Relatively recently, Valoserdin began to be added to their number. Interesting is the fact that none of these drugs are listed as "cardiac". According to modern classifications, they are included in the group of sedative medicines. However, due to the special composition, these drops have a good antispasmodic effect, which slightly dilates the coronary vessels. This effect for some time increases blood flow to the heart, which relieves pain. In addition, all drugs are similar and there is not much difference. In which case they can be replaced with each other.

Compound

Nevertheless, a very common question among patients remains: “What exactly is the difference between Corvalol and Valocordin?”. It is worth starting from the chemical composition of both drugs. The common components are:

• Phenobarbital is the main element that has a calming effect on the human nervous system.
• Ethylbromisovalerianthil and its analogue in Corvalol is the ethyl ester of alpha-bromisovaleric acid. Almost identical substances that act as bromine donors in the preparation.
• Ethanol.

The only difference in composition between the two medicines is the presence of mint and hop oil in Valocordin, and caustic soda in Corvalol. They have antispasmodic and sedative effects on the body, but through slightly different chemical pathways. Valoserdin is another analogue of these funds. Now it can be found in the pharmacy even more often than the classic "heart" drops.

Manufacturers

You need to know that Valocordin, Corvalol and Valoserdin are produced by different companies. The first drug is foreign, created by the German company KrewelMeuselbachGmbH. It is interesting that this tool has not been used in Europe for a long time due to its obsolescence. However, the company continues to synthesize the chemical formula for the countries of the former USSR, where it is still very popular, especially among the elderly.

Corvalol and Valoserdin are domestic analogues of Valocordin. In fact, these are generics of the original German formula, adapted for local raw materials. Thanks to this, they provide exactly the same effect, but at a lower price. Then why pay more?

Effects

Indications for the use of Corvalol, Valocordin and Valoserdin are the following situations:

• neuroses, stress,
• irritability and emotional lability,
• intestinal cramps, colic,
• pain in the left chest area
• cardiopalmus,
• rise in blood pressure,
• sleep rhythm disturbances.

After taking soothing drops, relaxation of the smooth muscles of the vessels occurs, which leads to their expansion. Normal blood circulation is restored, and the patient begins to feel better. Often this effect is mistaken for the treatment of various "heart" diseases. It is important to understand that the drugs of the Valocordin group only stop the manifestations and symptoms, but do not cure the disease. Their action is limited by the residence time of chemical components in the blood.

Side effects and contraindications

It must be remembered that Corvalol, Valoserdin or their analogues are used only in the territory of the post-Soviet countries. This is due to the low cost of drugs and their relatively high efficiency. However, the whole world has not used these drops for several decades. The thing is that phenobarbital, which is part of the medication, has a number of undesirable consequences of its effect on the body. Now there are safer analogues that better fight the symptoms of neurosis, but their cost is slightly higher.

Adverse reactions that occur with regular or improper use of Valocordin and its analogues include:

1. Feeling of detachment. Many experience apathy or even depression.
2. Inflammation of the mucous membranes. The most common are rhinitis and conjunctivitis.
3. Dizziness and general weakness.
4. Disorders of the CNS. There may be problems with coordination. The patient cannot fasten a button or get a thread into the eye of a needle.
5. Hemorrhagic diathesis.

With an overdose of medications, a significant drop in blood pressure up to collapse can develop. Therefore, do not abuse these funds.

Contraindications to their use are the following:

• individual intolerance to the components that are included in the chemical composition of drugs,
• pregnancy and lactation period,
• condition after traumatic brain injury,
• hepatic, renal failure,
• chronic alcoholism,
• in children.

conclusions

There is practically no significant difference between Valocordin, Valoserdin or Corvalol. Everyone decides for himself which drops suit him best. The main thing is not to abuse medications, since long-term use of phenobarbital negatively affects the functioning of the whole organism. This group of medicines is symptomatic and cannot be used as a base remedy.

Nevertheless, among the elderly, the popularity of "drops from the heart" does not fade, due to their good efficiency and low cost.

Sometimes it turns out that some kind of nervousness or stress comes over me. Most likely from overstrain or fatigue, because it happens exactly at the time of compiling and submitting reports. During such periods of nervous stress, I take Valoserdin. It so happened historically that the choice fell on him. And if something helps me, then I do not change the drug. Since it is Russian-made, it happens, as a rule, in any pharmacy.

Every day I get nervous a lot, orders from my superiors that can ruin my mood with one phrase, or even bring me to a breakdown. I suffered for a long time, my heart was seized every day, but not so long ago I found out about the medicine Valoserdnin, which my friend advised me. It really helped me, because I tried a bunch of drugs for seizures, it has a pleasant taste and an instant effect.

Everyone in my family has problems with blood pressure, and I am no exception. And you can’t hide from stress and anxiety anywhere, then you have to worry about the children, then something at work. The therapist advised to keep Valoserdin on hand for such cases. Before that, I took another more familiar imported remedy, but this drug helps no worse, it calms quickly, the price is quite affordable and there is always one in the pharmacy.

My parents always relieved stress and anxiety with corvalol, my father's morning as a leader always began with this smell. When I grew up, I didn’t follow suit, but stressful work, constant unrest made me think about how to help myself. I started drinking Corvalol, but I didn’t feel any visible effect, my therapist advised me to replace it with Valoserdin, since it also has a sedative effect and indeed, it relieves my inner excitement better and I take it before bedtime, it helps, and it tastes more pleasant. This is apparently due to mint and hops. Mom, the same was satisfied with them.

These drugs really have a sedative effect, the main thing is in a moderate dosage. I am taking Valoserdin. I used to try to take others, but, in my opinion, Valoserdin is more pleasant. I usually take it before bed, but sometimes in the middle of the day. I noticed that the fewer drops you dilute, the better. You feel calmer like the effect, soft and not sleepy.

In our family, the third generation, if necessary, uses Valoserdin. A wonderful remedy: for neuralgia, and for a good sleep, even with colic, she took it - it helped right away. Everyone in the family has their own sores, and everyone takes Valoserdin. I think that the cost is very low, compared to other drugs. Maybe someone has a different opinion, but I am writing on behalf of the whole family. It helps five people, so it's really effective.

🔻8 most effective analogues of Valocordin

The original drug is produced by the German company "Krevel Moiselbach GMBH" exclusively in drops. It can be replaced with a Russian cheaper analogue Corvalol. An additional advantage of this medication is the release in the form of tablets.

8 most effective analogues of Valocordin

The effectiveness of a drug determines the quality of the raw materials used for its production and technological process. Therefore, with the same composition, some funds will cost more than others. When choosing a substitute, you must be guided by the reputation of the manufacturer. We have compiled a list of the 8 most common ones:

pharmachologic effect

Due to its diverse composition, valocordin has a multifaceted effect on the human body. First of all, it is valuable as a mild hypnotic and sedative. Also in medicine, its properties have been used to dilate blood vessels and relieve spasms.

Composition of Valocordin

Valocordin is a complex medicine, which includes two active ingredients and four auxiliary ones:

1. Main active ingredients:

• Ethyl bromisovalerianate - has a calming effect on the body, and also has a pronounced antispasmodic effect. When it is taken, the receptors of the nasal, oral cavity and pharynx are irritated. The signal coming from them to the brain reduces the excitability of the subcortical structures of the brain and enhances inhibitory processes.
• Phenobarbital is a popular ingredient that was widely used until recently. This substance is part of such drugs common in the CIS as Corvalol and valocordin, as well as foreign luminal. The reason for limiting its circulation today was its inclusion in the list of narcotic, psychotropic drugs. Low doses of phenobarbital calm, large - have a hypnotic and anticonvulsant effect.

1. Auxiliary components:

• Peppermint oil - due to its ability to irritate the receptors of the walls of organs, it can relieve spasms, dilate blood vessels, promote the removal of bile, and also has an antiseptic effect.
• Hop cone oil - has a multifaceted effect. Its active ingredients contribute to the release of bile, urine, help fight inflammation, regulate water-salt metabolism and have a calming effect. In addition to valocordin, hop cones are part of Novopassit.
• Ethyl alcohol 96%.
• Water.

Indications for use Valocordin

As an independent remedy or one of the components of the course of treatment, Valocordin is prescribed for:

• Early stages of arterial hypertension.
• Tachycardia.
• Pain in the region of the heart.
• With sleep disorders associated with trouble falling asleep.
• Nervous states.
• Hypochondria.
• Increased irritability.

This medication is used as a component of complex therapy for diseases that are accompanied by spasms of the muscles of the digestive tract. For example, it is prescribed to patients with biliary or intestinal colic.

Contraindications

This drug can not be prescribed to people with hypersensitivity to any of the components of the drug, as well as to patients with severe disorders of the kidneys and liver.

Due to its ability to depress the nervous system, Valocordin is prescribed with caution to patients who drive a car or engage in any activity that requires a quick reaction and concentration.

How to use Valocordin

Valocordin is sold exclusively in the form of drops that are taken internally before eating. Before taking them, they must be dissolved in a small amount of clean water.

The standard treatment regimen provides for 2 or 3 times the drug. A single dosage for adults is 15-30 drops, for a child - 3-15 drops per day. The duration of the therapeutic course is determined by the doctor.

Drug interactions of Valocordin with other drugs

It is not recommended to simultaneously prescribe valocordin and methotrexate, since in this case the side effects of the latter will be more pronounced. It must also be remembered that valocordin enhances the effect of drugs with similar properties. These include:

• sleeping pills;
• injections for local anesthesia;
• painkillers.

In turn, drugs containing valproic acid derivatives, as well as drugs that depress the nervous system (for example, doxylamine), potentiate the work of valocordin.

Phenobarbital affects the functioning of the liver. Therefore, this substance can reduce the effectiveness of drugs, the cycle of transformations in the body of which affects this organ.

Side effects

The negative effects of treatment with these drops are minor. First of all, it is drowsiness, decreased ability to engage in activities that require increased concentration of attention, dizziness. Individuals may develop allergic reactions. In this case, the course of therapy is recommended to be interrupted.

Phenobarbital and bromine, which is part of ethyl bromisovalerianate, have the ability to accumulate in the body. Therefore, a long course of treatment can lead to addiction and bromine poisoning. This may be evidenced by depression, detachment from reality, inflammation of the mucous membrane of the eye, runny nose, hemorrhagic diathesis, problems with coordination.

The appointment of Valocordin during the period of gestation and lactation

According to the instructions, the drug can be shown to expectant mothers only in certain cases when it is not possible to replace it with an analogue or the health benefits of the mother outweigh the likely risk to the child. For the period of treatment, it is necessary to interrupt breastfeeding.

The price of Valocordin and its analogues

The cost of even the original tool is small. The price range of 20 and 50 ml bottles is and respectively. But its counterparts are even cheaper:

What is the difference between Valocordin and Valocordin-doxylamine (VD)

Many people are misled by the presence of the word "valocordin" in the name of the second medicine. In fact, this is the only complete similarity between the two drugs. The active substance in the composition of the VD is doxylamine succinate, the remaining components perform an auxiliary function.

Like its namesake, VD has a hypnotic and sedative effect, but its mechanism is fundamentally different. It does not irritate, but blocks the histamine-H1 receptors of the ethanolamine group. Due to the difference, this medicine can be prescribed to combat allergies, itching. And when combined with other medicines - for colds, coughs.

Prohibition of Valocordin and its analogues

In our country, this drug is very popular as a cure for heart disease. But upon careful reading of our article, and for advanced users of the instructions, the reader will notice that none of the components of valocordin in any way affects the functioning of the heart. Why is it not the first generation of our fellow citizens who intensively heals their hearts? The fact is, this medication helps to fight the symptoms that accompany many cardiopathologies: anxiety, pain in the heart, tachycardia.

Also, magic drops make it possible for a person to forget a sound sleep and have a good rest. At the same time, general well-being improves, but heart problems remain and imperceptibly gradually progress. Moreover, it becomes more difficult for the doctor to analyze the patient's history, since many of the characteristic signs are masked by taking drops.

Above in the article, we mentioned that one of the main active substances, when taken for a long time, forms addiction, and the second leads to the accumulation of bromine and subsequent poisoning. A person with an ingrained habit of using the drug gradually ceases to receive the expected effect from the recommended doses and begins to exceed them. According to official statistics, every year about 50 people with signs of phenobarbital poisoning are admitted to the emergency department of St. Petersburg alone.

Against the background of all of the above, the fact that the favorite of the domestic consumer and its analogues is prohibited for sale in America, as well as in a number of European countries, does not look shocking. Interestingly, the manufacturer himself, Germany, also falls into this list. Let's say more, for more than a decade, phenobarbital derivatives have been dispensed without a prescription only in the CIS countries.

It is hard and necessary to give up the usual, incredibly cheap, but far from safe drops. Fortunately, modern medicine has something to offer in return.

How to replace valocordin and corvalol

The most popular sedative mixture contains a synthetic drug

For the first time, I had a chance to learn about this demonic component of the harmless and popular Corvalol from the operatives of the ORCh No. 2 of the Criminal Investigation Department of the Ministry of Internal Affairs, a unit fighting drug trafficking. When drug addicts are “taken”, the latter often beg for one thing - to bring two or three vials of Corvalol into the cell! And not from a rapid heartbeat. And to at least partially weaken the breaking. Corvalol contains the synthetic drug phenobarbital or, the second name is luminal. In the concentration camps of Nazi Germany, they tried to create an impeccable “medicine against fear” on its basis. And the work of fascist psychopharmacists has not been declassified to this day.

“... Corvalol is practically unknown outside of Eastern Europe and the former USSR (although its German equivalent, Valocordin, is available in some Western European countries). The main active constituents of Corvalol are considered drugs or controlled substances in a number of countries and are prohibited from import and sale. In particular, Corvalol was banned from being imported into Lithuania and the United States…”

Banned? And they did it right! - perhaps, that involuntarily breaks out from our interlocutor, in response to the above Internet quote. Nadezhda Dmitrievna Volkova – Candidate of Medical Sciences, Professor of the Department of Pharmacology of the Medical Institute of the Lomonosov Moscow State University. N.P. Ogareva, confirms that the slogan “Beware of Corvalol!” has every right to exist. Phenobarbital is a derivative of barbituric acid, explains Nadezhda Nikolaevna. And barbiturates are considered very dangerous drugs. Barbiturates are especially dangerous when they are taken with alcohol, then their combined effect on the central nervous system is especially strong. The composition of Corvalol is, in fact, the same explosive mixture. That is, alcohol and phenobarbital. The action of the narcotic component of this popular medicine is enhanced by bromisovaleric acid. As a strong sleeping pill, barbituric acid derivatives have been widely used since 1903. This is Amytal, Nembutal. Subsequently, such barbiturates as sodium etaminal, sodium barbital, ceased to be used in pharmacology. And not only because more modern drugs have appeared. Barbiturates, being the strongest sleeping pills, however, disrupt the normal course of sleep, accumulate in the body (cocumulate), and for a long time, even after a single use, drowsiness continues. Drug addiction develops very quickly. As a rule, within a month, even if you strictly follow the suggested dosage. But when a Russian person strictly followed something.

Volkova makes quick calculations. It turns out that 30 drops contain 0.01 centime of phenobarbital - then it acts as a sedative. At 0.1 centime of the active substance, a strong hypnotic effect occurs. At high doses - illusory-pleasant sensations, similar to intoxication. But at the same time, there is an anticonvulsant effect. (Here it is, that fine line of dosage, which only a specialist can determine!)

Since the cult drink of many Saransk drunkards - tincture of capsicum - has risen in price by more than one ruble, the eyes were attracted by cheap, 9-11 rubles per 25-gram bottle, smelly Corvalol. And - where are the heroes of the Erofeev saga "Moscow-Petushki", with their harmless perfume cocktails! Empirically (this is a real story of a real alcohol addict) it was established: if you buy the notorious "pepper" and a bottle of Corvalol - total whole - and use it all together, then the desired state is guaranteed for 12 hours. This is not a state of alcoholic euphoria, but some kind of pathological calm bordering on idiocy. My interlocutor, a drug dispensary patient, nicknamed Korvalolych by his colleagues, admits that he was so addicted to this “drink” that he preferred it to “pepper” even if he had at least some money. He knew that after taking two or three bottles, he would not experience that irrepressible, uncontrollable desire to "catch up" as when consuming a glass of so-called draft wine or diluted technical alcohol. Idiotic apathy will certainly be replaced by a dead dream. (Remember, in the "Striped Flight" the king of beasts passed out because "the luminal ate itself"?) Korvalolitch noticed that in the morning the same saving idiotic apathy, but not purely alcoholic terrible hangover anxiety, continued. And even the minimum amount of alcohol knocks down. Direct Savings! Once, when Korvalolych received a sum of a thousand rubles, he, as usual, took a “cordial” in a pharmacy. Used three bottles in two hours. He doesn't remember anything after that. Vaguely - the police department and the morning clarification of consciousness in the drug dispensary. The experience of the unfortunate person is confirmed by the pharmacist Volkova: “Barbiturates are excreted from the body very slowly, practically do not break down and retain their chemical formula, so the coma that can occur with an overdose is very severe and does not lend itself to traditional medical procedures.” Narcologist, head of department No. 1 of the drug dispensary Yuri Anatoly Yurasov during his practice recalls about two dozen such “corvalols”: “Literally, every such transcendental intake of corvalol can be compared with a concussion in terms of its consequences for the mental abilities of a person and the state of his emotional sphere. However, phenobarbital with alcohol in narcology ... is used. This is the famous "Popov's mixture", which is a 30% solution of medical alcohol and phenobarbital tablets. "Popov's mixture" prevents alcoholic epilepsy and psychosis. And at the first stage of detoxification (cleansing the body), it is given to most patients of the dispensary. This alone indicates how strongly this active substance affects the central nervous system! It is indeed a psychotropic drug.

Moreover, in the 90s, when the drug dispensary did not have any funds to purchase special drugs, in order to prevent psychosis and epileptic convulsions in patients, they used ... the same Corvalol. True, former employees and former patients talk about this, not without fear. Of course, it could fly in, but the doctors really saved the lives and psyches of the unfortunate!

If, in search of the cheapest possible drink, an alcoholic pays attention to Corvalol, this will be tantamount to a death sentence for him. This year, two people, a man and a woman, ended up in the “acute” department No. 2 of the drug dispensary with phenobarbital poisoning. But there are probably more. These simply admitted that they consumed. And such a trend "at the bottom" is already outlined. But not only "at the bottom" ...

And my heart wants peace

The rapid dependence on luminal threatens the older generation, because for so many older people, cheap affordable Corvalol is a salvation from all sores. As well as for people with low incomes. There is no data for Mordovia, but on the scale of Russia, the figure is amazing. For a year, Russians consume up to 70 million (!) Vials of Corvalol and 9 million - Valocordin. It turns out that Corvalol in Russia is the most common, affordable and cheap tranquilizer and antidepressant. Naturally, bringing a stable and considerable profit for both manufacturers and traders. As a mind-altering chemical, tranquilizers are no different from so-called soft drugs.

The owner of the network of pharmacies, Alexander Nikolaevich Glushkov, testifies: “Corvalol is in constant stable demand. True, I have not noticed drunks yet. I just missed them! I also refused the tincture of pepper. There are no super incomes, but there are a lot of troubles with this brotherhood. And it beats prestige…” But God bless them (or the devil?) with alcoholics. But grandmothers and just poor people who take "heart" drops? Pharmacy consultant Julia testifies that, indeed, many, who look like village grandmothers, buy these “droplets” in dozens of bottles.

Any competent doctor knows that Corvalol, as well as its more expensive analogues Valocordin and Valoserdin, have a very indirect relationship to the medicine "from the heart". In fact, they don't have any at all. The head of the cardiology department of the Republican Clinical Hospital, Elena Aleksandrovna Tyulenina, just says: “We don’t work with Corvalol.” In general, after a series of conversations with doctors and pharmacists, I got the impression that Corvalol does not cure anything, but, like any drug, it calms, lulls and relieves pain. Reduces feelings of anxiety, fear, anxiety. But if you take it for years to calm down, then the effect gradually decreases and you have to drip more and more into a glass. And our grandmothers' relatives secretly begin to consume up to one, or even more than 25 ml bottles per day! On the sly. Without admitting to real doses of consumption. They also have no idea what the “cure for fear” is made of.

I knew a middle-aged warehouse manager, not an alcoholic, not a hysteric, who loved strong tea and daily "from the heart" took a vial of Corvalol. "So what? It's the same medicine. » With prolonged use, this medicine not only impairs the functioning of the liver, kidneys and other important organs, but also weakens memory and even leads to depression. But if a person is used to taking a ml of the drug per day, then with a sharp cancellation it will be even worse. There are persistent insomnia, anxiety, hallucinations, reminiscent of "delirious tremens". In addition to luminal, the body also accumulates bromisovalerianate and leads to chronic bromine poisoning. And it causes respiratory diseases, allergies, sexual disorders, chronic pain and much more. A large dose can lead to a deep loss of consciousness and death, since barbiturates have a depressing effect on the respiratory center. And who now opens and meticulously determines, God forgive me, the cause of death among rural pensioners?

“You will write there, and you will only make advertising for drug addicts!” - complained a familiar narcologist. It can be answered that at one time the proposal to ban the over-the-counter free sale of barbituric drugs in Russia was made by none other than representatives of the Federal Drug Control Service. What caused the assault on pharmacies by pensioners in big cities - this magical drug was bought up in boxes! Then the proposal of the drug police did not pass. He was somehow quietly "lowered on the brakes." And the drug addicts themselves consider phenobarbital, as they say, "bespontovy". Yes, they admit that he "holds", but there is no "arrival". Translated into a common language - intoxicating, but does not bring vivid sensations. In general, all experts, except for Volkova, were reluctant to speak on this topic, asking to see the material before going to press. Two doctors categorically refused to refer to them. Oh my God! Why would it? They would simply say that any medicinal substance is good as long as it brings the pathology back to normal. So - under the control of the doctor. The American star fell asleep and choked in the bathroom under the influence of a hundred times more expensive psychotropic drugs, but in essence they are not much different from the contents in every sense of a cloudy bottle with its specific aroma of unpredictability.

What can replace Corvalol

Professor of the Department of Clinical Pharmacology Nadezhda Volkova gives the following recommendations. Corvalol can be used, but strictly following the instructions - no more than drops three times a day before meals. But not constantly from month to month, especially from year to year, but in emergency cases. For older people, she generally does not recommend using this drug during the day, but only at bedtime. It is even better and safer in all respects to use herbal sedatives. Novo-Passit is especially effective as a soothing tincture that combines several types of plants. But this is a relatively expensive "cocktail".

Much cheaper tablets and tinctures of motherwort, valerian, passionflower. You can buy these plants in dried form in the phytodepartments of pharmacies and prepare infusions at home, according to the attached instructions and recommendations. In general, pharmacies now offer a large number of herbal teas, fees that have a calming effect.

Which is better to take: drops of Corvalol or Valocordin? How effective are these drugs in treating the heart?

Approximately half of patients suffering from painful sensations in the heart are not real "hearts". At the same time, there is a direct connection between constant nervous shocks, disorders and heart diseases. People often experience, endure serious stress, fatigue, huge emotional stress. And many patients even perceive everything too closely, worrying about the little things.

All this leads to heart pain, constant feelings of fear, anxiety, insomnia, panic attacks. To forget about this condition and solve the problem with nerves, many resort to sedatives or sedatives. Valocordin and Corvalol drops are considered the most popular cardiac drugs. Let's try to figure out what the difference is, and which of the remedies is better to choose for treatment.

Description of drugs

Both Corvalol and Valocordin are considered relatively affordable sedative medications. They have the same mechanism of action on the body. These drugs are affordable and always available in pharmacies.

Valocordin is a combined German sedative that contains phenobarbital, mint and hop esters, alcohol and water.

The substance phenobarbital has a vasodilating and sedative effect. It acts on the body as a sleeping pill. In this case, the drug slightly lowers the pressure. The content of ethyl alcohol also provides a slight sedative effect, helps to fall asleep faster, and relieves pain. Essential vegetable oils dilate blood vessels and give an analgesic effect.

Valocordin, produced by a foreign pharmaceutical company, is supplied to different countries of myrtle.

Corvalol is a Russian substitute for Valocordin. It contains ethyl ether, phenobarbital, alcohol vapours, peppermint oil and pure water.

If the patient drinks these drugs for a long time in a high dosage, then this is fraught with the appearance of bromism (bromine intoxication), which causes prolonged depression, apathy, inhibition of the reaction, and sometimes even the formation of a tumor in the brain. At the same time, Corvalol, however, like Valocordin, can cause drug dependence. This condition is dangerous and difficult to cure later on.

Therefore, with long-term treatment with Corvalol, it is worth considering how to replace it. To do this, it is better to choose another, less aggressive medicine, for example, motherwort, validol or hawthorn.

Valocordin or Corvalol: which is better?

Almost all doctors claim that these drugs are identical, and each is suitable to replace the other. The only difference is the presence of hop cones ether in Valocordin, which has a calming and analgesic effect.

Now another analogue of Corvalol is popular - Valoserdin, with a similar composition. All of these drugs are sold without a prescription.

At the same time, the cost of a Russian drug is much lower than that of a foreign substitute. Therefore, Corvalol has won demand among elderly patients.

Usually, after the use of Valocordin or a domestic preparation, the pain in the cardiac region subsides. However, these drugs are not able to cure blood clots in the vessels or ischemia. They only postpone treatment for a while, reducing the patient's chances of preventing an attack of angina pectoris and the development of a heart attack.

Features of taking Valocordin

Valocordin is a combination drug whose therapeutic effect is based on the pharmacological properties of its ingredients. Phenobarbital, present in the drug, has a mild hypnotic and sedative effect. The substance helps to reduce the excitability of the nervous system, accelerates falling asleep. The tool relieves chest pain on the left side.

Valocordin is indicated for:

When not to take the drug:

• In case of intolerance to any components of the drug;
• With severe dysfunctions of the liver and kidneys;
• When carrying a baby and lactation;
• In childhood.

It is worth being careful when treating with Valocordin for patients with hepatic pathologies, in a state of hangover, with dependence on alcohol, brain diseases, since alcohol is present in the medicine.

Description of Corvalol

Corvalol is a clear solution with a specific taste and aroma of herbs. The effect of the drug is determined by the components that make up its composition. Corvalol is also available in the form of tablets.

It is prescribed as a sedative and mild antihypertensive agent for:

• Disorders of the nervous and cardiac systems;
• Bad dream;
• Rapid pulse;
• Neurosis and stressful conditions;
• tachycardia;
• excessive irritability;
• Excited states with vegetative signs;
• Spasms in the digestive organs.

The drug is prohibited to take in case of:

• Hypersensitivity to the ingredients;
• Hypotension of a chronic type, because in this case the pressure needs to be raised, and the drug reduces it;
• Serious kidney and liver disease.

In general, the drug is well tolerated. However, some patients experience drowsiness, dizziness, and lethargy as a side effect.

If Corvalol is taken for a long time, dangerous bromine poisoning occurs, which manifests itself in the form of depression, rhinitis, conjunctivitis, apathy, lethargy.

Scientific research

Hop ether and phenobarbital in heart drops have a subtle hypnotic effect, and mint ether calms the nerves. No more problems associated with the central nervous system and heart, these drugs do not solve. This is described in the instructions for Valocordin, where among the indications there is neither angina pectoris, nor hypertension, nor other heart pathologies.

If you use these medicines without properly treating heart ailments, you will only harm your health. Such self-treatment is dangerous, and the diseases themselves will not disappear.

Corvalol, taken in large quantities, can lead to poisoning and even death.

Now scientists are also exploring the narcotic effect of phenobarbital, because drugs with its content can lead to addiction. Unlike the main component, vegetable esters are harmless to patients who are not allergic to them.

conclusions

Both drugs effectively inhibit the activity of the central nervous system, depressing effect on it, help to overcome anxiety and anxiety, improve falling asleep. Due to the content of plant esters, anesthesia and expansion of the vascular walls are provided. Water in medicines plays the role of a solvent, and a small amount of alcohol serves as a preservative.

Having found out how Corvalol and Valocordin differ, one can judge what helps better from the heart. Both drugs have the same active ingredient. They perform their hypnotic, sedative, hypotonic function with equal efficiency. You can choose an affordable - domestic remedy, without worrying that it "works" worse than a foreign drug.

When drug addicts are “taken”, the latter often beg for one thing - to bring two or three vials of Corvalol into the cell! And not from a rapid heartbeat. And to at least partially weaken the breaking. Corvalol contains the synthetic drug phenobarbital or, the second name is luminal. In the concentration camps of Nazi Germany, they tried to create an impeccable “medicine against fear” on its basis. And the work of fascist psychopharmacists has not been declassified to this day.

“... Corvalol is practically unknown outside of Eastern Europe and the former USSR (although its German equivalent, Valocordin, is available in some Western European countries). The main active constituents of Corvalol are considered drugs or controlled substances in a number of countries and are prohibited from import and sale. In particular, Corvalol was banned from being imported into Lithuania and the United States…”

Banned? And they did it right! - perhaps, that involuntarily breaks out from our interlocutor, in response to the above Internet quote. Nadezhda Dmitrievna Volkova – Candidate of Medical Sciences, Professor of the Department of Pharmacology of the Medical Institute of the Lomonosov Moscow State University. N.P. Ogareva, confirms that the slogan “Beware of Corvalol!” has every right to exist. Phenobarbital is a derivative of barbituric acid, explains Nadezhda Nikolaevna. And barbiturates are considered very dangerous drugs. Barbiturates are especially dangerous when they are taken with alcohol, then their combined effect on the central nervous system is especially strong. The composition of Corvalol is, in fact, the same explosive mixture. That is, alcohol and phenobarbital. The action of the narcotic component of this popular medicine is enhanced by bromisovaleric acid. As a strong sleeping pill, barbituric acid derivatives have been widely used since 1903. This is Amytal, Nembutal. Subsequently, such barbiturates as sodium etaminal, sodium barbital, ceased to be used in pharmacology. And not only because more modern drugs have appeared. Barbiturates, being the strongest sleeping pills, however, disrupt the normal course of sleep, accumulate in the body (cocumulate), and for a long time, even after a single use, drowsiness continues. Drug addiction develops very quickly. As a rule, within a month, even if you strictly follow the suggested dosage. But when a Russian person strictly followed something.

Volkova makes quick calculations. It turns out that 30 drops contain 0.01 centime of phenobarbital - then it acts as a sedative. At 0.1 centime of the active substance, a strong hypnotic effect occurs. At high doses - illusory-pleasant sensations, similar to intoxication. But at the same time, there is an anticonvulsant effect. (Here it is, that fine line of dosage, which only a specialist can determine!)

Since the cult drink of many Saransk drunkards - tincture of capsicum - has risen in price by more than one ruble, the eyes were attracted by cheap, 9-11 rubles per 25-gram bottle, smelly Corvalol. And - where are the heroes of the Erofeev saga "Moscow-Petushki", with their harmless perfume cocktails! Empirically (this is a real story of a real alcohol addict) it was established: if you buy the notorious "pepper" and a bottle of Corvalol - total whole - and use it all together, then the desired state is guaranteed for 12 hours. This is not a state of alcoholic euphoria, but some kind of pathological calm bordering on idiocy. My interlocutor, a drug dispensary patient, nicknamed Korvalolych by his colleagues, admits that he was so addicted to this “drink” that he preferred it to “pepper” even if he had at least some money. He knew that after taking two or three bottles, he would not experience that irrepressible, uncontrollable desire to "catch up" as when consuming a glass of so-called draft wine or diluted technical alcohol. Idiotic apathy will certainly be replaced by a dead dream. (Remember, in the "Striped Flight" the king of beasts passed out because "the luminal ate itself"?) Korvalolitch noticed that in the morning the same saving idiotic apathy, but not purely alcoholic terrible hangover anxiety, continued. And even the minimum amount of alcohol knocks down. Direct Savings! Once, when Korvalolych received a sum of a thousand rubles, he, as usual, took a “cordial” in a pharmacy. Used three bottles in two hours. He doesn't remember anything after that. Vaguely - the police department and the morning clarification of consciousness in the drug dispensary. The experience of the unfortunate person is confirmed by the pharmacist Volkova: “Barbiturates are excreted from the body very slowly, practically do not break down and retain their chemical formula, so the coma that can occur with an overdose is very severe and does not lend itself to traditional medical procedures.” Narcologist, head of department No. 1 of the drug dispensary Yuri Anatoly Yurasov during his practice recalls about two dozen such “corvalols”: “Literally, every such transcendental intake of corvalol can be compared with a concussion in terms of its consequences for the mental abilities of a person and the state of his emotional sphere. However, phenobarbital with alcohol in narcology ... is used. This is the famous "Popov's mixture", which is a 30% solution of medical alcohol and phenobarbital tablets. "Popov's mixture" prevents alcoholic epilepsy and psychosis. And at the first stage of detoxification (cleansing the body), it is given to most patients of the dispensary. This alone indicates how strongly this active substance affects the central nervous system! It is indeed a psychotropic drug.

Moreover, in the 90s, when the drug dispensary did not have any funds to purchase special drugs, in order to prevent psychosis and epileptic convulsions in patients, they used ... the same Corvalol. True, former employees and former patients talk about this, not without fear. Of course, it could fly in, but the doctors really saved the lives and psyches of the unfortunate!

If, in search of the cheapest possible drink, an alcoholic pays attention to Corvalol, this will be tantamount to a death sentence for him. This year, two people, a man and a woman, ended up in the “acute” department No. 2 of the drug dispensary with phenobarbital poisoning. But there are probably more. These simply admitted that they consumed. And such a trend "at the bottom" is already outlined. But not only "at the bottom" ...

And my heart wants peace

The rapid dependence on luminal threatens the older generation, because for so many older people, cheap affordable Corvalol is a salvation from all sores. As well as for people with low incomes. There is no data for Mordovia, but on the scale of Russia, the figure is amazing. For a year, Russians consume up to 70 million (!) Vials of Corvalol and 9 million - Valocordin. It turns out that Corvalol in Russia is the most common, affordable and cheap tranquilizer and antidepressant. Naturally, bringing a stable and considerable profit for both manufacturers and traders. As a mind-altering chemical, tranquilizers are no different from so-called soft drugs.

The owner of the network of pharmacies, Alexander Nikolaevich Glushkov, testifies: “Corvalol is in constant stable demand. True, I have not noticed drunks yet. I just missed them! I also refused the tincture of pepper. There are no super incomes, but there are a lot of troubles with this brotherhood. And it beats prestige…” But God bless them (or the devil?) with alcoholics. But grandmothers and just poor people who take "heart" drops? Pharmacy consultant Julia testifies that, indeed, many, who look like village grandmothers, buy these “droplets” in dozens of bottles.

Any competent doctor knows that Corvalol, as well as its more expensive analogues Valocordin and Valoserdin, have a very indirect relationship to the medicine "from the heart". In fact, they don't have any at all. The head of the cardiology department of the Republican Clinical Hospital, Elena Aleksandrovna Tyulenina, just says: “We don’t work with Corvalol.” In general, after a series of conversations with doctors and pharmacists, I got the impression that Corvalol does not cure anything, but, like any drug, it calms, lulls and relieves pain. Reduces feelings of anxiety, fear, anxiety. But if you take it for years to calm down, then the effect gradually decreases and you have to drip more and more into a glass. And our grandmothers' relatives secretly begin to consume up to one, or even more than 25 ml bottles per day! On the sly. Without admitting to real doses of consumption. They also have no idea what the “cure for fear” is made of.

I knew a middle-aged warehouse manager, not an alcoholic, not a hysteric, who loved strong tea and daily "from the heart" took a vial of Corvalol. "So what? It's the same medicine. » With prolonged use, this medicine not only impairs the functioning of the liver, kidneys and other important organs, but also weakens memory and even leads to depression. But if a person is used to taking a ml of the drug per day, then with a sharp cancellation it will be even worse. There are persistent insomnia, anxiety, hallucinations, reminiscent of "delirious tremens". In addition to luminal, the body also accumulates bromisovalerianate and leads to chronic bromine poisoning. And it causes respiratory diseases, allergies, sexual disorders, chronic pain and much more. A large dose can lead to a deep loss of consciousness and death, since barbiturates have a depressing effect on the respiratory center. And who now opens and meticulously determines, God forgive me, the cause of death among rural pensioners?

“You will write there, and you will only make advertising for drug addicts!” - complained a familiar narcologist. It can be answered that at one time the proposal to ban the over-the-counter free sale of barbituric drugs in Russia was made by none other than representatives of the Federal Drug Control Service. What caused the assault on pharmacies by pensioners in big cities - this magical drug was bought up in boxes! Then the proposal of the drug police did not pass. He was somehow quietly "lowered on the brakes." And the drug addicts themselves consider phenobarbital, as they say, "bespontovy". Yes, they admit that he "holds", but there is no "arrival". Translated into a common language - intoxicating, but does not bring vivid sensations. In general, all experts, except for Volkova, were reluctant to speak on this topic, asking to see the material before going to press. Two doctors categorically refused to refer to them. Oh my God! Why would it? They would simply say that any medicinal substance is good as long as it brings the pathology back to normal. So - under the control of the doctor. The American star fell asleep and choked in the bathroom under the influence of a hundred times more expensive psychotropic drugs, but in essence they are not much different from the contents in every sense of a cloudy bottle with its specific aroma of unpredictability.

What can replace Corvalol

Professor of the Department of Clinical Pharmacology Nadezhda Volkova gives the following recommendations. Corvalol can be used, but strictly following the instructions - no more than drops three times a day before meals. But not constantly from month to month, especially from year to year, but in emergency cases. For older people, she generally does not recommend using this drug during the day, but only at bedtime. It is even better and safer in all respects to use herbal sedatives. Novo-Passit is especially effective as a soothing tincture that combines several types of plants. But this is a relatively expensive "cocktail".

Much cheaper tablets and tinctures of motherwort, valerian, passionflower. You can buy these plants in dried form in the phytodepartments of pharmacies and prepare infusions at home, according to the attached instructions and recommendations. In general, pharmacies now offer a large number of herbal teas, fees that have a calming effect.

🔻🔻List of the most effective analogues of Corvalol

Corvalol is a sedative, antispasmodic, herbal remedy that normalizes sleep and blood pressure (contains valerian extract, mint oil and hop cones) with the addition of phenobarbital in a solution of ethyl alcohol. The action of the drug is due to the combined activity of all components.

Corvalol is an over-the-counter remedy, however, its prescription must be made by a doctor, as there are certain contraindications to its use, as well as a number of side effects. In case of intolerance to the drug, the attending physician selects a substitute for Corvalol, based on the diagnosis and taking into account concomitant conditions.

The main analogues of Corvalol

Corvalol is a generic drug that has an absolutely similar composition as its original - Valocordin (Germany), but it is produced in the Russian Federation and costs an order of magnitude cheaper than its foreign substitute.

Due to the barbiturate present in it, Valocordin helps to reduce excessive motor activity, calms the nervous system, has a hypnotic effect, reduces pain of moderate intensity, lowers blood pressure. Valerian complements the sedative effect, and is also an antispasmodic. Peppermint oil improves blood supply to the myocardium, relieves pain, improves the patient's emotional mood.

The drugs of this group are shown for:

• tachycardia;
• sleep disorders;
• neurotic disorders;
• VSD of hypertonic type.

• with insufficiency of kidney or liver function;
• hypersensitivity to the components of the drug;
• with diseases and injuries of the central nervous system;
• during pregnancy.

Of the side effects, allergic reactions are possible, bromism with long-term treatment with high doses.

Medicines with a similar principle of action:

• Barboval in drops (Farmak);
• Valoserdin in solution (MFF);
• Valemidin liquid (Pharmamed);
• Bellataminal tablets (Vilar), etc.

All these drugs differ in composition, but in general they consist of substances of plant origin and the indications for their use are the same as for Corvalol and Valocordin.

The contraindications are the same, in addition, they are not prescribed for children under the age of 18 and with severe hypotension.

herbal remedies

Herbs and plant preparations can also serve as a replacement for Corvalol. Unlike drugs produced by pharmaceutical factories, infusions and teas do not have such a large concentration of active substances and can be taken in short courses, but for a longer time. Their action does not develop so quickly, and the effect is much softer.

Valerian

The sedative effect of valerian has been known for a long time, and to this day it is the most popular herbal sedative. In the mind of modern man, the words "valerian" and "sedative" are synonymous. The advantages of using it are that even long-term use of it is not addictive, does not have a detrimental effect on the central nervous system. It can be used both as a monotherapy and in combination with other herbs for a faster and more pronounced effect.

Valerian is used both in the form of vegetable raw materials (ground pieces of rhizomes), and in the form of tincture and extract in the form of tablets of 20 mg.

Chamomile (complements a sedative effect, relaxes muscles), Ivan tea (relieves headaches and helps with insomnia), St. John's wort (relieves increased anxiety, relieves pain and fights inflammatory processes in the body), thyme (calms, improves immunity).

Examples of sedative fees:

• Soothing collection No. 1 (wormwood, adonis, valerian, mint, Ivan tea).
• Soothing collection No. 2 (yarrow, fireweed, chamomile, motherwort, St. John's wort).
• Soothing collection No. 3 (oregano, lemon balm, valerian, thyme, milkwort).
• Soothing collection No. 4 (hops, oregano, valerian, chamomile, St. John's wort).
• Soothing collection No. 5 (oregano, chamomile, mint, yarrow, motherwort).

Indications for the use of analogues of Corvalol of plant origin:

• in diseases of the heart and blood vessels with a tendency to arterial hypertension, coronary heart disease;
• with nervousness, anxiety, overwork, stress;
• in violation of falling asleep;
• during premenopause and menopause in women.

All medicines mentioned in this article are sold in pharmacies without a prescription. Exact therapy can only be selected by the attending physician, who understands the causal relationships of the symptoms and conditions that arise. This is also important in order not to miss a more serious diagnosis.

Cognitive-Saving Therapy: Valemidin Instead of Corvalol

Cognitive-saving therapy: valemidin instead of corvalol.

Worldwide, phenobarbital has not been used as a sedative for over thirty years due to its neurotoxicity and addictive potential. However, in Russia in medical (especially in gerontological) practice, there are often unrecorded patients for whom a bottle of Corvalol lasts only a few days. Many of these gullible patients do not assume that such a common well-known drug (or its analogues) can cause significant harm to the health of its barbituric component. Therefore, the format “most importantly, do not die of ignorance” is very relevant today. Patient education requires a preventive approach from the physician; greater than before knowledge about the long-term effects of drugs; persuasive teaching ability. The doctor will not be given any additional time or remuneration for this. Therefore, for many, it is easier to treat a specific acute situation, not paying attention to such “little things” as nerves. However, with Corvalol, everything is much more serious. Barbiturate abuse is both a physical addiction and a mental one; it is more difficult to treat than heroin.

In the mid-twentieth century, in laboratories one could see large jars of luminal, veronal, which biochemists used to create buffer solutions. But after a spate of barbiturate suicides in the 1970s, the regimen for storage got tougher. It must be said that, both at the turn of the century and now, barbiturates were one of the most frequent sources of acute poisoning, which brought the patient to the intensive care unit of toxicological centers. A. E. Luzhnikov (2000) notes that patients with acute poisoning with psychotropic poisons are 65-75% of all patients in toxicological centers, and patients with barbiturate intoxication among them are at least 25%.

Today, the frequency of sources of various intoxications with neurotropic agents in patients of the toxicological center has changed. Compared to the nineties of the twentieth century, industrial poisoning, chemical reagents, accidents, safety violations are less common (Reshetov M.V. 2009). Household poisonings associated with everyday life have become more frequent, for example, in everyday life with improper use or storage of medicines, household chemicals, and also (especially!) When they are used in combination with alcohol intake (Vishnevskaya O. A., 2000 ; Ivanova A.E., Wilcock G.K., 2006), which increases mortality (Luzhnnikov E A. et al., 2000; Livanov G.A., 2003, Wills A.J., Sawle G.V., Guilbert P.R., Curtis A.R.J. 2002). Barbiturate poisoning contributes to mortality because their absorption begins already in the stomach, nervous excitability decreases, the affinity of hemoglobin to oxygen increases, hypoxia and metabolic acidosis develop (Finsterer J. 2004), blood circulation and respiration slow down, up to paralysis of the respiratory center.

The poisonings of the nineties of the twentieth century were characterized by a high frequency of use of barbiturates, organophosphorus compounds, azaleptin, alcohol and its surrogates. In a much more varied and numerous list of modern toxic substances in patients of the toxicological center, mixtures of toxicants often appear: benzodiazepines, opiates, alcohol, barbiturates. At the same time, patients suffering from depression chose barbiturates as a toxicant in 22.3%, alcoholics in 29.5%, and a mixture of psychotropic drugs in 21.5%. With adaptation disorders, 23% of patients chose barbiturates as a poisonous substance, patients with an organic brain disease - in 19% of cases (Reshetov M.V. 2009). However, 16% of patients at the toxicological center used neurotropic poison accidentally, mistakenly (for example, while intoxicated), another 18% - for self-treatment, without calculating the dose or with other intentions, but without the desire to die. As for real suicides, let us remember: the shorter the pre-suicide (and it can last several minutes), the more random will be the choice of means for the implementation of a suicide attempt (Zinoviev S.V., 2002).

What is the most accessible? According to the rating in the market of psychotropic drugs and psychoanaleptics, Corvalol is the leader in terms of the number of packages sold, followed by its analogues valocordin, valoserdine. (Uvarova Yu., 2010). These drugs are dangerous combination of phenobarbital and alcohol. Such a complex sometimes becomes fatal even in spite of small doses. And it is Corvalol that the irresponsible population prefers for amateur "stopping" of alcohol withdrawal (Reshetov M.V. 2009). On the other hand, quite literate patients, having started taking Corvalol for sedative purposes, are sometimes not very aware of its danger. As a result, both can get poisoning with barbiturates.

If we talk about chronic troubles determined by long-term use of barbiturates, then as long as the body's defense systems are able to neutralize the toxicant, clinical symptoms may not occur. With decompensation of protective and regulatory systems - excretory, detoxification (microsomal oxidation, conjugation), mono-nuclear-macrophage, the accumulation of toxins in the body begins (Livanov G. A., Kalmanson M. L., Tikhomirov S. M., 2000). Decompensation of protective systems leads to the accumulation of toxic products in high concentrations. This is no longer latent transient endotoxicosis of the zero stage (Chalenko V.V., Kutushev F.Kh., 1990), but the stage of decompensation. With increasing doses of barbiturates, the possibility of substance abuse increases (Nimeus A., Traskman-Bendz L., Alsen M., 1997).

Diagnosis of poisoning is often difficult due to difficulties in contact with the patient, it is not always possible to rely on anamnesis data (G. A. Livanov, M. L. Kalmanson, S. M. Tikhomirov, 2003). With frequent and unsystematic intake of barbiturates, concentration of attention and memory decrease: for example, forgetting that Corvalol has already been taken, the patient uses it repeatedly, but phenobarbital is a long-acting barbiturate, and the effect of summing its doses contributes to the rapid progression of encephalopathy. "Stupidity", as well as unsteadiness of gait, slowing of the pace of thinking and speech are most noticeable in elderly and old patients. They should especially be warned against the harmful effects of frequent use of Corvalol and its analogues, because one package contains a daily dose of phenobarbital for a barbituric addict. (Reshetova T.V. 2013). You can not take Corvalol and "for insomnia", because. Phenobarbital destroys the structure of sleep, and a decrease in its dose dramatically lengthens the phases of REM sleep: nocturnal hyperhidrosis, nightmares, and persistent insomnia appear for several weeks.

The abrupt cancellation of phenobarbital leads to an evil-dreary dysphoric mood, anxiety, restlessness, periodic fever, tremor of the head, hands, feet; twitching of the muscles and eyelids when closing the eyes, nausea and abdominal cramps, and in the apogee - convulsions and epileptic seizures.

Therefore, barbiturates should not be canceled immediately, one should gradually replace part of corvalol (= valocordin, valoserdine) with valemidin over several weeks until a complete replacement. Valemidin is similar in action, but does not cause addiction or other negative effects on the central nervous system. The effect of a significant improvement in cognitive functions (attention concentration), memory retention with a significant decrease in anxiety has been proven for valemidin (Reshetova T.V. Zhigalova T.N. Gazieva A.A. 2013). Valemidin includes tinctures of valerian, motherwort, hawthorn, peppermint, and for their synergy - one tablet of diphenhydramine (50 mg) for the entire bottle (50 ml).

The slower the transition will be made (replacing 1-3 drops per day with corvalol for valemidin), the more favorable the prognosis. For example, after a regular evening intake of 30 drops of Corvalol “for insomnia”, on the first day of the program, you should take 29 drops of it and 1-2 drops of valemidin, then 28:2 drops, 27:3 drops, etc.).

If valemidin is prescribed for the first time, its single dose is 40 drops (if blood pressure is elevated) or 20 drops if the pressure is normal. In addition to reducing anxiety, valemidin has a vegetative-normalizing effect, which is also very useful for autonomic dysfunction - an essential component of withdrawal symptoms. With a vegetative crisis in mild cases, "ambulance" is drops of valemidin; with somatoform autonomic dysfunction - it is more expedient to take a daily course for 2-3 weeks. Valemidin is taken for anxiety, anxious insomnia, autonomic dysfunction of various origins (stress, menopause, premenstrual syndrome, etc.) both on demand and in a course of 2-3 times a day for 2 weeks. Valemidin should not be used for hypotension, bradycardia< 55 в минуту; беременности, лактации. У детей до 18 лет эффективность и безопасность не исследовались. Но самая важная ниша применения валемидина – это зависимость от корвалола и его аналогов. При небольших дозах, редких приемах корвалола (не чаще 1 раза в день), плавный медленный переход на валемидин может быть успешно осуществлен в условиях амбулаторного лечения. При длительном приеме корвалола и его аналогов, в дозах выше 30 капель несколько раз в день, необходима терапия прикрытия, чаще всего это можно сделать на 2-3 месяце курсового лечения специальными психотропными препаратами, не вызывающими зависимости, когда депрессия, тревога и бессонница – контролируются, а в состоянии уже достигнута ремиссия. Отменять барбитураты надо постепенно, при тщательном наблюдении за пациентом, а в тяжелых случаях – в стационаре с терапией прикрытия, в которую желательно включить триттико из-за его антикрейвингового эффекта (Решетова Т.В. 2012), но нельзя включать фенотиазины, так как они могут спровоцировать судорожный синдром.

Hospitalization for barbiturate poisoning has now become slightly longer due to the fact that those patients who used to die are now receiving non-addictive psychotropic drugs; metabolic antioxidants, antihypoxants and, as a result, have more favorable treatment outcomes. In conclusion, I would like to note the recent positive trend in many of our contemporaries to take care of their own health, both physical and mental.

In medicine, as in jurisprudence, “ignorance of the laws does not exempt from responsibility”, in the case of Corvalol, for one’s health.

The information is intended for healthcare professionals. There are contraindications. It is necessary to read the instructions of the mentioned drugs.

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🔻8 most effective analogues of Valocordin

The original drug is produced by the German company "Krevel Moiselbach GMBH" exclusively in drops. It can be replaced with a Russian cheaper analogue Corvalol. An additional advantage of this medication is the release in the form of tablets.

8 most effective analogues of Valocordin

The effectiveness of a drug determines the quality of the raw materials used for its production and technological process. Therefore, with the same composition, some funds will cost more than others. When choosing a substitute, you must be guided by the reputation of the manufacturer. We have compiled a list of the 8 most common ones:

pharmachologic effect

Due to its diverse composition, valocordin has a multifaceted effect on the human body. First of all, it is valuable as a mild hypnotic and sedative. Also in medicine, its properties have been used to dilate blood vessels and relieve spasms.

Composition of Valocordin

Valocordin is a complex medicine, which includes two active ingredients and four auxiliary ones:

1. Main active ingredients:

• Ethyl bromisovalerianate - has a calming effect on the body, and also has a pronounced antispasmodic effect. When it is taken, the receptors of the nasal, oral cavity and pharynx are irritated. The signal coming from them to the brain reduces the excitability of the subcortical structures of the brain and enhances inhibitory processes.
• Phenobarbital is a popular ingredient that was widely used until recently. This substance is part of such drugs common in the CIS as Corvalol and valocordin, as well as foreign luminal. The reason for limiting its circulation today was its inclusion in the list of narcotic, psychotropic drugs. Low doses of phenobarbital calm, large - have a hypnotic and anticonvulsant effect.

1. Auxiliary components:

• Peppermint oil - due to its ability to irritate the receptors of the walls of organs, it can relieve spasms, dilate blood vessels, promote the removal of bile, and also has an antiseptic effect.
• Hop cone oil - has a multifaceted effect. Its active ingredients contribute to the release of bile, urine, help fight inflammation, regulate water-salt metabolism and have a calming effect. In addition to valocordin, hop cones are part of Novopassit.
• Ethyl alcohol 96%.
• Water.

Indications for use Valocordin

As an independent remedy or one of the components of the course of treatment, Valocordin is prescribed for:

• Early stages of arterial hypertension.
• Tachycardia.
• Pain in the region of the heart.
• With sleep disorders associated with trouble falling asleep.
• Nervous states.
• Hypochondria.
• Increased irritability.

This medication is used as a component of complex therapy for diseases that are accompanied by spasms of the muscles of the digestive tract. For example, it is prescribed to patients with biliary or intestinal colic.

Contraindications

This drug can not be prescribed to people with hypersensitivity to any of the components of the drug, as well as to patients with severe disorders of the kidneys and liver.

Due to its ability to depress the nervous system, Valocordin is prescribed with caution to patients who drive a car or engage in any activity that requires a quick reaction and concentration.

How to use Valocordin

Valocordin is sold exclusively in the form of drops that are taken internally before eating. Before taking them, they must be dissolved in a small amount of clean water.

The standard treatment regimen provides for 2 or 3 times the drug. A single dosage for adults is 15-30 drops, for a child - 3-15 drops per day. The duration of the therapeutic course is determined by the doctor.

Drug interactions of Valocordin with other drugs

It is not recommended to simultaneously prescribe valocordin and methotrexate, since in this case the side effects of the latter will be more pronounced. It must also be remembered that valocordin enhances the effect of drugs with similar properties. These include:

• sleeping pills;
• injections for local anesthesia;
• painkillers.

In turn, drugs containing valproic acid derivatives, as well as drugs that depress the nervous system (for example, doxylamine), potentiate the work of valocordin.

Phenobarbital affects the functioning of the liver. Therefore, this substance can reduce the effectiveness of drugs, the cycle of transformations in the body of which affects this organ.

Side effects

The negative effects of treatment with these drops are minor. First of all, it is drowsiness, decreased ability to engage in activities that require increased concentration of attention, dizziness. Individuals may develop allergic reactions. In this case, the course of therapy is recommended to be interrupted.

Phenobarbital and bromine, which is part of ethyl bromisovalerianate, have the ability to accumulate in the body. Therefore, a long course of treatment can lead to addiction and bromine poisoning. This may be evidenced by depression, detachment from reality, inflammation of the mucous membrane of the eye, runny nose, hemorrhagic diathesis, problems with coordination.

The appointment of Valocordin during the period of gestation and lactation

According to the instructions, the drug can be shown to expectant mothers only in certain cases when it is not possible to replace it with an analogue or the health benefits of the mother outweigh the likely risk to the child. For the period of treatment, it is necessary to interrupt breastfeeding.

The price of Valocordin and its analogues

The cost of even the original tool is small. The price range of 20 and 50 ml bottles is and respectively. But its counterparts are even cheaper:

What is the difference between Valocordin and Valocordin-doxylamine (VD)

Many people are misled by the presence of the word "valocordin" in the name of the second medicine. In fact, this is the only complete similarity between the two drugs. The active substance in the composition of the VD is doxylamine succinate, the remaining components perform an auxiliary function.

Like its namesake, VD has a hypnotic and sedative effect, but its mechanism is fundamentally different. It does not irritate, but blocks the histamine-H1 receptors of the ethanolamine group. Due to the difference, this medicine can be prescribed to combat allergies, itching. And when combined with other medicines - for colds, coughs.

Prohibition of Valocordin and its analogues

In our country, this drug is very popular as a cure for heart disease. But upon careful reading of our article, and for advanced users of the instructions, the reader will notice that none of the components of valocordin in any way affects the functioning of the heart. Why is it not the first generation of our fellow citizens who intensively heals their hearts? The fact is, this medication helps to fight the symptoms that accompany many cardiopathologies: anxiety, pain in the heart, tachycardia.

Also, magic drops make it possible for a person to forget a sound sleep and have a good rest. At the same time, general well-being improves, but heart problems remain and imperceptibly gradually progress. Moreover, it becomes more difficult for the doctor to analyze the patient's history, since many of the characteristic signs are masked by taking drops.

Above in the article, we mentioned that one of the main active substances, when taken for a long time, forms addiction, and the second leads to the accumulation of bromine and subsequent poisoning. A person with an ingrained habit of using the drug gradually ceases to receive the expected effect from the recommended doses and begins to exceed them. According to official statistics, every year about 50 people with signs of phenobarbital poisoning are admitted to the emergency department of St. Petersburg alone.

Against the background of all of the above, the fact that the favorite of the domestic consumer and its analogues is prohibited for sale in America, as well as in a number of European countries, does not look shocking. Interestingly, the manufacturer himself, Germany, also falls into this list. Let's say more, for more than a decade, phenobarbital derivatives have been dispensed without a prescription only in the CIS countries.

It is hard and necessary to give up the usual, incredibly cheap, but far from safe drops. Fortunately, modern medicine has something to offer in return.

If a person has a need to use Corvalol, but for any contraindications it is not suitable, the treatment is replaced with an analogue.

Corvalol's analogs

Corvalol itself is used as a sedative. Some take it instead of sleeping pills. But long-term use can reduce the effectiveness of the drug, a lot of bromine also accumulates in the body.

There are drugs that have a similar structure. These include Corvalol-MFF.

Similar drugs that have the same mechanism of action:

• Barboval - capsules;
• Bellataminal - tablets;
• Adonis-bromine - tablets;
• Valemidin - drops;
• Valeodikramen - drops;
• Valocordin - drops;
• Valoserdin - drops;
• Karniland - drops;
• Kliofit - elixir;
• Corvaldin - drops;
• Kravaleon - drops.

These drugs differ in composition, but perform the same functions. Such a number of analogs allows you to choose a course of treatment individually. No need to try to do it yourself: especially if the patient has chronic diseases.

Preparations include synthetic substances or natural ingredients.

Based on the composition, the drug for treatment will be selected.

Each of these drugs has contraindications and side effects.

Contraindications are such factors:

1. Patients under 18 years of age.
2. Low pressure.
3. Alcohol intake.
4. Allergy to any of the components.
5. Brain injury.

These are the main contraindications that are fundamental when choosing a method of treatment. Nevertheless (even if none of the factors are present), funds can be used for a certain period, and not taken constantly.

natural preparations

Along with drugs, Corvalol can be replaced with herbs or collections from them. The use of herbal remedies can last quite a long time. In this case, there is no accumulation of harmful substances in the body.

One of the most common is the herb valerian.

These drugs have a sedative effect, relieve pain, normalize the work of the stomach and heart, lower blood pressure.

Another doctor may recommend taking drops with valerian and lily of the valley. Sometimes a drug is used with the addition of adonis and sodium bromide. In some cases, tincture of hawthorn, motherwort, peony is recommended. It should be used strictly for its intended purpose, so as not to become an addiction.

Herbal preparations have sedative properties:

1. Sedative collection number 2.
2. Calming collection number 2.
3. Calming collection number 3.
4. Fitosedan No. 2.
5. Fitosedan No. 3.

The doctor will select the most suitable drug for the patient so that the effect is noticeable.

Natural based products:

1. Calm down.
2. Phytorelax.
3. Novo-Passit.
4. Fito Novo-Sed.
5. Liquid hop extract.

It must be remembered that even natural preparations should be used only after consulting a specialist.

Sedatives

Experts distinguish a group of sedative drugs. Some of them are similar in their properties to Corvalol. These can be herbal and chemical based products. They are able to give sedation without a hypnotic effect. These drugs are often prescribed to older people. They stabilize the work of the central nervous system, normalize natural sleep. The most popular components of these medicines are valerian, motherwort, mint and bromides.

When can these drugs be prescribed:

• additionally when using local anesthesia;
• in the treatment of heart disease;
• in case of overwork and overstrain;
• with insomnia;
• when feeling anxious;
• in the premenopausal period and with menopause;
• with general weakness;
• in a stressful situation.

Not all sedatives can replace Corvalol. But many are very similar in properties. Therefore, patients with contraindications can be offered a replacement, which is selected individually.

When choosing a doctor, consider:

1. The general health of the patient.
2. Age.
3. The presence of pathologies and chronic diseases.
4. Tolerance of any substances.

But when used properly, they help endure pain and suffering. If it is impossible to take Corvalol analogues can replace it. The choice is made only by a specialist.

Corvalol - instructions for use, reviews, analogs and formulations (tablets, drops or tincture) of a drug for the treatment of neurosis and irritability (sedative or sedative) in adults, children and pregnancy. Compound

In this article, you can read the instructions for using the drug Corvalol. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Corvalol in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Corvalol in the presence of existing structural analogues. Use for the treatment of neurosis and irritability (sedative or sedative) in adults, children, as well as during pregnancy and lactation.

Corvalol is a combined preparation, the action of which is due to the properties of its constituent substances. It has a sedative and antispasmodic effect. Facilitates the onset of natural sleep.

Ethyl bromisovalerianate (ethyl ester of alpha-bromisovaleric acid) has a sedative (similar to the effect of valerian) and antispasmodic effect, due to irritation mainly of the receptors of the oral cavity and nasopharynx, a decrease in reflex excitability in the central parts of the nervous system and an increase in inhibition in the neurons of the cortex and subcortical structures of the brain, and as well as a decrease in the activity of the central vasomotor centers and a direct local antispasmodic effect on smooth muscles.

Phenobarbital enhances the sedative effect of other components, helps to reduce the excitation of the central nervous system (CNS) and facilitates the onset of sleep.

Peppermint oil has a reflex vasodilating, antispasmodic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the "cold" receptors of the oral mucosa and reflexively expand mainly the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the mucous membrane of the gastrointestinal tract (GIT), increasing intestinal motility.

Peppermint oil + phenobarbital + alpha-bromoisovaleric acid ethyl ester + excipients.

As a sedative and vasodilator:

• functional disorders of the cardiovascular system;
• neurosis-like states, accompanied by increased irritability;
• sleep disorders;
• tachycardia;
• states of excitation with pronounced vegetative manifestations.

As an antispasmodic:

Instructions for use and dosage

The dose is set individually. Take orally, before meals, drink water. Adults are usually prescribed 1-2 tablets 2 times a day. With tachycardia, a single dose can be increased to 3 tablets. The maximum daily dose is 6 tablets.

The duration of the use of the drug Corvalol is determined by the doctor individually.

• drowsiness;
• dizziness;
• slow heart rate;
• decreased ability to concentrate;
• allergic reactions;
• the occurrence of drug dependence, addiction, "withdrawal" syndrome, as well as the accumulation of bromine in the body and the development of bromine phenomena (with prolonged use of the drug).

• hypersensitivity to the components of the drug;
• severe impairment of kidney and / or liver function;
• lactation period (if necessary, use during lactation should decide whether to stop breastfeeding);
• pregnancy;
• age up to 18 years (efficacy and safety not established);
• lactase deficiency;
• lactose intolerance;
• glucose-galactose malabsorption (the drug contains lactose).

Use during pregnancy and lactation

Contraindicated in pregnancy and during breastfeeding.

There is no experience of using the drug in children under 18 years of age.

During the use of the drug should not drink alcohol.

It is recommended to refrain from engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (including driving vehicles and working with complex mechanisms).

Drugs that depress the central nervous system enhance the effect of the drug.

Phenobarbital (an inducer of microsomal oxidation) may reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin, glucocorticosteroids, oral contraceptives); enhances the action of local anesthetics, analgesics and hypnotics. The drug enhances the toxicity of methotrexate.

The effect of Corvalol is enhanced by the use of valproic acid preparations.

Corvalol's analogs

Structural analogues for the active substance:

Analogues according to the mechanism of action (sedation):

• Adonis bromine;
• Balm Muscovy;
• Barboval;
• Bellataminal;
• Hawthorn tincture;
• Bromenval;
• Valemidin;
• Valeodicramen;
• Valerian tincture ("valerian");
• Valocordin;
• Valoserdin;
• Doppelgerz Vitalotonic;
• Doppelhertz Melissa;
• Karniland;
• Kliofit;
• Klosterfrau MELISANA;
• Corvaldin;
• Cravaleon;
• Landyshevo-valerian drops;
• Landyshevo-valerian drops with adonizide and sodium bromide;
• Landyshevo-motherwort drops;
• Lotusonic;
• Novo-Passit;
• Passifit;
• Peony tincture;
• Motherwort tincture;
• Sedative collection No. 2;
• Sedoflor;
• Sleepex;
• Songa Knight;
• Calming collection No. 2;
• Calming collection No. 3;
• Calm down;
• Fito Novo-Sed;
• Phytorelax;
• Fitosedan No. 2 (sedative collection No. 2);
• Fitosedan No. 3 (sedative collection No. 3);
• Hops infructescence;
• Hop extract liquid.

Analog drops Corvalol

Manufacturer: Marbiopharm (Russia)

Analogues of the drug Corvalol

An analogue is more expensive from 24 rubles.

Manufacturer: Farmak (Ukraine)

An analogue is more expensive from 27 rubles.

Manufacturer: Moscow Pharmaceutical Factory (Russia)

An analogue is more expensive from 119 rubles.

Producer: Krevel Moyselbach GmbH (Germany)

Release forms:

• Fl. 20 ml; Price from 133 rubles

When and how to take Corvalol tablets

Many people know that if a person is very nervous or his heart has a sharp pain, you can dissolve a few drops of Corvalol in water and drink it to calm down. This is one of the most popular drugs that is in any pharmacy. But the drug is available not only in liquid form, but also in tablet form, which is convenient for use in certain situations. For drops and Corvalol tablets, the instructions for use are approximately the same, since the drugs have the same effect and differ only in their form.

Corvalol: composition of the tablet

Although the form of the drug in drops is more popular, tableted Corvalol is no worse, and it is even more convenient to use it. The blisters contain round flat tablets of almost white color. Inside each dose of the drug contains a combination of the following substances:

• 580 mcg of oil derived from peppermint. This substance has a pronounced antispasmodic, antimicrobial and choleretic effect. Once in the oral cavity, it begins to irritate the receptors, which ultimately expands the blood vessels of the heart or brain. In addition, natural peppermint oil is used to treat flatulence, as it increases gastrointestinal motility.
• 7.5 mg phenobarbital. This is one of the most famous sedative components. It is used here to enhance the calming effect of all other substances. The agent reduces excessive overexcitation of the nervous system and causes the patient's natural desire to fall asleep.
• 8.3 mg alpha-bromoisovaleric acid derivatives. This is another effective sedative that also has an antispasmodic effect.

Thus, taking into account the individual actions of the components of the tablets, the drug acts as a sedative, having an additional moderate antispasmodic effect. In addition to the main substances, the tablet also contains auxiliary components that fill the dosage form.

Corvalol tablets: what helps

Due to the fact that the drug has a combined composition, it can be used in various cases. The most relevant use of Corvalol for the following indications:

• pathology of the heart and blood vessels;
• sleep problems;
• tachycardia;
• frequent neuroses, psychological breakdowns;
• increased irritability of the patient;
• excitation of the patient with strong vegetative manifestations;
• severe spasms of the intestines;
• small spasms of the coronary vessels.

The drug acts quite gently and has a more symptomatic effect. That is why it is used in self-treatment before contacting a doctor. The tool will calm the nerves, expand the blood vessels, put the heart in order.

The drug is most popular in liquid form, so many do not even know that it is also available in the form of tablets. Usually, users know the number of drops of Corvalol for various situations. But what about the pills?

Tablets are used orally, but a more effective method of application is sublingual. For this, the medicine is placed under the tongue and it is expected to dissolve completely.

Each patient may have their own dosage, which is determined by the doctor. As a rule, the drug is taken under one tablet three times a day. If the vasospasm occurs abruptly, the heartbeat quickens, the number of tablets can be increased even up to three.

You can take pills regardless of the diet. A maximum of 6 tablets per day is allowed, no more. As a permanent remedy, Corvalol can only be prescribed by a doctor. If you use it for self-treatment, a single application is enough.

There are special warnings for drivers. The drug depresses the nervous system and causes the effect of inhibition. It is contraindicated for anyone who needs increased concentration.

The speed of action of Corvalol

Although the drug enters the stomach in tablet form, it is absorbed rather quickly, since all components have a very high bioavailability. Usually, minutes are enough for all substances to enter the bloodstream and begin to act. The effect of the drug persists for 6 hours, if other drugs with barbituric acid have not been taken before.

In order to accelerate the onset of the therapeutic effect, the drug is placed under the tongue. Then the expressed changes can be 10 minutes after ingestion.

Why pills are better than drops

Many are so accustomed to drops that they do not see the benefits in other dosage forms. In fact, the therapeutic effect of liquid and tablet Corvalol is the same. But tablets are better because they do not have an alcohol smell. In the rest (speed of assimilation, strength of action, duration of effect, etc.), the drugs are identical, and the choice of one form or another depends on the patient's habits.

Possible drug overdose and side effects

Due to the fact that Corvalol contains barbiturates and other sedatives, an overdose of them is possible. The symptoms of this phenomenon are as follows:

• the central nervous system of the patient is sharply oppressed;
• sharply reduced blood pressure numbers;
• the general coordination of the patient worsens;
• there is weakness of the whole body and dizziness;
• possible apathy, depression.

First aid for overdose is to wash the stomach and intestines. After that, they struggle with the symptoms of the pathology that has arisen, eliminating subsequent negative effects.

But usually the drug is gently tolerated by patients, and they do not even experience side effects. If negative reactions occur, they may be as follows:

• allergic reaction, individual intolerance;
• dizziness;
• drowsiness, weakness;
• deterioration of attention, depression of cognitive functions;
• decrease in the number of heartbeats per minute.

In addition, among the side effects, addiction and dependence on the drug are distinguished. After discontinuation of the drug, new side effects appear. This means that Corvalol cannot be abused and should be taken only when necessary.

Contraindications

First of all, you need to understand whether Corvalol can be pregnant and lactating. Experts do not recommend them to use it due to the presence of barbiturates in the composition. In addition, there are other contraindications:

• allergy to Corvalol components;
• individual intolerance and hypersensitivity;
• lactose intolerance in the body;
• liver or kidney disease.

In the instructions for use, among the contraindications, the age of up to 18 years is also indicated, since clinical trials for this age have not been carried out.

Corvalol is categorically contraindicated simultaneously with alcohol, since alcohol affects the functioning of the liver and changes the pharmacokinetics of the drug. It is also contraindicated to use the drug in conjunction with other sedatives.

Analogues

The combined use of medicinal substances of mint, phenobarbital and bromizovaleriates is very effective, so many manufacturers are developing their own analogues of Corvalol, which are sold under other names - Corvaltab, Carditab, Darvilol, etc. They may differ slightly in composition, but the principle of their action is similar.

In addition, there are a number of drugs with a different composition, but with a similar effect:

Do not forget that before you start taking any medication, you must consult a doctor.

🔻🔻List of the most effective analogues of Corvalol

Corvalol is a sedative, antispasmodic, herbal remedy that normalizes sleep and blood pressure (contains valerian extract, mint oil and hop cones) with the addition of phenobarbital in a solution of ethyl alcohol. The action of the drug is due to the combined activity of all components.

Corvalol is an over-the-counter remedy, however, its prescription must be made by a doctor, as there are certain contraindications to its use, as well as a number of side effects. In case of intolerance to the drug, the attending physician selects a substitute for Corvalol, based on the diagnosis and taking into account concomitant conditions.

The main analogues of Corvalol

Corvalol is a generic drug that has an absolutely similar composition as its original - Valocordin (Germany), but it is produced in the Russian Federation and costs an order of magnitude cheaper than its foreign substitute.

Due to the barbiturate present in it, Valocordin helps to reduce excessive motor activity, calms the nervous system, has a hypnotic effect, reduces pain of moderate intensity, lowers blood pressure. Valerian complements the sedative effect, and is also an antispasmodic. Peppermint oil improves blood supply to the myocardium, relieves pain, improves the patient's emotional mood.

The drugs of this group are shown for:

• tachycardia;
• sleep disorders;
• neurotic disorders;
• VSD of hypertonic type.

• with insufficiency of kidney or liver function;
• hypersensitivity to the components of the drug;
• with diseases and injuries of the central nervous system;
• during pregnancy.

Of the side effects, allergic reactions are possible, bromism with long-term treatment with high doses.

Medicines with a similar principle of action:

• Barboval in drops (Farmak);
• Valoserdin in solution (MFF);
• Valemidin liquid (Pharmamed);
• Bellataminal tablets (Vilar), etc.

All these drugs differ in composition, but in general they consist of substances of plant origin and the indications for their use are the same as for Corvalol and Valocordin.

The contraindications are the same, in addition, they are not prescribed for children under the age of 18 and with severe hypotension.

herbal remedies

Herbs and plant preparations can also serve as a replacement for Corvalol. Unlike drugs produced by pharmaceutical factories, infusions and teas do not have such a large concentration of active substances and can be taken in short courses, but for a longer time. Their action does not develop so quickly, and the effect is much softer.

Valerian

The sedative effect of valerian has been known for a long time, and to this day it is the most popular herbal sedative. In the mind of modern man, the words "valerian" and "sedative" are synonymous. The advantages of using it are that even long-term use of it is not addictive, does not have a detrimental effect on the central nervous system. It can be used both as a monotherapy and in combination with other herbs for a faster and more pronounced effect.

Valerian is used both in the form of vegetable raw materials (ground pieces of rhizomes), and in the form of tincture and extract in the form of tablets of 20 mg.

Chamomile (complements a sedative effect, relaxes muscles), Ivan tea (relieves headaches and helps with insomnia), St. John's wort (relieves increased anxiety, relieves pain and fights inflammatory processes in the body), thyme (calms, improves immunity).

Examples of sedative fees:

• Soothing collection No. 1 (wormwood, adonis, valerian, mint, Ivan tea).
• Soothing collection No. 2 (yarrow, fireweed, chamomile, motherwort, St. John's wort).
• Soothing collection No. 3 (oregano, lemon balm, valerian, thyme, milkwort).
• Soothing collection No. 4 (hops, oregano, valerian, chamomile, St. John's wort).
• Soothing collection No. 5 (oregano, chamomile, mint, yarrow, motherwort).

Indications for the use of analogues of Corvalol of plant origin:

• in diseases of the heart and blood vessels with a tendency to arterial hypertension, coronary heart disease;
• with nervousness, anxiety, overwork, stress;
• in violation of falling asleep;
• during premenopause and menopause in women.

All medicines mentioned in this article are sold in pharmacies without a prescription. Exact therapy can only be selected by the attending physician, who understands the causal relationships of the symptoms and conditions that arise. This is also important in order not to miss a more serious diagnosis.

Corvalol tablets: instructions for use

Corvalol tablets - a sedative drug with an antispasmodic effect

The form of release of the drug, its composition and packaging

Corvalol is available in the form of white tablets with minor inclusions. The shape of the tablets is round, flat, somewhat beveled to the edge.

1 tablet of Corvalol contains 850 micrograms of peppermint oil, 7.5 mg of phenobarbital and 8.2 mg of α-bromoisovaleric acid ethyl ester. The composition also includes additional substances: starch, lactose, MCC, magnesium stearate, beta-cyclodextrin.

Tablets are enclosed in a blister of 10 pieces. Blisters of 2 or 10 pieces are enclosed in cardboard packs with the appropriate marking.

Mechanism of action

Corvalol tablets is a combined drug and its effect is determined by its constituent components. The drug has a calming effect, relieves spasms. Promotes natural sleep.

Ethyl bromisovalerianate has a calming effect and relieves spasms, due to the reflex effect on receptors located on the mucous membrane of the oral cavity and pharynx. The substance reduces the activity of centers in the cerebral cortex, affects neurons, enhancing the processes of inhibition.

Phenobarbital potentiates the sedative effect of other components and reduces excitability in the central nervous system, promotes the transition to sleep.

Peppermint oil has a vasodilating effect, relieves spasm, has a choleretic effect and is an antiseptic. The mechanism of action is associated with the ability of the oil to dilate blood vessels, acting on receptors in the oral mucosa. Thus, dilatation occurs mainly in the vessels of the heart and brain. Peppermint oil enhances the peristalsis of the gastrointestinal tract and helps to reduce the phenomenon of flatulence.

• neurosis-like state
• irritability,
• sleep disturbance,
• cardiopalmus,
• state of overexcitation
• intestinal spasm.

Corvalol tablets should not be taken if the patient has:

• Severe kidney and/or liver dysfunction
• breastfeeding period
• Individual intolerance to the ingredients of the drug
• Pregnancy period
• Age under 18
• Lactose intolerance with lactase deficiency.

How to use

The dose of the drug is set individually for each patient. It is recommended to take a Corvalol tablet before meals, drink plenty of water. The dose is usually 1 tablet 2 times a day. With a rapid heartbeat, take 3 tablets per day. A maximum of 6 tablets can be taken in 24 hours.

The duration of the use of tablets is set individually.

Symptoms of an overdose of Corvalol tablets

Taking an overdose is accompanied by the following symptoms: severe sedation, depression of the central nervous system, hypotension, weakness, dizziness, bromine intoxication - a depressive state, inflammation of the conjunctiva and nasal mucosa, impaired orientation in space.

Therapy: withdrawal of the drug, gastric lavage, intake of sorbents, elimination of symptoms. With severe depression of the central nervous system - analeptics (sodium caffeine benzoate, nikethamide).

Interaction of Corvalol tablets with other drugs

Drugs that promote CNS depression potentiate the effects of Corvalol.

Phenobarbital, which is part of Corvalol, is an inducer of the system of microsomal liver enzymes, which can affect the metabolism of those drugs that pass through the liver.

Valproic acid enhances the pharmacological effects of Corvalol.

Taking Corvalol tablets during pregnancy and lactation

The drug is contraindicated in pregnancy and breastfeeding.

Side effects

Taking Corvalol tablets may be accompanied by a number of adverse reactions that quickly disappear after a dose reduction or discontinuation of the drug. These include: sleep disturbance, bradycardia, dizziness, allergies, impaired concentration, dyspepsia.

Long-term use of Corvalol is accompanied by the emergence of dependence, the presence of a "withdrawal" syndrome and bromine poisoning.

How to store

Corvalol tablets should be stored in a dark place at a temperature range from 15 to 25 0 C, no more than 2 years from the date of release of the drug. Keep away from children.

Terms of dispensing from pharmacies

Corvalol tablets belong to the list of over-the-counter drugs; to purchase it at a pharmacy, there is no need to present a doctor's prescription.

special instructions

Corvalol tablets can only be used from the age of 18, as there is no evidence of the safety of taking the drug by a younger category of patients.

You should not be engaged in driving a car or other types of work that require increased attention and reaction speed, since Corvalol reduces the speed of psychomotor reactions.

Corvalol should not be taken in severe liver and/or kidney dysfunction.

Long-term continuous use of the drug should be avoided due to the risk of bromine intoxication.

Analogues of Corvalol tablets

Drugs with a similar composition that can replace Corvalol tablets include Corvaltab tablets, Darvelol drops, Carditab tablets.

Corvalol tablets price

The average cost of Corvalol tablets is 20 pcs. in pharmacies in Moscow is RUB.

Instructions for use Corvalol

Proven for countless generations, Corvalol is the most well-known sedative drug. In addition, it has a beneficial effect on heart tone and helps relieve muscle spasm. The tool has a complex effect on the body, and is also widely used for insomnia and neurosis of various origins. Instructions for the use of this drug are presented in our article.

Composition and pharmacological properties

The effect of the drug is largely due to the optimally selected composition. It is in many ways similar to another similar drug in action - valocardine. Corvalol alcohol solution contains the following important components.

Composition and action of Corvalol:

1. Ethyl alcohol alpha - bromizovaleric acid has a calming and antispasmodic effect. By irritating the nerve receptors of the oral cavity, it helps to slow down the reflex excitation of the central nervous system. The antispasmodic effect is directed to the muscles of smooth muscles.
2. Phenobarbital helps to reduce the excitation of the cerebral cortex. This is achieved due to the smooth regulation of blood pressure and the removal of spasm of the walls of blood vessels. This component has a calming and even tranquilizing effect, the intensity of which depends on the dosage of the drug. Peppermint oil contains esters in high concentrations that stimulate the prostate function of the intestine and provide a slight choleretic effect. In addition, peppermint oil can expand the vessels of the heart and brain. All this has a positive effect on the activity of smooth muscle muscles.

Corvalol has a high absorption rate. When taken orally in the sublingual region, the effect occurs after 15-20 minutes. The duration of exposure is determined individually and usually ranges from 3 to 6 hours. For the fastest relief, you can keep the drops in your mouth, then the effect is noted already 5 to 10 minutes after ingestion.

Release form and cost of funds

Traditionally, drops of Corvalol are most often in demand. They are quickly absorbed in the digestive tract. They are sold in opaque glass bottles of 25 or 50 ml. The only drawback of this dosage form is the characteristic menthol smell, therefore, for ease of use, there is also a tablet form of the drug.

Corvalol tablets are sold in a cell pack of 10 pieces. The cost of the plate is from 22 rubles, and a standard bottle of drops can be purchased from 25 (for 25 ml) to 39 rubles (a bottle with a capacity of 50 ml). compared to analogues, this is a really inexpensive and effective sedative.

Indications for use

Corvalol refers to sedative and hypnotic drugs with a slight spasmodic effect. Before use, be sure to consult a doctor. Despite the fact that the tool is an invariable attribute of many home first aid kits, its effect is not so harmless. In some regions, Corvalol is classified as a drug with a psychotropic effect, and its sale is by prescription.

What helps Corvalol:

• With insomnia and other sleep disorders;
• Increased nervousness;
• Removal of uncomfortable symptoms in vegetative - vascular dystonia;
• Elimination of spasm of coronary vessels;
• Comprehensive treatment of tachycardia and other problems of the cardiovascular system;
• A sedative in various situations;
• Spasms of the intestines that arose on the "nervous" soil.

Corvalol is in almost every first aid kit, because it is an inexpensive and effective drug for relieving attacks of heart palpitations, neuroses and other uncomfortable conditions. It should be noted that regular use of this drug can have a cumulative effect, so the advisability of taking this drug must be agreed with the doctor.

For questions about the dosage and duration of taking this drug, it is best to consult with your doctor. It will help to exclude possible pathologies and correct the regimen for the use of the drug.

Typically, patients are prescribed the use of Corvalol 15 to 30 drops at a time three times a day. It is advisable to do this before meals, diluting the drops in a small amount of water. You can drip corvalol on a sugar cube or directly under the tongue. The absorption rate of the product is quite high, which guarantees the rapid removal of uncomfortable symptoms.

Contraindications

Reception of Corvalol is not possible if one or more of the above contraindications are detected. Be sure to take into account that the remedy is psychosomatic, which means that it cannot be used uncontrollably and for a long time.

In what cases can not Corvalol be used:

1. Individual intolerance to the drug:
2. Serious damage to internal organs, especially the kidneys and liver;
3. Heart failure in severe form;
4. Arterial hypotension (decrease in pressure level);
5. Diabetes;
6. myocardial infarction;
7. Existing drug or alcohol addiction.

Side effects after the use of Corvalol in the indicated amounts are extremely rare. Usually this is excessive drowsiness, headache or general weakness. On the part of the digestive tract, nausea or constipation may occur.

Use during pregnancy and lactation

Due to the lack of information on the conduct of trials of this drug during pregnancy and breastfeeding, Corvalol is not used for such patients.

Can children take corvalol

There are no clinical data on the effect of the active components of Corvalol on the children's body. That is why for patients under 16 years of age, it is not advisable to use this remedy.

Side effects and cases of overdose

Compliance with the doctor's prescriptions for the dosage and duration of the course of taking Corvalol does not always guarantee an excellent result. Usually, with an overdose of the drug, the following negative reactions of the body occur.

What is fraught with an overdose:

• Respiratory depression, shortness of breath and bronchospasm;
• Heart rhythm disturbances;
• A sharp drop in blood pressure;
• General weakness, up to loss of consciousness;
• Nausea and vomiting;
• Lowering body temperature to critical values;
• Confusion of consciousness, decreased concentration.

Such conditions are especially dangerous with existing problems of the nervous system. Such patients need complete rest, as well as drug withdrawal to prevent other negative symptoms.

Compatibility with other medicines and alcohol

When using Corvalol to relieve uncomfortable symptoms, you should be very careful when taking the following drugs at the same time.

Drugs incompatible with Corvalol:

1. Sedative and hypnotic drugs.;
2. Analgesics and anesthetics (increases their effect on the body);
3. Valproic acid preparations;
4. cardiac glycosides;
5. indirect coagulants;
6. MAO inhibitors;
7. Non-steroidal anti-inflammatory drugs.

It should be noted that in no case should you combine the intake of Corvalol and alcohol. This combination can lead to damage to the brain, kidneys and liver due to a multiple increase in exposure to the drug.

Storage conditions

This drug belongs to list B. this means that the bottle should be protected from light, as well as temperature extremes (heating or freezing is not allowed). For convenience, you should save the original cardboard packaging, on which the date of opening of the product should be marked. Corvalol drops are stored no more than 2.5 years after the date of manufacture. The tablet form has a longer shelf life (5 years) and requires similar conditions.

The drug can not be used after the expiration date, and the storage place should be out of the reach of children.

special instructions

Corvalol should not be taken before doing work that requires increased attention and concentration. The active components of the drug have a sedative effect, so they can reduce the reaction. In addition, taking Corvalol has other features.

What you need to know:

• The course of treatment and dosage is determined by the attending physician.
• The drug can be addictive, in which its therapeutic effect is reduced. In addition, regular intake has a depressing effect on the nervous system and can create additional health problems.
• Uncontrolled intake can also lead to poisoning of the body with bromine. This leads to the development of a specific disease - bromism.
• Corvalol drops have a rather high content of ethyl alcohol, which may be unacceptable when used by patients with alcohol dependence.
• In old age, the rate of absorption of the drug slows down, so the doctor may prescribe a different dosage and regimen.

Corvalol does not eliminate the cause of discomfort, except in cases of mild tachycardia. If you suspect problems of the cardiovascular system or the central nervous system, the best option would be to go to a hospital for further examination.

In case of accidental overdose of the drug, it is urgent to induce vomiting (in a hospital setting, use the method of gastric lavage). Be sure to take absorbent drugs for a quick detoxification of the body. If symptoms of an overdose appear, it is best to seek professional medical help immediately.

Analogues

It is very difficult to find an identical composition of Corvalol, but there is a whole category of suitable pharmaceutical products with a similar therapeutic effect.

Valecard Barboval Valocordin Reladorm

It is very difficult to determine which drug is better and more effective. In addition to the different composition and active ingredient, this gradation does not take into account the diverse effects on the body. Only a specialist can compare well-known drugs: motherwort, valerian, hawthorn, peony and corvalol, taking into account the individual characteristics of the patient.

Corvalol, instructions for use of which are presented in our article, is one of the most famous sedatives. It has a beneficial effect on overall well-being, normalizes blood pressure and heart rate. In addition, Corvalol is an antispasmodic, which means it helps to relax the muscles of smooth muscles. Features of the use and dosage of Corvalol, as well as other nuances of using the drug, are discussed in the information provided.

Corvalol tablets: instructions for use, price, reviews and analogues

Corvalol is a drug that belongs to the group of sedatives. Although this medicine can be purchased without problems in Russian pharmacies, it is prohibited in countries such as the USA, Germany, and Norway. The restriction imposed on the sale of this drug is due to the fact that it contains the psychoactive compound phenobarbital. However, among Russians, this medicine is one of the most popular.

With pain in the heart, this drug helps to quickly eliminate the discomfort that has arisen. It must be used as prescribed by a doctor so that health problems are excluded during therapy.

Corvalol: composition and form of release

The drug Corvalol is available in the form of tablets and drops.

A pack of Corvalol tablets may contain 10, 30 or 50 pieces. The active compounds in Corvalol tablets are the following substances:

• ethyl ester of alphabromisovaleric acid 12.42 mg;
• phenobarbital 11.34 mg;
• mint oil 0.88 mg.

Corvalol in the form of drops is available in bottles of 25 and 50 ml. The composition of the drops contains the following substances:

• ethyl ester of alphabromisovaleric acid 2%;
• phenobarbital 1.82%;
• peppermint oil 0.14%.

Additional components are the following substances:

Indications for use

Corvalol is a drug that belongs to the group of sedatives and antispasmodics. Therefore, the purpose of this medication can be divided into two categories. As a sedative and vasodilator, it is prescribed for the following ailments:

• dysfunction of the cardiovascular system;
• a state of insomnia, especially if there is a violation of falling asleep;
• irritability;
• hypochondriacal syndrome;
• vegetative lability.

As an antispasmodic drug, Corvalol is prescribed for spasms of the muscles of the digestive tract, for example, with intestinal and biliary colic.

Method of application and dosage

Corvalol from other medicines has one difference, which consists in the method of application. Doctors prescribe it sublingually, that is, under the tongue. For adults, the drug is prescribed in a dosage of one tablet 2 times a day. If this is necessary, then a single dose can be increased to 3 tablets. Such a step is taken when diagnosing a patient with severe tachycardia or spasms of the coronary vessels.

The doctor determines the duration of the use of this drug. The duration of therapy largely depends on the clinical effect to be achieved, as well as the patient's tolerance of this medication.

Corvalol: contraindications

In the instructions for Corvalol, you can find a list of contraindications. You can also find out about this from reviews on the Internet. The main contraindications include the following:

• high sensitivity to the components present in the composition of this agent;
• low blood pressure;
• severe violation of the functions of the liver and kidneys;
• hepatic porphyria;
• severe heart failure;
• pregnancy and lactation.

In this article, you can read the instructions for using the drug Corvalol. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Corvalol in their practice are presented. A big request to actively add your reviews about the drug: did the medicine help or not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Analogues of Corvalol in the presence of existing structural analogues. Use for the treatment of neurosis and irritability (sedative or sedative) in adults, children, as well as during pregnancy and lactation.

Corvalol- a combined drug, the action of which is due to the properties of its constituent substances. It has a sedative and antispasmodic effect. Facilitates the onset of natural sleep.

Ethyl bromisovalerianate (ethyl ester of alpha-bromisovaleric acid) has a sedative (similar to the effect of valerian) and antispasmodic effect, due to irritation mainly of the receptors of the oral cavity and nasopharynx, a decrease in reflex excitability in the central parts of the nervous system and an increase in inhibition in the neurons of the cortex and subcortical structures of the brain, and as well as a decrease in the activity of the central vasomotor centers and a direct local antispasmodic effect on smooth muscles.

Phenobarbital enhances the sedative effect of other components, helps to reduce the excitation of the central nervous system (CNS) and facilitates the onset of sleep.

Peppermint oil has a reflex vasodilating, antispasmodic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the "cold" receptors of the oral mucosa and reflexively expand mainly the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the mucous membrane of the gastrointestinal tract (GIT), increasing intestinal motility.

Compound

Peppermint oil + phenobarbital + alpha-bromoisovaleric acid ethyl ester + excipients.

Indications

As a sedative and vasodilator:

• functional disorders of the cardiovascular system;
• neurosis-like states, accompanied by increased irritability;
• sleep disorders;
• tachycardia;
• states of excitation with pronounced vegetative manifestations.

As an antispasmodic:

• spasms of the intestines.

Instructions for use and dosage

The dose is set individually. Take orally, before meals, drink water. Adults are usually prescribed 1-2 tablets 2 times a day. With tachycardia, a single dose can be increased to 3 tablets. The maximum daily dose is 6 tablets.

The duration of the use of the drug Corvalol is determined by the doctor individually.

Side effect

• drowsiness;
• dizziness;
• slow heart rate;
• decreased ability to concentrate;
• allergic reactions;
• the occurrence of drug dependence, addiction, "withdrawal" syndrome, as well as the accumulation of bromine in the body and the development of bromism phenomena (with prolonged use of the drug).

Contraindications

• hypersensitivity to the components of the drug;
• severe impairment of kidney and / or liver function;
• lactation period (if necessary, use during lactation should decide whether to stop breastfeeding);
• pregnancy;
• age up to 18 years (efficacy and safety not established);
• lactase deficiency;
• lactose intolerance;
• glucose-galactose malabsorption (the drug contains lactose).

Use during pregnancy and lactation

Contraindicated in pregnancy and during breastfeeding.

special instructions

There is no experience of using the drug in children under 18 years of age.

During the use of the drug should not drink alcohol.

It is recommended to refrain from engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (including driving vehicles and working with complex mechanisms).

drug interaction

Drugs that depress the central nervous system enhance the effect of the drug.

Phenobarbital (an inducer of microsomal oxidation) may reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin, glucocorticosteroids, oral contraceptives); enhances the action of local anesthetics, analgesics and hypnotics. The drug enhances the toxicity of methotrexate.

The effect of Corvalol is enhanced by the use of valproic acid preparations.

Corvalol's analogs

Structural analogues for the active substance:

• Corvalol-MFF.

Analogues according to the mechanism of action (sedation):

• Adonis bromine;
• Balm Muscovy;
• Barboval;
• Bellataminal;
• Hawthorn tincture;
• Bromenval;
• Valemidin;
• Valeodicramen;
• Valerian tincture ("valerian");
• Valocordin;
• Valoserdin;
• Doppelgerz Vitalotonic;
• Doppelhertz Melissa;
• Karniland;
• Kliofit;
• Klosterfrau MELISANA;
• Corvaldin;
• Cravaleon;
• Landyshevo-valerian drops;
• Landyshevo-valerian drops with adonizide and sodium bromide;
• Landyshevo-motherwort drops;
• Lotusonic;
• Novo-Passit;
• Passifit;
• Peony tincture;
• Motherwort tincture;
• Sedative collection No. 2;
• Sedoflor;
• Sleepex;
• Songa Knight;
• Calming collection No. 2;
• Calming collection No. 3;
• Calm down;
• Fito Novo-Sed;
• Phytorelax;
• Fitosedan No. 2 (sedative collection No. 2);
• Fitosedan No. 3 (sedative collection No. 3);
• Hops infructescence;
• Hop extract liquid.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases that the corresponding drug helps with and see the available analogues for the therapeutic effect.