The medicine. Health. Geksoral aerosol - instructions for use Geksoral instructions for use


Antiseptic for the oral cavity, which is available in the form of a spray and rinse solution. The active substance exhibits bactericidal activity against most bacteria, as well as fungi of the genus Candida. Can be used in adults and children. When used correctly, it does not cause adverse reactions and acts only locally.

Dosage form

Hexoral is an antiseptic drug that is used for diseases of the oral mucosa and gums. The drug is available in 2 forms:

  1. Solution. It is a clear red liquid. It has a mint flavor. The drug is available in vials of 200 ml. The tool is sold in cardboard packs.
  2. Spray can. A clear liquid with the smell of menthol is placed in a 40 ml bottle. It comes with a spray nozzle. The cylinder, instructions and sprayer are placed in a cardboard box.

Description and composition

The main active ingredient of the drug is hexetidine. It is antiseptic and kills most known bacteria. The medicine also contains auxiliary substances, the list of which includes:

  • levomenthol;
  • citric acid monohydrate;
  • oil of eucalyptus leaves;
  • purified water;
  • 96% ethanol;
  • polysorbate 80;
  • sodium saccharin;
  • sodium calcium edetate;
  • nitrogen.

The mechanism of action of hexoral is associated with a violation of oxidative processes occurring in the cell. That is why the remedy is so effective against most bacteria, pathogens of infectious diseases and inflammations, as well as fungi belonging to the genus Candida.

However, it must be borne in mind that the remedy is not able to help in the fight against Proteus and Pseudomonas aeruginosa. They are drug resistant.

The active substance of hexoral has an unexpressed analgesic effect. When the spray is applied to the throat, the components of the drug are evenly distributed over the mucous membrane, forming a film. The active substance is practically not absorbed into the systemic circulation. The tool remains active for several hours.

Pharmacological group

Hexoral is included in the 24.012 pharmacological group. It is a drug with antibacterial, antifungal action for local use in ENT practice and dentistry.

Indications for use

for adults

The list of indications for which the use of the drug is prescribed is very extensive. Geksoral use:

  • before and after surgery in the mouth and pharynx;
  • with, tonsillitis, glossitis,;
  • to eliminate bad breath;
  • in the treatment of severe purulent or febrile diseases of the oral cavity and pharynx;
  • with colds (used as an adjuvant);
  • with the appearance of autotrophic ulcers;
  • with fungal infections of the mouth and pharynx;
  • if infection of the alveoli occurs after tooth extraction;
  • as a hygienic remedy for general diseases;
  • with bleeding gums or gingivitis;
  • in the presence of collapsing tumors in the mouth and pharynx;
  • with periodontal diseases or the presence of their symptoms.

for kids

Pediatricians prescribe Hexoral Spray to children in the presence of infectious diseases in the mouth and pharynx. The tool helps fight:

  • fungal infections in the mouth;
  • colds;
  • , glossitis, gingivitis;
  • inflammation of the alveoli that appeared after the extraction of teeth;
  • purulent, accompanied by fever and intoxication;
  • and tonsillopharyngitis.

Geksoral does not adversely affect the health of the child during pregnancy or lactation. The drug is prescribed in the presence of diseases caused by bacteria. The use of the drug without prior consultation with a specialist is strongly discouraged.

Contraindications

Geksoral spray is suitable for almost all people suffering from infectious diseases of the nose and mouth. You should refuse to use the remedy if:

  • the child has not yet reached the age of 3;
  • a person has an individual intolerance to one of the components of the drug;
  • the patient has an individual hypersensitivity to the main active substance of the remedy.

Applications and doses

for adults

The drug is applied topically. A single dose is administered over 1-2 seconds. Hexoral is used 1-2 times a day after meals. Doctors advise spraying in the morning and evening. If necessary, the tool can be used more often. Hexetidine adheres to the mucous membrane. Thanks to this, the tool gives a lasting effect. The duration of the course of treatment is determined on an individual basis.

To spray the drug in the throat and treat the affected areas, you must perform the following steps:

  1. Place the aerosol tube into the appropriate hole in the top of the vial. To do this, you need to lightly press on it. Point the tip of the tube away from you.
  2. Holding the aerosol tube, direct it to the affected area of ​​the pharynx or oral cavity. The vial itself must be kept upright at all times.
  3. Enter the correct amount of the drug. To do this, press on the spray head for 1-2 seconds.

During the introduction of the drug you need to hold your breath.

for kids

The method of application and dosage for children are similar.


for pregnant women and during lactation

Taking Hexoral during pregnancy or lactation is possible after visiting a specialist.

Side effects

The drug has practically no side effects. However, a hypersensitivity reaction to the components of the agent is possible. If Geksoral is used for a long period of time, there may be a violation of taste.

Interaction with other drugs

Clinically significant interactions of Hexoral with other drugs are not described in the official instructions. It is better not to combine the drug with other medicines.

special instructions

For children, the remedy is prescribed when they stop resisting a foreign object in their mouth and can hold their breath. There must be no danger of uncontrolled swallowing. The official instructions indicate that the drug can be used from the moment the child reaches 3 years of age. However, some experts recommend shifting the age of starting the drug to 6 years.

Overdose

The drug is non-toxic if the dosage is strictly observed. When using the drug in large quantities, it may occur. Its appearance prevents the absorption of the drug. In practice, cases of poisoning with Hexoral have not been recorded.

If you have swallowed a large amount of the drug, you should consult a doctor. He will perform a gastric lavage, as well as carry out symptomatic therapy. Manipulations are performed within 2 hours from the moment of ingestion of the drug. Self-medication in this situation is prohibited.

Storage conditions

The product should be stored out of the reach of children at an air temperature not exceeding 25 degrees Celsius. The drug is suitable for use within 2 years from the date of manufacture. The use of a product with an expired expiration date is fraught with negative consequences. The specified period is relevant only if the person complied with the storage conditions of the drug.

Analogues

The drug has a number of cheaper analogues. By giving preference to them, a person will be able to save up to 70% of the cost of funds. Replace Hexoral capable of:

  1. . It is the closest analogue of the drug. The agent contains hexetedine and other substances in proportions similar or approximately equal to hexoral. The medicine is not recommended for children under 8 years of age.

No matter how hard we try, it happens extremely rarely that a special period in the life of a woman during the bearing of a child is not overshadowed by some kind of ailment at least once. Diseases of the oral cavity and larynx, perhaps, are included in the list of the most common, because the immune system is oppressed with the onset of pregnancy, and the body is defenseless against hordes of viruses, microbes and bacteria, starting from its gate - the oral cavity.

During pregnancy, dental diseases are often exacerbated, and the throat is also affected with colds and viral diseases. Hexoral can come to the rescue in such cases, but is it possible to use this drug now when you are carrying a new life under your heart?

Characteristics of the drug

Geksoral is able to eliminate pathogens that have settled in the oral cavity, envelop the mucous membranes, reduce pain, and also disinfects and deodorizes the oral cavity.

Hexoral is an antiseptic drug for topical use. Available in the form of tablets, spray for irrigation of the mouth and solution for gargling. Hexoral is prescribed for the treatment of dental and ENT diseases. Treatment of the oral mucosa with this agent leads to its complete sterilization, and therefore, the destruction of pathogenic bacteria. However, this also makes the mucosa defenseless, since its immunity is destroyed at the same time.

Nevertheless, Geksoral is widely used in practice as a local antiseptic, including in pregnant women. Often, doctors recommend it as a prophylactic against, as well as a first aid, especially for sore throats: both in the nascent and at the very beginning. Usually the dosage is one injection (if we are talking about a spray) for 1-2 seconds. The solution is used by adults in a volume of 10-15 ml undiluted: rinse the mouth for 1-2 minutes. Manipulations can be carried out twice a day - preferably in the morning and in the evening after meals. Important note: if the relief of the condition does not occur after three days, then you should stop using the drug and consult a doctor.

Is it safe to use Hexoral during pregnancy?

Doctors say that this drug has proven itself very well in the treatment of both children and adults. Yes, and patients note a good effect from these drugs and, as a rule, the absence of side effects. But what about the use of Hexoral during pregnancy?

There is no information about any effect of the drug on the course of pregnancy and fetal development. Relevant studies have not been conducted, so no one even knows whether it penetrates the placental barrier or not. This is definitely a minus, since you have absolutely no idea what to expect from such a treatment. In view of this, you should always consult with your doctor regarding the possibility of using Hexoral during pregnancy. And the doctor at the same time is obliged to carefully weigh all the possible risks and assess the need for an appointment.

We want to encourage you to carefully study the composition of any drug that you are going to use. Although there are as many contraindications for Hexoral as there are for other drugs, allergic reactions to its individual components are still possible. For example, benzocaine, which is part of Hexoral tablets, can also cause anaphylactic shock. And in young patients, benzocaine sometimes provokes the development of methemoglobinemia - this condition disappears with blue skin and mucous membranes, as well as the development of suffocation. An overdose of benzocaine depresses the brain. Suppression of the respiratory center causes a coma. Elevated amounts of the drug can provoke bradycardia and cardiac arrest. It is unlikely that you will drink so many pills to allow this in yourself. But the effect of benzocaine on the fetus has not been studied either ... So if an excess amount of the drug was accidentally taken, then it is necessary to rinse the stomach and provoke vomiting. You can additionally accept .

We also draw your attention to the fact that both the spray and the Hexoral rinse solution contain alcohol. It is this that for some doctors is often a deterrent when prescribing it to pregnant women. After all, such substances are contraindicated during the gestation period, especially in the early stages.

Instructions for use Hexoral:

- mode of application

Hexoral solution should be used undiluted for washing or rinsing the throat and mouth, or applied to the affected areas of the mucous membrane with a swab. The duration of the procedure is 0.5 minutes. For one procedure, 10-15 ml of solution should be used. Geksoral spray should be sprayed on the affected areas within 2 seconds. Hexoral is prescribed twice a day. The drug should be taken after meals.

- side effects

When using Hexoral, the development of allergic reactions, taste disturbances is possible. In cases of prolonged use of Hexoral, a change in the color of the teeth is possible.

- contraindications

Hexoral is contraindicated in case of individual hypersensitivity to the constituent drugs, children under three years of age (insufficient experience in pediatric practice).

- pregnancy

There is no data on the negative impact of Hexoral on the body of the fetus (child) or pregnant woman (nursing mother), however, due to the lack of data on the possibility of penetration of the components of the drug into breast milk or through the placental barrier, the use of the drug during lactation and pregnancy is possible only after a thorough analysis of the ratio "potential harm to the fetus - benefit to the mother."

- interaction with other drugs

Clinically significant interactions of Hexoral with other drugs have not been described.

- overdose

If a large amount of Hexoral is swallowed, nausea and vomiting may develop, and therefore significant absorption of the drug is not expected. Theoretically, swallowing the drug in large doses by a child can lead to ethanol poisoning. Overdose treatment: gastric lavage (within two hours after poisoning), symptomatic therapy.

Specially for- Elena Kichak

From Guest

Yes, where has it been seen that they experimented, it is impossible, etc. ... Better folk recipes .... Another nonsense of a narrow-minded person. If the doctor prescribes, then it is necessary. My friend used to walk like this - she was saving her pregnancy. Saved. Having become pregnant, she treated a sore throat with folk recipes, she got bronchitis in the end. In the first trimester, she was treated with antibiotics for bronchitis in the first trimester, and secretly threw away the pills. As a result, with bleeding, detachment and hematoma, they were transferred to preservation. Almost cleaned - there was a lot of blood. Two months on sick leave, barely saved. Two months of fear and tears. They said that a strong cough and bronchitis provoked such a situation. Here also are treated... a camomile. If a doctor prescribes and there are indications, then no one asks you to talk about the dangers of cosmic radiation and chemicals. It's just a throat spray, not a weapon of mass destruction...

The main active ingredients of hexoral tablets are chlorhexidine and benzocaine. Some people have an individual intolerance to benzocaine. In such cases, allergic reactions are likely to occur, including anaphylactic shock. In addition, benzocaine sometimes provokes the development methemoglobinemia in small patients. This condition passes with blue integuments and mucous membranes, as well as the development of suffocation. Therefore, before starting treatment of a child with Hexoral tablets, a pediatrician should be consulted.

The drug should be used very carefully so that an overdose does not occur. An overdose of benzocaine may cause dizziness, shortness of breath, methemoglobinemia, and cyanosis. It is necessary: ​​symptomatic treatment and the introduction of intravenous methylene blue.

The number of days of using Hexoral is determined only by the attending doctor.
The drug cannot cause any serious conditions if used according to the doctor's prescription and the dosage indicated in the annotation to the drug. If an overdose is allowed, you should consult a doctor.

If an excess amount of the drug was accidentally taken, it is necessary to rinse the stomach and provoke vomiting. You can take activated charcoal. If hypoxic manifestations are observed, artificial respiration should be performed using an oxygen bag.

The drug has the ability to cleanse the mucous membrane of microbes, including fungi, anesthetize, stop bleeding, and also cover the mucous membrane with a protective film. The duration of action of the Hexoral solution is up to twelve hours. The solution is prescribed as a component of the treatment of acute respiratory and viral diseases, with fungal lesions of the mucous membrane, bacterial infections, tonsillitis, tonsillitis, alveolitis, candidiasis of the oral mucosa, bleeding gums, in preparation for surgical interventions and in the postoperative period.

Do not prescribe the drug for individual intolerance to the components of the drug.
Treat the affected areas with a cotton swab or by rinsing the mouth or throat. For a one-time rinse, take ten to fifteen milliliters of Hexoral solution and rinse for thirty seconds. The liquid is not allowed to be taken internally.

Store the product at room temperature in a dark place. Do not freeze the solution. The solution is sold in plastic bottles of two hundred milliliters.

Treatment of stomatitis is a complex problem. First of all, it is necessary to find the cause of the disease. But in any case, we are always talking about the presence of pathogenic microflora in the oral cavity. Therefore, it will be mandatory for any form of the disease to treat the affected areas with antiseptic preparations.

One of the most effective drugs is hexoral. Moreover, hexoral can be used even with a herpetic or fungal origin of the disease. Using Hexoral is very simple: you need to spray the affected surfaces twice a day after meals or rinse your mouth with liquid. The duration of treatment depends on the condition of the patient. In addition, the doctor will definitely prescribe drugs to strengthen the immune system, vitamins, especially ascorbic acid. Before recovery, it is advisable to give up hot, spicy, sour and too sweet food, which additionally irritates the affected areas.

It is forbidden to use tablets for wounds and ulcers of the oral cavity or pharynx, in the treatment of babies under four years of age, as well as for individual intolerance to the components of the drug.
Long-term use of Hexoral Tabs can lead to discoloration of the tooth enamel and tongue, as well as changes in taste sensations and loss of sensation on the tongue. With extreme caution and after consulting a pediatrician, it can be used in the treatment of children.

Clove oil - another component of Hexoral - is an unsurpassed remedy for tissue regeneration and the treatment of inflammatory processes in the respiratory system and throat. It is also used to prevent acute respiratory and viral diseases, since clove oil effectively fights microorganisms. It is most commonly used for outdoor applications. But there are recipes for using clove oil to strengthen the general condition of the body, normalize blood pressure, and even improve memory. For these purposes, two drops of oil are dripped onto one teaspoon of honey and consumed for fifteen days.

Latin name: Hexetidine
ATX code: A01AB12
Active substance: Hexetidine
Manufacturer: FAMAR ORLEANS, France
Pharmacy leave condition: Without recipe

Hexoral is a drug that has analgesic, antimicrobial and disinfectant effects. It is used as part of complex therapy or as an independent remedy for the treatment of diseases of the oropharynx.

It has a wide range of effects and has its effect on bacteria, some types of fungi and protozoa. It is used in patients of various ages, including children after 3 years.

Indications for use

Geksoral can be used to treat various diseases of the throat. This tool is indicated in the following situations:

  1. Fungal infections of the mouth, throat and larynx
  2. Treatment of inflammatory processes of the throat and oral cavity, which includes gingivitis, stomatitis, tonsillitis, etc. Hexoral with angina has a complex effect and eliminates the symptoms of the disease
  3. To prevent the development of secondary infection during surgical interventions. The drug can be prescribed both before surgery and in the postoperative period
  4. Elimination and treatment of bad breath in case of tumor processes or dental pathology
  5. With increased bleeding of the gums, it can be used as a local hemostatic agent.

The composition of the drug

The active substance is hexetidine. Auxiliary components of the drug: eucalyptus, anise, clove and peppermint oil, ethanol, levomenthol, methyl salicylate, citric acid, sodium saccharinate, purified water, etc.

Such a composition allows it to have a complex effect and eliminate not only the cause of the disease (bacteria, etc.), but also effectively deal with the main symptoms of the disease (pain, burning and discomfort in the throat).

Hexoral is not an antibiotic. It is a topical antiseptic and cannot replace antibiotic treatment when needed.

Medicinal properties

Geksoral shows its antibacterial properties due to the active ingredient hexetidine, which contributes to the destruction of the cell wall of microorganisms. In addition, it can destroy the formation of fungal membranes, which causes its antimycotic effect.

The essential oils included in the preparation have a deodorizing and anti-inflammatory effect. Levomenthol stimulates mucosal receptors and provides a distracting, cooling and analgesic effect.

When used locally, the drug is practically not absorbed and does not enter the systemic circulation. Insignificant concentrations of the drug can be detected within 3 days after a single use.

Spray Geksoral

Price: 320 rubles

Hexoral spray 0.2%. 100 ml of aerosol contains 0.2 g of hexetidine. The box contains an aerosol can and a spray nozzle. The drug has a pleasant mint smell.

Dosage and administration

Hexoral in the form of an aerosol is used after meals. For a child over 6 years old and an adult, the dosage is 1 irrigation 2-3 times a day. A child from 3 to 6 years old can be given medicine only after consulting with the attending doctor. For irrigation, you need to put a special nozzle on the balloon and spray it into your mouth for a few seconds. In this case, the patient is advised to hold his breath. The course of treatment is determined by the doctor. According to the instructions, the drug is not recommended to be used for more than 10 days in order to avoid the development of drug resistance.

Hexoral solution

Price: 280 rubles

Hexoral solution 0.1%. 100 ml of Hexoral solution contains 0.1 g of hexetidine. In a transparent bottle of 200 ml of a pink solution, it has a pleasant mint smell.

Dosage and administration

Hexoral in the form of a solution for gargling. It can be given to a child after 3 years of age and to an adult at a dosage of 15-20 ml of undiluted gargle solution. The frequency of use is 2 times a day, unless otherwise prescribed by the doctor. Use only as a rinse, the solution must not be swallowed.

Tablets for resorption Geksoral Tabs

The cost of this tool is in the range of 170-180 rubles for 20 pieces.

There are lozenges under this trade name Geksoral Tabs. These tablets differ in composition: they include chlorhexidine (local antiseptic) and benzocaine (local anesthetic). There are several types of these tablets: with lemon, orange, mint or blackcurrant flavor. The carton box contains two blisters of 10 tablets each.

Dosage and administration

Lozenges. Adults and children over 12 years of age 1 tablet every 2 hours. A child from 4 to 12 years old is allowed to use 4 tablets per day, provided that he knows how to dissolve them, and not swallow or chew. If not, then these tablets are not used. In children under one year, the medicine is not used.

During pregnancy and breastfeeding

The drug is practically not absorbed by the mucous membrane of the throat, but there are no clinically verified data on the use of this drug in pregnant and lactating women. Treatment is carried out if the benefit to the mother outweighs the potential risk to the unborn baby.
Contraindications

Geksoral for children in any form of release is contraindicated under 3 years of age due to insufficient clinical data on its use in this age group.

In babies up to a year, it is absolutely contraindicated in any form. You can not lubricate them with a pacifier or apply even drop by drop to the oral mucosa.

Contraindications

The drug is contraindicated in case of allergy or individual intolerance to any of the components of the drug.

Precautionary measures

Aerosol is used with caution in children under 6 years of age. The drug does not affect the ability to drive and control moving mechanisms, but the solution contains a small amount of alcohol, so it is better to rinse half an hour before driving.

If treatment is ineffective within 4-5 days or the patient's condition worsens, a systemic antibiotic is prescribed, after consulting a specialist.
Cross-drug interactions

There are no described clinically significant drug interactions of this drug with other drugs.

Side effects

There is a possibility of developing allergic reactions, as well as a violation of taste sensitivity, which disappear after discontinuation of the drug. With prolonged use, a change in the color of the teeth is observed.

Overdose

There are no data on its toxicity at the indicated doses. If you swallow a large amount of Hexoral solution, you can cause signs of alcohol intoxication.

Terms and conditions of storage

Store in places inaccessible to children. Shelf life within 2 years.

Analogues

Hexaspray

Bowchar-Recordati Laboratory, USA
Price: 260-270 rub

The active substance is biclotymol. Hexaspray has an antibacterial, anti-inflammatory and analgesic effect on the throat. If the reception is ineffective within 3-4 days, a systemic antibiotic is prescribed.

Pros:

  • You can use Hexaspray 3-4 times a day, regardless of food intake.
  • Allowed during pregnancy and lactation.

Minuses:

  • Child only from 6 years old
  • Leaves a bitter taste in the mouth.

Stopangin

IVEX Pharmaceuticals, Czech Republic
Price: 250-270 rub

Types of medicine: spray and solution for gargling. The active substance is hexatidine, auxiliary components: mint, clove, anise, orange oil, etc. Stopangin solution is used undiluted in 10-15 ml for each rinse, it is better to use it before meals or between meals.

Pros:

  • Contains a large complex of essential oils
  • A change in taste sensations is rare.

Minuses:

  • Stopangin is contraindicated in a child under 6 years of age and in the 1st trimester of pregnancy.
  • Do not use for atrophic processes in the pharynx.

The original drug hexoral (active ingredient - hexetidine) is a local antiseptic from the world famous transnational pharmaceutical company Pfizer. This drug is widely used in otolaryngology and dentistry, most often used to treat inflammatory diseases of the pharynx - pharyngitis, which are acute and chronic, and sometimes spread to the nasal (nasopharyngitis) and oral (mesopharyngitis) part of the mucous membrane of the upper respiratory tract. In acute pharyngitis, patients are prescribed a sparing diet that provides for minimal exposure to the affected mucous membrane, alkaline rinses, as well as local antiseptics and antibacterial drugs. Treatment is directed, for the most part, to reduce inflammation and relieve sore throat (so-called symptomatic therapy). Given the fact that most pharyngitis is based on a viral infection, the appointment of antibacterial drugs may be inappropriate. Destroying "both their own and others" (read: pathogenic and non-pathogenic microorganisms), they worsen the patient's immune status, increase the risk of recurrence of the disease and condone the emergence of allergies. At the same time, the severity of negative adverse reactions of inadequate antibiotic therapy often further exacerbates the course of the disease of the pharynx. For this reason, local antiseptics are increasingly prescribed for the treatment of pharyngitis, one of which is hexoral. This drug is available in two dosage forms: an aerosol and a rinse solution. The antimicrobial effect of hexoral is due to the inhibition of oxidative reactions in the metabolism of bacterial cells (the active substance of the drug hexetidine is an antagonist of thiamine, better known as vitamin B1). The spectrum of antibacterial and antimycotic action of hexoral is quite wide: it covers, in particular, gram-positive bacteria and fungi of the genus Candida. The drug is also effective in the treatment of infections caused by Proteus and Pseudomonas aeruginosa.

At a concentration of 100 mg / ml, hexoral suppresses most of the bacterial strains sensitive to it. Cases of development of resistance to hexatidine in medical practice were not observed. The drug has a weak local anesthetic effect. Hexetidine is endowed with an outstanding ability to adhere to the mucous membrane, while being practically absorbed. After applying a single dose of hexoral, traces of the active substance are found on the mucous membranes for 65 hours.

Solution dosing regimen: adults and children from 3 years of age use Hexoral solution for rinsing the oropharynx in an amount of 15 ml for at least 30 seconds. The solution is used undiluted. Multiplicity of application - 2 times a day, as a rule - after waking up and before bedtime. Hexoral is well tolerated by patients even with more frequent use. The duration of the drug course is determined by the doctor. Geksoral is allowed to be used only for rinsing the mouth and throat: the solution cannot be swallowed. Another way to use a solution of hexoral is to apply it to the affected areas of the oral cavity with a swab. A solution of hexoral for topical use is allowed to be used only if the patient has the opportunity to spit it out after rinsing. Dosing regimen of hexoral aerosol: adults and children from 3 years old - one injection 2 times a day (unless otherwise indicated), preferably after meals, in the morning and evening. A single dose is sprayed into the mouth or throat for 1-2 seconds. Before injection, it is necessary to put a spray nozzle on an aerosol can, and then direct it to the affected area of ​​the mucous membrane. During spraying, the bottle should be kept in an upright position, as shown in the figure in the instructions for use. During the introduction of the aerosol, it is recommended not to breathe.

Pharmacology

Antiseptic.

The antimicrobial effect of Hexoral ® is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist). The drug has a wide spectrum of antibacterial and antifungal activity, in particular against gram-positive bacteria and fungi of the genus Candida, but Hexoral ® can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg / ml, the drug suppresses most strains of bacteria. The development of resistance was not observed. Hexetidine has a weak anesthetic effect on the mucous membrane.

Pharmacokinetics

Hexetidine adheres very well to the mucous membrane and is practically not absorbed. After a single application of the drug, traces of the active substance are found on the gum mucosa for 65 hours. In plaques on the teeth, active concentrations remain for 10-14 hours after application.

Release form

Solution for topical use 0.1% in the form of a clear red liquid with a mint odor.

Excipients: ethanol 96% - 4.3333 g, polysorbate 60 - 0.7 g, peppermint oil - 0.064 g, anise oil - 0.0392 g, citric acid monohydrate - 0.0418 g, sodium saccharinate - 0.022 g, levomenthol - 0.0186 g, methyl salicylate - 0.0186 g, clove oil - 0.0084 g, eucalyptus oil - 0.0011 g, azorubine 85% (E122) - 0.0023 g, purified water - up to 100 ml.

200 ml - colorless glass bottles (type III) (1) complete with a measuring cup - packs of cardboard.

Dosage

Adults and children over 3 years of age: apply topically in the form of mouth and throat rinses for at least 30 seconds with 15 ml of an undiluted solution. Unless otherwise indicated, apply 2 times / day, preferably in the morning and evening.

Hexetidine adheres to the mucous membrane and thus gives a lasting effect. In this regard, the drug should be used after meals. Geksoral ® is also safe with more frequent use.

Geksoral ® topical solution can only be used for rinsing the mouth and throat. The solution must not be swallowed.

For rinsing, always use an undiluted solution.

In the treatment of diseases of the oral cavity, the drug can also be applied with a swab.

The duration of treatment is determined by the doctor.

Do not use in children under 3 years of age.

Overdose

Hexetidine at the indicated dosage is non-toxic.

Symptoms: Swallowing large amounts of the drug leads to vomiting, so significant absorption is not expected. Cases of alcohol poisoning in case of overdose have not been described. Acute alcohol poisoning is very unlikely, but theoretically possible if a large dose of the drug is swallowed by a young child.

Treatment: gastric lavage is necessary within 2 hours after swallowing an excess dose. Carrying out symptomatic therapy, as with alcohol intoxication. In any case of overdose, the patient should immediately consult a doctor.

Interaction

Drug interaction of the drug Geksoral ® is not described.

Side effects

In some cases: hypersensitivity reactions to the drug.

With prolonged use: taste disturbance is possible.

Indications

  • inflammatory and infectious diseases of the oral cavity and pharynx;
  • in the complex treatment of severe febrile or purulent diseases of the oral cavity and pharynx, requiring the appointment of antibiotics and sulfonamides, tonsillitis;
  • tonsillitis (including tonsillitis with lesions of the lateral ridges, Plaut-Vincent's tonsillitis);
  • pharyngitis;
  • gingivitis and bleeding gums;
  • periodontopathy (periodontal diseases and their symptoms);
  • stomatitis (inflammation of the oral mucosa), glossitis (inflammation of the tongue), aphthous ulcers (painful inflammation with superficial tissue defects) to prevent superinfections;
  • infection of the alveoli (holes of the teeth) after the extraction of teeth;
  • fungal infections of the oral cavity and pharynx, especially candidal stomatitis (thrush);
  • before and after operations in the oral cavity and pharynx;
  • additional oral hygiene for general diseases;
  • elimination of bad breath, especially in the case of collapsing tumors of the oral cavity and pharynx;
  • adjuvant in the treatment of colds.

Contraindications

  • children's age up to 3 years;
  • hypersensitivity to the components of the drug.

Application features

Use during pregnancy and lactation

There is no information about any undesirable effects when using the drug Geksoral ® during pregnancy and during breastfeeding. However, before prescribing Hexoral® to pregnant or lactating women, the physician should carefully weigh the expected benefits and risks of treatment, given the lack of sufficient data on the penetration of the drug through the placental barrier and excretion in breast milk.

Use in children

Contraindicated in children under the age of 3 years.

special instructions

There are no special instructions.

Geksoral ® topical solution can be used for rinsing the mouth and throat only if the patient can spit out the solution after rinsing.

Hexoral ® topical solution contains ethanol 96% (4.33 g/100 ml solution).

Pediatric use

In children, the drug can be used from an age when there is no danger of uncontrolled swallowing when using the solution.