Syrup "Ascoril": instructions for use for children and cough medicines. Instructions for use of ascoril syrup for children Ascoril tablets instructions for use

Ascoril (salbutamol + bromhexine + guaifenesin) is a combined bronchodilator and expectorant drug, the “visiting card” of the Indian pharmaceutical company GLENMARK PHARMACEUTICALS. Salbutamol has the most favorable safety profile of all selective alpha-2-adrenergic stimulants. It effectively eliminates bronchospasm, while simultaneously turning the ciliated epithelium of the bronchi into an active state and facilitating the evacuation of sputum from the bronchial tree. Bromhexine makes sputum less thick by breaking down sputum-forming substances - mucoproteins and mucopolysaccharides. In addition, bromhexine restores the reproduction of surfactant, which ensures the normal functioning of the bronchi and lungs and facilitates the penetration of simultaneously prescribed antibiotics into the lung tissue. Guaifenesin also thins mucus, allowing it to be removed from the respiratory tract. Menthol, which is part of the preparation as an aid, relieves hypertonicity of the smooth muscles of the bronchi, has a calming effect, relieves irritation of the mucous membrane of the respiratory tract and acts as a disinfectant. Such a diverse action of Ascoril eliminates the need for the simultaneous appointment of several drugs at once, which ensures high compliance (patient adherence to treatment). Favorable safety profile, lack of toxicity, as well as the pleasant taste of the syrup allows the use of Ascoril in pediatric practice in children older than 3 years. The results of multicenter randomized clinical trials indicate the high efficiency of the use of Ascoril in children suffering from bronchial asthma and other diseases of the respiratory tract (incl.

h. catarrhal), accompanied by a decrease in the lumen of the bronchi.

One of the key links in the pathogenesis of the development of respiratory diseases is the disruption of the mucociliary system due to the low activity of the ciliated epithelium of the bronchi against the background of excessive reproduction of sputum or changes in its consistency towards increased viscosity. Violation of the patency of the respiratory tract and congestion in it lead to pulmonary insufficiency and create favorable conditions for the development and progression of inflammatory processes. Ascoril, which contains both mucolytic and mucokinetic active ingredients, allows you to successfully act on several pathogenetic links at once, which ensures the effectiveness of its use in the treatment of a wide range of respiratory diseases. The drug is well tolerated by patients and allows to achieve a stable positive effect by increasing the bronchial throughput. Ascoril can be used both in monotherapy mode and as part of the combined treatment of diseases of the respiratory system, accompanied by bronchial obstruction. Ascoril should not be taken in conjunction with codeine-containing drugs, as well as other antitussive drugs, because. the latter suppress the cough reflex, as a result of which the evacuation of sputum is difficult. During the course of medication using Ascoril, alkaline drinks should not be taken. Salbutamol, which is part of the drug, when combined with diuretics, is more capable of exhibiting a hypokalemic effect.

Pharmacology

The combined drug has a bronchodilator, expectorant and mucolytic effect.

Salbutamol is a bronchodilator that stimulates β 2 -adrenergic receptors of the bronchi, blood vessels and myometrium. Prevents or eliminates bronchospasm, reduces resistance in the airways, increases the vital capacity of the lungs. Causes expansion of the coronary arteries, does not lower blood pressure.

Bromhexine is a mucolytic agent that has an expectorant and antitussive effect. Increases the serous component of bronchial secretion; activates the cilia of the ciliated epithelium, reduces the viscosity of sputum, increases its volume and improves discharge.

Guaifenesin is a mucolytic agent that reduces the surface tension of the structures of the bronchopulmonary apparatus; stimulates the secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acid mucopolysaccharides, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of an unproductive cough into a productive one.

Pharmacokinetics

Salbutamol

When taken orally, absorption is high. Food intake reduces the rate of absorption, but does not affect bioavailability. Communication with plasma proteins - 10%. Penetrates through the placenta.

It undergoes first pass metabolism in the liver and in the intestinal wall, by means of phenol sulfotransferase it is inactivated to 4-o-sulfate ester. T 1 / 2 - 3.8-6 hours. Excreted by the kidneys (69-90%), mainly in the form of an inactive phenol sulfate metabolite (60%) for 72 hours and with bile (4%). The bioavailability of orally administered salbutamol is about 50%.

Bromhexine

When taken orally, it is almost completely (99%) absorbed from the gastrointestinal tract within 30 minutes. Bioavailability - low (the effect of the primary "passage" through the liver). Penetrates through the placental barrier and the BBB.
In the liver, it undergoes demethylation and oxidation, and is metabolized to the pharmacologically active ambroxol. T 1/2 - 15 hours (due to slow reverse diffusion from tissues). Excreted by the kidneys. In chronic renal failure, excretion of metabolites is impaired. With repeated use, it can accumulate.

Guaifenesin

Absorption from the gastrointestinal tract is fast (25-30 minutes after ingestion). T 1/2 - 1 hour Penetrates into tissues containing acidic mucopolysaccharides.
Approximately 60% of the administered drug is metabolized in the liver. Excreted by the lungs (with sputum) and kidneys both unchanged and in the form of inactive metabolites

Release form

Tablets are white, round, flat, beveled, scored on one side.

Excipients: calcium hydrogen phosphate, corn starch, methyl parahydroxybenzoate (methyl paraben), propyl parahydroxybenzoate (propyl paraben), purified talc, colloidal silicon dioxide, magnesium stearate.

10 pieces. - cellular contour packings (1) - packs of cardboard.
10 pieces. - cellular contour packings (2) - packs of cardboard.

Dosage

inside. Adults and children over 12 years of age are prescribed 1 tab. 3 times / day.

Children aged 6 to 12 years old - by? or 1 tab. 3 times / day.

Overdose

Symptoms: increased manifestations of side effects.

Treatment: symptomatic therapy.

Interaction

Other beta 2-agonists and theophylline increase the effect of salbutamol and increase the likelihood of side effects.

Ascoril is not prescribed simultaneously with preparations containing codeine and other antitussives, as this makes it difficult to expel liquefied sputum.

Bromhexine, which is part of the Ascoril preparation, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.

Ascoril salbutamol, which is part of the drug, is not recommended for patients who receive MAO inhibitors.

Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.

Side effects

Rarely: when used in high doses, headache, dizziness, irritability, sleep disturbance, drowsiness, tremor, convulsions, nausea, vomiting, diarrhea, exacerbation of gastric and duodenal ulcers, palpitations, pink urine may be observed , allergic reactions (rash, urticaria), collapse, bronchospasm.

Cough is an unpleasant symptom that makes parents worry and look for ways to save their child from the painful effects of such a manifestation. Parents should be warned right away, trips to the pharmacy with a request to give something for coughing end up with the fact that the cough does not go away, and taking drugs bought at random does not bring a therapeutic effect, and sometimes even harms.

Pharmacists, without specifying the problem, advise tablets, syrups and medicines that are stored on the “cough” shelf, and the buyer, taking into account his capabilities, takes the remedy that his financial capabilities allow. This approach to treatment is simply terrifying, especially when it comes to the health of children.

In this article, we will consider the instructions for using Ascoril syrup for children.

Introduction

Cough is only a small clue in the diagnosis, therefore, only a doctor should decide which remedy is suitable for a child.

All antitussive medicines are used to eliminate dry or wet cough. With a dry cough, the main task of therapy is to transform it into a wet state, and then sputum will easily leave the respiratory tract. With a wet cough, sputum should be removed, and the tracheobronchial tree should be released from the load.

Sometimes a dry cough is treated with drugs that calm the brain, where the signals responsible for the cough reflex come from.

Watching children, pediatricians state that dry cough is poorly tolerated by babies, because. it "exhausts", makes the child restless and capricious, and is sometimes complicated by asthma attacks. With a wet cough, most children feel satisfactory.

In our article we will talk about cough syrup with the trade name Ascoril Expectorant, which is manufactured by the Indian company Glenmark Pharmaceuticals Ltd. We will find out what recommendations exist, according to the instructions for use, and highlight the main parameters under which Ascoril syrup is recommended for children.

Ascoril is a combination drug, each component of which complements each other, providing a pronounced mucolytic, bronchodilator (relieves bronchospasm) and expectorant effect.

The active substances of ascoril are as follows:

guaifenesin (100 mg) - thins viscous sputum;
bromhexine (4mg) - suppresses cough shocks, makes sputum less thick, removes it from the bronchi, enhances the antibacterial effect;
salbutamol - expands the bronchi, thereby relieving obstruction and asthma attacks.

The syrup is available in bottles of 100 and 200 ml. Ascoril has a pleasant taste with bitterness and a beautiful orange tint, although children do not always take it with pleasure.

You should not be guided by the price of the syrup indicated in some instructions for use, because. it is constantly changing, and it should also be borne in mind that the same syrup is suitable for children as for adults (there is no separate children's form), so we buy the product based only on volume.

To date, the optimal price for ascoril (syrup) with a volume of 100 ml is 300 rubles, and for a bottle of 200 ml - about 400-450 rubles.

The first thing parents are interested in is at what age can Ascoril syrup be taken? According to the instructions, unlike tablets, the syrup is approved for use after a year.

From a year to 6 years, the syrup is recommended for 5 ml (teaspoon) 2-3 times a day. From the age of six, the dose increases and is 10 ml (tablespoon) three times a day. Depending on the nature and intensity of the cough, the pediatrician adjusts the dosage and duration of administration (usually up to 7 days). Syrup is often recommended between feedings.

As for the main indications, they are as follows:

bronchitis;
tracheobronchitis;
emphysema;
tuberculosis;
pleurisy;
whooping cough;
bronchopneumonia;
pneumonia;
cystic fibrosis - a genetic systemic hereditary disease;
COB (chronic obstructive bronchitis) during an exacerbation;
pneumoconiosis;
bronchial asthma (exacerbation).

Important! Ascoril is not prescribed for the common cold and viral infection. It is characterized by only strict indications, especially a tendency to sputum difficult to separate, dry unproductive cough and obstructive processes in the bronchi. Therefore, ascoril is not a remedy that can be used uncontrollably, such as pertussin or licorice syrup. Ascoril is prescribed by a pulmonologist or an experienced pediatrician.

Contraindications and adverse reactions

Like any drug, ascoril has its own limitations for use, they are as follows:

cardiac and vascular diseases (arrhythmias, heart disease (aortic stenosis), hypertension, tachycardia, myocarditis);
hormonal pathologies (diabetes mellitus (decompensated form), thyrotoxicosis, hyperthyroidism);
ulcerative and inflammatory processes in the stomach;
severe pathologies of the liver and kidneys;
children's age up to 12 months (only for syrup), for tablets - up to 6 years;
ascoril is not compatible with cough center blockers;
individual immunity of the composition of ascoril.

As a result of the use of syrup, the following side effects are sometimes observed:

urine staining in a pinkish hue;
collapse;
increased heart rate;
convulsions;
bronchospasm;
tremor;
trembling in the limbs;
excitation;
nausea or vomiting;
stomach bleeding;
skin rash;
headache;
other.

If the child is at risk, and Ascoril syrup is contraindicated for him, then safer analogues are selected as an alternative, which we will talk about a little later.

The list of contraindications and side effects is quite impressive, so such information should not scare parents, but warn against amateur treatment. Unfortunately, many people like to use fast-acting remedies right away, without thinking that at the right time, they will have to seek help from even more complex drugs.

The main rule in treatment! Any therapy is prescribed with safe means: herbal preparations, homeopathy and folk recipes.

If the baby has a cold, there is a slight cough, then you should always start with the simplest methods, such as: warm drinks, rubbing, warming compresses, and only if they are ineffective, resort to drug therapy.

Cheap analogues of Ascoril - list

Structural analogues of ascoril are Indian syrups: Cashnol from Sedate Halsker and Lorcof (Biomedicare).

They are also available in volumes of 100 and 200 ml, and are much cheaper than ascoril. The cost of 100 ml of cashew is 160 rubles, and for 200 ml you will have to pay 270 rubles. The price of lorcof needs to be specified, because there are not always deliveries to Russian pharmacies.

These funds differ in the ratio between the active components, in the composition of the excipients, as well as in the age limit (cashnol and lorcoff are used only from the age of three).

The remaining analogues have only a similar therapeutic effect, but their composition is completely different. Here is a list of analogues (in syrup), which are recommended to be used if ascoril is contraindicated, they are as follows:

erespal (150 ml) - 250 rubles;
ambroxol hexal (100 ml) - 100 rubles;
broncholithin (125 g) - 90 rubles;
lazolvan (100 ml) - 200 rubles;
ambrobene (100 ml) - 120 rubles.

The above analogues are also prescribed only by a doctor, because. indications for their use require medical supervision.

Parents always want a speedy recovery for their children, so it's no surprise that they scour the internet for the best and most effective cough syrups and mixtures. Most often, they are interested in the question of choosing one or another remedy, but rather, what is better, for example, erespal or ascoril? Let's and we will try to compare several analogues with ascoril.

Comparative evaluation of ascoril, erespal, lazolvan, ambrobene and ambroxol

Each instruction for the drug highlights the composition, indications, contraindications and side effects - these are the main criteria that characterize medicines. When comparing analogues, based on these instructions, the pros and cons of the drugs in question are selected.

These tools "work" in completely different ways. Erespal eliminates inflammation and swelling, and ascoril helps to remove sputum and relieve bronchospasm. But, each in its own way frees the airways from coughing and other related manifestations.

If the child has a prolonged cough, subfebrile temperature, it is better to use Erespal. With difficulty breathing, as well as suffocation - ascoril. Ascoril contains salbutamol, which effectively expands the bronchi.

Askoril is cheaper than Erespal, but this is not a reason to change it. Therefore, these drugs can be called relative analogues, and it is not entirely appropriate to compare them. Often, pulmonologists prescribe ascoril and erespal together, including them in complex therapy.

Ascoril has more contraindications and adverse reactions. It is used from 12 months of age, and erespal only from the age of two.

Ambroxol or ascoril - what to choose?

Ambroxol is a structural analogue of ambrobene, so it is not advisable to do a comparative analysis again. The only advantage of Ambroxol is its low price. The price for 100 ml of syrup produced in Russia is in the range of 50-60 rubles.

It is impossible to say for sure which analogue is better, each clinical case requires its own drug, but its selection is the prerogative of the doctor, and nothing else.

Syrup "Ascoril" - reviews of parents on the use of medicine for children

Reviews about the drug are different, but this is normal, because. any drug is suitable individually.

Alla

I have two children (7 and 9 years old). They fell ill alternately with a difference of 5 days. My son has pneumonia, and a week later my daughter has bronchitis. Our dad has bronchial asthma, probably, and in children the respiratory system is weak.

The doctor prescribed an antibiotic (injections), erespal and ascoril for his son. Literally two days later, the son began to expectorate a lot of mucus, and the temperature dropped sharply. Prior to this, he did not sleep well at night, because. I had severe pain in my chest and back.

I asked the doctor if it was possible for my daughter to use ascoril, to which a negative answer followed. My daughter was prescribed sumamed for three days and ambroxol.

I think that the doctor correctly approached the treatment.

Nataliya

My son is 12 years old, began to cough, and suddenly I accidentally find out that he smokes about 15 cigarettes a day. There is practically no sputum when coughing, it appears in the form of seizures, more often at night. We turned to the Institute of Pulmonology, where they underwent diagnostics. X-ray showed chronic bronchitis, and spirometry - spasm of large bronchi. The temperature is about 37 degrees in the evenings. There was a feeling of constriction in the chest.

The doctor prescribed treatment: macrofoam, ascoril, inhalations with cedar ethers. We did not see any significant improvement in the week of treatment. We will change the specialist, although first you need to quit smoking - this is a fact.

Valeria

My feedback about ascoril is positive. The child is allergic, and from early childhood, now my son is 3 years old. When the baby catches a cold, a wild cough begins, from which I come into shock. Recently had tracheobronchitis. The pediatrician prescribed inhalations with berodual and ascoril syrup.

The effect was already on the first day. The sputum came out perfectly, and there was no specific whistling when breathing. Askoril drank three times a day. For 7 days they were completely healthy. Yes, I forgot, they drank augmentin (antibiotic).

Best Cough Medicines

Conclusion

At first glance, cough syrup may seem like a simple medicine, to which you should not pay much attention. Bought cough syrup and good. But, this is not true. The composition is always important, where active substances can be used only for complicated forms of the disease.

The instructions for use are a hint, the main thing is to carefully subtract each line. But such advice is only suitable in cases where the doctor is not available to patients. Be healthy!

Ascoril is classified as a drug that thins sputum, relaxes smooth muscles in the bronchial tree, and provides an expectorant effect. Is it allowed to be treated with Ascoril in childhood? How often is the drug given to young patients and how long does such treatment last? How to give syrup to a child correctly - before or after a meal? Let's analyze these and other questions about the use of Ascoril in children.

Release form

Ascoril is produced in the form of a syrup packaged in 100 ml or 200 ml bottles. It is an orange transparent liquid with a pleasant taste and a specific aroma. A solid form of Ascoril is also produced, which is a round white tablet on which there is a risk (the tablet can be divided according to it). One package contains 10, 20 or 50 pieces.

Compound

Among the additional components, menthol is the most valuable. In addition, compounds such as citric acid, glycerol, sucrose, yellow dye, pineapple and blackcurrant flavors, sodium benzoate, sorbic acid, purified water, sorbitol and propylene glycol are added to the syrup.

The active ingredients in Ascoril tablets are the same, and in addition, to obtain a solid form, propylparaben, Mg stearate, purified talc, Ca hydrogen phosphate, corn starch, methylparaben and silicon dioxide were added to the preparation.

You may find it useful to watch a video in which Dr. Komarovsky talks in detail about such a common childhood illness as coughing:

Operating principle

The influence of Ascoril on the human body is due to the therapeutic effect of each of its components:

Salbutamol has the ability to relax smooth muscles located in the walls of the bronchi, due to the stimulation of adrenergic receptors. Thanks to this action, the medicine eliminates the spasm of the bronchial tree or prevents its occurrence. Since salbutamol affects beta 2 adrenoreceptors, among the effects caused by taking Ascoril there is not only relaxation of the bronchi and improvement of their patency, but also dilation of blood vessels. This component also has a positive effect on lung capacity.
The main action of bromhexine is mucolytic. This Ascoril ingredient helps with coughing, making sputum less thick and also increasing its volume. In addition, this compound activates the ciliated epithelium in the bronchi. As a result, mucus leaves the bronchial tree faster (better expectoration).
The action of guaifenesin is also to reduce the viscosity of sputum and increase its amount.. Also, this component of the drug activates the sections of the bronchi responsible for removing mucus from the bronchial tree.
The menthol added to Ascoril in syrup is also noted for its ability to relax the bronchi and soothe a cough. This component helps to activate the secretion of glands in the bronchial tree, and also has an antiseptic effect.

Indications

The reason to prescribe Ascoril is often a broncho-pulmonary disease., in which there are difficulties with sputum separation. The drug is prescribed:

With tracheobronchitis.
Any kind of bronchitis.
With asthma.
With laryngotracheitis.
With pneumonia (inflammation of lung tissue) caused by any pathogen.
With obstructive pulmonary disease.
In whooping cough, when the patient has a violent spasmodic cough which is worse at night.
With emphysema.
With tuberculosis infection of the lungs.
With cystic fibrosis.

At what age is it allowed to take?

In pediatrics, Ascoril in the form of a syrup is used in children who are 1 year old. At 6 months and another age up to a year, such a medicine is not prescribed. But even if the child is older, for example, he is already 3 years old, the use of Ascoril syrup should be very careful.

If the drug is given with a wet cough, then the excess sputum formed in the respiratory tract will only worsen the baby's condition. But with a dry cough, when the mucus in the bronchi is too thick and viscous, Ascoril will become an effective help (make the cough productive). As for Ascoril tablets, they are not given until the age of 6.

Contraindications

The medicine is not prescribed:

If the child has a hypersensitivity to any of its ingredients.
If the patient has high blood pressure, myocarditis is diagnosed, the heart rhythm is disturbed, or aortic stenosis is detected.
If the child's thyroid function is elevated.
If glaucoma is detected.
If a small patient has gastric bleeding or an exacerbated peptic ulcer.
If the baby has diabetes in the stage of decompensation.
If kidney function is severely impaired or liver failure is detected.

With remission of peptic ulcer or compensated diabetes mellitus, Ascoril should be used with caution.

Side effects

There is an allergy to the active or auxiliary substances of Ascoril, for example, in the form of a skin rash or itching.
The urine of a child treated with Ascoril may acquire a pink tint, which should not cause anxiety.
The nervous system of a child may react to taking Ascoril with sleep disturbance, headache, drowsiness, tremor of the body or limbs, excitability and even convulsions.
Treatment with Ascoril can provoke diarrhea, nausea, bloating and other symptoms of dyspepsia.
Under the influence of Ascoril, a biochemical blood test is unreliable.
The drug can cause a decrease in blood pressure, as well as an increase in heart rate.
In very rare cases, when taking Ascoril, there is a spasm of the bronchi, retraction of the wings of the nose, severe pallor and dry wheezing in the lungs. This is a paradoxical reaction to the drug, which is due to individual intolerance.

Watch a video interview with a practicing pediatrician about mucolytic drugs used in pediatrics:

Instructions for use and dosage

The syrup should be drunk after a meal in about 30-60 minutes. The medicine is given three times a day. It is better to drink the product with water, and liquids such as milk with the addition of soda or mineral water can reduce the therapeutic effect of Ascoril due to the presence of alkalis.
Syrup dosage for a child under six years of age is 5 ml per dose, and children aged from 6 to 12 years, liquid Ascoril can be given both 5 and 10 ml at a time. Children 12 years and older are offered an adult dosage, which is 10 ml of syrup per 1 dose.
Ascoril tablets should also be drunk some time after a meal with a non-alkaline liquid. A single dose for children is half a tablet, which is given twice a day. If necessary, the frequency of receptions increases up to three times a day.
How many days to drink Ascoril expectorant? The most common course of treatment with this drug lasts 5 or 7 days, but sometimes the doctor prolongs the period of application of Ascoril.

Overdose

Interaction with other drugs

If you use Ascoril together with other drugs that act on the same adrenergic receptors, for example, with Berodual, Anaprilin, Ventolin, Propranolol or Clenbuterol, then their therapeutic effect will increase, but side effects will manifest themselves to a greater extent.
The appointment of Ascoril together with glucocorticoids or diuretics will provoke a decrease in the level of potassium in the blood.
The drug should not be combined with antidepressants, which are classified as MAOIs.
The simultaneous use of Ascoril and antitussive drugs (especially those based on codeine) will interfere with sputum production and worsen the child's condition.
The addition of Ascoril treatment with Macropen, Cefazolin and some other antibiotics will contribute to a greater penetration of such antimicrobial agents into the lung tissue.

Terms of sale

To buy Ascoril Expektorant or tablet form of medicine in a pharmacy, you need a prescription from a doctor. The price of 100 ml of syrup is on average 300 rubles, and a bottle of 200 ml is about 400 rubles. A pack of 10 tablets costs about 240 rubles.

Storage conditions and shelf life

The place where Ascoril is planned to be stored must be ventilated, dry and away from sunlight. Do not keep the drug where a small child can easily get to it. It is desirable that the air temperature in the place chosen for storage does not exceed the limit of +25°C. Both syrup and tablets have a shelf life of 2 years.

Reviews

On the use of Ascoril in the treatment of dry cough in children, mothers leave a lot of positive feedback. According to them, the remedy very effectively dilutes sputum and helps to remove it from the bronchi. The fact that such a medicine helps quickly enough is also evidenced by the opinions of doctors. Many pediatricians note that a course of treatment with Ascoril for 5-7 days is often enough to get rid of a cough.

Parents call the disadvantages of Ascoril syrup quite common side effects(many note headaches, tremors, rapid pulse, weakness and nausea) and the presence of chemical additives in the composition. Also, some children do not like the taste of such a drug, because it is bittersweet.

Analogues

If Ascoril is prescribed to a child, but it is not possible to give this medicine for one reason or another, the question naturally arises of how to replace such a drug. A similar effect is observed in the following drugs:

Cashnol. Such a syrup is a complete analogue of Ascoril in composition and content of active substances. It comes in a red raspberry flavored liquid and is available in 100ml and 200ml bottles. Indications for use and doses of such a drug are exactly the same as those of Ascoril in syrup.

Erespal. This medication, which is based on the antihistamine compound fenspiride, helps eliminate bronchospasm and reduce inflammation. It is prescribed for laryngitis, whooping cough, influenza, sinusitis, asthma and other pathologies. Erespal is represented by syrup (prescribed from 2 years of age) and coated tablets (not used by the age of 18 years). It is permissible to take Erespal and Ascoril at the same time, because such drugs act on different receptors.

In this article you will see detailed instructions for the use of cough syrup - Ascoril. Read how to drink it for children and adults, in what dosage and what indications and contraindications the medicine has.

In the rainy season, colds usually begin, and not only in children, but also in adults. An unpleasant symptom that accompanies almost all ailments is a cough. It is difficult to get rid of it, it can last a week or even two (with the wrong treatment). Means that patients buy in a pharmacy do not bring the proper therapeutic effect, and sometimes vice versa - they harm.

People often choose their own medicines just for coughing, without delving even deeper into the problem. But cough is different, respectively, and dosage forms must be selected taking into account this factor. Next, we will find out in which cases Ascoril is taken, and all the details about this drug.

Ascoril syrup: composition, indications for use

This syrup differs from others in its composition. It has four effective components that together give a good effect for the treatment of cough. These are elements such as:

Bromhexine
Racementhol
Salbutamol
Guaifenesin

Even in Ascoril syrup there are a number of auxiliary elements. Thanks to them, it has a pleasant taste, a bright, slightly specific smell and is stored for a long time. The preparation contains flavors (pineapple, blackcurrant) and dye. Therefore, patients with allergies should pay attention to the components of the syrup in order to protect themselves from all sorts of complications.

Cough syrup - Ascoril

According to the instructions, this syrup is effective for dry cough. In combination with other dosage forms, it is recommended to drink it:

In inflammatory processes that occur in the upper respiratory tract, with bronchitis, lung diseases.
The syrup eliminates cough if the patient has laryngitis, bronchial asthma, emphysema, tuberculosis, silicosis.
Whooping cough is also amenable to treatment with this drug. Its effect is noticeable after the first dose in half an hour for eight hours.
Ascoril facilitates the course of such a disease as pneumoconiosis. This pathology develops most often in enterprises due to the ingress of a large amount of dust into the lungs.
At bronchiectasis Ascoril facilitates expectoration of thick sputum.

Treatment with Ascoril syrup

IMPORTANT: This drug should be taken only on the advice of your doctor. Because the medical worker takes into account all the features of this remedy, and he has many contraindications.

Ascoril syrup - from what age can children be given, with what cough to take: with dry or wet?

If a pediatrician prescribes syrup to a child, then he evaluates the pros and cons. Each small patient manifests individual characteristics of the course of the disease, and the doctor takes this into account. In one baby with bronchitis, sputum is abundantly secreted, in the other, on the contrary, a dry cough appears. In the second case, the appointment will be appropriate, in the first - no. The components of Ascoril have a certain effect on the mechanism of cough action.

Bromhexine - perfectly dilutes sputum
Guaifenesin - also thins phlegm, relaxes the muscle tissue of the bronchi
Salbutamol - promotes the expansion of bronchial tissues
Racementhol - has an antiseptic, soothing effect.

Ascoril - for children

The syrup gives a positive effect in the treatment of dry cough. That is why a specialist doctor may recommend taking it to a child up to a year old. The dose of the drug is selected individually.

If the baby has laryngitis, then you can not immediately begin treatment with such a syrup. First, you need to remove the inflammation so that the pain disappears, there are no problems when inhaling, exhaling. Because during the period of inflammation, the larynx narrows. And thanks to Ascoril, sputum will begin to come out abundantly, the larynx will not be easy to cope with the increased secretion of mucus.

At what age do children give Ascoril syrup?

With the manifestation of bronchial asthma, the treatment mechanism is also carried out in a certain sequence. You can not immediately start taking this drug, there is a risk of aggravating the condition of a sick child.

IMPORTANT: A pediatrician determines the improvement of the health picture with the help of diagnostics, x-rays. Only with the help of these measures is it established when and which drugs to prescribe.

Ascoril syrup: instructions for use and dosage for children up to a year and older than a year

When children get sick, adults always worry and want their beloved baby to get better as soon as possible. They do not spare any money even for the most expensive pharmacy products. But do not immediately buy all the drugs that are advertised by pharmaceutical companies, they can be completely useless. So the syrup is completely useless with a wet cough. Ascoril perfectly fights thick sputum, stimulates its withdrawal.

The medicine is not recommended for babies under one year old. And starting from one year to six, syrup is consumed in a dose - five milliliters (three times a day). The course of treatment can last from five to seven days. So it is written in the instructions for the drug.

Dosage of Ascoril - for the treatment of cough in children

However, the pediatrician can independently calculate the dosage for the child. Sometimes his recommendations differ from generally accepted norms. Much depends on the weight of the baby, his state of health. You can take the syrup only twice a day, or you can take it three times.

Starting from the age of six, Ascoril syrup is taken three times a day, five to ten milliliters. It depends on the severity of the cold infection. Still, it is better to drink the drug after eating and drink a small amount of water.

Ascoril syrup: instructions for use and dosage for adults

For adults, syrup is prescribed by a pulmonologist. This dosage form is not used to treat common infections. As mentioned earlier, it works productively only with a dry cough. Most often, such symptoms are observed with pneumonia, tuberculosis, bronchitis, etc. Such pathologies should be treated in combination with antibacterial drugs.

Treatment of cough in adults with Ascoril

For adults, it is preferable to use Ascoril tablets, but if you prefer syrup, then drink 10 milliliters of syrup — three times a day until complete relief from the unpleasant symptom of the disease. Do not exceed the course of treatment with syrup - 7 days.

IMPORTANT: You can not use the drug for laryngitis in the initial phase of the disease, bronchial asthma, until you remove the symptoms of inflammation of the larynx, bronchi. Ascoril is not the drug that is used completely uncontrollably. He is able to improve the condition of the patient, and vice versa.

How to take Ascoril cough syrup for adults and children: before meals or after meals?

The syrup has an irritating effect on the walls of the stomach, which is why it should be drunk only after eating. It is advisable to do this no later than an hour after eating. Drink the dosage form with plain purified water. Do not use soda drink with it (dairy products, mineral water with a high content of bicarbonates). Thus - you will reduce the effect of the syrup. Or it will be completely useless.

Ascoril - for coughing in adults

Ascoril syrup: how many days should adults and children take?

According to the description, Ascoril is applied for one week. If during this time the drug has not affected the course of the disease, then it should be canceled and contact the doctor again. Long-term treatment with this remedy is not provided, undesirable complications may develop.

What is the period of treatment with Ascoril?

What can replace Ascoril syrup for a child?

The syrup has a unique composition, so it is quite difficult to replace it. You can find other drugs in the pharmacies of the city, with completely different components. They have a similar effect on the child's body in the treatment of dry cough. These include:

Ambroxol
Lorkoff
Pertussin
Bromhexine
Bronchicum
Lazolvan
Liquorice root
Alteyka

Ascoril syrup analogues for children

Ascoril syrup: contraindications, side effects

Whenever you take a drug for treatment, be sure to read the instructions. It is especially important to know the contraindications and side effects of the drug. Ascoril syrup has the following contraindications:

You can not use the medicine for patients with hypertension and patients with pathologies of the cardiovascular system.
Refrain from taking the remedy if you have hormonal diseases (diabetes, hyperthyroidism, thyrotoxicosis).
In diseases of the gastrointestinal tract, the drug is contraindicated.
Do not recommend taking syrup for children under one year old.
You can not use Ascoril together with cough blockers.
Allergy to any component of the syrup also reduces the intake of syrup to nothing.

As a result of treatment with this syrup, various side processes may occur. If they occur, then cancel the drug as a matter of urgency.

Side effects:

Palpitations, trembling, agitation
Collapse, cramp in limbs
Urine color change
Rash, spots on the skin
Migraine, sleep disturbance
Problems with the gastrointestinal tract, bleeding
Bronchospasm

Ascoril syrup: reviews of doctors and adults

After studying the reviews about this drug, we can conclude that the syrup is quite an effective cough remedy, but the presence of dyes and other components cause allergies in many patients.

Lilia, 34 years old

In autumn, in kindergarten, the child caught a cold. The cough was dry and strong. The doctor prescribed Ascoril 5 ml three times a day. The result showed up very quickly. In the evening, the cough subsided. The only bad thing is that the drug has many contraindications, so it must be used carefully.

Vladimir, 29 years old

The drug is prescribed only for certain types of pathology. You need to know that not every dry cough can be treated with it. For example, with laryngitis, the drug is not effective. Therefore, do not make appointments for yourself, come to the clinic for a consultation so as not to harm your health.

Do not rush to immediately use strong drugs on your own at the first sign of a cold. Do not prescribe them yourself, let an experienced doctor advise you about the treatment. Perhaps the simplest treatment options will suffice. Such as - rubbing, washing out bacteria with ordinary warm drinks, the use of herbal preparations.

Video: Ascoril syrup - how to apply?

In almost any first aid kit there is a cough remedy that affects both children and adults. Many drugs are allowed to be taken only by adults, for children you have to purchase special medications separately. Our article will tell you about such a drug as Ascoril, its significant advantage is that it is suitable for patients of different ages (except for infants), and you can choose the dosage form that is right for you. We will provide you with information about the composition and pharmacological properties of the drug, as well as tell you how and how many days you can take depending on the age category.

Instructions for the drug Ascoril: pharmaceutical group, indications for use and adverse reactions

Cough occurs due to the narrowing of the airways, as well as due to irritation of the bronchial mucosa, so the medicine should relieve these symptoms well.
The pharmacological group to which Ascoril belongs is expectorant combined drugs.

There are two forms of release of the drug:

Tablets
syrup expectorant

Below we will analyze each of them in more detail.

Both dosage forms contain the same active substances, which differ in dosage in one tablet and in 10 ml of syrup:

bromhexine hydrochloride - 8 mg / 4 mg;
guaifenesin - 100 mg / 100 mg;
salbutamol - 2 mg / 2 mg.

Excipients contained in the syrup: glycerol, sorbitol, sodium benzoate, sucrose, propylene glycol, citric acid, sorbic acid, yellow dye, purified water, pineapple and blackcurrant flavor, menthol in microdoses.

Additional components of the tableted product are hydrophosphate, corn starch, propylparaben, calcium hydrogen phosphate, methylparaben, silicon dioxide, purified talc, magnesium stearate in microdoses.

Pharmacological properties - a combined medication with expectorant, bronchodilator and mucolytic effects.

Pharmacodynamics. Guaifenesin stimulates the bronchial mucosa to secrete, reduces the viscosity of sputum. With a dry cough, it contributes to its transition to a wet one, and facilitates the discharge of sputum. This mucolytic agent weakens the surface tension of the structures in the bronchopulmonary apparatus.

Bromhexine is a mucolytic agent that promotes sputum discharge, exerting an expectorant effect. Reduces cough, stimulates the cilia of the ciliated epithelium, providing a directed movement of sputum. If you take bromhexine for a long time, it can accumulate in the body.

Salbutamol is a powerful bronchodilator component, has a relaxing effect on the smooth muscle tissue of the bronchi, relieves bronchospasm. It also has a stimulating effect on the beta2-adrenergic receptors of the bronchi and blood vessels, expanding the coronary arteries and increasing the patency of the bronchi. Salbutamol also helps to increase the marginal capacity of the lungs, suppresses air resistance in the airways that occurs when they are narrowed.

Pharmacokinetics. Salbutamol is absorbed fairly rapidly when taken orally, but absorption decreases with food intake without decreasing bioavailability. 10% binds to plasma proteins. It penetrates well through the placental barrier.

Metabolized in the liver and intestinal walls. 70-90% is excreted from the body with the help of the kidneys in the form of an inactive phenol sulfate metabolite and 4% with bile in 72 hours. Bioavailability about 50%.

Bromhexine is absorbed from the gastrointestinal tract by 99% within half an hour, the bioavailability is low. It penetrates well through the placental barrier and the BBB. In the liver, it is metabolized to the pharmacologically active ambroxol. It is excreted from the body by the kidneys, however, in chronic kidney failure, the excretion of metabolites is impaired.

Guaifenesin is absorbed from the gastrointestinal tract in 25-30 minutes, absorption is high. Penetrates into tissues that contain mucopolysaccharides. About 60% is metabolized in the liver. It is excreted from the body, both in the form of inactive metabolites, and in an unchanged state by the kidneys or lungs (with a viscous secret).

Indications for use. Ascoril is prescribed for various diseases of the respiratory organs, which are accompanied by a strong cough and bronchial spasms with sputum difficult to separate.

It is used in combination with other drugs for the treatment of such diseases:

Bronchitis, including obstructive, in which a limited amount of air enters the airways;
Tracheobronchitis is an acute inflammatory process in the bronchi and trachea;
Bronchial asthma;
Histologically confirmed and unconfirmed pulmonary tuberculosis;
Emphysema of the lungs - increased air content in the tissues of the lungs;
Cystic fibrosis is a complex disorder of the respiratory organs;
Whooping cough is a severe infection accompanied by a cough with spasms;
Pneumoconiosis - occurs with prolonged inhalation of industrial dust and dirt.

Because Since the active substances transform an unproductive cough into a productive one, the drug is indicated for use in dry cough.

There are some tips for use for patients with pathologies. So, in case of severe diseases of the heart and blood vessels, you should see a doctor, because. collapse may occur.

During pregnancy, Ascoril should not be used. If the medication is prescribed to a nursing mother, lactation must be stopped for a while, it can be resumed 48 hours after the drug is discontinued.

Side effects are quite rare, and unwanted reactions may still occur.

From the side of the central nervous system:

sleep disorder;
tremor;
pain in the head;
convulsions;
increased anxiety;
drowsiness.

From the CCC:

a sharp decrease in blood pressure;
tachycardia.

From the digestive tract:

exacerbation of peptic ulcer;
dyspepsia;
nausea;
diarrhea;
change in blood biochemistry.

Allergic reactions may also occur in the form of itching and rashes on the components of the drug, in particular on the dye contained in the syrup.

Urine may be pink in color, but you should not pay attention to this, because. it has no effect on health.

Contraindicated for pregnant women and children under one year old. Also, do not take patients with diseases such as:

aortic stenosis;
Tachycardia;
Arrhythmia;
Myocarditis;
Heart defects;
thyrotoxicosis;
Violations of the functions of the kidneys and liver;
Ulcers of the stomach and duodenum;
Increased intraocular pressure.

Under the supervision of a physician, take patients suffering from diabetes.
Interaction with other drugs should also be taken into account when prescribing.

Diuretic drugs such as Diacarb, Lasix, Veroshpiron, Furosemide, and glucocorticosteroids (Nasonex, Kenalog, Solumedrol, Prednisolone, Flixonase) enhance the effect of salbutamol, resulting in a decrease in potassium in the blood.
It is forbidden to take it simultaneously with monoamine oxidase inhibitors (Pirlindol, Iproniazid, etc.)

At the same time, Ascoril should not be taken with codeine-containing drugs and other cough medicines, because. this makes it difficult to separate the liquefied secret.

Medicines from the same pharmaceutical group with salbutamol (Berodual, Serevent, Ventolin, etc.), as well as the bronchodilator Theophylline, enhance its effect.

When taken with antibiotics (Erythromycin, Macropen, Cefazolin), Bromhexine helps their penetration into the lung tissue.

Keep out of the reach of children and animals, well ventilated and protected from the sun, at a temperature not exceeding 25 degrees.

Tablets Ascoril - how to take it correctly?

One package of Ascoril may contain 10 or 20 white flat tablets with a dividing strip in the middle.

Despite the fact that the drug is intended for both adults and children, young patients under six years of age should still prefer syrup to tablets.

It is best to take the tablets 30 minutes or an hour after eating. You need to drink clean drinking water. The use of mineral water with a high content of bicarbonate, as well as a mixture of milk and soda, is prohibited for washing down. alkaline drinking significantly reduces the therapeutic effectiveness of the drug.

Children from six to twelve years of age should take Ascoril for cough, dividing the tablet in half. One half - once a day.

Children over 12 years old, as well as adult patients, can take the drug in equal doses - one whole tablet three times a day.

The duration of taking the tablet preparation is prescribed individually by the attending physician.

Ascoril syrup - application features

It is recommended to shake the expectorant syrup before use. This form of Ascoril is perfect both for the treatment of adults and for young children from a year old. However, without the necessary indications, pediatricians do not prescribe this drug, and on their own initiative, it is impossible to give a syrup to a child at all, just as it is impossible for an adult to take it on their own.

Frequent indications for the appointment of children is a violation of sleep and breathing due to a strong cough. Because medicine in liquid form is easier to swallow, syrup is the best solution to the problem. The same applies to elderly patients.

The term "expectorant" means that the medicine is intended to thin the secreted viscous secretion, as well as to facilitate expectoration of sputum, that is, it will not work with a wet cough.

Ascoril syrup is a clear yellow liquid with a pleasant taste and currant aroma. Therefore, babies are easily persuaded to take a spoonful or two of the drug.

The dosage depending on the age of the patients is as follows:

children under six years of age are prescribed three doses of 1 teaspoon (5 ml) per day;
children from six to twelve years old - 1-2 teaspoons (5-10 ml) three times a day;
children over 12 years of age and adult patients should take no more than 2 teaspoons (10 ml) three times a day.

It should be taken orally with water if desired.

The drug in the form of a syrup is available in dark-colored plastic bottles; a measuring cap is attached to it. Vials can be 100 or 200 ml packed in cardboard boxes.

If you forget to take a medicine, it should be done as soon as you remember. But if the next dose is close, it is better to skip the forgotten spoon in order to avoid an overdose.

The use of the medicine by children should not exceed seven days, for adults, if necessary, the period of treatment can be extended by the doctor.

The price of Ascoril and available analogues of this medicine

The price of the drug is quite high, so many patients ask to be prescribed some kind of medicine that can replace an expensive drug with a more affordable one, but with the same medicinal properties.

The drug is produced by the Indian pharmaceutical company Glenmark Pharmaceuticals. Completely identical in composition analogues of Ascoril do not yet exist, however, there are many drugs on the shelves of pharmacies, which include its individual components. Bromhexine can be attributed to such an analogue, it is included in the category of the cheapest cough medicines.

The following means can also serve as a replacement for Ascoril:

Erespal
Acetylcysteine
Lazolvan
Alteyka
Pectolvan C
Ambroxol
Pertussin
Codelac broncho, etc.

There are many analogues of the drug, but without consulting with the attending physician, it is impossible to replace the prescribed medicine. Especially after reading forums with user advice. This is due to the fact that this or that drug may be perfect for one person, but completely not suitable for another, that is, you.

Ascoril is released only upon presentation of a prescription, and it is forbidden to give it to third parties.