Endocrinology: national guidance - Dedov I.I. Endocrinology Other books on similar topics

Full Member of the Russian Academy of Medical Sciences, Director of the Scientific Endocrinology Center of the Russian Academy of Medical Sciences, Director of the Federal Diabetology Center of the Ministry of Health of the Russian Federation, Head of the Department of Endocrinology of the Moscow Medical Academy. I. M. Sechenov; graduated from the Voronezh Medical Institute, graduate school of the Academy of Medical Sciences, Doctor of Medical Sciences, Professor; worked at the Institute of Medical Radiology of the USSR Academy of Medical Sciences (Obninsk), at the First Moscow Medical Institute named after. Sechenov as a professor in the department of faculty therapy for the course of endocrinology, since 1989 - head of the department of endocrinology; in 1989 he headed the Endocrinological Research Center of the USSR Academy of Medical Sciences; President of the Russian Association of Endocrinologists, chief freelance endocrinologist of the Ministry of Health of the Russian Federation, WHO expert on diabetes mellitus, member of the European and International Associations of Diabetologists; awarded the Order of Friendship (1994), the Order of Merit for the Fatherland, IV degree (2001).

Other books on similar topics:

Author	Book	Description	Year	Price	Book type
Dedov I.I.		-	2019	3918	paper book
Dedov Ivan Ivanovich	Endocrinology. National leadership	National guidelines are a series of practical guidelines for the main medical specialties, including special information necessary for a doctor for continuing postgraduate education. In… - GEOTAR-Media, National Guide	2019	4866	paper book
Dedov I.I.	Endocrinology. National leadership	National guidelines are a series of practical guidelines for the main medical specialties, including special information necessary for a doctor for continuing postgraduate education. In… - GEOTAR-Media,	2019	4495	paper book
		National guidelines are a series of practical guidelines for the main medical specialties, including special information necessary for a doctor for continuing postgraduate education. In… - GEOTAR-Media,	2018	1854	paper book
Dedov I.I.	Endocrinology. National leadership. Brief edition		2018	1402	paper book
	Endocrinology. National leadership. Brief edition	National guidelines are a series of practical guidelines for the main medical specialties, including special information necessary for a doctor for continuing postgraduate education. In… - GEOTAR-Media, National guidelines. Short version	2018	1556	paper book

NATIONAL GUIDELINES

Brief edition

The publication that you are holding in your hands is the result of painstaking work, long thoughts, creative impulses and a synthesis of many years of experience of practicing medical specialists, experts and leaders of medical societies. This is a more compact and easier-to-use version of the book of the same name from the famous National Guides series. We have tried to update and reduce the text to a minimum so that you can freely use it in your everyday work - at the patient's bedside, in the resident's room or at the reception. We hope that this book will help avoid many diagnostic errors and incorrectly prescribed treatment.

In this book you will find answers to important practical questions:

y Latest changes in the treatment algorithm for diabetes mellitus Type 2.

y Advantages and disadvantages of new drugs for the treatment of diabetes.

y Features of diabetes management in intensive care and in the perioperative period.

y Principles of treatment of various forms of thyroid cancer.

y Diagnostic approaches for incidentally detected formations of the pituitary gland and adrenal glands.

y Tactics for managing emergency conditions in endocrinology.

More detailed information is presented in the book “Endocrinology. National leadership" (edited by I.I. Dedov, G.A. Melnichenko. M.: GEOTAR-Media, 2009. 1072 pp.) and in the electronic information and educational system "Doctor's Consultant" on CD (M. : GEOTAR-Media, 2008).

ENDOCRINOLOGY
SHORT EDITION	NATIONAL LEADING

Russian Association of Endocrinologists

ENDOCRINOLOGY

ASSOCIATION

MEDICAL

COMPANIES BY QUALITY

ENDOCRINOLOGY

NATIONAL GUIDELINES SHORT EDITION

Edited by

acad. RAS and RAMS I.I. Dedova, Corresponding Member RAMS G.A. Melnichenko

Prepared under the auspices of the Russian Association of Endocrinologists

and the Association of Medical Societies for Quality

UDC 616.4(035) BBK 54.15

A short edition of the national guidelines is recommended by the Russian Association of Endocrinologists

and the Association of Medical Societies for Quality

E64 Endocrinology. National leadership. Brief

edition / ed. I. I. Dedova, G. A. Melnichenko. - M.:

GEOTAR-Media, 2013. - 752 p. ISBN 978-5-9704-2471-1

The publication is a shortened version of the book “Endocrinology. National Guidelines,” published in 2009 under the auspices of the Russian Association of Endocrinologists and the Association of Medical Societies for Quality.

Leading Russian specialists took part in the revision of the manual. The editorial board was composed of chief specialists, experts from the Russian Ministry of Health, heads of professional medical societies, academicians of the Russian Academy of Sciences and the Russian Academy of Medical Sciences, heads of research institutions and medical universities.

The relevance of the publication of this book is dictated by the limited selection on the medical literature market of domestic compact manuals of this level for everyday use by doctors.

The manual will be of interest not only to endocrinologists, but also to residents, senior students, and doctors of related specialties.

UDC 616.4(035) BBK 54.15

The authors, editors, and publishers of this guide have made every effort to ensure the accuracy of the information presented, including drug dosages. Given the constant changes occurring in medical science, we recommend that the dosage of medications be updated according to the appropriate instructions. Patients cannot use this information for diagnosis or self-medication.

The rights to this publication belong to LLC Publishing Group "GEOTAR-Media". Reproduction and distribution in any form of part or the whole publication cannot be carried out without the written permission of the GEOTAR-Media Publishing Group LLC.

Publication contributors........................................................ ............................
List of abbreviations and symbols....................................
Chapter 1. Clinical diagnostic methods.................................................
Collection of complaints, medical history, examination of the body.................................................... .
Palpation of the thyroid gland............................................................ ..
Examination and palpation of the mammary glands..................................................
Measuring growth and assessing it.................................................................... ........
Assessment of sexual development................................................................... ..........
Assessing the degree of hirsutism................................................................... ..........
Examination for polyneuropathy of the lower extremities......
Chapter 2. Laboratory diagnostic methods....................................
Biochemical analysis of blood and urine....................................................
Hormonal analysis of blood and urine....................................................
Immunological blood test...................................................................
Diagnostic tests......................................................... ...............
Molecular genetic diagnostics....................................................
Chapter 3. Instrumental diagnostic methods....................................
Computed tomography of the adrenal glands..................................
Magnetic resonance imaging of the pituitary gland..................................
Magnetic resonance imaging of the adrenal glands............................
X-ray of the sella turcica.................................................... .
X-ray of the spine................................................... ...
Whole body scintigraphy................................................................... ............
Scintigraphy of the parathyroid glands.................................................
Thyroid scintigraphy............................................................
Fine needle aspiration biopsy of the thyroid
glands........................................................ .........................................
Ultrasound examination of the parathyroid glands.......
Ultrasound examination of the thyroid gland...................
Chapter 4. Pharmacotherapy........................................................ ............
Antihyperglycemic drugs............................................................. ..
Drugs for the treatment of thyroid diseases....
Drugs for the treatment of neuroendocrine diseases....
Sex hormone preparations................................................................... ...
Drugs affecting phosphorus-calcium metabolism......
Drugs that reduce body weight....................................................
Chapter 5. Non-drug treatment....................................................
Diet therapy......................................................... ............................
Physical exercise................................................ ............
Chapter 6. Radiation methods of treatment.................................................... ...
Radioiodine therapy......................................................... .......................
Radiological methods of treatment of pituitary adenomas....................
Chapter 7. Surgical methods of treatment....................................
Surgical treatment of thyroid diseases...
Surgical treatment of adrenal diseases.................................
Surgical treatment of pituitary adenomas....................................

Chapter 8. Program hemodialysis....................................................
Chapter 9. Laser coagulation of the retina....................................................
Chapter 10. Diabetes mellitus.................................................... .............
	Diabetes mellitus type 1................................................... ............
	Diabetes mellitus type 2................................................... ............
	Gestational diabetes mellitus................................................................... .
	Diabetic ophthalmopathy................................................................. .
	Diabetic neuropathy................................................................ ........
	Diabetic nephropathy................................................................. .......
	Diabetic foot syndrome................................................................... ..
	Management of diabetes mellitus and stress hyperglycemia
	during intensive care and perioperative
	period........................................................ ........................................
	Hypoglycemia and hypoglycemic coma.................................................
	Hyperosmolar hyperglycemic state..................
	Lactate acidosis................................................... ...............................
	Diabetic ketoacidosis and ketoacidotic coma.........
Chapter 11. Obesity and metabolic syndrome..................................
	Obesity................................................. ....................................
Chapter 12. Diseases of the thyroid gland....................................................
	Hypothyroidism syndrome................................................... .............
	Thyrotoxicosis syndrome................................................... ..........
	Nodular goiter syndrome................................................................... ...............
	Amiodarone-induced thyropathies.................................................
	Chronic autoimmune thyroiditis.................................................
	Graves–Bazedow disease................................................................. ..........
	Diffuse euthyroid goiter.................................................................... ..
	Colloid nodular goiter.................................................... ............
	Subacute thyroiditis................................................... ................
	Thyroid cancer................................................................... .............
	Endocrine ophthalmopathy................................................................. ....
	Thyrotoxic crisis................................................... ..............
	Hypothyroid coma................................................... .............
Chapter 13. Neuroendocrine diseases....................................
	Incidentaloma of the pituitary gland............................................................ ..........
	Empty sella syndrome....................................................
	Hyperprolactinemia syndrome................................................................. .
	Acquired hypopituitarism syndrome
	(in adults)......................................................... ...................................
	Syndrome of inappropriate antidiuretic secretion
	hormone........................................................ .......................................
	Tall syndrome................................................................... ..........
	Short stature syndrome................................................................... ............
	Acromegaly and pituitary gigantism....................................
	Itsenko–Cushing's disease.................................................... ..........
	Hormone-inactive pituitary tumors..................................
	Neuroendocrine tumors................................................................... .....

Diabetes insipidus......................................................... ....................
Prolactinoma........................................................ ............................
Chapter 14. Diseases of the adrenal glands.................................................. .
Incidentaloma of the adrenal gland................................................................. ..
Hyperaldosteronism syndrome....................................................
Hypercortisolism syndrome................................................... ........
Hypocortisolism syndrome................................................... ..........
Primary hyperaldosteronism....................................................
Congenital dysfunction of the adrenal cortex....................................
Corticosteroma........................................................ ........................
Acute adrenal insufficiency.................................................
Primary adrenal insufficiency....................................
Pheochromocytoma......................................................... .......................
Chapter 15. Disorders of phosphorus-calcium metabolism..................
Hypercalcemia syndrome................................................... .......
Hypocalcemia syndrome................................................... .........
Hyperparathyroidism syndrome................................................... .......
Hypoparathyroidism syndrome................................................................. .........
Osteoporosis................................................. ........................................
Osteomalacia syndrome................................................................... ..............
Paget's disease................................................... ........................
Primary hyperparathyroidism................................................................. ....
Chapter 16. Reproductive endocrinology....................................
Amenorrhea syndrome................................................... ......................
A typical form of gonadal dysgenesis (Shereshevsky–
Turner) ..................................... .......................................
Functional disorders of the hypothalamic-pituitary
Organic disorders of the hypothalamic-pituitary
systems........................................................ .......................................
Malformations of the genital organs....................................................
Uterine aplasia (Mayer–Rokitansky–
Kustner) .................................................... ....................................
Secondary amenorrhea................................................... ...................
Pathology of the uterus................................................... ........................
Intrauterine synechiae (Asherman's syndrome).................................
Amenorrhea due to weight loss....................................................
Psychogenic amenorrhea................................................................. ...............
Hyperprolactinemia......................................................... .............
Resistant ovarian syndrome.................................................................
Ovarian wasting syndrome................................................................. ...
Ovarian hyperinhibition syndrome....................................................
Hermaphroditism syndrome................................................................. .......
Hyperandrogenism syndrome in women....................................................
Hypogonadism syndrome in men....................................................
Gynecomastia syndrome................................................................... ..............
Precocious puberty syndrome...................
Delayed puberty syndrome...................................................

	Functional delay of sexual development......................
	Hypogonadotropic hypogonadism....................................................
	Kallmann's syndrome................................................... ....................
	Isolated hypogonadotropic hypogonadism......
	Multiple congenital tropic hormone deficiency
	pituitary gland........................................................ ....................................
	Congenital adrenal hypoplasia and
	hypogonadotropic hypogonadism in boys
	(DAX1 gene mutation) .................................................... ....................
	Congenital multiple combined defects
	development........................................................ ......................................
	Acquired forms of hypogonadotropic
	hypogonadism......................................................... ............................
	Hypergonadotropic hypogonadism....................................................
	Age-related androgen deficiency in men..................................
	Menopausal syndrome................................................................ ......
	Polycystic ovary syndrome....................................................
	Klinefelter's syndrome (hypergonadotropic
	hypogonadism) ................................................... ............................
Chapter 17. Autoimmune polyglandular syndromes.........
Chapter 18. Multiple endocrine syndromes
neoplasia........................................................ .......................................
	1st type......................................................... .........................................
	Multiple endocrine neoplasia syndrome
	2nd type................................................... .........................................
Subject index................................................ ...................

PUBLICATION PARTICIPANTS

Chief editors

Dedov Ivan Ivanovich- academician RAS and RAMS, Dr. med.

Sci., prof., director of the Endocrinological Research Center of the Ministry of Health of the Russian Federation, head. Department of Endocrinology of the First Moscow State Medical University

them. THEM. Sechenova, head of the Federal Agency for Higher

juice-tech medical care

Melnichenko Galina Afanasyevna - corresponding member. RAMS, Dr. honey. sciences, prof. Department of Endocrinology of the First Moscow State Medical University

them. THEM. Sechenova, Director of the Institute of Clinical Endocrine

logy of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Executive Editor

Ilovaiskaya Irena Adolfovna

Scientific editors

Ilovaiskaya Irena Adolfovna - Ph.D. honey. Sci., senior researcher at the Department of Therapeutic Endocrinology of MONIKI named after. M.F. Vladimirsky

Fomin Alexey Anatolievich- Ph.D. honey. sciences, teaching

Head of the Department of Therapy, State Institute for Advanced Training of Physicians, Ministry of Defense of the Russian Federation

Reviewers

Grineva Elena Nikolaevna- Dr. med. sciences, prof., director

Institute of Endocrinology of the Federal Center for Heart, Blood and

endocrinology named after. V.A. Almazova

Mkrtumyan Ashot Musaelovich- Dr. med. Sciences, prof., head.

Department of Endocrinology and Diabetology of the Moscow State

National Medical and Dental University

Suplotova Lyudmila Aleksandrovna - Dr. med. sciences, pro-

rector for medical work of the Tyumen State Medical Academy, chief endocrinologist of the Tyumen region

Abramova Nadezhda Alexandrovna - Ph.D. honey. sciences, assistant Andreeva Elena Nikolaevna - Dr. honey. sciences, head Department of Endocrine Gynecology, Endocrinological Scientific

Center of the Ministry of Health of the Russian Federation

Artemova Alla Mikhailovna- ultrasound diagnostic doctor

statistics of the Department of Functional Diagnostics of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Beltsevich Dmitry Germanovich - Dr.

Butrova Svetlana Alexandrovna - Ph.D. honey. Sci., Leading Researcher, Department of Endocrinological Therapy

Scientific Center of the Ministry of Health of the Russian Federation

Bukhman Adolf Isaakovich- Dr. med. Sciences, Chief Researcher of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Vanushko Vladimir Eduardovich - Dr. honey. Sci., Chief Researcher, Department of Endocrine Surgery, Endocrinological Research Center, Ministry of Health of the Russian Federation

Vorontsov Alexander Valerievich - Dr. med. sciences, prof.,

head Department of Functional Diagnostics and Magnetic Resonance Imaging of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Galstyan Gagik Radikovich- Dr. med. sciences, head department

diabetic foot, Endocrinological Research Center of the Ministry of Health of the Russian Federation

Gevorkyan Marianna Aramovna- Dr. med. sciences, prof. Department of Obstetrics and Gynecology, Faculty of Medicine, Moscow State Medical and Dental University

Glinkina Irina Vladimirovna - Ph.D. honey. sciences, assistant

Department of Endocrinology of the First Moscow State Medical University named after. THEM. Sechenov

Grigoriev Andrey Yurievich- Ph.D. honey. Sci., Head of Neurosurgical Group, Senior Researcher

Endocrinological Research Center of the Ministry of Health of the Russian Federation

Grigoryan Olga Rafaelevna - Dr. honey. Sci., Chief Researcher, Department of Endocrine Gynecology, Endocrinological Research Center of the Ministry of Health of the Russian Federation

Gurova Olesya Yurievna- endocrinologist of the Clinic en-

Docrinology of the First Moscow State Medical University named after. THEM. Sechenov

Davydov German Anatolievich- Ph.D. honey. sciences, head department

of radionuclide diagnostics of Medical radiology

Scientific Research Center of the Russian Academy of Medical Sciences (Obninsk)

Derkach Dmitry Anatolievich - Ph.D. honey. Sciences, doctor from

division of endocrine gynecology of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Dzgoeva Fatima Khadzhimuratovna - Ph.D. honey. sciences, doctor-nutritionist-endocrinologistEndocrinological Research Center of the Ministry of Health of the Russian Federation

Dzeranova Larisa Konstantinovna - Dr. med. sciences, leading

Senior Researcher, Department of Neuroendocrinology and Osteopathy, Endocrinological Research Center, Ministry of Health of the Russian Federation

Ilovaiskaya Irena Adolfovna - Ph.D. honey. sciences, senior

Researcher at the Department of Therapeutic Endocrinology

MONIKA them. M.F. Vladimirsky

Ilyin Alexander Viktorovich - manager Laboratory of Clinical Biochemistry of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Kalinchenko Svetlana Yurievna - Dr. honey. sciences, prof. Department of Clinical Andrology, Head. Department of Endocrinology

FPCMR RUDN

Koloda Dmitry Evgenievich - endocrinologist Latkina Nonna Vladimirovna - Ph.D. honey. sciences, doctor-

surgeon of the department of endocrine surgery of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Lepetukhin Alexander Evgenievich - Ph.D. honey. Sci., Researcher, Department of Uroandrology, Endocrinology

scientific center of the Ministry of Health of the Russian Federation

Lipatov Dmitry Valentinovich - Dr. honey. sciences, head Department of Diabetic Retinopathy and Ophthalmic Surgery of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Mayorov Alexander Yurievich - Ph.D. honey. sciences, leading

Researcher, Department of Psychosocial Rehabilitation and Education of Patients with Diabetes Mellitus, Endocrinological Research Center of the Ministry of Health of the Russian Federation

Manchenko Oksana Vladimirovna - Ph.D. honey. Sciences, radiologist, senior researcher at the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Mokrysheva Natalya Georgievna - Ph.D. honey. sciences, leading

Researcher, Department of Neuroendocrinology and Osteopathy, Endocrinological Research Center, Ministry of Health of the Russian Federation

Oleinik Natalya Andreevna- doctor of the highest category from -

division of radionuclide diagnostics of the Medical Radiological Research Center of the Russian Academy of Medical Sciences (Obninsk)

Orlova Elizaveta Mikhailovna - Ph.D. honey. Sci., senior researcher at the Institute of Pediatric Endocrinology

nological scientific center of the Ministry of Health of the Russian Federation

Pavlova Maria Gennadievna- Ph.D. honey. sciences, assistant

Department of Endocrinology of the First Moscow State Medical University named after. THEM. Sechenov

Peterkova Valentina Aleksandrovna - Dr. med. sciences,

prof., director of the Institute of Pediatric Endocrinology Endocrinology

Logical Research Center of the Ministry of Health of the Russian Federation

Petunina Nina Aleksandrovna - Dr. honey. sciences, prof. cafe-

Doctor of Endocrinology, Faculty of Postgraduate Education, First Moscow State Medical University named after. THEM. Sechenov

Pigarova Ekaterina Alexandrovna - Researcher at the Department of Neuroendocrinology and Osteopathy of the Endocrinological Research Center of the Ministry of Health of the Russian Federation

Prokofiev Sergey Alexandrovich - Ph.D. honey. sciences, head genetic laboratory of the Endocrinological Scientific

Center of the Ministry of Health of the Russian Federation

Pronin Vyacheslav Sergeevich- Ph.D. honey. sciences, head department

Department of Diabetology of the Endocrinology Clinic of the First Moscow State Medical University named after. Sechenov

National guidelines are a series of practical guidelines for the main medical specialties, including special information necessary for a doctor for continuing postgraduate education. Unlike other publications, national guidelines pay equal attention to prevention, diagnosis, pharmacotherapy and non-drug treatment methods.

The national guide “Endocrinology” provides modern recommendations for the prevention, diagnosis, treatment of endocrine diseases and rehabilitation of endocrinological patients. Particular attention is paid to the management of patients with the most common diseases of the endocrine system, such as diabetes mellitus, obesity, osteoporosis, and thyroid diseases. Recommendations for the diagnosis, treatment and prevention of endocrine diseases were prepared by leading experts and reflect the united, coordinated position of the national scientific school.

In this second edition, all sections of the manual have been revised and updated, taking into account the latest international and domestic recommendations.

The manual is intended for endocrinologists, therapists, general practitioners, as well as senior students of medical universities, interns, residents, and graduate students.

The National Guide to Endocrinology is a fundamental work reflecting the current level of development of clinical endocrinology, work on which was carried out under the auspices of the Russian Association of Endocrinologists with the active participation of employees of the largest research institutions in Moscow, St. Petersburg and other cities of Russia. Thanks to the unification of the majority of leading endocrinologists in Russia into a team of authors, it was possible to create a guide that reflects the agreed position of the national scientific school on all current problems of endocrinology. In Russia, as in most developed countries of the world, endocrine diseases, in particular diabetes mellitus, are one of the main causes of mortality and disability.

In the book “Endocrinology. National Guide" provides modern recommendations for the prevention, diagnosis, treatment of endocrine diseases and rehabilitation of endocrinological patients. Particular attention is paid to the management of patients with the most common diseases of the endocrine system, such as diabetes mellitus, obesity, osteoporosis, and thyroid diseases. Diagnostic approaches to patients with the most common endocrinological syndromes are outlined: hypercortisolism, nodular goiter, hypogonadism, etc. Recommendations for diagnosis and treatment are based on extensive clinical experience of leading domestic institutions and on the results of multicenter scientific studies conducted both in our country and abroad. abroad. The continuous development of medicine (new clinical studies, recommendations, pharmacological drugs) necessitated the need to revise and refine the national guide to endocrinology and release the second edition of the book.

In accordance with the latest advances in medical technology, the authors made corrections and additions to the second edition of the national guide to endocrinology, and also wrote new relevant sections. The tactics of patient management are described in more detail, taking into account the latest international recommendations. The mechanisms of action of pharmacological drugs are examined in detail and previously undescribed groups of medicinal substances that have proven themselves since the release of the first edition have been added. We hope that the information contained in the manual will serve as a standard for the provision of endocrinological care in Russia and will contribute to a further reduction in morbidity and mortality from endocrine diseases. diseases.

Any comments and suggestions for improving this manual will be gratefully accepted by the authors and taken into account when reprinting the book.