Melaxen analogues and prices. Melaxen® - detailed instructions for use, price, reviews, analogues How to find a cheap analogue of an expensive medicine

This page provides a list of all Melaxen analogues by composition and indication for use. A list of cheap analogues, and you can also compare prices in pharmacies.

Most cheap analogue Melaxen:
The most popular analogue of Melaxen:
ATX classification: Melatonin
Active ingredients/composition: melatonin

Cheap analogs of Melaxen

When calculating the cost cheap analogs of Melaxen the minimum price was taken into account, which was found in the price lists provided by pharmacies

Popular analogs of Melaxen

The list of drug analogues based on statistics of the most requested drugs

All analogues of Melaxen

The above list of drug analogues, which indicates Melaxen substitutes, is the most suitable because they have the same composition of active ingredients and coincide in indications for use

Different composition, may have the same indication and method of use

Name	Price in Russia	Price in Ukraine
motherwort extract, magnesium, vitamin B6	173 RUR	1200 UAH
	112 rub.	16 UAH
Peppermint, Phenobarbital, Ethyl Bromoisovalerianate	--	1 UAH
diazepam, cyclobarbital	--	--
validol, phenobarbital, ethyl bromizovalerianate	72 rub.	11 UAH
Peppermint, Phenobarbital, Hops, Ethyl Bromoisovalerianate	69 RUR	10 UAH
peppermint, phenobarbital, ethyl bromizovalerianate	12 rub.	6 UAH
phenobarbital, ethyl bromoisovalerate	--	11 UAH
phenobarbital, ethyl bromoisovalerate	--	11 UAH
	--	--
α-bromoisovaleric acid ethyl ester, phenobarbital	--	--
Levana	--	27 UAH
zopiclone	304 rub.	134 UAH
zopiclone	164 RUR	--
zopiclone	--	25 UAH
zopiclone	560 rub.	14 UAH
zopiclone	--	--
zopiclone	--	17 UAH
zopiclone	--	--
zopiclone	--	29 UAH
zopiclone	--	--
zopiclone	--	--
zopiclone	--	--
	--	--
zaleplon	--	37 UAH
Belladonna, Valerian officinalis, Lily of the valley, menthol, sodium bromide	--	2 UAH
valerian officinalis, rutoside, hops	--	28 UAH
Peony evasive	11 rub.	3 UAH
	--	26 UAH
Oregano, Linden, Melissa officinalis, Passionflower, Salvia officinalis	--	--
hawthorn, valerian officinalis, lemon balm, motherwort	1570 rub.	38 UAH
Hawthorn, Valerian officinalis, Oregano, Stinging nettle, Melissa officinalis, Motherwort, Oregano, Hops	--	--
Hawthorn, Elderberry, Valerian officinalis, Guaifenesin, St. John's wort, Melissa officinalis, Passionflower, Hops	--	48 UAH
Belladonna, Hawthorn, Oregano, Stinging nettle, Motherwort, Hops, Salvia officinalis	--	29 UAH
	123 RUR	225 UAH
Melissa officinalis	29 RUR	6 UAH
Valerian officinalis, Passionflower	--	75 UAH
Motherwort	9 RUR	2 UAH
Hawthorn, Valerian officinalis, Peppermint, Yarrow, Hops	--	--
Valerian officinalis, St. John's wort, Melissa officinalis	990 rub.	49 UAH
	--	39 UAH
	--	24 UAH
Passionflower	--	17 UAH
	--	--
doxylamine	--	21 UAH
	23 rub.	7 UAH
Valerian officinalis, Peppermint, Motherwort, Licorice glabra, Hops	75 RUR	7 UAH
Valerian officinalis, Peppermint, Motherwort, Licorice glabra, Hops	--	13 UAH
Valerian officinalis, Sweet clover, Oregano, Motherwort, Common thyme	46 RUR	21 UAH
Sweet clover, Calendula officinalis, Coriander, Milk thistle, Licorice glabra	--	19 UAH
Valerian officinalis, Peppermint, Motherwort, Licorice glabra, Hops	--	43 UAH
Baikal skullcap	--	9 UAH
	--	145 UAH
combination of many active ingredients	--	94 UAH
valerian, lemon balm, peppermint	--	--
hawthorn fruits, lemon balm medicinal herb, motherwort herb, rosehip fruit, Echinacea purpurea herb	94 RUR	250 UAH
extractant	--	36 UAH
Valerian officinalis	80 rub	9 UAH
Valerian officinalis	--	12 UAH
Valerian officinalis	--	--
	332 rub.	648 UAH
Valerian officinalis	2 rubles	2 UAH
Valerian officinalis	36 rub.	7 UAH
Valerian officinalis	2 rubles	1 UAH
	--	310 UAH
valerian extract	--	77 UAH
valerian	--	419 UAH
bromocamphor	126 rub.	10 UAH
	25 rub.	3 UAH
dexmedetomidine	8000 rub	2115 UAH
thick adonis herb extract, potassium bromide	34 rub.	14 UAH
Dry passionflower extract	1680 rub.	43 UAH
St. John's wort	--	35 UAH
	465 RUR	63 UAH
Valerian officinalis, Melissa officinalis	206 RUR	52 UAH
	--	40 UAH
validol, peppermint, hops, ethyl bromizovalerianate	--	7 UAH
Valerian officinalis, Peppermint	--	23 UAH
St. John's wort	487 RUR	124 UAH
hawthorn, black elderberry, valerian officinalis, guaifenesin, St. John's wort, lemon balm Passiflora, Hops	161 RUR	36 UAH
homeopathic potencies of various substances	180 rub.	24 UAH
Valerian officinalis, Melissa officinalis, Peppermint	128 rub.	32 UAH
Hawthorn, Passionflower	--	63 UAH
Valerian officinalis, Melissa officinalis, Peppermint	2856 RUR	32 UAH
Valerian officinalis, Melissa officinalis, Peppermint	--	29 UAH
hawthorn, valerian officinalis, St. John's wort, peppermint, nicotinamide, pyridoxine, hops	--	30 UAH
Valerian officinalis, Melissa officinalis, Peppermint	--	40 UAH
homeopathic potencies of various substances	--	44 UAH
Hawthorn, Valerian officinalis, Motherwort	--	21 UAH
doxylamine	--	16 UAH
doxylamine	--	17 UAH
Valerian officinalis, Trefolia trifolium, Peppermint, Hops	--	31 UAH
	--	23 UAH
homeopathic potencies of various substances	--	154 UAH
homeopathic potencies of various substances	--	91 UAH
homeopathic potencies of various substances	48 RUR	17 UAH
Hawthorn, Sweet clover, Coriander, Melissa officinalis, Oats, Motherwort, Hops	--	13 UAH
passionflower extract, doxylamine	--	2 UAH

To compile a list of cheap analogues of expensive drugs, we use prices that are provided to us by more than 10,000 pharmacies throughout Russia. The database of drugs and their analogues is updated daily, so the information provided on our website is always up to date as of the current day. If you have not found the analogue you are interested in, please use the search above and select the medicine you are interested in from the list. On the page of each of them you will find everything possible options analogues of the sought-after medicine, as well as prices and addresses of pharmacies where it is available.

How to find a cheap analogue of an expensive medicine?

To find inexpensive analogue medicine, generic or synonym, first of all we recommend paying attention to the composition, namely the same active ingredients and indications for use. The same active ingredients of a drug will indicate that the drug is a synonym for the drug, pharmaceutically equivalent or a pharmaceutical alternative. However, we should not forget about the inactive components of similar drugs, which may affect safety and effectiveness. Do not forget about the instructions of doctors; self-medication can harm your health, so before consuming any medical product Always consult your doctor.

Melaxen price

On the websites below you can find prices for Melaxen and find out about availability at a pharmacy near you

Melaxen instructions

Instructions
By medical use drug
Melaxen

Compound:

Melaxen (Melatonin, 3 mg) - medicine to normalize the daily sleep-wake cycle and regulate biological rhythms.

Description:
round, biconvex, film-coated tablets ranging from white to yellowish in color, with a scored line on one side of the tablet.

Pharmacotherapeutic group:
Adaptogenic agent.

ATX code: N05CM17

Melaxen is a chemical analogue of the biogenic amine Melatonin. Chemical formula N-acetyl-5-methoxytryptamine. Molecular weight 232. Dissolves in water, alcohol, lipids. Penetrates well through the blood-brain barrier. Synthesized from amino acids of plant origin.

Pharmacological properties:

Is synthetic analogue pineal gland hormone. Normalizes circadian rhythms. Regulates the sleep-wake cycle, daily changes in locomotive activity and body temperature. Helps normalize night sleep (accelerates falling asleep, reduces the number of night awakenings, improves well-being after waking up in the morning, does not cause a feeling of lethargy, weakness and fatigue upon awakening, dreams become more vivid and emotionally rich).

Indications

As a sleeping pill.

As an adaptogen to normalize biological rhythms.

Contraindications

Hypersensitivity, severe renal dysfunction, autoimmune diseases, leukemia, lymphoma. Allergic reactions, lymphogranulomatosis, myeloma, epilepsy, diabetes, chronic renal failure, pregnancy and lactation.

Directions for use and doses

Inside. Adults take ½-1 tablet 30-40 minutes before bedtime once a day. As an adaptogen when changing time zones: 1 day before the flight and in the next 2-5 days, 1 tablet 30-40 minutes before bedtime. Maximum daily dose up to 2 tablets per day.

Best before date

4 years. Do not use after expiration date.

Release from pharmacies

Without a doctor's prescription.

All information is presented for informational purposes and is not a reason for independent prescription or replacement of medication.

A healthy adult needs 7 to 9 hours of sleep a night. According to statistics, people with sleep disorders and insomnia are more likely to get into traffic accidents, miss work, and are generally less satisfied with life and their social status. Studies have shown that the risk of strokes, hypertension, atherosclerosis, obesity, diabetes and depression is significantly higher in patients suffering from insomnia. What should those who sleep poorly do? Melatonin tablets can help with this.

Briefly about melatonin

This is a hormone secreted by the pineal gland. Because it takes part in the regulation of daily biorhythms, it is also called the “sleep hormone.” However, the range of responsibilities of this hormone is much wider. He is involved in:

regulation of ovulation cycles and the onset of menopause in women,
antioxidant protection body,
immunomodulation,

thermoregulation,
regulation of blood pressure,
regulation lipid metabolism,
processes of memory and aging.

The pineal gland is located in the deep structures of the brain. This organ is surrounded by a mystical halo; some consider it the “third eye.” There is some truth in this, since it reacts directly to light. From the retina to optic nerve the light signal is transmitted to the hypothalamus, from where nerve pathways brain stem and sympathetic nerves enter the pineal gland.

The relationship between the light signal and the production of this normon is inverse. There is light - no output. As soon as retinal stimulation decreases, sympathetic nerves begin to secrete norepinephrine, which causes the secretion of melatonin into the blood.

The production of this substance in dark time days increases by 25–30 times. People with sleep disorders tend to have low levels of the hormone, so melatonin-based medications are a logical solution to insomnia.

4 popular drugs with melatonin

It is believed that more than 50% of the population experiences occasional sleep problems, especially in old age. A chronic sleep disorder called insomnia (insomnia) affects about 10-20% of people. Melatonin medications became popular for its treatment in the mid-1990s. It has been found that taking them reduces the time required to fall asleep and reduces the number of night awakenings.

Let's look at three products that you can most often be offered at a pharmacy: Melaxen, Melarena and Circadin.

Melaxen - an imported product

Melaxen contains 3 mg melatonin. It is produced by Unipharm (USA) in the form of tablets of 12 or 24 pcs. The instructions specifically indicate that the drug can be used when changing time zones to improve adaptation and prevent desynchronosis. This happens when people fly and “jump” across 8–10 time zones at once. In such cases, the so-called “jet lag” or jet lag syndrome may occur, so it is recommended to take it 1 day before travel and in the next 5 days.

Interesting fact established while monitoring passengers on long-haul flights. It turned out that melatonin significantly reduced jet lag when taken on eastbound flights, but was less effective on westbound flights. Another study found that the hormone was only effective when taken one day before a flight.

Updated. Current pricing makes Melaxen for 12 tablets absolutely unprofitable for the consumer due to the very small (20-50 rubles) difference in price compared to a package of 24 tablets (see table below).

Melarena - Russian analogue of Melaxen

It is produced by Makis-Pharma in the form of tablets with the following dosage:

0.3 mg each,
3 mg each.

According to the instructions, the main indications for taking tablets in a smaller (0.3 mg) dosage are:

weather sensitivity,
fatigue,
desynchronosis.

For cases requiring higher concentrations (3 mg) for:

sleep-wake cycle disorder,
desynchronosis caused by flying or working night shifts,
use tablets with higher dose hormone.

Circadin is a long-acting drug

Positioned as a melatonin-containing analogue of Melarena and Melaxen, which has a prolonged effect. It contains 2 mg of active substance in a special form. Manufacturer: SwissCo Servises (Switzerland) or Catalent Germany Schorndorf (Germany) for RAD Neurim Pharmaceuticals EEC (UK).

The “highlight” is that its action corresponds to the physiological profile of melatonin secretion in the body. What is known about this drug is that it was specifically designed to treat insomnia in patients aged 55 years and above. Complaints about poor sleep quality at this age are increasing, so it was necessary to create a drug that combines therapeutic efficacy and safety. This task is not so simple.

The fact is that if you take a hormone from the outside, it is quickly absorbed and absorbed by the body. After 0.5–2 hours, its dose is sharply reduced. For example, for Melaxen, the half-life is 0.5–1 hour. Maintaining physiological concentrations sufficient for good night, requires either repeated administration or gradual release from medicinal product. In the first case, the risk of overdose, addiction to the drug and deterioration in liver function, which metabolizes melatonin, increases.

The hormone is released slowly from Circadin in the intestines, thereby imitating the physiological patterns of secretion. Its maximum concentrations in the blood appear 2.6 hours after administration and persist for 3.5 hours before decreasing, covering the entire night period. At the same time, the dosage of melatonin in Circadin is 1 mg less than in Melaxen, and the effect is prolonged.

synchronize the level of exogenous melatonin with natural biorhythms;
ensure full coverage of nighttime sleep with the drug.

Placebo-controlled clinical trials Circadin has been shown to improve sleep induction, with effects comparable to some sleeping pills. However, unlike them, the drug did not affect cognitive and psychomotor skills, did not cause dependence or side effects.

Melatonin SZ is still an inexpensive domestic analogue

A relatively cheap drug compared to imported ones from the Russian company Severnaya Zvezda, which specializes in the production of . A package of 30 tablets of 3 mg will cost approximately the same as Melaren, about 300 rubles. The quality of domestic generics is usually approximately the same, since raw materials are most often purchased from the same Chinese suppliers, only Melaren is produced in Moscow, Melatonin-SZ in the Leningrad region. When choosing between them, you can only be guided by subjective feelings; almost all reviews on the Internet are fake.

Rescue from insomnia or placebo?

Numerous Scientific research confirm that sleep tablets with melatonin work well in people with a primary sleep disorder. A 2013 meta-analysis of 1,683 patients with insomnia demonstrated a decrease in time to fall asleep and an increase in total sleep time and quality of sleep in patients taking the hormone compared to placebo.

However, there is also contrary data. A placebo-controlled study conducted in 2003 in Canada showed that sleep efficiency and total sleep time in patients previously taking benzodiazepines (sleeping pills) were not statistically significantly different between melatonin groups at two dosages (0.3 and 3 mg) and placebo. Possibly after systematic use sleeping pills the effect of melatonin drugs is reduced.

Caution: hormone!

Don't forget that any hormonal agents should be taken with caution. Recommendations for taking medications should be given by a doctor. Melatonin-containing products are usually not used on a regular basis, as their long-term use leads to hormonal imbalances.

Melatonin affects the levels of gonadotropic and sex hormones. Among women high level this substance may have a contraceptive effect. In men, while taking it, the number of sperm and their motility may decrease. Both men and women may experience decreased libido.

The drugs may cause drowsiness during the day, so caution should be exercised when driving and in hazardous areas. This side effect can be corrected by reducing the dosage.

An overdose can cause mood swings, dizziness, and depression. Therefore, it is absolutely necessary for patients prone to such reactions to take the medicine only under the supervision of a doctor.

People suffering from hypotension, atherosclerosis and diabetes also need to be careful. The substance affects cholesterol levels and can reduce arterial pressure, increase blood glucose levels and reduce insulin sensitivity.

General contraindications for use: pregnancy and breastfeeding, hypersensitivity, diabetes mellitus, epilepsy, allergies, autoimmune diseases, lymphoma, lymphogranulomatosis, myeloma, leukemia, severe renal failure.

Cost of drugs

A package of Melaxen (24 tablets) costs about 650 rubles. The packaging of domestic drugs Melaren or Melatonin-SZ contains a larger number of tablets (30 tablets), but its price is approximately 2.5 times less. Long-acting circadin is packaged in packages of 21 tablets and is the most expensive representative in terms of 1 piece.

The page contains instructions for use Melaxena. It is available in various dosage forms drug (3 mg tablets, Balance), and also has a number of analogues. This abstract has been verified by experts. Leave your feedback on the use of Melaxen, which will help other site visitors. The drug is used for various diseases(disturbance in falling asleep, insomnia, desynchronosis). The product has a number of side effects and interactions with other substances. Doses of the drug differ for adults and children. There are restrictions on the use of the medicine during pregnancy and breastfeeding. Treatment with Melaxen can only be prescribed by a qualified physician. The duration of therapy may vary and depends on the specific disease. Composition of a sleeping pill.

Instructions for use and dosage

Adults are prescribed 1/2-1 tablet 1 time per day 30-40 minutes before bedtime.

When used as an adaptogen when changing time zones 1 day before a flight and in the next 2-5 days - 1 tablet 30-40 minutes before bedtime. The maximum daily dose is up to 2 tablets per day.

Release forms

Film-coated tablets 3 mg (Balance).

Compound

Melatonin + excipients.

Melaxen- an adaptogenic drug, a chemical analogue of the biogenic amine melatonin. Synthesized from amino acids of plant origin.

It is a synthetic analogue of the pineal gland hormone. Normalizes circadian rhythms. Regulates the sleep-wake cycle, daily changes in physical activity and body temperature. Helps normalize night sleep: accelerates falling asleep, improves sleep quality, reduces the number of night awakenings, improves well-being after waking up in the morning, does not cause a feeling of lethargy, weakness and fatigue upon awakening, dreams become more vivid and emotionally rich.

Adapts the body to rapid changes in time zones, reduces stress reactions. Shows immunostimulating and pronounced antioxidant properties.

Inhibits the secretion of gonadotropins and, to a lesser extent, other hormones of the adenohypophysis (corticotropin, thyrotropin and somatotropin). Does not cause addiction or dependence.

Pharmacokinetics

When taken orally, it is quickly and completely absorbed and easily passes histohematic barriers, including the blood-brain barrier (BBB).

Indications

as a sleeping pill;
as an adaptogen to normalize biological rhythms;
desynchronosis.

Contraindications

severe renal dysfunction;
autoimmune diseases;
leukemia;
lymphoma;
allergic reactions;
lymphogranulomatosis;
myeloma;
epilepsy;
diabetes;
chronic renal failure;
pregnancy;
lactation period (breastfeeding);
hypersensitivity to the components of the drug.

special instructions

It is necessary to inform women who want to become pregnant that the drug has a weak contraceptive effect.

During the period of use of the drug, you should avoid exposure to bright light.

Impact on the ability to drive vehicles and operate machinery

During the treatment period, it is necessary to refrain from driving vehicles and other potentially dangerous activities. dangerous species activities that require increased concentration and speed of psychomotor reactions.

Side effect

headache;
morning drowsiness;
nausea, vomiting;
diarrhea;
allergic reactions to the components of the drug;
swelling in the first week of use.

Drug interactions

At simultaneous use Melaxen enhances the effect of drugs that have a depressant effect on the central nervous system and beta-blockers.

Incompatible with MAO inhibitors, glucocorticosteroids (GCS) and cyclosporine.

Analogues of the drug Melaxen

Structural analogues of the active substance:

Melaxen Balance;
Circadin.

Analogues pharmacological group(sleeping pills):

Andante;
Apo Flurazepam;
Berlidorm 5;
Bromized;
Heminevrine;
Hypnogen;
Donormil;
Dormicum;
Zaleplon;
Zolpidem;
Zolsana;
Zopiclone;
Ivadal;
Imovan;
Nitrazadone;
Nitrazepam;
Nitram;
Nitrest;
Nitrosan;
Piklodorm;
Reladorm;
Relaxon;
Reslip;
Rohypnol;
Sanwal;
Signopam;
Snovitel;
Somnol;
Thorson;
Phenobarbital;
Flormidal;
Estazolam;
Eunoctine.

Use during pregnancy and breastfeeding

The drug Melaxen is contraindicated for use during pregnancy and lactation (breastfeeding).

There are few things worse than insomnia, the inability to get enough sleep, frequent awakenings in the middle of the night, and in the morning you have to go to work. Insomnia affects both the body and soul of a person, and to a large extent, the ability to function every day. In such cases, many people resort to sleeping pills to finally get some sleep. But not all sleeping pills are equally useful - and not all drugs have only positive effects on people.

When to look for a replacement

Melatonin is one of the most potent remedies for insomnia. The human body itself produces it to regulate sleep. Melatonin is produced by the pituitary gland, released at night in accordance with the rhythm of sleep, and then dissipates as soon as the morning light dawns and it is time to wake up.

Of the many functions of melatonin, the role best understood is the role it plays in maintaining circadian rhythms. In humans, circadian rhythms or "clocks" are regulated by an area called the suprachiasmatic nucleus.

Using the daily cycle of light and dark, this area creates and maintains a daily cycle.
Certain hormones are released at certain times of the day. Late evening and early evening release hormones that prepare the body for sleep. In the early hours of the morning, the body begins to prepare for wakefulness and activity.
Information about light levels reaches the suprachiasmatic nucleus and is then transmitted to the pineal gland deep in the center of the brain.
The pineal gland releases melatonin at night and suppresses its release during daylight.
Even when a person is kept away from all external sources of light and time, the body maintains a natural rhythm of wakefulness and sleep.

Melatonin is also a powerful antioxidant, has an anti-inflammatory effect and plays a important role for functioning immune system. Melatonin receptors are present in the brain, cardiovascular system, liver, intestines and kidneys. It is difficult to overestimate the role that melatonin plays for the body. Cheap analogues, although they allow a person to fall asleep, do not have the full spectrum useful properties, which are inherent in melatonin.

Production of melatonin, a circadian rhythm hormone, for human body absolutely natural process. However, some events, such as stress, bad conditions for sleep, airplane flights to a different time zone and other factors may temporarily affect its production. If this happens, external melatonin can be added in medication form to help the body cope. However, if you take melatonin long time, the body's natural production of this substance decreases. As a result, addiction can form.

However, you can stop taking melatonin - cheap analogues in some cases can be no less effective for normalizing sleep. If you are already accustomed to using melatonin, you can gradually reduce the dose until the time comes to quit the drug completely.

It is also worth looking for a melatonin analogue if there is an individual intolerance to the drug or its components, or side effects when taking the medicine are such that its further use is undesirable.

Side effects from taking melatonin may include:

headache;
dizziness;
nausea;
pressure surges;
irritability;
and, oddly enough, sleep disturbances.

Melatonin may interact negatively with other medications, such as immunosuppressants, blood thinners, diabetes medications, and birth control pills. In such cases, you should also think about possible alternatives to medications that contain melatonin. Substitutes may lack some or all of the side effects of melatonin, depending on how your body reacts to them.

Cheap replacement options

There are a huge number of simple measures for sleep that are more effective than medications.

Mask for sleep. The simplest, but surprisingly effective solution. The mask protects the eyes from the slightest exposure to light, helping the body relax and increase the production of its own “sleep hormone” - melatonin - without any chemical additives.
Herbal teas . For centuries, herbal infusions have been used to treat wide range physical and psychological illnesses, including anxiety, depression and insomnia. Teas with valerian, lemon balm, motherwort tincture, and sedative fees, which are sold without a prescription at any pharmacy. It is important that these teas also taste good. They stimulate the body to produce its own melatonin.
Magnesium-containing preparations. The body needs magnesium for muscle relaxation, proper alternation of sleep phases and stable functioning. nervous system. A lack of magnesium balance can cause anxiety, irritability and insomnia.
Glycine-containing drugs. Glycine is an amino acid that is produced by the body and plays an important role in performing various functions human body- from musculoskeletal and metabolic to cognitive. The human body uses glycine to prepare for sleep and relax. Studies have shown that taking glycine has a positive effect on the quality of sleep in people who tend to wake up in the middle of the night. Glycine also reduces brain hyperactivity, calms nerves, and relieves anxiety, which can impair sleep. In addition, the use of glycine does not cause drowsiness in the morning, as does melatonin.
L-tryptophan. This is another amino acid necessary for the body to produce serotonin, a substance that is responsible for human mood. Serotonin also plays a crucial role in the production of melatonin. Based on these data, it is believed that taking l-tryptophan may help people suffering from insomnia get a good night's sleep. Although research on the effectiveness of l-tryptophan is limited, this supplement definitely has potential.
L-theanine- a natural alternative to melatonin, which is devoid of side effects at all. This substance has a calming effect and is used to treat stress, both physical and mental, as well as insomnia. L-theanine in the body is also responsible for regulating and generating alpha waves in the brain, which occur when the human body is completely relaxed. L-theanine helps regulate sleep and suppress beta waves, which can cause a person to wake up in the middle of the night.

Both Melatonin and its analogues cannot be a complete replacement for sleeping pills. In a placebo-controlled study of overnight sleep in insomniacs, melatonin was not superior to placebo. However, melatonin has been shown to have a sedative effect. Simply put, it promotes sleep, but does not guarantee it.

Melaxen analogue, Russian and foreign options

Preparations that contain melatonin:

Melaxen. The most advertised Russian synthetic melatonin-containing drug. Judging by the reviews, it is quite effective.
Sonnovan. Russian analogue of Melaxen, the main thing active substance which is also melatonin. It is used in the same cases as melatonin - when sleep rhythm is disturbed, after flights between time zones, when bad sleep due to mental disorders etc.
Melarithm. Also a drug, the main thing active substance which is melatonin. It costs a little more.
Mälarena. Another drug is produced at a pharmaceutical plant in the Kaluga region. The manufacturer recommends its drug for the treatment of shift syndrome, weather sensitivity and increased fatigue.
Circadin. The drug is produced in Germany or Switzerland under a license from an English company. Despite the same active substance, it costs much more.

Prescription drugs

Phenazepam. One of the oldest analogue drugs of Malaxen. A Russian drug (manufacturer: Valenta Pharmaceuticals OJSC), which has proven its effectiveness.
Phenazepam belongs to the category of tranquilizers, therefore, it should be taken only as prescribed by a doctor and with great caution - the medicine can cause addiction. In addition, there are a number of side effects.
So-called Z-group, consisting of three drugs - Zopiclone, Zaleplon and Zolpidem. Although they are produced in different countries and the duration of action and reasons for use of drugs are different, the basic properties of substances from this group are the same - they do not destroy the natural sleep cycle, do not inhibit thought processes and do not lead to addiction. A synonym for zaleplon is Andante, a synonym for zopiclone is Somnol. Zolpidem has not yet entered the Russian market.
Donormil. Very effective remedy, although it may cause dizziness and drowsiness in the morning.

Drugs without a prescription

Corvalol. A very popular product in the post-Soviet space, not least due to its low price. The main active ingredient is phenobarbital barbiturate.
. This is a drug for plant based, the components of which are selected in such a way as to provide a person with the longest and healthy sleep. The drug is available both in tablets and in the form of syrup.
Glycine. Another popular remedy in Russia, helps to relax and reduce the level of the drug. For better effect It is recommended to dissolve the tablet under the tongue shortly before bedtime.

List of Russian and foreign substitutes

Andante (Hungary) - from 130 rubles.
Glycine (Russia) - from 60 rubles.
Donormil (France) - from 160 rubles.
Corvalol (Russia) - from 20 rubles.
Melaxen (Russia) - 432 rubles.
Melarena (Russia) — 280 rub.
Melarithm (Russia) — 317 rub.
Novo-passit (Czech Republic) - from 200 rubles.
Somnol (Russia) - from 170 rubles.
Sonnovan (Russia) — 277 rub.
Phenazepam (Russia) - from 90 rubles.
Circadin (Switzerland, Germany) - 676 rubles.

I have always dealt with jet lag with the help of Melaxen, the effect is excellent, even with frequent changes time zones and slept normally. Recently, money problems arose; spending money on expensive pills has become an unaffordable luxury. I decided to try Velson, it is based on the same melatonin, and the price is much more affordable. I'm very pleased with the result. Now flights have no effect on... I have always dealt with jet lag with the help of Melaxen, the effect is excellent, even with frequent changes in time zones I slept normally. Recently, money problems arose; spending money on expensive pills has become an unaffordable luxury. I decided to try Velson, it is based on the same melatonin, and the price is much more affordable. I'm very pleased with the result. Now flights do not affect the quality of sleep at all, I fall asleep easily and when I need to.

Medicines based on melatonin are good, well tolerated by the body, there is no addiction from them, you just need to look for proven options. I took Melaxen, apparently it wasn’t for me, I didn’t really feel the effect. Velson bought it on the advice of a friend, another thing, I immediately felt the Italian quality of the ingredients)) I take it one tablet at night and have no problems with sleep.

Lisa Doban

Why did I pay so much for Melaxen when there is Velson? O_o what is there, that there are foreign raw materials, but they are charging PPC for the brand. Velson started buying it, I always get enough sleep under its influence, my nerves don’t interfere in any way, the drug doesn’t have a bad effect on getting up, on the contrary, it’s easier to get up after getting a good night’s sleep.

Kulibin

Melaxen is a good product, personally tested, but it is quite expensive. Now the family has problems with money, I can afford Velson more. It works out to be 50 percent more profitable, the effect suits me. I take it from Friday to Tuesday and am cheerful all week, there is definitely no “day off” insomnia, as well as the feeling of exhaustion on Monday

Melaxen good drug. I give it a solid four on a five-point scale. And if you experience any side effects, then this is an individual intolerance of the body.

Marina

I took Melaxen for a month, the doctor prescribed the course. On the positive side, portability is excellent, falling asleep quickly, easy awakening, lack of sleepiness during the day and does not cause addiction. The downside is that it doesn’t work right away; only after a week I was able to fall asleep and get enough sleep.

Anonymous user

May cause diabetes. See a doctor before spending money. Well, google it, if you’ve already decided to drink it, there’s cheap Vita-melatonin, the same thing, but for normal money

Anonymous user