What is better Texamen or Actovegin. What is the drug Texamen prescribed for? Components of the composition, form of production

The drug Texamen is a drug that has anti-inflammatory, analgesic, and antipyretic effects. The products are produced in the form of film-coated tablets, also in the form of a lyophilisate intended for the preparation of a solution for intravenous and intramuscular injection. According to its pharmacological affiliation, Texamen belongs to the group of non-steroidal anti-inflammatory compounds.

Dosage form

The drug Texamen is produced in the form of a lyophilisate intended for the preparation of a solution for intravenous and intramuscular administration, as well as in the form of tablets intended for oral administration.

Description and composition

The drug is produced in two dosage forms. Film-coated tablets are yellow with a brown tint. The elements have an oval, biconvex shape. A mark is applied on one side. The kernel in cross section has a bright yellow color. The lyophilisate for preparing the solution is a homogeneous yellow powder with a greenish tint. The cardboard package contains one bottle of powder and one ampoule of solvent. One tablet of the drug contains tenoxicam at a dose of 20 mg. The additional components are: iron oxide, macrogol, hypromellose, titanium dioxide, lactose monohydrate, corn starch, pregelatinized starch, magnesium stearate, opadry yellow. 1 bottle of lyophilisate contains tenoxicam at a dose of 20 mg. The auxiliary components are: sodium hydroxide, sodium trometamol, sodium metabisulfite, sodium hydroxide.

Pharmacological group

Texamen belongs to the group of non-steroidal anti-inflammatory drugs. In addition to anti-inflammatory, antipyretic and analgesic effects, active substance also provides prevention of platelet aggregation. The anti-inflammatory effect of the active component provides suppression of the activity of cyclooxygenase, which takes part in the production of arachidonic acid, due to which the synthesis of prostaglandins is suppressed.

Tenoxicam inhibits lipase activity and has no effect direct action. The drug inhibits some leukocyte activity, including phagocytosis and the release of istomin. The active substance is quickly and completely absorbed from gastrointestinal tract, the maximum content of the substance in the blood plasma is achieved 2 hours after oral administration. When using the drug after meals, the rate of absorption decreases. The average half-life is 70 hours. The active substance is completely absorbed. Its bioavailability is 100%. The substances bind to blood proteins by 99%. The active component penetrates well into the synovial fluid and is characterized by a long half-life. The substance is eliminated from the patient’s body through urine and feces.

Indications for use

The list of indications for use of the drug can be presented as follows:

bursitis;
ankylosing spondylitis;
articular syndrome during exacerbation of gout;
rheumatoid arthritis;
tenosynovitis;
osteoarthritis;
moderate pain syndrome;
dental and headache;
neuralgia;
myalgia;
lumbago;
sciatica;
inflammatory and degenerative diseases of the musculoskeletal system;
pain from burns and injuries.

The product reduces pain and inflammation at the time of use; it has no effect on the course and progression of the disease.

for adults

Patients of this age category may use the drug when identified and indicated for use. Medicines should be prescribed with extreme caution to persons old age and patients with liver and kidney diseases. The drug is not prescribed to patients with diseases of the cardiovascular system. Before using the drug, you should obtain a full consultation with your doctor.

for children

The drug Taxamen is not used in pediatric practice. There is no experience in using the composition in children. The active component may cause the appearance adverse reactions The child has.

Medications should not be used during pregnancy and breastfeeding. Medicinal composition may cause acute adverse reactions.

Contraindications

The list of contraindications to the use of the drug can be presented as follows:

blood pathologies;
exacerbation of gastritis;
hyperkalemia;
erosive and ulcerative lesions;
lesions of the gastrointestinal tract;
gastrointestinal bleeding;
diseases of the vestibular apparatus;
liver damage, kidney disease;
hypocoagulation;
inflammatory lesions of the gastrointestinal tract;
pregnancy period;
individual intolerance to the components of the drug.

The drug is prescribed with extreme caution to patients with chronic renal and chronic heart failure. Subject to the rules of administration, the drug can be used for coronary disease hearts. Dose adjustment is required for elderly people.

Applications and dosages

The drug in tablet form is recommended to be taken orally at the same time after meals. Injection solution administered intramuscularly or intravenously. Frequency of use is 1 time per day. Average single dose is 20 mg. With prolonged use, the dose is halved. In case of acute pain syndrome, the dose can be increased on the recommendation of the attending physician.

for adults

Patients of this age category can use medications when indications for use are identified. The drug composition is well tolerated, adverse reactions are extremely rare. The drug is prescribed with extreme caution to elderly people, as well as to patients with diseases of the cardiovascular system and kidneys.

for children

The use of the drug in pediatric practice is strictly prohibited.

for pregnant women and during lactation

The use of the drug during pregnancy and breastfeeding is prohibited.

Side effects

During the use of the medication, adverse reactions may be observed, namely a burning sensation in the stomach, abdominal pain, nausea, diarrhea, flatulence, abdominal pain, anorexia, liver dysfunction, perforation of the intestinal wall, heart failure, myocardia, increased blood pressure, leukopenia, monocytosis, anemia, thrombocytopenia, increased bilirubin in the blood serum.

Interaction with other drugs

Anticoagulants and antiplatelet agents enhance the effect of the drug. Other non-steroidal anti-inflammatory drugs increase the risk of adverse reactions. Medicines with antihypertensive effects reduce the effectiveness of the active component. Hormones of the adrenal cortex increase the likelihood of adverse reactions.

special instructions

Special instructions regulating the rules for using the drug should be checked with your doctor.

Overdose

There is currently no accurate information about overdose. Conversion of doses may cause serious consequences for the patient's health.

Storage conditions

The medicine should be stored at a temperature of no more than 25 degrees. Maximum duration Storage period is 3 years from the date of production. The drug is dispensed from a network of pharmacies by prescription. It is prohibited to use the medicinal composition with expired suitability.

Analogs

The drug Texamen does not have full-fledged analogues with a similar composition. Other non-steroidal anti-inflammatory drugs can be considered as analogues of the drug.

The drug is a popular drug used for various diseases musculoskeletal system. The composition has a pronounced analgesic, antipyretic and anti-inflammatory effect. The product can be used by children over 12 years of age. The drug is distributed to the population through a network of pharmacies only upon presentation of a prescription.

Price

The cost of the drug Texamen averages 677 rubles.

"Texaman" belongs to the group non-narcotic analgesics. The active ingredient of the drug is tenoxicam, which is non-steroidal substance from the oxicam group.

Effect of the drug

The drug has an anti-inflammatory effect, has a pronounced antipyretic effect and is a good pain reliever.

This effectiveness is due to the ability of the drug to inhibit the activity of cyclooxygenesis. The medicine slightly inhibits the metabolism of arachidic acid, reduces the amount of histamine released, and this leads to the inflammatory process gradually decreasing.

The main absorption process of the drug occurs in the digestive tract. The highest concentration of the active substance in the body is observed 2 hours after ingestion. Metabolic processes occur in the liver by 99%.

"Texamen": instructions for use

Analogues have detailed instructions. The drugs are used to relieve musculoskeletal pain during the inflammatory process in the following diseases:

osteoarthritis;
rheumatoid arthritis;
gout, which is accompanied by joint disorders;
osteochondrosis.

The drug is also effective for neuralgia, bursitis and injuries.

"Texamen": instructions, analogues

The drug "Texamen", like its analogues, is not recommended for long-term use; it can be used for no more than 7 days in a row. In extreme cases, with severe pain, the duration of treatment can be 14 days.

The drug can be administered intramuscularly and intravenously, or taken orally.

The daily dose should not exceed 20 mg of the active substance. Severe attacks gout can be relieved by using the drug with daily dose 40 mg, but not more than 2 days in a row.

Analogs

There are substitutes for the medicine "Texamen". An analogue, one of the most famous, is “Movalis”; they can also include “Diclofenac”. These medications are as highly effective as Texamen in removing pain syndrome. However, the drugs have their pros and cons.

"Texamen" has a prolonged effect, but rather "non-selectively" relieves pain. "Movalis" has a smaller list of diseases for which the medicine relieves painful sensations, at the same time does not harm the functioning of the gastrointestinal tract, although its use in loading doses may harm the heart muscle.

"Diclofenac" is an analogue of "Texamen", has a low cost, copes well with pain, but is very harmful to the stomach.

Simply put, if you have stomach problems, you should not use Diclofenac, and it is better to replace Texamen with Movalis. If there are no health problems, then for quick and effective removal pain, you can use a cheap analogue - Diclofenac.

A popular analogue of "Texamen" is the drug "Oxyten". It is often used in the presence of pathologies associated with the musculoskeletal system. One tablet of the drug contains 20 mg of tenoxicam. Therefore, you should not take more than 1 tablet more than once a day.

Other drug analogues

In addition to these popular drugs, there are many more analogues of Texamen, produced both in tablet form and in injection form. It is recommended to use injections in severe cases, when the pain is too severe; in other cases, it is better to use tablets.

Brief description of some analogues

"Lorakam" is used for minor pain, in case of exacerbation of osteoarthritis.

"Xefocam" is used in the presence of moderate or severe pain caused by degenerative rheumatic changes.

"Revmoxicam", like "Xefocam", is used for severe exacerbation of pathology associated with the musculoskeletal system; it can be used for a limited amount of time. Available in tablet form and for injection.

“Naklofen” is an analogue of “Texamen”, it is also used as an analgesic and not only for problems with the musculoskeletal system, it is used in dentistry and after surgery to relieve pain.

Contraindications

You cannot use the original drug or any analogue of Texamen in tablets and injections if you have a number of diseases:

strong or mildly manifested gastrointestinal pathologies, peptic ulcer or gastritis;
high blood sugar or diabetes;
liver pathologies;
problems with the vestibular apparatus;
heart failure;
hearing problems.

In addition, if there is a history of the “aspirin triad” or lactose intolerance, the drug is also not used to relieve pain. Medicines with the active ingredient tenoxicam and its analogues are not used in pediatrics.

The drug is used with great caution in the presence of liver pathology; if the transaminase level increases significantly, the drug is immediately discontinued.

Availability arterial hypertension and heart failure is also not an absolute contraindication, but the presence of such diseases requires monitoring the patient’s condition.

It is not recommended to use Texamen if you plan to surgery, due to the drug’s ability to reduce platelet aggregation.

You cannot combine salicylates and drugs with the active substance tenoxicam.

"Texaman" and pregnancy

The drug is prohibited for use during pregnancy and breastfeeding. "Texamen" can help increase the gestation period and weaken labor activity.

Possible side effects

Before using the drug, you must consult a doctor. If you decide to self-treatment, then be sure to carefully read the instructions and become familiar with any possible problems side effects in order to stop using the drug in time.

Side effects from digestive tract:

bowel dysfunction: both diarrhea and constipation;
bloating and flatulence;
heartburn;
vomit;
pain in the epigastric region;
stomatitis.

Side effects of this group occur no more often than in 1.4% of cases.

Problems that may appear from the cardiovascular and circulatory systems:

tachycardia;
increased blood pressure;
decreased level of electrocytes;
decrease in platelet count.

From the outside nervous system The following side effects are possible:

drowsiness;
dizziness;
tinnitus and headaches;
depressive state, up to the appearance of irritability;
hyperactivity;
changes related to perception environment, through the eyes and ears.

Skin disorders when using tablets occur in 2.5% of patients and are characterized by the following symptoms:

hives;
rash with itching;
photodermatitis;
extremely rare, but Lyell's syndrome occurs.

Problems with genitourinary system occur in 1.2% of cases and manifest themselves as a decrease in the level of nitrogen and urea.

Very rarely, but still there are cases of an allergic reaction to the drug, including bronchospasms and Quincke's edema.

During treatment, there may be mental disorders, are observed in 1.7% of patients. Metabolic disorders were observed in only 1% of cases.

Concentrating while using Texamen

Treatment with the drug requires extreme caution when driving. Also, if possible, limit activities associated with psychomotor reactions and increased concentration.

Interaction with other drugs

"Texamen" and analogues enhance the effect of anticoagulants. The simultaneous use of diuretics and texamen is not allowed; if such a combination is unavoidable in treatment, then systemic monitoring of renal function is necessary to prevent renal failure.

If diabetes mellitus is suspected, the drug can be used only if blood glucose levels are monitored.

"Texamen" and its analogues cannot be combined with other drugs in the same syringe.

Therefore, you must read the instructions for the drug "Texamen". Analogues also have all detailed information instructions for use.

Price policy

The drug "Texamen" cannot be called expensive. A bottle for preparing an injection solution costs no more than 250 rubles. Considering that the drug cannot be used constantly, its cost is low. But "Texamen" has cheaper analogues.

The tablet form of the medicine does not exceed the cost of 300 rubles for 10 pieces. The price always depends on the form of release and, naturally, the place where the pharmacy is located. At the same time, there are cheaper analogues of the drug, for example Diclofenac.

"Texaman": reviews, analogues

For the most part, painkillers are used in adulthood and older age, when there are chronic diseases and sometimes it is impossible to cope with them without painkillers.

Despite the effectiveness of Texamen and its analogues, the drugs have many contraindications and are therefore not recommended for independent use.

At the same time, some people find it impossible to even fall asleep due to pain in the back or in places where there were previous injuries. In most cases, the effectiveness of the drug is high level, which is shared by people who use Texamen (ampoules), analogues of the drug.

Despite its high effectiveness, opinions about the drug are mixed. Some people are delighted with the drug and its instant action, while others, on the contrary, claim that there is no talk of any reduction in pain. But bad reviews are often due to the fact that patients forget about the strong effect of the active substance on the stomach. If problems with the gastrointestinal tract are suspected, it is recommended to use drugs simultaneously with Texamen to normalize the functioning of the stomach.

It is also possible to experience dry mouth after using the tablet form of the drug, but, as a rule, the injection form of Texamena eliminates the possibility of any side effects. Moreover, administering the drug intramuscularly is an absolutely painless procedure. You should never forget about the time limit for using tablets and injections.

In conclusion, it should be noted that the drug "Texamen" is quite effective remedy to relieve pain, but requires professional approach for use due to the presence of a large list of contraindications and side effects. Therefore, you should not use the drug and its analogues on your own, but rather consult your doctor first.

Non-steroidal anti-inflammatory drugs - drugs that you can do without medical practice it would be practically impossible. They are used to treat many diseases and help cope with various problems. Texamen is one of the most effective representatives of his group. It works quickly and accurately, but despite this, it is not suitable for everyone. Sometimes Texamen has to be replaced with analogues. Fortunately, there are a lot of generic drugs available today. Therefore, everyone can find the most suitable remedy for themselves.

Composition and action of Texamena

Texamen belongs to the group of oxicams. This medication is an excellent analgesic that relieves pain and fights inflammatory processes. The main active ingredient in the drug is tenoxicam. In addition to it, Texamen contains excipients. In tablets it is:

starch;
lactose;
talc;
Magnesium stearate.

Texamen ampoules contain:

trometamol;
mannitol;
sodium hydroxide;
magnesium edetate;
sodium metabisulfide.

The action of Texamen and most of its analogues is based on platelet aggregation. The main substances, when entering the body, affect cyclooxygenase isoenzymes, thereby helping to reduce prostaglandin synthesis and pain relief. Tenoxicam, contained in large quantities in Texamen, affects white blood cells, preventing their accumulation at the site of inflammation.

Indications for use of Texamen and its substitutes

The main purpose of Texamen is the treatment of inflammatory degenerative diseases occurring in the musculoskeletal tissue. Medication is prescribed for the following diagnoses:

arthritis;
gout;
neuralgia;
periarthritis;
osteochondrosis;
lumbago;
osteoarthritis;
myositis;
spondylitis;
tendinitis;
injuries;
ligament damage.

As practice has shown, Texamen can also be used to treat headaches and menstrual pain, burns, and combat high fever.

Diclofenac, Movalis or Texamen - which is better?

And Movalis are the most famous analogues of Texamen. They allow you to achieve the same treatment results as the original medicine. Each of the means has its own pros and cons. Thus, Texamen is characterized by a long-lasting but indiscriminate effect. Movalis acts selectively and does not harm the stomach, but in large quantities it can be dangerous for the heart. Diclofenac is available and effective, but is bad for the stomach.

Simply put, if you are suffering from stomach problems, it is best to replace Texamen with Movalis. Healthy people can get by with the more economical Diclofenac.

What else can replace Texamen?

Both Texamen and almost all of its substitutes are available in two forms: tablets and injections. Mostly, experts offer treatment with tablets. It is customary to resort to injections in the most difficult cases, when the pain syndrome is clearly expressed.

The most popular generics of Texamen look like this:

For frequent migraines, periodic pain, spasms and cramps in the muscles of the legs and back, it is necessary to take analgesics. Doctors recommend a drug that has an analgesic effect on the body. The medicine is called Texamen. The product is not addictive and quickly copes with unpleasant sensations, soothing the source of pain, rather than suppressing its symptoms.

Composition of the drug

Texamen is available in two dosage forms: tablets and powder for the preparation of solutions. The capsules are coated and have yellow with a brown tint. Their shape is round, both sides are convex, with a risk on one side. If you cut the tablet crosswise, you can see a bright yellow core. One package contains a cell with ten pieces.

Powder for intramuscular and intravenous injections has a yellow-green tint. One box contains a bottle of lyophilisate and an ampoule with a liquid in which it is dissolved. Also, the package may not contain a solution.

One tablet contains 20 mg of the active substance - tenoxicam, as well as yellow iron oxide, talc, gelatinized starch, macrogol, titanium dioxide, lactose and hypromellose, magnesium stearate and dye. The powder consists of the main component and mannitol, sodium hydroxide, trometamol and disodium edetate.

Pharmacological characteristics

Texamen is classified as a non-narcotic and non-steroidal anti-inflammatory drug. In addition to the fact that the drug has an antipyretic and analgesic effect on the body, it prevents the grouping of platelets inside blood vessels. Inflammation is suppressed by deactivating substances that take part in the metabolism of arachidonic acid. Due to this, the synthesis of prostaglandins slows down.

Tablets and injections suppress the work of leukocytes: the release of histamine and phagocytosis reduces the number of active radicals in the inflammatory focus. The drug does not decompose into substances in the digestive tract. It is absorbed into the blood, its maximum content in the body is reached two hours after administration. If you take the tablets after meals, their absorption rate will slow down.

The active substance is eliminated by half after 70 hours. The drug is 100% of the blood and is 99% protein bound. Due to the fact that Texamen leaves the body within several days, it can only be taken once a day. Most - two thirds - is excreted in the urine, the rest - in feces. The drug does not accumulate during long-term use.

Instructions for use

The medicine is prescribed to treat various types of inflammation, relieve pain and fever. The instructions for use of Texamen tablets indicate several indications:

pain from injuries and burns;
inflammation of the musculoskeletal system;
lumbago and epicondylitis, which are accompanied by painful shock;
moderate or mild discomfort felt by the patient with migraine, neuralgia, diseases of the teeth and head;
bursitis and myalgia;
osteoarthritis and gout.

Injections of a powder solution are made for spondylitis, tendovaginitis, articular syndrome, algodismenorrhea and sciatica. They also relieve inflammation during rheumatoid arthritis, arthralgia and allergic reactions. The drug helps relieve pain, redness, and swelling at the time of use. But it does not slow the progression of the disease or relieve other symptoms. During colds, Texamen is prescribed in combination with antibiotics and drugs that fight runny nose and cough.

The drug is not used in veterinary medicine. The active substance of the drug has a strong effect on the body. The digestive tract of cats and dogs may not tolerate the side effects of Texamen. If the immune system is weakened, death can occur. Injections of a powder solution should also not be done to reduce fever and eliminate pain or inflammation; it is better to use other medications that the veterinarian will prescribe.

Tablets and injections have a significant list of contraindications. They are divided into relative, which allow the use of Texamen in certain cases, and absolute, which completely exclude therapy with the drug. First group:

severe renal and heart failure;
ischemic disease;
diabetes;
swelling of the legs, face and hands;
somatic diseases of the last stages;
smoking and alcoholism;
peripheral artery problems;
hypertension, dyslipidemia, hyperlipidemia;
cerebrovascular diseases;
presence of Helicobacter pylori infection in the body;
patient age over 50 years;
combination with anticoagulants, inhibitors and antiplatelet agents.

If there is one of absolute contraindications It is strictly forbidden to use Texamen. Otherwise, a complication of the ongoing disease may occur, as well as the development and intensification of side effects.

This group includes:

decreased hearing;
severe stages of gastritis;
diseases of the blood and circulatory system;
ulcers and erosions of the digestive tract;
hyperkalemia;
bleeding in the stomach or intestines;
problems with the vestibular system;
developing kidney and liver diseases;
bronchial asthma, diseases of the nose, paranasal sinuses, tonsils;
hemophilia and hypocoagulation;
inflammation digestive systems s;
glucose deficiency in the body;
allergic reactions to the components of the drug;
pregnancy and lactation period.

Some patients may experience side effects from therapy. Texamen causes a decrease in the amount of hemoglobin and granulocytopenia, sometimes dizziness, drowsiness and depression, blurred vision and hearing, headache and tinnitus, and agitation are possible. Rarely, tachycardia and increased blood pressure, heart failure and a burning sensation in the stomach occur. Nausea and vomiting, flatulence, anorexia and stomatitis, bleeding in the uterus, intestines, rectum or gums may develop.

Also to side effects include constipation or diarrhea, anemia and thrombocytopenia, increased serum bilirubin. Some patients experience rash and urticaria, itching and photodermatitis. The level of nitrogen in urea increases, bleeding occurs more slowly. Mental and metabolic disorders are also possible.

special instructions

The tablets are taken orally every day at the same time. It is advisable to do this after eating food. The solution must be injected into the muscles or veins once a day. The dose for all patients should not exceed 20 mg if therapy is continued long time, then it is reduced by half. Severe stages of gout include the administration of 40 mg of the drug in the first two days of treatment, then the usual amount is used.

In case of an overdose of the drug, side effects may increase; treatment depends on the symptoms manifested. During treatment, it is necessary to constantly diagnose the condition of the kidneys and liver, as well as check the level of platelets in the blood and glucose levels. Two days before the tests, stop using Texamen, as before surgery.

The use of tablets in patients with heart failure may cause water and sodium retention in the body. If it is necessary to reduce the risk of a protective reaction of the digestive tract, then you need to adhere to the minimum dose of the drug and reduce the duration of therapy as much as possible.

During treatment, dizziness and drowsiness develop, so you should not take pills or give injections before driving. Texamen is not prescribed to pregnant women and nursing mothers. The active substance of the drug can delay labor and weaken muscles during contractions. Changes in allergy sufferers appearance- the eyes itch and turn red, the nail plate changes color and structure, the hair becomes dull, and skin hives appear.

Treatment is contraindicated in patients with chronic diseases kidneys and liver, and older people can take pills only under the constant supervision of their doctor. No studies have been conducted on the effects of Texamen on children's body. Therefore, doctors rarely prescribe the drug to patients under 18 years of age. During therapy you should stop using alcoholic drinks, as well as from smoking. Nicotine and alcohol weaken the effect of Texamen and cause increased side effects.

Using Texamen with others medicines can cause various effects - from enhancing the effects of all drugs on the human body to worsening the patient’s condition. You should not combine tablets and injections with the following medications:

myelotoxic solutions - their hepatotoxicity increases;
anticoagulants and fibrinolytics - side effects worsen health;
other non-steroidal anti-inflammatory substances - increases the risk of negative effects on the digestive system;
diuretics and drugs with a hypotensive effect - their beneficial functions are reduced;
estrogens and hormones based on the adrenal cortex - their side effects develop;
the effect of uricosuric drugs is practically canceled;
the hypoglycemic effect of sulfonylurea derivatives is enhanced.

Do not combine Texamen with methotrexates, as it increases their content in the blood, antacids and cholestyramines, which weaken its effect. Barbiturates, ethanol, phenytoin, antidepressants, rifampicin and phenylbutazone increase the production of active metabolites. During combination therapy, you must first consult with your doctor and study in detail the side effects of all medications.

There are quite a few drugs with similar effects in pharmacies. Among analogues of Texamen there are several products:

Tenoctil;
Artoxan;
Movalis;
Tobitil;
Meloxicam;
Tenikam.

Tenoctil;
Artoxan;
Movalis;
Tobitil;
Meloxicam;
Tenikam.

These medications also relieve inflammation and lower temperature, eliminating pain. The tablets can slow down the elimination of lithium from the body, so patients taking medications with high levels of this substance suffer from intoxication. For the treatment of arthritis, Arava, Wobenzym, Decortin, Dicloran, Dolgit and Ibuprofen, Meloxam, Ketonal, Panavir and Flamax are additionally used.

In pharmacies, the drug is sold exclusively by prescription; the price of Texamen tablets is 360-370 rubles per pack. Store the drug in a dark place at a temperature not exceeding 25 degrees. It must be protected from access by pets and children. The expiration date reaches three years. Before purchasing, you must consult a doctor, read the instructions for use, the price of Texamen injections and reviews of patients who have already undergone therapy.

"Texamen" is an NSAID, a representative of oxicams. The drug eliminates inflammatory processes and pain, can reduce fever. Below is a description of the drug "Texamen", analogues, instructions for use.

Release form, composition

The drug can be purchased in coated tablets and in the form of an injection solution. The active ingredient is tenoxicam (20 mg). TO excipients include pregelatinized starch, magnesium stearate, talc. Lactose is also used as an additional ingredient. The tablet shell consists of yellow iron oxide, polyethylene glycol 400, hydroxypropyl methylcellulose.

Pharmacological properties of the drug

Both the original drug and the Texamena analogue selected by the doctor will help get rid of pain, inflammation and fever, and prevent platelet aggregation. The action of the drug is based on suppressing the activity of the COX-1 and COX-2 isoenzymes. Thanks to the use of the drug in the body, the process of producing prostaglandins slows down, and fewer leukocytes accumulate in the inflamed area. The anti-inflammatory effect is observed approximately one week after the start of treatment. The effect of the drug lasts for a long time.

Absorption occurs quickly, the drug is completely absorbed, but this process is slower if the tablet is taken before meals. Bioavailability is 100%, there is almost complete communication with proteins that are present in the blood plasma. The maximum concentration of the drug is determined 120 minutes after its use. Half-life occurs within 72 hours. The components of Texamen enter the synovial fluid. The drug has the ability to pass through histohematic barriers. Metabolism occurs in the liver; as a result of hydroxylation, 5-hydroxytenoxicam is formed. Most of the drug is excreted by the kidneys (inactive metabolites), the rest by the liver (bile).

Indications for use

Both the original and the analogue of “Texamen” (injections, tablets) are prescribed to relieve pain that is mild or moderate:

headache, toothache;
skin lesions due to burns;
damage received due to traumatic exposure;
algodismenorrhea;
migraine;
neuralgia;
myalgia;
arthralgia.

The drug is indicated for tendovaginitis, bursitis, osteoarthritis, rheumatoid arthritis. Texamen is used to treat ankylosing spondylitis. It is used to eliminate articular syndrome in gout during an exacerbation.

Contraindications

In this list - increased sensitivity to the components of the drug, childhood(less than 18 years old), bearing a child, breast-feeding. An analogue of "Texamen" is prescribed when treatment with the original drug is unacceptable. "Texamen" is not used in the following cases:

lesions of the hematopoietic system;
pathological conditions vestibular apparatus;
severe gastritis;
lesions of the gastrointestinal tract - bleeding, erosive-ulcerative damage (pathological conditions in the anamnesis are also a contraindication to treatment with Texamen);
hearing impairment;
hypocoagulation;
deficiency of glucose-6-phosphate dehydrogenase;
hemophilia;
“aspirin” triad;
renal and liver failure.

Constant monitoring of health status is required when treating elderly patients, patients with diabetes mellitus, hypertension, a tendency to edema, heart failure.

Treatment with Texamen

Both the original and the analogue of “Texamen” (injections, tablets) are used with the determination of an individual dose for each patient. Basically, one tablet is taken orally. The medication is taken once and should be taken daily at the same time after eating. With long-term use of the drug, 10 mg of the drug is required for daily use. For patients with gout when it occurs acute attack It is recommended to take 40 mg of the drug for the first two days, the rest of the time (five days) - one tablet per day.

Side effects

Undesirable reactions of the body can occur from the nervous, cardiovascular and digestive systems. Possible negative reactions hematopoietic organs to the drug used, for example, an analogue of Texamena. In rare cases, an allergy develops, which manifests itself as Stevens-Johnson, Quincke's edema, urticaria, itching, skin rash. Sometimes some laboratory values change. Other side effects include edema syndrome, excessive sweating, impaired renal function, and bronchospasm. In case of overdose, treatment is carried out aimed at eliminating its symptoms.

special instructions

During the period of therapy, monitoring of peripheral blood is required; it is also necessary to regularly check the condition of the kidneys and liver, determine the level of glucose in the blood, and the prothrombin index. Sometimes a doctor may prescribe an analogue of Texamen.

In cases where it is necessary to determine 17-ketosteroids, treatment is interrupted for a while. The drug should be stopped two days before the study. It must be canceled before execution surgical interventions(a few days before surgery).

Taking the drug is associated with the risk of water and sodium retention and their prolonged removal from the body. This result is possible when simultaneous use"Texamena" and diuretics for the treatment of patients with cardiac insufficiency and hypertension.

Patients with a history of kidney disease may develop papillary necrosis,

Cost of the drug, analogues, reviews

The Texamen analogue is cheaper than the original product. The solution can be purchased for 205-215 rubles, the approximate cost of tablets is 270-300 rubles. Analogues with identical active substances and analogues that have a similar effect are produced. There is a foreign substitute for Tenikam; this drug is based on the same active ingredient as Texamen. You can also purchase domestic analogue"Texamena." The doctor must decide which one to choose.

"Nise" is also medicine foreign-made, they can replace the original medicine. This analogue contains another active substance, however, the medication has an effect similar to action"Texamena." With its help, it is possible to forget about pain for a long time and quickly eliminate the inflammatory process.

The domestic analogue of “Texamena” is no worse than the imported one. "Texaman" has a large number of substitutes, choice suitable remedy carried out jointly with the doctor. It can be replaced with Naproxen, Polcortolone, Flamax or Naklofen. Treatment with the use of Endoxan, Polyoxidonium, Prednisolone, Nalgesin is possible. As an analogue, the use of “Feloran” is allowed.

The Russian analogue of "Texamena" is "Diclofenac". This is a fairly well-known substitute original drug. As a result of its use, a similar healing effect. "Diclofenac" has a low cost, so it is accessible means, however, treatment with such a medicine can negatively affect the condition of the stomach. For this reason, doctors do not prescribe it to patients who have problems with the gastrointestinal tract. "Diclofenac" is a reliable analogue, but it is not suitable for everyone.

As reviews show, many people are prescribed Texamen to eliminate pain. Patient reviews are positive, which is due to the drug fulfilling its tasks. Side effects usually do not develop.