Pseudomonas aeruginosa, nosocomial. Pseudomonas aeruginosa is the causative agent of many diseases of the respiratory system.

Pseudomonas aeruginosa (pseudomonas aeruginosa) causes acute pseudomonas infection. A urine test for the presence of Pseudomonas aeruginosa is considered indicative for detection. Pseudomonas aeruginosa is pathogenic and causes diseases of various body systems. People with reduced immunity, elderly people and children are more often infected. Therefore, timely detection is extremely important.

Pseudomonas aeruginosa in the urinary organs and urine

Bacteria excites various diseases urinary system, entering the body due to:

• surgical interventions;
• examination requiring the use of instruments;
• applications aids, for example, a urinary catheter.

Pathological reasons for the accelerated proliferation of microbes are:

• urolithiasis;
• organ maturation defect genitourinary system(congenital pathology).

Pseudomonas aeruginosa leads to approximately 35% of all diseases observed in the urinary system of the body. The infection can develop over months and years and is chronic. It is carried by the bloodstream from the urinary system. But it can, on the contrary, get into the blood through genitourinary organs

from other parts of the body. An infectious and inflammatory process can occur in transplanted organs, for example, in the kidneys.

Symptoms of infection

Pseudomonas aeruginosa infection can manifest itself as pain in the lower abdomen. Pseudomonas aeruginosa causes the development of diseases in the urinary system, similar to other diseases caused by other bacteria. It is common for a microorganism to cause inflammation that occurs long time with repeated exacerbations: cystitis, pyelonephritis, urethritis. One of the signs of Pseudomonas aeruginosa infection is the formation of ulcers on the surface Bladder

• , ureter or renal pelvis. Visible symptoms of inflammation caused by infection include:
• cutting pain in the lower abdomen;
• frequent bowel movements accompanied by a burning sensation;
• lumbar pain (pulling);
• temperature increase;

detection of Pseudomonas aeruginosa in the urine.

Children are more susceptible to infection than adults. The number of cases of infectious diseases of this type in children is 10 times higher. Infants under 1 year of age are at risk. The route of infection in this group is the umbilical wound. But the route of entry can be either upward or from other infected systems through the bloodstream. Once in the organs of the urinary system, the microorganism causes the same inflammatory processes as in adults (cystitis, pyelonephritis, urethritis).

As in an adult, Pseudomonas aeruginosa causes a long-term illness in a child. A transition to chronic form. One of the symptoms of the development of infection is the appearance of urine that has a greenish tint, since the urinary tract is primarily affected. A child can be a wand carrier for a long time without visible symptoms. But this increases the risk of spreading the bacteria to family members and other children.

To confirm the presence of a stick in the body, it is recommended to conduct a bacteriological examination of blood, urine, nails, mucus from the nose or other biomaterials that will identify the cause infectious inflammation. The material for analysis depends on the system of bacterial infection and the location of the disease. To check the urinary organs, a patient's urine sample is used. Women are shown a smear of the vagina and cervix.

A urine test will help determine the presence of the rod in the human body.

It is advisable to undergo an examination and have your urine tested before starting to use any antibiotics to treat the infection, as this may affect the result. Simultaneously with checking the urine, in which Pseudomonas aeruginosa can be detected, the patient undergoes an antibiogram. During this examination, the sensitivity of the pathogen to a specific set of antibacterial drugs. This will allow you to choose the right therapeutic tactics.

Pseudomonas aeruginosa(lat. Pseudomonas aeruginosa) is a type of gram-negative aerobic non-spore-forming bacteria. Pseudomonas aeruginosa are mobile and have the shape of straight or curved rods with a length of 1 to 5 microns and a diameter of 0.5 to 1.0 microns.

Pseudomonas aeruginosa lives in soil, water, and plants. It is very resistant to the effects of many disinfectants and can multiply in their weak solutions, as well as in distilled water.

Pseudomonas aeruginosa is sometimes found on the skin of the inguinal and axillary areas, in the outer ear canal, upper respiratory tract and colon healthy people.

Pseudomonas aeruginosa in the taxonomy of bacteria

Pseudomonas aeruginosa (type Pseudomonas aeruginosa) belongs to the group Pseudomonas aeruginosa group, which is part of the genus Pseudomonas ( Pseudomonas), family Pseudomonadaceae, order Pseudomonadales, class Gammaproteobacteria ( γ proteobacteria), a type of proteobacterium ( Proteobacteria), kingdom of bacteria.

Pseudomonas aeruginosa - a causative agent of human diseases

Pseudomonas aeruginosa causes up to 15–20% of all nosocomial infections. It is considered one of the main causative agents of nosocomial pneumonia, causes a third of all lesions of the genitourinary system in urological patients and is considered the cause of 20–25% of purulent surgical infections and primary gram-negative bacteremia. Pseudomonas aeruginosa mainly affects people with weakened immune systems with concomitant diseases, the elderly and children. Pseudomonas aeruginosa in medical institutions transmitted through contaminated food or water, as well as through toilets, sinks, water tap handles, objects, especially wet objects, shared towels, and also through hands medical personnel and contaminated, poorly disinfected medical instruments and equipment, therefore hospitalization significantly increases the risk of patients becoming colonized with Pseudomonas aeruginosa and developing nosocomial infections.

In adults and older children, pseudomonas infections of the gastrointestinal tract are characterized by an acute onset, vomiting of eaten food, pain in the epigastric region or around the navel and proceeds as food poisoning with slightly severe symptoms intoxication. Body temperature is normal or elevated to 37–38° C. The stool is mushy or liquid up to 4–8 times a day, with a small admixture of mucus and greens. The condition of patients returns to normal on the 2nd–3rd day of the disease. Appendicitis and cholecystitis may develop.

In children early age enterocolitis and gastroenterocolitis develop more often. The disease begins acutely or gradually and manifests itself as deterioration general condition, increased body temperature to 38–39° C, regurgitation or vomiting and frequent loose stools up to 5–6 times a day (less often up to 10–20). The stool is foul-smelling, with a lot of mucus, greenery, and streaks of blood may be observed. In severe cases, intestinal bleeding develops. Palpation of the abdomen reveals rumbling, bloating and pain small intestine. There are no signs of distal colitis. The leading symptoms are severe intoxication and gradually progressive dehydration of the body. A sluggish, long-term course with frequent exacerbations is possible. In this case, the body temperature usually remains no higher than 38.5 ° C, symptoms of intoxication, bloating and rumbling upon palpation, and the patient’s body weight decreases. Recovery occurs in 2–4 weeks.

Treatment of infections caused by Pseudomonas aeruginosa

Infections caused by Pseudomonas aeruginosa are difficult to treat with antibiotics, due to frequent discharge multiresistant strains. Most effective antibiotics in the treatment of Pseudomonas infection are antipseudomonas cephalosporins (ceftazidime, cefepime), carbapenems (meropenem, imipenem); Combinations of these antibiotics with fluoroquinolones (ciprofloxacin) or aminoglycosides (amikacin) are often used in treatment.

Prevention of Pseudomonas aeruginosa infection is difficult, since Pseudomonas aeruginosa is resistant to the action of many antiseptics and disinfectants. Pseudomonas aeruginosa can exist for a long time in solutions of furatsilin, used for washing wounds and for storing catheters and surgical instruments. Pseudomonas aeruginosa can produce substances that can neutralize some disinfectants. At the same time, it is sensitive to drying, the action of chlorine-containing disinfectants, and quickly dies under the influence of high temperature and pressure.

Antibiotics, active and inactive against Pseudomonas aeruginosa

Antibacterial agents (those described in this reference book) active against Pseudomonas aeruginosa:

Pseudomonas aeruginosa is a conditionally pathogenic bacterium that often resides in the body of a completely healthy person without causing him any harm,

However, when this infection multiplies, it causes various diseases.

Today, dear blog readers, “ ethnoscience ", we will look at the main points regarding Pseudomonas aeruginosa infection. Pseudomonas aeruginosa is often found in healthy people when visiting a medical facility, but there is no need to worry if there are no real symptoms.

Pseudomonas aeruginosa usually likes to settle in the intestines, axilla, parotid and groin areas person. The infectious agent has such characteristic feature– it produces a blue-green pigment. But there are strains that produce red, orange, brown and even black pigments.

Pseudomonas aeruginosa, causes of the disease

The causative agent of the infection is found in the soil, open water bodies polluted by sewage water, and the gastrointestinal tract of birds and animals. This is why there are many sources of infection for a susceptible organism.

Pseudomonas aeruginosa can often be found in medical institutions; the pathogen is highly resistant to many antibiotics and disinfectants (antiseptics).

A large amount of Pseudomonas aeruginosa is released when patients cough, the cause of which is this pathogen. The mechanism of transmission of infection occurs through airborne droplets or household contact through contact with contaminated (infected) towels, door handles, sinks and toilets, and water taps.

When carrying out procedures with medical instruments that are not sufficiently processed and sterilized. When consuming contaminated food products (milk, meat, drinking water).

The infection is activated when the immune system is weakened in those areas where it was previously present in small quantities. For the development of one or more diseases, Pseudomonas aeruginosa requires favorable conditions for intensive reproduction.

Provokes microbial growth high content blood sugar, which occurs in people with weakened immune systems, when taking hormonal corticosteroid drugs (dexamethasone, prednisolone, etc.), anticancer drugs.

With prolonged treatment with antibiotics, the patient often develops, which is also a favorable condition for the presence and reproduction of Pseudomonas aeruginosa.

“Pregnant women, elderly people, AIDS patients and HIV-infected people are most susceptible to infection; children under 5 years of age."

Pseudomonas aeruginosa clinic

The incubation period, which begins from the moment of infection and continues until the first signs of infection are detected, averages from several hours to five days.
Pseudomonas aeruginosa, multiplying in different organs or tissues, causes various diseases.

Actively multiplying and covering new territories, it subsequently breaks down and releases harmful toxins and enzymes that contribute to the death of red blood cells, leukocytes and other cells.

Continuing its aggressive mission, Pseudomonas aeruginosa from the primary source of infection begins to spread through the bloodstream throughout the body.

The most dangerous is damage to certain parts of the central nervous system, which include meningitis and meningoencephalitis, accompanied by profuse vomiting, deterioration of consciousness, motor activity and sensitivity.

Quite often, Pseudomonas aeruginosa affects the ears with the development, while the patient complains of pain in the ear and prolonged purulent-bloody discharge. When the pathogen multiplies in the throat, the patient experiences swelling of the pharynx, redness and pain in the throat, cracks in the tissues, and an increase in body temperature.

When the infection spreads in the nasopharynx and paranasal sinuses, sticky, mucous discharge from the nasal cavity that is difficult to treat appears.
Pseudomonas aeruginosa can cause damage to almost any organ digestive tract, starting from the mouth to the end of the rectum.

Inflammatory processes can be either mild catarrhal or ulcerative-necrotic with phenomena of perforation of the intestinal wall, bleeding and even peritonitis.

Symptoms of Pseudomonas aeruginosa

The clinical picture of the disease is different. It depends on the site of localization of the inflammatory process: patients complain of decreased appetite, general weakness, spasmodic pain in the abdomen, frequent stools from four to eight times a day of a pasty or liquid consistency with the release of greens and (or) mucus.

When the disease is mild, it lasts from two to four days. However, there may be some complications: dysbacteriosis and appendicitis. Wounds on the surface of the skin affected by Pseudomonas aeruginosa are characterized by a bluish-green discharge that stains the dressing material.

In severe cases, a dark brown, purple or black scab forms on the wound surface, under which necrosis and hemorrhages in the tissue are hidden. The process may result in the formation of an abscess and even. Acute renal failure And .

Skin damage is expressed by the appearance of painful red nodules, reaching up to one centimeter in diameter. After a few days, these pustules open on their own.

When organs are damaged, Pseudomonas aeruginosa causes, , t; the urine becomes colored green, and the treatment is long-term. When the pathogen gets under the nail, it causes panaritium.

Diagnosis of Pseudomonas aeruginosa

Without holding laboratory methods studies, diagnosing Pseudomonas aeruginosa is almost impossible, since there is no specific clinical picture, different from similar other infections.

However, it is possible to suspect this infection by observing the protracted course of the disease, the lack of effect of antibacterial therapy, a visible connection with former operation or injury; when identifying a wound, as well as dressing material that has a blue-green color.

The diagnosis is confirmed by bacteriological examination of culture and determination of the causative agent of infection, its sensitivity to antibacterial agents and antibiotics. Cultures are usually examined before conservative treatment with antibiotics is initiated.

For sowing, the material can be purulent discharge from the nasopharynx, wounds, feces, urine, sputum, cerebrospinal fluid (CSF), blood, vomit, smears from the cervix or vagina. It is also used to diagnose Pseudomonas aeruginosa. serological method research - detection of antibodies and antigens to this infection in the blood.

An increase in antibody titer after a repeated (additional) blood test finally confirms the diagnosis of the disease.

Treatment of Pseudomonas Infection

“If a patient is found purulent wounds, panaritium, abscesses, he will require surgical intervention. All patients with purulent processes antibacterial conservative therapy is prescribed"

A good effect is achieved in the treatment of advanced Pseudomonas aeruginosa infection by adding special probiotics - components of the physiological flora of humans, enzymes and sorbents, immunomodulators and detoxification agents.

Antibiotics are usually used both intravenously and intramuscularly. Taking into account sensitivity, antibiotics are prescribed that have wide range actions: ticarcilin, tobramycin, ceftazidime, amikacin, cefoperazone, cefepime. There are also reserve drugs: ciprofloxacin, aztreonam and etc.

"Attention! Treatment with antibiotics (calculating the dose and duration of administration) can only be carried out by the attending physician, who takes into account the sensitivity of the microflora, the individual condition of the patient, the severity of the disease and its form."

The use of bacteriophages is shown ( pyobacteriophage, pseudomonas bacteriophage, intestibacteriophage) after receiving the results bacteriological research cultures for sensitivity in purulent wounds, diseases of the urinary system, the cause of which was Pseudomonas aeruginosa.

The duration of conservative treatment averages from five to fifteen days. If the need arises, it is repeated. Modern medicine has the drug pseudovac. This is a vaccine that is prescribed when there is a high risk of developing Pseudomonas aeruginosa among adult patients with massive burns or severe open injuries.

For the same purpose, it is possible to administer immunoglobulin, as well as hyperimmune specific antipseudomonas donor plasma.
During the treatment of Pseudomonas aeruginosa, the patient is given food, rich in vitamins And minerals, fermented milk products, onions, and viburnum. And . We take all the herbs in equal parts:

» let stand for twenty minutes on low heat 2 tbsp. spoons of the crushed collection in one glass of boiling water, remove from the stove and leave to steep for one hour. We filter the broth and give the patient with Pseudomonas aeruginosa to drink two tbsp. l. on an empty stomach four times a day with a course of treatment of two to four weeks.

Can be used as rinses and lotions alcohol tincture calendula officinalis, oil or alcohol solution horophyllipta, propolis, oil tea tree. All of these drugs can be easily purchased at the pharmacy.

How to cook water solution propolis at home:

» heat half a glass of water to 50⁰C, add 10 g of propolis there, then leave to infuse in a thermos for 12 to 14 hours; We take the prepared infusion orally, 1 teaspoon. before meals, on an empty stomach three times a day, and also applied to areas affected by Pseudomonas aeruginosa. Duration of treatment should not be less than 10 days.

Friends! Pseudomonas aeruginosa is not a death sentence! Timely initiation of treatment leads to complete recovery. Be healthy, God bless you!

Pseudomonas aeruginosa infection is quite dangerous and aggressive, with a high incidence among the population. Up to 20% of all hospital-acquired or nasocomial infections are caused by Pseudomonas aeruginosa. Up to 35% of urinary system infections are caused by this stick, as well as 25% of purulent surgical processes. A quarter of cases of primary bacteremia are also caused by P. aeruginosa.

Pseudomonas infection– spicy infection caused by microorganisms of the genus Pseudomonas, affecting the respiratory system, gastrointestinal tract, soft fabrics, nervous and other systems of the body.

Pseudomonas aeruginosa (Pseudomonas aeruginosa)– an opportunistic microorganism of the genus Pseudomonas (pseudomonas). It is a gram-negative (Gram stain does not produce a purple stain) rod-shaped bacterium with rounded ends, 0.5 to 1 µm in size.

It is mobile, does not have a dense capsule, does not form spores. It is an obligate aerobe (reproduces with access to oxygen and high humidity). During bacteriological examination, it grows on special nutrient media (meat-peptone agar - MPA, meat-peptone broth - MPB and others), where, as it grows, bluish-greenish colonies with a glow (fluorescent) appear, smelling of jasmine. It has somatic O- and flagellar H-antigens, as well as a capsular K-antigen. The H-antigen (flagellate) allows the isolation of about 60 serovars of Pseudomonas aeruginosa. It is quite resistant to the action of many disinfecting solutions, in some of which it can multiply. Only a 5% solution of chloramine, a 3% solution of hydrogen peroxide and a 2% solution of phenol (carbolic acid) have a detrimental effect on it. In nature, it is found in soil, open water, and on plants. Optimal temperature growth 37°C.

Pseudomonas aeruginosa can be pathogenic for humans. Often occurs when inflammatory processes(purulent wounds, abscesses), often causes infections urinary tract and intestines. Causes with high frequency nosocomial infections due to its prevalence in people with immunodeficiencies ( chronic diseases, surgical interventions, infections and others). Pseudomonas aeruginosa can be found in the human respiratory tract, large intestine, external auditory canal, as well as on the surface of the skin in the folds (axillary, inguinal). With normal immunity, Pseudomonas aeruginosa encounters competitive resistance from representatives of normal flora, which suppress its growth and cause death (for example, in the intestines).

The pathogenicity factors of Pseudomonas aeruginosa are:
1) motility due to flagella;
2) the ability to produce toxins (endotoxin, exotoxin, endohemolysin, leukocidin enzyme), which cause damage to red blood cells, liver cells, triggering intoxication, and death of leukocytes in foci;
3) high row resistance antibacterial agents due to the ability to form a mucus-like capsule around its colonies - glycocalyx (in particular, it is resistant to beta-lactams, aminoglycosides, fluoroquinolones), which complicates effectiveness therapeutic measures in such patients.

Causes of Pseudomonas aeruginosa infection

Source of Pseudomonas infection– humans and animals, both patients and carriers of Pseudomonas aeruginosa. Patients with pneumonia and open purulent wounds bear the greatest risk of infection.

Routes of infection– this is contact-household, airborne, food. Transmission factors – food products(milk, meat products), water, as well as environmental items (usually hospital) - sinks, taps, faucet handles, doors, toilets, shared towels, hands of medical staff and poorly processed medical instruments. It is these common factors that explain the high risk of infection with Pseudomonas aeruginosa during hospitalization and the occurrence of nosocomial infections. The risk group for Pseudomonas aeruginosa infection consists of burn hospitals, surgical departments hospitals, obstetric and pediatric hospitals. Even epidemic outbreaks of Pseudomonas aeruginosa infection can occur here (if the sanitary and epidemiological regime of the departments is violated).

Patients with reduced immune protection due to concomitant acute or chronic diseases, as well as certain age groups - elderly people and children. Children are many times more likely to suffer from this infection. The most vulnerable children groups are newborns and children in the first 2-3 months of life, as well as premature babies.

Risk groups for developing Pseudomonas aeruginosa infection
No. Patients with certain conditions Possible manifestations Pseudomonas aeruginosa infection
1 Frequent intravenous procedures Osteomyelitis, endocrditis
2 Leukemia Sepsis, perirectal abscess
3 Malignant growth diseases Pneumonia
4 Burns Sepsis, cellulitis
5 Operations on the central nervous system Meningitis
6 Tracheostomy Pneumonia
7 Corneal ulcers Panophthalmitis
8 Vascular catheterization Purulent thrombophlebitis
9 Catheterization urinary tract Infections of the genitourinary system
10 Neonatal period Meningitis, diarrhea

Stages of occurrence of Pseudomonas aeruginosa infection

Infection and the occurrence of infection occurs in 3 stages:

1) attachment of Pseudomonas aeruginosa to the damaged tissue and its reproduction at the site of attachment, that is, the primary focus of infection;
2) spread of infection into deep tissues - the so-called local infection (it is still restrained by the immune system);
3) penetration of the pathogen into the blood with the development of bacteremia and spread of infection to other organs and tissues (septicemia).

Symptoms of Pseudomonas Infection

Pseudomonas aeruginosa can cause inflammation of many organs and systems; we will consider only its most frequent manifestations.

Pseudomonas infection gastrointestinal tract characterized by the appearance acute enterocolitis or gastroenterocolitis. The severity of the manifestations depends both on the patient’s age and on the initial state of the immune system and the intestines themselves. Thus, in older children and adults, an acute onset with vomiting, pain in the stomach (epigastric region), and then throughout the abdomen, weakness, poor appetite, nausea, temperature is often low-grade (up to 38°), stool up to 5-7 times. per day, mushy, with pathological impurities (mucus, blood), brownish-greenish in color. The duration of the illness is no more than 3-4 days. Children of early childhood experience a more severe infection - higher temperature (up to 39°), frequent regurgitation or vomiting, refusal to eat, lethargy, frequent loose stool up to 6, and sometimes up to 10-15 times a day, the stool is also greenish with pathological impurities (mucus, blood), has a characteristic fetid odor, bloating, loud rumbling. Along with the acute course, there are variants with mild symptoms, but the disease itself lasts up to 4 weeks. Feature in early childhood– the risk of developing intestinal bleeding, dehydration, and at an older age – appendicitis and cholecystitis. Concomitant disease with intestinal damage – the development of dysbiosis, which requires long-term therapy during the rehabilitation period.

Pseudomonas aeruginosa urinary tract infection(MVP) is manifested by the occurrence of cystitis, urethritis, pyelonephritis. Infection occurs in the urinary system more often during catheterization of the bladder. Symptoms of specific diseases are similar to those of other infections. In most cases, UTI infection occurs chronically over several months or even years. In rare cases, infection from this primary focus spreads to other organs and tissues.

Pseudomonas infection respiratory system often develops against the background of a chronic bronchopulmonary disease (bronchitis, cystic fibrosis, bronchiectasis); patients in intensive care units and intensive care(on artificial ventilation lungs, after endotracheal intubation). It is possible to develop both primary pneumonia and secondary pneumonia, which is characterized by a protracted course, poor effectiveness of antibacterial therapy, and a tendency to destructive processes. Symptoms of pneumonia are similar to those of other infectious lesions lungs.

Pseudomonas aeruginosa infection of soft tissues and skin occurs in places of open wounds, burn surfaces, wounds after surgical interventions, trophic ulcers on the limbs. You can understand that a pseudomonas infection is developing by the discharge from the wound, which becomes blue-green in color. This is the color the patient’s wound dressing will be.

Also with wounds it is possible to develop pseudomonas osteomyelitis(damage to bone tissue).

Pseudomonas ear infection manifests itself in the form of purulent external otitis, in which there is pain in the ear, purulent discharge mixed with blood, and less often develops otitis media and mastoiditis (inflammation of the mastoid process).

Pseudomonas aeruginosa eye infection develops as a result of eye surgery or traumatic injury. Purulent conjunctivitis may develop, damage to the cornea and the eyeball. At the same time, patients feel foreign body"in the eye, pain, blurred vision, purulent discharge.

Pseudomonas aeruginosa infection of the nervous system occurs in neglected patients and is one of the severe manifestations of this disease. Meningitis (inflammation of the soft tissue) may develop meninges), meningoencephalitis (damage to the brain substance). In most cases, the infection is introduced from the primary focus during a septic process. Primary reproduction of Pseudomonas aeruginosa is in the central nervous system possible after injuries and surgical interventions. Typical picture purulent meningitis or meningoencephalitis, which is practically no different from other infections. With lumbar puncture - a high content of cells in the cerebrospinal fluid (pleocytosis) up to several thousand per ml, a predominance of neutrophils over lymphocytes, a high protein content, the liquid when flowing out is cloudy with greenish flakes. The prognosis is often unfavorable.

Other manifestations of Pseudomonas aeruginosa infection include endocarditis (damage to the cardiovascular system), arthritis, sinusitis, frontal sinusitis, sinusitis and, finally, sepsis - a generalized Pseudomonas aeruginosa infection affecting many organs and systems.

Summarizing the above, we can highlight the important features of Pseudomonas aeruginosa infection:
- At acute course high frequency of adverse outcomes due to the high resistance of P. aeruginosa to a number of antibacterial drugs, which creates difficulties in treatment and causes lost time.
- Tendency to protracted and chronic infection with frequent relapses varying degrees severity, which requires long-term treatment.

Diagnosis of Pseudomonas aeruginosa infection

1) Preliminary diagnosis is difficult because clinically specific symptoms For
There is no Pseudomonas infection. Warning factors regarding P. aeruginosa are the protracted course of the infection despite the ongoing antibacterial therapy, which is not successful, as well as the connection between the occurrence of infection and medical manipulations in hospitals, surgical interventions, injuries.

2) The final diagnosis is made after laboratory examination. Lead method
examination - bacteriological followed by bacterioscopy. The material for research can be any depending on clinical form– from nasopharyngeal mucus and feces to urine, cerebrospinal fluid discharge from wounds. It is advisable to collect the material before the start of the antibacterial study. The material is inoculated on a special nutrient medium, where blue-green colonies with fluorescence are grown, and then they are examined under a microscope.

P. aeruginosa colonies

Pseudomonas aeruginosa during bacterioscopy

Usually, another study is immediately carried out - an antibiogram (determination of sensitivity to certain antibacterial drugs).

An additional research method is serological blood testing for antibodies to P. aeruginosa, which is used mainly retrospectively (that is, to confirm infection).
General clinical methods (urinalysis, blood analysis, biochemistry, etc.), as well as instrumental methods The studies help the doctor to diagnose only the clinical form of Pseudomonas aeruginosa infection.

Treatment of Pseudomonas Infection

1) Organizational and routine measures are reduced to hospitalization of patients with severe manifestations of infection in any hospital according to the profile. Bed rest for the entire period of intoxication.

2) Drug treatment.
Etiotropic therapy is quite complex for Pseudomonas aeruginosa infection.
The frequency of occurrence of antibiotic-resistant strains of P. aeruginosa is high. Despite this, there are certain groups antibacterial drugs or their individual representatives within the group, which have retained their effectiveness during Pseudomonas infection. These include some cephalosporins (ceftazidime, cefepime), carbapenems (imipinem, carbapinem), a modern aminoglycoside (amikacin), and some fluoroquinolones (ciprofloxacin). P. aeruginosa has been proven to be resistant to tetracyclines and rapidly develop resistance to fluoroquinolones (levofloxacin and others).

Pathogenetic therapy and syndromic therapy are prescribed depending on clinical manifestation Pseudomonas infection.

Prevention of Pseudomonas aeruginosa infection

Basic preventive actions are reduced to the prevention of immunodeficiencies ( timely treatment chronic diseases, chronic infections), prevention colds. Prevention of infection in children, for which the parents themselves are sometimes to blame (promoting the baby’s health, monitoring nutrition, water consumption, swimming in open water). Prevention of nosocomial transmission of infection usually depends only on medical personnel.

Infectious disease doctor N.I. Bykova

Pseudomonas aeruginosa is not only often found in nature, but also lives in the human body. However, if there are more bacteria than usual or a decrease in the level of immunity, the possibility of various types of ailments arises.

The overall picture of the disease varies - everything depends on which organ is affected. Treatment should be carried out strictly under the supervision of a doctor, but attempts to cure yourself can lead to complications or even death.

Treatment of Pseudomonas aeruginosa with antibiotics

For complex treatment you will need to take antibiotics anyway. But before starting treatment, the doctor will send you for a test to determine the causative agent of the disease, as well as its reaction to antibacterial drugs.

Depending on the type of disease and location of the disease, a person must donate urine, blood or mucus. Antibiotics are usually prescribed, which are injected intravenously, most often into the arm, and then intramuscularly into the fifth point or another part of the arm.

At the same time, treatment is carried out for those parts of the body that are directly affected by Pseudomonas aeruginosa. When this bacterium appears in the urine, it is necessary to administer antibiotics and antiseptics through a catheter, but if the mucous membrane or skin is affected, it is worth treating them with sprays and aerosols, as well as treating these areas with special ointments and creams.

Treatment of Pseudomonas aeruginosa in the intestines

Infrequently, Pseudomonas aeruginosa can affect the stomach. The first signs of the disease may be vomiting, pain in the intestines, and rare bowel movements. These symptoms can be confused with the appearance of bacteria with a simple infection.

But rapid dehydration of the body will still indicate serious illness, excited by Pseudomonas aeruginosa. For treatment, the doctor will prescribe cephalosporins ( Cefepime, Ceftazidime), and:

• Meropenem;
• Imepenem;
• Ciprofloxacin;
• Amikacin.

Treatment of Pseudomonas aeruginosa in the ear

This infection can also affect the ears. Bacteria can cause of varying complexity otitis media But, in addition to pain in the ear, various purulent or bleeding. To combat infection, antiseptics are used and penicillin antibiotics fifth and sixth generation. Among the drugs that are most often prescribed are the following:

• Cefzulodine;
• Ceftazidime;
• Carbenicillin.

For ear infections, when they appear purulent discharge, they use a turbunka lubricated with Bacteriophage - a drug that can destroy bacteria by dissolving. Such turundas are inserted into the ear several times a day for 1 hour.

Treatment of fistulas with Pseudomonas aeruginosa

When fistulas caused by Pseudomonas aeruginosa appear, antibiotic injections are prescribed into the affected area. Aspergin, a biological antibiotic that fights not only Pseudomonas aeruginosa, but also destroys some other pathogenic microorganisms, began to be used especially often.

Treatment of pseudomonas infection with folk remedies

If the manifestations of the disease are not too acute, you can use traditional methods and means for treatment. It would be nice to use the complex folk remedies, supplemented with antibiotics. The most noticeable effect on the bacterium is decoctions of rose hips, horsetail, viburnum and others. For cooking medicinal decoction necessary:

Pour boiling water over a tablespoon of herbs or berries, then after cooling, heat in a water bath, and then dilute the concentrate with boiled water (0.5 liters). Take the drug half a glass several times a day.

Plantain, which is commonly used for wounds, can also help treat Pseudomonas aeruginosa. It is enough to squeeze the juice from its leaves.

At home for local treatment use a 1-2% solution boric acid for rinsing the mouth and throat, washing the eyes, ears or channels.