Cholisal analogues are cheaper. How to replace Cholisal, we are considering gel analogues. Special points of therapy

Cholisal is a drug with a combined effect. It has analgesic, antimicrobial and anti-inflammatory effects. People with weak immune system often have to deal with various inflammations V oral cavity associated with pathogenic bacteria. In such cases, Cholisal or its cheap analogue is used.

Instructions for use and composition

Active component of the gel - Choline salicylate, has anti-inflammatory and analgesic effects. The substance reduces the activity of neutrophils and macrophages, cyclooxygenase and prevents the synthesis of prostaglandins. The components of the composition do not lose their medicinal properties with exposure to an alkaline environment, and also have antifungal and antimicrobial effects. Cholisal is quickly absorbed through the mucous membrane.

An additional component of the gel, tsetalkonium chloride, destroys gram-negative and gram-positive microorganisms, viruses and fungi. Propyloxybenzoate has an antibacterial effect. Due to its viscous consistency, Cholisal is not washed off from the surface by saliva.

Analgesic effect starts to appear after 4 minutes after using the medicine. The drug does not contain sugar and is well tolerated by patients.

To achieve an analgesic effect, Cholisal should be used 2 times a day. The gel is best applied after meals and before bed. For a person over 18 years of age, the dosage is 1 cm of gel, for children - 0.5 cm. The medicine should be rubbed with light circular movements into the affected area. If the composition is part complex treatment periodontal diseases, then the gel is used up to 2 times a day. After using the medicine, you need to avoid eating for 30 minutes. The duration of use of Cholisal gel is determined by the doctor, based on the patient’s indicators.

Instructions for use for periodontal disease

Cholisal is very effective in treating this disease. At the first stage, the doctor removes the cause of the disease and tartar. And only then is Cholisal applied, both externally and internally inner part gums. To increase the effectiveness of treatment, the gel must be delivered exactly into the gum pocket. Composition required apply 3 times a day.

Instructions for use for gingivitis

Cholisal effectively counteracts gum inflammation. But before using the medicine, you need to get rid of tartar. If you ignore the cause of the disease, it can lead to tooth decay.

For gingivitis, Cholisal is applied 2 times a day. In order for the composition to stick better to the surface, it needs to be dried using a gauze pad.

Instructions for use during teething

Cholisal can be used for children who have reached the age of 1 year. The composition has a fruity smell, which does not cause rejection in the baby. The medicine helps well with teething, but it should not be used frequently. You must strictly follow the dosages indicated in the instructions.

Cholistal does not contain lidocaine, to which some babies have an allergic reaction. Before using the composition, you need to pre-treat the oral cavity. Take a glass boiled water and add a little soda. Take a sterile cotton swab, dip it and wipe your gums. After the procedure, you can apply Cholisal. Judging by the reviews, most people use the drug for this very purpose.

Side effects and contraindications

Cholisal should not be used:

At hypersensitivity to one of the components.
During pregnancy.
Children should be given the drug only after consulting a doctor.

At the first signs of an allergy to Cholisal, the composition must be washed off and consult a doctor. Slight burning sensation, for 40 seconds, is not a side effect. And some people, judging by the reviews, perceive this as a manifestation of an allergic reaction. The use of the composition together with painkillers, antipyretic and anti-inflammatory drugs enhances their effect. Side effects from the drug may occur due to its long-term use or exceeding the dosage. You must carefully study the instructions before use.

Analogs

Judging by the reviews, due to the high price of Cholisal (300 rubles per 10 grams), many people are looking for medications with similar effects, but cheaper. Choosing the right analogue is not so easy, because you need to take into account many factors. This is especially true when used together with other drugs. You can make the process much easier by reading reviews on the Internet.

Voqara

This homeopathic medicine which has a complex effect. It is prescribed to patients suffering from tonsillitis, gingivitis, and stomatitis. The composition of the drug includes: sage, laccone, belladonna, snake venom. The medicine can be used from 12 years of age. Thanks to its natural ingredients, Vokara has no contraindications. Price - 200 rubles.

Dentamet gel

The medicine is widely used in dentistry to treat the following diseases: periodontitis, gingivitis, stomatitis. The drug contains: metronidazole - which destroys pathogenic microorganisms; chlorhexidine - has disinfectant properties. The drug has no age limit, but children and pregnant women should take it only after consulting a doctor. There are many positive reviews on the Internet. Price - 110 rubles.

Anti-Angin Formula

Very effective analogue Cholisala is prescribed for inflammation of the pharynx and oral cavity. Available in the form of spray and tablets. The composition of the medicine includes: tetracaine, ascorbic acid, chlorhexidine. The first component has an analgesic effect. Ascorbic acid, helps reduce swelling and stimulates regeneration. Chlorhexidine destroys most gram-negative and gram-positive microorganisms. The medicine can be used from 5 years of age. Cannot be used during pregnancy and breastfeeding. Price - 110 rubles.

Metrogil Denta

The gel is a popular analogue of Cholisal. According to the instructions, it contains the same components that have anti-inflammatory and analgesic effects. In the absence of allergic reactions to the components, the gel is prescribed from 6 years of age. Price - 205 rubles.

Kamistad

The drug has analgesic and anti-inflammatory effects. The main components of the gel are lidocaine and chamomile tincture. Thanks to this, the gel can be used starting from 3 months. This greatly facilitates the process of teething in children. A large number of positive reviews on sites for mothers. Price - 250 rubles.

Faringosept

Another popular analogue of Cholisal, which is used in ENT practice and dentistry. The drug is prescribed for infections of the oral cavity and larynx, stomatitis, tonsillitis, gingivitis. The medicine begins to be used from 3 years of age. There aren't many reviews. Price - 145 rubles.

For stomatitis, inflammation of the gums and tongue tissues, ulcers and irritation in the oral cavity, during the emergence of new teeth, use Cholisal gel. Analogues of the drug contain a complex of active substances with analgesic and antimicrobial effects, but the degree of influence on problem areas differs. Doctors recommend reading information about Cholisal substitutes and learning the rules for selecting the optimal types of gels and dental pastes for topical use.

Composition of the drug Cholisal

The combined drug gives an active antimicrobial and anti-inflammatory effect. also reduces pain in affected areas when dental diseases of various etiologies.

Dental gel Valeant LLC Holisal

The local remedy contains components with antiseptic, analgesic and anti-inflammatory effects. Cholisal gel is often prescribed by dentists for active tissue healing and suppressing the growth of pathogenic microorganisms.

The composition is allowed to be used from the age of three: a slight analgesic effect helps children and adults endure pain.

Active substance

The combined effect provides:

Choline salicylate. The substance reduces inflammation, reduces pain in problem areas of the oral cavity;
cetalkonium chloride. A broad-spectrum antiseptic inhibits the activity of fungi, bacteria, and viruses;
methylparaben and propylparaben - additional substances of the dental gel that activate the antibacterial effect;
Anise oil is a natural component with a cooling effect.

Inexpensive analogues

Finding a substitute for Cholisal dental gel at a low price is quite difficult. Most drugs belong to the high and medium price categories. Some items have an acceptable price, but when purchasing, a nuance appears such as the volume of the medicine: a tube may contain only 8 g of gel.

Russian made

Effective names:

. The dental gel contains a complex of bactericidal substances: metronidazole + chlorhexidine, exhibits a pronounced bactericidal and antimicrobial effect, but the analgesic effect is practically absent. The volume of the composition in a soft plastic tube is 20 g, the average price is 250 rubles. Good value prices and therapeutic effects. Dental gel is allowed from 14 years of age. The drug is produced by Johnson and Johnson, which has subsidiaries in Russia.
- a proven, safe and effective combination drug for use in dental practice. Active ingredients: chamomile extract (preparation for adults) or polidocanol (gel for children). Pleasant taste of honey and mint, wound healing, anti-inflammatory effect. The composition accelerates tissue regeneration, soothes gums and permanent teeth. Apply the composition two or three times a day. Average cost - 260 rubles, volume - 10 g.
. Concentrated solution for rinsing the mouth for many types of dental diseases. Active antimicrobial, disinfectant, antispasmodic and hemostatic effect. The dark brown liquid with a specific odor contains extracts of chamomile, yarrow, marigold and ethyl alcohol. The volume of the solution is from 25 to 100 ml. The drug is produced by several Russian companies: Evalar, Vifitech, Tver and Moscow pharmaceutical factories. The cost of antiseptic is no more than 50 rubles.

Foreign analogues

Preparations for the treatment of dental diseases:

. Paste for topical use. The dental adhesive composition is easy to fix on the gums and mucous membranes due to its optimal consistency. Active components: solcoseryl - deproteinized hydrolysate from the blood of dairy calves and polidocanol 600 - a safe, effective local anesthetic. The paste forms a protective layer on problem area, accelerates tissue healing, quickly relieves pain (3-5 minutes). Analgesic effect lasts up to five hours. Wide range applications, low risk adverse reactions. The drug is produced by a pharmaceutical company from Switzerland, the estimated cost is 470 rubles.
Kalgel. A combined drug with bactericidal and local anesthetic effects. Dental gel is effective in treating not only bacterial but also fungal infections. Active substances: antiseptic cetylpyridinium chloride and powerful local anesthetic - lidocaine hydrochloride. The volume of the product is 10 g, the average price is 340 rubles. Allowed for use by children over 3 years of age.

In pharmacies you can find an analogue of Cholisal - Mundizal gel. The cost of the drug is 350 rubles, but the volume of the product in the tube is almost 2 times less: only 8 g.

For children

When prescribing dental gel, the doctor takes into account the age of the small patient.

Necessity of purchase local drugs for the treatment of the oral cavity occurs more often.

In most cases, they occur after 5-6 years. For this reason, for children, manufacturers offer formulations with a gel-like consistency with an analgesic, cooling, and soothing effect.

Medicines for children contain extracts medicinal plants and safe anesthetics (polidocanol).

It is important to choose a drug marked Baby: adult brands contain lidocaine, which provokes active salivation, which is dangerous for infants (a child can choke while lying on his back).

Effective dental compositions for children:

Baby doctor.
Dentinox.
Kalgel.
Pansoral.
Dentol baby.

Price

The price of dental gels is quite high.

It is not easy to find analogues of Cholisal at an affordable price.

Purchasing most items will cost from 250 to 460 rubles; the volume of product in a tube is small - from 8 to 20 g.

One hundred and teething.

Despite the high cost of combined formulations, it is difficult to replace them with other types of dental products. Paste and gel are the optimal form of preparations for long-term effects on inflamed areas. It is no coincidence that doctors advise rinsing your mouth with an antiseptic and treating the affected areas after a certain period. local remedy thick consistency.

How to choose

Most dental gels can be purchased without a prescription. If it is not possible to consult a doctor, it is important to figure out which product to choose for treating cracks or painful areas during teething.

When purchasing a gel you need to consider:

type of disease, area of localization of problem areas. Before visiting a doctor, you can find a lot useful information in the Internet;
child's age: many dental preparations are allowed to be used from 6-12 years;
composition of the drug, degree of effect on the oral cavity, type of effect. Some compositions exhibit a pronounced analgesic effect, but the antimicrobial activity is weak, others have a detrimental effect on pathogenic microorganisms, but do not completely eliminate discomfort in the mouth. There are several combination formulations;
risk of possible side effects, the likelihood of allergic reactions due to excessive sensitivity of the body;
contraindications (absolute and relative);
volume of product in a tube or bottle. This point is important when comparing the cost of drugs;

Cholisal (choline salicylate + cetalkonium chloride) is a combination drug from the Polish pharmaceutical company Jelfa, which has antibacterial, antimicrobial and analgesic effects and is used in dental practice. Available in gel form. Quickly stops painful sensations and destroys pathogenic bacteria without causing negative influence at the same time on saprophytic microflora. The complex effect of the drug is achieved through the combination of choline salicylate and tsetalkonium chloride. The first of the two substances belongs to non-steroidal anti-inflammatory drugs that suppress the release of mediators of pain and inflammatory reactions. The gel dosage form allows choline salicylate to be absorbed quickly and long time remain in the inflammatory focus. Cetalkonium chloride is a disinfectant and antimicrobial agent that extends its effect to staphylococci, streptococci, coli, Pseudomonas, Proteus, Bacteroides, Peptotreptococcus, Klebsiella, Clostridium, Candida and virus herpes simplex. Peculiarities dosage form provide good penetration of active substances, and auxiliary ingredients potentiate the antimicrobial effect. The drug does not contain antibiotics, which can suppress both pathogenic and saprophytic microflora at the same time, thereby disturbing the bacterial balance in the oral cavity. Thanks to its disinfecting properties, the drug prevents secondary infections of the oral cavity. The analgesic effect of Cholisal develops within 3 minutes after application of the gel. The duration of action of the drug can reach 8 hours. A four-day course of medication is sufficient for complete healing of erosive lesions of the oral mucosa that arose as a result of wearing braces or dentures.

Five days is enough to eliminate increased bleeding and eliminate unpleasant odor for periodontal diseases. The small size of the tube ensures practicality and ergonomics. The drug is widely used in pediatric practice in patients over 1 year of age. The essential anise oil included in Cholisal improves organoleptic characteristics and enhances the anti-inflammatory and disinfecting effect (the aromatic ester anethole is “responsible” for this). A single dose of the drug is a gel “sausage” 1 cm long (for children – 0.5 cm). The gel is rubbed into the inflamed area with soft and light movements. Frequency of use – 1-2 times a day. Before using the drug, you must brush your teeth. You should refrain from eating or rinsing your mouth for half an hour after the procedure. The duration of pharmacotherapy for periodontitis is 10-14 days (with mild form disease), 30 days (for severe). Optimal time taken - after meals and before bedtime. Cholisal is not absorbed into the systemic bloodstream, and therefore has virtually no clinically significant side effects, with the exception of allergic reactions manifested by mild itching and burning at the site of application. The only direct contraindication to the use of Cholisal is hypersensitivity to the active or auxiliary components of the drug. Pregnant and lactating women may take the drug under medical supervision. Cholisal does not contain sugar and can be used in people suffering from diabetes mellitus. Cases of drug dosage were not recorded.

Pharmacology

Combined preparation for local use in dentistry with antimicrobial, anti-inflammatory and analgesic effects.

When applied topically, choline salicylate is quickly absorbed by the oral mucosa, providing local analgesic, anti-inflammatory and antipyretic effects. It inhibits the activity of COX, the functions of macrophages and neutrophils, the production of interleukin-1 and inhibits the synthesis of prostaglandins. It also has antimicrobial and antifungal effect in acidic and alkaline environments.

Cetalkonium chloride is an antiseptic that acts on bacteria, fungi and viruses.

The gel ethanol-containing adhesive base ensures rapid development of the effect and retains the active substances on the mucous membrane for a long time.

The analgesic effect occurs within 2-3 minutes, while its duration is 2-8 hours.

Pharmacokinetics

When applied to mucous membranes, it is well absorbed.

Release form

Dental gel in the form of a colorless, transparent, homogeneous mass with the smell of anise oil.

Excipients: hyaetellose - 20 mg, methyl parahydroxybenzoate - 1.5 mg, propyl parahydroxybenzoate - 0.8 mg, glycerol - 50 mg, anise seed oil - 1.61 mg, ethanol 96% - 390 mg, water - up to 1000 mg.

10 g - aluminum tubes (1) - cardboard packs.

Dosage

Cholisal ® is used topically 2-3 times a day before meals (for pain relief) or after meals and before bed. A strip of gel 1 cm long for adults and 0.5 cm for children is squeezed onto a clean finger and rubbed with light massaging movements into the affected area of the oral mucosa.

For periodontal diseases, the gel should be placed in the gum pockets or applied in the form of compresses, or gently rubbed into the gums 1-2 times a day.

Overdose

No cases of overdose have been identified.

Side effects

Local reactions: a short-term burning sensation at the site of application of the drug, which goes away on its own.

Others: allergic reactions.

Indications

For local use on the mucous membranes of the oral cavity as an analgesic and anti-inflammatory agent in the treatment of periodontal diseases, damage to the mucous membrane, diseases occurring with inflammatory reaction and pain:

stomatitis of various etiologies;
gingivitis;
periodontitis;
damage to the oral mucosa when wearing dentures;
trauma to the oral mucosa;
pain during teething in children;
cheilitis;
candidiasis of the oral mucosa;
small surgical interventions in the oral cavity;
lichen planus when localized on the oral mucosa;
damage to the oral mucosa in Stevens-Johnson syndrome (as part of complex therapy).

Contraindications

hypersensitivity to salicylates and other components of the drug.

The drug should be used with caution during pregnancy, during breastfeeding and in children under 1 year of age.

Features of application

Use during pregnancy and breastfeeding

Cholisal ® should be used with caution during pregnancy and breastfeeding.

Use in children

The drug should be used with caution in children under 1 year of age.

special instructions

When the first signs of a side effect appear, the patient should immediately contact their doctor.

The drug should be used for topical use only.

The drug does not contain sugar.

Impact on the ability to drive vehicles and operate machinery

The drug does not limit psychophysical activity or the ability to control vehicles and maintenance of moving mechanisms.

Cholisal has gained a reputation as an effective remedy that can solve oral problems for all family members, young and old. The drug is sold without a doctor's prescription and this drug is not in short supply in the pharmacy chain. But for a number of reasons, it may be necessary to replace Cholisal with an analogue, for example, if there is a contraindication to its use, an allergic reaction to a component of the composition. For some, the cost of the gel is high, which encourages them to search for more available funds. In this article we will figure out what can replace Cholisal.

2 style="text-align: center;"> About the drug Cholisal

The manufacturer of the product is Valeant.

Cholisal is a transparent gel that smells like anise. It is used for diseases of the oral cavity, the symptoms of which are inflammation and pain. Such diseases include:

– this is an unpleasant disease of the gums, accompanied by bleeding, soreness, and swelling;
– this is a disease that appears when gingivitis worsens;
: its symptoms are plaque, ulcers, painful erosions on the mucous membrane;
cheilitis, popularly called “jams”;
lichen planus of the oral mucosa, manifested by an itchy rash;
mucosal injuries, which may be caused by mechanical damage when wearing

Let's look at analogues of the product in composition and active ingredients, release form and pharmacological action.

2 style="text-align: center;"> Analogues of Cholisal according to the active substance

The active components of Cholisal are:

choline salicylate – relieves pain, reduces inflammation, fever;
Cetalkonium chloride is an antiseptic.

There are 2 more products with the same components - Mundizal and Pansoral. Both drugs are available in gel form; the list of indications includes conditions and diseases similar to Cholisal. Let's take a closer look.

3 style="text-align: center;">Mundizal gel

Mundizal is produced by the Austrian pharmaceutical company Mundipharma. Due to the choline salicylate included in the composition, Mundizal has an anti-inflammatory and analgesic effect at the site of application of the gel. Literally a couple of minutes after application, the patient feels a significant reduction in pain.

Mundizal is a less popular drug than Cholisal.

The drug entered the market not so long ago and is not yet as popular as Cholisal. The gel is produced in tubes of 8 grams, that is, the volume is almost half that of the Cholisal gel. But the prices for the drugs are almost the same, so Mundizal cannot be considered as a cheaper analogue. Its purchase is advisable only if Cholisal is not available in the pharmacy and there is a need to buy the medicine as quickly as possible. The cost of a 15 gram tube of Cholisal is about 450 rubles, Mundizal will cost about 380 rubles.

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An analogue of Cholisal dental gel with more affordable price is considered a drug under trade name Pansoral. The medicine is produced by the French company Pierre Fabre Medicament. A 15 gram package of Pansoral gel costs about 280 rubles.

Cholisal oral gel is not recommended for use by children under one year of age. This is due to the anise oil included in the composition. It increases saliva production, which can cause discomfort in the baby. Pansoral, unlike Cholisal, can be used for infants. Auxiliary components of the drug are chamomile extract, marshmallow, saffron, Irish moss. It can be used when the baby reaches 4 months of age; many children begin to experience symptoms during this period.

Pansoral is an analogue of Cholisal in terms of the active substance.

Pansoral gel has a sweetish taste, so children readily agree to use it. Sodium saccharin is included as a sweetener; sweeteners are produced on the basis of this substance.

Similar to Cholisal for gums, Pansoral is used exclusively topically. It is applied to damaged mucous membranes or swollen gums before pecking a tooth. You cannot use the gel more than 4 times a day.

2 style="text-align: center;"> Analogues of Cholisal according to indications

To eliminate pain during teething and if the child is allergic to Cholisal, you can try replacing it with Dentol. In addition to gels, you can use solution, suppositories, tablets.

As already mentioned, Cholisal is prescribed to adult patients for diseases of the oral cavity accompanied by pain and inflammation. Dental gels, rinsing solutions, extracts, preparations for internal use There are many, the purpose of which is to eliminate periodontal diseases and oral mucosa.

For example, for stomatitis, bleeding gums and their soreness, you can rinse your mouth aqueous solution or . This herbal preparations, with virtually no side effects. You can also cope with gingivitis and stomatitis with the help of homeopathic medicine Vokara, which contains snake venom, belladonna and sage. However, the effectiveness of homeopathy remains a controversial issue for many.

If you are looking for alternatives with a release form and method of application similar to Cholisal, then there are many such options. These are Asepta, Kamistad, Solcoseryl, Metrogyl Denta, Elugel, Dentamet, Parodium... The list can be continued for a very long time. Let's look at the most effective of them.

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– one of the most frequently prescribed gels by dentists. This popularity is due to the fact that Metrogyl Denta has been on the market longer than other drugs. However, in last years The range of medicines, in particular for the treatment of oral diseases, has expanded significantly. On this moment Metrogyl Dent cannot be called the most effective remedy.

The product does not have an analgesic effect, unlike Cholisal.

Metrogil contains:

metronidazole, which has antimicrobial activity;
chlorhexidine, which has an antiseptic effect.

When choosing which is better, Metrogyl or Cholisal, many experts advise giving preference to the second drug. The fact is that the main action of Metrogyl Dent is aimed at eliminating harmful microorganisms in the oral cavity. This is a good antimicrobial gel, but it is not able to reduce painful sensations, caused by the same stomatitis or gingivitis, as Cholisal does. The active components of Cholisal affect neurotransmitters in tissues, providing an anti-inflammatory effect and reducing pain.

However, Metrogyl has some advantages. For many, the deciding factor when choosing a gum gel will be the price. Metrogil has it available. A 20 gram tube of product can be purchased for about 200 rubles.

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And for diseases of the oral mucosa, and for painful teething teeth in children can be used. This drug is produced by the same company as Cholisal gel - Valeant.

Solcoseryl is a unique medicine. Its active ingredient is calf blood dialysate. During the production of the drug, the blood of calves is purified from proteins and allergens using a special technology. This component promotes tissue renewal and rapid healing.

Solcoseryl and Cholisal are produced by the same company - Valeant.

Polidocanol is added to the composition as an analgesic component. To better fix the paste on the mucous membrane and prevent it from being washed away by saliva, the composition includes gelling components and thickeners. Solcoseryl paste is called adhesive, which indicates its ability to reliably adhere to the oral mucosa and surface of the gums.

As already noted, Cholisal for children infancy does not apply. But Solcoseryl paste has no restrictions on its use in infants. It can be used to reduce pain during the eruption of the very first incisors.

When choosing a gel for your baby between Cholisal or Solcoseryl, your pediatrician should advise which will be better specifically for your baby. Both drugs can cause allergic reactions such as rash. Solcoseryl is able to influence taste analyzers, distorting the sensations when eating for some time after applying the paste. Cholisal has a characteristic anise aroma, which may also not be to your baby’s liking.

If we talk about the effectiveness of using medications to treat diseases of the gums and oral mucosa in adults, then these drugs are almost equivalent. Positive reviews indicate a rapid therapeutic effect when using both Solcoseryl and Cholisal. For example, both remedies can cure ulcers on the mucous membrane in about 3 days.

The volume of a tube of Solcoseryl paste is tiny, about 5 grams, and it costs around 400 rubles.

3 style="text-align: center;">Acepta

For dental diseases, including common periodontitis and gingivitis, effective assistance Asepta gel based on propolis extract can provide relief. This natural component is known for its anti-inflammatory and antimicrobial properties. The gel can also be used for prevention; it perfectly strengthens the gums and prevents their bleeding. For the purpose of prevention, Asepta gel is used up to 3 times a year in weekly courses. A ten-gram tube of gel will cost about 200 rubles.

If you want to find a “substitute” for Cholisal, there should be no problems. Range pharmaceutical drugs today is extensive, and it has both medicines with exactly the same active ingredient, as well as medications with similar indications for use. But self-medication is a dangerous activity! Only a doctor should prescribe any medications!

Gel Cholisal is effective remedy, which has pronounced analgesic, antibacterial and anti-inflammatory properties. The medication is actively used in the treatment dental pathologies and is one of the most sought after products in this area. The use of Cholisal is possible only as prescribed by a doctor. Independent dosage calculation and uncontrolled therapy can lead to the development of various negative consequences. However, even extremely high doses the drugs do not pose a great danger to the patient’s body, which is a significant advantage of using the medication.

Dosage form

Cholisal is produced in the form of a homogeneous mass that does not have a characteristic shade. The smell of the gel resembles the aroma of anise oil.

The medicine for the oral cavity is produced in 10 grams per tube.

Description and composition

The medication Cholisal contains the following active substances:

choline salicylate;
cetalkonium chloride.

One gram of gel contains 87.1 mg of the first active substance and 100 mcg of the second.

Among the auxiliary components are:

hydroxyethylcellulose (HEC);
glycerol;
methyl hydroxybenzoate;
propyl hydroxybenzoate;
anise oil;
ethanol;
water.

Pharmacological group

The drug belongs to a group of drugs that have analgesic, antimicrobial and anti-inflammatory effects. Cholisal is used for topical use in dentistry. Distinctive feature means that Cholisal undergoes extremely rapid absorption. This is explained local application in the oral cavity. High level absorption occurs due to application of the medication directly to the mucous membrane.

The drug stops the activity of cyclooxygenase, the formation of interleukin-1, inhibits the functionality of neutrophils and macrophages, and also significantly reduces the level of prostaglandin synthesis. Being in an alkaline environment or in an environment with increased acidity, the product has pronounced antipyretic and antifungal effects.

Cetalkonium chloride exhibits an effective antiseptic effect against many viruses, bacterial microorganisms and fungi.

The gel base containing ethyl alcohol allows the product to retain the active elements on the surface of the mucous membranes for a long time, ensuring the fastest possible achievement of the therapeutic effect.

Pain relief begins 2-4 minutes after the initial application of the gel. The duration of the effect is on average from 2 to 8 hours.

Cholisal gel does not contain sugar and does not have a local irritating effect, which is a significant advantage in comparison with other similar products.

Indications for use

The drug Cholisal is used primarily in dental practice. The medication is applied to the mucous membranes of the growth cavity to provide a rapid anti-inflammatory, antiseptic and analgesic effect.

for adults

Indications for the therapeutic use of Cholisal in adult patients are:

gingivitis;
injuries to the mucous membranes of the mouth during the use of dentures or under other circumstances;
cheilosis (cheilitis);
red flat;
surgical procedures of a dental nature;
periodontitis;
oral candidiasis;
of various origins;
exudative erythema multiforme(as one of the medications in complex therapy).

for children

In addition to all of the above, the basis for the appointment medicinal use Cholisal gel for children is pain syndrome during teething. Children under 1 year of age should take the drug under the strict supervision of a pediatrician.

Indications for the use of Cholisal gel during lactation and pregnancy are the same conditions as for ordinary adult patients. Before use you should go through full diagnostics body of a pregnant woman or nursing patient to identify potential danger for the health of the child.

Contraindications

There are absolute prohibitions on using Cholisal gel in medicinal purposes include:

hypersensitivity to salicylic acid preparations;
increased susceptibility to other elements of the Cholisal composition.

Carefully:

pregnancy;
child's age up to 1 year;
breastfeeding period.

Applications and dosages

The dosage and time of use should be agreed with your pediatrician, family doctor or dentist.

To apply Cholisal gel to the affected area, squeeze the tube onto a clean finger in the amount prescribed by your doctor. After this, you need to apply the gel and rub into the skin with gentle massaging movements. Right place on the mucous membrane of the oral cavity.

For periodontal pathologies, it is necessary to apply the gel directly to the gum pockets. You also need to make compresses and gently rub Cholisal gel into the gums 1 to 2 times a day.

for adults

To ensure an analgesic or other necessary effect, an adult patient must apply a 1 cm strip of gel 2 to 3 times a day before (analgesic effect) or after meals and before going to bed.

for children

The mechanism for applying the medication for children is the same as for adults, however, the amount of gel should not exceed 0.5 cm. When using the product on children, extreme caution must be taken and avoid rough and sudden movements during rubbing.

for pregnant women and during lactation

Particular care should be taken during treatment with Cholisal for pregnant patients and women undergoing breast-feeding. This is due to the fact that there is very little evidence denying the danger of using Cholisal during such periods. During therapy, it is recommended to undergo tests and diagnostic examinations as often as possible. Based on the examination results, the specialist will be able to adequately formulate the method of administration and dosage of the medication.

Side effects

The drug Cholisal is quite well tolerated by patients of all ages. Minor side effects include:

a sharply appearing and quickly disappearing burning sensation in the area where the gel is applied;
allergic manifestations of various types.

The above side effects are observed extremely rarely and do not pose a critical danger to the life and health of the patient. But, despite this, at the slightest sign of negative manifestations, you should immediately contact a specialist.

Interaction with other drugs

During joint application Cholisal gel with other anti-inflammatory, analgesic, antipyretic medications shows a significant increase in their therapeutic properties. However, this effect occurs only when taking dosages of the drug several times higher than the average daily dose.

special instructions

The medication is sold in pharmacies as an over-the-counter substance.

The gel should be taken only as an external remedy.

Cholisal does not affect nervous system patients and does not limit the ability to drive vehicles, as well as work with high-precision mechanisms.

Extreme caution must be exercised when treating children under 1 year of age.

Overdose

Intoxication with Cholisal gel is almost impossible due to low level systemic absorption of elements included in medicinal composition facilities.

Despite this, you should avoid increased dosages drugs while taking other analgesic or anti-inflammatory medications, in order to avoid the manifestation of negative symptoms.

Storage conditions

The medication should not be kept cold or frozen.

The optimal storage temperature is 25 degrees.

Store in a dark place, out of reach of children.

Shelf life – 3 years from the date of issue.

Analogs

Instead of Cholisal, the following medications can be used:

Mundizal is a German drug that contains choline salicylate. The medicine is produced in the form of a gel, which is used in dentistry. Mundizal is contraindicated for children under one year of age, pregnant women, and during lactation.
Dologel ST is a combined Indian medicine that is available in the form of a dental gel. It relieves inflammation, has an antibacterial and local anesthetic effect. The drug can only be used in adults; it is contraindicated in pregnant and lactating women.
- a combination preparation that also contains chamomile as active ingredients. It is produced in the form of a dental gel, which has an antiseptic and local anesthetic effect. It can be used by patients over 12 years of age, except pregnant and lactating women.
belongs to Cholisal substitutes according to the clinical and pharmacological group. The drug is produced in the form of a dental gel, which is used in children's practice during teething.

Drug price

The cost of Kholisal is on average 349 rubles. Prices range from 122 to 664 rubles.