Almagel yellow instructions for use. Almagel, instructions for use for proper use. Which is better - Almagel or Almagel NEO

Instructions for use Almagel Neo recommends taking it to patients with diseases gastrointestinal tract. Taking the drug is especially important for people suffering from symptoms of flatulence after eating. Almagel Neo quickly eliminates increased gas formation, a feeling of fullness, sour belching and painful heartburn. Thanks to the combined multicomponent composition medicine has an antacid and laxative effect. Almagel Neo is a pharmacological drug that has contraindications, so before taking the suspension you should make an appointment with a gastroenterologist. The doctor will determine single and daily dosages, as well as the duration of the therapeutic course.

Almagel Neo will help reduce acidity gastric juice and eliminate dyspeptic disorders

Therapeutic effect of the drug

Almagel Neo contains several active ingredients that determine its therapeutic properties and scope of application. Aluminum hydroxide reacts with neutralization with caustic gastric juice, reducing its acidity. U chemical compound There is a drawback - it provokes constipation. Mitigating actions help to avoid the development of events in such a negative scenario:

magnesium hydroxide;
sorbitol.

Almagel Neo differs from its predecessor green Almagel in its bright orange packaging and the presence of simethicone. This substance is capable of changing the surface tension of gas bubbles forming in the gastrointestinal tract. The result is their collapse and absorption by the mucous membranes. Thus, after taking Almagel Neo, the multifaceted therapeutic activity of the drug manifests itself:

antacid;
laxative;
carminative.

After penetration into the stomach, Almagel Neo promotes the formation of a protective film on the mucous membrane. It prevents the effects of pepsin and hydrochloric acid on ulcerative lesions. Simethicone exhibits adsorbent properties, absorbing toxic compounds on its surface and then removing them from the body.

Almagel Neo in bags is convenient to take with you to work and travel

Instructions for use

Manufacturers produce Almagel Neo in the form of a white suspension with an orange smell and a sweetish taste. Antacid packaged in 170 ml dark glass bottles. When the drug is rarely used, solid particles of the suspension settle to the bottom. This does not mean that Almagel Neo is unsuitable for use - just shake the bottle.

Recommendation: “A new product has appeared on pharmacy shelves. dosage form- Almagel Neo in 10 ml sachets with a tear-off corner. This medicine is convenient to take with you on business trips, travel, to the place of duty and special events.”

Almagel Neo is most often used for course use in therapy:

dyspeptic disorders;
ulcerative lesions;
hyperacid gastritis.

Unlike other types from the therapeutic line, this antacid is taken an hour after a meal. This feature is based on the properties of simethicone, which collapses gas bubbles. Almagel Neo should not be taken with water, as the concentration of active ingredients and therapeutic effectiveness will decrease. Presence in the composition of the drug large number ingredients involves not only it wide range application, but also increases the number of contraindications. A gastroenterologist will tell you how to take Almagel Neo. He will create an adequate therapeutic regimen that minimizes the likelihood of side effects.

Indications for use

Simethicone belongs to a group of organosilicon compounds that exhibit defoaming properties. This determines the carminative activity of Almagel Neo, for which the suspension is used in the treatment of fermentative and putrefactive dyspepsia. These pathological processes develop when food stagnates in the stomach for a long time due to gastrointestinal motility disorders.

Advice: “Bloating, seething and rumbling often occurs in people with a sweet tooth and people who eat a monotonous diet. Gastroenterologists recommend taking Almagel Neo in such cases, but not more than 2-3 times a week.”

The drug is prescribed to patients as part of complex therapy when they are diagnosed with the following pathologies:

gastritis in chronic form occurring against the background of excessive or normal production of hydrochloric acid;
reflux esophagitis;
acute form of gastritis, duodenitis, peptic ulcer stomach and duodenum;
ulcerative lesions digestive tract any etiology;
gastroesophageal reflux;
increased gas formation.

Almagel Neo is used to prevent ulcerations of the mucous membranes of the gastrointestinal tract that develop when taking pharmacological drugs. An antacid is also used to relieve heartburn that occurs after drinking alcohol, strong tea or coffee.

Almagel Neo should be taken only after examination and as prescribed by a gastroenterologist

Pancreatitis

This disease is characterized by a decrease in the production of enzymes by the pancreas. As a result, the food bolus takes a long time to move through the gastrointestinal tract, and difficulties arise with its digestion. A person experiences not only symptoms of flatulence, but also pain in the epigastric region. A course of taking Almagel Neo or Almagel A for pancreatitis helps to quickly and effectively get rid of sour belching, heartburn, a feeling of fullness, attacks of nausea and vomiting.

Diarrhea

With diarrhea, a lot of fluid and microelements necessary for the functioning of all vital systems are removed from the human body. Diarrhea always develops when intestinal infections viral and bacterial origin. Disorder of peristalsis often accompanies flatulence, significantly worsening a person’s condition. Despite some laxative properties, Almagel is prescribed to many patients of gastroenterologists for diarrhea. Even a single use of the drug reduces the severity of symptoms of flatulence and normalizes the motility of the digestive tract.

Overdose

nausea, vomiting;
chronic constipation or diarrhea;
fatigue, weakness.

Such symptoms often occur in people who self-medicate and take antacids without a medical prescription. This is especially dangerous if there is one of the drug’s contraindications:

children under 10 years of age;
pregnancy and lactation;
Alzheimer's disease;
severe pathologies of the urinary system and liver.

Long-term use of Almagel Neo in high doses conditions provokes the development of hypermagnesemia. The pathology is characterized by muscle weakness, facial redness, and weight loss. An overdose of Almagel is expressed in emotional instability, distortion of taste sensations, and slowing of the respiratory rhythm.

Warning: "If clinical picture overdose, you should stop taking Almagel Neo. Gastroenterologists recommend taking any enterosorbent and seeking medical help.”

Active ingredients:
	5 ml (1 measuring spoon) of suspension contains:	10 ml (1 sachet) of suspension contains:
aluminum hydroxide gel in terms of aluminum hydroxide
magnesium hydroxide paste in terms of magnesium hydroxide
emulsion of simethicone 30% in terms of polydimethylsiloxane
excipients: hydrogen peroxide solution (30%), sorbitol (E 420), sodium saccharin, hydroxyethylcellulose, citric acid monohydrate, ethyl parahydroxybenzoate (E 214), propyl parahydroxybenzoate (E 216), propylene glycol, macrogol 4000, orange flavor, ethanol 96%, purified water.

Dosage form

Suspension for oral administration.

Basic physical and chemical properties: suspension of white or almost white with the scent of orange.

Pharmacological group

Antacids. Combinations simple salts and carminatives (antiflatulents). ATX code A02A F02.

Pharmacological properties

Almagel ® Neo is a balanced combination of aluminum hydroxide and magnesium hydroxide with a carminative component - simethicone. It has a long-term antacid effect, has a mild laxative effect, successfully eliminates constipation and reduces flatulence in patients with stomach ulcers.

Its dual mechanism of action, combining acid-neutralizing abilities and cytoprotective activity, ensures the protection of the gastric mucosa and its healing when damaged.

The alkaline active components of the drug are finely dispersed, which increases their active surface, ensures closer contact with the surface of the mucous membrane of the stomach and duodenum, slows down the evacuation of stomach contents and prolongs the neutralizing effect.

Cytoprotective activity is associated with activation of the synthesis of prostaglandins, which stimulate the secretion of mucus and bicarbonates from the gastric mucosa.

Considering the ability of the drug to bind bile acids and lysolecithin, as well as to have a gastroprotective effect, Almagel ® Neo can be used for the treatment of duodenogastric reflux.

Simethicone, which is part of the drug, helps eliminate flatulence.

Simethicone is a stable silicone compound, is not absorbed from the digestive tract, causes the natural release of gases and their absorption by the intestinal walls.

Simethicone exerts its effect in the lumen small intestine and is excreted from the body unchanged.

The components of the drug are not absorbed from the gastrointestinal tract and, thus, do not lead to clinically significant plasma concentrations when used in recommended doses and for the recommended duration of treatment.

Aluminum hydroxide neutralizes the increased secretion of hydrochloric acid in the stomach, forming aluminum chloride. Under the influence of the alkaline environment of the intestine, the latter turns into alkaline aluminum salts, which are poorly absorbed and excreted in feces. With normal kidney function serum level aluminum remains virtually unchanged.

Magnesium hydroxide also neutralizes hydrochloric acid in the stomach and turns into magnesium chloride. In the intestine, it turns into magnesium carbonate, which is poorly absorbed, so the concentration of magnesium ions in the blood remains virtually unchanged.

In patients with chronic renal failure, the level of aluminum and magnesium ions may increase to toxic levels due to impaired excretion.

Indications

Symptomatic treatment of diseases of the digestive tract, which are accompanied by increased or normal acidity of gastric juice and increased gas formation.

The drug should be used alone or in combination with other drugs for:

gastritis and duodenitis;
stomach and duodenal ulcers;
erosion of the stomach and duodenum;
gastroesophageal reflux disease;
duodenogastric reflux;
functional dyspepsia;
flatulence, discomfort as a result of increased gas formation.

Contraindications

Hypersensitivity to aluminum hydroxide, magnesium hydroxide or simethicone and/or excipients that are part of the drug. Severe renal impairment, including in patients on hemodialysis, in whom there is a risk of increasing the concentration of aluminum and magnesium ions in the blood serum to toxic levels as a result of decreased renal excretion. Hypophosphatemia, severe osteoporosis, habitual constipation, chronic diarrhea, intestinal obstruction, suspected appendicitis, bleeding from the digestive tract of unknown origin, severe abdominal pain of unspecified origin, ulcerative colitis, states, causing disturbance water and electrolyte balance.

Interaction with other drugs and other types of interactions

Almagel ® Neo interacts with some other drugs used orally. There is a decrease in the volume of absorption from the gastrointestinal tract of drugs taken simultaneously. As a precaution, you should wait at least 2 hours between taking antacids and other medications.

Simultaneous use with the drug Almagel ® Neo can lead to a decrease in the absorption of the following drugs: tetracycline antibiotics (for example, tetracycline, doxycycline); quinolones (eg, ciprofloxacin, norfloxacin, ofloxacin); bisphosphonate derivatives (eg cloronate, alendronate, risedronate); protease inhibitors (atazanavir, tipranavir, fosamprenavir); ketoconazole, itraconazole; rosuvastatin; allopurinol, diflunisal, gabapentin, iron, mycophenolate mofetil; levothyroxine; dasatinib; Strontium ranelate.

Plasma concentrations of penicillamine, sotalol, propranolol, phenytoin, cefpodoxime, fexofenadine may decrease when used simultaneously with antacids. The effect of calcium polystyrene sulfonate may be reduced if used concomitantly. antacids. You should also observe a two-hour interval between doses with the following medications: H2 - antihistamines, antituberculosis drugs: ethambutol, isoniazid (oral), atenolol, metoprolol, chloroquine, cyclines, digoxin, sodium fluoride, glucocorticoid drugs (interaction with prednisolone and dexamethasone is described ), indomethacin, lansoprazole, lincosamides, phenothiazine antipsychotics, phosphorus (supplements).

Combinations to consider.

When used simultaneously with salicylates, the excretion of salicylates by the kidneys is enhanced due to alkalinization of the urine.

The drug should not be used simultaneously with quinoline.

The elimination of quinidine may be impaired with manifestations of quinidine toxicity, especially in patients with renal failure.

Concomitant use with cholinergic drugs reduces their effectiveness.

Concomitant use of aluminum hydroxide and citrates may result in increased aluminum levels, especially in patients with renal impairment.

The use of the drug with drugs that have an enteric coating, which can lead to faster dissolution of the coating and irritation of the stomach and duodenum.

The drug may reduce absorption folic acid.

Pirenzepine enhances and prolongs the effect of Almagel ® Neo.

Probability drug interactions less when using antacid drugs in low doses.

Application Features

Before starting to use the drug, the presence of a malignant process should be excluded.

Aluminum hydroxide can lead to constipation and magnesium hydroxide can cause intestinal hypokinesia. Use of this drug in high doses may cause or worsen intestinal obstruction and intestinal obstruction, especially in patients at increased risk of such complications, such as patients with renal failure or elderly patients.

Patients should consult a doctor if:

reducing body weight;
having difficulty swallowing or constant feeling abdominal discomfort;
digestive disorders that appeared for the first time, or a change in the course of existing digestive disorders;
renal failure.

In patients with impaired renal function, plasma levels of aluminum and/or magnesium may increase, so it should be taken into account that long-term use of high doses of the drug can lead to the development of dementia and microcytic anemia.

With long-term use of the drug, it is necessary to ensure that a sufficient amount of phosphorus enters the body, since aluminum hydroxide binds to phosphates and reduces their absorption from the digestive canal. In addition, the excretion of calcium in the urine increases, which can lead to disturbances in the calcium-phosphate balance and create conditions for the development of osteomalacia (symptoms - complaints of weakness and pain in the bones). This medicine is not suitable for patients suffering from hypophosphatemia as it may cause hypophosphatemia with long-term use.

This drug should be used with caution in patients with renal impairment. When treating patients with renal failure, it is necessary to monitor over time indicators of the condition of the kidneys, the size of the ulcer, the appearance of diarrhea, and the serum level of aluminum and magnesium.

Children. The use of magnesium hydroxide in young children may lead to hypermagnesemia, especially in cases of renal failure or dehydration.

One dose (10 ml) of the drug contains:

0.226 g of ethanol, the presence of which may negatively affect the condition of patients with liver and brain diseases, persons with alcohol addiction, epilepsy, pregnant women and children under 14 years of age;
0.95 g sorbitol, which is contraindicated in patients with rare hereditary diseases such as fructose intolerance, and may cause stomach irritation and diarrhea.

Parabens, which are included in the drug as excipients, may cause allergic reactions, including urticaria, bronchospasm.

Use during pregnancy or breastfeeding

Due to the lack of adequate data clinical trials Almagel ® Neo can be used by women during pregnancy only as prescribed by a doctor if the expected benefit for the mother exceeds possible risk for the fetus/child.

The content of aluminum and magnesium ions that can affect transit in the gastrointestinal tract should be taken into account, namely:

– magnesium hydroxide salts can cause diarrhea;

– aluminum salts can cause constipation and worsen constipation, which is often observed during pregnancy,

Therefore, long-term use and excessive doses of this drug should be avoided.

When Almagel ® Neo is used by pregnant women, the drug may cause harm due to the ethyl alcohol content (0.226 g in one dose).

Due to the lack of data from adequate clinical studies, Almagel ® Neo can be used by women during breastfeeding only as prescribed by a doctor if the expected benefit to the mother outweighs the possible risk to the child.

The ability to influence the reaction rate when driving vehicles or other mechanisms

No data available regarding negative influence on the ability to manage vehicles or work with complex mechanisms.

Directions for use and doses

Adults and children over 14 years old

For gastroesophageal reflux disease, the recommended dose is 10-15 ml (2-3 scoops) or 1 sachet 4 times a day, 1 hour after meals and before bedtime. After achieving the desired effect, the recommended dose is 10 ml (2 scoops) or 1 sachet 4 times a day.

For gastritis, duodenitis, erosion of the stomach and duodenum, peptic ulcer of the stomach and duodenum, duodenogastric reflux, functional dyspepsia, flatulence, the recommended dose is 10 ml (2 scoops) or 1 sachet 4 times a day 1 hour after meals and before sleep.

The duration of treatment is determined by the doctor.

Maximum daily dose- 60 ml (12 measuring spoons or 6 sachets), maximum duration treatment - 4 weeks.

If symptoms do not go away, you should consult a doctor.

The drug should be taken undiluted. It is not recommended to drink liquids within 30 minutes after administration. Before use, the suspension must be thoroughly homogenized by shaking the bottle.

Patients with impaired renal function. The medicine should be taken after consultation with a doctor. With long-term use, the state of renal function should be taken into account.

Children

For use in children over 14 years of age.

The safety and effectiveness of the drug in children under 14 years of age have not been established.

Overdose

Long-term use of Almagel ® Neo can lead to hypermagnesemia, despite the fact that the drug is almost not absorbed from the digestive tract. Symptoms of overdose include fatigue, facial flushing, exhaustion, muscle weakness and inappropriate behavior.

Signs of metabolic alkalosis may also be observed: changes in mood or mental activity, numbness or muscle pain, nervousness and fast fatiguability, slow breathing, unpleasant taste sensations.

If an overdose of the drug is suspected or if clinical signs it is necessary to discontinue the drug and take measures to rapid removal drug from the gastrointestinal tract (introduce Activated carbon, do gastric lavage and other procedures to reduce the absorption of aluminum and magnesium ions).

Treatment for magnesium overdose: rehydration, forced diuresis. Calcium gluconate can be prescribed intravenously. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.

Side effects

Long-term use of Almagel ® Neo or taking high doses can cause phosphorus deficiency syndrome (loss of appetite, muscle weakness, weight loss).

It should be borne in mind that even when using usual doses drug in patients whose diet is characterized low content phosphorus, it is possible to reduce the phosphorus content in the body, enhance resorption processes in bone tissue, hypercalciuria, osteomalacia, osteoporosis, since this drug contains aluminum (see section “Peculiarities of use”).

Increased plasma concentrations of both aluminum and magnesium have been observed in patients with renal failure, so long-term use of high doses of aluminum and magnesium salts may lead to the development of encephalopathy, dementia, microcytic anemia, or worsen the course of dialysis-induced osteomalacia. Patients with renal failure should receive a reduced dose of the drug or increase the interval between doses of the drug, based on the severity of renal failure. Patients in this group should monitor plasma concentrations of aluminum and magnesium.

Aluminum hydroxide may be dangerous for patients with porphyria who are receiving hemodialysis.

By frequency adverse reactions classified into the following categories: very common (≥ 1/10); often (≥ 1/100,<1/10); нечасто (≥ 1/1000, <1/100) редко (≥ 1/10000, <1/1000); очень редко (<1/10000); частота неизвестна (невозможно оценить по имеющимся данным).

From the immune system. Not known: allergic reactions, including bronchospasm, itching, urticaria, angioedema and anaphylactic reactions.

From the side of metabolism and nutrition. Very rare: hypermagnesemia (observed after long-term use of magnesium hydroxide in patients with renal failure).

From the nervous system. Rare: aluminum and/or magnesium intoxication, mainly in patients with renal failure. Very rare: dementia, worsening of Alzheimer's disease.

From the gastrointestinal tract. Uncommon: taste disturbance (chalk taste). Very rare: diarrhea. Frequency unknown: constipation, abdominal pain.

Best before date

Storage conditions

Store in original packaging at a temperature not exceeding 25 °C. Keep out of the reach of children. Do not freeze!

After the first opening of the primary packaging, the suspension can be stored for 30 days under the specified conditions.

Package

170 ml or 200 ml in a bottle along with a measuring spoon; 1 bottle along with a measuring spoon in a cardboard box.

10 ml in foil bags. 10 or 20 sachets in a cardboard box.

In this article you can read the instructions for use of the drug Almagel. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Almagel in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Almagel analogues in the presence of existing structural analogues. Use for the treatment of heartburn and other symptoms of ulcers, gastritis in adults, children, as well as during pregnancy and breastfeeding. Composition of the drug.

Almagel- neutralizes free hydrochloric acid in the stomach, which leads to a decrease in the digestive activity of gastric juice. Does not cause secondary hypersecretion of gastric juice. It has an adsorbing and enveloping effect, reduces the effect of damaging factors on the mucous membrane.

The therapeutic effect after taking the drug occurs within 3-5 minutes and lasts an average of 70 minutes.

Almagel provides long-term local neutralization of continuously secreted gastric juice and reduces the content of hydrochloric acid in it to optimal limits for treatment. Aluminum hydroxide suppresses the secretion of pepsin, neutralizes hydrochloric acid, forming aluminum chloride, which in the alkaline environment of the intestine turns into alkaline aluminum salts. Magnesium hydroxide also neutralizes hydrochloric acid, turning into magnesium chloride. This counteracts the constipating effects of aluminum hydroxide. Magnesium hydroxide and magnesium chloride are resorbed to an insignificant extent and have virtually no effect on the concentration of magnesium ions in the blood. Sorbitol, which is part of the drug, promotes increased secretion of bile and exhibits a mild laxative effect, complementing the action of magnesium hydroxide.

Almagel does not sharply increase the pH of the stomach contents; it buffers its value from 4.0-4.5 to 3.5-3.8 (physiological value) in the period between doses. The drug forms a protective layer, ensuring uniform distribution of active substances on the gastric mucosa and has a long-lasting local effect without the subsequent formation of carbon dioxide in the stomach, which, in turn, causes flatulence, a feeling of heaviness in the epigastric region and a secondary increase in the secretion of hydrochloric acid.

The drug, when administered orally, is a mildly toxic drug and does not have embryotoxic, teratogenic or mutagenic effects. In some cases, increased tendon reflexes were noted in newborns whose mothers took the drug for a long time. In addition, in newborns there is a risk of developing hypermagnesemia, especially in a state of dehydration, therefore long-term use of the drug for pregnant women and newborns is not recommended.

Benzocaine (part of the drug Almagel A) has an effective and long-lasting local analgesic effect in severe pain.

Simethicone (part of the drug Almagel Neo) impedes the formation of gas bubbles and promotes their destruction. The gases released during this process are absorbed by the intestinal walls and removed from the body through peristalsis.

Compound

Algeldrate (aluminum hydroxide gel) + Magnesium hydroxide paste + excipients (Almagel in green packaging).

Algeldrat (aluminum hydroxide gel) + Magnesium hydroxide paste + Benzocaine + excipients (Almagel A in yellow packaging).

Algeldrate (aluminum hydroxide) + Magnesium hydroxide + Simethicone + excipients (Almagel Neo).

Pharmacokinetics

Almagel is a non-absorbable drug. If the correct dosage regimen and duration of treatment are observed, it is practically not resorbed in the gastrointestinal tract and has a long-lasting, uniform effect without disturbing the electrolyte balance and without creating the risk of alkalosis or other metabolic disorders. It does not irritate the urinary system and, with long-term use, does not cause alkalosis and the formation of stones in the urinary tract.

Indications

peptic ulcer of the stomach and duodenum in the acute phase;
acute gastritis and chronic gastritis with increased and normal secretory function in the acute phase;
duodenitis;
enteritis;
hiatal hernia;
reflux esophagitis;
functional bowel disorders;
colitis;
discomfort and pain in the epigastrium due to errors in diet, after drinking coffee, nicotine, alcohol;
gastralgia, heartburn (after excessive consumption of ethanol (alcohol), nicotine, coffee, taking medications; incorrect diet that negatively affects the functioning of the gastrointestinal tract);
flatulence;
fermentative or putrefactive dyspepsia.

Release forms

Suspension for oral administration.

There are no other forms, be it syrup or tablets.

Instructions for use and dosage regimen

Almagel

The drug is taken orally. Before each dose, the suspension must be thoroughly homogenized by shaking the bottle.

Treatment

The drug is taken 45-60 minutes after meals and in the evening before bedtime.

Adults and children over 15 years of age are prescribed 5-10 ml (1-2 scoops) 3-4 times a day. If necessary, the single dose can be increased to 15 ml (3 scoops). Children aged 10 to 15 years are prescribed at a dose equal to half the dose for adults.

After achieving a therapeutic effect, the daily dose is reduced to 5 ml (1 scoop) 3-4 times a day for 15-20 days.

Prevention

5-15 ml 15 minutes before taking medications with irritating effects.

Almagel A

Inside. As prescribed by the doctor, 1-3 dosage (teaspoons) depending on the severity of the case, 3-4 times a day half an hour before meals and in the evening before bed.

In children, the drug is used strictly as prescribed by a doctor: children under 10 years of age are prescribed 1/3 of the dose for adults, and children from 10 to 15 years of age are prescribed 1/2 of the dose for adults.

For diseases accompanied by nausea, vomiting and abdominal pain, treatment begins with Almagel A, and after the disappearance of the listed symptoms, they switch to taking Almagel.

Almagel Neo

Adults

Orally, 2 scoops of orange-flavored suspension 4 times a day, 1 hour after meals and in the evening before bed. If necessary, the single dose can be increased to 4 scoops, but the maximum daily dose should not exceed 12 scoops.

Children over 10 years old

The dosage is determined by the attending physician - usually 1/2 dose for adults.

The course of treatment is no more than 4 weeks. Before administration, the suspension must be homogenized by shaking the bottle. It is advisable to take Almagel Neo undiluted. It is not recommended to take liquids within half an hour after taking the drug.

Side effect

change in taste sensations;
nausea, vomiting;
stomach spasm;
pain in the epigastric region;
constipation;
drowsiness.

Contraindications

hypersensitivity to the components of the drug;
severe renal dysfunction;
Alzheimer's disease;
early childhood (up to 1 month), up to 10 years (for Almagel Neo).

Use during pregnancy and breastfeeding

Avoid administration to nursing mothers.

Use in children

Contraindication: early childhood (up to 1 month) and up to 10 years with Almagel Neo.

In older children, the drug is used strictly as prescribed by a doctor: children under 10 years of age are prescribed 1/3 of the adult dose, and children from 10 to 15 years of age are prescribed 1/2 of the adult dose.

special instructions

The interval between taking Almagel and other medications should be 1-2 hours.

Long-term treatment with high doses of the drug and phosphorus-poor food can lead in predisposed patients to the development of phosphorus deficiency in the body, increased resorption and excretion of calcium in the urine and the occurrence of osteomalacia. Therefore, when taking the drug for a long time, you should ensure a sufficient intake of phosphorus from food. In patients with chronic kidney failure, in addition to osteomalacia, swelling of the extremities, dementia and hypermagnesemia may be observed.

The bottle should be shaken before use.

Drug interactions

With simultaneous use, Almagel can reduce the therapeutic effect of tetracycline antibiotics, histamine H2 receptor blockers, digitalis glycosides, iron salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indomethacin and ketoconazole.

Analogues of the drug Almagel

Structural analogues of the active substance:

Ajiflux;
Almol;
Alumag;
Almagel A;
Almagel Neo;
Anacid forte;
Gastracid;
Maalox;
Maalox mini;
Rivolox.

Analogs by pharmacological group (antacids):

Additive calcium;
Aktal;
Alfogel;
Alugastrin;
Anacid forte;
Antareit;
Becarbon;
Gastal;
Gasterin;
Gastrik;
Gastroromazole;
Gaviscon;
Gaviscon forte;
Gelusil;
Gelusil varnish;
Gelusil;
Gestid;
Daijin;
Calcium carbonate;
Magalfil 800;
Magnatol;
Magnistad;
Magnesium oxide;
Milk of Magnesia;
Sodium bicarbonate;
Sodium bicarbonate;
Relzer;
Rennie;
RioFast;
Rokzhel;
Rutacid;
Simalgel VM;
Scoralite;
Talcid;
Tams;
Tannacomp;
Tisacid;
Topalkan;
Phosphalugel;
Andrews antacid.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Trade name of the drug

Almagel ® Neo

International nonproprietary or generic name

Algeldrate + Magnesium hydroxide + Simethicone

Dosage form

Oral suspension

Aomagel ® Neo Composition

5 ml (one scoop) of suspension contains:
Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 340 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 395 mg;
Simethicone (simethicone emulsion - in terms of dimethicone) 36 mg;

hydrogen peroxide solution 30% 0.495 mg, sorbitol 474.60 mg, sodium saccharinate 1.13 mg, hyaetellose 5.65 mg, citric acid monohydrate 5.65 mg, ethyl parahydroxybenzoate 7.90 mg, propyl parahydroxybenzoate 3.40 mg, propylene glycol 113, 00 mg, macrogol 4000 452.00 mg, orange flavor 2.26 mg, ethanol 96% 113.00 mg, purified water up to 5 ml.
10 ml (1 sachet) of suspension contains:
Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 680 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 790 mg;
Simethicone (simethicone emulsion - in terms of dimethicone) 72 mg;

hydrogen peroxide solution 30% 0.990 mg, sorbitol 949.20 mg, sodium saccharinate 2.26 mg, hyaetellose 11.30 mg, citric acid monohydrate 11.30 mg, ethyl parahydroxybenzoate 15.80 mg, propyl parahydroxybenzoate 6.80 mg, propylene glycol 226, 00 mg, macrogol 4000 904.00 mg, orange flavor 4.52 mg, ethanol 96% 226.00 mg, purified water up to 10 ml.

Aomagel ® Neo Description

White or almost white suspension, with the smell of orange.

Pharmacotherapeutic group

Antacid + carminative

ATX code

Pharmacological properties

Pharmacodynamics
A combined product whose effect is determined by its constituent components. It has an antacid, adsorbent, enveloping, carminative effect. Algeldrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, reduce the acidity of gastric juice, and bind bile acids. The laxative effect of magnesium hydroxide balances the ability of algeldrate to slow down intestinal motility. Simethicone inhibits the formation of gas bubbles and promotes their destruction. The gases released during this process are absorbed by the intestinal walls and removed from the body through peristalsis.
Pharmacokinetics
Simethicone, due to physiological and chemical inertness, is not absorbed into organs and tissues and, after passing through the gastrointestinal tract (GIT), is excreted unchanged. Absorption of aluminum and magnesium ions in the intestines is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the level of aluminum and magnesium in the blood may increase to toxic levels as a result of impaired excretion.

Aomagel ® Neo Indications for use

Acute gastritis; chronic gastritis with increased and normal secretory function of the stomach (in the acute phase); acute duodenitis, duodenogastric reflux; peptic ulcer of the stomach and duodenum (in the acute phase); symptomatic gastrointestinal ulcers of various origins; erosion of the mucous membrane of the upper gastrointestinal tract; gastroesophageal reflux, reflux esophagitis; acute pancreatitis, exacerbation of chronic pancreatitis; gastralgia, heartburn (after excessive consumption of ethanol, nicotine, coffee, taking medications; incorrect diet that negatively affects the functioning of the gastrointestinal tract); flatulence; fermentative or putrefactive dyspepsia.

Contraindications

Hypersensitivity, chronic renal failure, pregnancy, Alzheimer's disease, hypophosphatemia, children under 10 years of age, congenital fructose intolerance.
With caution - lactation period, liver disease, alcoholism, traumatic brain injury, brain diseases, epilepsy, childhood and adolescence from 10 to 18 years.

Aomagel ® Neo Method of administration and dosage

Adults
Orally, 2 scoops or 1 packet of orange-flavored suspension 4 times a day, 1 hour after meals and in the evening before bed. If necessary, the single dose can be increased to 4 scoops or 1 sachet 4 times a day, but the maximum daily dose should not exceed 12 scoops (6 sachets).
Children over 10 years old
The dosage is determined by the attending physician - usually 1/2 dose for adults
The course of treatment is no more than 4 weeks. Before taking, the suspension must be mixed by shaking the bottle or thoroughly kneading the bag. It is advisable to take Almagel ® Neo without diluting with water or drinking it. It is not recommended to take liquids within half an hour after taking the drug.

Side effect

Allergic reactions, nausea, vomiting, changes in taste, constipation, diarrhea. With long-term use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis, impaired renal function. In patients with concomitant renal failure - thirst, decreased blood pressure, hyporeflexia.

Overdose

Symptoms. Prolonged use of high doses can lead to the development of hypermagnesemia, which is characterized by fatigue, facial flushing, exhaustion, muscle weakness and inappropriate behavior.
Signs of metabolic alkalosis may also be observed: mood changes, impaired mental activity, numbness or muscle pain, nervousness and fatigue, slow breathing, unpleasant taste sensations.
Urgent measures. It is necessary to immediately take measures to quickly remove the drug - gastric lavage, inducing vomiting, taking activated charcoal.

Interaction with other drugs

Almagel ® Neo reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamine receptor blockers, beta-blockers, diflunisal, ketoconazole and itraconazole, isoniazid, tetracycline antibiotics and quinolones, azithromycin, cefpodoxime, pivampicillin , rifampicin, indirect anticoagulants, barbiturates, fexofenadine, dipyridamole, zalcitabine, chenodeoxycholic and ursodeoxycholic acids, penicillamine and lansoprazole. M-anticholinergics, by slowing down gastric emptying, enhance and prolong the effect of the drug.

special instructions

The interval between taking Almagel ® Neo and other medications should be 1-2 hours. With long-term use, sufficient intake of phosphorus from food should be ensured. Due to the lack of data from controlled clinical trials, breastfeeding women should take Almagel ® Neo only after consulting a doctor. One measuring spoon (5 ml) of the drug contains 0.113 g of ethyl alcohol. One sachet (10 ml) of the drug contains 0.226 g of ethyl alcohol. As a result, complications may occur in patients with liver and brain diseases, in those suffering from alcoholism and epilepsy, in pregnant women and children under 18 years of age. The daily dose of the drug (8 measuring spoons or 4 sachets) contains 0.904 g of ethyl alcohol, the maximum daily dose of the suspension (12 measuring spoons or 6 sachets) contains 1.356 g of ethyl alcohol. One measuring spoon (5 ml) of Almagel ® Neo contains 0.475 g of sorbitol. One sachet (10 ml) of suspension contains 0.950 g of sorbitol. Sorbitol is contraindicated in people with congenital fructose intolerance and may cause stomach irritation and diarrhea. Almagel ® Neo does not have a negative effect on the ability to drive vehicles and operate mechanisms that require increased concentration and speed of psychomotor reactions.

Release form

Suspension for oral administration.
170 ml or 200 ml of the drug in a glass bottle. Each bottle along with instructions for use and a 5 ml measuring spoon in a cardboard box.
170 ml or 200 ml of the drug in a bottle made of polyethylene terephthalate. Each bottle along with instructions for use and a 5 ml measuring spoon in a cardboard box.
10 ml of the drug in a multilayer foil bag. 10 or 20 sachets along with instructions for use in a cardboard box.

Storage conditions

In a place protected from light at a temperature not exceeding 25°C. Do not freeze!
Keep out of the reach of children!

INSTRUCTIONS
on the use of a medicinal product for medical use

Registration number:

P N 013310/01

Trade name of the drug: Almagel ® Neo

International nonproprietary name:

Algeldrate + Magnesium hydroxide + Simethicone

Dosage form:

Oral suspension

Compound
5 ml (one scoop) of suspension contains:

Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 340 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 395 mg;
Simethicone (simethicone emulsion - in terms of dimethicone) 36 mg;
Content of excipients in 5 ml of suspension: hydrogen peroxide solution 30% 0.495 mg, sorbitol 474.60 mg, sodium saccharinate 1.13 mg, hyaetellose 5.65 mg, citric acid monohydrate 5.65 mg, ethyl parahydroxybenzoate 7.90 mg, propyl parahydroxybenzoate 3.40 mg, propylene glycol 113.00 mg, macrogol 4000 452.00 mg, orange flavor 2.26 mg, ethanol 96% 113.00 mg, purified water up to 5 ml.

10 ml (1 sachet) of suspension contains:

Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 680 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 790 mg;
Simethicone (simethicone emulsion - in terms of dimethicone) 72 mg;
Content of excipients in 10 ml of suspension: hydrogen peroxide solution 30% 0.990 mg, sorbitol 949.20 mg, sodium saccharinate 2.26 mg, hyaetellose 11.30 mg, citric acid monohydrate 1130 mg, ethyl parahydroxybenzoate 15.80 mg, propyl parahydroxybenzoate 6.80 mg, propylene glycol 226.00 mg , macrogol 4000 904.00 mg, orange flavor 4.52 mg, ethanol 96% 226.00 mg, purified water up to 10 ml.

Description
White or almost white suspension, with the smell of orange.

Pharmacotherapeutic group
Antacid + carminative ATX code: A02AF02

Pharmacological properties
Pharmacodynamics
A combined product whose effect is determined by its constituent components. It has an antacid, adsorbent, enveloping, carminative effect. Algeldrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, reduce the acidity of gastric juice, and bind bile acids. The laxative effect of magnesium hydroxide balances the ability of algeldrate to slow down intestinal motility. Simethicone inhibits the formation of gas bubbles and promotes their destruction. The gases released during this process are absorbed by the intestinal walls and removed from the body through peristalsis. Pharmacokinetics Simethicone, due to physiological and chemical inertness, is not absorbed into organs and tissues and, after passing through the gastrointestinal tract (GIT), is excreted unchanged. Absorption of aluminum and magnesium ions in the intestine is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the level of aluminum and magnesium in the blood may increase to toxic levels as a result of impaired excretion.

Indications for use
Acute gastritis; chronic gastritis with increased and normal secretory function of the stomach (in the acute phase); acute duodenitis, duodenogastric reflux; peptic ulcer of the stomach and duodenum (in the acute phase); symptomatic gastrointestinal ulcers of various origins; erosion of the mucous membrane of the upper gastrointestinal tract; gastroesophageal reflux, reflux esophagitis; acute pancreatitis, exacerbation of chronic pancreatitis; gastralgia, heartburn (after excessive consumption of ethanol, nicotine, coffee, taking medications; incorrect diet that negatively affects the functioning of the gastrointestinal tract); flatulence; fermentative or putrefactive dyspepsia.

Contraindications
Hypersensitivity, chronic renal failure, pregnancy, Alzheimer's disease, hypophosphatemia, children under 10 years of age, congenital fructose intolerance. With caution - lactation period, liver disease, alcoholism, traumatic brain injury, brain diseases, epilepsy, childhood and adolescence from 10 to 18 years.

Directions for use and doses

Adults
Orally, 2 scoops or 1 packet of orange-flavored suspension 4 times a day, 1 hour after meals and in the evening before bed. If necessary, the single dose can be increased to 4 scoops or 1 sachet 4 times a day, but the maximum daily dose should not exceed 12 scoops (6 sachets).

Children over 10 years old
The dosage is determined by the attending physician - usually 1/2 dose for adults. The course of treatment is no more than 4 weeks. Before taking, the suspension must be mixed by shaking the bottle or thoroughly kneading the bag. It is advisable to take Almagel ® Neo without diluting with water or drinking it. It is not recommended to take liquids within half an hour after taking the drug.

Side effect
Allergic reactions, nausea, vomiting, changes in taste, constipation, diarrhea. With long-term use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminemia, encephalopathy, nephrocalcinosis, impaired renal function. In patients with concomitant renal failure - thirst, decreased blood pressure, hyporeflexia.

Overdose
Symptoms. Prolonged use of high doses can lead to the development of hypermagnesemia, which is characterized by fatigue, facial flushing, exhaustion, muscle weakness and inappropriate behavior.
Signs of metabolic alkalosis may also be observed: mood changes, impaired mental activity, numbness or muscle pain, nervousness and fatigue, slow breathing, unpleasant taste sensations. Urgent measures. It is necessary to immediately take measures to quickly remove the drug - gastric lavage, inducing vomiting, taking activated charcoal.

Interaction with other drugs
Almagel ® Neo reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamine receptor blockers, beta-blockers, diflunisal, ketoconazole and itraconazole, isoniazid, tetracycline antibiotics and quinolones, azithromycin, cefpodoxime, pivampicillin , rifampicin, indirect anticoagulants, barbiturates, fexofenadine, dipyridamole, zalcitabine, chenodeoxycholic and ursodeoxycholic acids, penicillamine and lansoprazole. M-anticholinergics, by slowing down gastric emptying, enhance and prolong the effect of the drug.

special instructions
The interval between taking Almagel ® Neo and other medications should be 1-2 hours. With long-term use, sufficient intake of phosphorus from food should be ensured. Due to the lack of data from controlled clinical trials, breastfeeding women should take Almagel ® Neo only after consulting a doctor. One measuring spoon (5 ml) of the drug contains 0.113 g of ethyl alcohol. One sachet (10 ml) of the drug contains 0.226 g of ethyl alcohol. As a result, complications may occur in patients with liver and brain diseases, in those suffering from alcoholism and epilepsy, in pregnant women and children under 18 years of age. The daily dose of the drug (8 measuring spoons or 4 sachets) contains 0.904 g of ethyl alcohol, the maximum daily dose of the suspension (12 measuring spoons or 6 sachets) contains 1.356 g of ethyl alcohol. One measuring spoon (5 ml) of Almagel ® Neo contains 0.475 g of sorbitol. One sachet (10 ml) of suspension contains 0.950 g of sorbitol. Sorbitol is contraindicated in people with congenital fructose intolerance and may cause stomach irritation and diarrhea. Almagel ® Neo does not have a negative effect on the ability to drive vehicles and operate mechanisms that require increased concentration and speed of psychomotor reactions.

Release form
Suspension for oral administration.
170 ml or 200 ml of the drug in a glass bottle. Each bottle along with instructions for use and a 5 ml measuring spoon in a cardboard box.
170 ml or 200 ml of the drug in a bottle made of polyethylene terephthalate. Each bottle along with instructions for use and a 5 ml measuring spoon in a cardboard box.
10 ml of the drug in a multilayer foil bag. 10 or 20 sachets along with instructions for use in a cardboard box,

Storage conditions
In a place protected from light at a temperature not exceeding 25°C. Do not freeze! Keep out of the reach of children!

Best before date
2 years.
Do not use after the expiration date stated on the package.

Conditions for dispensing from pharmacies
Over the counter.

Manufacturer
Balkanfarma-Troyan AD, Bulgaria,
5600 Troyan, st. "Krayrechna" No. 1

Consumer complaints should be sent to:
AKTAVIS LLC
127018, Moscow, st. Suschevsky Val, 18