Kvamatel for dogs is a drug to reduce the acidity of gastric juice. Instructions for use and reviews of Kvamatel for dogs Kvamatel injections for cats
Over the past decade, more and more animals have become accustomed to eating pelleted food. famous brands, which is sold in a specialty store. To cure the consequences of such a diet, veterinarians recommend taking medical drug"Kvamatel" is simply irreplaceable for cats.
General information about the drug
"Kvamatel" is a synthetic drug approved for use by humans and pets. Active components accelerate the process of regeneration of the affected gastric mucosa, remove trophic ulcers, accompanying inflammation and other health anomalies.
The drug has several forms of release, and one of them is a composition for preparing a lyophilisate, which is most often prescribed to a sick pet. Tablets are also in demand for oral administration, which the breeder must mix into the cat’s food. Nothing complicated, but to obtain a sustainable therapeutic effect, sometimes taking a single portion is enough.
"Kvamatel" is productively absorbed into the gastrointestinal tract, spreads its effect to the mucous membrane, and penetrates the systemic bloodstream. It reaches its maximum concentration after a quarter of an hour, and the resulting effect from a single serving lasts for 12 hours. After this, you need to repeat the dose and not stop until complete recovery.
This medication has a lot of analogues, but this does not reduce its demand among breeders of sick animals. Questionable self-medication is completely excluded, while clear recommendations from a specialist and the consistent action of the cat owner will help save the life of their four-legged friend.
Indications and contraindications
The drug is intended for stomach ulcers and gastritis, duodenum in domestic animals. It is allowed to be taken as a preventive measure if the cat constantly consumes granulated food without receiving normal food.
"Kvamatel" is a safe medicine that has its contraindications. Among these are individual intolerance to the components, pregnancy or lactation of the cat. In the absence of such medical restrictions, treatment can be started, but the daily dosage must be observed. Cases of overdose cannot be ruled out, although they are extremely rare in veterinary practice. It is also important to avoid side effects, otherwise the sick animal will become even worse.
If the choice fell on tablets, the sick animal will not even suspect anything if such a composition is mixed into the food. There are no specific taste qualities, appetite is not reduced, but healing effect focused and fast. The main thing is to spend your time on this activity. free time and crush the Kvamatela tablet into a fine powder.
If there is stomach bleeding, the medical drug "Kvamatel" is one of effective ways eliminate this quickly and in a timely manner pathological process. Such treatment is carried out in a hospital setting under the supervision of a specialist.
Features of application
If your cat or cat is sick, it's time to go full diagnostics animal body. If your health problem is ulcerative lesions of the gastric mucosa, you must immediately start taking the drug "Kvamatel".
Since the drug is productively absorbed into the gastrointestinal tract, it can be used during the next meal. So that the cat gets single dose completely, you must first crush the tablet and mix it with food. The medication demonstrates high effectiveness for stomach ulcers, while its effect for gastritis with impaired acidity is rather mediocre.
Duration intensive care is determined individually, but, on average, the course lasts up to 2-3 weeks. In the absence of positive dynamics, it is recommended to change the drug after 5-6 days. This should be a conscious decision by the doctor, an adequate choice of an analogue and clear recommendations to the breeder regarding the treatment of his injured pet.
Since a stomach ulcer is chronic disease, taking Kvamatel can significantly prolong the period of remission. In this case, it is necessary to take the drug in courses with a certain time interval. Nothing complicated, the main thing is to take such drug therapy as a rule.
Side effects and cases of overdose
It is not recommended to increase daily doses, otherwise the effect will be enhanced side effects. In this case, we are talking about signs of dyspepsia, flatulence, bloating, and loss of appetite. A sick animal behaves passively, does not ask to eat, and spends most of its time sleeping. Treatment is symptomatic, but it is recommended to start with correction daily dose and consultation with a veterinarian.
If the cat is in an “interesting position”, such therapy is not recommended. The problem must be supported, but not resorted to radical methods treatment. Despite its chronic course, gastric ulcers cause periodic relapses. During this period, the use of the drug "Kvamatel" is mandatory, and the doctor individually stipulates the method of use and daily dosage.
Drug interactions are not significant, so the medication may become part of complex treatment, or act as an independent medicinal product. In both cases, the desired effect will not linger and will pleasantly please the breeder.
As numerous studies show, “Kvamatel” adapts imperceptibly in the animal body, and if the dosage is observed, it does not disrupt the systemic digestion of a sick cat. There are known cases of complete healing of four-legged friends.
The medication is inexpensive, so every breeder of a cat with ulcers can afford to buy it. The price range varies between 100-200 rubles, and Kvamatel is sold in any pharmacy, including veterinary.
Prevalence of gastrointestinal diseases in Lately increases not only among people, but also among animals. The main cause in both cases is considered to be poor nutrition; pets that constantly eat dry food are at risk.
Before acceptance this drug consultation with a veterinarian is required
The mechanism of action of the drug is to reduce the production gastric juice, at the same time the acidity and the proportion of the enzyme component decreases. The main advantage of the drug is that it does not affect absorption during meals, which is very important. Many pet owners know firsthand how difficult it is to give your pet pills. Quatemal has no taste or smell and is easy to hide in food. It is also worth noting that medication can only be given after consultation with a veterinarian, important role compliance with the dosage plays a role.
Indications for prescribing the drug
Kvatemal is recommended for use for ulcerative lesions of the stomach and duodenum. Indications also include situations where it is necessary to reduce the production and acidity of gastric juice, as well as the amount of gastric enzymes produced. Such a need may arise before the introduction general anesthesia before surgery, taking medication is considered an excellent preventive measure for the release of Airways stomach contents.
Kvamatel for cats is used for stomach ulcers.
Other indications:
- diagnosed gastric bleeding;
- non-peracid gastritis;
- ulcerative colitis.
Important: The drug is intended for both single and multiple use. It shows effectiveness during one-time attacks and during a long course of intensive therapy. We are actually talking about a universal medicine, the maximum concentration of the main components in the blood is achieved in an hour, the duration of action of the medicine is 12 hours.
Instructions for use and dosage of the drug for cats
The drug is available in tablets and powder for solution. Main active substance is famotidine, auxiliary components: povidone, corn starch, lactose, magnesium stearate, talc, colloidal anhydrous silicon.
In the absence of vomiting and nausea, the tablets are recommended to be taken orally. The standard dosage of tablets depends on the weight of the animal, 0.5-1 mg per 1 kg twice a day. The dosage of IV powder is calculated in the same way; the drug is also administered twice a day.
Contraindications and side effects
The drug is quite serious, so it should only be used as prescribed by a veterinarian.
The drug is contraindicated for use in cases of anacid or hypoacid inflammation of the stomach; in this case, it can lead to the painful death of the cat. The fact is that these types of gastritis are accompanied by a decrease in acidity and a weakening of the digestive properties of gastric juice. The digestion of food in the stomach becomes difficult, it simply begins to rot, which leads to Negative consequences. The same effects occur when the dosage is exceeded, so the dosage must be respected.
Side effects
In accordance with the instructions for use, the medicine may be accompanied by the following side effects:
- digestive system - pancreatitis, constipation, hepatitis, flatulence, vomiting;
- circulatory system - hypertension, hematopoietic disorders, bradycardia, arrhythmia, falling into a coma.
After long-term therapy with quatemal, you should stop taking it gradually; failure to comply with this recommendation can lead to severe gastritis and ulcers.
Important: It is also necessary to take into account that the drug has the property of blocking histamine receptors, therefore, the medication should be stopped during the period of allergy tests.
Conditions: shelf life and price
Excipients: colloidal silicon dioxide - 1 mg, magnesium stearate - 2 mg, K90 - 4 mg, sodium carboxymethyl starch (type A) - 6 mg, talc - 6 mg, corn starch - 56 mg, lactose monohydrate - 105 mg.
Film shell composition: red iron oxide - 0.012 mg, colloidal silicon dioxide - 0.088 mg, titanium dioxide - 0.288 mg, macrogol 6000 - 0.499 mg, sepifilm 003 - 6.613 mg (macrogol-40 stearate (type I) - 8-12%, microcrystalline cellulose - 35 -45%, hypromellose - 45-55%).
14 pcs. - blisters (2) - cardboard packs.
Film-coated tablets dark pink, convex, with "F40" engraved on one side; on the fracture, white or almost white.
| 1 tab. | |
| famotidine | 40 mg |
Excipients: colloidal silicon dioxide - 1 mg, magnesium stearate - 2 mg, povidone K90 - 4 mg, sodium carboxymethyl starch (type A) - 6 mg, talc - 6 mg, corn starch - 51 mg, lactose monohydrate - 90 mg.
Film shell composition: red iron oxide - 0.024 mg, colloidal silicon dioxide - 0.088 mg, titanium dioxide - 0.276 mg, macrogol 6000 - 0.499 mg, sepifilm 003 - 6.613 mg (macrogol-40 stearate (type I) - 8-12%, microcrystalline cellulose - 35 -45%, hypromellose - 45-55%).
14 pcs. - blisters (1) - cardboard packs.
pharmachologic effect
Histamine H2 receptor blocker. Suppresses secretion of hydrochloric acid, basal and stimulated by gastrin, histamine and acetylcholine, while the pH of the stomach contents increases and pepsin activity decreases.
Famotidine has little effect on liver microsomal enzymes.
After taking the drug orally, the effect occurs within 1 hour, the maximum effect is within 3 hours after administration, the duration of the effect ranges from 12-24 hours, depending on the dose.
Pharmacokinetics
Suction
Absorption is incomplete. Cmax is reached after 1-3 hours and is 0.07-0.1 mg/l. Bioavailability - 40-45%, increases with simultaneous administration food and decreases with simultaneous intake.
Distribution
Plasma protein binding is 10-20%. Penetrates through the placental barrier and through the BBB. Excreted in breast milk.
Metabolism
30-35% of the drug is metabolized in the liver to form S-oxide.
Removal
T1/2 of is 2.3-3.5 hours. After oral administration, 30-35% of famotidine is excreted unchanged by the kidneys.
Pharmacokinetics in special clinical situations
With CC<10 мл/мин T 1/2 может достигать 20 ч (требуется коррекция дозы).
Indications
- peptic ulcer of the duodenum and stomach in the acute phase, prevention of relapses;
- treatment and prevention of symptomatic ulcers of the stomach and duodenum (associated with taking NSAIDs, stress, postoperative ulcers);
- erosive gastroduodenitis;
- functional dyspepsia associated with increased secretory function of the stomach;
- reflux esophagitis;
- Zollinger-Ellison syndrome;
- prevention of recurrent bleeding from the upper gastrointestinal tract;
- prevention of aspiration of gastric juice during general anesthesia (Mendelssohn syndrome).
Contraindications
- pregnancy;
- lactation period;
- childhood;
- increased sensitivity to famotidine and other histamine H2 receptor blockers.
Carefully: renal or liver failure, liver cirrhosis with a history of portosystemic encephalopathy.
Dosage
Taken orally.
At peptic ulcer of the stomach and duodenum in the acute phase Kvamatel is prescribed in a dose of 40 mg 1 time / day before bedtime or 20 mg 2 times / day. If necessary, the daily dose can be increased to 80-160 mg. The duration of treatment is 4-8 weeks.
With the aim of prevention of exacerbations of gastric and duodenal ulcers Kvamatel is prescribed in a dose of 20 mg 1 time / day before bedtime.
At reflux esophagitis the initial dose is 20 mg 2 times / day; if necessary, the drug can be used at a dose of 40 mg 2 times a day.
At Zollinger-Ellison syndrome the initial dose is 20-40 mg every 6 hours; if necessary, the daily dose can be increased to 240-480 mg.
For prevention of aspiration of gastric juice during general anesthesia, Kvamatel is prescribed at a dose of 40 mg on the eve of surgery or in the morning on the day of surgery.
At renal failure, if CC<30 мл/мин or serum creatinine >3 mg/dL, the daily dose should be reduced to 20 mg or the interval between doses increased to 36-48 hours.
Side effects
From the digestive system: dry mouth, nausea, vomiting, loss of appetite; increased activity of liver transaminases, hepatocellular, cholestatic or mixed hepatitis, acute pancreatitis.
From the hematopoietic system: very rarely - agranulocytosis, pancytopenia, leukopenia, thrombocytopenia, bone marrow hypo- or aplasia.
Allergic reactions: urticaria, skin rash, itching, bronchospasm, angioedema, anaphylactic shock.
From the cardiovascular system: arrhythmia, bradycardia, AV block, decreased blood pressure.
From the nervous system: headache, dizziness, drowsiness, fatigue, hallucinations, confusion.
From the senses: decreased visual acuity, tinnitus.
From the reproductive system: with long-term use in high doses - amenorrhea, decreased libido, hyperprolactinemia, gynecomastia.
From the musculoskeletal system: myalgia, arthralgia.
Dermatological reactions: alopecia, acne vulgaris, dry skin.
Other: fever.
Overdose
Symptoms: vomiting, motor agitation, tremor, decreased blood pressure, tachycardia, collapse.
Treatment: gastric lavage, symptomatic and supportive therapy; hemodialysis.
Drug interactions
Due to the increase in the pH of the gastric contents, famotidine, when used simultaneously, reduces the absorption of itraconazole.
Antacids and sucralfate slow down the absorption of famotidine. You should observe a 1-2 hour break between taking these drugs.
When taking famotidine and drugs that inhibit bone marrow hematopoiesis simultaneously, the risk of developing neutropenia increases.
Famotidine increases the absorption of amoxicillin and clavulanic acid.
special instructions
The use of famotidine may mask the symptoms of stomach cancer, so before starting treatment with famotidine, it is necessary to exclude the presence of a malignant neoplasm.
Like all histamine H2 receptor blockers, if treatment is abruptly stopped, famotidine can cause withdrawal syndrome, so treatment is stopped, gradually reducing its dose.
In patients with impaired liver function, Kvamatel should be prescribed with caution and in lower doses.
With long-term treatment of weakened patients or patients under stress, bacterial damage to the stomach is possible with further spread of infection.
Kvamatel should be taken 2 hours after taking itraconazole or ketoconazole to avoid a significant decrease in their absorption.
Histamine H2 receptor blockers can inhibit the acid-stimulating effect of pentagastrin and histamine, so famotidine should be discontinued 24 hours before the test.
Histamine H2 receptor blockers may suppress the skin response to histamine, leading to false-negative skin test results. Therefore, before performing diagnostic skin tests to detect an immediate allergic skin reaction, famotidine should be discontinued.
During treatment, you should avoid consuming foods, drinks and other medications that may irritate the gastric mucosa.
Impact on the ability to drive vehicles and machinery
During treatment with famotidine, patients should be careful when driving vehicles and engaging in other activities that require increased concentration and speed of psychomotor reactions.
Pregnancy and lactation
The drug is contraindicated for use during pregnancy and breastfeeding.
For impaired renal function
Carefully: renal failure.
For liver dysfunction
Carefully: liver failure, liver cirrhosis with a history of portosystemic encephalopathy.
Conditions for dispensing from pharmacies
The drug is available with a prescription.
Storage conditions and periods
The drug should be stored out of the reach of children, protected from light at a temperature not exceeding 25°C. Shelf life - 5 years. Do not use after the expiration date stated on the package.
Owners of cats and dogs are increasingly noticing that their pets suffer from stomach and intestinal diseases. Illnesses arise due to increased acidity in the stomach. Kvamatel for cats helps to successfully fight this pathology. The drug is specially designed for the treatment of digestive system disorders.
Nature of action of the drug
Veterinarians believe that the main reason for the development of the disease is improperly organized feeding of cats. The risk group includes those animals that eat dry food every day without the addition of other products. We offer a description of how the drug acts on the animal body.
Kvamatel successfully blocks H2 type histamine receptors, reduces the intensity of the processes of hydrochloric acid production, thereby reducing the level of acidity of the juice produced in the stomach.
The medication effectively relieves the symptoms of the disease in cats and also reduces the production of acid in their bodies. It acts directly on the cause of the disease, which is why veterinarians most often prescribe the drug to their patients.
The drug has several positive properties:
- does not affect the functioning of internal organs and metabolic processes;
- does not reduce the amount of enzymes and hormones produced;
- the liver does not suffer while taking the medicine;
- has a therapeutic effect on the gastrointestinal tract within 60 minutes, the active substance remains active throughout the day;
- with the intravenous route of administration, Kvamatel will take effect after half an hour.
If an injection with Kvamatel is given in the evening, the medicine will suppress the production of hydrochloric acid all night, for 12 hours. In the morning the cat will feel relief.
The drug simultaneously reduces the secretion of gastric juice, excess enzymes and acidity. Absorption occurs regardless of meal time.
Owners know very well that it is not easy to use Kvamatel tablets for a cat; it is almost impossible to persuade him to eat the medicine. For convenience, the tablets need to be crushed and added to the food.. The medicine is odorless and tasteless, so the animal will not notice its presence in food.
The veterinarian must prescribe the medication and set the dosage.
Release forms
In pharmacies in Moscow and other cities you can buy both Kvamatel itself and its inexpensive analogue, Famotidine.
The manufacturer produces the drug in different forms.:
- standard tablets: Kvamatel 20 or Kvamatel 40, depending on the volume of the active substance;
- 10 mg tablets (called Kvamatel mini), where the active ingredient is present in small quantities;
- lyophilisate powder in ampoules for injections.
The package contains 28 tablets of 20 mg, 14 tablets of 40 mg and five ampoules of lyophilisate with solvent. The main active ingredient in the tablets is famotidine.
Indications
Kvamatel is used to treat ailments caused by increased acidity.
Indications for use of Kvamatel for cats:
- various digestive problems;
- stomach ulcer,
- gastritis;
- bleeding in the stomach;
- colitis.
The drug is also used during operations, as well as to prevent food particles from entering the respiratory tract from the stomach.
Lyophilisate and regular tablets are indicated for the treatment of diseases. Kvamatel mini is used for functional disorders. When there are no pathologies, 10 mg tablets are used to eliminate signs of increased acidity.
The medication is effective when taken once to relieve an attack, and can also be used for course therapy. This is a universal remedy.
Admission rules
The dosage of Kvamatel for a cat is calculated based on the cat’s body weight: up to 1 mg of the drug will be needed per 1 kg of weight. You need to take the medicine twice a day; it is better to give it to your cat during meals.
The dosage of the solution prepared from the powder is set in the same way. Kvamatel for cats is administered intravenously twice a day. Instructions for use Kvamatel for cats recommends taking tablets if there are no attacks of vomiting. It is not worth experimenting with Kvamatel, because not a single drug is absolutely harmless. Treatment with this medicine can be started after consulting a doctor.
Contraindications and side effects
The drug is prohibited for use in two types of gastritis:
- hypoacid, when the gastric mucosa is inflamed and the secretion of the glands is reduced;
- anacid, which is characterized by low acidity due to atrophy of stomach cells.
In both cases, the use of Kvamatel leads to the painful death of the cat. The same thing awaits your pet in case of an overdose, so you must strictly follow the veterinarian’s recommendations. It should be remembered that in case of inflammation of the gastric mucosa, Kvamatel is strictly prohibited. You cannot independently diagnose a cat and treat it at your own discretion, as this can lead to unpleasant consequences.
The instructions warn about the possibility of side effects.
These include:
- pancreatitis,
- flatulence,
- constipation,
- vomit,
- hypertension,
- cardiac arrhythmia,
- falling into a coma.
After a long course of treatment, Quatemal should be stopped gradually so as not to cause gastritis or ulcers.
By following these simple rules, you can provide the necessary medical care to your cat and normalize its condition.
In recent years, diseases of the gastrointestinal tract have become several times more common not only in humans, but also in their pets. Just like with humans, poor diet is to blame. If your cat has been on dry food all his life, then one day he may need Kvamatel for cats.
Without going into pharmacological details, this remedy allows you to reduce the secretion of gastric juice. In addition, at the same time the medicine significantly reduces its acidity and the mass fraction of the enzyme component. This allows you to reduce the negative effect of its action on the inflamed gastric mucosa. As you might guess, all this can be extremely useful in the treatment of ulcers.
With a single dose of the drug, its maximum concentration is reached in less than an hour, and the beneficial effect persists for approximately 12 hours. The huge advantage of this product over analogues is that food intake does not affect its absorption in any way. This allows cats to be given tablets directly during feeding (disguised in food) without worrying about the therapeutic effect.
In what cases is its use indicated?
Use is indicated for the duodenum. The drug can also be used in all cases where it is necessary to reduce the secretion of gastric juice, its acidity and the volume of secreted gastric enzymes. For example, this may be required before general anesthesia is required for surgery. This prevents stomach contents from being released into the airways. In addition, the drug can be used if gastric bleeding is diagnosed.
Read also: Quarantine after rabies vaccination in cats
Since the medicine reduces the acidity of gastric juice, it does not act so aggressively on damaged areas of the organ mucosa. Sometimes long-term use of the drug is required if the cat has an ulcer in the stomach or duodenum, which (despite treatment) tends to recur periodically.
Important Note
Quite often the medicine is prescribed for. But! Under no circumstances should you try to “write it out” yourself! The fact is that gastritis should be hyperacid! If you give Kvamatel to a cat suffering from hypoacid (or generally anacid) inflammation of the stomach, then you can simply kill it, and in a particularly sophisticated and painful way.
With these types of disease, the acidity and digestive ability of gastric juice is already greatly reduced, and if this medicine is given, then all the food that enters the gastrointestinal tract will not be digested at all. She will simply rot. You can guess the consequences yourself. However, the same results can be achieved if you feed Kvamantel to a cat with hyperacid gastritis constantly and in elephantine volumes. So the dosage of the drug is entirely under the control of the veterinarian! You don't have to calculate it!
Briefly about side effects
If you were not convinced by the facts described above, then perhaps overly caring owners will be “understood” by side effects:
- Unstoppable.