Aminocaproic acid 50. The use of aminocaproic acid in the treatment of children. Drugs similar in their pharmacological actions


Aminocaproic acid is a drug that belongs to the group of hemostatics.

In other words, the use of this pharmacological drug increases blood clotting. That is, aminocaproic acid remarkably stops bleeding.

Scientifically speaking, this medicine makes the process of dissolving blood clots (fibrinolysis) much slower.

However, Aminocaproic acid is a broad-spectrum pharmacological drug. In addition to the hemostatic effect, when instilled into the nose, it has a decongestant and anti-allergic effect on the human body. In addition, when instilled into the nose, this medicine significantly reduces the amount of mucous secretions in various rhinitis (runny nose), as well as flu and colds.

According to the instructions for use of Aminocaproic Acid, it should be stored in a place protected from direct sunlight and out of the reach of children. The proper storage temperature is between 2 and 25 degrees Celsius. Subject to these requirements, the manufacturer declared a guaranteed shelf life of the drug equal to 3 years from the date indicated on the package.

Price

Aminocaproic acid is a democratic and affordable drug for the widest segments of the population. Currently, its price ranges from 28 to 70 rubles per pack.

Indications for use

In accordance with the instructions for the use of aminocaproic acid, indications for its use are bleeding in pathological conditions and surgical interventions of various etiologies (origin). For example, it can be bleeding:

  • during abdominal operations;
  • in dental treatment;
  • with hemorrhagic syndrome;
  • with blood transfusions;
  • with complex abortions;
  • and others.
  • when carrying out preventive measures during epidemics of acute respiratory viral infections and acute respiratory infections;
  • for use in the complex treatment of colds and flu;
  • in the treatment of adenoids in children and adults;
  • in the treatment of the common cold.

Aminocaproic acid with a cold and other cases listed above is instilled directly into the nose.

It can also be used in cases where the patient has observed.

Release form

Aminocaproic acid is currently available in three forms:

  • solution for infusion (5%);
  • tablets;
  • powder.

Depending on the form of release of the drug and the existing problem, it can be taken in different ways:

  • intravenously (dropper);
  • orally (swallowed through the mouth);
  • intranasally (buried in the nose);
  • carrying out inhalations.

The tablet form of aminocaproic acid is taken for chronic diseases and pathological conditions that do not pose an immediate threat to the patient's life. The medicine should be taken three times a day one hour before meals, 1 tablet.

Dosages for intravenous administration of the drug are determined by the attending physician, depending on the existing problematic pathological condition.

Use for instillation into the nose for a cold and flu

When taking prophylactic aminocaproic acid, 1-2 drops of medication should be instilled into each nostril of the nose 4-5 times a day.

When treating an existing disease, children under 16 years of age should instill 2-3 drops of medication into each nasal passage 3-4 times a day. For adults in a similar situation, instill 3-4 drops of the drug in each nasal passage 6-8 times a day.

Contraindications, overdose and side effects

In accordance with the instructions for the use of Aminocaproic acid, its intake is limited to the following contraindications:

  • individual intolerance;
  • hypercoagulation (increased blood clotting);
  • other problems with blood clotting;
  • violation of the blood circulation of the brain;
  • kidney disease.

An overdose of the drug is possible. As a rule, it manifests itself in the onset of side effects. At the first symptoms of an overdose of aminocaproic acid, it is necessary to stop taking it and consult a doctor.

Side effects are:

  • dizziness and headaches;
  • nasal congestion;
  • nausea, diarrhea and vomiting;
  • lowering blood pressure;
  • kidney failure;
  • skin rash;
  • convulsions;
  • myoglobinuria;
  • rhabdomyolysis.

Efficiency and reviews

Aminocaproic acid has good reviews from doctors and their patients. This applies to both its main hemostatic properties and additional uses.

For example, in the treatment of adenoids in children, aminocaproic acid has proven itself well. The same applies to the prevention and treatment of the common cold and colds.

However, given the large number of side effects from taking it, the choice of this drug should definitely be entrusted to the attending physician. It is not necessary to rely solely on comments read somewhere in such a serious matter.

If you have already used Aminocaproic Acid, please leave a review about the effectiveness of the drug.

During pregnancy and lactation

Aminocaproic acid is prohibited for women who are pregnant or breastfeeding.

Analogues

Aminocaproic acid as a remedy for bleeding has the following analogues:

  • Traneksam;
  • Aprotinin;
  • Ingitril;
  • Trenax.

Aminocaproic acid refers to hemostatic drugs. It is considered an inhibitor of fibrinolysis, as well as the transition of plasminogen to plasmin. It is included in preparations for both parenteral administration and topical use.

Pharmacological action of aminocaproic acid

Hemostatic agent Aminocaproic acid is an inhibitor of fibrinolysis. This substance is able to block the action of plasminogen activators, as a result of which plasmin activity is inhibited, kinins are partially suppressed.

In addition, aminocaproic acid has antiallergic activity, but to a small extent, and also slightly enhances liver function, in particular, increases its antitoxic effect.

Aminocaproic acid is rapidly absorbed, the maximum plasma concentration occurs after about two hours. The hemostatic agent quickly enough leaves the body, mainly excreted unchanged in the urine.

Indications of aminocaproic acid for use

This hemostatic agent is indicated for use to stop existing bleeding that may occur during surgical interventions, as well as in various pathological conditions, which are often accompanied by an increase in fibrinolytic activity, for example, during operations on the lungs, on the thyroid, prostate, and also pancreas.

In addition to these conditions, aminocaproic acid is used prophylactically in blood transfusions to prevent the occurrence of secondary hyperfibrinogenemia, which can occur with massive transfusions.

Contraindications of aminocaproic acid for use

Among the contraindications of the drug Aminocaproic acid (solution), instructions for use notes the patient's tendency to thrombosis and embolic manifestations. Do not use this hemostatic drug for severe renal dysfunction, as well as for hypersensitivity to aminocaproic acid.

Aminocaproic acid application and dosage

Adult patients are usually prescribed from 5 to 30 g / day up to six times a day, this is for internal use. Aminocaproic acid for infusion is administered intravenously at five grams directly in the first hour of treatment, and then at a gram every 60 minutes. The maximum daily dosage of Aminocaproic acid should not exceed 30 grams.

Dosages in pediatric practice will be as follows: intravenous infusion is carried out at the rate of 100 mg / kg in the first hour, and then 33 mg / kg per hour. The maximum dose should not exceed 18 g/m2.

It is worth saying that Aminocaproic acid is practically not used to prevent excessive blood loss during labor, this is due to the fact that a hemostatic drug can cause the development of some rather severe thromboembolic complications.

What are the side effects of aminocaproic acid?

Treatment with aminocaproic acid can lead to the development of some side effects that will manifest themselves on the part of many systems and organs, I will dwell on this in more detail.

For example, on the part of the cardiovascular system: the patient may notice the occurrence of interruptions in the region of the heart, that is, arrhythmia joins, in addition, blood pressure decreases, and a slowdown in the heart rate, the so-called bradycardia, also joins.

On the part of the digestive system: there may be dyspeptic side effects, which are usually expressed in the appearance of nausea, sometimes developing into vomiting, in addition, the motor function of the large intestine also suffers, which is expressed in increased peristaltic movements, accompanied by diarrhea.

In addition to the listed conditions, the patient may also notice other side effects, for example, catarrhal phenomena occur in the upper respiratory tract, and slight dizziness also joins.

If side effects, in response to the use of aminocaproic acid, are pronounced and complicate the patient's condition, then it will be necessary to cancel the use of such drugs.

special instructions

With caution, aminocaproic acid is prescribed to the category of patients with a history of recent cerebrovascular accidents. It is not recommended to administer this hemostatic agent in the presence of hematuria, as this can cause the development of acute renal failure, which will require immediate medical correction.

It is worth recalling that the use of this remedy is contraindicated in severe renal dysfunction.

Preparations containing Aminocaproic acid (analogues)

Aminocaproic acid is presented in a dosage form in the form of a powder substance, packaged in special jars or in bags, and a solution of aminocaproic acid is also produced for infusion.

In addition, there is a tool Polycapran, which also includes Aminocaproic acid. There is also the drug Polygemostat, which is intended for external use in the form of a powder.

Conclusion

Before you start using medicines that contain Aminocaproic acid, you should start treatment with them, it is recommended to consult with a qualified specialist! Only after its approval, you can start using such medications.

Aminocaproic acid is known to be quite effective in stopping bleeding. However, in childhood, such a medication can be used in a different way, for example, to be buried in the nose. Is it possible to treat young children with Aminocaproic acid, what are the indications for the use of such a drug in childhood, and how to wash the nose with Aminocaproic acid and how to inhale with such a drug?

Release form

Aminocaproic acid is produced in the form of:

  • Powder or granules. Such aminocaproic acid is distinguished by its white color and the absence of both taste and smell. It easily dissolves in water, forming a solution of a given concentration.
  • 5% solution. It is packaged in bottles with a capacity of 100 ml and 250 ml, as well as in plastic bags or containers with a volume of 100 to 1000 ml. Each milliliter of such a clear liquid without color contains 50 mg of the active substance.

Compound

The main component of the drug is aminocaproic acid. In addition to it, only sterile water, as well as sodium chloride, is present in the solution.

Operating principle

Once in the patient's body, aminocaproic acid affects the blood coagulation process. In particular, it affects the formation of fibrinolysin, inhibiting the activators responsible for this process. It is this effect of the drug that determines its hemostatic effect.

In addition, the drug makes the capillaries less permeable and has an activating effect on platelets. Aminocaproic acid also has a positive effect on the work of the liver to neutralize toxins.

Watch a video that talks about the properties of aminocaproic acid and chlorhexidine:

When instilled into the nasal passages Aminocaproic acid:

  • Reduces the production of pathological secretions in the common cold.
  • Helps reduce swelling of the mucosa.
  • Reduces the inflammatory process.
  • Strengthens the vessels in the nose.
  • It has some antiviral and antiallergic effect.

If aminocaproic acid is taken orally, the drug is well absorbed and after 1-2 hours its concentration in plasma will be maximum. After intravenous administration, the effect of the drug appears after 15-20 minutes.

The kidneys are mainly involved in the excretion of the drug from the body, therefore, the reduced function of this organ leads to a slowdown in excretion and a sharp increase in the amount of aminocaproic acid in the bloodstream.

Indications

Since aminocaproic acid is a hemostatic drug, then bleeding is the most common indication for its use. The drug can be prescribed for bleeding that has already begun, and in order to prevent it. Such a drug is especially in demand in surgery if an operation is planned or performed on the stomach, thyroid gland, lungs and other organs in which there are a lot of fibrinolysis activators. Aminocaproic acid is also prescribed to patients who have received a large volume of blood transfusion.

  • With SARS, a symptom of which is rhinitis.
  • With allergic rhinitis.
  • With bleeding from the vessels of the nose.
  • With sinusitis.
  • At the initial stage of adenoids.
  • To prevent viral infections during the flu season and acute respiratory infections.

At what age is it allowed to take?

Treatment of children with aminocaproic acid is possible from birth, however, the appointment of this medicine for babies of the first year of life should be carried out by a pediatrician.

Without consulting a doctor and individually determining the required dosage, it is unacceptable to use Aminocaproic acid for children under one year of age.

Contraindications

Instructions for use prohibits or restricts treatment with Aminocaproic acid if:

  • There are problems with blood circulation, in which blood clots appear or emboli are detected.
  • Renal failure was found.
  • Seriously impaired liver function.
  • Medication intolerance has been identified.
  • Tests showed blood in the urine.
  • The patient has a serious heart condition.
  • Diagnosed with circulatory disorders in the brain.
  • Reduced blood pressure.

Side effects

The drug is quickly eliminated from the body, and its toxic effect at the correct dosage is minimal, however, in some patients, treatment with Aminocaproic acid leads to:

  • Skin rashes.
  • Acute renal failure.
  • The appearance of vomiting, nausea or loose stools.
  • Headaches.
  • Nasal congestion.
  • Decrease in blood pressure.
  • Vertigo.
  • Destruction of muscle tissue.
  • orthostatic hypotension.
  • Convulsions.
  • Subendocardial hemorrhage.

If such symptoms appear, for example, with vomiting or a skin rash, the dosage of Aminocaproic acid is reduced or treatment with this drug is refused. If, when instilling a nose, the medicine accidentally gets into the eye, you should immediately rinse the mucous membrane and, if the child has complaints from the side of vision, contact an ophthalmologist.

Instructions for use

Methods of administration

Aminocaproic acid can be used:

  • For intravenous injections. This method is most in demand for acute bleeding, as well as during surgical treatment.
  • For oral administration. Such use of the drug is indicated not only for bleeding, but also for rotovirus.
  • For instillation into the nose. Both a ready-made solution and powdered or granular aminocaproic acid mixed with unsweetened water are used (a 5% solution is also prepared from this form of the drug).
  • For inhalation. The procedures are carried out with a nebulizer for adenoids, for coughing, as well as for a long runny nose or sinusitis.
  • For washing the nose. This manipulation is sometimes prescribed to remove yellow or green thick nasal discharge. In this case, the washing must be carried out by a doctor, since an incorrect procedure can cause increased swelling and irritation of the mucosa.

Dosage

  • For the treatment of the common cold one or two drops of liquid aminocaproic acid should be injected into each of the child's nasal passages, unless the doctor has recommended a different dosage. Instillation is repeated every 3 hours, and treatment lasts from three to 7 days.
  • To prevent SARS during the epidemic season, two or three drops of aminocaproic acid in liquid form can be injected into the child's nostrils up to 5 times a day.
  • For one inhalation take a solution of aminocaproic acid in a volume of 2 ml, mixing with the same amount of sodium chloride solution. The frequency of the procedure is twice a day for 5-10 minutes, and the average duration of therapy is 4 days.
  • Into a vein Aminocaproic acid is administered by drip, mixing the drug with saline before infusion. The daily dosage for babies up to a year is 3 grams of the active ingredient, at the age of 2 to 6 years - from 3 to 6 grams of aminocaproic acid, at 7 years and older - from 6 to 9 grams of the active ingredient. If blood loss is acute, the dosage is doubled. Treatment is continued from three to 14 days, depending on the pathology.
  • Inside the drug is given to drink at a dosage of 100 mg per 1 kg of the child's weight, and then every hour until the moment when the bleeding stops at a dose of 33 mg of aminocaproic acid per kilogram of the patient's body weight.

Overdose

If the allowable dose of Aminocaproic acid is exceeded, this will lead to an increase in adverse reactions, as well as to the formation of blood clots. Prolonged use of such a drug in a high dose provokes hemorrhages.

Interaction with other drugs

With simultaneous appointment with antiplatelet agents or any anticoagulants, the effect of Aminocaproic acid is reduced.

Terms of sale

The medicine is sold by prescription. The price of one bottle with 100 ml of aminocaproic acid is an average of 50-60 rubles.

Storage conditions and shelf life


Aminocaproic Acid Powder - antihemorrhagic (hemostatic), hemostatic agent used for bleeding caused by increased fibrinolysis.
The mechanism of specific action is due to competitive inhibition of plasminogen activators and partial inhibition of plasmin activity (in high doses), as well as inhibition of biogenic polypeptides - kinins.
It inhibits the activating effect of streptokinase, urokinase and tissue kinases on the processes of fibrinolysis, neutralizes the effects of kallikrein, trypsin and hyaluronidase, and reduces capillary permeability.
Shows moderate anti-allergic and anti-shock activity; increases the antitoxic function of the liver. It inhibits the proteolytic activity associated with the influenza virus, inhibits the proteolytic activity of hemagglutinin. Improves some cellular and humoral indicators of specific and non-specific protection in respiratory viral infections.
Pharmacokinetics. After oral administration, it is rapidly absorbed in the upper gastrointestinal tract. The maximum concentration in the blood in adults and adolescents is reached after 2 to 3 hours. It practically does not bind to blood proteins. Partially (10 - 15%) biotransformed in the liver; the rest is excreted by the kidneys mainly unchanged. During the day, about 60% of the administered dose is excreted from the body (with normal kidney function).
In case of violation of the urinary function, cumulation of the drug is possible.

Indications for use

Indications for the use of the powder Aminocaproic acid are: prevention and treatment of parenchymal bleeding, hemorrhage from the mucous membranes, menorrhagia, bleeding from erosions and ulcers of the stomach and intestines. Prevention of bleeding during operations on the liver, lungs, pancreas. Various types of hyperfibrinolysis, including those associated with the use of thrombolytic drugs and massive transfusion of canned blood. As a symptomatic remedy - bleeding due to thrombocytopenia and qualitative inferiority of platelets (dysfunctional thrombocytopenia).

Mode of application

Powder Aminocaproic acid appoint inside, during or after a meal, dissolving the powder in sweet water or drinking it. The daily dose for adults is divided into 3-6 doses, for children - 3-5 doses.
Moderately pronounced increase in fibrinolytic activity. Adults are usually prescribed in a daily dose of 5-24 g (5-24 packets).
For children under 1 year of age, a single dose is 0.05 g / kg of body weight (but not more than 1 g). The daily dose for children is: under the age of 1 year - 3 g (3 packages), 2 - 6 years - 3 - 6 g (3 - 6 packages), 7 - 10 years - 6 - 9 g (6 - 9 packages) . For adolescents, the maximum daily dose is 10 - 15 g (10 - 15 packets).
Acute bleeding (including gastrointestinal). Adults are prescribed 5 g (5 packets), then 1 g (1 packet) every hour (for no more than 8 hours) until the bleeding stops completely. Daily dose for children with acute blood loss: under the age of 1 year - 6 g (6 packages), 2 - 4 years - 6 - 9 g (6 - 9 packages), 5 - 8 years - 9 - 12 g (9 - 12 packages), 9 - 10 years -
18 g (18 packets).
Subarachnoid hemorrhage. Adults appoint a daily dose of 6 - 9 g (6 - 9 packets).
Traumatic hyphema. Assign at a dose of 0.1 g / kg of body weight every 4 hours (but not more
24 g/day) for 5 days.
Metrorrhagia associated with intrauterine devices. Assign 3 g (3 packets) every 6 hours.
Prevention and control of bleeding during dental interventions. Adults appoint 2 - 3 g (2 - 3 packages) 3 - 5 times a day.
For adults, the average daily dose is 10 - 18 g (10 - 18 packets), the maximum daily dose is 24 g (24 packets).
The course of treatment is 3 - 14 days.
The duration of treatment is determined individually and depends on the severity of the disease. According to the indications, repeated courses of treatment are possible.

Side effects

From the side of the cardiovascular system: orthostatic hypotension, subendocardial hemorrhage, bradycardia, arrhythmias. From the digestive system: nausea, diarrhea. From the blood coagulation system: with prolonged use (more than 6 days) of high doses (for adults - more than 24 g per day) - hemorrhages. From the side of the central nervous system: headache, dizziness, tinnitus, convulsions. Other: catarrhal phenomena of the upper respiratory tract, skin rash, myoglobinuria, rhabdomyolysis, acute renal failure.
Side effects are rare and dose dependent; when the dose is reduced, they usually disappear.

Contraindications

:
Powder contraindications Aminocaproic acid are: increased individual sensitivity to aminocaproic acid, a tendency to thrombosis and embolism, all hereditary and secondary thrombophilias, disseminated intravascular coagulation syndrome, gross hematuria, severe renal dysfunction, pregnancy, lactation.

Pregnancy

:
Powder Aminocaproic acid contraindicated in pregnancy. It is inappropriate to use in women in order to prevent increased blood loss during childbirth, since thromboembolic complications may occur. If necessary, use during lactation, breastfeeding should be discontinued.

Interaction with other drugs

When taking the powder Aminocaproic acid inside well combined with thrombin. The effect of the drug is weakened by antiplatelet agents and anticoagulants of direct and indirect action. Combined use with estrogen-containing contraceptives, blood coagulation factor IX increases the risk of thromboembolism.

Overdose

:
Powder overdose symptoms Aminocaproic acid: increased side effects, the formation of blood clots, embolism. With prolonged use, it is possible to develop the opposite effect - hemorrhage.
Treatment: drug withdrawal, symptomatic therapy.

Storage conditions

Store in a dry place at temperatures between 8°C and 25°C. Keep out of the reach of children.
Shelf life 2 years.

Release form

Aminocaproic acid - powder for oral administration.
1 g of powder in bags No. 1 or in coupled bags No. 2, or in coupled bags No. 4 (No. 2x2), No. 10 (2x5) in a cardboard box.

Compound

:
1 packet of powder Aminocaproic acid contains aminocaproic acid 1 g.

Additionally

:
Precautions are prescribed for heart disease, liver and / or kidney failure.
It is not recommended to use the drug for hematuria (due to the risk of developing acute renal failure).
With prolonged use (more than 6 days) of high doses (more than 24 g per day for adults), hemorrhages may occur due to inhibition of platelet aggregation and adhesion.
With menorrhagia, it is effective to take from the first to the last day of menstruation.
During drug therapy, it is recommended to check the fibrinolytic activity of the blood and the level of fibrinogen.

main parameters

Name: AMINOCAPRONIC ACID POWDER

It is important to know what aminocaproic acid is, since its use in medicine is very wide (photos of packages and the name of manufacturers are easy to find on the Internet). effectively stops bleeding, including from the so-called shock organs (for example, from the uterus). For this reason, the drug is indispensable in many situations that threaten the development of severe pathological conditions and are life-threatening for the patient.

This medicinal product reduces the activity of the thrombus resorption process, or fibrinolysis. A similar effect is achieved due to the fact that aminocaproic acid helps to reduce the activity of the enzymes responsible for this phenomenon - we are talking about plasmin and plasminogen. Besides, the drug also affects other substances that inhibit the activity of the coagulation system.

Aminocaproic acid has a number of additional properties - it reduces the severity of inflammation and hyperreactivity reactions, reduces the production of antibodies (immunosuppressive effect).

The drug is produced in the form of a solution intended for intravenous administration, and tablets for oral administration. Each form contains a certain amount of aminocaproic acid. In 100 ml of solution there are 5 g of aminocaproic acid. Tablets of this remedy contain 500 mg of active ingredient.

The choice of dosage form depends on the nature and severity of the pathology, carried out only by a doctor. When administered intravenously, the drug begins to act instantly. When using tablet forms, you need to wait a little - an average of 20 minutes. The effect of oral administration is also pronounced, since the agent is quickly and almost completely absorbed from the gastric mucosa.

Indications for use

The drug is indicated to eliminate and prevent the occurrence of bleeding as a result of increased fibrinolysis or with a significant decrease (sometimes even complete absence) of this protein in the body. Other indications for the use of aminocaproic acid are as follows:

  1. Carrying out surgical intervention on such organs as the prostate, uterus, pancreas, thyroid gland, brain, lungs, adrenal glands. This is necessary because these operations have a high risk of bleeding.
  2. Carrying out extracorporeal circulation.
  3. The use of aminocaproic acid after surgical interventions performed on the heart and blood vessels is common.
  4. Treatment of burn disease.
  5. The drug is widely used in gynecology - with uterine bleeding, placental abruption, abortions with complications.
  6. 5% aminocaproic acid is shown in the surgical treatment of pathologies of the otorhinolaryngological profile, including to stop bleeding from the nasal cavity.
  7. Diseases of the hematopoietic system - malignant anemia, bone marrow tumors.

In general, this drug used to eliminate the outflow of blood from almost any localization, as well as for the prevention of this pathological condition during massive blood transfusions.

Contraindications and side effects

Aminocaproic acid, like any drug, has contraindications for use. The drug is not used if patients have hypersensitivity reactions to the main and auxiliary components means, conditions of hypercoagulability, in which there is a high risk of formation of blood clots in the vessels and subsequent thromboembolism.

Also, the drug is not used for circulatory disorders in the central nervous system and kidneys, disseminated intravascular coagulation syndrome. A drug contraindicated during pregnancy, aminocaproic acid is not prescribed for bleeding from the upper airways of unclear etiology.

This medicinal product can cause the following side effects:

  1. The destruction of muscle tissue, or rhabdomyolysis, which also leads to acute renal failure and myoglobinuria.
  2. Decreased blood pressure and heart rate.
  3. Headaches and dizziness, noise in the head and ringing in the ears.
  4. Hemorrhages in the subendocardial space.
  5. Various disorders of cardiac conduction (arrhythmias).
  6. orthostatic hypotension.
  7. It is important to note that acute renal failure while taking this drug can develop without destroying muscle tissue.

Also, aminocaproic acid can cause occurrence of allergic reactions. Usually the latter are diagnosed in the form of rashes, but in severe cases, the appearance of angioedema can be observed.

If symptoms of overdose appear- lowering blood pressure, the development of renal failure, the drug must be stopped immediately. The patient is treated symptomatically, he must be taken to a medical institution for hemodialysis in order to remove the drug from the body.

Instructions for use

Instructions for using a solution of aminocaproic acid inside are quite simple, as well as tablet forms. In an acute condition, 100 ml of the drug is immediately injected intravenously, up to 5 g of the active substance is allowed in 60 minutes. Then you can enter 1 g of aminocaproic acid hourly until the bleeding stops.

The duration of use in such situations is a maximum of 8 hours. if blood continues to flow, a second infusion can be done after 4 hours. The same doses of the drug are calculated using tablet forms.

Aminocaproic acid is prohibited for use in the treatment of pregnant women. As for the lactation period, when using this drug recommended not to breastfeed.

Features of use for children

Aminocaproic acid is prescribed for children who have reached the age of 2 years. The dosage is calculated depending on the body weight of the child. Patients aged 2 to 4 years a single dose of 1 g is indicated, the maximum daily amount is 6 g.

Patients who 5 to 8 years up to 1.5 g of aminocaproic acid can be given as a single dose, the daily dose should not exceed 9 g. if the age of small patients is within 9-10 years old, then their single dose of the drug is 3 g, daily - 18 g.

For older persons, the dosage of aminocaproic acid is calculated in the same way as for adults. The indicated quantities of the drug are suitable for calculating both solution and tablets.

The duration of therapy with this drug usually does not exceed 2 weeks., in some cases it can be extended up to 4 weeks or even more. The dosage of the medication taken and the timing of the intake are set and adjusted only by the doctor. During the period of therapy, constant monitoring of the parameters of the general blood test, as well as supervision by medical personnel, is necessary. This applies to pediatric and adult patients.

Conclusion

Patients need to have information on how to drink aminocaproic acid correctly, know the indications for its use, as well as contraindications and what side effects are possible as a result of using this drug.

The drug is necessary to stop bleeding, so it can save the life of patients, as well as help avoid complications as a result of a large number of operations. The drug is used strictly according to indications, only as prescribed by a doctor, independent use is unacceptable.