Choleretic drugs. List of choleretic drugs for stagnation of bile Which choleretic is better

Cholagogue drugs are needed for a bladder. They enhance bile formation, improve the tone of the ducts and bladder, and relieve spasms. Their effectiveness has been proven in atony of the organs of the biliary system, chronic diseases of the gastrointestinal tract. Due to possible allergic reactions and some contraindications, the gastroenterologist prescribes the medicine after examinations and diagnosis.

List of choleretic drugs: classification by action

With litholytic action

The best choleretic drugs that prevent the formation of calculi in the gallbladder or them contain ursodeoxycholic acid. It improves the quality of bile, lowering cholesterol, thereby destroying cholesterol stones. On the Russian pharmacy market you can buy:

• Ursofalk (Germany);
• Ursosan (Czech Republic);
• Ursoliv (Russia).

They contribute to the rapid elimination of toxins, cleanse the liver, so they are prescribed not only for gallstones, but also for inflammation and dyskinesia of the bile ducts.

Herbal products

With stagnation of bile, natural preparations with medicinal herbs are prescribed. They are recommended in the following cases:

• if there are contraindications for taking other medicines;
• when a mild effect on the organs of the hepatobiliary system is required;
• when complex therapy is needed.

Herbal preparations normalize bile formation, reduce the amount of cholesterol, reduce the risk of stones, increase the tone of the walls of the organs of the biliary system, and eliminate spasms. These plants include:

• corn columns with stigmas, they are produced in filter bags or in the form of an extract (Leovit);
• immortelle sandy is sold as part of choleretic tea, dry extract and Flamin preparation;
• common tansy is part of the collection Phytogepatol No. 3, the drug Tanacechol;
• artichoke, the leaves of which are the main component of the artichoke extract in tablets (Evalar) and the drug Hofitol.

The funds are characterized by a strong choleretic effect, but, like any herbal preparations, they often cause allergies. In order not to harm your health, you must first consult with a specialist.

In what cases do they drink cholagogues and when they are prohibited

The causes of bile stasis are:

• hereditary predisposition;
• congenital or acquired pathologies of the organs of the hepatobiliary system;
• pancreatitis, gastritis, stomach ulcer;
• the formation of stones;
• heart failure;

Alcohol abuse, fatty, spicy, fried foods, stress, self-medication provoke stagnation.

To suspect the stagnation of bile will allow the unpleasant problems that have arisen:

• belching, heartburn, nausea;
• stool disorders;
• loss of appetite;
• gravity .

Sleep is disturbed, general weakness, fatigue, sweating, plaque on the tongue appear.

The presence of these symptoms requires immediate treatment to a gastroenterologist. Based on the results of the examination, drugs are prescribed to improve the processes of digestion, ensuring a normal outflow of bile, eliminating its causes.

Among the contraindications are cirrhosis of the liver, diarrhea. Cholekinetics are not taken for cholelithiasis.

Indications for complex therapy:

• chronic diseases of the liver and organs of the biliary system (treated with choleretics, cholekinetics);
• dyskinesia of the bile ducts (treated with cholekinetics and other choleretic);
• congenital or acquired bending of the gallbladder (cholespasmolytics are prescribed);
• the presence of small stones in the bladder (recommend cholelitholitics).

Cholagogue drugs should not be drunk with exacerbations of chronic diseases of the liver, biliary tract, acute pancreatitis, stomach and duodenal ulcers, individual intolerance. Cholagogues are strictly prohibited for large or numerous stones.

Reception features

The doctor prescribes a choleretic treatment regimen. For example, the use of Allochol, Holenzim is recommended after meals, Hofitol, Odeston, Flamin - in 20-30 minutes. before meals. The duration of the course depends on the condition of the patient, the stage of the disease and ranges from 2 to 4 weeks.

During pregnancy

The use of cholagogue during pregnancy is possible only after consulting a doctor.

Some drugs are prescribed to pregnant women only for health reasons (Ursosan, Hologon, Odeston), they are not prescribed during lactation. With caution, under the supervision of a gastroenterologist, they drink Hofitol, Berberis-Homaccord, Besalol, No-shpu, Flamin, Holosas, Tanacehol.

Pregnant women take effective choleretic drugs Holenzym, Allochol, valerian extract and sorbitol without restrictions, according to the scheme prescribed by the doctor.

children

For children, Flamin is produced in granules packaged in sachets for a single dose: babies up to a year are given one sachet, with age their number is gradually increased, after 5 years they take 4 sachets.

Babies are prescribed Hofitol in solution (the dosage is determined by the doctor), from the age of 6, tablets are allowed. No-shpu for babies is crushed and dissolved in water.

Treatment of congenital or acquired pathologies of the biliary system in a child with choleretic agents is carried out with great care under the supervision of a specialist.

Some choleretic (Allochol, Holosas, Ursosan) and medicinal mineral waters are taken in small quantities from the age of 3, Odeston is prescribed after 7 years, Hologon - after 12.

For some diseases

Medicines for stagnation of bile are chosen depending on the diagnosis. So, choleretic drugs and with pancreatitis are prescribed different. Remedies for diseases of the digestive system are given in the table:

Disease	Group	Preparations
When the gallbladder is removed	Choleretics	Allochol, Odeston, Holosas
	Cholespasmolytics	Bellalgin, No-shpa
With pancreatitis	Choleretics	Allochol, Holenzim
	Combined	Odeston, Flamin
	litholithics	Ursosan
With giardiasis in adults	cholekinetics	Holosas, Mannitol, Berberis-Homaccord
	Cholespasmolytics	No-shpa, Papaverine, Besalol
At	Choleretics	Allochol, Holenzim
	Hydrocholeretics	Mineral water
	litholithics	Ursofalk, Ursoliv
Chronic diseases of the stomach and duodenum	Choleretics	Allochol, Hofitol
	Cholespasmolytics	Papaverine, No-shpa
	Combined	Odeston
	litholithics	Ursosan

Treatment of these pathologies should not be limited to choleretic drugs. For example, in the absence of a gallbladder, enzyme preparations and hepatoprotectors are additionally taken; with cholecystitis and pancreatitis, analgesics, anti-inflammatory drugs, are prescribed.

How to understand that the drug has begun to work

Cholagogue drugs with stagnation of bile act slowly. Even with a healthy lifestyle, refusal of alcohol, and all doctor's prescriptions, disturbing symptoms recede gradually:

• stool normalizes, constipation disappears;
• improves the color of feces;
• passes bitterness in the mouth;
• ceases to torment heartburn;
• appetite improves.

If the therapy was prescribed in a timely manner, after a course of treatment, discomfort in the right hypochondrium will gradually disappear, weakness will pass.

Folk remedies and foods with a choleretic effect

• ginger;
• calendula;
• turmeric;
• Birch buds;
• immortelle and others.

They are used both separately, for example, tea with ginger, and in collections. With oils and mineral water at home, a deep cleansing of the liver is carried out ().

Some have choleretic properties: beets, radishes, pears, parsley, celery, carrots, oranges. Fresh juices and salads are prepared from them. Vegetables do not lose their medicinal properties even after cooking.

Literature

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• Surgical diseases. Guidelines for the examination of the patient: Textbook / Chernousov A.F. etc. - M.: Practical medicine, 2016. - 288 p.
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Updated: 23.10.2018 11:22:05

Judge: Boris Kaganovich

*Overview of the best in the opinion of the editors of the site. About selection criteria. This material is subjective, is not an advertisement and does not serve as a guide to the purchase. Before buying, you need to consult with a specialist.

Digestion is a holistic process, but it is divided into parts that seem to be opposite and incompatible. So, the stomach is very acidic, and the duodenum is already alkaline. In order to reduce the acidity of the gastric juice that has entered the intestines, and neutralize the activity of gastric enzymes, and transfer the change in the phases of digestion from acidic to alkaline (intestinal), a special liquid called bile is produced in the liver.

Every day, about a liter of this fluid is formed and excreted from the body of an adult. The bile of a healthy person has a greenish or yellow color, it tastes extremely bitter. Once formed, it is transported through its own ducts to the vesica fellea, or gallbladder, where it is stored. After contraction of the smooth muscles of the gallbladder, it is released into the intestinal lumen as needed, taking part in digestion.

Bile also helps emulsify, or dissolve, fats in the intestines and prepare them for digestion. It improves intestinal motility, increases the production of digestive hormones. Its role in the binding and excretion of cholesterol and the breakdown product of hemoglobin contained in the blood is very important. It's called bilirubin. Since this substance is not able to be filtered through the renal glomeruli, bilirubin is excreted through bile and leaves the body with feces.

Most often in clinical practice, there are conditions associated with the slow formation of this fluid, with the difficulty of its entry into the small intestine, due to the development of cholelithiasis - stone disease, chronic inflammation of the bladder - cholecystitis and other pathology of the pathways that excrete bile. The resulting chemical or mechanical obstacles to the normal flow of bile into the intestines cause a number of painful symptoms.

This is discomfort in the abdomen on the right, bitterness, nausea, in severe cases, obstructive jaundice, bloating, discoloration of feces may occur. In order to normalize the passage of this important fluid, choleretic drugs are used. This rating included the most effective and frequently prescribed remedies from this list. Choleretic drugs differ in their mechanism and indications for their purpose. The review begins with the so-called choleretics.

Rating of the best choleretic agents

The best choleretic - choleretics: education stimulants

Means that stimulate the formation of bile from its precursors are natural, or true, synthetic, as well as herbal choleretic agents that have a bile-forming effect. True choleretics are often remedies of animal origin. The most popular choleretic agents from all subgroups will be listed below. Of these, Allochol is a true choleretic, Odeston is a synthetic remedy, and Holosas is a choleretic drug consisting of one plant component.

Allochol is perhaps the most popular and affordable "folk" choleretic medicine. This is a combined remedy, and Allohol contains dry cattle bile, dry nettle and garlic, as well as activated charcoal. All these components together give a stronger choleretic effect than just one bile. Allochol is able to increase the contractions (peristalsis) of the intestine, and due to the presence of activated carbon, which has an antimicrobial and sorption effect, it reduces the processes of putrefaction and fermentation that may occur in the intestine.

Allohol is shown in the complex therapy of chronic cholecystitis, with cholangitis, and with symptoms of atonic constipation. It is usually taken in two tablets, after meals, so that it has the most choleretic effect. If the patient is prescribed fractional meals, then the remedy should be taken no more than 4 times. This technique must be observed for a month, and then it is halved in dosage. It is possible to repeat the course, but between them it is necessary to take breaks of at least 2 months.

Allohol is produced by the domestic company Pharmstandard, and a large package containing 50 coated tablets costs only 42 rubles. In some pharmacies, you can find it for 33 rubles, and the smallest pack of 10 tablets costs only 12 rubles.

Advantages and disadvantages

Allochol acts, "choleretic" rather mildly, unlike synthetic drugs. Still, it contains natural bile. But, nevertheless, at a sufficiently high dosage, it can cause diarrhea and flatulence of the abdomen, and Allochol is contraindicated in acute ulcers, mechanical (obstructive) jaundice, and if there are stones in the gallbladder. This leads to a sharp increase in secretion, and if she has nowhere to go, then there may be an expansion of the bladder and even its rupture with the development of peritonitis. Allohol is contraindicated in acute and subacute hepatitis - inflammation of the liver, and with its progressive dystrophy. But this choleretic agent, taken according to indications, acts gently and helps to improve digestion and normalize stools in a wide variety of patient groups.

Odeston belongs to the group of infrequently used synthetic choleretics, and it has a fairly pronounced choleretic effect. This agent contains Hymecromone in the form of an active substance, and is available in the form of tablets weighing 200 mg each.

Odeston reduces the phenomenon of stagnation, reduces the processes leading to the formation of cholesterol stones, that is, it reduces the precipitation of cholesterol in the form of crystals, and is indicated in the treatment of diseases such as biliary dyskinesia of the hyperkinetic type, chronic cholecystitis and cholangitis. It is prescribed after surgery on the gallbladder, and due to a chronic decrease in bile secretion.

Odeston is used half an hour before meals, 1 or 2 tablets, three times a day. The daily dose should not exceed 6 tablets. The course of admission is about 2 weeks. It is not recommended to skip a dose, but you should not make it up later by taking a double dose at once. Odeston is produced by the Polish company Polfa, and you can buy a package of 50 tablets in the fall of 2018 in major cities of the Russian Federation at an average price of 550 rubles.

Advantages and disadvantages

Like all choleretic drugs, Odeston has contraindications. These include obstruction formed in the biliary tract, the phenomenon of renal and hepatic insufficiency, stomach ulcers, bleeding disorders and childhood. The tool has side effects, due to its rather strong choleretic action. This can lead to bloating, diarrhea, allergic reactions, and abdominal pain. Since the remedy is synthetic, many doctors note, along with its strong action, some roughness: Odeston is not intended for mild stimulation.

Perhaps, Holosas is one of the most delicious and pleasant medicines in general, since it is a concentrated syrup of rose hips with sugar. In some cases, if it is not hidden from small children, they can drink the entire bottle, and after that they will suffer from profuse diarrhea due to an overdose, but still, nothing bad will happen to them anymore.

Holosas is indicated for various viral hepatitis, for inflammation of the biliary tract and bladder, for poisoning with various drugs, drugs that are metabolized, secreted into bile, it is indicated for poisoning with alcoholic beverages. Holosas can be prescribed as a general tonic, and with vitamin C avitaminosis.

It should be used 2 to 3 times a day, adults - 1 teaspoon per reception, and children - half a teaspoon, or even less. Holosas is produced by the domestic company CJSC Altayvitaminy, and the cost of one bottle of 140 ml is an average of 86 rubles.

Advantages and disadvantages

Holosas is a natural herbal monopreparation, and only individual intolerance, as well as severe diabetes mellitus, will be a contraindication, since Holosas contains sugar. There are no side effects of the drug, again, with the exception of individual intolerance. Few people will experience unpleasant side effects from the delicious rosehip syrup. This remedy is inexpensive, Holosas can be added to boiling water and drunk for general strengthening purposes. Taking one teaspoon of Holosas fully satisfies the daily need for ascorbic acid.

About hydrocholeretics

Some table medicinal mineral waters are called hydrocholeretics. They simply reduce the density, viscosity of bile, and make it more fluid. Unlike ordinary water, when mineral water is absorbed in the intestinal lumen and enters the portal bloodstream, it is absorbed by the liver cells in the first place, and increases pressure in the bile ducts by osmosis. If it is necessary to increase the secretion of bile, then you need to choose such water as Yessentuki No. 4 (low mineralization) and No. 17 (rich mineralization), Jermuk. It is necessary to consume them 30 minutes before meals, preferably in a warm form and with the released gas, if any.

The best choleretic kinetics: bile diversion stimulants

Cholagogue drugs of this list are divided into two types of opposite action. In the event that the bladder is hypotonic, its smooth muscles are flabby and weak, then it is necessary to increase its tone and increase its ability to contract. At the same time, these agents reduce tonic tension and increase the lumen of the structures of the common bile duct. They simply irritate the intestines by activating the gastrointestinal hormone cascade (cholecystokinin). An example of such a choleretic drug would be magnesium sulfate, or magnesia.

These drugs are prescribed mainly for biliary dyskinesia of the hypotonic type, stagnation in the gallbladder with a decrease in its tone. These remedies are shown for gastritis with low acidity, as well as cholekinetics, which reduce the gallbladder, are shown when performing duodenal sounding in a healthy person.

The second group of drugs includes antispasmodics, which relax an overly contracted gallbladder, reduce its spasm, and along the way relax the bile ducts. This allows you to improve the removal of bile, and an example of such a cholekinetic is No-shpa, Papaverine, or stronger atropine and platifillin, which are used in medical institutions and when calling an ambulance.

These funds are necessary for the hypertensive form of dyskinesia, in the presence of stones in the gallbladder and bile ducts. They are able to reduce the pain syndrome, which often occurs against the background of spasm of the biliary tract and in the presence of cholelithiasis.

Consider the most popular and effective cholekinetics, which are sold in pharmacies and are included in the rating.

Magnesia is the simplest and most affordable choleretic and laxative. This colorless powder, easily soluble in water, has an intense bitter-salty taste, and magnesia is unpleasant to drink. But, in addition to the choleretic effect, it also has an anticonvulsant effect, helps to normalize the heart rhythm, has a hypotensive effect and is able to fight constipation. Magnesia is used for cholecystitis and cholangitis, for obtaining a gallbladder portion of bile during duodenal sounding, for gallbladder dyskinesia of the hypotonic type, for bowel cleansing. Apply magnesium by dissolving one packet (25 g) in one glass of warm water, and drinking between meals 3 times a day, before meals. In this case, already on average, after one or two hours, the drug will have the necessary choleretic effect, which will last for 4 or even 6 hours. Usually, after this, a certain relaxation of the stool occurs, since the osmotically active solution of magnesia will promote an intensive influx of water into the intestinal lumen.

The Moscow Pharmaceutical Factory produces magnesium sulfate, and one 25 g package costs an average of 32 rubles.

Advantages and disadvantages

The advantages of magnesia include its universal availability and low cost, the onset of a quick effect, and a simple and understandable mode of application. But this drug has contraindications. Magnesia should not be taken if the patient has loose stools, symptoms of kidney failure, against the background of low blood pressure and slow heart rate (bradycardia). Magnesia is contraindicated in patients with a variety of cardiac arrhythmias, as it can significantly worsen their condition, especially in the case of complete atrioventricular block, when impulses from the atria are dissociated from ventricular contractions.

Sorbitol, or more precisely, sorbitol, is a polyhydric alcohol, and in addition to choleretic, it has an osmotic and laxative effect. Sorbitol is also used in some cases to reduce the symptoms of intoxication: it removes the toxic substance into the intestinal lumen.

Sorbitol is produced in the form of a powder for oral administration, in sachets, 5 g each, sometimes in powder, packaging of 200, 300, 500 g. constipation tendencies.

It is necessary to use sorbitol for choleretic purposes by dissolving 5 g of the drug in half a glass (100 ml) of slightly warmed water. Take this sweet solution 10 minutes before meals twice a day. The course of treatment is 1 month. Sorbitol is produced by the domestic company Sweet World, and you can purchase the largest package weighing 500 g at an average price of 122 rubles.

Advantages and disadvantages

The advantage of sorbitol is its great cheapness, wide range of applications, since it can be prescribed not only for dyskinesia and cholecystitis, but also for the treatment of constipation. However, sorbitol is contraindicated in all acute conditions, with intolerance to fructose, which is part of it, and if you exceed the required amount, and make the solution either too strong or drink too much of it, intense diarrhea, dry mouth, nausea, and symptoms of dehydration may occur. . But sorbitol can be safely used by diabetics, since it does not contain glucose.

No-shpa (drotaverine)

The most famous antispasmodic tablets No-shpa, or drotaverine hydrochloride, are produced by the Hungarian pharmaceutical company Quinoin. No-shpa is the remedy that allows you to reduce spasms of smooth muscles not only of the gallbladder and bile ducts, but also of the smooth muscles of the urinary tract, so this drug is indicated for renal colic.

No-shpa allows you to reduce the pronounced pain syndrome in the hypertensive form of biliary dyskinesia, with cholangitis, and with cholecystitis. No-shpa is available not only in tablets, but also in solutions, so it is often administered intramuscularly. Only antispasmodics are indicated for pain in the abdominal cavity, in the state of "acute abdomen". The fact is that if you use strong painkillers, you can relieve pain and miss the condition when an urgent operation is required, for example, with acute appendicitis. Antispasmodic drugs do not have an analgesic effect, and all it can do is relax the muscles.

Therefore, if there is a focus of progressive inflammation in the abdominal cavity, for example, with the same calculous cholecystitis, then No-shpa will not help, but if the pain is caused by a spasm in the neck of the gallbladder, then the desired effect will be achieved, the spasm will resolve, bile will come out into the intestines, and the patient's condition will improve.

It is necessary to use No-shpu in tablets from 1 tablet of 40 mg to 6 tablets per day, that is, no more than 2 tablets three times a day, it is advisable to take it before meals so that during meals it shows its effect and relaxes smooth muscle of the bile ducts. One package of No-shpa in the amount of 24 tablets costs about 100 rubles.

Advantages and disadvantages

The big plus of No-shpa is its rather high activity and speed. Quite rarely, overdose symptoms such as arrhythmia occur, but for this the patient must initially have severe heart disease. No-shpa is a universal drug, it not only helps to increase the outflow of bile, but it also helps to normalize the outflow of urine, since the same smooth muscle elements exist in both the ureters and the biliary tract. Few side effects were noted. Of the rare symptoms - tachycardia, headache and nausea, allergic reactions. But, despite all the minor disadvantages, No-shpa is quite in demand, and has long existed in every home first-aid kit as a means of choice for abdominal pain, since only taking antispasmodics will avoid serious complications if surgery is necessary.

Attention! This rating is subjective, is not an advertisement and does not serve as a purchase guide. Before buying, you need to consult with a specialist.

Important! Before taking choleretic drugs, you need to make sure that there are no stones in the gallbladder. This can be done with the help of ultrasound, ultrasound.

Medications for stagnation of bile

To eliminate the stagnation of bile, drugs with different composition and mechanism of action are used. In order to choose the right one, you should consult with your doctor.

There are certain rules for taking almost all choleretic drugs:

• Regardless of the form in which the drugs are released, they are taken before eating no earlier than an hour, washed down with non-carbonated water;
• The daily dose is divided into 2 - 4 doses. It depends on how many times a day the patient eats;
• Eating food after taking such funds is a prerequisite. If the patient remains hungry, he may experience nausea or indigestion;
• Preparations of this group are taken in long courses according to the instructions from 21 to 60 days.
• Then you need a break for 30 - 60 days and, if necessary, you can continue treatment. 2 - 4 courses of admission are allowed per year.

Choleretics

Choleretics are drugs that help the liver increase bile production. They can do this in different ways, depending on the composition:

• True choleretics. They contain bile acids made from extracts of animal or plant origin. As a basis for these drugs, natural bile, intestinal mucosal tissue of animals, their liver or pancreas can be used. In addition to this, extracts of medicinal herbs are used. These drugs include: Allohol, Cholenzim, Liobil, Hologon;

• Synthetic choleretics. They contain compounds obtained by organic synthesis. In addition to the fact that such drugs are choleretic, they have antispasmodic, antibacterial and anti-inflammatory effects. Medicines of this group have a positive effect on digestion, eliminate and suppress fermentation in the intestines. These drugs include: Nicodin, Osalmid, Tsikvalon.
• Medicinal plants that have a choleretic effect. They reduce the viscosity of bile, increase its production and have a positive effect on liver function. These remedies include: Hofitol (artichoke extract), Flamin (immortelle extract), Insadol (corn stigma extract), Febihol (turmeric extract), Berberis-Gommakord (barberry extract), Holosas (rosehip extract). Complex preparations include: Urolesan, Holagol, Travohol.

cholekinetics

Cholekinetics, acting on the gallbladder, increase its tone, at the same time, relaxing the bile ducts. This contributes to the fact that bile is excreted faster. The group of cholekinetics includes drugs such as: Magnesia, Sorbitol, Manit, Xylitol, Flamin, Holosas.

Hydrocholeretics

The action of hydrocholeretics is based on their ability to increase the amount of bile due to the fact that its viscosity decreases. In this case, the amount of water in its composition increases, and it is more quickly excreted into the duodenum.

Such means include mineral waters with alkali: Essentuki, Polyana Kvasova, Borjomi. Also hydrocholeretics are salicylates and drugs based on valerian.

Depending on the pharmacological action, cholespasmolytics include drugs from various groups. But the purpose of their reception is the same - to eliminate spasms of the gallbladder and expand the bile ducts. This helps bile to quickly evacuate into the duodenum. Preparations of this series are taken to relieve pain.

Cholinospasmolytics are divided as follows:

• Synthetic cholenospasmolytics:, Papaverine, Euffilin, Mebeverine;
• Cholinolytics: Platifillin, Bellalgin, Besalol;
• Cholenospasmolytics of plant origin: tinctures of arnica, valerian, elecampane, St. John's wort, lemon balm.

How to get rid of the disease with the help of Allochol

The most popular choleretic agent for stagnation of bile is Allochol. It consists of dry bile, garlic powder, crushed nettle and activated charcoal. A successful combination of components allows for a quick cleansing of the gallbladder. In addition, the medicine helps to improve the functioning of the entire digestive system.

In addition to the fact that Allochol is an effective choleretic agent for stagnation of bile, it also has an affordable price.

Allochol must be taken 1 or 2 tablets at least 3 times a day for a month. In order to get rid of stagnation of bile, it can be used according to the following scheme:
1. 1st day 1 tablet three times;
2. From the 2nd to the 5th - 2 tablets three times;
3. 6th - 3 tablets three times;
4. 7th - 3 tablets three times;
5. From the 8th to the 10th - 2 tablets three times;
6. 11th - 1 tablet three times.

Such cleaning is best done under the supervision of a doctor. If you feel worse, you must stop taking Allohol.

Traditional medicine methods

In addition to drugs that help get rid of the problem, there are folk methods that allow you to quickly and effectively solve the issue of bile stasis. In most cases, the basis of home-made products are medicinal plants.

Choleretic plants include:

• Birch buds;
• Burdock roots;
• Calamus rhizomes;
• Corn silk;
• Artichoke leaves;
• Rowan fruits;
• Wormwood grass;
• Orthosiphon leaves.

On the video Vitaly Ostrovsky - ALL ABOUT THE GALL BLADDER! , Dyskinesia w. P.! THREE HERBS FOR GALE!

Choleretic juices

Effective choleretic agents for stagnation of bile are juices. For the treatment of the disease use:

• Dandelion juice. To prepare the product, a freshly harvested plant is used along with the roots. It is used as a bile secretion stimulant. It also helps to effectively remove bile. With stagnation of bile, take 20 ml of fresh juice 2 times a day. It will take 30 days to get rid of the disease;
• Rowan juice. In order to prepare juice, ripe fruits are used, collected after the first frost. It is an effective diuretic. It is used 20 ml 3 times a day. Treatment must be continued for 21 days;

• Turnip juice garden. The intake of juice from this root vegetable stimulates the contractile function of the bile ducts and is indicated for narrowing of the bile ducts. It is taken 25 ml up to 3 times a day. Treatment should be continued until the patient's condition improves. It is not recommended to use turnip juice for peptic ulcer;
• Radish juice. It enhances the formation of bile and quickly removes it from the gallbladder to the intestines, and improves the functioning of the stomach with low acidity. Take this medicine 25 ml up to 3 times a day. You should not get carried away with such treatment with, and with high acidity;
• Pear juice. Used to improve bile production. It must be consumed 100 ml in the morning and evening. The period of application is not limited.

How to prepare juices for treatment

In order to preserve all the beneficial substances, medicinal juices should be prepared immediately before use. Raw materials must be thoroughly washed, dried with a paper towel. Juice can be squeezed using a juicer, or, after grinding the raw materials in a meat grinder, squeeze through gauze.

In the event that it is not possible to prepare fresh juice or it is necessary to store it for a certain period, 70% medical alcohol can be used as a preservative, which is added in a ratio of 1:5. The finished product should be stored in a cool place.

Decoctions that increase bile production

In the event that bile is produced in insufficient quantities, the following folk methods are used:

• St. John's wort, celandine, knotweed, dandelion root and anise fruits are mixed, 2 parts of corn stigmas are added. Half a liter of water is poured into 5 g of the collection and boiled over low heat for 5 minutes. After the broth has cooled, it is filtered. For a day, you need to drink 300 ml of the drug, divided into 3 doses;
• A mixture is prepared from 2 parts of immortelle flowers and St. John's wort. A liter of water should be poured with 15 g of the collection and left for 10 hours. Then the product is put on fire and boiled for 7 minutes. Use it in 100 ml one hour after eating. It is necessary to drink 400 ml of broth per day. Continue treatment for 21 days. If there is a need to continue treatment, then the break should be at least a week. Ready broth to store in a cold place;

• Mix 1 part each of corn stigmas, nettle, milk thistle seeds and knotweed herb. 400 ml of cold water is poured into 5 g of dry raw materials and allowed to brew for at least 6 hours. Then the decoction is boiled for 5 minutes. Cool it in a sealed container and strain. Take 300 - 400 ml per day, divided into several doses. Treatment continues for fourteen days.

Infusions for spasms of the gallbladder

If bile stasis occurs due to spasms of the gallbladder, then in this case, decoctions and infusions prepared from the following medicinal preparations are used:

• Mix in the same proportion the grass of celandine, peppermint leaves and cinquefoil. Pour 250 ml of boiling water over 2 g of the collection and allow to cool slightly. The infusion should be used hot, twice a day for 2 weeks;
• Prepare a mixture of 2 tablespoons of valerian root, mint leaves and St. John's wort. Add 1 tablespoon herb wormwood and hop cones. Pour 3 g of the collection with three hundred milliliters of boiling water and leave for a quarter of an hour. Strain and take orally 100 ml three times a day;
• Mix hop cones, nettle leaves, immortelle and wormwood herb. 2 g of the collection is poured into 200 ml of boiling water and placed in a thermos. Let it brew for at least 2 hours. Filter and take 50 ml before each meal.
• In the same proportion, corn stigmas are mixed with sandy immortelle flowers. 3 g of dry raw materials are poured into 300 ml of boiling water and allowed to brew for 2 hours. The resulting infusion should be drunk during the day, divided into three doses.

Decoctions for impaired function of the gallbladder and ducts

With stagnation of bile as a result of dysfunction of the gallbladder or bile ducts, the following remedies are used:

• A mixture is prepared from coriander fruits, 2 parts of mint leaves, 3 parts of three-leaf watch leaves and 4 parts of sandy immortelle. For 200 ml of boiling water, add 2 g of the mixture and boil for 10 minutes. After cooling the broth, it should be filtered. Take 40 minutes before meals in the morning and evening. At a time you need to drink 100 ml.
• Mix gentian root, fennel fruit and three-leaf leaves 1 part each, add dandelion root, barberry leaves and mint 2 parts each. Boil 3 g of the collection in 300 ml of water for 7 minutes. Let it brew for 40 minutes. After this, strain the infusion and take 3 tablespoons three times a day before eating;

A choleretic agent for stagnation of bile is an infusion of sandy immortelle. To prepare this folk remedy, 10 g of flowers are poured into 200 ml of water and insisted under the lid for an hour. Take half an hour before meals according to the following scheme:
1. On the 1st day 1 time 70 ml;
2. In the 2nd - 2 times 70 ml;
3. On the 3rd - 3 times 70 ml;
4. On the 4th - 3 times 100 ml;
5. On the 5th - 2 times 100 ml;
6. On the 6th - 1 time 100 ml.

If necessary, after a week break, the course is repeated.

Tyubazh

Tubage is a washing of the gallbladder and bile ducts. Three days before the procedure, you must refuse fatty and fried foods. Preference should be given to vegetable food, steamed or boiled.

The procedure is carried out in the morning. To do this, take one of the following solutions:

• 500 ml of non-carbonated mineral water (Essentuki, Borjomi). Its temperature should be about 40 degrees;
• 250 ml hot water to which 1 tablespoon of sulfate powder is added;
• 200 ml of water, in which a tablespoon of Sorbitol is dissolved;
• 2 tablespoons of Holosas and a glass of mineral water.

After that, they lie on their right side, applying a warm heating pad to the hypochondrium. It is necessary to lie down for 2 hours, during this period the gallbladder is cleared. The procedure is considered effective if, after this time, bowel movement occurs. In this case, small colic may occur.

Important! Such a procedure can be carried out only as prescribed by a doctor, no more than once every six months.

Oils

With stagnation of bile, vegetable oils of the first pressing are the most effective: olive, sunflower, linseed. They must be consumed daily, on an empty stomach in a tablespoon or dessert spoon, and after half an hour start breakfast. In this case, they will help not only get rid of stagnation of bile, but also improve digestion.

As a strong choleretic agent for stagnation of bile, you can use self-prepared flax oil, which contains a large amount of nutrients and vitamins. To prepare it, 100 g of flax seeds are crushed with a coffee grinder and placed in an 850 g jar, then it is filled to the top with refined olive or sunflower oil. The remedy must be infused for a week in a dark place.

You need to take this oil in a tablespoon, daily in the morning on an empty stomach. Continue treatment until the symptoms of the disease are relieved. If side effects appear in the form of, or abdominal pain, the amount of oil must be reduced.

An effective remedy that allows you to quickly get rid of the disease is natural ground coffee. Every day in the morning you need to drink a cup of this drink without sugar and eat a small piece (on the tip of a knife) of butter.

Milk thistle for treatment

Milk thistle is one of the most famous and effective choleretic agents that are used in both folk and traditional medicine. In order to successfully cope with the disease, you can use meal, which is easy to purchase at any pharmacy. It is a powder that remains after pressing the oil. It will take 400 g for the course of treatment. It is taken daily three times a day for half an hour before meals. A teaspoon of the powder is swallowed and washed down with water.

To make your own meal, milk thistle seeds are ground with a coffee grinder just before ingestion and ingested before each meal.

In order to prepare milk thistle oil, the seeds are crushed, placed in a glass container and poured with extra virgin olive oil. Let it brew for a week in a dark place and take a dessert spoon once a day before meals.

In order to prepare a choleretic decoction, a tablespoon of the seed is poured into 250 ml of water and boiled over low heat for 5 minutes. After that, let it brew for an hour, filter and consume 100 ml 2 times a day before meals.

Treatment of bile stasis in childhood

Gallbladder problems can occur not only in adults, but also in children. In order to get rid of cholestasis, various choleretic agents are used. The safest choleretic agents for cholestasis, bile stasis for children:

• Allochol;
• Nicodin;
• Flamin;
• Febihol;
• Holosas;
• Hofitol;
• Valerian;
• sulfate.

A safe remedy for the treatment of children with cholestasis.

The dosage of all these choleretic drugs for children should be calculated by the doctor, according to the instructions, based on the weight and age of the child. It is also necessary to introduce natural juices and alkaline mineral waters into the child's diet.

Important! Infusions and decoctions of choleretic herbs, as well as alternative methods for the treatment of children with cholestasis, whose age is less than 12 years, should be used with caution and only under the supervision of a physician, since they can cause unwanted side reactions.

Contraindications

Despite the benefits of taking choleretic drugs for cholestasis, it must be remembered that there are contraindications for their use:

1. The presence of large stones in the gallbladder or bile ducts. When taking choleretic drugs, they can budge, clog the bile ducts and cause hepatic colic. They can also cause an inflammatory process. In such cases, surgical intervention is indicated;
2. Peptic ulcer in the acute stage;
3. Individual intolerance to the components of the drug;
4. Spicy .

The most effective means

When people get cholestasis, they ask themselves: what is the best, most effective remedy for bile stasis? There is no single answer in this case. Allohol is suitable for some people, teas based on medicinal herbs are suitable for others. It depends on the individual characteristics of the body, and therefore it is necessary to contact specialists, gastroenterologists, for a personal consultation or appointment.

It is possible to verify the effectiveness of one or another choleretic agent for cholestasis only after the full course of treatment with the chosen drug or method has been completed.

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Currently choleretic drugs in the complex treatment and prevention of various diseases of the liver and gallbladder are widely used in the clinical practice of a gastroenterologist. This is due to the effects of choleretic drugs that relieve pain attacks, alleviate the course of the disease, and also prevent the deterioration or the appearance of a new pathology provoked by decompensation of an existing disorder.

To understand why choleretic drugs are needed, you should know what bile is, what its physiological functions are, and how it moves in the digestive system. Bile is a biological fluid produced by liver cells and stored in the gallbladder. The liquid has a bitter taste, a specific odor and, depending on the prescription of production, can be colored yellow, brown or greenish. Bile performs the following physiological functions in the human body:

• Emulsification and digestion of dietary fats;
• Activation of enzymes of the small intestine and pancreas, necessary for the complete digestion of food;
• Provides complete absorption of fat - soluble vitamins , calcium and cholesterol .

Activation of the enzymes of the small intestine and pancreas is due to the fact that bile neutralizes the effect of pepsin, which came in place with the food bolus from the stomach. After neutralization of pepsin, the necessary conditions are created for the functioning of the enzymes of the small intestine and pancreas.

Emulsification of fats is carried out by bile acids contained in bile, which also improve intestinal motility, stimulate the formation of protective mucus and prevent the attachment of bacteria and proteins to the mucous membrane. Due to these effects, bile prevents constipation and intestinal infections. In addition, bile is necessary for the excretion of substances such as cholesterol, bilirubin, glutathione and steroid hormones from the human body along with feces.

Bile is synthesized by the liver cells and enters the gallbladder through special ducts. Then from the gallbladder, also through the duct system, it enters the duodenum, where it performs its physiological functions. That is, the gallbladder is a kind of reservoir for the temporary storage of bile from the moment it is produced until the food bolus enters the duodenum.

Classification of choleretic drugs

Currently, an anatomical-therapeutic-chemical classification of choleretic agents is used, which takes into account both the chemical structure of the drug used, its therapeutic effects, and the anatomical structures affected by the drug. Such an integrated approach makes it possible to create the most complete classification that reflects various aspects of the use, therapeutic effects and absorption, distribution and excretion of drugs from the human body.

So, today choleretic drugs are classified into the following groups and subgroups:

1. Choleretics(drugs that increase the production of bile by liver cells):

True choleretics that increase the production of bile due to the active synthesis of bile acids:

• Choleretics containing bile acids and made on the basis of plant or animal raw materials (for example, animal bile, plant extracts, etc.);
• Synthetic choleretics, which are chemicals obtained by organic synthesis and have the property of increasing bile production;
• Medicinal herbs with a choleretic effect (used in the form of infusions, decoctions, etc.).

Hydrocholeretics, which are substances that increase the volume of bile by diluting it light and increasing the percentage of water in it.

2. cholekinetics(means that improve the outflow of bile by increasing the tone of the gallbladder and simultaneously relaxing the bile ducts).

3. Cholespasmolytics (means that improve the outflow of bile by relaxing the muscles of the gallbladder and biliary tract):

• anticholinergics;
• Synthetic antispasmodics;
• Antispasmodics made on the basis of vegetable raw materials.

4. Drugs to reduce the bile lithogenicity index (remedies prevent the formation of stones in the gallbladder and contribute to the dissolution of existing ones):

• Preparations containing bile acids - ursodeoxycholic or chenodeoxycholic;
• Preparations containing highly active solvents of organic compounds of a lipid nature, for example, methyl tert-butyl ether.

True choleretics, containing bile acids as active components, are drugs, mainly made on the basis of animal raw materials. Most often, natural bile, extracts of the liver or pancreas, as well as tissues of the mucous membrane of the small intestine of healthy animals are used as raw materials. That is why choleretic drugs of this group are often called means of animal origin. In addition to animal raw materials, many complex preparations may include extracts of medicinal herbs that have the necessary choleretic effect.

Synthetic choleretics are preparations that contain as active substances only compounds obtained in the course of organic synthesis. The drugs of this group, in addition to the choleretic action, also have the following therapeutic effects: antispasmodic (reduce pain in diseases of the biliary tract and gallbladder), hypolipidemic (reduce the concentration of cholesterol in the blood), antibacterial (destroy pathogenic bacteria that provoke inflammatory diseases of the biliary tract) and anti-inflammatory (stop inflammation present in the biliary tract). In addition, synthetic choleretics suppress the processes of putrefaction and fermentation in the intestines, thereby eliminating bloating, stool instability and other dyspeptic phenomena.

Medicinal herbs with choleretic action improve liver function, increase bile secretion, while reducing its viscosity. Herbs also increase the concentration of cholates in bile. Along with the choleretic effect, medicinal herbs also have a cholekinetic effect, that is, on the one hand, they increase the secretion of bile, and on the other, they improve its excretion, due to which a complex therapeutic effect on the human body is achieved. Herbal preparations are also able to have anti-inflammatory, antimicrobial and diuretic effects. Due to the content of only various herbs as active substances, preparations of this group are often called herbal choleretic agents.

Hydrocholeretics increase the volume of bile due to its dilution and decrease in viscosity, achieved by increasing the content of the water fraction in it. In such a situation, the excretion of bile is facilitated and the formation of stones is prevented.

cholekinetics are means that increase the tone of the gallbladder and at the same time relax the muscles of the bile duct. To understand the significance of the effect of cholekinetics, it is necessary to know that the gallbladder is connected to the duodenum by the bile duct, through which bile flows from one organ to another. Accordingly, with an increased tone of the bile duct, it narrows, which interferes with the progress of bile. And with a low tone of the gallbladder, it simply does not "push" bile into the duct. Thus, an increase in the tone of the gallbladder and relaxation of the duct create ideal conditions for the outflow of bile, since the first is intensively reduced, pushing the contents out of itself and not allowing it to stagnate, and the second has a wide enough lumen to skip the entire volume within a short period of time. The resulting effect of cholekinetics is the release of the gallbladder and the flow of bile into the duodenum, resulting in improved digestion and elimination of stagnation.

Cholespasmolytics are divided into several groups depending on the characteristics of their pharmacological action, but the resulting effects are the same for everyone. Cholespasmolytics eliminate spasm and expand the biliary tract, facilitating the excretion of bile into the intestine. These drugs are usually used in short courses to relieve pain in various diseases of the gallbladder and biliary tract.

Drugs to reduce the lithogenicity of bile, strictly speaking, are designed to dissolve existing gallstones and prevent the formation of new ones. Since these drugs have a choleretic effect, they are classified with a certain degree of convention as a choleretic group.

Each group and subgroup includes certain drugs that have a number of properties and clinical effects used in various pathologies of the biliary tract and liver. In the next section, we give a list of choleretic drugs belonging to each group and subgroup.

Cholagogue drugs - lists

Below, for ease of orientation and selection, we present a list of choleretic drugs by classification groups. At the same time, we will first indicate the international name of the active substance, and next to or in brackets a number of commercial names under which the drug can be produced.

True choleretics

True choleretics containing bile components include the following drugs:

• Preparations containing components of the natural bile of animals - Allohol, Cholenzim, Vigeratin, Liobil;
• Dehydrocholic acid - Hologon;
• Sodium salt of dehydrocholic acid - Decholin, Biliton, Supracol, Holamine, Holomin.

Synthetic choleretics

Synthetic choleretics are the following drugs:

• Hydroxymethylnicotinamide (Nicodin, Bilamid, Bilizarin, Bilocid, Cholamid, Coloton, Felosan, Isochol, Niciform);
• Hymecromon (Odeston, Holonerton, Holestil);
• Osalmid (Oxafenamide, Osalmid, Auxobil, Drenamid, Driol, Enidran, Salmidochol);
• Cyclovalone (Cyclovalone, Benevo, Cyclovalone, Divanil, Divanone, Flavugal, Vanilone).

Herbal choleretics

Herbal choleretics are as follows:

• Immortelle flower extract (Flamin);
• Extract of corn stigmas (Peridol, Insadol);
• Tansy extract (Tanacehol, Tanaflon, Sibektan, Solaren);
• Turmeric extract (Konvaflavin, Febihol);
• Sumpia leaf extract (Flacumin);
• Barberry leaf and root extract (Berberine sulfate, Berberis-Homaccord, Berberis plus);
• Rose hip extract (Holosas, Holemaks, Holos);
• Hemp datiski extract (Datiscan);
• Volodushka extract (Pekvokrin);
• Artichoke extract (Hofitol, Holebil);
• Preparations containing a complex of herbs with a choleretic effect (Cholagol, Cholagogum, Travohol, choleretic preparations No. 2 and 3, Urolesan, Phytohepatol No. 2 and 3).

Hydrocholeretics

Hydrocholeretics are the following drugs:

• Alkaline mineral waters (Naftusya, Borjomi, Narzan, Essentuki 17, Essentuki 4, Arzni, Smirnovskaya, Slavyanovskaya, Izhevskaya, Jermuk, etc.);
• Salicylates (sodium salicylate);
• Valerian preparations (alcoholic infusion of valerian, valerian tablets, Valerianahel, etc.).

cholekinetics

Cholekinetics are the following drugs:

• Magnesium sulfate (Magnesia, Cormagnesin);
• Sorbitol (Sorbitol);
• Mannitol (Mannitol, Mannitol);
• Xylitol;
• Barberry leaf and root extract (Berberine sulfate, Berberis-Homaccord, Berberis plus);
• Immortelle flower extract (Flamin);
• Rosehip fruit extract (Holosas, Holemaks, Holos).

Cholespasmolytics

Cholespasmolytics are the following choleretic drugs:
1. Anticholinergics:

• Bellalgin;
• Belloid;
• Besalol;
• Metacin;
• Platifillin;
• Spasmolitin;
• Fubromegan.

2. Synthetic cholespasmolytics:

• Papaverine (Papaverine, Papaverine Bufus, Papazol);
• Drotaverin (Bioshpa, Nora-Drotaverin, Droverin, No-Shpa, Nosh-Bra, Ple-Spa, Spazmol, Spazmonet, Spazoverin, Spakovin);
• Aminophylline (Aminophyllin-Eskom, Eufillin);
• Mebeverin (Duspatalin).

3. Herbal cholespasmolytics:

• Arnica tincture;
• Valerian tincture;
• Elecampane tincture;
• Hypericum tincture;
• Mint tincture;
• Melissa tincture;
• Tincture of calendula flowers;
• Convaflavin (turmeric root);
• Cholagol (extracts of various herbs).

Choleretic with litholytic action

Choleretic with litholytic action are as follows:
1. Ursodeoxycholic or chenodeoxycholic acids - Livodex, Urdox, Urso 100, Ursodez, Ursodex, Uroliv, Ursolit, Ursor C, Ursosan, Ursofalk, Choludexan, Exhol;
2. Methyl tert-butyl ether.

Choleretic herbal preparations

Choleretic herbal preparations are presented in finished dosage forms (tablets, tinctures or powders for oral solution) or dried crushed parts of plants with the necessary properties.

Currently, the domestic pharmaceutical market has the following choleretic herbal preparations in finished forms:

• Berberis-Homaccord;
• Berberis plus;
• Berberine sulfate;
• Datiscan;
• Insadol;
• Peridol;
• Convaflavin;
• Pekvokrin;
• Sibektan;
• Solaren;
• Tanaflon;
• Tanacehol;
• Travohol;
• Urolesan;
• Febihol;
• Phytogepatol No. 2 and 3;
• Flacumin;
• Flamin;
• Holagogum;
• Cholagol;
• Holebil;
• Cholemax;
• Holos;
• Holosas;
• Hofitol.

In addition, the following medicinal herbs have a choleretic effect (choleretic):

• Birch buds;
• Turmeric root;
• Calamus rhizome;
• Roots and leaves of barberry;
• Burdock roots;
• Dandelion roots;
• chicory root;
• Corn silk;
• Artichoke leaves;
• Volodya leaves;
• nettle leaves;
• Peppermint leaves and oil;
• Orthosiphon leaves;
• parsley leaves;
• Skumpia leaves;
• Leaves and flowers of tansy;
• fir oil;
• Terpene oil Rose hips;
• coriander fruit;
• Rowan fruits;
• Carrot seeds;
• Horseradish root juice;
• Grass mountaineer bird;
• Danish grass;
• Herb oregano;
• Herb centaury;
• Lily of the valley grass;
• Artemisia grass;
• Immortelle flowers;
• Cornflower flowers;
• Tatar flowers.

The following products and medicinal herbs have a cholekinetic effect:

• Calamus rhizomes;
• Dandelion roots;
• Rhubarb roots;
• leaves of barberry;
• Cowberry leaves;
• Watch leaves;
• Coriander oil;
• Juniper oil;
• Cumin oil;
• Olive oil;
• Coriander fruits;
• Juniper fruits;
• Cumin fruits;
• fennel fruit;
• Dog-rose fruit;
• Sunflower oil;
• Cowberry juice;
• Grass mountaineer bird;
• Herb oregano;
• Shepherd's purse grass;
• thyme herb;
• Yarrow herb;
• Immortelle flowers;
• Cornflower flowers;
• Marigold flowers;
• Chamomile flowers.

Modern choleretic drugs

Modern choleretic drugs are represented by a group of synthetic choleretics and combined herbal and animal remedies. Synthetic choleretics include preparations containing nikodin, hymecromone, osalmid or tsikvalon as active substances. Synthetic choleretics compared to natural ones (for example, Allochol, Holenzim, Liobil, etc.) are better tolerated, do not cause unstable stools, and also have a number of additional positive therapeutic effects, such as antispasmodic, lipid-lowering, antibacterial and anti-inflammatory.

In addition, modern choleretic drugs include dehydrocholic acid (Hologon, Decholin) and ursodeoxycholic acid (Livodex, Urdox, Urso 100, Ursodez, Ursodex, Uroliv, Ursor, Ursor C, Ursosan, Ursofalk, Choludexan, Exhol). Also a modern drug is the cholespasmolytic Duspatalin.

Among the choleretic herbal and animal preparations, the following are modern:

• Berberis-Homaccord;
• Vigeratin;
• Insadol;
• Convaflavin;
• Pekvokrin;
• Peridol;
• Sibektan;
• Solaren;
• Tanacehol;
• Tanaflon;
• Urolesan N;
• Febihol;
• Holagogum;
• Cholagol;
• Holaflux;
• Holosas.

Choleretic drugs - indications for use

A common indication for the use of choleretic drugs is the pathology of the gallbladder, biliary tract or liver. However, in order to select the optimal drug, it is necessary to know the indications for the use of each group of choleretic agents. Within the groups, there are slight differences between the drugs, which, however, do not affect their indications for use, which remain the same. Thus, for clinical orientation in choleretic preparations, it is necessary to know the indications for the use of each classification group, which we will consider below.

Choleretics

Indications for the use of choleretics are the same for all three subgroups of this group of choleretic agents. This means that both synthetic choleretics (for example, Tsikvalon, Nicodin, Oxafenamide, etc.), and preparations containing natural bile components (for example, Allochol, Liobil, Decholin, Cholenzim, Hologon, etc.), and herbal remedies (for example, Convaflavin, Holosas, Flacumin, etc.) have the same indications for use. So, choleretics are indicated for use in the following conditions or diseases:

• Chronic inflammatory diseases of the liver (for example, hepatitis, steatosis, etc.);
• Chronic inflammatory diseases of the biliary tract (cholangitis, cholecystitis, etc.);
• Habitual constipation, provoked by a violation of the outflow of bile.

Choleretics, depending on the characteristics of the course, diseases can be used in combination with antibiotics, painkillers, antispasmodics and laxatives.

In addition, with insufficient bile secretion, choleretics containing components of natural bile of animals can be used as replacement therapy drugs.

Among choleretics, the most "hard" are drugs containing bile components, so they are the worst tolerated and often provoke stool disorders. Synthetic choleretics have a milder effect, but in terms of the spectrum of positive therapeutic effects, they are significantly inferior to drugs containing bile components. In addition, synthetic choleretics do not improve the properties of bile, as natural preparations and products containing medicinal herbs. But synthetic choleretics, in addition to choleretic properties, have the following therapeutic effects:

• Antispasmodic effect (eliminate spasm and pain in the biliary tract) is expressed in osalmid and gimecromon;
• Lipid-lowering effect (reduce the concentration of cholesterol in the blood due to its excretion from the body) is expressed in osalmid;
• Antibacterial effect expressed in Nicodin;
• Anti-inflammatory effect expressed in tsikvalon;
• Suppression of decay and fermentation in the intestines - the effect is pronounced in nicodine.

These therapeutic effects must be taken into account when choosing the optimal drug. For example, if a person has a pronounced pain component, then he needs a choleretic drug with an antispasmodic effect. That is, he needs to choose a drug containing osalmid or gimecromon. If diseases of the biliary tract and gallbladder are combined with atherosclerosis, hypertension and high blood cholesterol, then a drug containing osalmid should be chosen. With pronounced inflammatory changes in the wall of the gallbladder or biliary tract, it is necessary to choose drugs with tsikvalon.

Herbal choleretics have a milder effect compared to synthetic and natural preparations containing bile components. In addition, they have a complex positive effect on the organs of the gallbladder, ducts and liver, due to which their very high efficiency is achieved. That is why at present, in the absence of allergies or intolerance to herbal components, it is recommended to use preparations containing herbal components as choleretics.

Hydrocholeretics

Indications for the use of hydrocholeretics, in principle, do not differ from those for choleretics. However, drugs in this group are almost never used on their own. They are usually used in combination with other choleretic agents, mainly choleretics and cholekinetics, to enhance the therapeutic effect.

cholekinetics

Indications for the use of cholekinetics are as follows:

• Biliary dyskinesia of hypotonic form;
• Atony of the gallbladder with stagnation of bile, combined with dyskinesia;
• Chronic cholecystitis;
• chronic hepatitis;
• Gastritis with low or zero acidity (hypoacid or anacid) of gastric juice;
• Preparation for duodenal sounding.

Cholekinetics cause an increase in the tone of the gallbladder and relaxation of the sphincter of Oddi, so they are prescribed mainly for the hypotonic form of biliary dyskinesia. Indications for their use are atony of the gallbladder with bile stasis in dyskinesia, chronic cholecystitis, chronic hepatitis, in anacid and severe hypoacid conditions. They are also used during duodenal sounding.

Cholespasmolytics

Indications for the use of cholespasmolytics are as follows:

• Biliary dyskinesia of hyperkinetic form;
• Moderate pain syndrome accompanying diseases of the biliary tract and gallbladder.

Basically, cholespasmolytics are used to relieve moderate pain on an outpatient basis or at home.

Indications for the use of choleretic drugs with litholytic action

Indications for the use of choleretic drugs with litholytic action are as follows:

• Dissolution of small stones in the gallbladder and prevention of the formation of new ones;
• Dissolution of fragments of stones formed after the procedure of ultrasonic crushing;
• Complex treatment of cholelithiasis;
• Reflux gastritis or reflux esophagitis, provoked by the reflux of bile acids into the stomach or esophagus;
• Acute hepatitis;
• Toxic damage to the liver by poisons, alcohol, drugs, etc.;
• Compensated biliary cirrhosis of the liver;
• Primary cholangitis;
• Atresia of the intrahepatic biliary tract;
• Stagnation of bile on the background of parenteral nutrition;
• Biliary dyskinesia;
• Complex treatment of chronic opisthorchiasis;
• Prevention of liver damage against the background of the use of cytostatics or oral contraceptives.

Taking choleretic drugs - a brief instruction

All choleretic drugs, regardless of the form of release, must be taken 20 to 30 minutes before meals. Moreover, the total daily dosage is divided equally into 3-5 doses, depending on how many times a day a person eats. It is recommended to take choleretic drugs before each meal. The preparations must be washed down with a sufficient amount of water and be sure to eat something half an hour after taking. If a person does not eat something after taking a choleretic drug, then he will experience nausea, diarrhea and general well-being will worsen.

Usually, choleretic drugs are taken in long-term (up to 3-8 weeks) courses 2-4 times a year, with intervals of at least 1-2 months between them. Such courses of use of choleretic drugs are prophylactic and should be carried out during the entire period of time while the disease persists. With exacerbation of diseases of the biliary tract, liver and gallbladder, choleretic drugs are used as part of complex therapy in large dosages.

Ursodeoxycholic acid preparations for the treatment of reflux gastritis and reflux esophagitis, as well as the dissolution of gallstones, must be taken continuously for 6 to 8 months.

Cholagogue preparations for children

In children, the following choleretic drugs can be used:

• Choleretics containing components of natural bile - Allochol;
• Synthetic choleretics - Nicodin, Oxafenamide, Osalmid;
• Choleretics containing medicinal herbs - Flamin, Febihol, Holosas, Cholemax, Holos, Hofitol;
• Cholekinetics - Valerian, Valerianahel, Magnesia, Cormagnesin, magnesium sulfate;
• Cholinolytics (cholespasmolytics) - Atropine, Metacin, Platifillin, Papaverin, Papazol, Drotaverin, No-Shpa, Bioshpa, Nora-Drotaverin, Nosh-Bra, Ple-Spa, Spazmol, Spazmonet, Spazoverin, Spakovin Eufillin.

The dosage of the above choleretic drugs is calculated individually by body weight, based on the ratio indicated in the instructions for each specific drug.

In addition, children can drink alkaline mineral waters (Borjomi, Essentuki 17, Essentuki 4, Jermuk, Slavyanovskaya, etc.) as natural hydrocholeretics. Medicinal herbs with a choleretic effect in children under 12 years of age are recommended not to be used, since prepared infusions and decoctions contain a wide range of active substances and it is simply impossible to predict the reaction of a child's body to all of them.

Cholagogue drugs during pregnancy

Pregnant women can take only those choleretic drugs that do not provoke contractile activity of the uterus and do not penetrate the placenta to the fetus, and also do not cause a pronounced deterioration in the condition. The following choleretic drugs are absolutely safe during pregnancy:

• Holenzim;
• Holosas;
• Cholemax;
• Holos;
• Valerian;
• Magnesia (magnesium sulfate);
• Cormagnesin;
• Atropine;
• Metacin;
• Papaverine (Papazol);
• Drotaverin (No-Shpa, Bioshpa, Nora-Drotaverin, Nosh-Bra, Ple-Spa, Spazmol, Spazmonet, Spazoverin, Spakovin).

In addition, there is a group of choleretic drugs that can be taken during pregnancy under the supervision of a doctor and only as directed. These drugs are theoretically safe for pregnant women, but experimental clinical studies have not been conducted for obvious ethical reasons. Therefore, the instructions usually write that the drugs can be used during pregnancy, but only under the supervision of a doctor. These choleretics include the following:

• Odeston;
• Holonerton;
• Cholestil;
• Flamin;
• Febihol;
• Berberis-Gommakord;
• Hofitol;
• Eufillin.

It is better not to use medicinal herbs with a choleretic effect during pregnancy, since their infusions and decoctions contain a large number of active substances, the effects of each of which cannot be assessed in advance and with high accuracy. If necessary, you can choose ready-made dosage forms based on herbs, for example, Holosas, Cholemax, Cholenzim, etc.

Dosages, rules of administration and duration of therapy with choleretic drugs in pregnant women are exactly the same as usual.

The use of choleretic drugs for certain diseases

Biliary dyskinesia (BDB)

The choice of drugs depends on the form of biliary dyskinesia. Yes, at hypertensive type of biliary dyskinesia (ZHVP) shows the following choleretic drugs:

• Cholespasmolytics of any type (for example, No-Shpa, Papaverine, Platifillin, Metacin, Duspatalin, Odeston, etc.), which reduce pain;
• Cholekinetics (for example, Magnesia, Cormagnesin, Berberine-Gommakord, Holosas, Cholemax, Holos, Sorbitol, Mannitol, Flamin, etc.).

The general scheme of therapy is usually as follows - cholespasmolytics are used in short courses to eliminate pain, after which a long-term intake of cholekinetics begins. Cholespasmolytics can also be used episodically as needed. With a hypertensive type of dyskinesia of the biliary tract, choleretic drugs from the group of choleretics and hydrocholeretics, for example, Allochol, mineral waters, etc., cannot be used.

With dyskinesia of the biliary tract by hypotonic type the following choleretic drugs are indicated:

• Any choleretics (for example, Allohol, Liobil, Nicodin, Tsikvalon, Cholagogum, Cholagol, Flacumin, Konvaflavin, Febihol, Sibektan, Tanacehol, etc.);
• Hydrocholeretics (alkaline mineral waters, etc.);
• Antispasmodics of myotropic action (Duspatalin, Odeston).

Choleretics are used in long courses of 4 to 10 weeks, and antispasmodics in short cycles of 7 to 14 days. Alkaline mineral waters can be drunk constantly. Cholekinetics in the hypotonic form of biliary dyskinesia are usually not used.

Cholagogue preparations for stagnation of bile

In this case, to eliminate congestion, the most effective and optimal are their choleretic groups of cholekinetics, for example, Kormagnesin, Berberine-Gommakord, Holosas, Mannitol, Flamin, etc.

Cholecystitis

Choleretic drugs for cholecystitis are used at any stage of the disease. In the presence of stones in the gallbladder with cholecystitis, only products containing ursodeoxycholic acid as an active substance can be used as choleretic drugs (for example, Livodex, Urdox, Urso 100, Ursodex, Ursodex, Uroliv, Ursolit, Ursor C, Ursosan, Ursofalk, Choludexan , Exhol).

With non-stone cholecystitis, it is necessary to take choleretics from any group. Among synthetic choleretics, choleretic ones containing oxafenamide and hymecromone or cyclovalone as active substances are optimal. When using oxafenamide or hymecromon, it is not necessary to additionally take cholespasmolytics (No-Shpa, Papaverine, etc.), since these synthetic choleretics have an antispasmodic effect. And against the background of the use of cyclovalon, you do not need to additionally take antibacterial drugs, since this choleretic has a pronounced antimicrobial effect. When using choleretics containing bile components or medicinal herbs (for example, Allochol, Liobil, Sibektan, Tanacehol, etc.), it is necessary to additionally take cholespasmolytics or antibacterial drugs.

In addition to any choleretics for non-stone cholecystitis, it is necessary to take cholekinetics (Magnesia, Cormagnesin, Berberine-Gommacord, Holosas, Cholemax, Holos, Sorbitol, Mannitol, Flamin, etc.), which will facilitate the release of bile into the duodenum from the gallbladder.

There are very few negative reviews about choleretic drugs and they are usually due to the ineffectiveness of a particular drug in this particular case. The lack of a clinical effect causes disappointment in a person, from which he concludes that the drug is ineffective, and leaves a negative review about it.

However, choleretic drugs are very effective if taken correctly and as directed, taking into account the properties of each drug. Therefore, a negative review of any drug is not a reflection of its inefficiency, but of the wrong choice of medicine.

Cholagogue drugs - prices

Prices for choleretic drugs are very variable and range from 50 to 500 rubles per pack. The cost of the drug depends on the manufacturer (imported drugs are more expensive than domestic ones) and its composition. The cheapest are preparations containing components of natural bile and medicinal herbs. The most expensive are synthetic choleretics, cholespasmolytics and ursodeoxycholic acid preparations. That is, there are groups of drugs with a relatively expensive and cheap cost. However, since in each case choleretic drugs from a certain group are shown, it is impossible to replace them with drugs from another, cheaper classification subgroup. You can only choose the cheapest drug from the same group. This principle of substitution should always be used when choosing a choleretic drug.

Cooking choleretic salad Marco Polo - video

Before use, you should consult with a specialist.

Bile is a biological fluid that is formed as a result of the process of the liver cells. Like all other biological processes in the human body, the outflow of the secretion of the gallbladder must be constantly carried out during meals, otherwise serious health problems may arise. If there is stagnation, then after the examination, specialists prescribe choleretic drugs to patients.

The role of bile in the process of the body

In humans, under the liver is a small sac called the gallbladder. It is he who serves as an accumulating vessel, from where the release of biological fluid occurs during food intake. As soon as food enters the stomach, a substance is released from the gallbladder, which then passes into the duodenum and simplifies the mechanism for digesting food.

The main functions of the bile secretion:

• stimulation of the process of digestion of food, improvement of intestinal motility;
• promotes better absorption of nutrients, vitamins;
• the breakdown of fats and the removal of various toxins and other decay products.

By itself, the liquid is dark brown, yellow or greenish in color, and tastes bitter. If the gallbladder is disrupted and bile stasis occurs, such a violation can be identified by a number of specific symptoms:

• bitterness in the mouth (even on an empty stomach);
• possible vomiting of bile, which occurs, as a rule, with an empty stomach (signals a strong accumulation of secretions);
• pain in the right hypochondrium;
• nausea;
• itching of the skin and feet;
• yellow skin tone;
• periodic swelling in the neck and chin area;
• problems in the throat (tickle, hoarseness, belching);
• whitish coating on the tongue;
• discomfort in the region of the heart (especially after eating);
• chronic fatigue;
• nervous state and exacerbation of fears (mainly at night).

Ignoring the symptoms can only aggravate the disease and lead to consequences such as the appearance of sand and stones in the bladder.

Causes of the disease

The main detrimental factors that directly affect the functioning of the gallbladder include:

• increased nervousness,
• instability of the emotional background;
• consumption of cholesterol food;
• unbalanced diet, lack of a rational diet;
• very low physical activity;
• excess weight;
• taking specific medications;
• weak abdominal muscles.

Here I would like to separately analyze such a cause of a violation of the outflow of bile as an inflection of the gallbladder. Cholagogue drugs with this diagnosis are also prescribed. But first, about the pathology itself.

So, the inflection of the gallbladder is a common pathological condition of the anatomical shape of the organ. As a result, there is a violation of the functions of the organ - a decrease in synthesis and a deterioration in the excretion of secretions, stagnation of bile, and so on.

The inflection can be congenital (the onset of the pathology occurs in the fifth week of the gestation period, when this organ is formed in the embryo) or acquired. And if in the first option it is hardly possible to do something to prevent pathology, then in the second option, the person himself is often guilty.

Causes of acquired inflection in an adult:

• an increase in the digestive organ or nearby (kidneys, liver);
• bladder hypermobility;
• disturbed (or its complete absence) diet - either starvation or overeating;
• the use of fatty, spicy and smoked foods;
• bending under the influence of physical exertion, in particular weight lifting, a fixed state in a sitting position, sharpness of movements;
• obesity;
• the use of alcoholic beverages (especially carbonated);
• omission of internal organs with a sharp weight loss (due to diets as well).

Usually, in violations caused by such a cause, no list of symptoms is distinguished. But if the deformation of the organ is obvious, then the signs include:

• constipation/diarrhea;
• loss of appetite;
• bouts of nausea/vomiting;
• heartburn/belching;
• bitterness in the mouth;
• pain in the right hypochondrium;
• bloating and heaviness after meals;
• increased sweating.

At the same time, dull pain can radiate not only to the right side, but also to the collarbone, spine, and even to the cervical region.

The degree of excesses is also different, and depending on the neglect of the condition, symptoms may intensify. An accurate diagnosis can only be carried out by a specialist.

Treatment of stagnant bile

When there is a malfunction in the gallbladder and the removal of its secret, it is necessary to consult a doctor to determine the cause of the disease and eliminate it.

As medical practice shows, specialists use complex therapy, combining diet, physical culture and taking choleretic drugs.

Medicines are designed to eliminate pain syndromes, simplify the mechanism of throwing the substance, prevent the recurrence of the disease, and also block secondary pathologies.

Choleretic drugs prescribed for bile stasis are classified into three groups:

• cholespasmolytics;
• cholekinetics;
• choleretics.

Each group of the listed is prescribed depending on the mechanism of action of the active substances, as well as depending on the method of application of the drug.

Group of cholespasmolytics

Medicines in this group have a different origin and are aimed at reducing spasms (tonus) in the gallbladder and bile ducts (including intrahepatic ones), facilitating the excretion of bile into the intestines.

These choleretic drugs are prescribed for stagnation of the secretion and are designed to:

• reduce spasms of the biliary tract;
• reduce spasms of the sphincter;
• eliminate pain in the liver;
• improve the process of excretion of bile during spasm of some areas.

Cholespasmolytics are usually prescribed as an immediate aid for various diseases of the liver and nearby organs. Such drugs are taken in short courses. Their main goal is to relieve pain during increased activity of the smooth muscles of the digestive tract. indications for use:

• cholelithiasis;
• hepatic colic;
• impaired motility of the biliary tract;
• cholangitis;
• cholestasis;
• cirrhosis of the liver;
• pain spasms due to enlargement of tumors.

In this group, drugs are divided into subgroups:

• vegetable - "Holagol" and various tinctures: mint, St. John's wort, lemon balm, calendula flowers, arnica, elecampane, etc.;
• artificial (derived synthetically) - "Papaverin", "Aminophylline", "Duspatalin", "Drotaverin", as well as their analogues;
• which block or weaken the effect of acetylcholine, which is responsible for the presence of excitation of the nervous system) - "Atropine", "Metacin", "Platifillin", "Besalol", "Spazmolitin".

Group of cholekinetics

Cholagogue preparations of this group are designed primarily to restore the function of contraction of the bile ducts, thereby returning the increased tone of the bladder. Such funds are prescribed for chronic forms of cholecystitis and hepatitis, gastritis (provided that the level of hydrochloric acid secretion is zero or lowered), before duodenal sounding.

Which of this group is prescribed for bile stasis? Cholagogue preparations "Berberis plus", "Sorbitol", "Xylitol", "Holosas", "Flamin", "Mannitol", "Magnesia".

Choleretic group

• cholestasis;
• violation of the stool (constipation);
• chronic form of liver diseases (steatosis, hepatitis);
• chronic inflammatory processes and biliary dyskinesia.

Choleretics are also divided into subgroups depending on the origin:

• True - these preparations include an extract of natural bile from animals, plant extracts and biologically active substances of animal origin. The most famous means: "Hologon", "Aplohol", "Holenzim", "Liobil".
• Artificial (they are based on components that were chemically derived) - combined drugs that have antibacterial, antispasmodic and antiphlogistic effects. Representatives of this subgroup: "Osalmid", "Tsikvalon" and "Nikodin".
• Vegetable (with choleretic action) - aimed at reducing the viscosity of the bile secretion, activate its secretion and emissions. At the same time, they affect the functioning of the liver, bringing it to normalization. The list of choleretic herbal preparations of this subgroup is quite large, but the most popular are Hofitol, Febihol, Insadol, Travohol.

They also distinguish a type of medicinal medicines that are designed to reduce the index of supersaturation of bile with cholesterol. Such funds are prescribed mainly for the prevention of the formation of stones in the gallbladder, in addition, they help to dissolve existing ones. Bright representatives of this group: "Ursolit", "Ursodeks", "Urdoks" and "Livodex".

Also, choleretic drugs are divided according to the method of application, regardless of the group. Here the gradation occurs according to the principle of taking the medicine, that is:

• on an empty stomach, 15-30 minutes before a meal (this category includes all drugs, tinctures, decoctions of plant origin) - can stimulate the secretion of the food glands;
• during meals - preparations with gastric juice substitutes;
• after meals - preparations with bile substitutes.

And here a very important nuance will be precisely the time period for taking medications. It is recommended to drink the remedy at the same time. Do not worry: each drug has its own instructions for use, which clearly spells out the intake algorithm.

Therapy of an acquired disease

If the bend is congenital, there is no particular need for therapy. The patient can even live with such a diagnosis all his life and not experience any discomfort. But a person with an acquired form of the disease without fail needs treatment.

In case of inflection, choleretic drugs are prescribed with antispasmodic and choleretic effects. Only a doctor can choose an effective treatment program, taking into account the course of the disease and the individual characteristics of the patient. At the same time, the program should be comprehensive and include, in addition to medicines, physiotherapy, physiotherapy exercises and a special diet.

What drugs to take for biliary inflection? There are a lot of choleretic drugs, so we list only those that doctors usually prescribe to their patients:

• "Gepabene". The main goal is to support liver functions, remove bile secretions, and relieve pain.
• "Allohol" - its basis is cattle bile, nettle and garlic extracts, which stimulate the production of fluid in the gallbladder and improve the function of the ducts.
• "Flamin" is a complex drug with antibacterial, anti-inflammatory, choleretic, analgesic and antispasmodic effects.
• "Odeston" is an excellent remedy that relieves pain syndromes, promotes the release of bile secretions, but has side effects and contraindications, which must be taken into account before starting to use the drug.
• "Hofitol" - helps to organize the protection of the liver, eliminate the stagnation of bile, and also relieves pain.

Ursofalk (and its analogues) is often prescribed for choleretic drugs. But it is usually taken in cases where gallstones are found.

Cholagogue preparations for children

It should be borne in mind that the treatment of gallbladder diseases in an adult will differ significantly from the treatment of children. And not every drug is suitable here.

In general, medical practice tries to exclude such cases when children under 12 years of age are prescribed medications to improve the outflow of bile. By the way, like pregnant women. But if the situation is such that drug therapy will do more good than harm, they resort to taking medication. The doctor will calculate the dosage individually based on body weight and the condition of the baby.

So, with problems with the bile, a small patient will be disturbed by symptoms that are almost similar to those observed in adults, namely:

• loss of appetite;
• the presence of a whitish coating on the tongue;
• loose stools/constipation;
• nausea and vomiting;
• belching with an unpleasant odor;
• bitterness in the mouth;
• very poor tolerance to physical activity;
• headaches, fatigue and apathy;
• pain in the right side, etc.

If, after the examination, the ailment is confirmed and the baby cannot avoid taking medications, you should still know what choleretic drugs are not forbidden to him. The choice is not so small.

For example, Holaflux is a herbal choleretic drug that is prescribed for chronic forms of cholecystitis, disruption of the bladder and its ducts. Helps facilitate the flow of bile. They release this medicine in the form of a herbal collection so that you can prepare it in the form of tea (which makes it very easy for the baby to take the medicine). Instructions for use confirms its safety, since the drug has no side effects.

But the herbal preparation "Cholagogum" can be prescribed to eliminate the main symptoms, and during recovery after therapy. It is produced in capsules, which contributes to the rapid dissolution of active substances directly in the stomach.

What else helps the outflow of secretion during stagnation? A good choleretic drug is Allohol. Also a natural remedy. It affects the functioning of the liver, improving the release of bile. In addition to herbal ingredients, it contains dry animal bile.

"Holenzim". Combined preparation that contains enzymes that promote digestion. It includes, like the previous preparation, dry animal bile mixed with herbs.

"Flamin". This drug is simply the favorite of many parents who confirm its effectiveness. The composition of the herbal preparation includes immortelle, which stimulates the release of fluid from the bladder. The forms of its release simply have no boundaries: ointments, tablets, teas, suspensions. Parents also emphasize that this medicine should still be taken from 5 years.

Barberine tablets are contraindicated only for pregnant women. A herbal remedy is produced in tablets, which include the active substances of the roots and leaves of barberry. Choleretic agent with antispasmodic effect.

"Odeston" is prescribed for children over the age of 10 years. A wonderful herbal medicine that comes in the form of tablets. Its task is not only the synthesis and release of bile secretions, but also the prevention of the formation of cholesterol plaques.

Medicines for pregnant women

In cases where a woman is carrying a fetus, choleretic drugs during stagnation in the liver are selected with the exception of the possibility of stimulating uterine contractions. An equally important nuance is the possibility of transporting the drug through the placental barrier.

Doctors usually prescribe such drugs: Holosas, Atropine, Papaverine, magnesia and valerian are also in demand.

Forms of drug release

The bulk of the choleretic drugs taken during stagnation of bile in the gallbladder is presented in the form of tablets and herbal preparations. But there are other dosage forms: suspensions and powders.

The group of suspensions includes such drugs:

• "Holosas" - is produced in the form of a viscous syrup of a brown (dark yellow) hue. The suspension has a very pronounced rosehip aroma, since the active substance of the drug is the fruits of this plant. The excipient is sucrose. The drug is contained in dark glass bottles of 130 and 300 ml.
• "Ursofalk" is a homogeneous suspension of white color, which has a persistent lemon flavor. Small air bubbles are acceptable. The active ingredient is ursodeoxycholic acid. It goes on sale in dark glass bottles, the volume is 250 ml.
• "Hofitol" - a thick water-based solution, which includes an extract of the leaves of the field artichoke (active substance). Has an orange scent. The drug solution also goes on sale in a dark-colored glass container with a volume of 120 ml;
• Cholagol is a medicine in the form of drops that are taken orally. The volume of a dark glass bottle containing a drop solution is 10 ml. Comes with a dropper dispenser. The composition of the drug includes several active ingredients, such as: essential oils of mint and eucalyptus, frangulomodin, turmeric root, magnesium salicylate. The peculiarity of these drops lies in the method of taking the drug - before eating, you need to drop up to 10 drops per 1 piece of refined sugar (and so three times a day). With severe colic, the dose can be increased to 20 drops at a time.

What other choleretic drugs exist? With stagnation of bile in the gallbladder, doctors often prescribe medicines in powder form, for example:

• "Decholin" is a drug in the form of a colorless powder that is highly soluble in water. It tastes bitter. The volume of the sachet is 5 g. Also on sale you can find 5-20% solutions for intravenous injections. The solution has a slightly alkaline reaction. Able to increase the secretion of bile within 3 minutes, maintaining its effect for about 3 hours.
• "flamin" - small granules of various shapes of light yellow color (gray with a yellow tint is allowed). It is odorless, but allow for a slightly perceptible specific aroma. The granules are contained in paper packages weighing 1.38 grams. The active substance is flamin (sand immortelle flowers).

Regardless of the form of the drug being produced, it is strongly recommended to seek specialist advice before starting therapy. Only a qualified doctor will be able to prescribe a suitable choleretic drug that will help to cope with the disease. Finally, we list the most popular remedies, based on patient reviews.

The best choleretic drugs

A person suffering from stagnation of bile tries to eliminate the cause of his poor health as soon as possible. Sometimes you can cope with the help of folk remedies, but more often it happens that people do not pay attention to body signals and ignore the first symptoms. In advanced cases, an integrated approach with the use of drugs is required. Of course, we are talking about the safest and most effective choleretic drugs. With stagnation of bile in the liver or gallbladder, the first thing to do is often prescribed Alloloch. Its advantage is a low price, but the effectiveness of this does not decrease. The popularity of the product is due to its natural composition with the addition of animal bile. In addition, "Alloloh" improves the digestive process in general.

"Odeston" is also popular, despite the fact that it belongs to the category of synthetic products. Its active substance is hymecromone, which acts on the mechanism of bile ejection. Prevents the formation of stones in the bladder. But you should be careful when using it, as the drug has a number of contraindications.

But "Flamin" is the idol of those who give their preference to natural and herbal preparations based on various herbs. Its advantage is that it acts in several directions at once: it improves the production of bile, tones the gallbladder, eliminates spasms in the ducts, is able to thin the secret, and has an antibacterial effect. It has a positive effect on the entire functioning of the digestive system. But it has some contraindications, which are also worth considering and discussing with a specialist before starting therapy.

Any of the listed choleretic drugs can normalize the outflow of secretions and the activity of the gallbladder as a whole. But will this effect last? Here, as luck would have it. Do not be treated, hoping for a chance! If you find yourself with symptoms that indicate stagnation of bile, rather contact a medical institution for timely and professional help.