Increased levels of monocytes and ESR in the blood. Elevated monocytes in the blood: what does this mean? Taking medications

Hemoglobin Hb

120-160 g/l for men, 120-140 g/l for women

Increased hemoglobin levels:

Diseases accompanied by an increase in the number of red blood cells (primary and secondary erythrocytosis)
Blood thickening (dehydration)
Congenital heart defects, pulmonary heart failure
Smoking (formation of functionally inactive HbCO)
Physiological reasons(for residents of high mountains, pilots after high-altitude flights, climbers, after increased physical activity)

Decreased hemoglobin levels (anemia):

Increased hemoglobin loss during bleeding - hemorrhagic anemia
Increased destruction (hemolysis) of red blood cells - hemolytic anemia
Lack of iron necessary for the synthesis of hemoglobin, or vitamins involved in the formation of red blood cells (mainly B12, folic acid) - iron deficiency or B12 deficiency anemia
Impaired formation of blood cells in specific hematological diseases - hypoplastic anemia, sickle cell anemia, thalassemia

Hematocrit Ht

40-45% for men 36-42% for women

Shows the percentage of cells in the blood - red blood cells, leukocytes and platelets in relation to its liquid part - plasma. If the hematocrit drops, the person either suffered a hemorrhage or the formation of new blood cells is sharply inhibited. This happens when severe infections and autoimmune diseases. An increase in hematocrit indicates blood thickening, for example due to dehydration.

Increased hematocrit:

Erythremia (primary erythrocytosis)
Secondary erythrocytosis (congenital heart defects, respiratory failure, hemoglobinopathies, kidney tumors accompanied by increased formation of erythropoietin, polycystic kidney disease)
Decrease in the volume of circulating plasma (blood thickening) in case of burn disease, peritonitis, etc.
Dehydration of the body (with severe diarrhea, uncontrollable vomiting, increased sweating, diabetes)

Decreased hematocrit:

Anemia
Increase in circulating blood volume (second half of pregnancy, hyperproteinemia)
Overhydration

Red blood cells RBC

4-5*1012 per liter for men 3-4*1012 per liter for women

Cells that carry hemoglobin. Changes in the number of red blood cells are closely related to hemoglobin: few red blood cells - little hemoglobin (and vice versa).

Increased red blood cell count (erythrocytosis):

Absolute erythrocytosis (caused by increased production of red blood cells)
Erythremia, or Vaquez disease - one of the options chronic leukemia(primary erythrocytosis)

Secondary erythrocytosis:

caused by hypoxia ( chronic diseases lungs, congenital heart defects, the presence of abnormal hemoglobins, increased physical activity, exposure to high altitudes)
associated with increased production of erythropoietin, which stimulates erythropoiesis (kidney parenchyma cancer, hydronephrosis and polycystic kidney disease, liver parenchyma cancer, benign familial erythrocytosis)
associated with excess adrenocorticosteroids or androgens (pheochromocytoma, Cushing's disease/syndrome, hyperaldosteronism, cerebellar hemangioblastoma)
relative - with blood thickening, when plasma volume decreases while maintaining the number of red blood cells
dehydration (excessive sweating, vomiting, diarrhea, burns, increasing swelling and ascites)
emotional stress
alcoholism
smoking
systemic hypertension

Decreased levels (erythrocytopenia):

Acute blood loss
Deficiency anemias of various etiologies - as a result of deficiency of iron, protein, vitamins
Hemolysis
May occur secondary to various types of chronic non-hematological diseases
The number of red blood cells may physiologically decrease slightly after eating, between 17.00 and 7.00, and also when taking blood in a supine position.

CPU Color Index

0.85-1.05V

The ratio of hemoglobin level to the number of red blood cells. The color index changes with various anemias: it increases with B12-, folate-deficiency, aplastic and autoimmune anemia and decreases with iron deficiency.

White blood cells WBC

3-8*109 per liter

White blood cells are responsible for fighting infections. The number of leukocytes increases with infections and leukemia. Decreased due to inhibition of leukocyte formation in bone marrow for severe infections, cancer and autoimmune diseases.

Increased levels (leukocytosis):

Acute infections, especially if their causative agents are cocci (staphylococcus, streptococcus, pneumococcus, gonococcus). Although a whole series acute infections(typhoid, paratyphoid, salmonellosis, etc.) can in some cases lead to leukopenia (decrease in the number of leukocytes)
Inflammatory conditions; rheumatic attack
Intoxications, including endogenous (diabetic acidosis, eclampsia, uremia, gout)
Malignant neoplasms
Injuries, burns
Acute bleeding(especially if the bleeding is internal: into the abdominal cavity, pleural space, joint or in close proximity to a hard meninges)
Surgical interventions
Heart attacks internal organs(myocardium, lungs, kidneys, spleen)
Myelo- and lymphocytic leukemia
The result of the action of adrenaline and steroid hormones
Reactive (physiological) leukocytosis: impact physiological factors(pain, cold or hot bath, physical activity, emotional stress, exposure to sunlight and UV rays); menstruation; birth period

Decreased level (leukopenia):

Some viral and bacterial infections (flu, typhoid fever, tularemia, measles, malaria, rubella, parotitis, infectious mononucleosis, miliary tuberculosis, AIDS)
Sepsis
Bone marrow hypo- and aplasia
Bone marrow damage chemicals, medications
Impact ionizing radiation
Splenomegaly, hypersplenism, post-splenectomy condition
Acute leukemia
Myelofibrosis
Myelodysplastic syndromes
Plasmacytoma
Metastases of neoplasms to the bone marrow
Addison-Birmer disease
Anaphylactic shock
Systemic lupus erythematosus, rheumatoid arthritis and other collagenoses
Taking sulfonamides, chloramphenicol, analgesics, non-steroidal anti-inflammatory drugs, thyreostatics, cytostatics

Neutrophils NEU

up to 70% of the total number of leukocytes

Neutrophils are cells of a nonspecific immune response; they are found in large numbers in the submucosal layer and on the mucous membranes. Their main task is to swallow foreign microorganisms. Their increase indicates a purulent inflammatory process. But you should be especially wary if there is a purulent process, but there is no increase in neutrophils in the blood test.

Increased neutrophil levels (neutrophilia, neutrophilia):

Acute bacterial infections
Localized (abscesses, osteomyelitis, acute appendicitis, acute otitis media, pneumonia, acute pyelonephritis, salpingitis, meningitis, tonsillitis, acute cholecystitis, etc.)
generalized (sepsis, peritonitis, pleural empyema, scarlet fever, cholera, etc.)
Inflammatory processes and tissue necrosis (myocardial infarction, extensive burns, rheumatism, rheumatoid arthritis, pancreatitis, dermatitis, peritonitis)
Condition after surgical intervention
Endogenous intoxications (diabetes, uremia, eclampsia, hepatocyte necrosis)
Exogenous intoxications (lead, snake venom, vaccines)
Oncological diseases(tumors of various organs)
Taking some medicines eg corticosteroids, digitalis preparations, heparin, acetylcholine
Physical stress and emotional stress and stressful situations: exposure to heat, cold, pain, burns and childbirth, pregnancy, fear, anger, joy

Decreased neutrophil levels (neutropenia):

Some infections caused by bacteria (typhoid and paratyphoid fever, brucellosis), viruses (influenza, measles, chickenpox, viral hepatitis, rubella), protozoa (malaria), rickettsia (typhus), persistent infections in elderly and weakened people
Diseases of the blood system (hypo- and aplastic, megaloblastic and iron deficiency anemia, paroxysmal nocturnal hemoglobinuria, acute leukemia)
Congenital neutropenia (hereditary agranulocytosis)
Anaphylactic shock
Splenomegaly of various origins
Thyrotoxicosis
Ionizing radiation
Exposure to cytostatics antitumor drugs
Drug-related neutropenia hypersensitivity individuals to the effects of certain medications (nonsteroidal anti-inflammatory drugs, anticonvulsants, antihistamines, antibiotics, antivirals, psychotropic drugs, drugs affecting the cardiovascular system, diuretics, antidiabetic drugs)

Eosinophils EOS

1-5% of total leukocytes

Increased levels (eosinophilia):

Decreased levels (eosinopenia):

Initial phase of the inflammatory process
Severe purulent infections
Shock, stress
Intoxication with various chemical compounds, heavy metals

Lymphocytes LYM

Cells of specific immunity. If, with severe inflammation, the indicator drops below 15%, it is important to evaluate absolute number lymphocytes per 1 microliter. It should not be lower than 1200-1500 cells.

Increased level of lymphocytes (lymphocytosis):

Infectious diseases: infectious mononucleosis, viral hepatitis, cytomegalovirus infection, whooping cough, ARVI, toxoplasmosis, herpes, rubella, HIV infection
Diseases of the blood system ( chronic lymphocytic leukemia; lymphosarcoma, heavy chain disease - Franklin disease)
Poisoning with tetrachloroethane, lead, arsenic, carbon disulfide
Treatment with drugs such as levodopa, phenytoin, valproic acid, narcotic analgesics

Decreased lymphocyte levels (lymphopenia):

Heavy viral diseases
Miliary tuberculosis
Lymphogranulomatosis
Aplastic anemia
Pancytopenia
Kidney failure
Circulatory failure
Terminal stage oncological diseases
Immunodeficiencies (with T-cell deficiency)
X-ray therapy
Taking drugs with a cytostatic effect (chlorambucil, asparaginase), glucocorticoids

Platelets PLT

170-320* 109 per liter

Platelets are the cells responsible for stopping bleeding - hemostasis. And they, like scavengers, collect on the membrane the remnants of inflammatory wars - circulating immune complexes. A platelet count below normal may indicate an immunological disease or severe inflammation.

Increased levels (thrombocytosis):

Primary thrombocytosis (as a result of proliferation of megakaryocytes)
Essential thrombocythemia
Erythremia
Myeloproliferative disorders (myeloid leukemias)
Secondary thrombocytosis (occurring against the background of any disease)
Inflammatory processes (systemic inflammatory diseases, osteomyelitis, ulcerative colitis, tuberculosis)
Cirrhosis of the liver
Acute blood loss or hemolysis
Condition after splenectomy (for 2 months or more)
Oncological diseases (cancer, lymphoma)
Conditions after surgical intervention(within 2 weeks)

Decreased level (thrombocytopenia):

Congenital thrombocytopenias:

Wiskott-Aldrich syndrome
Chediak-Higashi syndrome
Fanconi syndrome
May-Hegglin anomaly
Bernard-Soulier syndrome (giant platelets)

Acquired thrombocytopenia:

Idiopathic autoimmune thrombocytopenic purpura
Drug-induced thrombocytopenia
Systemic lupus erythematosus
Thrombocytopenia associated with infection (viral and bacterial infections, rickettsiosis, malaria, toxoplasmosis)
Splenomegaly
Aplastic anemia and myelophthisis (replacement of bone marrow by tumor cells or fibrous tissue)
Tumor metastases to the bone marrow
Megaloblastic anemias
Paroxysmal nocturnal hemoglobinuria (Marchiafava-Micheli disease)
Evans syndrome (autoimmune hemolytic anemia and thrombocytopenia)
DIC syndrome (disseminated intravascular coagulation)
Massive blood transfusions, extracorporeal circulation
During the neonatal period (prematurity, hemolytic disease newborns, neonatal autoimmune thrombocytopenic purpura)
Congestive heart failure
Renal vein thrombosis

ESR - erythrocyte sedimentation rate

10 mm/h for men 15 mm/h for women

An increase in ESR signals an inflammatory or other pathological process. Increased without visible reasons for ESR should not be ignored!

Increase (acceleration of ESR):

Inflammatory diseases of various etiologies
Acute and chronic infections (pneumonia, osteomyelitis, tuberculosis, syphilis)
Paraproteinemia (multiple myeloma, Waldenström's disease)
Tumor diseases (carcinoma, sarcoma, acute leukemia, lymphogranulomatosis, lymphoma)
Autoimmune diseases (collagenoses)
Kidney diseases (chronic nephritis, nephrotic syndrome)
Myocardial infarction
Hypoproteinemia
Anemia, condition after blood loss
Intoxication
Injuries, bone fractures
Condition after shock, surgical interventions
Hyperfibrinogenemia
In women during pregnancy, menstruation, and the postpartum period
Elderly age
Taking medications (estrogens, glucocorticoids)

Decrease (slowdown of ESR):

Erythremia and reactive erythrocytosis
Severe symptoms of circulatory failure
Epilepsy
Fasting, decline muscle mass
Taking corticosteroids, salicylates, calcium and mercury preparations
Pregnancy (especially 1st and 2nd semester)
Vegetarian diet
Myodystrophies

Agranulocytosis- a sharp decrease in the number of granulocytes in the peripheral blood until their complete disappearance, leading to a decrease in the body’s resistance to infection and the development of bacterial complications. Depending on the mechanism of occurrence, a distinction is made between myelotoxic (arising as a result of the action of cytostatic factors) and immune agranulocytosis.

Monocytes- the largest cells among leukocytes, do not contain granules. They are formed in the bone marrow from monoblasts and belong to the system of phagocytic mononuclear cells. Monocytes circulate in the blood for 36 to 104 hours, and then migrate into tissues, where they differentiate into organ- and tissue-specific macrophages.

Macrophages plays a vital role in the processes of phagocytosis. They are capable of absorbing up to 100 microbes, while neutrophils are only 20-30. Macrophages appear at the site of inflammation after neutrophils and exhibit maximum activity in an acidic environment, in which neutrophils lose their activity. At the site of inflammation, macrophages phagocytize microbes, dead leukocytes, and damaged cells of inflamed tissue, thereby cleaning the site of inflammation and preparing it for regeneration. For this function, monocytes are called “the body’s wipers.”

Increased levels of monocytes (monocytosis):

Infections (viral (infectious mononucleosis), fungal, protozoal (malaria, leishmaniasis) and rickettsial etiology), septic endocarditis, as well as the period of convalescence after acute infections
Granulomatosis: tuberculosis, syphilis, brucellosis, sarcoidosis, ulcerative colitis (nonspecific)
Blood diseases (acute monoblastic and myelomablastic leukemia, myeloproliferative diseases, myeloma, lymphogranulomatosis)
Systemic collagenoses (systemic lupus erythematosus), rheumatoid arthritis, periarteritis nodosa
Poisoning with phosphorus, tetrachloroethane

Decreased monocyte count (monocytopenia):

Aplastic anemia (bone marrow damage)
Hairy cell leukemia
Surgical interventions
Shock conditions
Taking glucocorticoids

Basophils- the smallest population of leukocytes. The lifespan of basophils is 8-12 days; The circulation time in peripheral blood, like all granulocytes, is short - a few hours. The main function of basophils is to participate in anaphylactic reaction immediate hypersensitivity. They are also involved in delayed reactions through lymphocytes, inflammatory and allergic reactions, in the regulation of permeability vascular wall. Basophils contain such biologically active substances, like heparin and histamine (similar to mast cells connective tissue).

Monocytes are a type of white blood cell (leukocyte) that are responsible for protecting human body from tumor cells and pathogenic microorganisms, as well as for the resorption and elimination of dead tissue. Thus, these cells cleanse the body, which is why they are also called “janitors”.

The clinical significance of monocytes in a blood test is that their level can suggest the presence of a particular disease. Experts recommend that both adults and children undergo a general blood test twice a year for prevention in order to promptly identify deviations from the norm.

Today we want to tell you why a child may have elevated monocytes and who to contact in this case.

IN medical literature You can also find other names for monocytes, for example, mononuclear phagocytes, macrophages or histiocytes.

Macrophages are one of the main immune cells. Their role for the body is to fight pathogenic microorganisms (viruses, bacteria, fungi), waste products of microbes, dead cells, toxic substances and cancer cells.

Macrophages remain working in the pathological focus even after neutralizing the foreign agent in order to process the dead pathogenic microorganisms, decayed tissues of the body, due to which they are called “orderlies”, “cleaners” or “janitors” of the body.

In addition, macrophages prepare the body for recovery by enclosing the lesion with a “wall” that prevents the spread of infection to intact tissues.

The norm of monocytes in the blood of children: table

In most cases, the relative number of monocytes in the blood is determined, that is, the number of a given type of leukocyte is indicated as a percentage (%) in relation to other types of white blood cells.

As you can see, the levels of monocytes in the blood change with the age of the child.

Also, the doctor who ordered a general blood test may require the laboratory assistant to provide an absolute number of monocytes, which also depends on the age of the child.

Level of monocytes in the blood: how to determine?

The leukocyte formula is the percentage of individual types of white blood cells, such as neutrophils, basophils, lymphocytes, monocytes and eosinophils. Changes in the leukocyte formula are markers of various diseases.

Blood for analysis is taken from a child’s toe or heel, depending on his age, and in rare cases, from a vein.

How to prepare for a general blood test?

The well-known television pediatrician Komarovsky focuses his attention in his program on a general blood test on the fact that the objectivity of the results depends on the correct preparation for the study, therefore It is important to observe the following principles:

blood is donated exclusively on an empty stomach, since after eating the white blood cells in the blood increase. If a blood test is performed infant, then the interval between the last feeding and blood sampling should be at least two hours;
the day before blood sampling, the child must be ensured calm and protected from stress, as well as from physical activity and active games;
It is not recommended to give your child fatty foods on the eve of a blood test;
If the child is taking any medications, this should be reported to the doctor who referred him for a blood test, since some drugs can provoke monocytosis.

Monocytosis is an increase in the level of monocytes in the blood, which can be determined by a general blood test.

Monocytosis is not a separate nosological form, but a symptom of many diseases.

Elevated monocytes in a child, depending on the reasons, may be accompanied by a variety of symptoms, namely:

It is customary to distinguish between absolute and relative monocytosis.

Absolute monocytosis is diagnosed when the general blood test shows “increased absolute monocytes.”

With relative monocytosis, there is an increase in the percentage of monocytes against the background normal amount leukocytes by reducing the number of other types of white blood cells.

Elevated monocytes in a child’s blood: reasons

The following diseases can lead to an increase in monocytes in children:

Infectious mononucleosis;
brucellosis;
malaria;
toxoplasmosis;
roundworm infestation;
syphilis;
lymphoma;
leukemia;
rheumatoid arthritis;
inflammation of the mucous membrane digestive tract(gastritis, enteritis, colitis and others);
intoxication with phosphorus or tetrachloroethane.

Monocytosis can also be detected in children who have had an infectious disease, removal of tonsils, adenoids, as well as during the period of teething and changing teeth.

Monocytes are elevated in a child: examples of interpretation of the results of a general blood test

Of clinical significance is not only the increased content of monocytes in the blood, but also the combination of monocytosis with deviations of other hematological parameters. Let's look at examples.

An increased level of monocytes in the blood can be a sign of a fairly serious pathology, so in no case should it be ignored. If you receive a blood result in which monocytosis is present, you must consult a pediatrician for additional examination.

Children with suspected infectious diseases must be referred for consultation to an infectious disease specialist.

If there are symptoms of an intestinal infection, the child is prescribed a coprogram, stool analysis for helminth eggs, bacteriological examination of stool, culture of vomit, ultrasonography abdominal organs, general urine analysis, as well as specific serological tests to exclude diseases such as syphilis, brucellosis, malaria, etc.

For children who have signs of lymphadenopathy (enlarged lymph nodes), atypical mononuclear cells must be determined to exclude infectious mononucleosis, or a bone marrow puncture is performed if leukemia is suspected. In the latter case, a consultation with a hematologist is indicated.

If monocytosis is combined with heart murmurs or joint pain, then such children are referred for examination to a cardio-rheumatologist, who can prescribe a biochemical blood test and rheumatic tests.

If you have monocytosis and abdominal pain, nausea and vomiting, you should consult a surgeon, as this may be a manifestation of appendicitis, stomach ulcers, colitis, etc.

Treatment of monocytosis consists of eliminating its cause.

Determine why increased amount monocytes in a child’s blood can only be determined by a specialist – a pediatrician. You may also need to consult related specialists, such as an immunologist, hematologist, infectious disease specialist, surgeon, phthisiatrician, etc.

Many diseases can be detected only with the help of a general clinical blood test. Erythrocyte sedimentation rate (ESR) is one of the indicators of this study. During the analysis, the blood interacts with an anticoagulant (sodium citrate) and its cells (erythrocytes) settle to the bottom of the tube. Erythrocyte sedimentation rate measurements are carried out over an hour.

How red blood cells work

Over a certain period of time, red blood cells unite into larger formations (agglomeration) and settle on the walls of vertical vessels. It is worth noting that the ESR indicator is never assessed separately from others - the level of red blood cells, leukocytes, platelets.

However increased ESR or a decrease in the indicator indicates that there are some diseases in the body at the acute stage. In newborns this indicator is low, but this is a natural phenomenon. It increases as the child grows.

Norms for children of different ages:

Newborns – 2-2.8;
Up to a year – 4-7;
From 1 to 8 years – 4-8;
From 8 to 12 – 4-12;
Over 12 years old – 3-15.

Methods for determining ESR in a child’s blood

Now two methods are used to determine this indicator: the Panchenkov and Westergren method.
The first is indoors. biological fluid on glass installed vertically. The second is more accurate, since it optimally recreates the conditions of this process in the body. Normally, the indicators of both analyzes are the same. The Westergren method is more sensitive because it uses venous blood and vertical tubes. If the results of the Westergren analysis show an increase in the erythrocyte sedimentation rate, then a retake is not required, the information is reliable.

Increased ESR: what could a child have?

Quite often, the disorder is discovered during a routine visit to the pediatrician. If the doctor does not see the reasons that led to the deviation, retaking the tests at another time of the day or using a different method is prescribed, and then additional research may be required.

In addition, other indicators of general and biochemical analysis of blood and urine are taken into account, an external examination of the child is carried out, and an anamnesis is collected from the words of the parents. For example, with a simultaneous increase in the level of leukocytes, an acute inflammatory process can be suspected.

If the rate is high, but leukocytes are within normal limits, this may indicate a number of viral infections, or the onset of recovery (leukocytes reach normal limits earlier than ESR).

Causes of elevated ESR found in the blood of a child

This figure may change due to large quantity reasons, both physiological and pathological. For example, it is slightly higher in girls than in boys. Natural fluctuations are observed in different periods of the day, for example, from 13 to 18 hours the speed may increase slightly. There are periods when natural fluctuations occur: 28-31 days from birth, 2 years of age. At this time, the indicator can increase to 17 mm/h.

During the acute course of diseases, the protein composition of plasma changes. Increases concentration
haptoglobin, C-reactive protein, which, accordingly, entails an increase in ESR. A possible provoking factor may be reduced blood viscosity and the formation of immature forms of red blood cells. In the presence of acute inflammation an increase in this indicator is observed within 24 hours after the temperature rises. In chronic inflammation, the effect is exerted by an increase in the level of immunoglobulins and fibrinogen. Anemia also leads to this.

What does an elevated ESR diagnosed in a child’s blood indicate?

Most often, the causes are hidden in the presence of an acute or subacute inflammatory process. This phenomenon can also be caused by various injuries, poisoning, allergies, helminthic infestations, untreated foci of infections. One factor is stress.

In addition, there are many serious pathologies that affect the ESR rate, causing its growth:

Flu, ARVI, sore throat, respiratory system diseases;
Inflammatory processes in tissues and organs;
Septic and purulent processes, organ tuberculosis;
Connective tissue pathologies, a number of autoimmune conditions;
Thyroid diseases;
Metabolic disorder;
Anemia;
A number of oncological pathologies.

In infants, this is most often observed against the background of the following conditions: teething; vitamin deficiency; presence in breast milk large amounts of fat; taking medications that contain ibuprofen or paracetamol. Also, this phenomenon can be completely natural, that is, it can be an individual norm of the body. In the latter case, it is recommended to undergo regular tests.

It happens that everything is normal, but only increased ESR indicators. False-positive acceleration can be triggered by the baby's obesity, a decrease in the level of red blood cells and hemoglobin, taking certain vitamins, frequent allergies, and vaccination against hepatitis.

The doctor must additionally examine the tonsils, lymph nodes, palpate the spleen, examine the kidneys in different body positions, listen to the heart, prescribe an ECG, X-ray of the lungs, a blood test for protein, platelets, reticulocytes, immunoglobulins.

If the doctor fails to connect the increase in this indicator with any pathology even after a thorough diagnosis, then this fact is correlated with individual characteristics baby.

Monocytes and ESR are elevated in the child’s blood

Monocytes are immature blood cells, which were already mentioned above. Monocyte levels can also be determined through a general blood test. If more detailed information is needed, the leukocyte formula is analyzed, in which monocytes are included in its composition. Both increased and decreased levels indicate a disruption in the functioning of the body. An increase in their level is called monocytosis. In medicine, it is considered normal if the number of immature cells is up to 11% of the total number of leukocytes.

If their level decreases, disorders in the immune system are suspected. This often occurs when
bone marrow damage, for example, with aplastic anemia or vitamin B12 deficiency. In addition, this is possible with radiation sickness and hairy cell leukemia.

Average hemoglobin concentration in erythrocytes (MCHC) -35.6

Platelets (PLT) -316

Red blood cell division width (RDW-SD) - 36.1

Red blood cell distribution width (RDW-CV) -12.8

Platelet distribution width behind platelets (PDW) - 12.7

Median platelet volume (MPV) - 10.3

Thrombocrit (PCT) - 0.33

Neutrophils (per 100 leukocytes) - 40.3

Neutrophils (abs.) -2.1

Lymphocytes (per 100 leukocytes) - 46.9

Lymphocytes (abs.) -2.45

Monocytes (per 100 leukocytes) -10.3 (normal 2-10)

Monocytes (abs.) -0.54

Eosinophils (per 100 leukocytes) -2.3

Eosinophils (abs.) -0.12

Basophils (per 100 leukocytes) - 0.2

Basophils (abs.) -0.01

They said that the increase in red blood cells was due to a lack of fluid (the child really drank little water), for the past 4 months we have been drinking enough water, but the red blood cells are the same), monocytes had not risen before.

The child has elevated monocytes in the blood

How is the level of monocytes determined?

You can find out how many monocytes are in a child’s blood from general analysis blood. This study shows the total number of all leukocytes, as well as the percentage of their individual types (it is called a leukogram or leukocyte formula).

By assessing the percentage of one or another type of white blood cells, one can judge the presence of an inflammatory, infectious or other pathological process in the child’s body. It is on the basis of the results of a blood test with a leukogram that the pediatrician refers the child for additional examinations, also taking into account clinical picture, past illnesses and other factors.

Blood for assessing the leukocyte formula is usually taken from a finger; sampling from a vein is used much less frequently. In newborn infants, due to very small toes, a heel fence is used. In order for the level of monocytes in the blood in the test results to be reliable, it is important:

Bring your child to donate blood on an empty stomach, because eating leads to temporary leukocytosis. Before taking blood, it is only permissible to drink water small quantity. It is not recommended to consume any other drinks or foods, nor to drink too much, as this will affect the results. If the test is performed on an infant, at least two hours must pass after feeding before the blood sample is taken.
The child must be calm, as emotional stress affects the results of the blood test.
Age must be indicated on the analysis form, since this is the main condition for correct decoding result.
On the eve of a blood test, active physical activity and fatty foods are undesirable. Such factors lead to false leukogram results.
If your baby is prescribed any medications, this should be reported to the doctor before he begins to interpret the analysis, since some medications can affect the concentration of different types of white blood cells.

What level of monocytes will be elevated?

The normal content of monocytes is determined by the age of the child:

In newborns, the number of such white cells should not exceed 10% of all leukocytes.
From the fifth day after birth, the level of monocytes increases slightly, but no more than 14% of the total number of white cells.
By the end of the first month of life, monocytes begin to decrease. For a child aged 1 month, the norm in the leukogram is no more than 12% monocytes.
The leukocyte formula in the analysis of children from one to 4-5 years old contains no more than 10% monocytes.
At the age of five, 4-6% of all leukocytes are considered normal. This leukogram indicator is typical for children 5-15 years old.
In adolescents over 15 years of age, the normal level of monocytes does not exceed 7%.

If it is found in the child's blood increased value(more than the indicated numbers), this condition is called monocytosis.

Types of monocytosis

Depending on the cause of the change in leukogram, monocytosis can be:

Absolute. The number of leukocytes increases due to more monocytes This variant of monocytosis reflects an active immune response child's body and often indicates the presence of a pathological process at the time of examination.
Relative. The percentage of monocytes is higher due to a decrease in the percentage of other white blood cells, and the total number of white blood cells may not increase. Such monocytosis is not very informative and often occurs after an illness or recent injury, and may also be a normal variant due to a hereditary trait.

Causes of monocytosis

A slight increase in monocytes occurs with purulent infections and during the recovery period after colds. Such an unexpressed change in the blood in the form of relative monocytosis occurs during teething, severe bruise or injury. Also, a slight excess may be due to a hereditary factor.

If monocytosis is a symptom of a serious illness, it is usually severe. For diseases circulatory system The child is unable to cope with large numbers of pathogens or other harmful particles, resulting in monocytes being produced in the bone marrow in greater numbers than in healthy children.

A high percentage of monocytes is detected when:

In addition, monocytosis is possible with:

Ulcerative colitis, esophagitis, enteritis and others inflammatory processes in the gastrointestinal tract.
Fungal infection.
Infective endocarditis.
Sepsis.
Surgical treatment, for example, for appendicitis.

Symptoms

What to do

As a rule, a slight increase in monocytes is not dangerous, because it can be provoked by various factors, including hereditary ones. If the numbers are high, this is an alarming signal of “problems” in the functioning of the child’s body.

A child with monocytosis will be sent for additional tests and will also be examined by specialists. Presence in the baby's blood large number The presence of monocytes indicates the activity of the pathological process and its progression, so the reason for this blood test result should be identified as quickly as possible. Once the doctor makes a diagnosis and prescribes appropriate therapy, the child’s condition will improve and the monocyte level will gradually return to normal.

Elevated erythrocytes, monocytes, and lymphocytes of the child

Child 2 years 3 months. There are no complaints, only an allergy to something that scratches my butt and stomach, we donated blood for food allergens and decided to do a blood test at the same time. and here it is

Increased red blood cells. lymphocytes, monocytes and decreased neutrophils.

At 8 months I had Staphylococcus, treated with phages, at 1.5 years I was tested, Staphylococcus. Not found.

The pediatrician says to take a stool test. Could this really be due to worms?

just in case, full analysis:

Name/indicator Value Reference values *

Leukocytes (WBC) 11.72 *10^9/l 5.5 - 15.5

Red Blood Cells (RBC) #8593; 5.26 *10^12/l 3.8 - 4.8

Hemoglobin (HGB) 139 g/l

Hematocrit (HTC) 38.8%

Mean erythrocyte volume (MCV) 73.8 fL

Avg. sod. hemoglobin in er-te (MCH) 26.4 pg

Avg. conc. hemoglobin in er-te (MCHC) 358 g/l

Platelets (PLT) 251 *10^9/l

Distribution erith. according to V - standard deviation (RDW-SD) #8595; 36.5 fL 37.2 - 54.2

Distribution erith. according to V - coefficient. variac(RDW-CV) 13.8 % 11.3 - 19.5

Distribution platelet volume (PDW) 10.5 fL

Mean platelet volume (MPV) 9.80 fL 9.4 - 12.4

Large platelet count ratio (P-LCR) 24.0%

Neutrophils (NE) 2.08 *10^9/l 1.78 - 5.38

Lymphocytes (LY) 8.20 *10^9/l 5.0 - 17.0

Monocytes (MO) #8593; 0.89 *10^9/l 0.3 - 0.82

Eosinophils (EO) 0.48 *10^9/l 0.04 - 0.54

Basophils (BA) 0.07 *10^9/l 0 - 0.08

Neutrophils, % (NE%) #8595; 17.7%

Lymphocytes, % (LY%) #8593; 70.0%

Monocytes, % (MO%) 7.6 % 3 - 9

Eosinophils, % (EO%) 4.1 % 1 - 6

Basophils, % (BA%) 0.6 % 0 - 1.2

Neutrophils, % (NE%) (microscopy) #8595; 31%

Neutrophils: rods. (microscopy) 1% 1 - 6

Neutrophils: segment. (microscopy) #8595; thirty %

Lymphocytes, % (LY%) (microscopy) 55%

Monocytes, % (MO%) (microscopy) #8593; 10% 3 - 9

Eosinophils, % (EO%) (microscopy) 4% 1 - 6

Basophils,% (BA%) (microscopy) 0% 0 - 1.2

Erythrocyte sedimentation rate (ESR)

Settlement rate 2 mm/h

to your health. there are doctors there

Don't panic!))) There is nothing critical in the analysis. There is an increase in several indicators in percentage and absolute values (red blood cells in the first place) - most likely, a small hemoconcentration, in simple words thickening of the blood (this is also indicated by the hematocrit approaching upper limit norms). If you brought your child in for analysis hungry in the morning, you didn’t give him anything to drink in the morning and he didn’t drink liquids in the evening, the house is dry and hot - this fully explains it. As for leukocytes, look at the absolute values, not the percentages - they are normal (where there are deviations, they are minimal and may simply be a calculation error). With smear microscopy, an increase in monoliths by 1% may not mean anything, a decrease in neutrophils is relative - their absolute number is normal).

Show the test to your pediatrician, and retake the clinical blood test after 10 days.

Signs helminthic infestation By clinical analysis there is no blood, first of all there will be high eosinophils, basophils may appear.

I looked at the past tests in the card now, monocytes were 3-7, neutrophils 16-24, lymphocytes 60-70, but red blood cells 4.0-4.2.

Blood was not donated on an empty stomach; approximately 2 hours before the test, the child drank 150 ml of juice.

vBulletin v3.8.7, Copyright, Jelsoft Enterprises Ltd.

General blood analysis

general description

White blood cells (WBC)

White blood cells (WBC) are the basis of the body's antimicrobial defense. Under normal conditions, there are five types of leukocytes in the peripheral blood: granulocytes (neutrophils), eosinophils, basophils, monocytes and lymphocytes.

A blood test is characterized by an increase in the number of white blood cells (leukocytosis) with:

Infections (bacterial, fungal, viral);
Inflammatory conditions;
Malignant neoplasms;
Tissue crushing;
Leukemia;
Uremia;
The effects of adrenaline and steroid hormones.

A blood test is characterized by a decrease in the number of leukocytes (leukopenia) with:

Bone marrow aplasia and hypoplasia;
Bone marrow damage chemicals, medications;
Irradiation;
Hypersplenism;
Aleukemic forms of leukemia;
Myelofibrosis;
Myelodysplastic syndrome;
Plasmacytoma;
Metastases of neoplasms to the bone marrow;
Addison-Birmer's disease;
Sepsis;
Typhoid and paratyphoid;
Anaphylactic shock;
Collagenoses.

White blood cell (WBC) standard

Red blood cells (RBC)

Red blood cells (RBCs) are highly specialized cells whose main job is to transport oxygen from the lungs to the tissues and carbon dioxide back to the lungs.

A blood test is characterized by an increase in the number of red blood cells (erythrocytosis) in the following diseases:

congenital and acquired heart defects, cor pulmonale, emphysema, exposure to significant altitudes;
polycystic kidney disease, hydrocele of the renal pelvis, hemangioma, hepatoma, pheochromocytoma, the effect of corticosteroids, Cushing's disease and syndrome;
dehydration.

A blood test is characterized by a decrease in the number of red blood cells (erythropenia) in the following diseases:

Anemia;
Acute blood loss;
IN late dates pregnancy;
Overhydration.

Red blood cell (RBC) rate

Viral or bacterial? Severely elevated ESR and monocytes

General clinical blood test (23 indicators)

Hemoglobin (HGB) 127 g/l ()

Help with a blood test, please!

The child has been sick since Saturday - first his voice dropped, then a rough cough appeared, on the night of Monday to Tuesday the temperature rose (up to 38.7), lasted for one day, and easily went down. There was no fever last night or today. The doctor listened today - there is no wheezing in the lungs, but a runny nose - until yesterday the nose was running non-stop, now there is very thick white-yellowish snot. The cough is rare, when lying down, wet. The throat is still reddish and loose. I donated blood in the morning, and this is what came back (((What could this mean? Usually I understand from the analysis that it’s viral or bacterial blood, but here it’s a mystery to me. ESR is greatly increased, red blood cells and monocytes are elevated.

Laboratory norms in brackets, by age)

Erythrocyte sedimentation rate (ESR), capillary photometry method

Settlement rate 19 mm/h (2 - 20)

General clinical blood test (23 indicators)

Leukocytes (WBC) 9.89 *10^9/l (5..50)

Red blood cells (RBC) 5.06 *10^12/l (3.00 - 4.40)

Hemoglobin (HGB) 127 g/l ()

Hematocrit (HTC) 39.5% (32.0 - 42.0)

Mean erythrocyte volume (MCV) 78.1 fL (73.0 - 85.0)

Avg. sod. hemoglobin in er-te (MCH) 25.1 pg (25.0 - 31.0)

Avg. conc. hemoglobin in er-te (MCHC) 322 g/l ()

Platelets (PLT) 342 *10^9/l ()

Distribution erith. according to V - standard deviation (RDW-SD) ↓ 36.8 fL (37.0 - 54.0)

Distribution erith. according to V - coefficient. variac(RDW-CV) 13.2% (11.3 - 19.5)

Distribution platelet count by volume (PDW) 13.4 fL (10.0 - 20.0)

Mean platelet volume (MPV) 10.80 fL (9..40)

Large platelet ratio (P-LCR) 31.9% (13.0 - 43.0)

Neutrophils (NE) 4.65 *10^9/l (1.50 - 8.00)

Lymphocytes (LY) 3.76 *10^9/l (1.50 - 7.00)

Monocytes (MO) 1.25 *10^9/l (0.05 - 0.40)

Eosinophils (EO) 0.19 *10^9/l (0.02 - 0.30)

Basophils (BA) 0.04 *10^9/l (0.00 - 0.08)

Neutrophils, % (NE%) 47.1% (32.0 - 58.0)

Lymphocytes, % (LY%) 38.0% (33.0 - 50.0)

Monocytes, % (MO%) 12.6% (3.0 - 12.0)

Eosinophils, % (EO%) 1.9% (1.0 - 7.0)

Basophils,% (BA%) 0.4% (0.0 - 1.2)

* - Reference values are given taking into account age, gender, phase menstrual cycle, gestational age

Help! Otherwise, in the morning I’ll give all this to the doctor, and I don’t understand whether ab are needed or not, I want to somehow prepare, or something.

Yes, the temperature all day is from 36.8 to 37.2 (in the evening). Yesterday it was 38.7, at night 37.5, then it fell.

Why didn’t you like viruses? everything can happen.

this is an organism, especially a child’s one

although your first post clearly describes at least laryngitis, possibly laryngotracheitis. I would take him to another doctor to listen to Bunny and Luntik 10/22/2005

I’m for viruses) it just hasn’t happened yet that the temperature dropped, and after 18 hours it rose again (and I always understood everything myself by looking at the blood).

In fact, two doctors looked/listened to the child - on Monday a doctor from the clinic, an unknown one, on Wednesday - our pediatrician from the same clinic. On Monday, the doctor said that there might be laryngitis and laryngotracheitis, but at that time it did not exist yet, and she diagnosed rhinopharyngitis. As a result, apparently, the throat and trachea were successfully treated, and everything went away there (the voice is already normal, there was no cough yesterday), but the nose went away - today there is already thick green snot. After a telephone consultation, I started injecting Polydex. It’s just that no one is working tomorrow.

In general, everything seemed to suddenly happen. I have already lost the habit of such diseases.

Why are monocytes elevated and red blood cells elevated?

The situation when a person’s monocytes are elevated and red blood cells are elevated indicates that pathology is developing in the body and it is necessary to take Urgent measures to eliminate the causes of this condition. The phenomenon in which the level of monocytes and red blood cells increases is called monocytosis and erythrocytosis, respectively. Both the one and the other can be relative and absolute. Of particular danger are absolute monocytosis and erythrocytosis.

Functions of monocytes and erythrocytes

Monocytes belong to leukocytes, more precisely, they are one of the types of agranulocytes, which means the role they perform in the human body is the same, namely:

Serve as protection against the penetration of harmful biological agents.
Cleanses the blood.
Capable of creating conditions for the restoration of tissue cells as a result various damages or inflammatory processes.

Monocytes are quite large cells; they react to the influence of foreign agents and can absorb them. Thus, the human body gets rid of “aliens”, which helps to avoid many diseases, including life-threatening ones.

After the body is cleansed of “biological debris,” thanks to monocytes, tissues are restored faster, inflammation goes away, and even tumors disappear.

As for red blood cells, their role for human health is no less important. If we literally translate the name of these cells (“red cell”), this will explain their main function.

actively participate in the process of hematopoiesis;
are transporters of carbon dioxide and oxygen to cells;
cleanse the body of waste products;
prevent the process of intoxication of the body;
serve as protection against toxins;
allow you to achieve and maintain a normal acid-base balance.

These cells, which do not have nuclei, protect, nourish (carry oxygen), and allow blood to clot.

Reasons for the increase in indicators

Standard indicators for the number of red blood cells differ from person to person.

the age of the person (in children, as they grow older, their number increases, and in older people, it decreases slightly);
men have more of them than women (this difference begins to appear from the age of 12 in adolescence);
state of human health.

Monocytes in the blood are measured in relation to the total number of white blood cells. Their content is not directly dependent on gender or age.

What factors contribute to the increase in monocytes and red blood cells in human blood?

An increase in monocytes suggests:

Development of tumor processes.
The development of an infectious disease (possibly influenza, diphtheria, rubella, etc.).
Diseases associated with connective tissue pathology, for example, lupus erythematosus, polyarteritis nodosa or rheumatism.
Tuberculosis affecting joints, lungs, bones.

Determination in blood high content red blood cells may have the following reasons:

problems with the respiratory system;
pathology of the hematopoietic system;
pathologies of the heart muscle;
pulmonary hypertension;
respiratory failure due to obesity (Pickwick syndrome);
diseases associated with the penetration of infections into the body;
oncological diseases of the liver or kidneys.

In addition, red blood cells can also increase due to a long trip to the mountains, when the body suffers from thin air and insufficient oxygen in it. A person’s condition returns to normal after he leaves the mountains; this does not require medical intervention.

Red blood cells are so sensitive to various types of harmful agents that they begin to actively form in response to dirty water or water with a high chlorine content entering the body.

The presence of increased levels of these red blood cells in the blood may indicate an increase in blood viscosity, and this, in turn, can lead to the formation of blood clots and pose a threat to human life.

There are several types of blood cells. Each of them has its own indicators in the blood. By various reasons they can go up or down. High level monocytes and leukocytes increases the suspicion of the presence of a serious pathology in the human body.

How to protect yourself?

Since there are many reasons for this situation, information is needed about:

presence of chronic diseases;
time of onset of the first signs;
general state of human health.

If the increase in indicators is associated with pregnancy or recent surgery, then the patient is only observed and repeated analysis is taken after a while. Erythrocytosis may be a consequence stressful situation, in this case, you only need to carry out therapy in order to normalize the functioning of the human nervous system.

The doctor needs to be extremely careful to accurately determine the disease. To do this, it is important to know all the symptoms.

Additional laboratory tests are often used to confirm the diagnosis. There are diseases that, unfortunately, are incurable. The doctor’s task in this case is to alleviate the patient’s condition and prescribe appropriate therapy.

Both monocytosis and erythrocytosis are quite dangerous conditions, so they cannot be ignored, as this can result in tragedy.

Child under one year old

Increased red blood cells and monocytes in blood tests

Hello, on 05/10/2017 we took a general blood test from a vein and the red blood cells and monocytes were elevated, there was snot and a cough, the pediatrician diagnosed ARVI, said to retake it in two weeks, we retested it today 06/04/2017, the picture has not changed, we haven’t been coughing for more than two weeks , no snot, everything is fine, but red blood cells and monocytes are still exactly elevated, why? and with such an analysis we can have a planned operation, circumcision, 2 Hemoglobin 04/06/g/l 108 – 132 completed 3 Red blood cells 04/06/2017 4.77 ++ x10*12/l 4.0 – 4.4 completed 4 Hematocrit 04/06 /.9 % 32 – 42 completed 5 Mean erythrocyte volume (MCV) 06/04/fl 77 – 83 completed 6 Mean erythrocyte Hb content (MCH) 06/04/.8 pg 22.7-32.7 completed 7 Average Hb concentration in erythrocytes (MSNS) 04/06/g/l 336 – 344 completed 8 Color index 04/06/2017 0.81 - 0.85 – 1.00 completed 9 Platelets 04/06/x10*9/l 196 – 344 completed 10 Leukocytes 04/06/2017 7.57 x10*9/l 5.5 – 15.5 completed 11 Immature granulocytes 06/04/2017 0.01 10*9/l 0 – 0.06 completed 12 Immature granulocytes % 06/04/2017 0.1 % 0 – 0.8 completed 13 Segmented neutrophils 04/06 / 2017 2.95 x10*9/l 1.50 – 8.00 completed 14 Segmented neutrophils % 04/06/.9 % 34 – 54 completed 15 Eosinophils 04/06/2017 0.13 x10*9/l 0.02 – 0.30 completed 16 Eosinophils % 06/04/2017 1.7% 1 – 5 completed 17 Basophils 06/04/2017 0.05 x10*9/l 0 – 0.07 completed 18 Basophils % 06/04/2017 0.7% 0 – 1 completed 19 Monocytes 06/04/2017 0.67 x10*9/l 0.00 – 0.80 completed 20 Monocytes % 06/04/2017 8.9 ++ % 4 – 8 completed 21 Lymphocytes 06/04/2017 3.77 x10*9/l 1.50 – 7.00 completed 22 Lymphocytes % 04/06/. 8% 33 – 53 completed 23 ESR (Westergren) 04/06/mm/hour 0 – 10 completed

Hello, Natalia. On the background viral infection the child may experience various changes in the formula - an increase in red blood cells may be associated with loss of fluid or insufficient drinking regimen, if they have not returned to normal - the situation has not changed. But the indicator is not critical. Monocytes are markers of the activity of the immune system in the fight against infection; ESR increases due to inflammation in the body; they can take a long time to return to normal. The decision on the possibility of surgical intervention is made by the attending physician and not only on the basis of laboratory parameters, higher value has an examination of the child and the presence or absence of complaints. Retake the test and based on it, you can make a decision about surgery. Phimosis is also inflammation and this can leave indicators at this level. All the best!

What can cause elevated monocytes in children?

The results of a general blood test or its leukocyte formula.

This leukocyte formula includes the main content indicators different types leukocytes - white blood cells: lymphocytes, eosinophils, monocytes and their percentage.

Also, this blood test method shows the level of red blood cells and their sedimentation rate (ESR).

Cell formation occurs in the bone marrow, then, with the help of the bloodstream, monocytes are carried to tissues, where they finally mature and become macrophages.

The largest number of macrophages is observed in the blood, liver, spleen, lymph nodes, lung alveoli, and bone marrow.

Normal: 3% - 11% of the total leukocyte blood cell count.

An increase in the level of monocytes is called monocytosis, a decrease is called monopenia.

Norms of monocytes in the blood of children depending on age.

Lymphocytes are the main cells in the body's immune defense, providing humoral (production of antibodies) and cellular (fighting foreign cells) immunity.

Norm: in children – 50%.

Eosinophils are a type of leukocyte cells related to microphages, capable of phagocytosis - absorbing small foreign cells and particles.

Red blood cells in the body are called erythrocytes; they occupy about a quarter of all cells in the human body. The main function is to transport oxygen molecules from the lungs to all tissues and organs and carbon dioxide in the opposite direction.

Norm of red blood cells: up to 6 million per 1 mm³ - in children.

Blood test for monocyte content

The cell level is measured as a percentage of the total white blood cell count and is called the relative monocyte ratio.

Regardless of age and gender, the normal indicator is considered to be 3% - 11% monocyte content of the total number of leukocytes.

Some techniques are aimed at counting the total number of monocytes in the blood - the absolute number of cells.

The norm of monocytes per liter of blood: 0.05 – 1.1 x 109/l. – children under 12 years old, 0 – 0.08 x 109/l. – over 12 years old.

Why is the monocyte count increased?

Most often, monocytosis in a child can be observed with infectious diseases (syphilis, brucellosis, toxoplasmosis, infectious mononucleosis). The level of monocytes increases due to severe infectious processes(sepsis, subacute endocarditis, tuberculosis), with the development of fungal infections (candidiasis) and cancer, as well as as a result of fluorine or tetrochloroethane poisoning.

during the acute phase of infections: rubella, measles, mononucleosis, influenza, diphtheria, as well as initial stage recovery;
tuberculosis;
lymphoma (tumor growth);
leukemia (blood cancer);
one of the many signs of lupus erythematosus;
toxoplasmosis, malaria.

The level of immune cells can be brought back to normal only by identifying the disease that caused the increase in monocytes and treating it.

Monocytes and eosinophils are increased

Lymphocytes are the main ones immune cells, thanks to which the body’s protective reaction to infectious diseases persists for life: a person can only get measles, rubella once, chicken pox, mononucleosis.

Decreased lymphocytes and increased monocytes can occur for two reasons:

in diseases (tuberculosis, lupus erythematosus, lymphogranulomatosis) when lymphocytes died in the fight against foreign agents, and blood was withdrawn for analysis when new cells had not yet formed;
- in case of pathology of the process of formation and maturation of new lymphocytes (anemia, HIV, leukemia, chemotherapy).

ESR readings

The erythrocyte sedimentation rate is always considered together with the content of basic blood parameters. However, an elevated ESR in children may indicate the presence of infectious diseases in the body.

ESR norm indicators vary depending on age stage child.

anonymous, Female, 2 years old

Hello! We went to the garden, we got sick on December 28, snot, fever... On the 3rd day a dry cough developed, she gave syrup, licorice root, milk and honey... I called a doctor, listened, there was no wheezing, my throat was clear, she prescribed me to drink syrup and Biseptol (they drank it 3 day). On the 5th day the cough turned into a wet one, leading to vomiting at night. On the 10th day of illness, I didn’t sleep all night, my tummy hurt, in the morning the temperature rose to 37, after 10 minutes I slept.. Then during the day it rose to 37-37.2 for an hour or two. We decided to donate blood and urine. Now there is almost no snot, but there is gurgling in the nose, the cough has also gone away, but sometimes the voice is hoarse until I ask her to clear her throat.. Tell me what elevated platelets, monocytes and ESR mean; result; reference values off. Total leukocyte count (wbc), 10^9/l 13.16 5.50 - 15.50 -(--O)- total red blood cell count (rbc), 10^12/l 4.66 3.80 - 4.80 -(--O)- hemoglobin (hb) , g/l 130 110.00 - 140.00 -(-O-)- hematocrit (ht), % 37.4 32.00 - 40.00 -(--O)- average hemoglobin content in an erythrocyte (mch), pg 27.9 22.00 - 30.00 -(-- O) - average erythrocyte volume (mcv), fl 80.3 73.00 - 85.00 -(-O-) - average hemoglobin concentration in erythrocytes (mchc), g/l 348 320.00 - 380.00 -(-O-)- platelets (plt), 10^9/l 393 150.00 - 350.00 -(---)O distribution of erythrocytes by volume (rdw cv), % 13.1 12.0 - 14.5 -(-O-)- blast cells, % 0 0.00 -(-O-)- promyelocytes, % 0 0.00 -(-O-)- myelocytes, % 0 0.00 -(-O-)- metamyelocytes, % 0 0.00 -(-O-)- band neutrophils, % 1 1.00 - 5.00 -(O--) - segmented neutrophils, % 43 32.00 - 55.00 -(-O-)- monocytes, % 13 3.00 - 9.00 -(---)O basophils, % 0 0.00 - 1.00 Parameter result reference values off. Eosinophils, % 4 1.00 - 6.00 -(-O-)- lymphocytes, % 39 33.00 - 55.00 -(O--)- plasma cells, % 0 children of the first two weeks: 0 - 0.5%; For children and adults: 0%. Erythrocyte sedimentation rate (ESR), mm/hour 25 0.00 - 10.00 -(---)O absolute content of neutrophils, 10^9/l 5.79 1.10 - 5.80 -(--O)- absolute content of eosinophils, 10^9/l 0.53 0.07 - 0.88 -(-O-)- absolute content of basophils, 10^9/l 0.00 0.00 - 0.05 -(O--)- absolute content of monocytes, 10^9/l 1.71 0.37 - 1.26 -(---) O absolute content of lymphocytes, 10^9/l 5.13 1.60 - 7.10 Urinalysis: parameter result reference values color straw yellow; yellow transparency slightly cloudy transparent relative density 1.026 Newborns: 1.002 - 1.020; Children: 1.002 - 1.030; Adults: 1.010 - 1.025 Ph 5.0 Prematures: 4. 8 - 5.6; Newborns: 5.5 - 6.0; Breastfeeding babies: 7.0 - 7.8; Infants on artificial feeding: 5.5 - 7.0; Children from one year old and adults: 5.5 - 7.0 Protein (g/l) 0.1 0.00 - 0.14 Glucose (mmol/l) 0 0.00 - 0.80 Ketone bodies negative negative reaction to blood negative negative bilirubin negative negative urobilinoids normal normal cells squamous epithelium 0-1 in the field of view 0 - 4 in the field of view there are no transitional epithelial cells 0 - 1 in the preparation there are no renal epithelial cells there are no leukocytes (units in the visual field) 1-3 0 - 3 in the field of view parameter result reference values erythrocytes changed (units in the field of view) not detected not detected red blood cells unchanged (units in the field of view) not detected 0 - 1 in the field of view granular cylinders (units in the field of view) not detected not detected hyaline cylinders (units in the field of view n/zr) not found not found epithelial casts (units in n/zr) not found not found waxy casts (units in n/zr) not found not found erythrocyte casts (units in n/zr) not found not detected leukocyte casts (units in p/zr) not found not detected pigment casts (units in p/zr) not found not found mucus insignificant quantity not found bacteria not found not found budding yeast cells not found not found yeast cells with no pseudomycelium detected no salt detected no salt detected thank you! I hope for early answer.

Hello! The platelet level can safely be considered normal. Different laboratories give different reference values and up to 450 there is no need to worry. These formed elements take part in blood clotting. Monocytes can be called the “janitors” of our body in another way, and they naturally increase after illness. Erythrocyte sedimentation rate is an indicator of inflammation. In your case, such a reaction may be associated with a complicated course of acute respiratory viral infection. It is necessary to examine the child to exclude the presence of foci of bacterial inflammation that may become chronic, to monitor and interpret a blood test in a dimantic, to decide on the prescription of first-line antibiotics (semi-synthetic pinicillins).

anonymously

Thanks for the answer! Today we had an appointment with the pediatrician, listened, there is no wheezing, the throat is not red, the sniffles are a little clear, the child’s condition is good, he sleeps, eats well, but because of ESR 25, he prescribed sumamed for 5 days. I’m at a loss, we never took antibiotics, and we only coughed once, we were always treated with folk remedies. Tell me, is it possible to wait until the appointment and repeat the blood test at the end of the week? The temperature during the entire illness was only 2 days at the very beginning, then in the middle of the illness for one day, and then for a couple of hours 37.2.

Do not worry! Of course, to cancel the appointment, it is better to see the child, but it is also not worth treating the analysis. And sumamed is not the antibiotic you should start with if you have never taken it before. Unprotected semi-synthetic penicillins are prescribed (amoxicillin in a dose calculated per kg of the child’s weight, 20 mg/kg in 3 doses, 7 days). Now in the global medical community there is a concept of delayed antibiotic prescription. Based on what you described, we can recommend blood control. When you get the result, write and be healthy!