Ruzam composition. Ruzam: action against allergies, instructions for use, patient opinion. Contraindications to the use of injection solution


To combat allergy symptoms, antihistamines are often used in tablets, spray, drops or gel form. Injections are used much less frequently. Injections are necessary for acute forms allergies, as well as for prevention.

One of the effective medicines, which are presented on the market, is considered to be Ruzam. Today it has no analogues. Using it, you can effectively stop the development of many types of allergic reactions.

Ruzam-M LLC produces Ruzam injections. The drug is both an antiallergic and an anti-inflammatory agent. Using it you can:

  • Eliminate a number of allergy symptoms and alleviate the course of the disease.
  • Block mast cell degranulation.
  • Reduce the number of eosinophils in places where the inflammatory process occurs.
  • Reduce swelling in the mucous membranes of the nose and respiratory organs.
  • Reduce skin swelling.
  • Reduce the amount of immunoglobulin E in the blood if its level is higher than normal.
  • Increase the amount of secretory immunoglobulins A in the mucous membranes, because They protect the body from viruses and bacteria, and neutralize them upon penetration.
  • Reduce the accumulation of nitric oxide, which is an allergy marker, in the exhaled air flow.

Who is prescribed Ruzam for allergies?

Ruzam injections are prescribed to those who have:

Instructions for use

Ruzam injections are administered under the skin to both children and adults. The dosage for children over 6 years old is 0.2 ml, and from 4 to 6 years old – 0.1 ml. The injection should be given no more than once every 7 days. The course of treatment is 5-10 weeks. During the year, the number of courses can reach up to 4. The minimum interval between courses must be at least 20 days.

For hay fever, injections should be given 6-8 weeks before the flowering of plants that cause an allergic reaction. If respiratory infections are frequent, then Ruzam is used for prevention in spring and autumn.

It is permissible to increase the dose of the drug to 0.3 ml, if necessary. In this case, injections are administered every 5 days.

How long the treatment will take depends on the decision of the attending physician.

The drug may cause individual intolerance, and this occurs very rarely. It also practically does not cause any side effects.

Possible side effects from using the drug:

  • If there is a chronic infectious disease, the symptoms intensify.
  • With bronchitis, the cough becomes stronger.
  • The temperature rises.

It is worth noting that even the presence of one or more side effects is not a cause for concern. They only indicate the launch healing process. Therefore, you should not stop using the drug. Over time, the symptoms will completely disappear.

Ruza is contraindicated:

  • Pregnant women, as well as while breastfeeding.
  • Children under 4 years of age.
  • For acute infectious diseases and tuberculosis.
  • In case of decompensation internal organs.

Price of medicine Ruzam for allergies

The drug is sold in pharmacies strictly according to a doctor's prescription. Its cost is quite high. This fact confuses many buyers, because the drug may not help.

A package with five ampoules of 0.2 ml each costs approximately 1,690 rubles. There are even ones at a price of 2270 rubles.

For treatment to be effective, the course must be completed over several weeks. This means that you need to expect to purchase 2-3 packages of the drug.

Antiallergic agent latest generation has no analogues, acts effectively, rarely causes negative reactions.

How does Ruzam differ from other antihistamines? Instructions for use contain all necessary information about the medicine.

Compound

This unique product belongs to a modern class of drugs with active anti-inflammatory properties. Peptides are highly effective protein substances with high activity of biological components.

Ruzam contains a conditionally processed strain pathogenic microorganismStaphylococcus aureus(there is no live culture in the medicine). Under influence high temperature the peptide (adaptive protein) acquires pronounced anti-inflammatory and antiallergic properties. For this reason, successful therapy requires a minimum dosage of a modern drug.

The drug is sterile, side effects rarely occur during therapy. Unique drug not only suppresses acute reactions to irritants, but also strengthens the body's antiviral defense. The development of Russian scientists is certified, there is international recognition facilities.

Release form

The manufacturer Ruzam-M LLC offers antiallergic medicine in the form of an injection solution. Dosage – 0.2 ml. The composition is intended for subcutaneous administration. There are 5 ampoules in a cardboard package. The medicine is suitable for adults and children, the difference in use is in the daily dosage.

The second option to eliminate negative signs allergic diseases– Ruzam cream. In addition to a specially processed complex of bacteria, the product contains a bisphosphonate, olive oil, purified water, glycerin, two types of alcohol, and fragrance.

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Action

This unique drug has a positive effect on the body and reduces the signs of allergic reactions. The medicine exhibits not only antiallergic, but also active anti-inflammatory effects.

After the full course, a noticeable therapeutic effect appears. Many patients suffering from manifestations of bronchial asthma confirm that attacks occur much less frequently or stop altogether. A good result is noticeable in the treatment of allergic diseases accompanied by skin rashes.

Indications for use

An antiallergic drug is prescribed for the following diseases:

Contraindications

The biologically active agent should not be used for the following diseases and conditions:

  • active form of tuberculosis;
  • excessive sensitivity to the ingredients of the medicinal solution;
  • patient age up to four years;
  • period breastfeeding;
  • decompensated pathologies of internal organs;
  • pregnancy.

Time restrictions for injections of the drug Ruzam:

  • asthmatic attacks, a decrease in peak expiratory flow below 80% of the optimal value;
  • relapse chronic disease or the development of ARVI;
  • vaccination.

Instructions for use and dosage

  • injections of a new generation antiallergic drug are prescribed by a doctor: the drug is not sold in pharmacies without a prescription;
  • Children over 12 years of age and adult patients receive 1 injection per week, dosage – 0.2 ml. Duration of therapy – 5–10 weeks;
  • for children aged 4 to 6 years, the course of therapy is shorter - from 6 to 8 injections, dosage - half adult norm(0.1 ml);
  • At least five days must pass between injections, the maximum interval to maintain the therapeutic effect is 20 days;
  • if you are sensitive to the pollen of some plants, injections of the drug Ruzam are given 1–2 months before dangerous season with mandatory continuation of the course during the flowering of allergenic plants;
  • at severe form diseases can be combined unique remedy with traditional antihistamines and steroid compounds;
  • if there is a high risk of colds, if the patient often suffers from acute respiratory viral infections, for prevention, doctors prescribe Ruza injections in the spring and autumn, during periods of greatest decline in immunity;
  • The duration of treatment is determined by the doctor. Previous therapy does not affect the purpose and nature of use of the new allergy medicine;
  • in the absence of seasonal exacerbations, you need to take 2 or more courses of Ruzam. Interval – 3 months. With this treatment regimen, the greatest antiallergic effect is noticeable.

find out effective methods treatment of cold allergies on the face and hands.

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Side effects

Negative reactions to a drug with a unique formula appear in isolated cases. Children and adults tolerate Ruzam injections well after applying antiallergic cream negative reactions also occur rarely.

Possible side effects:

  • weakness;
  • increase in subfertile temperature;
  • increased cough;
  • increase in the volume of rashes.

Cost and analogues

Against the backdrop of the positive effects and high efficiency of the modern antiallergic composition, many patients are upset by the cost of the medicine. Ruzam is an expensive drug: a package of injection solution No. 5 costs 1,260 rubles. For optimal results, a course lasting several weeks is needed. The patient should check with the doctor about the duration of treatment in order to calculate the cost of therapy (most often 2-3 packages are needed).

The antiallergic drug has a unique formula. Today there are no exact analogues to the development of Russian scientists.

Antiallergic cream Ruzam

Features of the remedy:

  • as part of unique product– medicine Ruzam, olive oil, bisphosphonate, glycerin, flavoring, alcohol, purified water;
  • a cream with a unique composition is suitable for treating epidermis prone to irritation;
  • product for topical application for allergic reactions, inflammation, skin irritation;
  • action: soothes irritated epidermis, moisturizes, nourishes, relieves redness, reduces the volume of rashes;
  • a non-hormonal anti-inflammatory agent is applied two to three times a day to problem areas;
  • local remedy is effective for skin reactions, often accompanying diseases of allergic origin;
  • Ruzam cream is sold in pharmacies. You should not use the medicine without a prescription from an allergist;
  • The protein drug is well tolerated by most patients; negative reactions are rare. In the absence of individual sensitivity, the cream is allowed to be used in children under one year of age (from 4 months).

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Ruzam

Description current as of 03/11/2015

  • Latin name: Rusam
  • ATX code: L03AX
  • Active ingredient: Extract from the culture of a thermophilic strain of Staphylococcus aureus (Staphylococcus aureus)
  • Manufacturer: Ruzam-M (Russia)

Compound

Ruzam contains an extract from a culture of a thermophilic strain of Staphylococcus aureus (Staphylococcus aureus, strain C-2). In addition, the composition includes phenol 0.025–0.05%, 0.9% sodium chloride solution.

Release form

Pharmacies sell a solution for subcutaneous injection. The cell packaging contains 5 ampoules. The packages are placed in a cardboard box.

pharmachologic effect

Pharmacodynamics and pharmacokinetics

Ruzam is an anti-inflammatory and anti-allergic medicine. It reduces swelling of the mucous membranes and skin, increases the level of secretory Ig class A in the mucous membranes, helps reduce the number of degranulated mast cells and eosinophils at the site of inflammation, and also reduces the level of markers of allergic inflammation. The severity of allergic reactions when taken this tool decreases.

Indications for use

The medicine is used for:

Contraindications

It is forbidden to give injections when negative reaction on drug components, lactation, pregnancy, acute infection, decompensated diseases of internal organs and active tuberculosis. In addition, contraindications include age under 4 years.

Side effects

Possible exacerbation reactions: malaise, weakness, low-grade fever body, worsening cough or rash. Usually these symptoms are mild, go away on their own and do not require discontinuation of use.

Instructions for use of Ruzam (Method and dosage)

Instructions for use of Ruzam indicate that the drug is administered subcutaneously. From the age of 6 years, injections of 0.2 ml are given. For children 4-6 years old, dosages of 0.1 ml are recommended. The injection is given once every 7 days. Treatment can last from 5 to 10 weeks. There can be from 1 to 4 such courses per year. The interval between them should be at least 20 days.

In case of hay fever, injections are given 6-8 weeks before the plant begins to bloom, allergic. For the purpose of prevention with frequent respiratory infections the drug is used in spring and autumn.

Instructions for use of Ruzam indicate that, if necessary, the dose can be increased to 0.3 ml, which is administered every 5 days.

Overdose

No information on overdose was provided.

Interaction

There is no significant interaction with other agents.

Terms of sale

The medicine is sold in the pharmacy network only with a doctor's prescription.

Storage conditions

The medicine should be kept out of the reach of small children and in a dark place. The storage temperature for ampoules with the drug is 4-20°C.

Best before date

Four years. Do not use ampoules with medicine after the expiration date indicated on the packaging.

Ruzam's analogs

Currently, the drug is considered unique in its properties. Structural analogues of Ruzam with the same active ingredient are not issued.

Reviews about Ruzama

You can find the most contradictory reviews about Ruzam on the forums. However, most of them are positive. Those who have tried this remedy say that it helped with allergies. Some people with an allergic reaction to pollen note that there are still negative manifestations during the flowering period, but without severe consequences, such as asthma attacks, etc.

However, you can often find reports that one course of the drug helped, but another was ineffective. Patients sometimes report adverse reactions.

Ruzam price, where to buy

The price of Ruzam is considered very high, which many patients complain about, especially if the drug did not help them. Its cost in ampoules (0.2 ml dosage) is approximately 1,620 rubles. You can buy Ruzam in many pharmacies, but only as prescribed by a specialist.

  • Online pharmacies in Russia Russia

Pharmacy IFC

In June 2017 there were several angioedema. First it swelled upper lip With total loss voices, and spots on the hands, on the trail. same day, but already underlip, on the third, a rash broke out all over the body, on the fourth, there was swelling and a rash on the eyelids like bunches of grapes. And at this time I was in the hospital, daily injected with suprastin and hormones. I did some tests and the doctor prescribed Ruzam. I read the reviews, now I don’t know what to do or not. I’m afraid to leave Russia in the summer

Please tell me I have eczema, it’s been 1 year now, nothing helps. will the ruzas help?

Hello everyone. It helped Ruza with allergies for one year (spring), but now my immunity has decreased, I get acute respiratory infections every month and a half, and previously once a year.

Ruzam excellent remedy for allergies, as prescribed by the doctor, I injected five ampoules over five weeks, once a week. It was enough for a year, but at the end of the summer I got a runny nose again, but without exacerbations.

Admin: I want to buy an injection solution in Ufa

Maria: In fact, it feels like there are as many opinions as there are people who have migraines. I.

Inna: I also decided to take care of my health, control my diet, get more vegetables and fruits.

Nailya: The drug helps me cope with anxiety and increase concentration, but rarely does it.

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

Ruzam instructions for use, reviews

For the treatment of chronic allergies, a course of antihistamine tablets is usually prescribed; drug injections are rarely used.

An exception may be the drug Ruzam; following the schedule of its administration helps get rid of certain types of allergies and also prevents the development of a number of allergic reactions.

Clinical and pharmacological group and composition of the drug Ruzam

Ruzam belongs to the group of drugs with antiallergic effects. The main active ingredient of this medication is an extract obtained from a thermophilic strain of Staphylococcus aureus.

In addition to the drug, phenol and an injection solution, that is, 0.9% sodium chloride, were added in a minimal amount.

Ruzam is available only in ampoules with a dosage of 0.2 or 0.5 ml. The solution in ampoules is colorless or slightly colored.

pharmachologic effect

Ruzam is used as an antiallergic and anti-inflammatory medicine.

After injection of the drug, the following changes are observed:

  • Swelling of the skin and mucous membranes of the nasopharynx and respiratory system organs is reduced.
  • At the site of inflammation, the number of eosinophils decreases and the process of degranulation of mast cells is blocked.
  • The percentage of secretory immunoglobulin from class A in the mucous layers increases, and this increases their protection against infectious agents.
  • The content of total immunoglobulin from class E, which is a marker of an allergic reaction, decreases in the blood.
  • The amount of nitric oxide in the exhaled air decreases.

When treated with Ruzam, the severity of allergy symptoms decreases, and some manifestations inherent in this disease disappear completely.

Indications for use of Ruzam

The drug Ruzam must be prescribed by an allergist. The list of diseases for which Ruzam is effective includes:

  • Allergic year-round or seasonal rhinitis;
  • Bronchial asthma;
  • Urticaria;
  • Dermatitis of allergic origin;
  • Angioedema;
  • Frequently recurring respiratory infections.

Ruzam can be prescribed regardless of the total duration of the disease. It is only necessary to take into account that a greater effect will be achieved if allergy treatment is started at the first symptoms of this disease.

Main contraindications

The main contraindications to the administration of Ruzam are mostly temporary.

Treatment with this drug is delayed:

  • Throughout pregnancy and during breastfeeding.
  • For active tuberculosis.
  • Children up to 4 years old.
  • Acute infectious diseases. After respiratory infections, the course of treatment with Ruzam is usually postponed for about a month.

TO absolute contraindications may include individual intolerance to the medication and decompensated pathologies of internal organs.

Adverse reactions

It must be taken into account that adverse reactions may occur throughout treatment with Ruzam. The most common of them include:

  • General malaise, weakness and lethargy.
  • Periodic increase in body temperature to subfebrile levels.
  • Exacerbation of coughing attacks or worsening skin rashes.

Typically, all side effects are mild and disappear completely upon completion of the course of treatment.

Features of use and dosage of the drug Ruzam

The medicine Ruzam should be administered only subcutaneously, usually this is done in the upper third of the shoulder from the outside. The drug is practically painless when administered.

The dosage is selected depending on age:

  • When treating children aged 4 to 6 years, a single dose should not exceed 0.1 ml.
  • For children over six years of age and all other patients, Ruza is administered in a volume of 0.2 ml.

Allergists recommend ALLERGONIX as effective remedy from allergies. The product contains natural ingredients, living plant cells, restores metabolic processes in organism. The drug underwent clinical tests for 8 years. ALL THE DETAILS HERE.

Injection administration of the medication is usually prescribed once a week. The entire course lasts a minimum of 5 weeks, a maximum of 10 weeks.

Over the course of a year, a doctor can prescribe up to 4 courses of treatment with Ruzam, but the interval between them should not be less than 20 days.

For hay fever, injections should be prescribed approximately two months before a plant species that is allergenic to humans begins to bloom.

If Ruzam is used as an immunomodulatory agent for respiratory infections, then it is recommended to administer it in courses in the spring and autumn.

For severe allergic reactions, the dosage can be increased to 0.3 ml, and the frequency of administration reduced to once every five days.

Terms of sale and storage

The drug Ruzam can be purchased at pharmacy chains by presenting a prescription from a doctor. There are certain requirements for storing medicine.

Ruza must be stored only at temperatures between 4 and 20 degrees, that is, in the refrigerator.

The temperature regime must also be observed during transportation of the drug.

Failure to comply with storage conditions leads to a decrease in the therapeutic effect and increases the risk of allergic reactions.

If all storage conditions are met, then Ruzam perfectly retains all its properties for four years from the date of its release.

Analogues and cost of the drug Ruzam

At the moment, Ruzam is considered a drug with a unique mechanism of action, so there are no structural analogues of this medication.

The cost of Ruzam is quite high; a box of five 0.2 ml ampoules costs approximately $25.

Reviews of the drug Ruzam

Many patients have already experienced the effects of the drug Ruzam, because all people suffering from this disease want to get rid of allergies.

Some of those who underwent treatment were satisfied with the result, others did not identify certain advantages of the medication.

Bronchial asthma has been accompanying me for more than 10 years, and attacks become more frequent in the spring.

My pulmonologist advised me to put Ruzam three years ago and now I resort to this remedy every year. I start the course around January and finish it by spring.

Naturally, I cannot completely eliminate all the symptoms of my illness, but I am pleased with the absence of severe suffocation and almost always feel quite good.

Ruzam helped me reduce the symptoms of hay fever. I completed one course, but for the second I couldn’t get the medicine. I was afraid to order online.

Anatoly, 32 years old.

Ruza was discharged from recurrent urticaria. The drug did not help at all and the reason for this is that they incorrectly determined what caused the spots on my body.

A visit to another doctor allowed me to find an effective drug. And I feel so sorry for wasting money on Ruzam.

I took Ruzam on the advice of a friend and thereby provoked the development of certain disorders in my body, so I had to stay in the hospital.

The doctor scolded me, and after the examination she prescribed a completely different drug. Given my illness, Ruzam could only do harm.

Only Ruzam helped me with allergic rhinitis. I experienced attacks of sneezing and nasal congestion in response to dust and various plants.

I’ve been piercing my ruza twice a year for five years, and so far I’m quite happy with the results.

My daughter was prescribed Ruza for bronchial asthma. Honestly, after the first two injections I wanted to refuse, as the cough got worse and the weakness got worse.

But the doctor explained that this happens and advised not to interrupt the treatment.

Three months have passed since we administered the first 10 injections of the drug and now I want to say that positive results Yes, and my daughter’s mood also improved.

Ruzam specifically did not help me at all with my asthma. But a friend from the hospital allowed me to almost completely get rid of attacks.

Anna Petrovna, 53 years old.

Assigned to Ruzam from contact dermatitis, the drug did not help at all, moreover, all the skin changes only intensified. Now, as before, I save myself with hormonal ointments.

Every spring and almost all summer, my son literally suffered from rhinitis. His cough and nasal congestion did not allow him to play outside for a long time.

A wide variety of drugs were used for treatment, but it became easier only after a course of Ruzam.

At first next year I want to spend re-treatment child.

I put one course on Ruzam, and I couldn’t believe how easily I got through this spring and summer. There was virtually no sneezing, no nasal congestion, and no discharge. I am pleased.

To summarize, we can say that Ruzam is a medicine that should not be taken on the recommendation of friends or on one’s own initiative.

The drug should only be prescribed by a doctor, otherwise, at best, you will not get a therapeutic effect and will waste your money.

And in the worst case, harm your body.

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Ruzam

Allergic rhinitis (seasonal, year-round), bronchial asthma, urticaria, Quincke's edema, allergic dermatitis, recurrent respiratory infections.

Acute infection, active tuberculosis, decompensated diseases of internal organs, pregnancy.

Pharmacological action - immunomodulatory, antiallergic. Reduces the reaction of passive cutaneous anaphylaxis, the level of reagin antibodies in the blood, promotes the activation of cellular immunity, and has an anti-inflammatory effect.

›› L03AX Other immunostimulants

›› J30 Vasomotor and allergic rhinitis

›› J39 Other upper respiratory tract diseases

›› L20 Atopic dermatitis

›› T78.3 Angioedema

Extract from a thermophilic strain of Staphylococcus aureus (St.aureus, strain C2). Solution for subcutaneous administration in 0.2 ml ampoules, 5 ampoules in a blister pack, 1 pack in a cardboard box.

Colorless transparent liquid.

Reduces the severity of general and local allergic reactions.

Exacerbation reactions: low-grade body temperature, weakness, malaise, increased cough and/or rashes (with allergic skin reactions).

SC, in a single dose of 0.1–0.2 ml every 5–7 days, course of treatment – ​​6–10 injections. If necessary single dose increase to 0.2–0.3 ml and administer every 5 days. Repeated courses are carried out according to the same scheme up to 4-5 times a year at intervals of at least 20 days. For hay fever, 1–2 preventive courses are recommended before the flowering period.

The development of exacerbation reactions indicates a positive therapeutic effect. If they are severe (isolated cases), a combined prescription with antihistamines, glucocorticoids, and antibiotics is recommended.

List B.: In a place protected from light, at a temperature of 4–20 °C.

Found in 154 questions:

Is it possible to combine two treatments? Take anti-infective tablets for allergies and tablets for gastritis. I was prescribed to take Dezal and Ruzam against allergies. And for gastritis Ursosan and Trimedat. open

Dear doctors! I was prescribed the drug Ruzam for year-round allergic rhinitis (for dust). Today I had my first injection. It seems to have gone well. Are there any restrictions on execution physical exercise? And if so, which ones? Thank you. . open

Hello! Please tell me where to give the Ruza injection? open

A 2-year-10-month-old child with bronchial asthma was prescribed the drug Ruzam, dose 0.1, and once a week the instructions say that he starts at 4 years old, isn’t it too early? open

Hello, I have hay fever (birch, alder), the doctor prescribed 10 ampoules for Ruza for 2.5 months, that is, one ampoule once a week. Tell me whether I should follow a diet, and if so, what should be excluded from the diet? And is it possible to drink alcohol? open

Is it possible to give Ruzam injections when a child has a fever or a sore throat? They've already injected me 3 times. open

Antiallergic human Histoglobulin No. 5 was prescribed, this drug not on the territory of Kazakhstan and Russia (they ordered the drug Ruzam, which seems to be an analogue of Histoglobulin). After that, they prescribed a course of prednisolone, and then lycopid. They also took it. open

Everything is correct, the only hope is for Ruzam. Acupuncture is unlikely. Remove all household chemicals and plants and soil from the house. While you can save yourself with injections of prednisolone, keep it on hand! look

Hello! A child aged 4 years 9 months was prescribed Ruzam, here allergic rhinitis, allergy upper respiratory tract (exacerbation begins in autumn and spring). Is it possible to inject it at this age or can you do without it? I have no doubt about the doctor's competence. open

Hello. I have been worried about aquagenic urticaria for a long time, I don’t know how to cure it. I even tried Ruzam. Please tell me whether it is possible to completely get rid of it, or just muffle its symptoms with antiallergic H1-blocker tablets. open

Hello, please tell me I have allergies every year from June to September. My eyes are very itchy, I have snot, I sneeze 100 times, my throat swells, turns red and becomes... open

See an allergist only after the season and after 2 months, but Ruzam is very good injections I prick myself before the season, it’s very nice I’ve been allergic to all weeds for 4 years look

Staphylococcus aureus. all the skin is rough, the child is tearing all the skin into blood, the doctors for a long time could not find what it was until they themselves took tests. Now we have been prescribed Ruza, do you think it will help us or maybe buy something else to try. open

RUZAM

Solution for subcutaneous administration

0.2 ml - ampoules (5) - contour cell packaging (1) - cardboard packs.

0.2 ml - ampoules (5) - contour cell packaging (2) - cardboard packs.

Solution for subcutaneous administration in the form of a clear, colorless or slightly colored liquid with light odor phenol.

Excipients: sodium chloride (solution for injection 0.9%), phenol (0.025-0.05%).

0.5 ml - ampoules (5) - contour cell packaging (1) - cardboard packs.

0.5 ml - ampoules (5) - contour cell packaging (2) - cardboard packs.

Has anti-inflammatory and anti-allergic effects. Reduces swelling of the mucous membranes and skin, reduces the content of eosinophils and degranulated mast cells at the site of inflammation and increases the concentration of secretory immunoglobulin class A in the mucous membranes, thereby increasing their resistance to infection. Reduces the content of markers of allergic inflammation: total immunoglobulin class E in the blood and nitric oxide in the exhaled air.

Seasonal (hay fever) and year-round allergic rhinitis, bronchial asthma, urticaria and angioedema, atopic and other allergic dermatitis, frequent respiratory infections.

Hypersensitivity to the drug, pregnancy and breastfeeding, children under 4 years of age, acute infection, active tuberculosis, decompensated diseases of internal organs.

Carefully. Use with caution in the presence of lesions chronic infection (chronic tonsillitis, sinusitis) due to the possibility of their exacerbation.

Subcutaneously for adults and children over 6 years old, 0.2 ml once a week, for children from 4 to 6 years old, 0.1 ml once a week; course 5-10 weeks. From 1 to 4 courses can be conducted during the year. For hay fever, the drug is administered 6-8 weeks before the flowering period of the allergenic plant; for frequent respiratory infections, prevention should be carried out in spring and autumn.

Increase in body temperature to subfebrile levels, weakness, exacerbation of a chronic source of infection, short-term increase in cough during chronic bronchitis, increased skin rash with skin allergies. These symptoms, as a rule, are mild and transient and do not require discontinuation of the drug.

Interactions of the drug RUZAM with other drugs have not been registered. RUZAM can be prescribed together with antihistamines, glucocorticosteroids or antibiotics.

The drug has no effect on the performance of potentially dangerous species activities requiring special attention and reaction speed (driving, etc.).

Do not use the remaining solution in the ampoule.

Store the drug in a place protected from light and out of reach of children at a temperature of 4 to 20°C.

Shelf life: 4 years, do not use too late indicated on the packaging.

To ask a question about the project or contact the editors, use this form.

Almost every person has experienced what an allergic reaction is at least once in their life. In some people, the reaction to the allergen manifests itself in the form skin rash, in others - swelling of the mucous membranes, in others - a runny nose. And if this situation happened once, then there is no need to worry, but in case of seasonal allergies, it is better to consult a doctor and choose an effective antiallergic drug. One of these is the “Ruzam” product, instructions for use of which will be presented to your attention later in the article.

Composition and release form of the product

When creating this drug, pharmacists use an extract from a culture of the isolated thermophilic strain C-2 of Staphylococcus aureus. Phenol and sodium chloride are used as additional components. A colorless or slightly colored solution for subcutaneous injection with a characteristic odor is packaged in ampoules with a dosage of 0.2 and 0.5 ml.

In a cardboard pack of the drug, in contour packages, there are 5 or 10 ampoules, depending on the type of packaging. In the pharmacy chain, the medicine “Ruzam” (the instructions warn about this) is dispensed only with a prescription from the treating doctor.

How the drug works: pharmacological properties

The mechanism of action of the drug “Ruzam” is quite original, as it affects several links immune system. In the human body, such a chain is quite large. But the humoral “link” is responsible for the manifestation of allergies, which, under the influence of an allergen, exhibits an excessive reaction.

As described by the available drug « Ruzam" instructions for use, its active substance activates the cellular mechanism of immunity, thereby suppressing the humoral link. As a result of this effect, the level of eosinophils in the patient’s blood decreases, and the number of mast cells in the site of inflammation decreases. Already 20-30 minutes after the injection, the level of antibodies to the allergen sharply decreases, and the manifestation of cutaneous passive anaphylaxis also significantly decreases.

Advantageous features of the medicine

In addition to the pronounced antiallergic effect of Ruzam, the instructions describe its anti-inflammatory properties. They are achieved by increasing the content of secretory immunoglobulin A class in the mucous membranes. As a result, their resistance to various infections increases significantly.

After just one injection, the test results of patients clearly demonstrate an active decrease in the indicators of the allergic inflammatory process. Doctors also note a reduction in the level of immunoglobulin E class and the amount of nitric oxide in exhaled air.

Who is the drug indicated for?

Thanks to the complex original mechanism of action, the instructions recommend using “Ruzam” (an allergy medicine) for the following diseases:

  • bronchial asthma;
  • allergic rhinitis;
  • seasonal hay fever;
  • dermatitis of allergic origin.

The medication is used to prevent frequent respiratory ailments in pediatrics. It is prescribed to children from 4 years of age who suffer from seasonal acute respiratory viral infections and acute respiratory infections.

Medicine dosing system

This medication is used exclusively for subcutaneous injections. The recommended single dose for adult patients and children over 6 years of age is 0.2 ml. The interval between injections is 7 days. The duration of therapy is prescribed individually and varies from 5 to 10 weeks.

As for the junior group For patients aged 4 to 6 years who are prescribed the drug "Ruzam", the instructions for use for children limit them to a single dosage of up to 0.1 ml. The treatment regimen for small patients is identical to the recommendations for adult patients - the injection should be given once a week.

The decision on the need for repeated courses of treatment rests with the attending physician. If necessary, the patient can undergo 4 courses of therapy per calendar year. With severe seasonal hay fever, patients are recommended to undergo treatment 6-8 weeks before the onset of the allergen. For children who often suffer from seasonal respiratory infections, pediatricians prescribe 2 courses per year. It is advisable to carry them out in autumn and spring.

Contraindications: who should not use the product?

It is strictly prohibited to use the medicine to treat allergies in children under four years of age. The instructions for use do not recommend using the product “Ruzam” (0.2 ml) for patients suffering from the following ailments:

  • active form of tuberculosis;
  • decompensated diseases of internal organs;
  • acute infections.

Hypersensitivity to the active substance or auxiliary components of the drug is also a serious reason to refuse its use.

The instructions recommend prescribing Ruzam to patients with chronic infections, including sinusitis and tonsillitis, with caution, since in these cases the risk of exacerbations increases significantly.

Use of drugs during pregnancy and lactation

For expectant mothers, using the medicine throughout pregnancy is strictly prohibited, since the effect of an extract from a strain of Staphylococcus aureus on the fetus has not been studied.

During lactation, the drug is also not prescribed, because the active substance enters the newborn’s body with mother’s milk and can cause a number of dangerous reactions. In situations where it is not possible to replace the medicine with another, women are advised to stop breastfeeding and only then begin therapy.

Side effects of the medication

Prescribing treatment with the drug "Ruzam", the doctor mandatory should inform the patient about the following possible reactions body:

  • an increase in body temperature within the subfebrile range;
  • loss of strength and lethargy;
  • drowsiness;
  • increased cough (short-term) in patients with chronic bronchitis;
  • and when skin dermatitis about a slight increase in rashes.

Unlike other drugs, the instructions for use of Ruzam do not recommend stopping it if such reactions occur. Such manifestations, on the contrary, indicate positive dynamics. Typically, side effects are mild and do not require adjustment of the dosage system.

In isolated cases, when the symptoms described above are clearly manifested, it is necessary to contact your doctor, who will be able to select effective drugs. These can be antibacterial or antihistamine drugs, the action of which neutralizes the side symptoms of the drug "Ruzam".

After completing the course of therapy, the patients’ well-being improves significantly, and side symptoms disappear.

Overdose and interaction with other drugs

During the entire period of use of the drug, no cases of overdose were recorded. All complaints about various reactions of the body were only a consequence of the side effects of the active substance.

But if, by chance, a large dose of medication was injected subcutaneously, you must immediately contact medical institution. Doctors will select appropriate symptomatic therapy.

Based on the results of numerous studies, it has been established that the use of the drug can be combined with antibacterial therapy, as well as with the use of glucocorticosteroids and antihistamines.

The occurrence of any adverse reactions with various combinations was not established. Therefore, when prescribing the drug “Ruzam”, it is recommended to take into account only the patient’s age and the presence of diseases for which it is contraindicated.

Structural analogues of the product

The composition of the drug “Ruzam” is unique, since it is based on an extract of one of the strains of Staphylococcus aureus. Therefore, the drug has no structural analogues in the form of a solution.

The only medicine based on an identical active ingredient is Ruzam cream. The instructions for use recommend using it as a prophylactic for skin care for people prone to allergies. The cream softens the skin and strengthens the cellular immune system, which increases the resistance of the epidermis to various infections and allergic reactions.

Cream "Ruzam": application features

The drug is applied to skin a thin layer once a day for prophylactic purposes. If the first signs of infection or a characteristic allergic rash have already appeared on the skin, daily dose It is recommended to double it. That is, the cream must be applied to the affected areas in the morning and before bed. The duration of treatment is completely individual, and should only be determined by an experienced doctor.

Like the solution, the cream has a number of contraindications that need to be taken into account before starting treatment. These include:

  • acute infectious processes of various etiologies;
  • active form of tuberculosis;
  • individual increased sensitivity to the components of the product;
  • pregnancy and lactation;
  • age up to 4 years;
  • decompensated diseases of internal organs.

How to replace the product: analogues

If you need to replace the Ruzam product, the instructions for use do not describe analogues. And this is quite logical, because, as already mentioned, the medicine has no structural analogues. Therefore, if for some reason the patient cannot purchase the product or does not want to use it, fearing the consequences of side effects, it is recommended to consult a doctor.

The specialist will select an effective medicine or a set of medicines that will help cope with allergies. Self-medication in such a situation is strictly prohibited, because the body’s reaction can be unpredictable.

Ruzam is a modern antiallergic drug that has an original principle of action on the human body.

This drug is sold in the form of ampoules with a solution for subcutaneous injection. It is produced by the pharmaceutical company Ruzam-M LLC.

General information about the drug

Ruzam is a medicinal water solution for subcutaneous injection, which is clear liquid, having a faint odor of phenol.

The main component in Ruzam is an extract from cultures of heat-resistant strains of Staphylococcus aureus. The product also contains auxiliary components such as sodium chloride and phenol.

The medicine Ruzam is sold in the Russian pharmacy chain in cardboard packages, each of which contains five ampoules of the drug with a volume of 0.2 milliliters.

Impact on the body

Ruzam has a pronounced anti-inflammatory and anti-allergic effect. It also allows you to significantly reduce swelling of the skin and mucous membrane while simultaneously reducing the concentration of eosinophils and degranulated cells at the site of the inflammatory process. In addition, Ruzam stimulates the production of secretory immunoglobulin A in the mucosa, which increases its resistance to the effects of pathogenic microflora. Ruzam makes it possible to reduce the concentration of the main inflammatory allergic markers, which generally improves general state person after contact with allergens.

Patients taking this medication have clinically demonstrated a decrease in allergic markers, indicating the overall effectiveness of the drug. At the same time, the level of immunoglobulin E decreases in the patient’s blood, while the concentration of nitric oxide in the person’s exhaled air decreases.

Indications and contraindications for taking the drug

The main clinical indications for the use of this drug include:

  • chronic rhinitis of an allergic nature;
  • various forms;
  • development ;
  • emergence;
  • allergic and non-allergic origin;
  • chronic respiratory infections.

The main contraindications for the use of Ruzam are as follows:

  • individual high sensitivity to the individual components that make up the drug;
  • development of acute infectious diseases inside the body;
  • active form of tuberculosis;
  • diseases of internal organs of a decompression nature;
  • pregnancy and breastfeeding;
  • under four years of age.

Instructions for use of Ruzam for allergies for adults and children

How to take this medicine is described in detail in the instructions for the drug. Children aged 4 to 6 years are often prescribed a course of Ruzam as an injection once a week at a dosage of 0.1 milliliter. For children over 6 years of age and adult patients, Ruza is prescribed in a dosage of 0.2 milliliters once a week. In both cases, the course of taking the drug is from 5 to 10 weeks. Over the course of a calendar year, up to four treatment courses are allowed.

In case of hay fever in a patient, the use of this medicine is prescribed 1.5-2 months before the start of the period of active flowering of plants. In the presence of chronic respiratory diseases the drug is used as preventative measure in autumn and spring.

As for the use of Ruzam by pregnant women, as well as breastfeeding mothers, its use by such patients is not recommended.

Ruza is not prescribed for children under 4 years of age.

How does an overdose manifest and what side effects may occur?

Clinical studies have not established the amount of drug at which an overdose may occur. However, in case of individual intolerance to certain components of Ruzam, you should immediately consult a doctor and take an antihistamine.

When using this medicine, the following adverse reactions are observed in some cases:

  • a sharp increase in body temperature, accompanied by chills and headache;
  • appearance general weakness muscles;
  • exacerbation of infectious diseases and pathologies;
  • increased cough with short-term bronchitis;
  • increased skin rashes of allergic origin.

All such symptoms are most often mild in nature, which allows them to quickly pass on their own without the need to stop taking Ruzam.

The drug has an official website, which has a feedback form that must be filled out in case of side effects.

Special instructions for use

To date, Ruzam's interaction with other drugs has not been clinically established. pharmacological agents. This medicine may be prescribed together with various antihistamines, antibiotics or glucocorticosteroids.

Also, the drug does not affect a person’s concentration in any way, which allows vehicle drivers to take it freely and operate various complex mechanisms.

If you have impaired renal or liver function, the use of this drug should be under the close supervision of a physician with regular testing.

Evaluation of doctors and patients

Reviews from doctors and patients about the allergy drug Ruzam are mostly good. Its high efficiency is noted.

My medical practice, which lasts for more than 15 years, has shown that Ruzam is able to significantly reduce the manifestations of seasonal allergies. Many patients note significant relief from the second week of the course. At the same time, those people who have individual sensitivity to its individual components should approach the use of this product with caution.

Alexey Ivchenkov, allergist

For me, the main advantage of Ruzam is that this drug is a non-hormonal drug with a pronounced effect. With his help I got rid of my atopic dermatitis. The course of treatment lasted two months, during which I went to the clinic for an injection once a week. To achieve the full effect of the cure, I had to undergo three two-month courses of treatment with this drug, after which I felt real relief from getting rid of my problem.
Now my skin has regained healthy looking and the constant itching no longer bothers me. Of course, my disease is recurrent, so it is impossible to cure it completely, but thanks to Ruzam, I have been in stable remission for almost three years. Maria, 45 years old

I have suffered from allergies since childhood. After I unsuccessfully tried a bunch of different medications while self-medicating, I finally decided to go to an allergist. The doctor prescribed me an appointment with Ruzam. At first, I really began to notice some improvement in my condition. When repeating a course of special positive effect I didn't watch anymore. The same can be said about the third one. For this reason, I had to stop using Ruzam due to the fact that this drug works extremely poorly for me.

Victoria, 25 years old

According to patient observations, taking Ruzam does not make contact with plant pollen safe. For this reason, you should be very careful during the period of active flowering of plants and keep traditional antihistamines with you. It is also important to be under close medical supervision when taking a course of Ruzam in case of chronic inflammatory diseases kidneys, since sometimes patients note a deterioration in the condition of these organs.

The main advantage of this drug is its effectiveness with rare injections. Also, its advantages often include the fact that it is not a hormonal agent.

As for the disadvantages of Ruzam, they include a fairly extensive list of side effects, although they appear quite rarely. Often, while taking this drug, there is an increase in body temperature and, as a result, chills, accompanied by a headache. Also, many are not satisfied with the relatively high cost of this drug in comparison with other antiallergic pharmacological agents.

How much does it cost and how is it stored?

Average market price Ruzama in domestic pharmacies costs 1,600 rubles. Dispensing the drug requires a prescription from a doctor.

Storing this medicine requires maintaining a temperature range from 4 to 25 degrees Celsius. It is also important to ensure that the place where Ruzam is stored is completely protected from direct contact sun rays and from children. The shelf life of the drug from the date of its manufacture is 4 years.

Analogs

To date, there are no pharmacological drugs that have a similar composition to Ruzam. For this reason, we can say that this drug has no analogues. If the doctor has prescribed this medication to the patient, but the patient cannot find it in the pharmacy chain, it is necessary to select an allergy medicine with similar properties, but with a different composition and main active substance. With a competent approach and taking into account all the specifics clinical picture for a particular patient, an experienced doctor will be able to choose the most successful and effective alternative for this medicine.

For the treatment of various allergic ailments, not only local antiallergic, anti-inflammatory and decongestant drugs, as well as systemic drugs, are used, but also drugs with a direct antiallergic effect. Such drugs include Ruzam. In our article we will describe the instructions for use of the drug Ruzam, analogues of this drug, adverse reactions and contraindications.

Ruzam is a solution with antiallergic effect. This drug has a clear anti-allergic and anti-inflammatory effect. After its use, swelling of the skin and mucous membranes decreases, and the concentration of eosinophils in the blood and degranulated mast cells in the inflammatory focus also decreases. In addition, Ruzam injections help increase the amount of secretory immunoglobulin A, which is concentrated in the mucous membranes. Thanks to this medication, resistance increases human body to all kinds of infections. After its use, the concentration of markers of the allergic inflammatory process decreases, that is, nitric oxide in the air exhaled by the patient, and total immunoglobulin E in the blood plasma.

Instructions for use and composition


The main active ingredient of the antiallergic drug is an extract of Staphylococcus aureus, namely its thermophilic strain. The drug Ruzam also contains the following auxiliary components:

  • sodium chloride;
  • phenol.

The drug is supplied in ampoules of 0.2 and 0.5 ml. They are placed in blister packs of five pieces. One cardboard box can contain 1 or 2 contour packages.

Indications for the use of this medicine are as follows:

  • allergic year-round rhinitis and seasonal rhinitis (hay fever);
  • Quincke's edema;
  • hives;
  • bronchial asthma;
  • skin diseases, namely atopic dermatitis and the presence of other allergic dermatitis;
  • frequent incidence of respiratory infections.

Special drug interactions not detected with other medications. Ruza is allowed to be used in conjunction with antibiotics, glucocorticosteroid drugs and antihistamines.

Side effects


This allergy medicine has the following contraindications for its use:

  1. Hypersensitivity to some ingredients of the drug;
  2. The period of bearing a baby;
  3. Breast-feeding;
  4. The medicine is not prescribed to children under four years of age;
  5. Acute infectious processes are a contraindication to the use of this drug;
  6. Active form of tuberculosis;
  7. Pathologies of internal organs (decompensated).

Attention! Ruzam is prescribed with extreme caution if there are chronic infectious foci in the patient’s body, for example, with chronic sinusitis or tonsillitis. This is due to the fact that while taking the medication, infectious processes may worsen.

When using any drug, side symptoms are observed. As for the drug Ruzam, then side effects from its use are the following:

  • during treatment, body temperature may increase (only to subfebrile levels);
  • exacerbation of chronic infectious processes in the human body;
  • general weakness;
  • with chronic bronchitis, a rapid increase in cough may be observed;
  • if there are skin allergic reactions, the rashes may worsen.

As a rule, the appearance of the above adverse reactions is mild and passes quickly, so you should not refuse to use the drug. If you purchased Ruzam, the instructions for use state that the drug does not have a negative effect on the rate of reactions, therefore from the administration vehicles and performing potentially hazardous activities during treatment may not be avoided.

Directions for use and doses


The drug is administered subcutaneously to children over six years of age and adults in a volume of 0.2 ml once a week. For the treatment of children from four years of age to 6 years of age, a volume of the drug equal to 0.1 ml is used, which is also administered subcutaneously once every seven days. The duration of therapy is from five to ten weeks. You can conduct from one to four such courses per year.

To treat hay fever, the drug is administered six or eight weeks before the start of the flowering period of grasses, trees and plants to which the patient is allergic. When preventing frequent respiratory infectious diseases, a course of treatment is carried out in the spring and autumn.

Analogues of the drug

Many patients are looking for analogues of Ruzam, but according to pharmacists and doctors themselves, this drug has unique composition, so it has no analogues. If you cannot find Ruzam in the pharmacy, the only thing that can be advised in such a situation is to consult a doctor again to prescribe other antiallergic tablets or injections. Remember that only a doctor can select drug analogs or drug replacements.

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IDermatolog.ru

Ruzam

Active substance:

Pharmgroup:

Other immunomodulators

Instructions:

Clinical and pharmacological group

13.003 (Drug with antiallergic effect)

Release form, composition and packaging

0.2 ml - ampoules (5) - blister packs (1) - cardboard packs. 0.2 ml - ampoules (5) - blister packs (2) - cardboard packs.

Solution for subcutaneous administration in the form of a clear, colorless or slightly colored liquid with a slight phenol odor.

Excipients: sodium chloride (solution for injection 0.9%), phenol (0.025-0.05%).

0.5 ml - ampoules (5) - blister packs (1) - cardboard packs. 0.5 ml - ampoules (5) - blister packs (2) - cardboard packs.

pharmachologic effect

Has anti-inflammatory and anti-allergic effects. Reduces swelling of the mucous membranes and skin, reduces the content of eosinophils and degranulated mast cells at the site of inflammation and increases the concentration of secretory immunoglobulin class A in the mucous membranes, thereby increasing their resistance to infection. Reduces the content of markers of allergic inflammation: total immunoglobulin class E in the blood and nitric oxide in the exhaled air.

Dosage

Subcutaneously for adults and children over 6 years old, 0.2 ml once a week, for children from 4 to 6 years old, 0.1 ml once a week; course 5-10 weeks. From 1 to 4 courses can be conducted during the year. For hay fever, the drug is administered 6-8 weeks before the flowering period of the allergenic plant; for frequent respiratory infections, prevention should be carried out in spring and autumn.

Drug interactions

Interactions of the drug RUZAM® with other drugs have not been registered. RUZAM® can be prescribed together with antihistamines, glucocorticosteroids or antibiotics.

Side effects

Increase in body temperature to low-grade levels, weakness, exacerbation of a chronic source of infection, short-term increase in cough in chronic bronchitis, increase in skin rashes in skin allergies. These symptoms, as a rule, are mild and transient and do not require discontinuation of the drug.

Storage conditions and periods

Store the drug in a place protected from light and out of reach of children at a temperature of 4 to 20°C.

Shelf life: 4 years, do not use after the expiration date indicated on the package.

Indications

Seasonal (hay fever) and year-round allergic rhinitis, bronchial asthma, urticaria and angioedema, atopic and other allergic dermatitis, frequent respiratory infections.

Contraindications

Hypersensitivity to the drug, pregnancy and breastfeeding, children under 4 years of age, acute infection, active tuberculosis, decompensated diseases of internal organs.

Carefully. It should be used with caution in the presence of foci of chronic infection (chronic tonsillitis, sinusitis) due to the possibility of their exacerbation.

special instructions

The drug does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving a car, etc.).

Do not use the remaining solution in the ampoule.

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Registration numbers

Solution for subcutaneous administration 0.2 ml: amp. 5 or 10 pcs LS-000791 (2025-11-10 – 2025-11-15)
solution for subcutaneous administration 0.5 ml: amp. 5 or 10 pcs LS-000791 (2025-11-10 – 2025-11-15)

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Compound

Ruzam contains extract from a culture of a thermophilic strain of Staphylococcus aureus(Staphylococcus aureus, strain C-2). In addition, the composition includes phenol 0.025–0.05%, 0.9% sodium chloride solution.

Release form

Pharmacies sell a solution for subcutaneous injection. The cell packaging contains 5 ampoules. The packages are placed in a cardboard box.

pharmachologic effect

Antiallergic And immunomodulatory means.

Pharmacodynamics and pharmacokinetics

Ruzam represents anti-inflammatory And antiallergic medicine. It reduces edema mucous membranes and skin, increases the level secretory Ig class A in mucous membranes, helps reduce the amount degranulated mast cells And eosinophils at the site of inflammation, and also reduces the level markers of allergic inflammation. Expressiveness allergic reactions when taking this drug it decreases.

Indications for use

The medicine is used for:

Contraindications

Prohibited to do injections in case of a negative reaction to the components of the drug, lactation, pregnancy, acute infection, decompensated diseases internal organs and tuberculosis in an active form. In addition, contraindications include age under 4 years.

Side effects

Possible exacerbation reactions: malaise, weakness, low-grade fever body, worsening cough or rash. Usually these symptoms are mild, go away on their own and do not require discontinuation of use.

Instructions for use of Ruzam (Method and dosage)

Instructions for use Ruzama states that the drug is administered subcutaneously. From the age of 6 years, injections of 0.2 ml are given. For children 4-6 years old, dosages of 0.1 ml are recommended. The injection is given once every 7 days. Treatment can last from 5 to 10 weeks. There can be from 1 to 4 such courses per year. The interval between them should be at least 20 days.

When hay fever injections done 6-8 weeks before the plant that causes the allergy begins to bloom. For the purpose of prevention with frequent respiratory infections the drug is used in spring and autumn.

Instructions for use of Ruzam indicate that, if necessary, the dose can be increased to 0.3 ml, which is administered every 5 days.

Overdose

No information on overdose was provided.

Interaction

There is no significant interaction with other agents.

Terms of sale

The medicine is sold in the pharmacy network only with a doctor's prescription.

Storage conditions

The medicine should be kept out of the reach of small children and in a dark place. The storage temperature for ampoules with the drug is 4-20°C.

Best before date

Four years. Do not use ampoules with medicine after the expiration date indicated on the packaging.

Ruzam's analogs

Level 4 ATX code matches:

Currently, the drug is considered unique in its properties. Structural analogues of Ruzam with the same active ingredient are not available.