How long can open drops of otipax be stored. How long can Otipax be stored after opening the vial. Indications for use

Otipax is prescribed for acute otitis media children and adults. This combined drug is applied topically, it has an anti-inflammatory and anesthetic effect. The course of treatment for otitis media and other inflammatory diseases of the ears is usually no more than 10 days, and after that, many patients have the question of how long Otipax can be stored after opening. The instructions indicate that this period should not exceed six months, but it all depends on the storage conditions.

Description of the drug

Otipax is a drug for local application. The active substances of this medication are phenazone and lidocaine. The drug is produced in tinted glass bottles, which are equipped with a dropper. Each bottle is packed in a cardboard box together with instructions for use. The shelf life of a medicinal product with unopened packaging is 5 years. After opening, the shelf life is significantly reduced and, according to the instructions, is 6 months.

Otipax is prescribed for a number of ear diseases inflammatory nature, which include:

• acute otitis media;
• otitis, which arose as a complication respiratory infection or flu;
• with otitis media of barotraumatic origin;
• with post-traumatic otitis and inflammation of the ears after the removal of foreign objects.

The drug is instilled into the ear passages in the amount of 4 drops, up to 3 times a day. Treatment should be continued for as many days as prescribed by the doctor. If this information was not indicated, then continue to drip the sore ear until all symptoms disappear and a couple more days after that to consolidate the effect.

What to look out for

How to properly store the drug

The shelf life of the drug directly depends on the conditions under which it is stored. Ear drops should be stored at room temperature, which does not exceed 25 degrees. The best option will be stored on the doors of the refrigerator or in any cool dark place.

After opening the bottle, a special cap is screwed onto the dropper, which is attached. The bottle is placed in the original box along with instructions. It should be borne in mind that a bottle with a wound dropper does not fit well in a cardboard box, so it is preferable to place the drug in a plastic bag.

During the entire period of treatment, the drug is also stored in the refrigerator. Before use, the bottle is warmed in the hands to room temperature.

What happens if you drip expired drops

The shelf life of Otipax after opening is only six months, and then, under proper storage conditions. However, judging by the reviews, you can be treated with those drops that were discovered more than six months ago. When the vial is opened, sterility is violated, but the effectiveness of the drug remains up to a year after opening, but only if stored properly.

If there is no fresh drug at hand, then it is quite possible to drip a sore ear with Otipax, which is open in the refrigerator. With a whole eardrum the drug is not absorbed into the bloodstream, it has only a local effect and, therefore, will not bring harm. Applying long-open drops. Two scenarios can be expected:

1. Drops will not help at all, but they will not bring harm either.
2. A slightly expired drug will remove ear pain and inflammation, no worse than just bought.

The manufacturer produces Otipax in 15 ml bottles. This amount of the drug is definitely enough for more than one treatment of otitis media. After the need for this drug disappears, it is simply put in the refrigerator and stored in case of acute pain in the ears.

Do not use Otipax drops when inflammatory diseases ears in such cases:

• If the original packaging of the medicinal product is broken.
• If the medicine was bought in a place not intended for the sale of medicines.
• If storage conditions have been violated medicinal product. For example, it was stored at too high temperature or has been frozen.
• Do not use the medicine if the color is changed or if there is a sharp, unpleasant odor.
• You should not bury your ears with Otipax if you are allergic to lidocaine or other components in the drug.

You can start treatment with Otipax only on the advice of a doctor. It is permissible as a first aid for a sharp pain to drip one-time ears, but then the patient must be examined by a doctor.

Otipax should be in every home first aid kit. Such ear drops effectively remove sharp pain with otitis, which are caused by various reasons. Although the instructions say that the drug can be used for no more than six months after opening the vial, it can be used for a longer time, subject to storage conditions.

ATX

S02DA30 Analgesics and anesthetics in combination

Pharmacological groups

• Local anesthetics in combinations
• NSAIDs - Pyrazolones in combinations

Composition and form of release

100 g ear drops contain phenazone 4 g and lidocaine hydrochloride 1 g, as well as sodium thiosulfate, alcohol 95%, glycerin in equal proportions up to 100 g; in vials of 16 g, in cardboard box 1 vial.

pharmachologic effect

Pharmacological effects - antiseptic, local anesthetic, anti-inflammatory.

Phenazone blocks cyclooxygenase and inhibits the biosynthesis of "anti-inflammatory" PGs. Lidocaine, due to antagonism with sodium and calcium ions at the level of the nerve fiber membrane, disrupts the perception and conduction of a pain impulse.

Indications for Otipax®

Otitis media: acute, post-influenza, barotraumatic, etc.

Contraindications

hypersensitivity, mechanical damage eardrum, allergic reaction to lidocaine.

Side effects

Allergic reactions.

Dosage and administration

Buried in the outer ear canal 4 drops 2-3 times a day for 10 days (no more).

Storage conditions of the drug Otipaks®

At temperatures below 30 °C (do not freeze).

Keep out of the reach of children.

Shelf life of Otipax®

Do not use after the expiry date stated on the packaging.

Otipax is a drug that is used in otolaryngology to treat inflammation of the ears. It can be attributed to combined group drugs. The composition of the drug as an active ingredient includes lidocaine hydrochloride and phenazone, which quickly expire after opening.

The drug is also classified as a group B drug. Based on this, you can apply all the conditions that belong to this group, if there are no contraindications.

Before using the medication, be sure to consult your doctor.

Properties of the drug

Otipax has a strong anti-inflammatory and local anesthetic effect, and it also has antiseptic property, as it reduces pain and relieves inflammation of the eardrum. Otipax begins its effect within 5-10 minutes after application. Within half an hour, the pain syndrome disappears completely.

How to use the drug correctly

• Acute otitis media.
• With otitis, which occurs after having been ill with the flu.
• Paratraumatic otitis.

Instructions for use

It is necessary to instill the auricle with the drug externally, 4 drops 3 times a day.

Treatment must be carried out in courses. One course is not more than 10 days. Before using the drug, you need to remove the aluminum coating from the cap by pulling on a specially made tongue.

Applying force, we put the pipette on the bottle. Then you need to open the cap white color. Shake the bottle before use.

By lightly pressing the center of the pipette, you need to drip into the ear. At the end of the use, the pipette is tightly closed with a white cap, and the bottle is hidden in the packaging from sunlight. Adhering to all instructions, an overdose is excluded.

Presence of side effects

As a side effect, an allergic reaction to the components of the drug can act. Symptoms may include itching, redness, and irritation.
If you experience these symptoms, after using Otipax, you should immediately contact your doctor and stop using this drug.

Contraindications for use

It is not recommended to use Otipax after the eardrum has been infected or injured. Also, you can not use the drug for those who have an allergic reaction to the elements included in the drug, in particular to lidocaine.

Pregnancy and lactation period

Consult your doctor before using this medicine during pregnancy or lactation.

Reaction to use with other drugs

Before using Otipax with other medicines, you should consult your doctor. During the research on the drug, it was determined that the components of the drug do not enter into chemical reactions with other medicines.

Advantages

The drug Otipax is approved for use in the treatment of diseases of the auricle in an infant.

This drug is available in vials with different weights. Each bottle has its own shelf life before and after opening.

A dosage of 40 ml is stored at room temperature, no more than five years. It must be kept out of the reach of children and out of direct contact with sun rays. After the bottle is opened, the drug can be stored for no more than six months.

When the expiration date has expired, the drug is discarded and not recommended for further use. A bottle with a dosage of 15 ml is stored no more than three years from the date of manufacture. It is also kept out of the reach of children and away from sun exposure.

Also, the temperature should not be allowed to rise, within the range of 25 - 300C. After opening the package, the medicinal product is allowed to be stored for no more than a month. It is not allowed to use Otipax after the expiration date, since the manufacturer cannot be held responsible for its effect on the body.

Under what conditions can you buy Otipax

This drug is sold in all pharmacies without a prescription.

This medication includes the following components:

• Phenazon.
• Lidocaine hydrochloride.
• sodium thiosulfate.
• Ethanol.
• Distilled water.
• Glycerin suspension.

The first two components are the main ones and make up the drug by 34%. For example, for 16 grams of funds goes 0.66 gr. phenazone and 1.7 lidocaine hydrochloride.

Produced in bottles dark color from glass.

Also included is a flexible dropper or pipette. The package contains one bottle. The kit includes instructions for the use of the drug.

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1 g of the drug contains phenazole (40 mg) and lidocaine hydrochloride (10 mg).

Sodium thiosulfate (1 mg), glycerol (709 mg), ethanol (221.8 mg), water (18.2 mg) are auxiliary components.

Release form

Drops in a bottle with a dropper 15 ml. Clear, colorless or yellowish solution with an alcoholic odor.

pharmachologic effect

Anti-inflammatory, analgesic, antiseptic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

combination drug with local anesthetic And anti-inflammatory action .

Phenazone - non-steroidal anti-inflammatory agent, analgesic with anti-inflammatory action. It blocks cyclooxygenase and inhibits the synthesis of prostaglandins.

Lidocaine - local anesthetic. Violates the conduction of a pain impulse due to antagonism with sodium and calcium of the nerve fiber membrane. A successful combination of two active substances contributes to a rapid analgesic effect, increases its intensity and duration. The drug stimulates the liquefaction of mucus and its removal from the middle ear cavity through eustachian tube and eardrum.

Pharmacokinetics

When the integrity of the eardrum is preserved, it does not penetrate the body.

Indications for use

• otitis media in stage catarrh ;
• otitis barotraumatic ;
• otitis after the flu.

Contraindications

• allergic reaction to components;
• violation of the integrity of the eardrum.

Side effects

• irritation of the ear canal;
• allergic reactions.

Ear drops Otipaks, instructions for use (Method and dosage)

Drops in the ear are instilled 2-3 times a day, 3-4 drops. The dosage for children will be indicated below in a special section. Before use, the solution must be warmed by holding it between the palms. The course of treatment is not more than 10 days.

The instructions for use of Otipax contain a warning that the drug is not used for violation of the integrity of the eardrum .

Overdose

No cases of overdose have been reported.

Interaction

There are no data on interactions with other drugs.

Terms of sale

Released without a prescription.

Storage conditions

Storage temperature - up to 30°C. Keep out of the reach of children.

Best before date

5 years. Shelf life after opening the vial - 6 months.

Otipax for children

IN childhood from the nasopharynx, the infection often enters the middle ear and causes otitis media. The safest drug for catarrhal otitis is Otipax for children, which has anti-inflammatory and analgesic effects.

In addition to catarrhal otitis, it is used for ear congestion ( eustachian ) in children, with otitis externa, some forms purulent otitis media and after extraction foreign bodies. They are used in children to relieve pain in the preperforative stage. otitis media starting from infancy.

Instructions for Otipax for children

Pre-drops are heated to 38-40 °C. It is better to bury the drops on a turunda made of cotton wool or gauze inserted into the ear. For children up to a year, 1-2 drops are used, from 1 to 2 years - 3 drops, for children preschool age and schoolchildren - 4 drops 3 times a day.

After instillation, it is necessary to hermetically close the ear canal with cotton wool lubricated with petroleum jelly - the drug will not evaporate and its effectiveness will be higher. A single use of the drug gives a short-term effect, so its course use is necessary. The anti-inflammatory effect is noted on the 2-3rd day.

Otipax during pregnancy

The drug is not absorbed into the blood and does not have a systemic effect, so Otipax can be used during pregnancy, provided that the eardrum is not damaged.

Otipax's analogs

Coincidence in the ATX code of the 4th level:

The price of Otipax analogs differs significantly. So, Otirelax 15 ml can be purchased for 100-200 rubles, Sofradex 5 ml for 190-500 rubles. Price Otinuma 10 ml 170-300 rubles, Anaurana 25 ml 270-470 rub.

Which is better: Otipax or Otinum?

It has an anti-inflammatory and moderate local anesthetic effect. The difference between the two drugs is in the active substance: Otinum contains choline salicylate - derivative salicylic acid, and there is no anesthetic, so the analgesic effect is not so pronounced. If it enters the middle ear, ototoxicity occurs. It is used in children from 1 year. Manufacturer ICN Polfa Rzeszow(Poland)

Anauran or Otipax - which is better?

Contains local anesthetic lidocaine and antibiotics polymyxin And . In terms of anti-inflammatory effect, this drug is stronger, but the presence of ototoxic antibiotics is a contraindication to their use in perforation of the eardrum. The drug is effective in otitis externa and otitis media until perforation occurs. Has no age restrictions. Manufacturer Zambon S.P.A.(Italy).

Sofradex or Otipax - which is better?

Sofradex contains two antibiotics (and gramicidin ) and glucocorticoid dexamethasone . By the strength of the anti-inflammatory action, it surpasses the described drug. Glucocorticoids are not ototoxic, while antibiotics are ototoxic. Drops are intended for the treatment of otitis without violating the integrity of the eardrum. Of course, only a doctor can determine this upon examination, and, accordingly, recommend this or that drug. Used in children from 7 years. Manufacturer Aventis Pharma(India).

Otirelax or Otipax - which is better?

Otirelax - a structural analogue of Otipax (their composition is the same) and the action too. The difference is that the latter is original drug, and Otirelax is a generic produced by Rompharm Company S.R.L.(Romania).

Otofa or Otipax - which is better?

It combines a pronounced antibacterial effect and the absence of ototoxic action. Active substance - rifamycin , which is not an ototoxic antibiotic and these drops can be used in the perforative stage. In this plan this drug has an advantage, since all the above drugs (Sofradex, Otinum, Otipax, Anauran) have the main contraindication - perforation of the eardrum. Manufacturer Bouchard-Recordati Laboratory(France).

One of the most effective drugs for the treatment of otitis media, ear drops of the French manufacturer Otipax are considered, which relieve pain and inflammation. The medicine is so safe that it can be bought at a pharmacy without a prescription, and doctors recommend it to pregnant and lactating women. Drops Otipaks can not be used only in case of rupture of the eardrum (this happens when pus with otitis media breaks through it to get out), as well as excessive sensitivity to the components of the drug.

It is not difficult to recognize otitis media: when the disease is felt, stuffiness in the ears is felt, the hearing organs begin to hurt, the pain often has a pulsating or aching character and radiates to different parts of the head, as a result of which hearing deteriorates. With otitis media, body temperature often rises to 39 °, there is general weakness, dizziness, worsening appetite.

Since these symptoms may well indicate the presence of another disease, you should not self-medicate, and you should definitely consult a doctor who will carefully examine the ear, prescribe an additional examination and determine the treatment.

Otipax, which is an anti-inflammatory, analgesic antiseptic, is prescribed for any form of inflammation of the middle ear, otitis, if the pus has not broken through the eardrum and has not come out. It is considered one of the most effective drugs at a very reasonable cost - from three to five dollars.

Outwardly, it is a clear, colorless or yellowish solution with the smell of alcohol, which is in a dark glass bottle. According to the instructions, the active ingredients of the drug are lidocaine, phenazole and auxiliary components - sodium thiosulfate, glycerol, water, ethanol. One of the components of the drug is able to give a positive reaction to doping control, so it is better for athletes not to use the drug. Active ingredients by themselves, they have a very good effect on the foci of inflammation, their combination enhances the effect.

Phenazol is an anti-inflammatory and analgesic, which in former times was used as an independent medicine, and gauze or cotton swabs were moistened in it to stop bleeding. Another component of the drug, lidocaine, is considered the strongest pain reliever: the drug affects nerve fibers and inhibits the movement of nerve impulses.

Auxiliary substances also actively contribute to the fight against otitis and successfully relieve pain from the ear. For example, sodium thiosulfate has an anti-inflammatory, antitoxic effect on the ears, and also slows down possible appearance allergic reactions.

The influence of the drug

According to the instructions, according to its properties, Otipax is a medicine. local action: affects only the part of the body with which it comes into contact (on the ear). If the tympanic membrane is not damaged, the components of the drug do not enter the bloodstream, and therefore do not have side effects if the person is not allergic to phenazole, lidocaine or another component.

Before using ear drops, an otolaryngologist should still be consulted, otherwise, if an allergic reaction occurs, itching or swelling in the ear area may appear. The doctor should carefully examine the ear to check if there is a rupture or tear in the eardrum, because of which the use of the drug threatens to increase inflammation of the middle ear, itching, redness and other complications (which there is a corresponding warning in the instructions).

Depending on the state of development of the disease, as well as individual sensitivity to the components of the drug, some people feel the disappearance of pain and stuffiness in the ears as early as fifteen minutes after the ear drops have been instilled. Others argue that Otipax is not an instant remedy, and in some cases it is necessary to wait two or three days for the pain to go away. But after these days, pain and inflammation almost always disappear completely, swelling significantly decreases, redness disappears.

Despite all their positive characteristics, Otipax itself does not cure the disease, and therefore is more used as aid in the treatment of otitis media.

Therefore, the drug should be used in parallel with antibiotics. The advantages of ear drops are that Otipax can be used in parallel with other painkillers, antibiotics, anti-inflammatory drugs, which makes it possible to make the treatment more successful.


Judging by the reviews, Otipax can be used with a sharp change atmospheric pressure, for example, when flying in an airplane, due to the analgesic properties of the components that make up the drug, the drug successfully relieves pain and ear congestion.

Application

For an adult, according to the instructions, three to four drops are prescribed in each ear two or three times a day, for children - four drops twice a day. It is impossible to drip for more than ten days, if congestion after using the drug and other medicines has not passed, the method of treatment should be reviewed. Despite the fact that the shelf life of the medicine is five years, after opening it is no more than six months.

If, after the expiration date of Otipax, drops are inadvertently dropped into the ear (for example, you can look at the expiration date in the instructions and not pay attention that after opening its shelf life is much less), you should not worry too much. The components will not negatively affect the ears, but they will not bring any benefit either, because of which otitis media can intensify, which will increase pain and a feeling of stuffy ears.

According to the instructions, Otipax should be stored in a dark place at a temperature not exceeding 30 °, and it is also undesirable to store the medicine in the refrigerator. Before use, either warm the bottle in your hand, or, by typing it into a special dropper, which is sold with the product and is very convenient to use, turn it over. When the medicine is in a rubber tube, lower it into water, the temperature of which is about 37 °, hold it for a while.

Before dripping the product, the auricle should be washed from contamination with hydrogen peroxide: a few slightly warmed drops should be dropped into the ear and lie down for about five minutes, after which, after making a flagellum out of cotton, remove the liquid and tilt your head in the opposite direction.

When burying the medicine in the ears, the head must be held horizontally so that it does not leak out of the ear.

You need to drip not directly into the auditory canal, but a little from the side to allow the air to freely leave the ear canal: otherwise, a plug will form between the product and the eardrum, and the desired effect will not work. You can apply drops in a slightly different way: make a cotton flagellum, moisten it in warm medicine, squeeze it well and insert it into your ears.

To prevent Otipax from leaking out of the ears, a cotton swab should be placed in the auricle (it will not only retain the liquid, but also create a thermal effect). If congestion is observed in one ear, the otolaryngologist may prescribe drops in the other ear to enhance the effect.

Owner registration certificate:
BIOCODEX

ATX code for OTIPAX

S02DA30 (Combinations)

Analogues of the drug according to ATC codes:

You should consult your doctor before using OTIPAX. These instructions for use are for informational purposes only. For more complete information please refer to the manufacturer's instructions.

Clinical and pharmacological group

24.015 (Preparation with anti-inflammatory and local anesthetic action for local use in ENT practice)

Release form, composition and packaging

Lidocaine is a local anesthetic. The combination and lidocaine contributes to a more rapid onset of anesthesia, and also increases its intensity and duration.

Pharmacokinetics

Does not penetrate into the body with an intact eardrum.

OTIPAX: DOSAGE

Drops are instilled into the external auditory canal 3-4 drops 2-3 times / day. To avoid contact of cold solution with auricle the bottle should be warmed in the palms before use.

The course of treatment is no more than 10 days.

Overdose

Data on overdose of the drug Otipaks® are not provided.

drug interaction

Currently, there are no data on the interaction of the drug Otipax® with other drugs.

Pregnancy and lactation

It is possible to use the drug Otipax® during pregnancy and lactation according to indications, provided that the eardrum is intact.

OTIPAX: SIDE EFFECTS

Perhaps: allergic reactions, irritation and hyperemia of the ear canal.

Terms and conditions of storage

List B. The drug should be stored out of the reach of children at a temperature not exceeding 30°C. Shelf life - 5 years. Do not use after the expiry date stated on the packaging. After opening the vial, the drug should be used within 6 months.

Indications

For local symptomatic treatment and pain relief in adults and children (including newborns) with:

• otitis media in acute period at the time of inflammation;
• otitis,
• as a complication after the flu;
• barotraumatic otitis.

Contraindications

• perforation of the eardrum;
• hypersensitivity to the components of the drug.

special instructions

Before you start using the drug, you must ensure the integrity of the eardrum. In the case of using the drug with a perforated tympanic membrane, complications may develop due to the contact of the active substance with the components of the middle ear system.

It should be borne in mind that the drug contains active substance, which can give positive test during doping control.

Otipax is a common remedy that is suitable for both children and adults, including pregnant and lactating women. However, before using it, it is important to familiarize yourself with the conditions of storage and use.

Otipax expiration date after opening

Each drug has its own expiration date, after which it is strongly not recommended to use the medication. You can easily find out about the shelf life of any product - just look at the packaging. The date of manufacture must be indicated there. last day use.

Otipax is available in the form of drops. There are several bottle size options.

Bottle in 40 ml closed kept for 5 years. In case of opening, the shelf life of the drug is reduced to six months. A 15 ml bottle is also available. It is stored unopened for three years. Once the drug has been opened, the shelf life is reduced to one month.

The drug can also be used if its expiration date ends in 5-10 days.

During storage, nothing happens to the drug - it does not change color, smell or consistency.

To recognize a medicine with a marriage, you need to carefully examine the packaging for integrity. Then you should pay attention to the design of the same packaging: font, size of letters and numbers, as well as spelling and punctuation errors. After opening, inspect the drug itself - it should be homogeneous and transparent.

Experienced pharmacists argue that if the drug has expired, it can be used. However, there is no guarantee that the drug will work.

IMPORTANT! Children under 12 years of age should not use expired medicine.

How to store?

Any room in the house is suitable for storing medication. The main thing is that its temperature does not exceed 28 degrees Celsius, and this place is inaccessible to children.

Another drug is "afraid" too low temperatures so you can't store it in the freezer.

Analogue drugs:

• Folicap;
• Otirelax;
• Lidocaine + Phenazone.

Storage conditions for medicines in pharmacies and clinics

Otipax does not require special conditions of detention. Therefore, at the points of sale, as well as in medical institutions the product is stored in special boxes or cabinets.

Expired drug disposal process

After Otipax has expired, it is handed over to special companies for disposal. This happens in several ways:

• chemical disinfection;
• steam sterilization;
• burning in special furnaces;
• processing using microwaves.

REFERENCE! During the sale and storage of medicines, the pharmacist is guided by a large list of documents. The main ones are: Federal Law No. 61-FZ "On the circulation of medicines" dated 04/12/2010, Order of the Ministry of Health and Social Development of the Russian Federation dated 08/23/2010 No. 706n (as amended on 12/28/2010) "On approval of the Rules for the storage of medicines".

Scope of Otipaks

The medication is available in the form of drops of 15 or 40 ml. It looks like a rectangular box, the main color of which can be blue or pale pink.

The country of origin of the medicinal product is France.

Otipax is used for barotraumatic edema, otitis media, including acute form accompanied by inflammation. It is also used to combat hearing complications after the flu. The drug has analgesic and anti-inflammatory effects.

You can buy the drug at any pharmacy without a prescription.

Otipax is a medicine with many positive reviews. However, it is best not to self-medicate, but with painful sensations see a doctor.