration. In case of such complications, reduce the dose or
the drug is discontinued. The use of Ringer-Locke Solution does not preclude the use
other medicines.

CONTRAINDICATIONS Intravenous administration of the solution is contraindicated in case of severe impairment
excretory function of the kidneys.

SPECIAL INSTRUCTIONS Livestock products during and after use of the drug are used without
restrictions. When working with Ringer-Locke Solution, follow the general
rules of personal hygiene and safety precautions provided for when working with
medicines for animals.

STORAGE CONDITIONS in sealed manufacturer's packaging, dry, protected from direct sunlight
rays, out of the reach of children and animals, away from food and
feed at temperatures from 0 to 25 C. The shelf life of the drug is 2 years from the date
manufacturing. Do not use the medicine after finishing
its expiration date.

– dehydration.

Composition and release form

Solution for infusion 1 l

sodium chloride 8.6 g calcium chloride 0.33 g potassium chloride 0.3 g excipients: sodium hydroxide; hydrochloric acid; water for
injections.

sodium (Na) - 147 mmol,


potassium (K) - 4 mmol,

calcium (Ca2) - 2.25 mmol,

chloride (Cl−) - 155.6 mmol)

Theoretical osmolarity - 309 mOsmol

in plastic bottles of 500 ml; 1 bottle in a cardboard pack.

Description of dosage form: Transparent, colorless solution.

Pharmacological action Pharmacological action - replenishing the deficiency of energy substrates in
body. Compensation for the deficiency of extracellular fluid and basic electrolytes.

Indications of the drug Ringer's solutionDeficiency of extracellular fluid (if there is no need for compensation
red blood cells): shock, collapse, burns, freezing, vomiting, diarrhea.

Contraindications Decompensated heart failure, pulmonary edema, oliguria, anuria.

Method of administration and dosage IV, drip, at a dose of 500–1000 ml/day, average rate of administration - 3 ml/kg/h or
70 drops/min or 250 ml/h. The total daily dose is up to 2–6% of body weight.

Storage conditions for the drug Ringer's solution At a temperature of 15–25 ° C. Keep out of the reach of children.

The shelf life of the drug Ringer's solution is 3 years.

The solution is administered rectally to adults, 75-100 ml. To wash the eyes, nose, and wounds, use a sterile solution.

Ringer-Locke solution application and dosage

For intravenous administration of the solution by drip, the dosage is 50 ml - 3 l, at a rate of 4-8 ml/kg/h, depending on the complexity of the disease and the effectiveness of the detoxification and rehydration therapy.

special instructions

In case of long-term use of the solution in large volumes, the content of electrolytes and diuresis should be monitored.

Side effects

When using Ringer Locke solution in significant quantities, the development of chloride acidosis and hyperhydration may occur. In case of such complications, you need to reduce the dose or completely stop taking the drug.

Drug interactions

This solution is prescribed along with blood transfusions and blood plasma transfusions in order to increase the effectiveness of rehydration and detoxification therapy.

Ringer-Locke solution indications

Ringer-Locke solution is prescribed in cases of severe dehydration of various origins (infectious diseases accompanied by prolonged diarrhea and uncontrollable vomiting), acute massive blood loss, shock, extensive burns, severe postoperative period, toxic poisoning of various etiologies.

Contraindications

The administration of Ringer Locke solution intravenously is contraindicated in the case of thrombophlebitis, increased blood clotting, obvious impairment of the excretory function of the kidneys, as well as decompensated heart defects. It is not recommended to administer the drug in case of circulatory disorders, which are accompanied by pulmonary and cerebral edema, hypernatremia, hyperchloremia, metabolic alkalosis.

Cases of various types of intoxication in domestic and farm animals are, unfortunately, not uncommon. To alleviate the condition of patients in veterinary clinics in case of poisoning, a special type of drugs is used - designed to restore electrolyte levels. One such medicine is Ringer's solution. Instructions for using this particular product, which has earned good reviews from consumers, will be discussed below in the article.

In veterinary medicine, this remedy is used quite often. This solution can be used for cats, dogs, rabbits and other animals.

Release form and composition

This product is supplied to veterinary clinics and pet stores in the form of a solution intended for injection. It is a colorless transparent liquid. The substances in the Ringer-Locke solution include the following:

  • sodium bicarbonate;
  • sodium chloride;
  • potassium chloride;
  • calcium chloride hexahydrate.

Distilled water is used as a solvent in the preparation of this solution. This medicine is supplied to the market in sealed sterile bottles of 100 or 200 ml.

Features of the drug

This remedy is usually used in the same cases as an isotonic solution of sodium chloride (table salt). However, it is also more physiological and closer to blood plasma. This feature of the drug also explains the high degree of effectiveness of its action.

After injection, Ringer-Locke solution is quickly absorbed and distributed into the tissues of the animal. At the same time, it does not have any irritating effect on the animal’s body. The positive effect provided by this drug is primarily due to the fact that it is able to quickly normalize the water-salt and acid-base balance.

Indications for use

According to the instructions, Ringer-Locke solution can be administered to animals:

  • for dysentery, vomiting, diarrhea and food poisoning;
  • various types of thermal injuries - frostbite, burns;
  • inflammation of the peritoneum;
  • intestinal obstruction;
  • bites from poisonous spiders or snakes;
  • blood loss.

In addition, it is used for plasmapheresis.

Since Ringer's solution is compatible with many veterinary medications, it is often used as a solvent in the treatment of other medications. But the combination of drugs in this case should, of course, be selected exclusively by a specialist. This solution should not be used simultaneously with certain medications.

Directions for use and safety precautions

The instructions recommend using Ringer's solution only for intravenous infusion. Sometimes this medicine is also used as an external remedy. Thus, it is used, for example, for washing wounds and mucous membranes if necessary.

In some cases, Ringer's for animals allows it to be administered intramuscularly. But injections of this medicine are usually given in this way when treating only kittens, rabbits and puppies, and if the animal is actually very ill. In young veterinary patients, finding thin veins is, unfortunately, often very difficult.

Ringer's solution does not belong to the class of harmful and dangerous substances. However, when using it, of course, you should adhere to the standard technology for using veterinary drugs. Injections of this medicine, for example, must be done wearing medical gloves.

Instructions for use of Riegner-Locke solution: dosage of the drug

You cannot prescribe this medicine to an animal on your own. Treatment is carried out only after visiting the clinic on the recommendation of a veterinarian. Only specialists usually inject this medicine into animals. In this case, the veterinarian chooses the dosage of Ringer’s solution depending on the specific disease and the weight of the animal.

For adult cats, for example, the drug is usually used in an amount of 100-150 ml per day. In this case, its single dose is 50 ml.

Contraindications for use

Ringer-Locke solution helps animals with intoxication very well. But, unfortunately, this remedy cannot be used to treat cats, rabbits, horses, dogs, etc., in all cases. According to the instructions for use of Ringer-Locke solution, it cannot be prescribed if the animal has, for example, problems such as:

  • swelling of tissues or brain;
  • heart failure;
  • anuria;
  • oliguria;
  • severe kidney damage.

In case of edema, this drug can aggravate the situation of the animal. The use of the drug in this case often even leads to death. Among other things, when this remedy is used in the body of cats, dogs, etc., blood flow accelerates. In heart failure, the drug can therefore actually be very harmful. In this case, the heart may simply not cope with the increased blood flow. And this, in turn, unfortunately, can lead to the death of a pet.

Ringer-Locke solution should be used with caution, according to the instructions, for acidosis, hypovolemia and other similar diseases.

Side effects

Ringer's solution belongs to the group of safe drugs. No side effects are usually observed when treated with it in animals. Only occasionally can pets experience allergic reactions to this medicine. In this case, the drug should, of course, be stopped.

Of course, when using this product you must strictly follow the dosage. If too much medication is administered to an animal, it may experience chloride acidosis and overhydration. If an animal develops such conditions, the dose of the drug it takes should be reduced or the solution should be discontinued altogether.

Analogues of the drug

The instructions for using Ringer's solution are described above. In veterinary medicine, this medicine is used very often. And this remedy helps animals very well against intoxication. At the same time, Ringer's solution is inexpensive. The price for a bottle of the product in veterinary pharmacies is usually no more than 50-60 rubles. But of course, if necessary, this drug can be replaced with some of its analogues.

For example, the following drugs have the same therapeutic effect as Ringer-Locke solution:

  • "Regidron", produced in powder form and intended for oral use. This medicine is usually used to treat dehydration in animals due to diarrhea.
  • This remedy is used in approximately the same cases and in the same dosages as the Ringer-Locke solution.

Instructions for use of Ringer-Locke solution for the treatment of animals
for dehydration and intoxication of the body, blood loss, as well as for washing eyes and wounds
(developer organization: Mosagrogen CJSC, Moscow)

I. General information
Trade name of the drug: Ringer-Locke solution (Solutio Ringer-Locke).
International nonproprietary name: Ringer-Locke solution.

Dosage form: solution for injection.
Ringer-Locke solution in 1 ml contains as active ingredients sodium chloride - 8 mg, potassium chloride - 0.2 mg, calcium chloride - 0.2 mg, sodium bicarbonate - 0.2 mg, glucose - 1 mg, and solvent - water for injection.
In appearance, the drug is a clear, colorless liquid.

Ringer-Locke Solution is produced in glass bottles of appropriate capacity, sealed with rubber stoppers reinforced with aluminum caps.
Store the medicinal product in the manufacturer's sealed packaging in a dry place, protected from direct sunlight, separately from food and feed, at a temperature of 0°C to 25°C.
The shelf life of the medicinal product, subject to storage conditions, is 2 years from the date of manufacture.
It is prohibited to use the drug after its expiration date. Should be kept out of the reach of children.
Unused medicinal product is disposed of in accordance with legal requirements.

II. Pharmacological properties
Ringer-Locke solution refers to drugs that affect the water and electrolyte balance in the body. The drug is used as a rehydrating agent, to stabilize the water and electrolyte composition of the blood, and has a detoxifying effect.

In terms of the degree of impact on the body, Ringer-Locke solution is classified as a low-hazard substance (hazard class 4 according to GOST 12.1.007-76).

III. Application procedure
Ringer-Locke solution is used in animals for dyspepsia and other diseases accompanied by dehydration and intoxication of the body, blood loss, as well as for washing wounds and eyes.

A contraindication for the use of the drug is the individual hypersensitivity of the animal. In cases of severe impairment of renal excretory function, intravenous administration of Ringer-Locke solution is contraindicated.

Ringer-Locke solution is used subcutaneously or intravenously in the following doses:

Doses and timing of use depend on the weight of the animal and the course of the disease. For subcutaneous administration, the dose of the drug is administered fractionally to different places.

No overdose symptoms have been identified in animals.
The specific effects of the drug upon its first use and upon its withdrawal have not been established.

Use of the drug in large quantities can lead to the development of chloride acidosis and overhydration. In case of such complications, the dose is reduced or the drug is discontinued.

The use of Ringer-Locke Solution does not exclude the use of other medications.

Livestock products during and after the use of Ringer-Locke Solution are used without restrictions.

IV. Personal prevention measures
When working with Ringer-Locke Solution, you should follow the general rules of personal hygiene and safety precautions provided for when working with medications. After finishing work, wash your hands with warm water and soap.
In case of accidental contact of the drug with the skin or mucous membranes of the eye, they must be rinsed with plenty of water.
Empty drug bottles must not be used for household purposes; they must be disposed of with household waste.

Manufacturer: JSC "Mosagrogen"; 117545, Moscow, 1st Dorozhny proezd, 1.

It just so happens that dogs, due to the specific nature of their use by humans, are quite often poisoned. The reason may be either your pet’s addiction to eating at the nearest landfill or his work activities. In any case, intoxication must be treated urgently. And Ringer-Locke solution for dogs can be a suitable help in this difficult task.

This is the name of the water-salt composition. It contains glucose, sodium bicarbonate, calcium and sodium chloride. Please note that you can also find a simple Ringer's solution on sale, which does not contain glucose. In principle, there is no particular difference between them. It’s just that if you need more support for the liver during treatment, glucose needs to be introduced into the body separately.

What can this drug be used for in principle? Firstly, as mentioned above, for almost all types of poisoning. “Ringer” is especially indicated for salts of heavy metals, since calcium chloride, which is part of this drug, transforms them into an insoluble state. The same applies to allergic reactions, since the same component significantly reduces the porosity of blood vessels and prevents the release of histamine and the liquid component of blood from the vessels. Of course, its effect in this case is not as pronounced as that of a pure solution of calcium chloride.

This medicine is very important in treating dehydration and eliminating its consequences. Since this composition is almost similar in its properties to blood plasma, the body accepts it easily and without any consequences. By the way, what volume of Ringer-Locke solution can be infused into a dog’s body? The question is quite complicated, since in this case everything depends on the size and weight of the dog. For small animals, the normal daily dose is one hundred milliliters maximum, but large dogs (St. Bernards, Great Danes) with severe dehydration may need 300-400 milliliters (sometimes more). In general, the dosage depends solely on the veterinarian and is selected based on the type of disease, its course, and the condition of the animal itself at the time of providing therapeutic care.