Are menthol, phenobarbital and ethyl alcohol. Each of these substances has special properties, so the drug is considered universal in use, but you should not drink it for a long time. Ethyl alcohol has an antispasmodic effect on the body, calms the nervous system and relieves psychological stress. Menthol has a rapid expansion property blood vessels. Phenobarbital has a sedative effect on the internal organs of a person, while relieving the body of pain.

Phenobarbital is part of Corvalol in small quantities. It is a mistake to consider the drug a narcotic drug, but it must be used with great care.

Studies of the drug by doctors show that it can be not only, but also harmful to the body. There are several serious negative properties corvalol associated with a side effect of its constituent components. Ethyl alcohol, for example, causes rapid organism. According to doctors, if you abuse this drug, drink for a long time, then it will affect a person like a synthetic drug. In addition, ethyl alcohol should be used only in minimal dosages. Otherwise, instead of fighting insomnia, there will be reverse effect drowsiness and physical weakness.

mint oil, which is part of Corvalol, is also not always useful. If the dosages are exceeded, it can cause disruption of some systems in the body and cause. People with individual intolerance to this component may experience allergic reactions. In rare cases, doctors categorically forbid patients to take Corvalol, recommending replacing it similar drugs. For example, coping with disorders nervous system no worse than its competitor, but it does not contain phenobarbital. This drug instead of Corvalol, but in no case should they be combined.

Corvalol has only a temporary effect on the body. The drug is able to calm the nervous system, but cannot eliminate heart disease. Stabilization of well-being should not be the reason for refusing the examination.

side effects of corvalol

Corvalol should be used in strict accordance with the instructions. If the dosage is exceeded or it is used too often, serious complications can occur. The most common of them are memory disorders, speech disorders, general physical weakness. If after taking Corvalol the desired effect does not occur, then it is likely that your body is used to the components of the drug. To prevent harmful effects it is better to refuse such a method of treatment for a while.

Quite often there are publications of narcologists in which doctors express the opinion that Corvalol is a real drug. Feedback from doctors should be taken into account. However, such conclusions are made mainly only taking into account the fact that recently the government of the Russian Federation has introduced phenobarbital, which is part of Corvalol, into

Corvalol, validol, noshpa - are perceived by us as completely safe and harmless medicines. There are almost no contraindications. Corvalol is undesirable to take only with renal and hepatic insufficiency. Moreover, pregnant and lactating women should drink it carefully.

Such soft instruction as if suggesting that poisoning with this medicine is impossible. But it is not so. Any medical preparation in the right doses, it heals, and in the wrong doses, it cripples. Corvalol is no exception. And the habit of our citizens to take drops for a reason and without many makes them simply addicted to a light drug, which is this medicine.

Consequences of an overdose of Corvalol

Corvalol is a mild sedative, moderately antispasmodic and hypotensive agent. The correct dose is 15-30 drops three times a day. Drink with water, drip on sugar. What happens if this dose is exceeded? Can an overdose of Corvalol kill? And after what dose come unpleasant consequences?

Phenobarbital is the basis of the drug. Bromisovaleric acid in the form of ethyl ester - excipient. Caustic sodium. Oil peppermint. Distilled water.

Phenobarbital - chemical compound, with a calming effect. There is very little in the preparation. It is addictive, which means that the dose has to be increased all the time. Bromisovaleric acid and peppermint oil increase the effects of phenobarbital.

Ethyl bromisovallerianate is also not a completely harmless substance. It contains bromine, which, if taken for a long time, causes poisoning. With a significant excess of the dose, the consequences can be severe:

• lung diseases;
• unmotivated depression;
• allergies of unknown etiology;
• the clarity of consciousness disappears;
• apathy.

What dose can cause a person to overdose

Half of the vial is critical for simultaneous administration. A daily dose of more than 150 drops will be dangerous. At the same time, you can take no more than 40 drops.

Elderly or childhood and availability chronic diseases lower the threshold at which we have poisoning.

Consequences from an overdose of Corvalol and signs

Let's talk about the symptoms of an overdose of Corvalol. Symptoms of intoxication are divided into three degrees of severity.

In its mildest and most benign form, drug poisoning looks like general weakness unknown origin. Observed the following symptoms: lethargy, fluidity of thoughts, slight inhibition of actions and speech, drowsiness. Unpleasant phenomena can go away by themselves, even if you do nothing, but simply reduce the dose, or completely stop the drug.

The picture of average intoxication looks much less attractive. . The pathological nature of the condition is already visible to the naked eye, and the symptoms are threatening:

• it is impossible to wake a person, sleep lasts unnaturally long;
• salivation;
• muscle weakness;
• blood pressure is reduced;
• a small amount of urine.

Such poisoning requires medical intervention. Necessary measures for intoxication of the body.

A severe degree of intoxication with Corvalol ends in a barbituric coma. Pathological phenomena grow very quickly and often lead to death. Heart failure rapidly increases, wheezing appears, and blood pressure drops sharply. A person begins to turn blue starting from the nasolabial triangle and ending with the cyanosis of the whole body. The heart is working intermittently, which leads to pulmonary edema.

Effect of alcohol on symptom severity

Alcohol enhances the effect of phenylbarbital.

With simultaneous use with alcohol, symptoms of an overdose of Corvalol may occur even at a dose that is significantly less than the critical norm.

This should be taken into account when you go to any holiday where you plan to drink alcohol. In order not to risk earning double intoxication, you should temporarily stop taking the drug or replace it with another one.

Possible causes of overdose

The medicine is taken in order to improve your condition, not worsen it. How then does an overdose of Corvalol occur? Addiction to phenobarbital and as a result, a constant increase in the dose. Combination with alcohol. Simultaneous use of Corvalol and other sedatives or tranquilizers. Strong stress. At nervous breakdown a person may not be aware of how much medicine he drank. Deterioration of the general somatic condition. A weakened body can perceive a normal dose as critical. Symptoms of intoxication will appear.

First aid for an overdose of Corvalol?

What to do if you find symptoms of an overdose in a person? Try to determine the severity of intoxication. At the very mild degree- immediately wash the stomach. Washing should not be completed until clear liquid. Take medicines that remove toxins from the body: Activated carbon, other sorbents, enterosgel. They will help reduce the effects. Consult a doctor. No one can guarantee that the patient's condition will not worsen. In moderate and severe cases, the doctor should be called immediately. While the ambulance is coming, lay the person on the floor, release the chest from excessive compression by clothing and turn the head to one side. It is undesirable to do intoxication measures in such cases, since the consequences can be irreversible.

In small doses, Corvalol is safe, and it helps to cope with minor and not very ailments of the body. But they should not be abused. Any medical remedy can bring both improvement and harm to health. Everything depends on the dose.

Corvalol poisoning

Corvalol is present in almost every home first aid kit. Many consider him universal remedy from pain in the heart anxiety states and also for comfort. Frequent use Corvalola, by different reasons and in large doses, can have serious consequences.

What awaits the "lovers" of Corvalol? How much should you drink to be poisoned? What are the symptoms of an overdose? What to do in case of Corvalol poisoning? All this, as well as the rules for first aid and treatment, will be discussed further.

Is it possible to get poisoned by Corvalol and due to what does this happen? You can get poisoned and this happens due to the barbiturate contained in it. long-acting- Phenobarbital.

How many drops of Corvalol do you need to get poisoned? Maximum dose the drug per day can reach up to 150 drops. In case of violation of the activity of the kidneys, as well as in the elderly, it can already cause intoxication. Incorrect selection of the dose to the child also threatens with poisoning. The cause may be anxiety-depressive disorders, and other causes when the maximum dose is exceeded.

Symptoms of Corvalol poisoning

In Corvalol poisoning, symptoms can be mild, moderate or severe.

What to do in case of Corvalol poisoning

In case of Corvalol poisoning, what can be done at each stage of poisoning, how to provide first aid?

In case of mild intoxication, gastric lavage is carried out to clean washing water, the intake of any sorbent available at hand, taking into account the absence of its intolerance, is calculated as one third of the maximum daily dose. At this stage, they also give a saline laxative, make a cleansing enema. Any enveloping drink is also suitable (but this is the last thing). Be sure to call ambulance because the severity of the condition can quickly increase.

In a state of moderate and severe severity, an ambulance should be called immediately!

While the medical team is driving, lay the victim on the floor, unfasten tight clothes, turn his head to one side. Assess the presence of cardiac activity by determining the pulsation in the neck.

To recognize whether there is breath, you need to put your ear to chest. Having a stethoscope at home will make the procedure easier. If no cardiac activity is detected, it is necessary to conduct indirect massage heart and give artificial respiration.

Even during the transportation of the patient, he is injected intravenously with the Corvalol antidote - Bemegrid. It is most effective for mild intoxication.

In the hospital, the victim will be under round-the-clock medical supervision. If breathing is disturbed, connect to a ventilator ( artificial ventilation lungs), oxygen inhalation. They give a water load: they inject solutions of sodium chloride, glucose, plasma substitutes. An increase in the volume of urine output is stimulated by Eufillin and osmotic diuretics under the control of the concentration of magnesium and potassium in the blood.

In such patients, tissue nutrition is quickly disrupted, and bedsores develop, so it is very important to carry out careful care and other anti-decubitus procedures. Often this is done by relatives, not by medical staff.

With a high concentration of Phenobarbital in the blood and a stable level blood pressure undergoing hemodialysis. Severe poisoning is an indication for hemosorption with activated carbon, which in 1 session allows you to remove up to 70% of the poison.

Symptomatic treatment is mandatory.

Consequences of Corvalol poisoning

In case of Corvalol poisoning, the consequences can be very serious. Starting from severe dermatitis, ending with acute respiratory, cardiac and kidney failure. Largest number deaths among drug poisonings are observed precisely from drugs containing Phenobarbital and other long-acting derivatives of barbituric acid. The consequences are largely determined by the dose of the substance taken, the severity of intoxication, and the timeliness of therapeutic measures.

Today, in any pharmacy, you can buy Corvalol without a prescription. Due to the low availability of free medical care, it is easier for a person to drink the same Corvalol or its famous analogue Valocordin and calm down on this. It got easier and better. No wonder they say that in our clinics only the most qualified can get to the doctor. healthy man. Today, many heart patients are treated this way. Hence the transferred myocardial infarctions on the legs. Despite this for medical care should still apply. Knowing about the danger improper treatment and intoxication with Corvalol, you must take care of your health and do not take anything without consulting a specialist!

The lethal value of Corvalol is 0.1-0.3 grams per 1 kilogram of weight, or an average of 20 grams of the drug. The average lethal dose of Phenobarbital is 100 milligrams per 1 kilogram of body weight.

Chet lies article! During the night I drank current 2 fanfurics 50 ml, and 2.5 25 ml per day.

The third day I’m sausage, I just can’t move away ... I thought they would be kicked out of work, I didn’t know that there was some kind of drug there.

Sorry, it didn't work out yet, I didn't realize...

This is 20 grams of the drug per 1 kg of body weight, right?

My approximate weight is 100 kg, the physique is not fat ...

2 fanfurics 50 ml, and per day 2.5 fanfuliks 25 ml each = 162.5 ml how it doesn’t work out ... advise how to get out of this state faster ...

The article tells you what to do.

For 4 days, I took 100 ml of Corvalol daily. Now, after reading the article, I am amazed at how I survived?! I drank Corvalol, especially to sleep after a three-day drunkenness. I was afraid to just suffer a hangover.

I drink corvalol when panic attacks I've already suffered from them. It seems to help me. For 50 kg weight 20-30 drops.

Valentin, you don’t think Corvalol itself, but Corvalol along with alcohol and additives.

I drank 2 large vials from a hangover, I almost blew my head off, but the hangover let go. How to be treated?

What alcohol, what are you yelling at? Barbitura and blue is a complete tin.

I drank 6 bottles of Corvalol 30 ml each. Legs started to fail total loss orientation, talking like a drunk - the language is tangled. Falling down at every turn. I thought I had paralysis. But it takes away worse than vodka, the third day I can not move away. Guys, do not repeat the mistakes of others, it is better to buy beer or a bottle of vodka. It's better not to drink at all. And for people like us, alcohol is contraindicated.

15.02.17 daughter died at the age of 24.

In the evening, they drank beer at a friend's house, the next day her chest ached and her arms twisted at her house. The ambulance arrived and prescribed 40 drops of Corvalol, after 3-5 minutes she wheezed, foam came out of her mouth and that's it.

It is somehow related to alcohol + corvalol.

We, in the IT department, had an intelligent iron man, during the period of binges he jammed Corvalol with furiks.

They say it helps alcoholics with hangover syndrome and getting out of the binge (he was also looking for private traders on the Internet who would take him out of the binge, and he also visited the drug dealer on an outpatient basis).

Hello! My son died on December 28, 2016 ... He was dependent on Corvalol, although recent times rarely took it. But on December 25, he bought 7 bottles of Corvalol 50 mg each. We live separately and I didn't know about it. December 27 was his birthday, my husband and I stopped by to see him. He didn't look drunk. We had a bottle of champagne and a liter of light beer. And he also asked for phenazepam, because. he had panic attacks and I, in some absent-mindedness (because my mother died for 20 days), gave him 10 tablets, but he never took more than 3-4 pcs. did not accept. I drank champagne and beer, then cooked chicken in the oven and lay down to rest under the covers. But he didn't wake up again. They did an autopsy and said that he died from phenobarbital poisoning (100 mg in the stomach). But how could there be such a large dose of phenobarbital if he did not take phenobarbital pills, and he took Corvalol 5 days ago (the autopsy was done on December 30). It may or may not be. He didn't have any vomiting. He just lay down and lay down. Although at first they diagnosed acute cardiomyopathy.

For all questions, a doctor's consultation is required!

Perhaps there is no other soothing and cardiac remedy, which would be as popular as the well-known Corvalol. Even in the 21st century, many people, especially the older generation, consider it the best remedy from pain in the heart, insomnia and feelings of anxiety. Almost 100 years active use remedies in medicine should speak for its benefit, but many patients wonder whether Corvalol is harmful to health and whether its use in treatment is always justified. To answer this question, you need to consider all the positive and negative aspects of this tool.

Composition and action of the drug

Forms of release of this drug - tablets and drops. Greater popularity ever since Soviet Union Drops have always been used. Speaking about the benefits and harms of Corvalol, you need to familiarize yourself with its composition. It includes ethyl bromoisovalerianate, phenobarbital, sodium hydroxide, peppermint oil, purified water.

Corvalol in drops is a colorless liquid with a specific pungent odor. The first two ingredients in the composition of the product have a calming and antispasmodic effect, relieve excitement and nervousness, provide a strong and restful sleep. Peppermint extract dilates blood vessels, including in the heart muscle, has positive influence on intestinal peristalsis.

The components of the drug are optimally combined and complement each other's action. The use of Corvalol is indicated in the following cases:

• increased irritability, excitability, anxiety;
• insomnia against the background of emotional experiences;
• tachycardia;
• the presence of spasms in the gastrointestinal tract;
• increased blood pressure in early stages diseases.

It would seem that the benefits of the drug are undeniable, but one cannot fail to note a rather impressive list of contraindications for use.

There are frequent cases of individual intolerance to individual components of the drug. In this case, Corvalol can be dangerous to the body. Doctors do not recommend Corvalol to patients with renal and liver failure as well as under reduced pressure. In the latter case, Corvalol can bring the pressure to a critical point.

Pregnant women should be especially careful when taking the drug. Phenobarbital provokes hypoxia and irreversible damage in the central nervous system of the unborn child. Corvalol is especially dangerous in the first three months of pregnancy. Thus, its use is permissible only in extreme cases and should be under the supervision of a physician.

Harm from Corvalol can be experienced by children under 12 years of age. Its reception is possible only if the child suffers severe moral experiences and traumas. But even with such a diagnosis, taking Corvalol should not be long-term and eventually replaced by an analogue.

Of great importance when taking Corvalol is the dosage. Since the drug is perceived by many people as a harmless remedy, the number of drops may not be controlled. Before deciding whether to use Corvalol as a medicine, it is imperative to determine allowable dosage with a doctor. Otherwise, taking drops can lead to an overdose.

Overdose and side effects

To have a clear idea of ​​​​how dangerous Corvalol is, you need to know the symptoms that occur during an overdose and poisoning with this drug. dangerous dose the drug is 150 drops, but in the elderly, debilitated patients and children under the age of 12, poisoning can occur at lower doses.

There are three forms of poisoning: mild, moderate and severe intoxication. With a slight overdose, general weakness, distraction and drowsiness of the patient are noted. The patient's condition does not require any treatment and stabilizes after the end of the drug.

With moderate and severe poisoning, the patient has the following symptoms:

• muscle weakness;
• a sharp drop in blood pressure;
• dilated pupils;
• pathological sleepy state, the patient cannot be awakened;
• loss of consciousness;
• wheezing in the lungs;
• cyanosis skin faces;
• malfunctions of cardio-vascular system.

In a severe form of intoxication, coma and even death are possible.

At correct dosage drug side effects occur very rarely and are of a slightly pronounced nature. There is dizziness, general weakness, drowsiness in the daytime.

Corvalol tincture is often used as a drug to eliminate the symptoms of a hangover. Since alcohol itself causes palpitations, muscle weakness and irritability, in combination with Corvalol, these symptoms only get worse.

Also dangerous and highly undesirable simultaneous reception corvalol with tranquilizers and sedatives. double dose medicines causes backlash organism.

Habituation and dependence on Corvalol

Phenobarbital and ethyl bromisovalerianate can be considered as drugs. With regular use of Corvalol as a sedative and sedative, the patient quickly becomes addicted to the drug. You can talk about a certain degree of addiction even after two or three weeks of regular use of the remedy.

Gradually, the standard dose ceases to bring the desired effect, which leads to the need to increase the dose, which, in turn, causes health risks. In the future, the drug accumulates in the body, so even usual dose may cause phenobarbital poisoning.

It should be noted that sleep caused by a significant dose of Corvalol is often restless and does not bring a feeling of cheerfulness upon awakening.

The harm from Corvalol also lies in the development of addiction to the drug. The patient feels chronic fatigue, is in a depressed apathetic mood, speech and concentration may suffer.

Help with poisoning

If the symptoms of poisoning are insignificant, the patient needs gastric lavage. After the procedure, it is desirable to take one of the sorbents: activated carbon, smecta. Activated charcoal prevents the absorption of toxic substances into the blood and accelerates their excretion from the body. The remedy is best taken as aqueous solution. To do this, the tablet must be crushed and mixed with 100 ml boiled water room temperature. It is possible to use white activated carbon.

In case of poisoning, cleansing enemas are recommended. The victim must be provided plentiful drink, warm sweet tea is better than other drinks. It is necessary to normalize reduced pressure and replenish lost glucose stores.

With a mild degree of poisoning, these measures are usually sufficient. In case of moderate and severe poisoning, a mandatory measure should be to call an ambulance.

If the patient is in unconscious, it is placed on hard surface, loosen belts and belts, remove all jewelry that restricts movement and prevents free access of air. Before the arrival of doctors, it is necessary to monitor the state of the patient's pulse. With a severe degree of poisoning, a heart massage and an artificial respiration procedure are required.

To stabilize the condition in case of Corvalol poisoning, it is necessary intravenous administration antidote drug - bemegride. In most cases, moderate and severe forms of poisoning are treated in a hospital setting. The patient will need the help of a therapist and a gastroenterologist. Treatment in specialized institutions involves the introduction of glucose, sodium chloride, plasma and diuretics. With a significant concentration of phenobarbital in the blood, hemodialysis may be necessary.

Consequences of corvalol poisoning

Severe poisoning can have further complications for the body. Subsequently, there may be allergic reactions on the skin in the form of rashes, burning and itching. Also, pathologies of the liver and kidneys, disturbances in the work of the central nervous system, a high risk of heart attack and stroke are not uncommon.

Severe poisoning in a child can even be fatal.

The benefits and harms of Corvalol should be considered when choosing a dosage. At neurological diseases the number of drops should not exceed 15-20, in case of nervous conditions - 10-15, to relieve pain in the heart - up to 40 drops. The number of doses should not exceed 3 times a day.

Careful adherence to the dosage of the drug, prior consultation with the doctor, careful use of the drug will contribute to effective action corvalol without negative consequences for the body.

Corvalol with a release form - tablets and drops has a sedative, antiseptic, choleretic, vasodilating effect. As part of the active ingredient - phenobarbital, irritating effect on the cold receptors of the mucous membrane oral cavity and gastrointestinal tract, dilates the vessels of the heart and brain, eliminates signs of flatulence, enhances intestinal motility.

Like any medicine, Corvalol has side effects, despite the release in pharmacies without a doctor's prescription. Before using the tincture, it is important to read the instructions, take into account the indications, contraindications and side effects. It is best to consult with your doctor first.

Side effects of Corvalol

In the composition (drops, tablets) Corvalol - phenobarbital, which forms mental addiction if taken continuously and in high doses. In particular, active ingredient- bromine, leading in case of overdose to:

• confusion of consciousness;
• impaired coordination of movements;
• tendency to depression, panic attacks;
• inhibition of the function of the central nervous system;
• dizziness;
• drowsiness;
• bradycardia;
• nausea, vomiting;
• pain in the stomach;
• slowing down the heart rate;
• allergies, skin rashes;
• stool disorder.

It is phenobarbital that is addictive against the background of constant, long-term use, so the effect as a sleeping pill will gradually decrease. But the withdrawal syndrome in the event of a sharp cessation of taking the drug may well lead to overexcitation, hallucinations, and excessive anxiety.

Long-term treatment with Corvalol leads not only to dependence, but also to the accumulation of metabolites in the body, the development of hypotension, and pulse disturbance, when in severe cases it is no longer possible to do without resuscitation and disinfection intoxication therapy.

REFERENCE! Corvalol can dramatically lower blood pressure, which is dangerous for hypertensive patients suffering from high rates HELL. It is not recommended to take the medicine in conjunction with other antiarrhythmic, hypotensive, anticonvulsant, steroid drugs. The effect may be unexpected and unfavorable.

Corvalol is incompatible with alcohol, which will lead to toxic effects on the body, the accumulation of ethanol in the blood, and side effects.

Side effects in children

According to the instructions, it is forbidden to use the drug for children under 18 years of age. Only in extreme cases is it possible for the attending physician to prescribe, taking into account the weight and age of the child, no more than 15 drops 1 time per day. Wherein healing process should be carried out under full control in order to avoid the negative impact of the alcohol-containing composition on the child's fragile body.

It is forbidden to take Corvalol for pregnant women during lactation. The active ingredient can have a teratogenic effect on the fetus, lead to infants at birth congenital anomalies in the building internal organs, deformity of anatomical structures.

The medicine can provide Negative influence on the development of the child, lead to the suppression of the nervous system. In infants in the first days of life - provoke increased bleeding.

If a pregnant mother abuses this drug in the 3rd trimester, then convulsions and excessive excitability in infants in the first weeks of life may occur. Women in an interesting position, in order to calm the nerves, are not recommended to take Corvalol and it is better to give preference to other, safer and more effective sedatives.

The main side effects in a child:

• excessive excitability;
• convulsions;
• bleeding;
• deterioration of blood clotting due to suppression of the nervous system by phenobarbital.

Indications for use

Corvalol - vasodilator, sedative, sedative. However, it cannot be considered a medicine, because it is impossible to cure any internal disease with only one drug. Corvalol helps to minimize nervous disorders but won't get rid of renal colic, insomnia, heart disease (myocardial infarction, angina pectoris). These are cheap drops indicated for use to minimize unpleasant symptoms or aid in addition to the main treatment. Main indications for use:

• increased heart rate;
• signs of tachycardia;
• insomnia;
• spasms of the coronary vessels;
• irritability;
• hypertension at the initial stage;
• vegetovascular dystonia for the purpose of complex therapy;
• spasms in the intestines.

The drug will help you quickly calm down and fall asleep, while not getting rid of severe neurosis, progressive depression.

IMPORTANT! Corvalol is not a cure for heart disease and will not help hypertensive patients to normalize blood pressure. The remedy can only have a temporary effect when it appears discomfort in the region of the heart. This medicine is not prescribed as a drug in the treatment of diseases, therefore, it is not recommended to abuse dosages and frequency of use.

Contraindications to the use of Corvalol

The drug is contraindicated if there is:

• low blood pressure;
• heart failure;
• heart disease;
• dysfunction of the kidneys, liver;
• individual intolerance;
• allergy to lactose;
• epilepsy;
• traumatic brain injury;
• convulsive syndrome;
• alcohol addiction;
• diabetes.

It is not advisable to take medicine for children under 18 years of age and pregnant women in the 1st trimester up to 12-14 weeks and for later dates. Also during lactation.

IMPORTANT! In heart failure, the medicine can cause myocardial infarction, so it is better for hypertensive patients to choose other drugs for treatment on the advice of a doctor.

Actions in case of overdose

If, after all, it was not possible to avoid an overdose of Corvalol, then it is important to be able to provide first aid in a timely manner and eliminate signs of intoxication, remove toxic substances from the body. This means that you need to rinse your stomach, drink 2-3 glasses of pure water, take a sorbent (Smecta, Enterosgel, Filtrum, activated carbon). You can press on the root of the tongue, thereby causing a gag reflex.

The main thing is to quickly remove excess Corvalol from the body. In case of occurrence lethargic sleep, coma, convulsions, you need to call an ambulance immediately.

Doctors consider cases of overdose of mild, moderate, severe. If there are mild signs of poisoning: drowsiness, absent-mindedness, dizziness, apathy, headache and lethargy, it is important to stop taking the drug in time. If the patient continues to take Corvalol in increased doses, then the state may go into middle degree severity with the appearance of spasm in the muscles, convulsions, vascular collapse. In the event of the transition of poisoning to a severe stage, the patient may fall into a coma when the threat looms lethal outcome and if not provided in a timely manner emergency assistance, then everything can end badly.

Corvalol has long been not just a drug, but an element of the subculture for the elderly, which is the same integral attribute of their life as a cup of tea to their favorite TV series.

His moderate sedative effect allows the use of the drug as a sedative for sleep disturbances, increased irritability and neuroses, and the vasodilating effect contributes to the correction of functional abnormalities of the cardiovascular system

On this page you will find all information about Corvalol: complete instructions on application to this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Corvalol. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug with a sedative and antispasmodic effect.

Terms of dispensing from pharmacies

Released without a doctor's prescription.

Prices

How much does Corvalol cost? The average price in pharmacies is at the level of 30 rubles for drops and 130 rubles for tablets.

Release form and composition

The following dosage forms of Corvalol are produced:

• Drops (in dark glass dropper bottles of 10, 15, 25, 30 or 50 ml, jars of 100 ml; in a cardboard pack of 1 bottle or jar);
• Tablets - flat, round, beveled to the edge, white or almost white, interspersed (in blister packs of 10 pcs; in a carton pack of 2, 10, 30, 50 or 100 packs).

Composition of 1 tablet:

• Active ingredients: peppermint oil - 0.58 mg, ethyl ester of α-bromoisovaleric acid - 8.2 mg, phenobarbital - 7.5 mg;
• Auxiliary components: microcrystalline cellulose - 10.5 mg, magnesium stearate - 0.9 mg, beta-cyclodextrin - 55.55 mg, lactose monohydrate - 43.77 mg, potato starch - 13 mg.

Composition of 1 ml drops:

• Active ingredients: phenobarbital - 18.26 mg, ethyl ester of α-bromoisovaleric acid - 20 mg;
• Auxiliary components: peppermint oil, ethanol 95%, purified water, sodium hydroxide.

Pharmacological effect

Corvalol is a sedative and antispasmodic drug, the action of which is determined by the components present in it.

1. Phenobarbital. The active phenobarbital is a sedative component that inhibits the propagation of nerve impulses to the neurons of the cerebral cortex. Thanks to this substance, a feeling of lethargy appears with a pronounced decrease in the speed of reactions. The compound calms the nervous system, inducing sleep. Useful for hyperactive individuals.
2. Peppermint oil. This substance is rich in menthol esters. When it is taken in a person, vasodilation is noted and intestinal contractility increases. Peppermint oil is an excellent antispasmodic for many internal structures. Corvalol has a mint flavor, which contributes to the creation of an antiseptic effect in the oral cavity.
3. Ethyl ester of "a-bromizovaleric acid". The contained alcohol acts on the sensitive endings located in the pharynx and oral cavity, reducing the level of excitability of the nervous apparatus. This creates a characteristic inhibition with the development of a sedative and antispasmodic effect. Taking large doses of the drug leads to the formation of a hypnotic effect.

Corvalol reduces the excitatory effect on the vasomotor centers, peripheral and coronary vessels, lowering the total blood pressure, thereby relieving and preventing vasospasm, especially the heart.

Indications for use

as a sedative and vasodilator Corvalol is prescribed for the following diseases:

• vegetative lability;
• in sleepless conditions, especially in violation of falling asleep;
• neurotic states, irritability, hypochondriacal syndrome;
• disorders of the functions of the cardiovascular system (sinus, cardialgia, various disorders of blood pressure).
• as an antispasmodic, Corvalol is indicated for spasms of the muscles of the organs gastrointestinal tract such as intestinal or biliary colic.

What is the danger of Corvalol?

1. it popular remedy in the countries of the former USSR, but banned in Poland, Germany, USA, Norway, Lithuania. Prohibitive measures were taken due to the presence of the psychoactive compound phenobarbital in the composition of Corvalol, as well as the toxic bromine-containing component.
2. It is phenobarbital that causes a quick and strong addiction - in some cases, 2-3 weeks of taking the drug is enough for the development of drug dependence. Moreover, phenobarbital causes not only physical, but also psychological dependence.
3. After the abolition of Corvalol, people develop the so-called "withdrawal" syndrome - a depressed state, the patient complains of constant nausea, intense headaches.

However, the drug has one important advantage - it has the fastest and most powerful effect. If taken in small doses and extremely moderately, then Corvalol can quickly, almost instantly, relieve anxiety. In general, the recommended doses of the remedy are not dangerous, but the problem is that if you take it constantly, then there is a need to increase the dosage. The most dangerous thing is that these doses do not just increase each time, but lead to real pleasure: depression and dizziness are replaced by euphoria immediately after taking the right dose.

Contraindications

For both dosage forms:

1. Lactation period (or stop breastfeeding);
2. Severe hepatic/renal failure;
3. Hypersensitivity to components.

Tablets are also contraindicated in the following cases:

1. Pregnancy;
2. Lactose intolerance, lactase deficiency, glucose-galactose malabsorption (due to lactose content);
3. Age up to 18 years (experience with the drug in this dosage form not present in this age group).

With extreme caution, Corvalol in the form of drops can be prescribed during pregnancy.

Use during pregnancy and lactation

Corvalol during pregnancy is contraindicated, since phenobarbital can very adversely affect the development of the baby.

Phenobarbital has a depressing effect on the nervous system of both mother and child, worsens blood clotting, causing bleeding in the first days of life in a newborn. Abuse of Corvalol in the third trimester of gestation causes addiction and subsequent withdrawal syndrome, which can be traced in the child in the development of seizures and severe excitability after childbirth or in the first two weeks of life.

The use of the drug for breastfeeding also contraindicated.

Instructions for use

The instructions for use indicate that Corvalol drops are taken orally before meals.

• How much does an adult need? Usually it is 15-30 drops, they must first be dissolved in a small amount (30-50 ml) of water, 2-3 times / day. A single dose, if necessary (for example, with tachycardia), can be increased to 40-50 drops.
• Children - 3-15 drops / day (depending on age and clinical picture diseases).

Instructions for tablets

The dose is set individually. Take orally, before meals, drink water. Adults are usually prescribed 1-2 tablets 2 times a day. With tachycardia single dose may be increased to 3 tablets. Maximum daily dose is 6 tablets.

The duration of the drug is set by the doctor individually.

Side effects

Subject to the dosages indicated in the instructions, Corvalol drops are well tolerated by patients. In some cases, individuals with increased individual sensitivity may develop the following adverse reactions:

1. Tremor of the limbs;
2. nausea, vomiting, bloating;
3. Dizziness, weakness, drowsiness, lethargy, lethargy;
4. Slowing the frequency of heart beats per minute, lowering blood pressure.

As a rule, all these phenomena quickly disappear on their own after discontinuation of therapy.

Overdose

Overdose is possible in the case of frequent and prolonged use of the drug, which is associated with the process of cumulation of its components. Quite long and permanent application can cause addiction, psychomotor agitation and withdrawal syndrome. A sharp refusal to take Corvalol can provoke a withdrawal syndrome.

Symptoms of an overdose include:

• depression of the central nervous system;
• confused mind;
• dizziness;
• drowsiness;
• ataxia;
• falling asleep.

In especially severe cases of drug poisoning, respiratory failure, tachycardia, arrhythmia, lowering blood pressure, collapse and coma are possible.

An overdose of Corvalol is treated with symptomatic therapy. With depression of the nervous system, nikethamide, caffeine are indicated.

special instructions

There is no experience of using the drug in children under 18 years of age.

During the use of the drug should not drink alcohol.

drug interaction

Drugs that depress the central nervous system enhance the effect of the drug.

The action of the drug is enhanced by the use of valproic acid preparations.

Phenobarbital (an inducer of microsomal oxidation) may reduce the effectiveness of drugs metabolized in the liver (including derivatives of coumarin, griseofulvin, glucocorticosteroids, oral contraceptives); enhances the action of local anesthetics, analgesics and sleeping pills. The drug enhances the toxicity of methotrexate.