Use of troxevasin. Troxevasin gel - official instructions for use Troxevasin pharmacological group
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Troxevasin is a drug from the group of angioprotectors that has the property of strengthening the capillary wall, thereby reducing its permeability and the fragility of small blood vessels. Thanks to its angioprotective effect, Troxevasin effectively eliminates manifestations of venous insufficiency, relieves edema, relieves inflammation and improves the tone of the smooth muscle elements of the vein walls, and also reduces the severity of trophic disorders in soft tissues associated with insufficient functional activity of microvessels.Troxevasin may be produced by other companies under the name Troxerutin, but despite the different names, they are the same drug. Therefore, in the further text of the article we will use the name “Troxevasin” to refer to drugs, remembering that everything stated applies equally to drugs sold under the name “Troxerutin”.
Names, varieties, release forms and composition of Troxevasin
Currently, there are two main types of Troxevasin on the pharmaceutical market:1. Troxevasin.
2. Troxevasin Neo.
Troxevasin is available in two dosage forms - capsules for oral administration And gel for external application . Troxevasin Neo exists in a single form - gel for external application . The differences between Troxevasin and Troxevasin Neo are that the second drug (Neo) contains several active components, while the first contains only one. Therefore, Troxevasin Neo gel has a slightly more pronounced effect compared to Troxevasin.
Gel Troxevasin and Troxevasin Neo are often called ointment, but this is incorrect. The drug is not available in ointment form. However, often people, not knowing the exact name of the dosage form for external application, refer to it as an ointment. In this case, they mean Troxevasin gel, since there is no ointment.
Capsules for oral administration Troxevasin are often called tablets, which is also incorrect. However, at the everyday level, people know that they need a form for oral administration, and as a rule these are tablets, and therefore Troxevasin is given the name tablets, not capsules. That is, when someone talks about Troxevasin tablets, they mean capsules, since there are no other forms for oral administration.
The composition of the gel and capsules includes Troxevasin as an active component troxerutin. In the gel, the concentration of the active substance is 2%, that is, each 1 g contains 20 mg of troxerutin. Each capsule contains 300 mg of active substance. The active components of the Troxevasin Neo gel include troxerutin (20 mg per 1 g), heparin (1.7 mg per 1 g) and dexpanthenol (panthenol) (50 mg per 1 g). The auxiliary components of Troxevasin and Troxevasin Neo are shown in the table.
Troxevasin capsules have a hard gelatin shell of a cylindrical shape, colored yellow. Inside the capsules there is a powder colored yellow or yellow-green. Sometimes the powder cakes into fairly large pieces, which easily fall apart when crushed with your fingers. Capsules are available in packs of 50 and 100 pieces.
Troxevasin gel is transparent, yellow or light brown. Available in aluminum tubes of 40 g. Troxevasin Neo gel is also transparent or almost transparent, but is colored yellowish or greenish-yellow. Also available in 40 g tubes.
Therapeutic effects of Troxevasin
The therapeutic effects of Troxevasin are provided by troxerutin, which is part of it, which has the following effects: - Venotonic effect;
- Angioprotective effect;
- Anti-inflammatory effect;
- Anti-edema effect;
- Antioxidant action.
Angioprotective effect is to strengthen the vascular wall and increase its resistance to adverse environmental influences. Thanks to this effect, the vessels can withstand much greater loads without being damaged, but continuing to function effectively.
Anti-inflammatory effect consists in stopping the inflammatory process in the venous wall and in the soft tissues surrounding it (muscles, ligaments, etc.).
Anti-edema effect consists in reducing the swelling of peripheral tissues associated with excessive sweating of the liquid part of the blood from veins with insufficient tone.
Antioxidant action consists of neutralizing free radical molecules that damage the cells of the vascular wall, thereby making it thin, weak and easily permeable. That is, due to the antioxidant effect, the amount of damage to the vein walls is reduced.
Thanks to the listed effects, Troxevasin in relation to small blood vessels (capillaries) has the following therapeutic effect:
- Reduces capillary fragility;
- Reduces capillary permeability;
- Strengthens the walls of capillaries;
- Reduces the severity of the inflammatory process in the capillary wall;
- Reduces platelet adhesion to the inflamed capillary wall and, accordingly, prevents the formation of blood clots;
- Improves microcirculation and tissue nutrition;
- Relieves swelling;
- Reduces pain associated with inflammation and swelling of capillaries and surrounding tissues;
- Reduces the severity of symptoms of chronic venous insufficiency.
Troxevasin Neo gel, in addition to troxerutin, contains heparin and dexpanthenol, which provide the drug with a number of additional therapeutic effects. That is, Troxevasin Neo has all of the above effects of Troxevasin, and in addition to them several more.
So, heparin has a powerful anticoagulant effect, which provides a reliable and pronounced antithrombotic effect. That is, Troxevasin Neo is much better than Troxevasin in preventing the formation of blood clots and intensifying microcirculation. Dexpanthenol is a precursor of vitamin B5, and provides excellent and rapid regeneration of damaged tissues, and also improves the absorption of heparin.
Troxevasin (gel, capsules) and Troxevasin Neo (gel) - indications for use
Both dosage forms of Troxevasin and Troxevasin Neo gel are indicated for use for the same diseases and conditions. However, in case of moderate or severe pathological changes, it is recommended to carry out a course of treatment with simultaneous ingestion of Troxevasin capsules and external application of Troxevasin or Troxevasin Neo gel to the skin. If pathological changes in tissues are mild or moderate, then only Troxevasin and Troxevasin Neo gel can be used. Since Troxevasin Neo gel has a stronger antithrombotic and reparative effect compared to Troxevasin, it is recommended for use in thrombophlebitis, periphlebitis and trophic ulcers. For these conditions, Troxevasin Neo gel is the drug of choice, and in all other cases, any type of medication can be used.
So, the indications for the use of Troxevasin and Troxevasin Neo capsules and gel are the following conditions and diseases:
- Relief of symptoms of chronic venous insufficiency (pain, swelling, heaviness, feeling of fullness and fatigue in the legs, spider veins and spider veins, cramps and paresthesia);
- Phlebeurysm;
- Superficial thrombophlebitis and periphlebitis;
- Phlebothrombosis;
- Postphlebilitic syndrome;
- Trophic disorders due to venous insufficiency (pale skin, formation of bruises and hematomas, poor and slow wound healing, etc.);
- Dermatitis caused by varicose veins;
- Trophic ulcers associated with chronic venous insufficiency;
- Haemorrhoids;
- Swelling, pain and bruising after soft tissue injuries;
- Hemorrhagic diathesis;
- Conditions in which there is increased capillary permeability (for example, acute viral infections such as influenza, scarlet fever, etc.);
- Paresthesia (impaired sensitivity in the form of goosebumps, etc.) on the lower extremities at night and after waking up;
- Cramps of the calf muscles at night;
- Diabetic angiopathy and retinopathy;
- Side effects of radiation therapy;
- As an auxiliary drug for restoring the functioning of blood vessels after sclerotherapy of veins and removal of varicose nodes, including hemorrhoids;
- To improve microcirculation as part of complex therapy for diabetes mellitus, hypertension and atherosclerosis;
- Venous insufficiency and hemorrhoids during pregnancy, starting from the 13th week of gestation.
Instructions for use
Troxevasin gel (ointment) and Troxevasin Neo - instructions for use
Troxevasin and Troxevasin Neo gels are applied to the skin with gentle massaging movements until completely absorbed, twice a day - morning and evening. If necessary, after applying and absorbing the gel into the skin, you can put on compression garments (stockings, stockings, tights) or wrap elastic bandages. Troxevasin can also be used under compresses. Do not apply the gel to damaged areas of the skin (open wounds), mucous membranes or eyes. Additionally, Troxevasin Neo should not be administered into the vagina or rectum. Remember that both types of gel are intended for external use on the skin only.
In order to obtain a pronounced therapeutic effect, Troxevasin gel should be applied to the skin regularly for a long period of time until swelling, pain, heaviness and a feeling of fullness in the legs completely disappear. The success of therapy depends on the regularity and duration of use of the gel.
After swelling and other manifestations of venous insufficiency have passed, you can stop using Troxevasin gel. If symptoms reoccur, it is necessary to start the course of gel therapy again and continue it until the condition is completely normalized and the painful manifestations of the disease disappear.
Similar courses of using Troxevasin gel can be carried out an unlimited number of times throughout life. However, you should follow a simple rule - when symptoms disappear, stop using the gel, and when they appear, start using the drug again.
Troxevasin Neo should be used in a course lasting 2–3 weeks, but no more. During the year, you can conduct no more than 2 - 3 courses with intervals between them of 4 - 5 months.
If the severity of the symptoms of the disease does not decrease within 6 to 7 days of regular use of any type of drug, then you should consult a doctor.
Elderly people can use the gel without restrictions.
In order to enhance the therapeutic effect for venous insufficiency, the gel can be combined with taking Troxevasin capsules orally. If the gel is used for diseases accompanied by increased capillary permeability (influenza, scarlet fever and other viral infections), then to enhance its therapeutic effect it is necessary to additionally take ascorbic acid (vitamin C) orally.
Troxevasin capsules (tablets) – instructions for use
Capsules should be taken with meals, swallowed whole, without biting or allowing the powder to spill out in other ways, and with a sufficient amount of water (200 ml). In the first 1 to 2 weeks of therapy, you should take 1 capsule (300 mg) 3 times a day. Then, when the therapeutic effect develops fully and the symptoms decrease, you should switch to taking Troxevasin capsules in a maintenance dosage. If the symptoms of venous insufficiency were very severe, then the maintenance dosage is the same as the initial one, that is, the drug should continue to be taken 1 capsule 3 times a day for 3 to 4 weeks. If the symptoms were moderate or mild, then the maintenance dosage is 600 mg per day, that is, the drug should be continued to be taken 1 capsule 2 times a day.
That is, the scheme for using Troxevasin capsules is two-stage. At the first stage, for 1 to 2 weeks, all people need to take 1 capsule 3 times a day in order to quickly reduce the severity of symptoms. At the second stage, a person must either continue taking Troxevasin at the same dosage as in the first stage, or reduce it to 600 mg, drinking 1 capsule 2 times a day for another 3 to 4 weeks. Thus, the total duration of treatment with Troxevasin capsules, consisting of two stages, is 1 – 6 weeks.
In addition, treatment with Troxevasin capsules can be interrupted after completion of the first stage. In this case, the therapeutic effect will last for approximately 4 weeks.
Troxevasin gel can also only provoke allergic reactions (urticaria, eczema, dermatitis) as side effects.
Troxevasin capsules when taken orally can cause the following side effects:
- Nausea;
- Erosive and ulcerative lesions of the mucous membranes of the digestive tract;
- Skin rash;
- Hives;
- Eczema;
- Dermatitis;
- Headache;
- Tides.
Contraindications for use
Gel Troxevasin and Troxevasin Neo are contraindicated for use in the following diseases or conditions:- Infected wounds with suppuration;
- Copious exudation from an open wound;
- Age under 18 years (for Troxevasin Neo);
- I trimester of pregnancy (for Troxevasin).
- Peptic ulcer of the stomach and duodenum in the acute phase;
- Gastritis in the acute phase;
- Hypersensitivity to any components of the drug;
- Hypersensitivity to rutosides.
Troxevasin - analogues
Both Troxevasin and Troxevasin Neo have synonymous drugs and analogues on the pharmaceutical market. Synonyms include medications containing exactly the same active substances as Troxevasin or Troxevasin Neo. And analogues include drugs containing other active substances, but having the most similar spectrum of therapeutic activity.A synonym for Troxevasin Neo is Venolife gel, and simply Troxevasin is Troxerutin gel.
Analogs of Troxevasin and Troxevasin Neo are the same following drugs:
- Antistax capsules;
- Ascorutin and Ascorutin D tablets;
- Vasoket tablets;
- Venabos gel;
- Venarus tablets;
- Venitan forte gel;
- Venolek tablets;
- Venoruton gel, capsules and effervescent tablets;
- Ginkor gel;
- Detralex tablets;
- Diosmin tablets;
- Lyoton 1000 gel;
- Rutin tablets;
- Trombless and Trombless Plus gel;
- Phlebodia 600 tablets;
- Phlebofa tablets;
- Yuglanex extract for oral administration.
Troxevasin
Latin on rank: Troxevasin
Pharmacological groups:
H35.0 Background retinopathy and reti on natural vascular changes. I79.2 Peripheral angiopathy in diseases classified elsewhere. I80 Phlebitis and thrombophlebitis. I80.0 Phlebitis and thrombophlebitis of the superficial vessels of the lower extremities. I83 Varicose veins of the lower extremities. I83.0 Varicose veins of the lower extremities with ulcers. I84 Hemorrhoids. I87.0 Postphlebitic syndrome. I87.2 Venosis on I failure (chronic) (peripheral). L98.4.2 Trophic skin ulcer. R52.0 Acute pain. R60.0 Localized edema. T08-T14 Injury to an unspecified part of the trunk, limb, or area of the body. T14.0 Surface on I have an injury to an unspecified area of the body. T14.3 Dislocation, sprain and damage to the capsular-ligamentous apparatus of a joint of an unspecified area of the body
pharmachologic effect
Active ingredient (INN) Troxerutin (Troxerutin)
Application: Chronic venosis on insufficiency with such manifestations as static heaviness in the legs, leg ulcers, trophic skin lesions; varicose veins, incl. during pregnancy, thrombophlebitis, periphlebitis, post-thrombotic syndrome, hemorrhoids, post-traumatic edema and hematomas, hemorrhagic diathesis with increased capillary permeability, capillary toxicosis (including measles, scarlet fever on, influenza), diabetic microangiopathy, retinopathy, vascular side effects of radiation therapy; as a prophylactic after surgery on ve on X.
Contraindications: Hypersensitivity, ulcers on I have stomach disease and two on duodenum, chronic gastritis (in the acute phase).
Side effects: In some cases, erosive and ulcerative lesions of the gastrointestinal tract, allergic reactions (skin on I rash).
Interaction: Enhances the effect of ascorbic acid on structure and permeability of the vascular wall.
Directions for use and dosage: Inside (during meals), intramuscularly, intravenously, locally. Inside - on chawl on I dose 2 caps. 0.3 g each; for maintenance therapy - 1 caps. in a day. The course of treatment is 2–4 weeks. For intravenous and intramuscular injections, a 10% solution is used, in ampoules - 5 ml, 5 ml are administered every other day, for maintenance therapy the drug is used in capsules. For topical use 2% is recommended gel, which on wear an even thin layer morning and evening on the affected area from distal to proximal parts, gently rubbing until completely absorbed into the skin. The gel can also be used for on application of compresses.
- Troxevasin
Gardex baby cream gel
pharmachologic effect
Active ingredient (INN) Diethyltoluamide
Application: Prevention of blood-sucking bites on insects.
Directions for use and dosage: Locally. Treat exposed parts of the body, clothing, on scales and grids on OK on x, canopy.
Precautionary measures: Avoid ingestion and on mucous membranes.
- Gardex children's cream-gel (-)
Dr. Theiss Nova figure gel
Latin on rank: Dr. Theiss Nova figura gel
Pharmacological groups: Dermatotropic agents
Nosological classification (ICD-10): L98.9 Lesion of skin and subcutaneous tissue, unspecified. R23 Other skin changes
Composition and release form:
Pharmachologic effect:Dermatoprotective.
Recommended: For cellulite, to care for problem areas of the skin (abdomen, thighs, buttocks), helps reduce fat deposits.
Contraindications: No.
Side effects: Not identified.
Directions for use and dosage:Locally. Apply on skin morning and evening and rub with rotational movements until
- Dr. Theiss Nova figura gel
Ginkor gel
Latin on rank: Ginkor gel
Pharmacological groups: Angioprotectors and microcirculation correctors
Composition and release form: 100 g of gel contain 0.14 g ginkgo biloba extract and troxeruti on 3 g, in tubes of 40 g, in a cardboard box 1 tube.
Directions for use and dosage: Locally. Apply in small quantities (a column of gel equivalent in volume to a hazelnut is sufficient to treat the back of the shin) on the affected area 2-4 times a day and lightly massage.
- Ginkor gel
Active ingredient (INN) Rutoside (Rutoside)
Application: Varicose veins, superficial thrombophlebitis, chronic venosis on I insufficiency (pain, swelling, trophic on lesions, ulcers, etc.), hemorrhoids, post-thrombotic syndrome, retinopathy (diabetic, hypertensive, atherosclerotic), lymphostasis, trophic on damage after radiation therapy, pain and swelling in injuries ( gel).
Contraindications: Hypersensitivity.
Restrictions on use: Pregnancy (1st trimester).
Side effects: Dyspeptic symptoms, headaches on I have pain, hot flashes, allergic rashes on skin, local skin reactions ( gel).
Directions for use and dosage: Orally, during meals, forte tablets - 1 tablet. (for retinopathy - 1–2 tablets) 2 times a day; capsules - 2–3 capsules. per day.
Externally, gel on wear on skin 2 times a day and rub in with light massaging movements. After symptoms disappear (usually after 2-4 weeks), treatment should be continued for several more weeks.
- Rutoside (-)
Active ingredient (INN) Zinc hyaluronate on t (Zinc hyaluronate)
Application:Solution: poorly healing infected wounds, trophic ulcers, bedsores, fistulas.
Gel: all types of mild and moderate acne (including comedonal and papulopustular acne).
Contraindications: Hypersensitivity.
There are no data on use during pregnancy and lactation.
Side effects: A burning sensation at the application site (in on beginning of treatment); a feeling of skin tightening and hyperemia of the skin (when using the gel).
Interaction: No data.
Overdose: No data.
Directions for use and dosage: Locally. Solution: after washing the wound with 3% hydrogen peroxide solution or saline solution directly on drops on the wound surface on the solution is carried. It is possible to cover it with a gauze cloth of the appropriate size. The dressing must be changed 1-2 times a day.
Gel: evenly on wear on thoroughly cleanse the skin with a thin layer 2 times a day.
Special instructions: After opening the bottle on The solution is recommended to be used within 4 weeks. The gel does not have photosensitizing properties and does not stain skin or underwear.
- Zinc hyaluronate (-)
Solcoseryl injection solution
Latin on rank: Solcoseryl
Pharmacological groups: Angioprotectors and microcirculation correctors. Antihypoxants and antioxidants. Regenerants and reparants
Composition and release form: 1 ml of injection solution contains standardized deproteinized hemodialysate from the blood of healthy dairy calves 42.5 mg, in ampoules of 2 ml; 5 pcs in a blister, 5 blisters in a cardboard box.
1 g ointment - 50 mg; in tubes of 20 g, in a cardboard box 1 tube.
1 g of gel - 100 mg; in tubes of 20 g, in a cardboard box 1 tube.
1 g of eye gel - 200 mg; in tubes of 5 g, in a cardboard box 1 tube.
Directions for use and dosage: IM or IV - 2–5 ml of solution per day.
IV, as an infusion, slowly - 5–10 ml of Solcoseryl solution in 250 ml of physiological solution.
Externally - ointment and gel; on wear in a thin layer on damaged surface 2-3 times a day.
Ophthalmic gel instill 1 drop into the eye from a tube carried
- Solcoseryl injection solution (Solcoseryl)
Kikko - gel for massage
Pharmacological groups: Dermatotropic agents
Nosological classification (ICD-10): R23.8.1 Increased on I have skin sensitivity
Composition and release form: Kikko - gel for massage contains calendula, chamomile extract, olive oil; in tubes of 100 ml.
Kikko - cream with a calming effect for irritation - chamomile extract, milk, hawthorn, lanolin; in tubes of 100 ml.
Kikko - moisturizing cream - avocado oil, olive oil, milk extract, chamomile; in tubes of 100 ml.
Kikko - ointment with a calming effect for irritation - chamomile extract, wheat germ oil, olive oil, bisabolol; in a package of 75 ml (in the form of a pencil).
Kikko - softener powder - milk extract, corn silk; per package 50 g.
Characteristic: Cosmetic products for skin care of infants and young children of the “Infinite Dolcezze” series of the “Chicco” brand.
Pharmachologic effect:Dermatotropic.
Component properties: The massage gel moisturizes and tones the baby's skin. A cream with a calming effect in case of irritation prevents the appearance of redness and diaper dermatitis, has a dermatoprotective effect ( on natural proteins of milk and wheat). Moisturizing cream nourishes and protects the skin from cold and wind, prevents redness and flaking (leaves on skin a thin protective film, not on destroying the natural hydrolipid balance of the skin). An ointment with a calming effect on irritation contains zinc oxide and on natural proteins that prevent irritation and infection of sensitive areas of the child’s skin. Softener powder softens the water during the baby’s first baths and reduces skin irritation.
Directions for use and dosage:Kikko - gel for massage: on wear on the baby's skin with soft massaging movements.
Kikko - cream with a calming effect on irritation: on wear on baby's skin.
Kikko - moisturizing cream: on wear on clean skin 20 minutes before going out on street.
Kikko - ointment with a calming effect on irritation: on wear directly on baby's skin.
Kikko - powder softener: added to the water during the first baths but
- Kikko - massage gel (-)
Dr. Theiss Arnica
Latin on rank: Dr. Theiss Arnica
Pharmacological groups: Local irritants
Nosological classification (ICD-10): L08.0 Pyoderma. L29 Itching. L55 Sunburn. T14.0 Surface on I have an injury to an unspecified area of the body. T14.3 Dislocation, sprain and damage to the capsular-ligamentous apparatus of a joint of an unspecified area of the body. W57 Bite or sting, non-venomous on insects and other non-venomous arthropods. Z50.8 Assistance with other types of rehabilitation procedures
Composition and release form:
in jars of 20 and 50 g; 1 jar in a box.
in tubes of 100 ml; 1 tube in a box.
Pharmachologic effect:Local irritant, anti-inflammatory, antibacterial, analgesic, regenerating.
Pharmakodi on mika: Annoys recipe ors of the skin and subcutaneous formations, promotes the formation and release of enkephalins, endorphins (regulating pain, vascular permeability), histamine, kinins and other physiological stimulants of immunological processes, activates local blood flow and accelerates the resorption of hemorrhages. The gel has a pleasant cooling effect.
Indications:Ointment: sprains, injuries (without ruptures), pustular skin diseases, itching, bites on insects, minor burns (from sunlight); as a means for massage (sports on I'm medicine on).
Gel: bruises, sprains, injuries and abrasions, physical on loads, muscle pain, bites on insects, to relieve tired legs, for sports massage.
Contraindications: Hypersensitivity.
Side effects: With prolonged use - blistering dermatitis on damaged areas of the skin.
Directions for use and dosage:Locally. Ointment and gel rub into the skin of the affected area several times a day, in addition, gel rubbed into the skin with elements of massage before and after physical exercise on
- Dr. Theiss Arnica
Rheuma- gel
Latin on rank: Rewma-Gel
Pharmacological groups: Homeopathic remedies. Not on arcotic a on medicinal drugs, including non-steroidal and other anti-inflammatory drugs
Nosological classification (ICD-10): G54.1 Lesions of the lumbosacral plexus. M05-M14 Inflammatory polyarthropathy. M15-M19 Arthrosis. M54.3 Sciatica. M54.4 Lumbago with sciatica. M60 Myositis. M79.1 Myalgia. T14.3 Dislocation, sprain and damage to the capsular-ligamentous apparatus of a joint of an unspecified area of the body
Composition and release form:
in tubes of 35 and 50 g; in a cardboard pack 1 tube.
Description of the dosage form: Tan transparent gel.
Characteristic: Homeopathic medicine.
Pharmachologic effect:Anti-inflammatory, analgesic, decongestant, improves local blood circulation.
Indications: Rheumatic and degenerative diseases of muscles and joints, painful on muscle strains and strains, lumbago (pain in the lumbosacral spine) as part of complex therapy.
Contraindications: Hypersensitivity to individual components, incl. To Rhus toxicodendron(poison sumac shoots); children's age up to 1 year.
Use during pregnancy and breastfeeding: It can be used during pregnancy and breastfeeding if the expected effect of therapy exceeds the potential risk to the fetus (child).
Side effects: In rare cases, allergic reactions (skin itching, rashes).
Interaction: The use of homeopathic medicines does not exclude the use of other medicines.
Directions for use and dosage:Locally, adults and children over 1 year old on wear on painful areas, lightly rubbing into the skin, 3 times a day. Long-term use is possible.
Precautionary measures: When using homeopathic medicines in on During treatment, temporary deterioration is possible. In this case, you should stop taking it and consult a doctor.
- Rewma-Gel
In this article you can read the instructions for use of the drug Troxevasin. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Troxevasin in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Troxevasin in the presence of existing structural analogues. Use for the treatment of varicose veins, thrombophlebitis, hematomas and bruises in adults, children, as well as during pregnancy and breastfeeding.
Troxevasin- a remedy for the treatment of chronic venous insufficiency. It is a derivative of routine.
It has P-vitamin activity, participates in redox processes, blocks hyaluronidase, stabilizes hyaluronic acid in cell membranes and reduces their permeability.
Normalizes the permeability of capillary walls, increases their tone. Increases the density of the vascular wall, reduces exudation of the liquid part of the plasma and diapedesis of blood cells. Reduces exudative inflammation in the vascular wall, limits the adhesion of platelets to its surface.
For chronic venous insufficiency, use is recommended both in the initial and late stages of the disease. As a result of treatment, the feeling of heaviness in the legs disappears, swelling of the lower extremities decreases, and trophism improves. In conditions characterized by increased vascular permeability and disruption of their structure (including scarlet fever, influenza, measles, allergic reactions), it is used in combination with ascorbic acid to enhance its effects.
Pharmacokinetics
Well absorbed from the skin surface when used externally (gel).
When taken orally, it is well absorbed from the gastrointestinal tract. Easily passes histohematic barriers. Metabolized in the liver to form two metabolites. It is excreted by the kidneys and bile (11% unchanged) during the day.
Indications
- chronic venous insufficiency with such manifestations as static heaviness in the legs, leg ulcers, trophic skin lesions;
- phlebeurysm;
- superficial thrombophlebitis;
- periphlebitis;
- phlebothrombosis;
- varicose dermatitis;
- postthrombotic syndrome;
- hemorrhoids;
- post-traumatic edema and hematomas;
- hemorrhagic diathesis with increased capillary permeability;
- capillary toxicosis (including measles, scarlet fever, influenza);
- diabetic microangiopathy;
- retinopathy;
- vascular side effects of radiation therapy;
- as a prophylactic after vein surgery.
Release forms
Capsules 300 mg.
Gel for external use 2%.
The drug does not exist in the form of tablets or ointments; dosage forms in this form are possibly counterfeit.
Instructions for use and dosage
Capsules
Orally (during meals) - 0.3-0.9 g for 2-4 weeks or more, maintenance therapy - 0.3 g/day.
Gel
A 2% gel is used locally, which is applied evenly in a thin layer in the morning and evening to the affected area from the distal to the proximal part, gently rubbing until completely absorbed into the skin. The gel can also be applied under an occlusive dressing.
Side effect
- skin rash;
- erosive and ulcerative lesions of the gastrointestinal tract;
- headache.
Contraindications
- hypersensitivity;
- peptic ulcer of the stomach and duodenum;
- chronic gastritis (in the acute phase);
- Long-term use is not recommended for patients with severe renal impairment;
- children under 15 years of age (no experience of use).
Use during pregnancy and breastfeeding
Contraindicated in the 1st trimester of pregnancy and during breastfeeding; in the 2nd and 3rd trimesters of pregnancy it can only be used as prescribed by a doctor.
special instructions
The gel is applied only to an intact surface and is not used on open wounds. Avoid contact of the gel with the eyes and mucous membranes. After applying the gel, it is necessary to avoid exposure to sunlight on the treated areas.
Drug interactions
Strengthens the effect of ascorbic acid on the structure and permeability of the vascular wall.
Analogues of the drug Troxevasin
Structural analogues of the active substance:
- Troxevenol;
- Troxerutin;
- Troxerutin VetProm;
- Troxerutin Vramed;
- Troxerutin Zentiva;
- Troxerutin Lechiva;
- Troxerutin-MIC.
If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.
- Composed of one capsules product includes 300 mg troxerutin . Additional components: titanium dioxide, lactose monohydrate, quinoline yellow dye, magnesium stearate, sunset yellow dye, gelatin.
- Contains 1 g. gel (troxevasin ointment) 2% for external use includes 20 mg troxerutin . Additional components: trolamine, disodium edetate dihydrate, benzalkonium chloride, water.
Release form
Gelatinous, cylindrical, yellow capsules(sometimes erroneously called Troxevasin tablets), yellow-green powder inside, possible presence of conglomerates. 10 capsules in a blister, 5 or 10 blisters in a cardboard pack.
Light brown gel. 40 grams in an aluminum tube - one tube in a cardboard pack or 40 grams in a plastic tube - one tube in a cardboard pack.
pharmachologic effect
Venoprotective and venotonic effect.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
Wikipedia describes the active substance as angioprotector , which acts mainly on capillaries and veins.
Narrows the pores between cells endothelium vessels due to changes in the fibrous matrix between endothelial cells. Suppresses aggregation and increases the degree of deformability of red cells, has an anti-inflammatory effect.
In case of chronic insufficiency of venous function, it reduces the strength of trophic disorders, seizures , pain , varicose ulcers . Relieves symptoms associated with – pain and bleeding .
Favorable effect on capillary permeability and resistance helps slow down progression diabetic retinopathy . The abstract indicates that the drug affects the rheological parameters of the blood and helps prevent microthrombosis of the retinal veins.
Pharmacokinetics
After taking the capsule orally, absorption reaches an average of 10-15%. The highest concentration in the blood occurs approximately 2 hours after consumption; a therapeutically significant level remains in the plasma for 8 hours. The drug is metabolized in the liver. 20% is excreted unchanged in urine and 60-70% in bile.
When the gel is applied to the affected area, the active component quickly penetrates through, after half an hour it is found in the dermis, and after 3-5 hours - in the subcutaneous tissue.
Indications for use of Troxevasin
Indications for use of capsules:
- postphlebitic syndrome ;
- chronic insufficiency of venous function;
- tissue nutritional disorders with;
- component of adjuvant therapy after sclerotherapy veins and venectomies ;
- trophic ulcers;
- (itching, exudation, pain, bleeding);
- haemorrhoids And venous insufficiency at (from 2nd trimester);
- a component of auxiliary therapy for retinopathy in those suffering and against the background.
The use of Troxevasin ointment is justified for:
- varicose veins ;
- chronic insufficiency of the hair dryer function with swelling and pain in the lower extremities, a feeling of fatigue and heaviness in the legs, convulsions , ;
- varicose dermatitis;
- periphlebitis;
- pain and swelling of a post-traumatic nature (sprains, bruises).
Contraindications for Troxevasin
Contraindications for capsules:
- in the acute phase;
- exacerbation;
- to the components of the product or to rutosides .
With caution, it is necessary to use Troxevasin in tablets (capsules) for a long time when .
Contraindications for Troxevasin gel:
- violation of skin integrity;
- hypersensitivity to the components of the product.
Side effects
- Digestive reactions: nausea , damage to the digestive organs of an erosive-ulcerative nature, .
- Other reactions: , rash, hot flashes.
Side effects disappear immediately after cessation of therapy.
Instructions for use of Troxevasin (Method and dosage)
Troxevasin capsules, instructions for use
In the initial period of treatment, take 300 mg of the drug three times a day. The effect usually develops within 15 days, then treatment is continued at the above dose or reduced to the lowest maintenance dose of 600 mg, it is also possible to suspend further therapy. In the latter case, the achieved effect usually lasts for at least a month. The course of therapy is approximately 3-4 weeks; the need for a longer course is determined individually in each individual case.
During treatment diabetic retinopathy the medicine is prescribed in a dosage of 900-1800 mg per day.
How to take Troxevasin capsules
Capsules (tablets) are taken orally, swallowed whole and washed down with water during meals.
Gel Troxevasin, instructions for use
The instructions for Troxevasin ointment indicate that this form of release is used externally, for which the ointment (cream) is applied to the affected area twice a day in the morning and evening, lightly rubbing until completely absorbed. If necessary, the gel can be applied under elastic stockings or bandages. The results of treatment with the drug depend on its regular use over a long period of time.
Overdose of the drug in gel form
Due to external use and the wide therapeutic range of the drug, there is no danger of an overdose. If a large volume of gel is unintentionally swallowed, it is necessary to take general measures to evacuate the drug from the body (induce vomiting) and consult a doctor.
Interaction
The effects of the drug are enhanced when used together with .
Terms of sale
On prescription.
Storage conditions
Keep away from children. Store in a dry, dark place at room temperature. The cream (gel) must not be frozen.
Best before date
For Troxevasin capsules – 5 years. For ointment for varicose veins in an aluminum tube - 5 years, in a plastic tube - 2 years.
special instructions
If there is no relief of symptoms while using the drug, you should consult your doctor.
Troxevasin foot ointment is allowed to be applied only to the intact surface of the skin.
Avoid contact of the drug with open wounds and mucous membranes.
For lesions characterized by increased vascular permeability (for example, with , allergic reactions, ), Troxevasin gel is used together with ascorbic acid to stimulate its effect.
Analogues of Troxevasin
Level 4 ATX code matches:
Troxevasin and its analogues are usually comparable in price. Troxerutin - the most common and cheapest analogue of the described drug, the release forms of which are ointments and capsules. Lyoton gel - a more expensive substitute for Troxevasin. There are also tablets with similar systemic effects: Avenue, Venorin .
The price of analogues of troxevasin ointment is almost always cheaper or approximately equal to the price of the indicated product.
For children
There are no data on the results of using the drug for children under 14 years of age.
Is the ointment suitable for children?
Troxevasin gel can be used to treat children only as prescribed by a doctor.
Newborns
This drug is not used to treat this category of patients.
Alcohol
Alcohol should not be consumed at the same time as the medicine.
Troxevasin during pregnancy and lactation
Data on the use of the drug Troxevasin gel during pregnancy in the 1st trimester are not provided.
The instructions provide for the possibility of using the drug in all forms of release (ointment, capsules) in the 2nd and 3rd trimesters only as prescribed by a doctor and taking into account all risks, including hemorrhoids during pregnancy.
During lactation, the use of the drug is also possible only under the conditions described above.
Reviews of the use of the product during these periods do not report the occurrence of side effects.
Reviews about Troxevasin
Reviews of Troxevasin capsules (tablets) and reviews of Troxevasin gel are not fundamentally different and indicate that the drug helps well against varicose veins , from bruises, and is also used for the face with a pronounced vascular pattern on the skin. The drug is also recommended for the prevention of specific venous diseases during pregnancy.
Reviews from doctors for hemorrhoids also indicate good results in the treatment of this disease in the compensation stage. Troxevasin is widely used as an ointment for hemorrhoids.
The question of the effectiveness of Troxevasin is often discussed: does it help with varicose veins ? In the treatment of this disease, only multicomponent complex therapy will be effective, including the use of compression stockings and adherence to a work-rest regime.
Troxevasin or Troxerutin – which is better? How are these drugs different?
Troxerutin is the active ingredient in both drugs and there is no fundamental difference between them. The differences are only in the form of release and price. The choice should be made based on the individual characteristics of the patient and economic considerations.
Which is better: Troxevasin or Lyoton?
Lyoton And Troxevasin contain different active ingredients. The first does not have a direct effect on the veins, but only removes blood clots and prevents their occurrence. The drugs have slightly different indications, so when choosing, you should follow your doctor’s recommendations.
Troxevasin or Detralex – which is better?
The drugs are analogues. The difference is that Detralex It is based on natural raw materials, is produced only in the form of tablets, and its price is almost twice as expensive as Troxevasin. The choice between these medications should be made based on the doctor’s recommendations, individual response to the drug and economic considerations.
Troxevasin and Troxevasin Neo - differences
Due to the changed composition Troxevasin Neo additionally has anticoagulant, regenerating and metabolic effects and is available only in gel form. The indications for the drugs are identical, but the action of the latter allows you to more fully cover the spectrum of symptoms characteristic of venous diseases.
Treatment of rosacea on the face with Troxevasin
The drug is often used on the face when spider veins appear, but it is worth remembering that rosacea may be a symptom of more serious diseases of the internal organs. Therefore, before self-medicating, you need to be examined by a dermatologist and therapist.
Troxevasin for hemorrhoids
Reviews of the gel for hemorrhoids indicate the low effectiveness of the drug when used as monotherapy and during exacerbations of severe forms of this disease. How to use Troxevasin ointment from hemorrhoids, and in combination with which drugs to use in the treatment regimen, a proctologist will best advise. Capsules at hemorrhoids also never used in isolation from concurrent anti-inflammatory and hemostatic treatment (including suppositories and injectable drugs).
Troxevasin price, where to buy
Price of Troxevasin capsules
The average price of a package of drug No. 50 in Russia is 325-395 rubles; in Moscow the price is comparable to the Russian average and is also characterized by a large range of values.
The cost of such packaging in Ukraine ranges from 94 to 115 hryvnia, depending on the region: in the city of Kharkov it is 100-109 hryvnia, in Zaporozhye - 93-97 hryvnia, in Odessa - 95-112 hryvnia.
How much does Troxevasin gel cost?
The price of Troxevasin gel 40 grams in Russia is 170-180 rubles. The average price of Troxevasin ointment (troxevasin ointment) in Ukraine is 46-53 hryvnia. For comparison, analog candles Relief No. 12 for the treatment of hemorrhoids in Russia cost about 275 rubles.
- Online pharmacies in Russia Russia
- Online pharmacies in Ukraine Ukraine
- Online pharmacies in Kazakhstan Kazakhstan
ZdravCity
Troxevasin capsules 300 mg No. 50 Balkanpharma
Troxevasin NEO gel 40g Balkanpharma-Troyan AD
Troxevasin capsules 300 mg No. 100Balkanpharma-Razgrad AD
Troxevasin gel 2% 40g Balkanpharma
Pharmacy Dialogue * discount 100 rub. by promo code medside(for orders over 1000 rub.)
Troxevasin Neo gel (tube 40g)
Troxevasin (caps. 300 mg No. 50)
Excipients: carbomer - 6 mg, trolamine (triethanolamine) - 7 mg, disodium edetate dihydrate - 0.5 mg, - 1 mg, purified water - 965.5 mg.
40 g - aluminum tubes (1) - cardboard packs.
40 g - laminate tubes (plastic) (1) - cardboard packs.
pharmachologic effect
Troxevasin is a flavonoid (rutin derivative). Has P-vitamin activity; has venotonic, venoprotective, decongestant, anti-inflammatory, anticoagulant and antioxidant effects. Reduces the permeability and fragility of capillaries, increases their tone. Increases the density of the vascular wall, reduces exudation of the liquid part and diapedesis of blood cells.
Reduces inflammation in the vascular wall, limiting the adhesion of platelets to its surface.
Pharmacokinetics
When the gel is applied to the affected area, the active substance quickly penetrates the epidermis, after 30 minutes it is found in the dermis, and after 2-5 hours in the subcutaneous fatty tissue.
Indications
- varicose veins;
— chronic venous insufficiency with symptoms such as: swelling and pain in the legs; feeling of heaviness, fullness, fatigue of the legs; spider veins and spider veins, paresthesia;
- thrombophlebitis;
- periphlebitis;
- varicose dermatitis;
- pain and swelling of a traumatic nature (with bruises, sprains, injuries).
Contraindications
— violation of the integrity of the skin;
- hypersensitivity to the drug.
Dosage
The gel is applied to the affected area 2 times a day in the morning and evening, gently rubbing until completely absorbed. If necessary, the gel can be applied under bandages or elastic stockings.
The success of treatment with the drug largely depends on its regular use over a long period of time.
It is recommended to combine it with taking Troxevasin capsules to enhance the effect. If the symptoms of the disease worsen or do not go away after 6-7 days of daily use of the drug, the patient should consult a doctor.
Side effects
Overdose
Due to the external method of use and the large therapeutic breadth of the drug, there is no danger of overdose. If you accidentally swallow a large amount of gel, you must take general measures to remove the drug from the body (emetics) and consult a doctor. If indicated, peritoneal dialysis is performed.
Drug interactions
Currently, there is no data on drug interactions with Troxevasin.
special instructions
The gel is applied only to an undamaged surface.
Avoid contact with open wounds, eyes and mucous membranes.
In conditions characterized by increased vascular permeability (including scarlet fever, influenza, measles, allergic reactions), the gel is used in combination with to enhance its effect.
Impact on the ability to drive vehicles and operate machinery
Troxevasin gel does not affect the ability to drive a vehicle or operate moving machinery.
Pregnancy and lactation
There is no data regarding undesirable effects on the fetus and newborn when using the drug.
Conditions for dispensing from pharmacies
The drug is approved for use as a means of OTC.
Storage conditions and periods
The drug should be stored out of the reach of children, in a dry place, protected from light, at a temperature not exceeding 25°C. Do not freeze. The shelf life for the drug in an aluminum tube is 5 years, in a laminate (plastic) tube - 2 years.