What is better for sinusitis: Sumamed or Amoxiclav? What is better amoxiclav or azithromycin. Which antibiotic is better: Amoxiclav, Sumamed or Augmentin. Interaction with other substances

Usually, for various bacterial infections, antibiotics related to certain group. Effective and widely used drugs are and.

These antibiotics are available in various forms oh and render effective action against gram-negative and gram-positive pathogenic bacteria. Many patients are concerned about the question: what anti bacterial agent of data is more secure and efficient?

Azithrimycin is the base component of Sumamed

is a drug that belongs to the group of macrolide antibiotics. It is an azalide that has a prolonged action. It prevents the growth and reproduction of pathogenic bacteria developing in the inflammatory focus.

Gram-positive and gram-negative microorganisms are sensitive to Sumamed. Particularly effective against mycoplasma and ureaplasma.

The antibiotic is available in the following pharmaceutical forms:

Tablets of 125, 250 and 500 milligrams. The tablets are coated with a blue film-like coating. They are convex on both sides and have engraving.
Powder for making syrup, 100 milligrams per 5 milliliters. May have a light yellow or white tint, with a strawberry scent. After the powder dissolves, a homogeneous liquid with a light, slightly yellowish tint is formed.
Powder for forte suspension, 200 milligrams per 5 milliliters. It is characterized by the same properties as the above 100 mg powder. May have a different smell.
Capsules of 250 milligrams. They are gelatinous and have a lid. of blue color and blue body. The capsules contain a light yellow or white.

The tablets contain the active ingredient azithromycin. Auxiliary ingredients included in the composition include:

Hypromellose
Corn starch
Calcium hydrogen phosphate
Pregelatinized starch
Magnesium stearate
Polysorbate
Sodium lauryl sulfate
Titanium dioxide
Talc
Dye

More information about antibacterial drugs can be found in the video:

In the composition of the powder for syrup -200 mg active ingredient– azithromycin. It contains the following excipients:

Anhydrous trisodium phosphate
Sucrose
Xanthan gum
Colloidal silicon dioxide
Titanium dioxide
Hyprolose
Hydroxypropyl cellulose
Banana, cherry and vanilla flavors

Additional substances of the drug in capsule form are:

Magnesium stearate
Cellulose in microcrystals
Sodium lauryl sulfate
Titanium dioxide
Indigo carmine
Gelatin

Thus, the composition depends on the form of the drug. The active ingredients are the same, only in certain dosages. Regarding the excipients, they are different for each form of Sumamed.

When an antibiotic is prescribed, contraindications

Sumamed is prescribed for the following pathological conditions organs respiratory system and otolaryngological diseases:

Bronchotracheitis

Widely used for the treatment of inflammatory and infectious diseases of soft tissues and skin, which include:

Impetigo
Erysipelas
Secondary dermatoses

In addition, the medicine is used for diseases genitourinary system, namely for the treatment of cervicitis, urethritis of various origins, erythema migrans. Prescribed for Lyme disease.

They treat sexually transmitted pathologies caused by chlamydia with antibiotics.

However, there are some restrictions regarding the use of Sumamed. The antibiotic is contraindicated in case of hypersensitivity to the substances of the drug.

The medicine should be used with caution when liver failure and kidney pathologies. This medicine is also used under medical supervision if you are prone to allergic reactions.

Amoxiclav: composition, properties, dosage form

Amoxiclav – medicine, belonging to the group of broad-spectrum penicillins. This drug is an inhibitor of beta-lactamases of pathogenic bacteria.

Effectively acts against streptococci, staphylococci, enterococci and anaerobic infectious agents and aerobic microorganisms.

This antibiotic is produced in several forms:

Tablets of 250 and 500 milligrams. They are covered with a film-like shell.
Dispersible tablets are called Amoxiclav Quiktab. They are produced in dosages of 875 or 500 milligrams of amoxicillin per 125 milligrams of clavulanic acid.
Powder for suspension, intended for internal use.

The composition of the drug depends on the dosage form of the antibiotic. The active ingredients of the drug are:

Amoxicillin
Clavulanic acid

TO excipients tablets include croscarmellose sodium and cellulose in microcrystals.

Amoxiclav powder, from which a suspension for oral use is made, contains sodium benzoate, mannitol, sodium citrate, microcrystalline cellulose.

Part dispersed tablets includes inactive components: aspartame, talc, castor oil, yellow iron oxide, silicated cellulose in microcrystals, anhydrous colloidal silicon dioxide, flavorings.

Indications and contraindications for use

Amoxiclav is widely used in otolaryngological, therapeutic, gynecological, orthopedic practice and in maxillofacial surgery.

Indications for use are the following diseases:

Chronic bronchitis
Bronchopneumonia
Retropharyngeal abscess
Otitis media
Chronic tonsillitis
Periodontitis
Chancroid
Cystitis
Cholecystitis
Pyelonephritis
Breast abscess
Gonorrhea
Osteomyelitis

Often used in the treatment of bacterial infections of the genitourinary system, as well as for pathologies of soft tissues and skin bacterial origin. Amoxiclav is used to prevent purulent processes and sepsis after surgical interventions on the heart, kidneys, organs abdominal cavity and small pelvis.

Contraindications to the use of various forms of the drug include:

Cholestatic jaundice.
Hepatitis of bacterial origin.
Lymphocytic leukemia.
Increasing the body's sensitivity to antibiotic components.
First trimester of pregnancy.

The drug is prescribed with caution and under medical supervision when carrying a child and breastfeeding. It is usually used if the benefit to the woman’s body outweighs the risk of negative effects on the child.

Sumamed or Amoxiclav: what is the difference and which is better?

Before you find out which of these antibiotics is considered the best, it is important to remember that these drugs are chosen by a qualified specialist, taking into account individual characteristics the patient's body. Therefore, in each case, either of these two drugs may be more effective.

Sometimes, to prevent addiction, the doctor may alternate medications. In case of illness, he first prescribes one medicine, and later uses the next antibiotic for infections.

The differences between these drugs are considered to be related to different groups. is a macrolide antibiotic, Amoxiclav belongs to penicillin series. Depending on this, the main active components of the data medications are different substances.Both products are available in tablet form, capsules and suspensions. Amoxiclav is also available in the form of dispersible tablets that quickly dissolve.

The advantage of Sumamed is the duration of its use - only three days.

That's why therapeutic effect occurs faster when taking this antibiotic.However this drug significantly inferior to Amoxiclav in the list of contraindications. Sumamed has more restrictions on its use than Amoxiclav. In addition, the list of indications for the use of the latter includes diseases that are not treated with Sumamed.Therefore, it is impossible to clearly determine which drug is better. Since each antibiotic has certain advantages and disadvantages.

For infectious and inflammatory diseases, antibiotic drugs are prescribed. One of effective medicines wide range action is Amoxiclav. Antibiotics have a strong effect on the body, so they are usually selected individually. When Amoxiclav does not help, or the patient has contraindications to it, you can replace the drug with an analogue. If the price of the drug seems high to you, you can find cheaper analogues.

This goal has been difficult to achieve using different families of antimicrobials, although azithromycin used for 5 days achieved 95% eradication rates. How to make a wise decision. As with other infectious disease solutions, treatment of streptococcal pharyngitis should be based on a confirmed diagnosis and treatment with effective, safe, easily adhesive, and inexpensive compounds.

Continuing the topic

As stated in the previous paragraphs, oral alternatives include a wide range of drugs that exhibit little variation in their clinical effectiveness, their ability to eradicate bacteria, or their rate of eradication. adverse reactions. On the contrary, these alternatives vary greatly in their cost of acquisition, an aspect less known to the treating physician. Paradoxically, the diversity of compounds and costs is not accompanied by significant differences in their effectiveness or safety.

Characteristics of Amoxiclav

The drug Amoxiclav is a strong antibiotic with a combined effect. The medicine is recommended for use to destroy infections that provoke the inflammatory process.

The medicine is available in three forms:

pills;
powder for suspension;
injection powder.

All forms of antibiotics contain a combination of two active substances: amoxicillin and clavulanic acid.

The most effective, safe and cost-effective treatment options for streptococcal pharyngitis continue to be those using classical antibacterial drugs. Recommendations for the treatment of pharyngitis. Streptococci in adolescent or adult patients.

Streptococcal pharyngitis is a common reason for outpatient consultation, and its diagnosis requires the use of some method of microbiological confirmation so as not to expose large numbers of patients to unnecessary and potentially dangerous antibacterial therapy. Therefore, some experts recommend the use of confirmatory culture in these cases. Numerous alternatives are now available to manage this condition, and this has led to some confusion regarding the potential benefits of some compounds.

Amoxiclav should be used for treatment purposes strictly according to the instructions or instructions of the specialist who prescribed the drug.

respiratory and ENT organs (sinusitis, bronchitis, tonsillitis, pneumonia, otitis media, abscesses or pharyngitis);
soft, bone, connective tissue and skin;
urinary and biliary tract.

In the form of a suspension, the medicine can be used for children from birth.

Sumamed or azithromycin - which is better?

On the contrary, they are clearly distinguished by large differences in acquisition costs. In recent years, shorter treatment regimens for streptococcal pharyngitis in adult patients have also been introduced, using amoxicillin for 6 days or azithromycin or some cephalosporins for 5 days. This approach has achieved the same therapeutic efficacy as traditional drug administration and is associated with better therapeutic adherence, although in our environment this is not accompanied by a significant reduction in treatment costs.

In the form of an injection, the medicine is prescribed for the treatment of infectious lesions of the genital organs and abdominal cavity, as well as for prophylactic purposes after surgery.

Contraindications:

taking pineselin antibiotics;
allergy to the components of the composition;
lymphocytic leukemia;
pregnancy, lactation.

Cheaper analogues:

Amoxicillin;
Auglintin;
Amosin;
Azithromycin.

Other substitutes with similar pharmacological effects:

Flemoxin Solutab;
Sumamed;
Suprax;

Analogues of Amoxiclav may differ in composition, so you should always study the instructions for use to prevent harm to the body.

Comparison of cephalosporins and penicillins in the treatment of group A beta-hemolytic streptococcal pharyngitis: a meta-analysis supporting the concept of microbial coatogenicity. Are cephalosporins superior to penicillin for the treatment of streptococcal tonsillopharyngitis: is it worth the difference?

Beta-lactamase producing bacteria in the pharyngeal flora of patients with acute pharyngitis. Tonsillopharyngitis: evaluation of short-term treatment with cefuroxime axetil compared with standard 10-day penicillin therapy. A review of its use in pediatric infectious diseases. A randomized trial of seven to ten days of “therapy.” Five-day treatment with cefdinir for streptococcal pharyngitis. An open-label comparative study of azithromycin versus cefaclor in the treatment of patients with upper respiratory tract infections. respiratory tract.

There is also a difference in the price of Amoxiclav synonyms. It is not difficult to find a cheap analogue, but the available indications should be taken into account, since in certain cases substitutes with a higher dosage of the active substance are required.

Amoxicillin

Amoxicillin is a cheap analogue of Amoxiclav. The price of the drug starts from 35 rubles (depending on the form of release and the manufacturer). The maximum cost for a medicine is an average of 180 rubles.

A twice-daily regimen of erythromycin base is effective in the treatment of acute streptococcal tonsillitis. The exclusive relation of clonal annulment and chance. Of these patients, 102 were randomized to receive azithromycin or amoxicillin. Patients were assessed at baseline at ten days and at one month. Clinical assessment, according to the signs and symptoms present after ten days and after one month, consisted of classifying cases into the categories of cure, improvement or therapeutic failure.

Which drug is more expensive?

Microbiological evaluation was performed by culture of sputum samples considered suitable after white blood cell count and Gram staining. These proportions were respectively 85% against. 78% after ten days and 83% against. 78% after one month. On this spectrum, chronic bronchitis is defined as having a productive cough for at least three months, for two consecutive years. Chronic bronchitis is characterized by small-scale airway obstruction and increased mucus production.

Amoxicillin is a penicillin antibiotic that has anti-inflammatory properties. The medicine is sold in the form of capsules and tablets.

A cheap substitute contains an active component - amoxicillin, which has the main antibiotic effect.

Many patients with chronic bronchitis also have varying degrees emphysema, characterized by the destruction of air spaces and loss of elasticity of the lungs. Thus, it is sometimes difficult to identify the contribution of these two pathological processes, chronic bronchitis and emphysema in clinical manifestations in an individual patient.

During these episodes, there is a rapid deterioration in lung function, worsening airway obstruction, and even more mucus production. Several classes of antibiotics are currently available for this purpose. Diagnosis was made in the presence of two of the following criteria: increased cough, increased sputum, or worsening shortness of breath. Patients should be treated in outpatient setting and have a plain radiograph taken 48 hours before study entry, excluding pneumonia. Female patients are unable to breastfeed, are pregnant, or plan to become pregnant during the study or up to one month after the end of the study.

Indications for use are infectious diseases that cause inflammation:

ENT - organs;
genital area;
urinary system;
respiratory tract.

The drug can be used for medicinal purposes for children. During pregnancy and breastfeeding, the medicine is prescribed only if there are increased risks.

How to take for adults

In addition, women of childbearing potential should practice an effective method of contraception. All patients included in the study signed an informed consent form. The protocol was approved by the Research Ethics Committee of each of the six centers involved in the study, which was conducted in accordance with the ethical principles of the Declaration of Helsinki, the norms of Good Clinical Research, and the federal resolutions on clinical research in Brazil.

Patients who were candidates for the study were assessed at an initial consultation, during which they were questioned about their medical history and provided a complete medical checkup, in which they were held lab tests, plain CXR, spirometry, and recent aspirated purulent microscopic examination of sputum. Evaluation of sputum was done by Gram staining and culture of specimens considered adequate were defined as those with more than 25 leukocytes and less than ten squamous epithelial cells per field observed after a short optical lens increase.

Contraindications:

infectious mononucleosis;
severe form of gastrointestinal infection;
bronchial asthma;
viral respiratory infections;
allergic diathesis;
sensitivity to the components of the composition.

An adverse reaction is expressed in the form of an allergy. With long-term therapy, symptoms of dysfunction of the brain and central nervous system may occur.

Patients were then randomly assigned to treatment with azithromycin 500 mg orally daily for three consecutive days or amoxicillin 500 mg orally every eight hours for ten consecutive days. Ten days later, patients attended a second visit and were reassessed with history, vital signs examination, spirometry, and microbiological research sputum. The third and final consultation took place approximately one month after the start of treatment and included the same procedures as the second consultation.

Just like the original - Amoxicillin is sold in pharmacy chains only upon presentation of a prescription.

Augmentin

A substitute for the drug Amoxiclav 1000 - Augmentin, is produced by an English pharmaceutical company. Despite the higher price of Augmentin (average price 350 rubles), the antibiotic contains active ingredients similar to the original (amoxicillin and clavulanic acid).

Any medications used during the study were to be reported by patients, and the amount of azithromycin and amoxicillin used by patients was calculated to assess adherence to treatment. Two patient samples were reviewed to evaluate efficacy and safety. Safety assessments were conducted using an intention-to-treat sample, consisting of all patients who received at least one dose of one of the study drugs.

Patients' clinical response was classified at the second and third consultations as treatment, improvement, or failure. Treatment was defined as resolution of the signs and symptoms of the acute exacerbation, with a return to each patient's usual pattern. Improvement was defined as resolution of fever when present and incomplete resolution of other signs or symptoms, without additional need for other antibiotics. Failure was defined as failure to resolve signs or symptoms or the need for additional antibiotic use.

Augmentin is available in the form of tablets and powder (for suspension and injection).

Instructions for use include indications in the form of an infectious lesion:

skin and soft tissues;
respiratory organs;
genitourinary organ systems;
musculoskeletal system;

allergic reaction to components;
liver/kidney diseases.

For pregnant women and women breastfeeding, the medicine is prescribed in exceptional cases. Taking medication for children has the following features:

tablets – from 12 years;
suspension – from 3 months.

Most often side effects manifest themselves in the form of gastrointestinal disorders and allergies. Disorders of the nervous, circulatory, immune and urinary systems are also possible.

Amosin

Amoxiclav tablets can be replaced with the cheap Amosin. A Russian-made drug based on amoxicillin has a bactericidal effect when the body is damaged.

The advantage of Amosin is its different release form, suitable for children and adults: injection solution, granules, powder and suspension.

The composition of the drug is active for infectious diseases:

bronchitis, sinusitis and pneumonia;
pharyngitis, ear inflammation and tonsillitis;
urethritis, cystitis, etc.;
cholangitis, gonorrhea and cervicitis;
peritonitis, impetigo and cholecystitis;
listeriosis, dermatosis and borreliosis;
salmonellosis, endocartitis, sepsis and dysentery.

Contraindications:

pathologies of the gastrointestinal tract;
infectious type mononucleosis;
impaired kidney function;
hypersensitivity to components;
pregnancy;
lactation period.

Children can be given antibiotics from birth in the absence of relevant contraindications.

Amosin can cause side effects and cause an overdose. Learn more about the symptoms negative reaction body for the medication can be found in the instructions.

The price of a generic varies depending on the form of release. The minimum cost is 30 rubles.

Flemoxin Solutab

Considering the low cost of Amoxiclav, the price of Flemoxin Solutab is quite high - from 230 rubles. The price of the antibiotic is justified by the high concentration of amoxicillin (the active component) and its form - trihydrate.

Flemoxin Solutab is produced in tablets.

Just like many analogues of Amoxiclav, its mechanism of action is aimed at eliminating infectious inflammatory process in organs and tissues:

respiratory system;
skin;
muscle-articular tissue;
genitourinary area;
digestive system.

Amoxiclav and Flemoxin Solutab are synonymous in terms of pharmacological properties. The generic version of the original drug has a similar composition and has a similar effect on the body. However, given the large dosage of the active substance, Flemoxin is recommended for children over one year of age. In rare cases, the medicine is prescribed to pregnant and lactating women, as well as newborns.

Contraindications and side effects of the drug correspond to the instructions for taking amoxicillin as an active substance and are described in detail in the annotation.

Sumamed

If it is necessary to replace Amoxiclav with analogues, experts recommend giving preference to Sumamed. The substitute for the original product is a strong antibiotic with a wide spectrum of action.

Sumamed is available in the form:

tablets (125 mg/500 mg);
dispersible (dissolving in oral cavity) tablets (125 mg/250 mg/500 mg/1000 mg);
gelatin capsules (250 mg);
powder for suspension (100 mg);
lyophilisate.

The active component of Sumamed is azithromycin, active in the following indications:

diseases of ENT organs;
respiratory tract diseases;
tick-borne borreliosis;
diseases of soft tissues and epidermis;
diseases of the urinary and reproductive system.

Sumamed is active against infectious lesions. Children are usually prescribed a suspension. In contrast to the complexity and nature of the disease, adults are prescribed the drug in a certain dosage and release form.

List of contraindications:

renal and liver pathologies;
allergy to substances - components.

Depending on the form of release, there are contraindications for use in childhood:

suspension – from 6 months;
tablets (125 mg) – from 3 years;
tablets (500 mg) – from 12 years;
lyophilisate and dispersible tablets - from 18 years of age.

Sumamed has a large list of side effects, which should be studied before taking the medicine.

Price – from 230 rubles.

Suprax

When choosing what to replace Amoxiclav with, you should also pay attention to the indirect analogue of the drug - Suprax. The foreign-made medicine, unlike other analogues, is based on the substance cefixime.

Suprax is a cephalosporin antibiotic. The medicine is available in the form of capsules with a dosage of 400 mg. - for adults and granules (100 mg/5ml) for preparing a solution (suspension) - for children.

Indications:

infections of the nasal cavity and respiratory tract;
uncomplicated types of genitourinary system infections.

The generic has positive reviews when treating children.

Contraindications:

allergy to the composition;
children's age up to six months;
pregnancy;
lactation period.

Side effects are detailed in the instructions for use.

Cost – from 550 rubles.

Azithromycin

The drug Azithromycin is an antibiotic for the treatment of infectious inflammatory diseases, which is produced by Russian pharmaceutical companies.

Among inexpensive similar drugs, Azithromycin is considered one of the effective remedies against infectious lesions:

respiratory and ENT organs;
skin;
urinary system;
genital area.

Azithromycin, containing the active substance of the same name, is produced in the form of capsules with a dosage of 500 mg.

Contraindication for use is intolerance to one or more components of the drug.

Price – from 50 rubles.

If it is necessary to replace Amoxiclav with another drug, it is not recommended to select an antibiotic on your own. It should be borne in mind that medications in this group have a strong effect on the body. Buying a medicine cheaper does not mean getting the same therapeutic effect. Cheap analogues do not always have the desired effect, so it is recommended to purchase a medicine prescribed by a doctor.

High susceptibility to diseases of the upper respiratory tract is far from uncommon in our time. Unpleasant symptoms There are many infections that cause discomfort. In addition, if not properly treated, such diseases lead to complications that make the situation even worse. Often for treatment serious illnesses(various forms of sinusitis) antibiotics such as amoxiclav, sumamed and augmentin are used.

Each of these drugs has different effects and some features. But which medicine is better? In order to answer this question, we should consider each remedy separately. Only after this can certain conclusions be drawn.

Description of amoxiclav

Bacteria that cause upper respiratory tract diseases are gradually becoming more resistant to antibiotics. At the same time, science also does not stand still and is constantly developing new drugs, as well as improving old ones. Amoxiclav can be classified as such a drug. This is an improved version of amoxicillin, which is distinguished by its availability and effectiveness.

Amoxiclav is an antimicrobial and antibacterial agent, the main substance of which is amoxicillin. The medicine belongs to the group of penicillins. In addition to the main active ingredient, the structure of the medication includes clavulanic acid. The main purpose of this substance is to prevent the early breakdown of amoxicillin.

As mentioned above, all the drugs under consideration are indicated primarily for the treatment of diseases of the upper respiratory tract. We will not dwell on this. Let's consider in what cases the drug should not be used. Amoxiclav has the following contraindications:

allergic manifestations to the components of the drug;
mononucleosis and suspicions of it;
jaundice;
lymphocytic leukemia

Here it is worth mentioning the advantages of the drug. Amoxiclav can be prescribed in childhood, as well as during pregnancy. When a girl is pregnant or breastfeeding, the drug should be taken carefully. It is necessary to understand that the components of the substance are excreted in milk in small concentrations.

Any antibiotic has a number of side effects, and amoxiclav is no exception. You shouldn’t be afraid of this, because they don’t always appear. In addition, the drug is distinguished by its effectiveness. Among the undesirable effects are the following:

deterioration of the digestive system;
nausea and gag reflexes;
liver dysfunction;
development of jaundice;
allergic manifestations (itching, rash, irritation, etc.);
development of diseases of the circulatory system;
migraine;
dizziness;
convulsions;
urinary disturbance.

Basically, such effects can occur if you take the drug contrary to contraindications. The dosage must be followed exactly as prescribed by the instructions or specialist. At the first undesirable manifestations, you should consult a doctor. He will adjust the treatment and replace the drug.

Description of sumamed

Azithromycin is used as the basic component of the drug. Sumamed belongs to the latest generation of medicines. Its peculiarity lies in its versatility; it can suppress the action of many types of bacteria. Sumamed acts at the intracellular level.

The antibiotic belongs to the group of macrolides and can be prescribed when the patient does not accept penicillins. It is noteworthy that sumamed is considered quite safe drug. It can be used long time. Although such a need is not always required. Typically, the course of macrolides does not exceed 3 days.

Contraindications and side effects

Although sumamed belongs to the drug latest generation, it may not be applicable to everyone. It is worth noting that the list of prohibitions is quite small. In this regard, the drug is clearly better than the penicillin group. So, sumamed is contraindicated for:

pregnancy;
lactation period;
infancy;
intolerance to azithromycin.

The drug very rarely causes side effects. That is why it is so often prescribed to patients. Usually, recovery occurs fairly quickly, and the unwanted effects simply do not have time to manifest themselves. In rare cases, it may be possible:

feeling of nausea;
vomiting reflex;
skin rashes.

Description of Augmentin

It is worth saying right away that Augmentin is an analogue of amoxiclav. Its main component is amoxicillin. For its fruitful work, clavulanic acid is included in the composition of the medicine. Thanks to this, the medicinal effect is more pronounced.

What is the difference between amoxiclav? Which of these drugs is better? In fact, Augmentin differs only in name and manufacturer. That is why it makes no sense to compare drugs. Their action is absolutely the same.

Since agumentin is a copy of amoxiclav, the contraindications will be absolutely the same. Wide list side effects also did not change. You need to remember this when buying Augmentin. And, of course, it is not recommended to prescribe the drug yourself, as the risk of side effects increases.

Comparative analysis

It is important to understand that for diseases of the upper respiratory tract, the medicine is selected strictly individually. For some, penicillins (Augmentin, Amoxiclav) are better suited, for others - macrolides (Sumamed). There are situations when a specialist alternates medications. After one course, another is prescribed to achieve greater effectiveness, since bacteria tend to get used to the active components of the drug.

Augmentin has one clear advantage over sumamed. The drug can be prescribed to newborns, while sumamed is given to babies only from 6 months. Augmentin can also be prescribed under strict medical supervision during pregnancy and lactation. In this, the drug is clearly superior to its competitor.

Among the evaluation criteria, it is necessary to focus on the duration of treatment. This is very important indicator, especially when they begin to treat young children. Here augmentin or amoxiclav are clearly inferior. They need to be taken for a week, while the duration of taking sumamed is reduced to 3 days. Consequently, the drug acts faster and recovery occurs earlier.

When comparing amoxiclav and augmentin, you can only focus on the cost of these similar drugs. Since the first medicine appeared a little later, its price will be higher. Well, it’s unlikely that anyone will want to overpay for the same effect. This is perhaps the only serious difference between these analogues.

It is impossible to say for sure which remedy is better. All three medications have advantages and disadvantages. The main thing is that each of them can help in a specific situation. Well, the choice should be left to a specialist who will select an antibiotic on an individual basis.

Comments powered by HyperComments

Hello! My name is Anna, I'm 29 years old. I get sinusitis quite often, and every time I seek advice and a prescription from a doctor. Usually I was prescribed Sumamed, but last time I was prescribed Amoxiclav. Tell me what is better for sinusitis: Sumamed or Amoxiclav?

Hello Anna! It is quite difficult to say unequivocally which is better, Sumamed or Amoxiclav for the treatment of sinusitis, since each of these drugs has its own pros and cons. In addition, the individual characteristics of the organism are taken into account.

For example, Sumamed is a new generation antibiotic; it has a wide range of effects on pathogenic bacteria of various kinds, including those that provoke sinusitis, and belongs to the group of macrolides. It is easily digestible, causes virtually no side effects and does not require more than 5 days to take. However, it also has its disadvantages, first of all these are contraindications. Taking this drug has its own age restrictions, and it is also contraindicated during pregnancy and severe liver pathologies.

As for Amoxiclav, this drug also belongs to the broad-spectrum antibiotics, to the semi-synthetic penicillin group. Amoxiclav has a destructive effect on the walls of bacteria, as a result of which they quickly die. More often this medicine prescribed for sinusitis, otitis, cystitis, bronchitis. Amoxiclav dosage for adults is usually 2-3 times a day.

If we talk about the disadvantages of such a remedy, then first of all it is worth highlighting contraindications and side effects, including allergic reactions in the form of skin rashes, dysbacteriosis, convulsions.

As you can see, both of the above-mentioned remedies are excellent for treating such an ailment, so I recommend deciding which is better to take, Sumamed or Amoxiclav for sinusitis, together with your doctor. One thing is certain, any of the above medications will help you quickly and effectively overcome this disease.

Hypromellose
Corn starch
Calcium hydrogen phosphate
Pregelatinized starch
Magnesium stearate
Polysorbate
Sodium lauryl sulfate
Titanium dioxide
Talc
Dye

Anhydrous trisodium phosphate
Sucrose
Xanthan gum
Colloidal silicon dioxide
Titanium dioxide
Hyprolose
Hydroxypropyl cellulose

Magnesium stearate
Cellulose in microcrystals
Sodium lauryl sulfate
Titanium dioxide
Indigo carmine
Gelatin

Sinusitis
Tonsillitis
Angina
Tracheitis
Bronchitis
Bronchotracheitis
Pneumonia
Scarlet fever
Otitis
Laryngitis
Pharyngitis

Impetigo
Secondary dermatoses

Amoxicillin
Clavulanic acid

Pneumonia
Chronic bronchitis
Bronchopneumonia
Sinusitis
Retropharyngeal abscess
Otitis media
Chronic tonsillitis
Periodontitis
Chancroid
Cystitis
Cholecystitis
Pyelonephritis
Breast abscess
Gonorrhea
Osteomyelitis

Cholestatic jaundice.
Lymphocytic leukemia.
First trimester of pregnancy.

Continuing the topic:

How effective is Sumamed for angina?
How to properly use Sumamed for angina?
How to choose an antibiotic to treat a sore throat?

Video: How a doctor chooses an antibiotic

Sources:

Clinical recommendations (treatment protocol) for the provision of medical care children with tonsillitis (acute streptococcal tonsillitis), FSBI NIIDI FMBA RUSSIA, State Budgetary Educational Institution of Higher Professional Education Krasnoyarsk State Medical University named after. prof. V.F. Voino-Yasenetsky Ministry of Health of the Russian Federation, Municipal Budgetary Institution of State Children's Clinical Hospital 1. (Krasnoyarsk), Public organization "Eurasian Society for infectious diseases", Public organization "Association of Infectious Disease Doctors of St. Petersburg and the Leningrad Region" (AVISPO);
Shcherbakova M.Yu., Belov B.S. A-Streptococcal tonsillitis: modern aspects - State Educational Institution of Higher Professional Education of the Russian State Medical University of Roszdrav, State Institute of Rheumatology of the Russian Academy of Medical Sciences, Moscow.

Sumamed: details about the drug

Azithrimycin is the basic component of Sumamed

Sumamed is a drug that belongs to the group of macrolide antibiotics. It is an azalide that has a prolonged action. It prevents the growth and reproduction of pathogenic bacteria developing in the inflammatory focus.

Gram-positive and gram-negative microorganisms are sensitive to Sumamed. It is particularly effective against staphylococci and streptococci, mycoplasmas, and ureaplasmas.

The antibiotic is available in the following pharmaceutical forms:

Tablets of 125, 250 and 500 milligrams. The tablets are coated with a blue film-like coating. They are convex on both sides and have engraving.
Powder for making syrup, 100 milligrams per 5 milliliters. May have a light yellow or white tint, with a strawberry scent. After the powder dissolves, a homogeneous liquid with a light, slightly yellowish tint is formed.
Powder for forte suspension, 200 milligrams per 5 milliliters. It is characterized by the same properties as the above 100 mg powder. May have a different smell.
Capsules of 250 milligrams. They are gelatin, have a blue cap and a blue body. The capsules contain a light yellow or white powdery substance.

Hypromellose
Corn starch
Calcium hydrogen phosphate
Pregelatinized starch
Magnesium stearate
Polysorbate
Sodium lauryl sulfate
Titanium dioxide
Talc
Dye

More information about antibacterial drugs can be found in the video:

The powder for the syrup contains 200 mg of the active ingredient – azithromycin. It contains the following excipients:

Anhydrous trisodium phosphate
Sucrose
Xanthan gum
Colloidal silicon dioxide
Titanium dioxide
Hyprolose
Hydroxypropyl cellulose
Banana, cherry and vanilla flavors

Additional substances of the drug in capsule form are:

Magnesium stearate
Cellulose in microcrystals
Sodium lauryl sulfate
Titanium dioxide
Indigo carmine
Gelatin

Thus, the composition depends on the form of the drug. The active ingredients are the same, only in certain dosages. Regarding the excipients, they are different for each form of Sumamed.

When an antibiotic is prescribed, contraindications

Sumamed belongs to the latest generation of medicines

Sumamed is prescribed for the following pathological conditions of the respiratory system and otolaryngological diseases:

Sinusitis
Tonsillitis
Angina
Tracheitis
Bronchitis
Bronchotracheitis
Pneumonia
Scarlet fever
Otitis
Laryngitis
Pharyngitis

Widely used for the treatment of inflammatory and infectious diseases of soft tissues and skin, which include:

Impetigo
Secondary dermatoses

In addition, the medicine is used for diseases of the genitourinary system, namely for the treatment of cervicitis, urethritis of various origins, and erythema migrans. Prescribed for Lyme disease.

They treat sexually transmitted pathologies caused by chlamydia with antibiotics.

However, there are some restrictions regarding the use of Sumamed. The antibiotic is contraindicated in case of hypersensitivity to the substances of the drug.

The medicine should be used with caution in case of liver failure and kidney pathologies. This medicine is also used under medical supervision if you are prone to allergic reactions.

Amoxiclav: composition, properties, dosage form

Amoxiclav is an antibacterial combination drug

Amoxiclav is a drug belonging to the group of penicillins with a broad scope of action. This drug is an inhibitor of beta-lactamases of pathogenic bacteria.

Effectively acts against streptococci, staphylococci, enterococci and anaerobic infectious agents and aerobic microorganisms.

This antibiotic is produced in several forms:

Tablets of 250 and 500 milligrams. They are covered with a film-like shell.
Dispersible tablets are called Amoxiclav Quiktab. They are produced in dosages of 875 or 500 milligrams of amoxicillin per 125 milligrams of clavulanic acid.
Powder for suspension, intended for internal use.

The composition of the drug depends on the dosage form of the antibiotic. The active ingredients of the drug are:

Amoxicillin
Clavulanic acid

Excipients of the tablets include croscarmellose sodium and cellulose in microcrystals.

Amoxiclav powder, from which a suspension for oral use is made, contains sodium benzoate, mannitol, sodium citrate, microcrystalline cellulose.

The dispersed tablets contain inactive components: aspartame, talc, castor oil, yellow iron oxide, silicated cellulose in microcrystals, anhydrous colloidal silicon dioxide, flavorings.

Indications and contraindications for use

Antibiotic prescribed for respiratory tract disease

Amoxiclav is widely used in otolaryngological, therapeutic, gynecological, orthopedic practice and in maxillofacial surgery.

Indications for use are the following diseases:

Pneumonia
Chronic bronchitis
Bronchopneumonia
Sinusitis
Retropharyngeal abscess
Otitis media
Chronic tonsillitis
Periodontitis
Chancroid
Cystitis
Cholecystitis
Pyelonephritis
Breast abscess
Gonorrhea
Osteomyelitis

It is often used in the treatment of bacterial infections of the genitourinary system, as well as for pathologies of soft tissues and skin of bacterial origin. Amoxiclav is used to prevent purulent processes and sepsis after surgical interventions on the heart, kidneys, abdominal and pelvic organs.

Contraindications to the use of various forms of the drug include:

Cholestatic jaundice.
Hepatitis of bacterial origin.
Lymphocytic leukemia.
Increasing the body's sensitivity to antibiotic components.
First trimester of pregnancy.

The drug is prescribed with caution and under medical supervision during pregnancy and breastfeeding. It is usually used if the benefit to the woman’s body outweighs the risk of negative effects on the child.

Sumamed or Amoxiclav: what is the difference and which is better?

Each drug has its own composition and properties

Before you find out which of these antibiotics is considered the best, it is important to remember that these drugs are chosen by a qualified specialist, taking into account the individual characteristics of the patient’s body. Therefore, in each case, either of these two drugs may be more effective.

Sometimes, to prevent addiction, the doctor may alternate medications. In case of illness, he first prescribes one medicine, and later uses the next antibiotic for infections.

The differences between these drugs are considered to be related to different groups. Sumamed is a macrolide antibiotic, Amoxiclav belongs to the penicillin series. Depending on this, the main active components of these medications are various substances. Both products are available in tablet form, capsules and suspensions. Amoxiclav is also available in the form of dispersible tablets that quickly dissolve.

The advantage of Sumamed is the duration of its use - only three days.

Therefore, the therapeutic effect occurs faster when taking this antibiotic. However, this drug is significantly inferior to Amoxiclav in the list of contraindications. Sumamed has more restrictions on its use than Amoxiclav. In addition, the list of indications for the use of the latter includes diseases that are not treated with Sumamed. Therefore, it is impossible to clearly determine which drug is better. Since each antibiotic has certain advantages and disadvantages.

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Sumamed and Amoxiclav - different names for the same drug or different medications

Are these drugs used for the same bacterial diseases?

in dental practice;

Why is the duration of treatment with Sumamed and Amoxiclav different for the same pathology?

Which drug is more effective?

If a patient is allergic to Amoxiclav, can Sumamed be used?

Which medications can be used during pregnancy?

Which drug is safer for children?

How to take both antibiotics correctly

What to do if side effects occur from taking Sumamed or Amoxiclav

Which drug is more expensive?

What antibiotics should you take for a sore throat?

Streptococcal bacteria that cause sore throat are more sensitive to penicillin, so quite often the doctor recommends just such drugs.

Amoxicillin is a drug penicillin group. Advantage medicinal product is that it is available in various forms: tablets, syrups, capsules. This is especially convenient for treating young children, who are sometimes quite difficult to give an injection or persuade to take a pill.

Amoxiclav is a form of amoxicillin containing clavulanic acid, which enhances the effect of the drug.

In cases where there is intolerance to penicillin (allergy) or bacteria are insensitive to penicillin, macrolide antibiotics are usually prescribed. Antibiotics of this group are highly effective, low toxic, destroy larger number microorganisms. The first drug in this group is erythromycin, but now the better known drugs are sumamed, zitrolide, and hemomycin, which are analogues of erythromycin.

Titles

If you are not allergic to penicillin, then it is best to use drugs from this particular group, since they are less harmful to the body. Amoxiclav and Amoxicillin show good results.

Amoxiclav is the most effective drug, since it is a new generation antibiotic. However, in some cases it happens that penicillin cannot be used (the causative agent of sore throat is resistant to the substance, allergy to penicillin, etc.), so other broad-spectrum antibiotics are used: Klacid, Lendacin, Sumamed, Cephalexin, Siflox, Erythromycin, Cefazolin.

If you don't start antibacterial treatment with angina, this can lead to serious complications (otitis media, glomerulonephritis, sinusitis).

Antibiotics for angina significantly improve the patient's condition in the first hours after administration. At a very high temperature, you also need to take antipyretics and painkillers, which will help relieve headaches, weakness, etc. It is not recommended to reduce the temperature below 38 degrees with medications, since at this time the body intensively produces antibodies to fight the disease.

Penicillin series

Penicillins were one of the very first antibiotics that people began to use. In modern times, some penicillin drugs have already lost their effectiveness due to bacterial resistance to them, but important advantages that distinguish them favorably from other antibiotics encourage specialists to invent new drugs based on penicillin.

The advantages of these antibiotics include their low harm to the body, wide spectrum of action, and high antibacterial activity. Adverse reactions from penicillin occur much less often than with treatment with other antibiotic drugs. Typically, adverse reactions manifest themselves in the form of allergies, disturbances of intestinal microflora, and sometimes inflammation occurs at the injection site. Penicillin should not be used by people with a tendency to various allergic reactions or with bronchial asthma.

Most drugs of the penicillin group are used only by injection, since the acidic environment of the stomach greatly destroys them and they lose their effectiveness, especially for biosynthetic drugs (produced by biosynthesis). The only exception is phenoxypenicillin, which is resistant to acidic conditions and can be taken orally.

Penicillin drugs should be combined with other drugs with caution; they are contraindicated to be taken simultaneously with certain antibiotics. Penicillins are mainly prescribed for the treatment of diseases caused by gram-positive bacteria (staphylococci, streptococci, pneumococci).

Amoxicillin

Throat diseases caused by bacteria can occur against the background of viral infections or independently, which can lead to severe manifestations of sore throat.

Amoxicillin is often used for bacterial throat infections and sore throats and is a widely used antibiotic.

The antibiotic is effective against large quantity bacteria that cause sore throat. Doctors prescribe amoxicillin as a first-line drug because it is quite effective and has few side effects.

Adverse reactions that may occur when taking amoxicillin include vomiting, diarrhea, and stomach upset. The most severe reactions to the drug are leukopenia, pseudomembranous colitis, agranulocytosis, anaphylactic shock.

Sumamed

Sumamed is pretty strong antibiotic, with a wide spectrum of action and, moreover, this drug is from new developments, which are more effective against bacteria, in comparison with “older” versions of antibiotics.

The drug is available in the form of tablets, suspensions, and injections. You only need to take sumamed for a sore throat once a day, which is quite convenient.

But sumamed has a number of contraindications. Some components of the drug can cause quite severe allergic reactions. When taking the drug, nausea, vomiting, abdominal cramps, and diarrhea may occur, but such reactions are quite rare.

The course of treatment with sumamed usually does not exceed 5 days; for children, the dosage of the drug is determined at the rate of 10 ml of syrup per 1 kg of weight. This dose is designed for three days, after which the dosage is doubled. Take the antibiotic an hour before meals or 2 to 3 hours after meals. Children under 16 years of age are not prescribed the drug by injection.

When treating children, it is important to take pribiotics along with sumamed, which will help preserve the intestinal microflora.

The drug is effective not only for infectious lesion throat, but also for pneumonia, bronchitis, skin diseases, diseases of the genitourinary system, peritonitis.

Before prescribing the drug, the doctor must make a smear to determine the microflora and the susceptibility of bacteria to the drug.

Amoxiclav

Amoxiclav in its antimicrobial action is a unique drug. It is widely used to treat infectious diseases, especially in childhood, starting from three months.

A drug is prescribed if not allergic reactions for penicillin antibiotics, the course of treatment is prescribed by a doctor, individually in each case. The dosage of the antibiotic depends on the age and weight of the child. When taking amoxiclav, relief quickly occurs: the sore throat stops, and the general condition improves.

with their own effective properties the drug is dependent on two active ingredients in its composition (clavulanic acid and amoxicillin), which is why amoxiclav copes better than other drugs.

Flemoxin

Flemoxin effectively fights the inflammatory process and destroys infection. Quite often, flemoxin is used independently, without a doctor’s prescription.

Flemoxin is an antibacterial medicine that can be taken by children of all ages, as well as adults. The drug can also be prescribed during pregnancy.

Flemoxin is a broad-spectrum antibiotic that effectively destroys pathogenic microflora and acts against both gram-positive and gram-negative bacteria. After taking the drug, the maximum concentration in the blood is observed two hours later. Flemoxin is not susceptible to the acidic environment of the stomach; it is excreted from the body by the kidneys in approximately 8–10 hours; in children under one year of age, the removal of the substance occurs twice as fast.

The drug is available in the form of tablets and suspensions. When taking flemoxin, you must strictly observe the dosage hours - the drug must be taken either an hour before a meal, or a couple of hours after a meal. If the disease is mild or moderate severity, then the treatment lasts about a week, more severe conditions require taking the drug for about 10-14 days. The course of treatment should not be interrupted, even if you feel significant relief on the 3rd – 4th day of treatment. It is quite difficult to completely destroy an infection in the body; this requires some time.

The drug is not used for high sensitivity to components for diseases of the kidneys, liver, as well as for infections that are accompanied by inflammation of the lymph nodes.

Flemoxin solutab

A properly selected drug can quickly alleviate the patient’s condition and completely destroy the infection in the body.

For the treatment of sore throat, a semi-synthetic penicillin antibiotic that has a bactericidal effect is widely used. Flemoxin salutab effectively fights staphylococci, which lead to the development of sore throat. The active ingredient of the drug is amoxicillin. Flemoxin salutab is used both for sore throat and for other infectious and inflammatory diseases of the respiratory system, genitourinary system, and skin, which are caused by microorganisms sensitive to the drug.

Flemoxin salutab has good acid resistance; the dosage of the drug is prescribed by the doctor individually, based on the severity of the disease. Typically, for mild to moderate severity of the disease, the course of treatment lasts 5–10 days, in more severe cases – 10–14 days. The drug must be taken even after severe manifestations of the disease (fever, sore throat) have disappeared, otherwise microorganisms will quickly develop resistance to the drug, which will complicate treatment in the future. If there is no improvement in the first 3 to 4 days when taking Flemoxin, it is necessary to replace it with another antibiotic.

Flemoxin salutab is contraindicated in case of infectious mononucleosis, leukemia, or intolerance to some components of the drug.

The use of the drug extremely rarely provokes side effects (nausea, vomiting, diarrhea, allergies).

Augmentin

Augmentin (amoxicillin-clavulanate) is a fairly effective antibacterial agent. The drug is usually used to treat sore throat in childhood. The drug contains two active substances– amoxicillin and clavulanic acid, which sets it apart from others.

Amoxicillin is a semisynthetic antibiotic of the penicillin group, with a broad spectrum of action against large number gram-positive and gram-negative bacteria. Clavulanic acid has a structure similar to penicillin, it effectively eliminates beta-lactamase enzymes produced by pathogenic bacteria to develop antibiotic resistance. It is due to this acid that amoxicillin does not disintegrate under the action of enzymes, which expands its effect on a larger number of bacteria that are resistant to amoxicillin and other drugs of the penicillin group.

Augmentin has all the properties of an antibiotic that has a bactericidal effect on many microorganisms, plus it eliminates the effect of beta-lactamases.

The drug is available in the form of tablets, injections, and suspensions. The dosage in the treatment of children is determined depending on the age and weight of the child.

Cephalexin

Drugs from this group, such as cephalexin, are convenient because they can be taken regardless of meals. It is recommended that an adult patient take no more than 2 g of the drug per day. The dose should be divided into several doses (usually 3 - 4). In severe cases of the disease, the dosage is increased to 4 g per day. In childhood, the dosage depends on body weight and is 25-50 mg per kilogram; the drug should also be divided into several doses. If the disease is severe, the dosage is increased to 100 mg.

Local antibiotics for tonsillitis

Sore throat is common infection, in which severe local inflammation occurs in the pharynx. Use of local therapy in treatment general disease will be ineffective. Treatment of sore throat should be general level: peace, drinking plenty of fluids, antibiotics. Local treatment (irrigation of the throat with aerosols, special absorbable tablets, rinses, etc.) should be added to general treatment to achieve maximum results in treatment.

Is it possible to use bioparox?

Bioparox in the treatment of sore throat can only be used in combination with general treatment. Antibacterial agents for initial stage diseases (before the formation of pus) are the first and main direction in treatment. Typically, bioparox is used extremely rarely in the treatment of sore throat, since there is no need for additional treatment against the background of general therapy.

Bioparox is used for complex treatment chronic tonsillitis(inflammation of the tonsils). The drug is used for no more than 10 days. As when prescribing other antibiotics, it is necessary to determine the susceptibility of pathogens to it. Without such an analysis, treatment of infections with inflammatory processes may lead to severe consequences: complete destruction beneficial microflora in the pharynx, which restrained the proliferation of pathogenic bacteria, after which the microorganisms begin to multiply with greater force, which will lead to severe inflammation.

How to properly use Bioparox for the treatment of chronic tonsillitis?

Bioparox cannot be used uncontrolled. Only a specialist can recommend a drug for treatment. Bioparox helps well in the complex treatment of chronic tonsillitis (inflammation of the tonsils).

It is usually prescribed one session for adults every four hours, for children - every six hours. A session means oral inhalation, which requires a special attachment that is placed on a bottle and located in the oral cavity close to the inflamed tonsils. After this, make two presses to irrigate one tonsil, then two presses for the other. After use, the nozzle must be rinsed in running water.

Antibiotics for sore throat in children

Antibiotics for sore throat in children should be prescribed depending on the cause of the disease: a virus or a streptococcal bacterium. As a rule, no difference is visible upon visual examination; streptococcal bacteria can only be detected by a special test (bacteriological culture).

In some cases, antibiotic treatment can be used in young patients, but this is not always observed positive effect with this treatment. First of all, antibiotics, when destroying the virus, have a detrimental effect on the unformed immune system baby. With a sore throat caused by a viral infection, the body is quite capable of coping on its own; you just need to provide the child with complete rest, plenty of fluids, and adequate vitamin nutrition. If you have streptococcal sore throat, you will most likely need to take a course of antibiotics, which are necessary to prevent the development of more severe complications.

Read more about the use of antibiotics in children here.

Treatment of tonsillitis in adults

Many people are skeptical about antibiotics, believing that the harm they do to the body far outweighs the benefits. This makes some sense, because antibiotics destroy not only pathogenic microorganisms, they also destroy microflora beneficial to our body - as a result, dysbiosis develops. Also, the use of antibiotics can provoke severe allergic reactions.

But, unfortunately, some diseases cannot be cured without the use of antibiotics. Antibiotics for sore throat, especially if pustules appear on the tonsils, the heat, has begun general weakness against the background of intoxication of the body, are simply inevitable. But it is necessary to take antibiotics correctly to reduce possible side effects. The usual course of antibiotic therapy is about 7 days. But many people stop taking the drug as soon as severe symptoms go away to reduce Negative influence on the body from taking antibiotics. This decision is fundamentally wrong and can cause serious complications. Even after the signs of the disease have disappeared (sore throat, weakness, fever), the infection continues to “sit” in the body. If you stop taking the antibiotic, it is possible re-development a disease that will require more serious treatment since microorganisms have already developed resistance to a certain type of antibiotic. Sore throat is often complicated by heart disease and rheumatism, since bacteria spread not only in the main source of inflammation - the throat, but throughout the body and penetrate all organs.

When taking antibiotics, you need to adhere to a certain schedule, otherwise it threatens the development of a severe inflammatory process. In this case, you will need to use drugs whose negative effect on the body will be much stronger.

To reduce Negative consequences when taking antibiotics, it must be taken from the first days of treatment special drugs to restore intestinal microflora and liver.

Duration and scheme of treatment for various forms of tonsillitis

The course of treatment with antibiotic drugs depends on the drug, the stage of the disease, the severity of the process, the state of the person’s immunity, etc. The average course of treatment is 10 days.

For mild to moderate forms of sore throat, antibiotics are recommended to be taken for 5-7 days. In more severe cases, it is recommended to continue treatment for up to 10-14 days.

Antibiotic treatment should not be stopped after the condition has improved, the temperature has dropped, and the sore throat has disappeared. It is extremely important to complete the full course of antibiotic treatment so that the infection in the body is completely destroyed.

This is necessary, first of all, to prevent relapses of the disease. With untreated sore throat, there is a risk of repeated inflammation in the body, but pathogenic bacteria in this case will already develop resistance to a certain group of antibiotics, and a change in drug and a second course of treatment will be required. Also, sore throat can be complicated by quite severe heart diseases, rheumatism.

In any case, you need to take the medicine as much as prescribed by the doctor. You cannot change the dosage or duration of treatment on your own.

Purulent sore throat

Sore throat can appear at any age; usually one tonsil is affected more than the other. If a sore throat is not treated, it can develop into purulent form and be aggravated by severe heart complications.

With purulent sore throat appear severe pain in the throat, which intensify over time, swallowing is difficult, and the temperature rises (sometimes to very high levels). The tonsils become bright red, with whitish purulent foci. The submandibular lymph nodes also swell.

Complex treatment also includes the prescription of antibiotics for sore throat, which has acquired a purulent form. Drugs from the group of penicillins and cephalosporins are prescribed.

The most effective against sore throat pathogens (group A streptococci) are penicillin drugs, which must be taken for 10 days. For purulent sore throat, other penicillin drugs can be used, such as augmentin, azithromycin, ampicillin.

Amoxicillin is a synthetic derivative of penicillin. It does not destroy bacteria, but stops their growth by destroying cell walls.

Antibiotics of the cephalosporin group are similar in chemical composition for penicillin drugs. The antibiotic Cephalexin interferes with the formation of the cell wall, which is necessary for the survival of bacteria, which ultimately leads to their death.

Erythromycin and tetracycline are used in case of allergic reactions to penicillin and its derivatives. Erythromycin is a broad-spectrum antibiotic that is effective against a variety of bacteria. Its antibacterial activity is similar to penicillin, making it a good alternative for people intolerant to penicillin.

Tetracycline disrupts protein synthesis, which prevents bacterial growth. This drug is used for penicillin intolerance to treat most bacterial infections.

Read the full article about the names and method of using antibiotics for purulent sore throat here.

Follicular tonsillitis

Follicular tonsillitis affects the almond follicles; outwardly you can see their strong enlargement and swelling. Viewing purulent follicles, which may be white or dirty yellow (depending on the duration of the disease). The pustules are small in size - approximately 1 - 2 mm. After the pustules break through, a whitish coating appears on the tonsils.

The causative agent of the disease is most often streptococcal or pneumococcal infection. Disease develops if there is a decrease protective forces body, hypothermia, infection in the oral cavity. Follicular tonsillitis can affect both adults and children, but in childhood the disease occurs most often and has some characteristics. The disease mainly develops during the cold season – autumn-winter.

When treating follicular tonsillitis, it is necessary not only to destroy the infection in the body, but also to remove intoxication. At the first signs of the disease, you must follow bed rest and drink more fluids. So as not to irritate sore throat You need to eat mostly liquid food, in small portions.

The modern pharmaceutical industry offers a large selection of drugs for the treatment of infectious diseases, both in adults and young children.

The most common drugs for the treatment of sore throat are Erythromycin, Flemoxin, Sumamed, Ampicillin, etc. The course of antibiotic treatment is approximately 10 days. You can also use local drugs to relieve sore throat: orasept, faringo-spray, etc. Spruces appeared skin rashes(allergy), you can take antihistamines (suprastin, diazolin, loratidine, etc.). Also, do not forget to protect your intestines from the harmful effects of antibiotics. As a rule, it is recommended to take Linex to normalize microflora.

Lacunar tonsillitis

Lacunar tonsillitis is a widespread disease today. The disease mainly affects the upper respiratory tract, but if the tonsils are not affected, then the inflammation process is located directly in the throat. If there are no tonsils (surgically removed) or they are damaged, lacunar tonsillitis is a short time gives a serious complication - pneumonia.

Taking drugs with a broad spectrum of action should begin with the appearance of the first signs of the disease. If you conduct a culture test to determine the susceptibility of pathogenic microflora to antibiotics, the treatment process will be much more effective. The human body is able to overcome the main symptoms of the disease in a week, but the infection will remain inside, and every time under favorable conditions external factors(decreased immunity, hypothermia, etc.) will provoke a sore throat. As a result, frequent illnesses will lead to severe complications - rheumatism, disability. Therefore, it is extremely important to choose an effective course of treatment that will help eliminate possible problems with health.

At the onset of the disease, it is recommended to take broad-spectrum antibiotics, cephalosporins and sulfonamides. For example, at the first signs of the disease, it is good to take one tablet of sumamed per day or one tablet of ciprolet twice a day. An appointment is also required. antihistamines(suprastin, diazolin, pipolfen) to relieve swelling of the tonsils and facilitate swallowing.

To strengthen the immune system, vitamin C is prescribed up to 1 g per day. A good remedy for angina is ascorutin, which contains rutin and ascorbic acid. This drug not only increases the body's resistance to infections, but also strengthens the vascular walls, which will prevent DIC syndrome.

Herpangina

Herpangina is an extremely contagious acute viral disease, which is caused by microorganisms of the enterovirus family, Coxsackie. At the beginning of the disease, a high temperature rises (up to 40 degrees), a sore throat, aching joints, and headaches appear. Sometimes vomiting and diarrhea appear. On soft palate, tonsils, back wall small bubbles appear in the pharynx, which open after a few days and recovery begins.

Antibiotics for this form of angina are ineffective. Treatment is mainly aimed at relieving the symptoms of the disease. Usually prescribed gargling, antipyretics, rest and plenty of fluids.

Catarrhal sore throat

Catarrhal tonsillitis usually occurs when the body's defenses are weakened (lack of vitamins, hypothermia, etc.). Most often, the disease develops in late winter and early spring. Also, catarrhal sore throat is provoked by microorganisms that live on the mucous membrane of the pharynx and upper respiratory tract. If the diagnosis is made correctly and effective treatment is started, severe manifestations of the disease usually disappear within a few days. Treatment is usually prescribed at home (hospitalization is only for very severe conditions).

Antibiotics for angina are prescribed with a broad spectrum of action - Bactrim, Augmentin, erythromycin, streptocide. For effective treatment These drugs must be taken for at least 7 days, otherwise the infection remains in the body in a “dormant” state and can cause serious complications. Can be used to treat sore throat local therapy to relieve sore throat - gargling, irrigation with special aerosols, absorbable tablets, etc. With catarrhal tonsillitis, the lymph nodes can become inflamed, usually no treatment is required, so when the infection is destroyed in the body, the lymph nodes return to normal on their own.

Viral sore throat

Antibiotics for sore throat caused by viruses are ineffective. Transmission of the virus occurs through airborne droplets - when sneezing, coughing, through personal items - telephone, handkerchief, dishes, toys, etc. Treatment of sore throat in this case consists of reducing the symptoms of the disease - fever, sore throat, weakness. Antipyretic and restorative drugs are usually prescribed. To reduce swelling and sore throat, rinsing with herbal decoctions (chamomile, sage, eucalyptus), and special absorbable tablets (pharyngosept, neoangin, etc.) are helpful.

Sore throat without fever

Common symptoms of sore throat are considered to be a sore throat and high temperature (up to 40 degrees). But there are cases when a sore throat occurs without an increase in body temperature. This usually happens with catarrhal tonsillitis, when only the surface of the tonsils is affected, there is no purulent plaque.

But the absence of fever does not mean that measures should not be taken to combat the disease. It is necessary, as with other forms of sore throat, to remain in bed and gargle to facilitate swallowing (a solution of salt and baking soda, herbal decoctions are good). It is recommended to drink plenty of fluids to prevent dehydration and remove bacterial breakdown products.

Antibiotics for angina, even if there is no fever, are prescribed with a broad spectrum of action, mainly of the penicillin group (amoxicillin, ampicillin).

Streptococcal sore throat

Streptococcal tonsillitis occurs mainly in childhood. Streptococcal infection does not affect the palatine tonsils, but the disease causes high fever, weakness, enlargement lymph nodes. The causative agent of the disease, as the name suggests, is streptococcal bacteria. The disease can be transmitted from a carrier of the infection (who may not even be aware of it) or from a sick person through airborne droplets. It usually takes several days from the moment of infection to the onset of symptoms; the disease progresses in mild form and it looks like acute respiratory infections.

Antibacterial agents active against streptococci are prescribed: cephalexin, amoxicillin, cefuroxime, cefprozil, etc. For allergic reactions, erythromycin is prescribed. The duration of treatment should be strictly observed; treatment should not be interrupted independently, even after all symptoms have disappeared.

The purpose of prescribing antibiotics is to reduce possible complications tonsillitis.

The drugs that we will consider in this article are antibacterial agents, which means they are capable of destroying pathogenic microflora.

These antibiotics have found their use not only for the treatment of infections of the respiratory system, but are also successfully used for all organs and systems of the body where pathogenic microorganisms have settled.

Briefly about the correct choice of antibiotics

Some antibacterial agents are weaker, while others, on the contrary, have a more pronounced effect. In the treatment of infectious diseases there are certain rules, or the so-called hierarchy (its own order) of prescribing antibiotics.

In pediatric practice, in principle, as in adults, treatment always begins with penicillins: Augmentin, Amoxiclav, Amoxicillin. Parents often ask the question: “Which antibiotic should I choose for my child, which will work better and more effectively?” It is immediately worth noting that the selection antibacterial agents Only the doctor does.

The ideal prescription of all antibiotics is considered to be a targeted choice of drug according to the results of bacterial culture together with an antibiogram, which clearly shows what caused the disease and what drugs the bacterium is sensitive to. This approach is “hit the mark.”

Many patients have repeatedly encountered the fact that after prescribing antibacterial therapy, the effect did not occur or was unsatisfactorily insignificant. This was followed by subsequent replacement with drugs from another group, and usually such treatment gave positive results.

If we talk about the pathology of the respiratory system, the drugs that we will consider below are considered the most popular in this field of medicine.

To answer the question about the choice of antibiotics between amoxiclav, augmentin, summed and amoxicillin (which is better?), we will conduct short review these drugs, and find out their features.

Amoxicillin (Russia, Serbia, Vietnam)

The active ingredient of Amoxicillin is amoxicillin trihydrate. The drug belongs to the semi-synthetic penicillins with a broad spectrum of action. Shows high activity against some gram-positive and gram-negative aerobic bacteria: It is practically not exposed to the acidic environment of the gastrointestinal tract and is quickly absorbed through the intestinal walls.

A number of bacteria produce penicillinase, which has a detrimental effect on Amoxicillin, as a result of which microorganisms become resistant to this antibiotic.

The drug is available in capsules, tablets and powder for suspension.. All forms are intended for internal reception, Amoxicillin is not used for injection.

Amoxicillin is used from the first days of a child’s life, even in premature babies. The calculation of the drug for the youngest patients is based on 20 mg/kg of the baby’s weight. The dose and frequency of administration for newborns are selected by neonatologists.

Main indications for the use of Amoxicillin

The list of indications is quite long:

tonsillitis;
pharyngitis;
laryngitis;
otitis;
angina;
bronchitis;
tracheitis;
frontal sinusitis;
sinusitis;
pneumonia;
meningitis;
endometritis;
erysipelas;
sepsis;
leptospirosis.

Contraindications

Amoxicillin should not be taken in the following cases:

allergic reactions to penicillins and cephalosporins;
intolerance to one of the components of Amoxicillin;
ARVI;
lymphocytic leukemia;
severe gastrointestinal diseases;
Infectious mononucleosis;
bronchial asthma, especially severe;
hay fever;
lactation period, pregnancy (relative contraindication - Amoxicillin is prescribed if necessary);
intestinal dysbiosis.

Side effects

Taking the drug is sometimes accompanied by adverse reactions:

nausea;
violation of taste;
diarrhea;
glossitis;
vomiting (rare);
headache;
conjunctivitis;
hives;
anaphylactic shock (extremely rare);
joint pain;
insomnia;
anxiety;
ataxia;
convulsions;
candidiasis;
the drug reduces the effect of contraceptives.

Amoxicillin price for capsules 500 mg 20 pieces (Russia) - 80 rubles, the cost of tablets 500 mg No. 20 (Russia) is 52 rubles, granules for oral suspension 250 mg (Serbia) are estimated at approximately 95 rubles.

Amoxiclav (Slovenia)

The drug belongs to the penicillin series, and is effective against a large number of bacteria (according to the original current instructions). The active ingredients are amoxicillin trihydrate and clavulanic acid (potassium clavulanate).

Amoxiclav is available in tablet form, powder for preparing a medicinal suspension (orally) and injection solution. Tablets are used after 12 years, and when the patient's weight is at least 40 kg. The powder (suspension) is popular in pediatrics and is allowed from the first days of a child’s life.

Main indications for use of Amoxiclav

The antibiotic is used for the following infectious processes:

sinusitis (acute and chronic);
tonsillitis, tonsillopharyngitis;
pharyngitis;
otitis;
bronchitis;
tracheobronchitis;
frontal sinusitis;
nasopharyngitis;
sinusitis (ICD-10 - classification);
pneumonia;
pleural empyema;
pleurisy;
skin, gynecological, genitourinary, bone and other infections.

Contraindications

The drug should not be used in the following cases:

allergic reactions to beta-lactam antibiotics (cephalosporins, penicillins, others);
mononucleosis and during the diagnosis of this disease;
cholestatic jaundice and liver reaction to Amoxiclav;
intolerance to one of the components of Amoxiclav;
lymphocytic leukemia;
severe liver and kidney diseases;
pseudomembranous colitis (relative contraindication, prescribed with caution).

Pregnancy and lactation - the decision to prescribe Amoxiclav is made only according to strict indications.

Side effects

When taking the drug, side effects are usually insignificant. In most cases, Amoxiclav is well tolerated by patients, but the possibility of adverse reactions is not excluded, they are as follows:

nausea;
diarrhea;
vomiting (extremely rare);
headache;
hives;
allergies;
disturbances in blood parameters (thrombocytopenia, increased liver function tests - ALT, AST, eosinophilia, others);
insomnia;
candidiasis;
other.

Price for Amoxiclav tablets 250 mg (15 pieces) is 230 rubles, the cost of powder for a 250 mg suspension is 280 rubles.

Amoxicillin or Amoxiclav – which is better to choose?

Both drugs belong to the penicillin series and contain amoxicillin, but Amoxiclav is supplemented with clavulanic acid, thanks to which it significantly expands the spectrum of action. Therefore, Amoxiclav is indicated for more severe infections. Amoxicillin is “unarmed” against beta-lactomases, and this is its disadvantage.

The only advantage of Amoxicillin is its cost, it is much cheaper than Amoxiclav.

When choosing these two funds, we can conclude: it is better to overpay for more reliable drug, than then look for analogues, which will still be more expensive. Although it is not a fact that Amoxicillin will be perfect and will solve the problem with pathogenic microorganisms, and even at minimal cost.

Augmentin or Amoxiclav?

Augmentin is a structural analogue of Amoxiclav. They are completely similar in composition, indications, contraindications and other parameters. Therefore, to answer the frequently asked question: “Which is better – Augmentin or Amoxiclav?” is not difficult.

These antibiotics differ only in the manufacturer and a slight difference in price. The tablets cost approximately the same, and the powder for preparing the suspension from Augmentin is slightly cheaper - 150 rubles.

Some doctors prefer to use Augmentin more often for children, others do not see the point in comparison at all. In order not to rack your brains, entrust the choice of drug and treatment to your doctor.

Sumamed (Croatia)

Sumamed does not belong to the penicillins, like all the previous antibiotics under consideration, but belongs to the macrolides (azalide). The active ingredient is azithromycin dihydrate. The drug is produced in the form of capsules, tablets and granular powder from which an aromatic suspension with banana and cherry flavors is prepared.

The drug has a pronounced antimicrobial effect due to the ability to suppress bacterial cell protein synthesis. Penetrating intracellularly, Sumamed quickly destroys pathogenic flora. It is active against a wide range of pathogenic microorganisms.

It is better to prescribe this antibiotic after an antibiogram, due to the fact that there are a number of bacteria that are already initially resistant to it, for example, Staphylococcus spp. or Bacteroides fragilis.

Indications

The drug can be used in cases where the following diseases are sensitive to Sumamed, namely:

Diseases of all parts of the respiratory system:

sinusitis;
otitis (acute and catarrhal);
pharyngitis;
tonsillitis;
tracheitis;
bronchitis;
pleurisy;
bronchopneumonia.

Infectious diseases of the skin:

impetigo;
pyoderma;
erysipelas;
streptoderma;
acne.

Genitourinary pathologies:

cystitis;
pyelonephritis;
pyelitis;
kidney stone disease complicated by bacteria;
glomerulonephritis;
urethritis.

When is Sumamed not used?

The following factors are exceptions to taking the drug:

individual intolerance to the composition of the product;
renal and liver failure;
age of children for different forms the drug is limited (tablets - up to 3 years, capsules - up to twelve years, provided that body weight is not lower than 45 kg, for suspension - up to 6 months);
not taken with ergotamine (alkoloid) and dihydroergotamine (alpha blocker).

Relative contraindications:

arrhythmias;
myasthenia gravis;
bradycardia;
pregnancy and lactation;
severe heart diseases of organic nature.

Side effects

The following side effects are possible while taking Sumamed:

itchy skin;
hives;
candidiasis;
pseudomembranous colitis;
changes in blood parameters;
anaphylactic shock;
headache;
insomnia;
rave;
fainting;
impairment of smell, vision, hearing.
noise in ears;
tachycardia;
dyspnea.

The most interesting thing is that doctors consider Sumamed a very effective and safe drug, despite its huge list of “side effects” (see original instructions).

In practice, the remedy really works great, even a disease such as dry pleurisy goes away in three days. Short courses of therapy, as a rule, do not entail side effects.

Price for Sumamed depends on the form and dose of the drug, for example, capsules (250 mg) No. 6 cost 460 rubles, tablets (500 mg) No. 3 - 430 rubles, powder for suspension - 200 rubles.

Sumamed or Amoxiclav – which works better?

These drugs are completely different, belong to different groups, differ in their main active substance. Amoxiclav is allowed to be used from the first months of life, Sumamed - from 6 months. Amoxiclav is cheaper, but Sumamed has short courses of treatment. It is usually prescribed for 3 days, and penicillins are taken for a week. The speed of action of Sumamed reduces the duration of the disease.

It is impossible to clearly say which drug is better, everything is individual. Each drug has its own advantages and disadvantages, and only the experience of a doctor will help suggest the right choice.

Antibiotics for sore throat

Often on Internet pages, patients ask questions about the treatment of certain diseases with antibiotics, in particular: “What is better to choose for a sore throat, which antibiotic will help quickly?”

Of course, this question cannot be answered unequivocally. Sore throat is an infectious disease caused by bacteria, most often streptococci or staphylococci. The disease can have a catarrhal form (mild) and more severe manifestations (follicular, lacunar, herpetic or necrotizing tonsillitis, up to the development of a retropharyngeal abscess).

Depending on the picture of the disease and the culture data obtained, an antibiotic is selected. They try to start treatment with penicillins (Augmentin, Amoxiclav), and if they are ineffective, they switch to macrolides (Azithromycin, Sumamed) or cephalosporins (Cefalexin, Cefatoxime, Cefazolin, Ceftriaxone).

Azithromycin is very often used in pediatric practice, but for successful treatment need to know correct instructions use of azothromycin for children.

Independent selection of antibacterial agents is excluded due to the danger of the emergence of resistant (resistant) forms of the disease. Complex treatment sore throats, where antibiotics play a leading role, eliminate infectious process within five days and give a chance to exclude recurrence of the disease in the future. Be healthy!

How to treat a sore throat with antibiotics from Doctor Komarovsky

Attention, TODAY only!

Usually, for various bacterial infections, antibiotics belonging to a specific group are prescribed. Effective and widely used drugs are Amoxiclav and Sumamed.

Azithrimycin is the basic component of Sumamed

Gram-positive and gram-negative microorganisms are sensitive to Sumamed. It is particularly effective against staphylococci and streptococci, mycoplasmas, and ureaplasmas.

The antibiotic is available in the following pharmaceutical forms:

Tablets of 125, 250 and 500 milligrams. The tablets are coated with a blue film-like coating. They are convex on both sides and have engraving.
Powder for making syrup, 100 milligrams per 5 milliliters. May have a light yellow or white tint, with a strawberry scent. After the powder dissolves, a homogeneous liquid with a light, slightly yellowish tint is formed.
Powder for forte suspension, 200 milligrams per 5 milliliters. It is characterized by the same properties as the above 100 mg powder. May have a different smell.
Capsules of 250 milligrams. They are gelatin, have a blue cap and a blue body. The capsules contain a light yellow or white powdery substance.

Hypromellose
Corn starch
Calcium hydrogen phosphate
Pregelatinized starch
Magnesium stearate
Polysorbate
Sodium lauryl sulfate
Titanium dioxide
Talc
Dye

More information about antibacterial drugs can be found in the video:

The powder for the syrup contains 200 mg of the active ingredient – azithromycin. It contains the following excipients:

Anhydrous trisodium phosphate
Sucrose
Xanthan gum
Colloidal silicon dioxide
Titanium dioxide
Hyprolose
Hydroxypropyl cellulose
Banana, cherry and vanilla flavors

Additional substances of the drug in capsule form are:

Magnesium stearate
Cellulose in microcrystals
Sodium lauryl sulfate
Titanium dioxide
Indigo carmine
Gelatin

Thus, the composition depends on the form of the drug. The active ingredients are the same, only in certain dosages. Regarding the excipients, they are different for each form of Sumamed.

Sumamed belongs to the latest generation of medicines

Sumamed is prescribed for the following pathological conditions of the respiratory system and otolaryngological diseases:

Sinusitis
Tonsillitis
Angina
Tracheitis
Bronchitis
Bronchotracheitis
Pneumonia
Scarlet fever
Otitis
Laryngitis
Pharyngitis

Widely used for the treatment of inflammatory and infectious diseases of soft tissues and skin, which include:

Impetigo
Secondary dermatoses

In addition, the medicine is used for diseases of the genitourinary system, namely for the treatment of cervicitis, urethritis of various origins, and erythema migrans. Prescribed for Lyme disease.

They treat sexually transmitted pathologies caused by chlamydia with antibiotics.

However, there are some restrictions regarding the use of Sumamed. The antibiotic is contraindicated in case of hypersensitivity to the substances of the drug.

The medicine should be used with caution in case of liver failure and kidney pathologies. This medicine is also used under medical supervision if you are prone to allergic reactions.

Amoxiclav is an antibacterial combination drug

Amoxiclav is a drug belonging to the group of penicillins with a broad scope of action. This drug is an inhibitor of beta-lactamases of pathogenic bacteria.

Effectively acts against streptococci, staphylococci, enterococci and anaerobic infectious agents and aerobic microorganisms.

This antibiotic is produced in several forms:

Tablets of 250 and 500 milligrams. They are covered with a film-like shell.
Dispersible tablets are called Amoxiclav Quiktab. They are produced in dosages of 875 or 500 milligrams of amoxicillin per 125 milligrams of clavulanic acid.
Powder for suspension, intended for internal use.

The composition of the drug depends on the dosage form of the antibiotic. The active ingredients of the drug are:

Amoxicillin
Clavulanic acid

Excipients of the tablets include croscarmellose sodium and cellulose in microcrystals.

Amoxiclav powder, from which a suspension for oral use is made, contains sodium benzoate, mannitol, sodium citrate, microcrystalline cellulose.

The dispersed tablets contain inactive components: aspartame, talc, castor oil, yellow iron oxide, silicated cellulose in microcrystals, anhydrous colloidal silicon dioxide, flavorings.

Antibiotic prescribed for respiratory tract disease

Amoxiclav is widely used in otolaryngological, therapeutic, gynecological, orthopedic practice and in maxillofacial surgery.

Indications for use are the following diseases:

Pneumonia
Chronic bronchitis
Bronchopneumonia
Sinusitis
Retropharyngeal abscess
Otitis media
Chronic tonsillitis
Periodontitis
Chancroid
Cystitis
Cholecystitis
Pyelonephritis
Breast abscess
Gonorrhea
Osteomyelitis

Contraindications to the use of various forms of the drug include:

Cholestatic jaundice.
Hepatitis of bacterial origin.
Lymphocytic leukemia.
Increasing the body's sensitivity to antibiotic components.
First trimester of pregnancy.

Each drug has its own composition and properties

Sometimes, to prevent addiction, the doctor may alternate medications. In case of illness, he first prescribes one medicine, and later uses the next antibiotic for infections.

The advantage of Sumamed is the duration of its use - only three days.

High susceptibility to diseases of the upper respiratory tract is far from uncommon in our time. Unpleasant symptoms of infections cause a lot of discomfort. In addition, if not properly treated, such diseases lead to complications that make the situation even worse. Often, antibiotics such as amoxiclav, sumamed and augmentin are used to treat serious diseases (various forms of sinusitis).

allergic manifestations to the components of the drug;
mononucleosis and suspicions of it;
jaundice;
lymphocytic leukemia

deterioration of the digestive system;
nausea and gag reflexes;
liver dysfunction;
development of jaundice;
allergic manifestations (itching, rash, irritation, etc.);
development of diseases of the circulatory system;
migraine;
dizziness;
convulsions;
urinary disturbance.

The antibiotic belongs to the group of macrolides and can be prescribed when the patient does not accept penicillins. It is noteworthy that sumamed is considered a fairly safe drug. It can be used for a long time. Although such a need is not always required. Typically, the course of macrolides does not exceed 3 days.

Although sumamed belongs to the latest generation of drugs, it cannot be used by everyone. It is worth noting that the list of prohibitions is quite small. In this regard, the drug is clearly better than the penicillin group. So, sumamed is contraindicated for:

pregnancy;
lactation period;
infancy;
intolerance to azithromycin.

feeling of nausea;
vomiting reflex;
skin rashes.

Since agumentin is a copy of amoxiclav, the contraindications will be absolutely the same. The wide list of side effects also remains unchanged. You need to remember this when buying Augmentin. And, of course, it is not recommended to prescribe the drug yourself, as the risk of side effects increases.

Among the evaluation criteria, it is necessary to focus on the duration of treatment. This is a very important indicator, especially when they begin to treat young children. Here augmentin or amoxiclav are clearly inferior. They need to be taken for a week, while the duration of taking sumamed is reduced to 3 days. Consequently, the drug acts faster and recovery occurs earlier.

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“Sumamed and Amoxiclav, as far as I know, are widely used for the treatment bacterial infection various organs and systems. They have worked well for a long time. But I’m most interested in what is prescribed first for angina - Sumamed or Amoxiclav? What is the difference between these antibacterial drugs? Why do different doctors give preference to Amoxiclav for certain pathologies, and Sumamed for others?”

Sumamed and Amoxiclav belong to different groups of antibacterial drugs and there are many differences between them. The active ingredient of Sumamed is azithromycin, an antibiotic from a number of macrolides.

This drug has a pronounced bacteriostatic effect, which is realized by inhibiting protein synthesis in microbial cells. This makes it impossible for them to reproduce further and makes them more sensitive to the body’s protective immune mechanisms.

Amoxiclav consists of the penicillin antibiotic amoxicillin and the penicillinase inhibitor clavulanic acid. This combined bacterial agent has a bactericidal effect on microbes. Amoxicillin is capable of disrupting the integrity of the cell membranes of pathogenic flora, which leads to their death. Clavulanic acid protects the antibiotic from the protective mechanism of many bacteria - the synthesis of special enzymes that break down amoxicillin. This significantly expands the range possible destination antibacterial medicine.

Patients often confuse Sumamed and Amoxiclav because of the similar names of the active ingredients, and also because they are prescribed for the same pathologies.

The list of indications for Amoxiclav and Sumamed is largely similar, but there are a number of significant differences. They are due to the fact that azithromycin preparations are more selective for certain types of tissue in which they accumulate. Therefore, Sumamed is primarily used for pathologies of the following tissues and organ systems:

respiratory tract (bronchitis, pneumonia, laryngitis, pleurisy);
ENT organs (sinusitis, otitis, pharyngitis, tonsillitis);
skin (erysipelas, erythema migrans);
genitourinary system (chlamydia).

Amoxiclav, due to its less selective penetration of amoxicillin and accumulation in body tissues, creates a therapeutic concentration in a large number of organs. Therefore, this antibiotic has a wider scope of use. It can, in addition to the above-mentioned pathologies, be used for bacterial pathologies:

in dental practice;
internal female genital organs (vagina, uterus, fallopian tubes, ovaries);
gallbladder and bile ducts (cholecystitis, cholangitis);
digestive system (gastritis, duodenitis, enteritis, colitis);
soft, connective tissues and musculoskeletal system.

This is due to the pharmacological characteristics of antibiotic metabolism. Sumamed has the ability to accumulate in peripheral tissues of the body. It also passes into the focus of inflammation, where its concentration can be 10-30 times higher than the amount of azithromycin in the peripheral blood.

After last appointment the drug, its therapeutic dose remains in the tissues for about 72 hours.

In Amoxiclav, metabolism occurs in a different way. Amoxicillin penetrates body tissues much worse. At the same time it happens rapid elimination antibiotic through the kidneys. Therefore, to maintain therapeutic concentrations in the blood, it is necessary to regularly take new doses of the drug.

Typically, the duration of treatment with Sumamed is 2-3 days shorter than with Amoxiclav.

It is impossible to say for sure which is better - Sumamed or Amoxiclav. It all depends on the type and strain of bacterial infection that has affected the patient’s body. However, extensive research has been conducted for about 20 years on the issue of antibiotic resistance of bacteria to these drugs.

In recent years, there has been an increase in the frequency of strains of microorganisms that have become invulnerable to penicillin antibiotics. Resistance to macrolides remains at a relatively low level, which allows them to be actively prescribed if necessary in inpatient or outpatient practice. However, it should be taken into account that these studies were carried out mainly on bacterial pathogens of respiratory tract diseases.

Which of these two drugs is less likely to cause side effects?
First, it should be noted that both Sumamed and Amoxiclav belong to the group of antibiotics, when taken, severe side effects with damage to important systems of the patient’s body occur relatively rarely.

Both drugs are characterized by the development in a fairly large proportion of patients of dyspeptic symptoms (feelings of heaviness in the abdomen, nausea, vomiting, diarrhea) during therapy.

It is also possible that a superinfection may occur, especially against the background long-term use antibiotics.

Since Amoxiclav is a beta-latcam antibacterial agent, a fairly significant part of the population (5-7%) has hypersensitivity to it. It is manifested by the development of allergic reactions of varying severity (rash, Quincke's edema, anaphylactic shock). Sometimes there is also a toxic effect of amoxicillin on the central nervous system with the development of headache, dizziness, parasthesia.

There is a wider range of possible side effects when taking Sumamed, but at the same time they occur sporadically. Since it undergoes metabolism in the liver, it cannot be used for chronic inflammatory and oncological pathologies of this organ. This can lead to the development of chronic functional liver failure.

Sumamed also has the ability to prolong ventricular repolarization, which sometimes leads to the development of cardiac tachyarrhythmias and disruption of the normal rhythm. Therefore, the drug should not be prescribed for indirect signs susceptibility to this complication (prolongation of the QT interval on the electrocardiogram).

Also, the use of azithromycin provokes exacerbations of myasthenia gravis, so it should not be used by patients who are undergoing therapy for this pathology.

The most serious side effect that can occur when taking Sumamed is impaired renal function. It has been proven in clinical experiments that the drug reduces the glomerular filtration rate, which leads to an increase in the concentration of creatinine and urea in the blood plasma.

In most cases, these changes are reversible and disappear after the end of therapy, but sometimes they develop into interstitial nephritis.

Thus, side effects are less common when taking Sumamed. But if the patient does not have hypersensitivity to beta-lactam antibiotics, then it is safer to prescribe Amoxiclav.

The answer is clear - yes, it is possible. An allergy to Amoxiclav is caused by the body's hypersensitivity to a beta-lactam compound. The latter include penicillins, cephalosporins, monobactams and carbapenems. If there is a history of allergic reactions to any of the drugs in these groups, it is necessary to prescribe another antibiotic with a completely different molecule structure.

This is especially important for children with allergic diathesis and a tendency to develop angioedema and anaphylactic shock.

According to modern recommendations for the treatment of bacterial pathologies, macrolides are the drugs of choice in this situation. They have absolutely no cross-reactions with penicillins, which makes Sumamed a safe treatment option for patients allergic to Amoxiclav.

During pregnancy and lactation, it is recommended to prescribe Amoxiclav. This is primarily due to the lower teratogenic effect that all penicillin antibacterial drugs have. The American FDA has given Amoxiclav category B, which indicates that this drug can be taken during pregnancy and that there is no evidence of toxic effects on the fetus.

Azithromycin, which is the active ingredient of Sumamed, penetrates into the bloodstream of the fetus in small quantities, which makes it possible to assume its possible negative effect on it.

Therefore, this drug should be prescribed in situations during pregnancy when the potential benefit of the prescription significantly outweighs the harm.

Both Sumamed and Amoxiclav are safe drugs for children of any age, starting from the first month of life. They are recommended for use in pediatric practice by the world's leading specialized associations of doctors.

Long-term use of the drugs has shown that the incidence of side effects in children does not differ significantly from adults. However, before the first use of Amoxiclav, it is recommended to test for hypersensitivity to the drug.

Manufacturers produce antibiotics in syrup form especially for children. This helps to accurately dose the required amount of the drug, depending on the age and body weight of the child.

Antibiotics are classified as systemic drugs, which affect various systems in the patient’s body. Therefore, you should not self-medicate and take Amoxiclav or Sumamed without a prescription from a qualified doctor.

As practice shows, ignoring this simple rule often leads to the development of complications, side effects and lack of clinical effect from taking medication.

Another negative effect is the emergence of antibiotic-resistant strains of bacteria, for the treatment of which it is necessary to use other groups of drugs.

Evaluation of the effectiveness of antibiotic use is usually carried out 48-72 hours after the start of therapy. Changes in body temperature are taken into account, general analysis blood and patient's condition. If the dynamics are positive, treatment with the selected drug continues. If there is no desired effect, the antibiotic must be changed.

It is necessary to take the antibiotic at the same time of day to ensure sufficient concentration in the blood. If you miss a dose, you should take the dose of the drug as quickly as possible, and then continue the course of therapy as usual.

You can take the tablet or syrup of the drug only with plain water. You cannot use soda, dairy products, coffee or strong tea for this purpose, as they can change the processes of absorption and metabolism of the antibiotic, which negatively affects the results of treatment.

Stop the antibiotic yourself at the first signs of improvement general condition also not recommended.

This can provoke the development of bacterial resistance to the drug, as well as recurrence of the disease. Only the attending physician has the right to cancel Sumamed or Amoxiclav.

If you experience any side effects from taking these antibiotics, you should immediately contact your medical staff or your doctor.

At the same time, it is necessary to understand that their mere presence does not constitute absolute indication to discontinuation of the drug.

Dyspeptic symptoms, headaches, a slight increase in the concentration of creatinine or liver enzymes in the blood plasma can be not only a consequence of taking the medication, but also the bacterial pathology itself. If their occurrence is due precisely to the use of antibiotics, then in almost all cases these symptoms quickly disappear after the end of the course of therapy.

Sumamed - branded antibacterial drug Croatian pharmaceutical company Pliva, which first synthesized it in 1980. Amoxiclav is a generic, which is produced by the Slovenian company Lek. This is why Sumamed in retail pharmacy chains is slightly more expensive than Amoxiclav.

It is impossible to say unequivocally what is better for angina - Amoxiclav or Sumamed. Both drugs are very effective, both help in about 95% of cases. The frequency and severity of the side effects they cause are approximately the same, both are available in different formulations - tablets with different dosages, powder for preparing suspensions for children.

However, in accordance with the international treatment protocol, Amoxiclav is the first-line drug of choice for angina, Sumamed is the second. This means that, in general, priority is given to Amoxiclav, and only when it is contraindicated for any reason, Sumamed is prescribed instead.

In particular, Sumamed can be prescribed:

If the patient has previously taken Amoxiclav or other drugs based on penicillin antibiotics. The opposite is also true: if the patient previously took Sumamed or other drugs based on macrolide antibiotics, he is prescribed Amoxiclav;
If the patient is known to be allergic to penicillins or to β-lactam antibiotics in general;
If according to the results bacteriological research The resistance of the angina pathogen to amoxicillin and clavulanic acid is determined. This is, however, a very rare situation.

Also, when prescribing, the epidemiological situation in a particular area, as well as the individual characteristics of the patient, are taken into account. In some people, clavulanic acid from Amoxiclav causes severe digestive disorders, and it is advisable for them to be prescribed Sumamed as a more delicate drug.

In any case, only a doctor should choose a remedy and only after correct diagnosis of the disease. You cannot prescribe an antibiotic yourself at home based on recommendations on the Internet. This is fraught with severe side effects (cases of death of patients from allergies to antibiotics are known) and fatal dangerous complications tonsillitis.

The drugs that we will consider in this article are antibacterial agents, which means they are capable of destroying pathogenic microflora.

Briefly about the correct choice of antibiotics

Some antibacterial agents are weaker, while others, on the contrary, have a more pronounced effect. In the treatment of infectious diseases, there are certain rules, or the so-called hierarchy (order) of prescribing antibiotics.

In pediatric practice, in principle, as in adults, treatment always begins with penicillins: Augmentin, Amoxiclav, Amoxicillin. Parents often ask the question: “Which antibiotic should I choose for my child, which will work better and more effectively?” It is immediately worth noting that only a doctor is involved in the selection of antibacterial agents.

If we talk about the pathology of the respiratory system, the drugs that we will consider below are considered the most popular in this field of medicine.

To answer the question about choosing antibiotics between amoxiclav, augmentin, summed and amoxicillin (which is better?), we will conduct a brief review of these drugs and find out their features.

Amoxicillin (Russia, Serbia, Vietnam)

A number of bacteria produce penicillinase, which has a detrimental effect on Amoxicillin, as a result of which microorganisms become resistant to this antibiotic.

The drug is available in capsules, tablets and powder for suspension.. All forms are intended for internal use; Amoxicillin is not used for injection.

Main indications for the use of Amoxicillin

The list of indications is quite long:

tonsillitis;
pharyngitis;
laryngitis;
otitis;
angina;
bronchitis;
tracheitis;
frontal sinusitis;
sinusitis;
pneumonia;
meningitis;
endometritis;
erysipelas;
sepsis;
leptospirosis.

Contraindications

Amoxicillin should not be taken in the following cases:

allergic reactions to penicillins and cephalosporins;
intolerance to one of the components of Amoxicillin;
ARVI;
lymphocytic leukemia;
severe gastrointestinal diseases;
Infectious mononucleosis;
bronchial asthma, especially severe;
hay fever;
lactation period, pregnancy (relative contraindication - Amoxicillin is prescribed if necessary);
intestinal dysbiosis.

Side effects

Taking the drug is sometimes accompanied by adverse reactions:

nausea;
violation of taste;
diarrhea;
glossitis;
vomiting (rare);
headache;
conjunctivitis;
hives;
anaphylactic shock (extremely rare);
joint pain;
insomnia;
anxiety;
ataxia;
convulsions;
candidiasis;
the drug reduces the effect of contraceptives.

Amoxiclav (Slovenia)

Amoxiclav is available in tablet form, powder for the preparation of a medicinal suspension (orally) and an injection solution. Tablets are used after 12 years, and when the patient's weight is at least 40 kg. The powder (suspension) is popular in pediatrics and is allowed from the first days of a child’s life.

Main indications for use of Amoxiclav

The antibiotic is used for the following infectious processes:

sinusitis (acute and chronic);
tonsillitis, tonsillopharyngitis;
pharyngitis;
otitis;
bronchitis;
tracheobronchitis;
frontal sinusitis;
nasopharyngitis;
sinusitis (ICD-10 - classification);
pneumonia;
pleural empyema;
pleurisy;
skin, gynecological, genitourinary, bone and other infections.

Contraindications

The drug should not be used in the following cases:

allergic reactions to beta-lactam antibiotics (cephalosporins, penicillins, others);
mononucleosis and during the diagnosis of this disease;
cholestatic jaundice and liver reaction to Amoxiclav;
intolerance to one of the components of Amoxiclav;
lymphocytic leukemia;
severe liver and kidney diseases;
pseudomembranous colitis (relative contraindication, prescribed with caution).

Pregnancy and lactation - the decision to prescribe Amoxiclav is made only according to strict indications.

Side effects

When taking the drug, side effects are usually insignificant. In most cases, Amoxiclav is well tolerated by patients, but the possibility of adverse reactions is not excluded, they are as follows:

nausea;
diarrhea;
vomiting (extremely rare);
headache;
hives;
allergies;
disturbances in blood parameters (thrombocytopenia, increased liver function tests - ALT, AST, eosinophilia, others);
insomnia;
candidiasis;
other.

Price for Amoxiclav tablets 250 mg (15 pieces) is 230 rubles, the cost of powder for a 250 mg suspension is 280 rubles.

Amoxicillin or Amoxiclav - which is better to choose?

The only advantage of Amoxicillin is its cost, it is much cheaper than Amoxiclav.

When choosing these two products, we can conclude: it is better to overpay for a more reliable drug than to then look for analogues, which will still be more expensive. Although it is not a fact that Amoxicillin will be perfect and will solve the problem with pathogenic microorganisms, and even at minimal cost.

Sumamed (Croatia)

The drug has a pronounced antimicrobial effect due to its ability to suppress bacterial cell protein synthesis. Penetrating intracellularly, Sumamed quickly destroys pathogenic flora. It is active against a wide range of pathogenic microorganisms.

Indications

The drug can be used in cases where the following diseases are sensitive to Sumamed, namely:

Diseases of all parts of the respiratory system:

sinusitis;
pharyngitis;
tonsillitis;
tracheitis;
bronchitis;
pleurisy;
bronchopneumonia.

Infectious diseases of the skin:

impetigo;
pyoderma;
erysipelas;
streptoderma;
acne.

Genitourinary pathologies:

cystitis;
pyelonephritis;
pyelitis;
kidney stone disease complicated by bacteria;
glomerulonephritis;
urethritis.

When is Sumamed not used?

The following factors are exceptions to taking the drug:

individual intolerance to the composition of the product;
renal and liver failure;
the age of children for different forms of the drug is limited (tablets - up to 3 years, capsules - up to twelve years, provided that body weight is not lower than 45 kg, for suspension - up to 6 months);
not taken with ergotamine (alkoloid) and dihydroergotamine (alpha blocker).

Relative contraindications:

arrhythmias;
myasthenia gravis;
bradycardia;
pregnancy and lactation;
severe heart diseases of organic nature.

Side effects

The following side effects are possible while taking Sumamed:

itchy skin;
hives;
candidiasis;
pseudomembranous colitis;
changes in blood parameters;
anaphylactic shock;
headache;
insomnia;
rave;
fainting;
impairment of smell, vision, hearing.
noise in ears;
tachycardia;
dyspnea.

The most interesting thing is that doctors consider Sumamed a very effective and safe drug, despite its huge list of “side effects” (see original instructions).

In practice, the remedy really works great, even a disease such as dry pleurisy goes away in three days. Short courses of therapy, as a rule, do not entail side effects.

Price for Sumamed depends on the form and dose of the drug, for example, capsules (250 mg) No. 6 cost 460 rubles, tablets (500 mg) No. 3 - 430 rubles, powder for suspension - 200 rubles.

These drugs are completely different, belong to different groups, and differ in the main active ingredient. Amoxiclav is allowed to be used from the first months of life, Sumamed - from 6 months. Amoxiclav is cheaper, but Sumamed has short courses of treatment. It is usually prescribed for 3 days, and penicillins are taken for a week. The speed of action of Sumamed reduces the duration of the disease.

Antibiotics for sore throat

Azithromycin is very often used in pediatric practice, but for successful treatment you need to know the correct instructions for using Azithromycin for children.

Independent selection of antibacterial agents is excluded due to the danger of the emergence of resistant (resistant) forms of the disease. Complex treatment of sore throat, where antibiotics play a leading role, allows you to eliminate the infectious process within five days and give a chance to exclude relapse of the disease in the future. Be healthy!

How to treat a sore throat with antibiotics from Doctor Komarovsky

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